Jund (jun D proto-oncogene) - Rat Genome Database

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Gene: Jund (jun D proto-oncogene) Mus musculus
Analyze
Symbol: Jund
Name: jun D proto-oncogene
RGD ID: 735347
MGI Page MGI
Description: Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription coregulator binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cellular response to calcium ion; osteoblast development; and positive regulation of osteoblast differentiation. Predicted to be located in nucleoplasm. Predicted to be part of protein-DNA complex; transcription factor AP-1 complex; and transcription repressor complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and limb. Orthologous to human JUND (JunD proto-oncogene, AP-1 transcription factor subunit).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; JunD-FL isoform; Jund1; MGC6245; transcription factor AP-1 subunit JunD; transcription factor jun-D; transcription factor JunD
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,150,389 - 71,153,265 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,151,599 - 71,153,265 (+)EnsemblGRCm39 Ensembl
GRCm38870,697,739 - 70,700,616 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,698,949 - 70,700,616 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,221,638 - 73,224,515 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,627,938 - 73,629,605 (+)NCBIMGSCv36mm8
Celera873,254,240 - 73,257,113 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Pimaric acid  (ISO)
(-)-anisomycin  (ISO)
(S)-amphetamine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5'-S-methyl-5'-thioadenosine  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
ampicillin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atazanavir sulfate  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
cisplatin  (ISO)
clozapine  (ISO)
cocaine  (EXP,ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
coumarin  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (EXP,ISO)
depsipeptide  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (ISO)
dieldrin  (ISO)
diuron  (ISO)
dobutamine  (ISO)
emodin  (ISO)
etoxazole  (EXP)
fenthion  (EXP)
fenvalerate  (ISO)
fluconazole  (ISO)
flufenoxuron  (EXP)
flutamide  (EXP)
folic acid  (EXP)
formaldehyde  (ISO)
fucoidan  (ISO)
fumonisin B1  (EXP)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
isoflavones  (ISO)
L-methionine  (EXP)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (EXP)
luteolin  (ISO)
mechlorethamine  (EXP,ISO)
metformin  (ISO)
methapyrilene  (ISO)
methidathion  (EXP)
methimazole  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
metoprolol  (ISO)
microcystin-LR  (EXP)
motexafin gadolinium  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (EXP)
Nodularin  (ISO)
obeticholic acid  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentobarbital  (ISO)
phencyclidine  (ISO)
phenobarbital  (EXP)
phenylephrine  (EXP)
phlorizin  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phorone  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
pomalidomide  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
prothioconazole  (ISO)
putrescine  (ISO)
quercetin  (ISO)
quinomethionate  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
retinyl acetate  (EXP)
rotenone  (EXP,ISO)
sertraline  (ISO)
silicon dioxide  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
triadimefon  (ISO)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (ISO)
triticonazole  (ISO)
tunicamycin  (EXP,ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vanillin  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cell cycle  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal sexual interaction  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal T-helper 2 physiology  (IAGP)
ascites  (IAGP)
asthenozoospermia  (IAGP)
cardiac hypertrophy  (IAGP)
cardiac interstitial fibrosis  (IAGP)
congestive heart failure  (IAGP)
decreased body weight  (IAGP)
decreased circulating follicle stimulating hormone level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating growth hormone level  (IAGP)
decreased fibroblast proliferation  (IAGP)
decreased growth hormone level  (IAGP)
decreased liver triglyceride level  (IAGP)
decreased liver weight  (IAGP)
decreased response of heart to induced stress  (IAGP)
decreased susceptibility to diet-induced hepatic steatosis  (IAGP)
decreased total fat pad weight  (IAGP)
dilated cardiomyopathy  (IAGP)
early cellular replicative senescence  (IAGP)
edema  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
increased cell proliferation  (IAGP)
increased cellular sensitivity to ultraviolet irradiation  (IAGP)
increased circulating cholesterol level  (IAGP)
increased susceptibility to endotoxin shock  (IAGP)
increased T cell proliferation  (IAGP)
lethargy  (IAGP)
liver inflammation  (IAGP)
liver vascular congestion  (IAGP)
male infertility  (IAGP)
oligozoospermia  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
pulmonary vascular congestion  (IAGP)
respiratory distress  (IAGP)
teratozoospermia  (IAGP)
visceral vascular congestion  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility. Behmoaras J, etal., Nat Genet. 2008 May;40(5):553-9.
2. Obesity-induced activation of JunD promotes myocardial lipid accumulation and metabolic cardiomyopathy. Costantino S, etal., Eur Heart J. 2019 Mar 21;40(12):997-1008. doi: 10.1093/eurheartj/ehy903.
3. Protein kinase p-JNK is correlated with the activation of AP-1 and its associated Jun family proteins in hepatocellular carcinoma. Guo L, etal., Life Sci. 2005 Aug 26;77(15):1869-78. doi: 10.1016/j.lfs.2005.03.019.
4. Selective participation of c-Jun with Fra-2/c-Fos promotes aggressive tumor phenotypes and poor prognosis in tongue cancer. Gupta S, etal., Sci Rep. 2015 Nov 19;5:16811. doi: 10.1038/srep16811.
5. Structure, chromosome mapping, and expression of the mouse Lyl-1 gene. Kuo SS, etal., Oncogene 1991 Jun;6(6):961-8.
6. Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice. Latasa MU, etal., PLoS One. 2010 Dec 29;5(12):e15690. doi: 10.1371/journal.pone.0015690.
7. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. MGD IEA MGD IEA
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Mouse MP Annotation Import Pipeline RGD automated import pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Structural organization of the mouse glycophorin A gene. Terajima M, etal., J Biochem (Tokyo) 1994 Nov;116(5):1105-10.
15. Overexpression of members of the AP-1 transcriptional factor family from an early stage of renal carcinogenesis and inhibition of cell growth by AP-1 gene antisense oligonucleotides in the Tsc2 gene mutant (Eker) rat model. Urakami S, etal., Biochem Biophys Res Commun. 1997 Dec 8;241(1):24-30.
Additional References at PubMed
PMID:1326990   PMID:1351769   PMID:1605850   PMID:1675193   PMID:1793595   PMID:1887331   PMID:2104845   PMID:2108401   PMID:2493644   PMID:2504580   PMID:3142691   PMID:7671815  
PMID:7700631   PMID:7713493   PMID:8124713   PMID:8134124   PMID:8415709   PMID:8474450   PMID:8649810   PMID:8661125   PMID:8662221   PMID:8668199   PMID:8761296   PMID:8833158  
PMID:8833245   PMID:8884266   PMID:8889548   PMID:9000138   PMID:9060410   PMID:9204924   PMID:9457687   PMID:9753632   PMID:9858769   PMID:10349636   PMID:10352021   PMID:10458909  
PMID:10523647   PMID:10555545   PMID:10617374   PMID:10654608   PMID:10837920   PMID:11042159   PMID:11076861   PMID:11106750   PMID:11217851   PMID:11773602   PMID:12105216   PMID:12220541  
PMID:12376563   PMID:12466851   PMID:12477932   PMID:12894219   PMID:12975469   PMID:14681479   PMID:15029240   PMID:15033999   PMID:15256779   PMID:15489334   PMID:15563473   PMID:15618518  
PMID:15655111   PMID:15782199   PMID:15867431   PMID:16129800   PMID:16141072   PMID:16141073   PMID:16313514   PMID:16702165   PMID:17133482   PMID:17308994   PMID:17419679   PMID:17531086  
PMID:17681951   PMID:18182393   PMID:18240141   PMID:18249171   PMID:18287559   PMID:18323693   PMID:18358244   PMID:18676681   PMID:18799693   PMID:19303854   PMID:19587266   PMID:20211142  
PMID:20232358   PMID:20300111   PMID:21148742   PMID:21267068   PMID:21559334   PMID:21640331   PMID:21873635   PMID:22120177   PMID:22174410   PMID:22974638   PMID:22988430   PMID:22990073  
PMID:23410942   PMID:23475960   PMID:24411941   PMID:24952961   PMID:25649943   PMID:27006338   PMID:30626291   PMID:31578304   PMID:31858519   PMID:32016695   PMID:32815777   PMID:32930455  
PMID:33361391   PMID:34321999   PMID:34335468   PMID:35043944   PMID:35678316  


Genomics

Comparative Map Data
Jund
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39871,150,389 - 71,153,265 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl871,151,599 - 71,153,265 (+)EnsemblGRCm39 Ensembl
GRCm38870,697,739 - 70,700,616 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,698,949 - 70,700,616 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,221,638 - 73,224,515 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,627,938 - 73,629,605 (+)NCBIMGSCv36mm8
Celera873,254,240 - 73,257,113 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
JUND
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,279,694 - 18,281,622 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,279,694 - 18,281,622 (-)EnsemblGRCh38hg38GRCh38
GRCh371918,390,504 - 18,392,432 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,251,570 - 18,253,432 (-)NCBINCBI36Build 36hg18NCBI36
Build 341918,251,569 - 18,253,468NCBI
Celera1918,292,287 - 18,294,173 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1917,954,230 - 17,965,959 (-)NCBIHuRef
CHM1_11918,390,809 - 18,392,678 (-)NCBICHM1_1
T2T-CHM13v2.01918,413,794 - 18,415,722 (-)NCBIT2T-CHM13v2.0
Jund
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,768,093 - 18,769,771 (-)NCBIGRCr8
mRatBN7.21618,734,121 - 18,735,799 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,734,122 - 18,735,799 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,775,785 - 18,777,473 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01619,908,865 - 19,910,549 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,828,735 - 18,830,423 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,485,028 - 20,486,707 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,485,029 - 20,486,707 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,342,096 - 20,343,775 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,239,694 - 19,241,529 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,239,692 - 19,241,527 (-)NCBI
Celera1618,926,295 - 18,927,907 (-)NCBICelera
Cytogenetic Map16p14NCBI
Jund
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555243,176,849 - 3,177,936 (+)NCBIChiLan1.0ChiLan1.0
JUND
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,137,209 - 23,139,083 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,145,537 - 22,147,409 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01917,755,331 - 17,757,164 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,728,466 - 18,729,502 (-)NCBIpanpan1.1PanPan1.1panPan2
JUND
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,737,021 - 44,738,932 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,736,832 - 44,763,020 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,651,244 - 44,653,089 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02045,222,928 - 45,224,778 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2045,222,673 - 45,224,061 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,460,059 - 44,461,903 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,870,705 - 44,872,544 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02045,145,944 - 45,147,789 (+)NCBIUU_Cfam_GSD_1.0
JUND
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1259,530,991 - 59,532,846 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JUND
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1616,754,553 - 16,756,458 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl616,755,247 - 16,756,290 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660742,598,780 - 2,600,647 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Jund
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,573,174 - 1,574,113 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,572,628 - 1,574,205 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Jund
155 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:214
Count of miRNA genes:165
Interacting mature miRNAs:182
Transcripts:ENSMUST00000095267
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3250657271740637Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84809006482090180Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84924559183245673Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
14746987Manh64_mmandible shape 64 (mouse)85050595884505958Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3250657271740637Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined866084397100084549Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84809006482090180Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85474046188740637Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84819016882190288Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85515925889159407Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined871032003105032123Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3250657271740637Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6418673698186736Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86466617698666325Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85050595884505958Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85913640493136404Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85629887290298872Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86872247983326976Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83250657271740637Mouse
11039503Ccc4_mcolitis susceptibility in the Collaborative Cross 4 (mouse)86517423778002730Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86151347995513605Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85233484386334843Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined871032003105032123Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84474791478748059Mouse

Markers in Region
Jund  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38870,699,400 - 70,700,353UniSTSGRCm38
MGSCv37873,223,299 - 73,224,252UniSTSGRCm37
Celera873,255,900 - 73,256,853UniSTS
Cytogenetic Map8C2UniSTS
cM Map833.0UniSTS
Jund1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38870,700,412 - 70,700,598UniSTSGRCm38
MGSCv37873,224,311 - 73,224,497UniSTSGRCm37
Celera873,256,912 - 73,257,095UniSTS
Cytogenetic Map8C2UniSTS
cM Map833.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001286944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA177918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC162446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI844316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE648283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE651959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE995638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ176138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ177858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01070180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD354239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK621709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J04509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J05205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X15358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000095267   ⟹   ENSMUSP00000092901
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl871,151,599 - 71,153,265 (+)Ensembl
GRCm38.p6 Ensembl870,698,949 - 70,700,616 (+)Ensembl
RefSeq Acc Id: NM_001286944   ⟹   NP_001273873
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,150,389 - 71,153,265 (+)NCBI
GRCm38870,697,739 - 70,700,616 (+)NCBI
Celera873,254,240 - 73,257,113 (+)NCBI
Sequence:
RefSeq Acc Id: NM_010592   ⟹   NP_034722
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39871,150,389 - 71,153,265 (+)NCBI
GRCm38870,697,739 - 70,700,616 (+)ENTREZGENE
MGSCv37873,221,638 - 73,224,515 (+)RGD
Celera873,254,240 - 73,257,113 (+)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034722   ⟸   NM_010592
- Peptide Label: isoform JunD-FL
- UniProtKB: P15066 (UniProtKB/Swiss-Prot),   Q52L49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273873   ⟸   NM_001286944
- Peptide Label: isoform deltaJunD
- UniProtKB: Q52L49 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000092901   ⟸   ENSMUST00000095267
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P15066-F1-model_v2 AlphaFold P15066 1-341 view protein structure

Promoters
RGD ID:8667335
Promoter ID:EPDNEW_M11699
Type:multiple initiation site
Name:Jund_1
Description:Mus musculus jun D proto-oncogene , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38870,698,937 - 70,698,997EPDNEW
RGD ID:6843351
Promoter ID:MM_KWN:54728
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_010592
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36873,220,826 - 73,224,507 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96648 AgrOrtholog
Ensembl Genes ENSMUSG00000049389
  ENSMUSG00000071076 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000095267 ENTREZGENE
  ENSMUST00000095267.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AP-1_TF_bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  JNK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leuzip_Jun UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16478 UniProtKB/Swiss-Prot
MGD MGI:96648 ENTREZGENE
NCBI Gene 16478 ENTREZGENE
PANTHER JUN TRANSCRIPTION FACTOR-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11462:SF7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam bZIP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Jun UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Jund PhenoGen
PRINTS LEUZIPPRJUN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47454 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57959 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt JUND_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q52L49 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-26 Jund  jun D proto-oncogene  Jund  Jun proto-oncogene related gene d  Symbol and/or name change 5135510 APPROVED