Akt1 (thymoma viral proto-oncogene 1) - Rat Genome Database

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Gene: Akt1 (thymoma viral proto-oncogene 1) Mus musculus
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Symbol: Akt1
Name: thymoma viral proto-oncogene 1
RGD ID: 735336
MGI Page MGI
Description: Enables protein kinase binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Involved in several processes, including cell surface receptor protein tyrosine kinase signaling pathway; negative regulation of apoptotic signaling pathway; and regulation of gene expression. Acts upstream of or within with a positive effect on gene expression. Acts upstream of or within several processes, including cellular response to cytokine stimulus; embryonic placenta development; and positive regulation of macromolecule metabolic process. Located in several cellular components, including cell-cell junction; microtubule cytoskeleton; and mitochondrion. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; integumental system; and nervous system. Used to study Proteus syndrome and schizophrenia. Human ortholog(s) of this gene implicated in several diseases, including Cowden syndrome 6; breast cancer (multiple); colorectal cancer (multiple); pancreatic cancer (multiple); and reproductive organ cancer (multiple). Orthologous to human AKT1 (AKT serine/threonine kinase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: Ak; Akt; AKT1 kinase; LTR-akt; PK; PKB; PKB alpha; PKB/A; PKB/Akt; PKBalpha; protein kinase B; protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-AKT; Rac; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; related to A and C kinases; tumor rejection antigen peptide pRLib
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912112,620,260 - 112,641,266 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12112,620,255 - 112,641,318 (-)EnsemblGRCm39 Ensembl
GRCm3812112,653,821 - 112,674,884 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12112,653,821 - 112,674,884 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712113,892,032 - 113,912,487 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612113,101,629 - 113,121,998 (-)NCBIMGSCv36mm8
Celera12113,867,449 - 113,888,183 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1261.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model