Elavl1 (ELAV like RNA binding protein 1) - Rat Genome Database

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Gene: Elavl1 (ELAV like RNA binding protein 1) Mus musculus
Analyze
Symbol: Elavl1
Name: ELAV like RNA binding protein 1
RGD ID: 735284
MGI Page MGI
Description: Enables lncRNA binding activity and mRNA 3'-UTR AU-rich region binding activity. Involved in post-transcriptional regulation of gene expression; protein import into nucleus; and regulation of stem cell population maintenance. Acts upstream of or within positive regulation of translation. Located in several cellular components, including cytoplasmic stress granule; endoplasmic reticulum; and sarcoplasm. Part of ribonucleoprotein complex. Is active in cytoplasmic vesicle; glutamatergic synapse; and postsynapse. Is expressed in several structures, including alimentary system; central nervous system; connective tissue; early conceptus; and genitourinary system. Orthologous to human ELAVL1 (ELAV like RNA binding protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2410055N02Rik; ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); elav-like generic protein; ELAV-like protein 1; Hu; HU-antigen A; hu-antigen R; Hua; HUR; melG; W91709
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3984,334,781 - 4,375,104 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl84,335,382 - 4,375,413 (-)EnsemblGRCm39 Ensembl
GRCm3884,284,781 - 4,325,140 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl84,285,382 - 4,325,413 (-)EnsemblGRCm38mm10GRCm38
MGSCv3784,284,782 - 4,325,100 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3684,288,343 - 4,324,906 (-)NCBIMGSCv36mm8
Celera84,485,398 - 4,525,701 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map82.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(Z)-3-butylidenephthalide  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP)
3',5'-cyclic UMP  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-methyladenine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-vinylcyclohexene dioxide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
AICA ribonucleotide  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (ISO)
amsacrine  (ISO)
antimycin A  (ISO)
Aroclor 1254  (EXP)
arsenic trichloride  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (EXP)
copper(II) sulfate  (ISO)
crotonaldehyde  (ISO)
Cuprizon  (ISO)
cycloheximide  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dorsomorphin  (ISO)
enzyme inhibitor  (ISO)
flurbiprofen  (ISO)
folic acid  (EXP)
folpet  (EXP)
formaldehyde  (ISO)
genistein  (ISO)
gentamycin  (ISO)
Goe 6976  (ISO)
hydroquinone  (ISO)
ibuprofen  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
muramyl dipeptide  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-D-aspartic acid  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
ozone  (ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
putrescine  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
rottlerin  (ISO)
SB 431542  (ISO)
sepantronium  (ISO)
sevoflurane  (EXP)
sodium arsenite  (EXP,ISO)
sodium azide  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (EXP)
valproic acid  (ISO)
valsartan  (ISO)
vinclozolin  (ISO)
vorinostat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell physiology  (IAGP)
abnormal blood circulation  (IAGP)
abnormal capillary morphology  (IAGP)
abnormal chorionic plate morphology  (IAGP)
abnormal colon morphology  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal crypts of Lieberkuhn morphology  (IAGP)
abnormal definitive hematopoiesis  (IAGP)
abnormal embryo size  (IEA)
abnormal intestinal epithelium morphology  (IAGP)
abnormal intestinal goblet cell morphology  (IAGP)
abnormal intestinal mucosa morphology  (IAGP)
abnormal limb morphology  (IEA)
abnormal lung development  (IAGP)
abnormal macrophage chemotaxis  (IAGP)
abnormal maternal decidual layer morphology  (IAGP)
abnormal mitochondrial ATP synthesis coupled electron transport  (IAGP)
abnormal muscle contractility  (IAGP)
abnormal myeloid leukocyte morphology  (IAGP)
abnormal negative T cell selection  (IAGP)
abnormal physiological neovascularization  (IAGP)
abnormal placental labyrinth vasculature morphology  (IAGP)
abnormal positive T cell selection  (IAGP)
abnormal skeletal muscle fiber type ratio  (IAGP)
abnormal spleen development  (IAGP)
abnormal spongiotrophoblast cell morphology  (IAGP)
abnormal T cell physiology  (IAGP)
abnormal thymocyte activation  (IAGP)
abnormal vertebrae development  (IAGP)
absent spleen  (IAGP)
anophthalmia  (IEA)
cachexia  (IAGP)
cellular necrosis  (IAGP)
decreased B cell apoptosis  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased CD4-positive, alpha-beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased cell proliferation  (IAGP)
decreased common myeloid progenitor cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased erythroid progenitor cell number  (IAGP)
decreased granulocyte number  (IAGP)
decreased inflammatory response  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased mean corpuscular hemoglobin  (IEA)
decreased spongiotrophoblast size  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased susceptibility to induced muscular atrophy  (IAGP)
decreased T cell proliferation  (IAGP)
decreased T-helper 17 cell number  (IAGP)
decreased trophoblast giant cell number  (IAGP)
delayed endochondral bone ossification  (IAGP)
distended stomach  (IAGP)
edema  (IEA)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enhanced exercise endurance  (IAGP)
impaired pupillary reflex  (IEA)
increased aerobic running capacity  (IAGP)
increased carbon dioxide production  (IAGP)
increased cellular sensitivity to gamma-irradiation  (IAGP)
increased circulating alanine transaminase level  (IEA)
increased circulating interleukin-1 beta level  (IAGP)
increased circulating interleukin-12 level  (IAGP)
increased circulating interleukin-6 level  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased colon adenocarcinoma incidence  (IAGP)
increased colon adenoma incidence  (IAGP)
increased double-negative T cell number  (IAGP)
increased double-positive T cell number  (IAGP)
increased granulocyte number  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased macrophage cell number  (IAGP)
increased monocyte cell number  (IAGP)
increased oxygen consumption  (IAGP)
increased respiratory quotient  (IAGP)
increased single-positive T cell number  (IAGP)
increased susceptibility to endotoxin shock  (IAGP)
increased susceptibility to induced colitis  (IAGP)
increased susceptibility to xenobiotic induced morbidity/mortality  (IAGP)
increased T cell apoptosis  (IAGP)
increased thymocyte number  (IAGP)
increased tumor growth/size  (IAGP)
intestinal obstruction  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lung inflammation  (IAGP)
lymph node hypoplasia  (IAGP)
midline facial cleft  (IAGP)
no abnormal phenotype detected  (IAGP)
pale yolk sac  (IAGP)
placental labyrinth hypoplasia  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
short limbs  (IAGP)
small intestinal villus atrophy  (IAGP)
small limb buds  (IAGP)
small placenta  (IAGP)
spleen hypoplasia  (IAGP)
split xiphoid process  (IAGP)
syndactyly  (IAGP)
synostosis  (IAGP)
thymus hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Postage for the messenger: designating routes for nuclear mRNA export. Natalizio BJ and Wente SR, Trends Cell Biol. 2013 Aug;23(8):365-73. doi: 10.1016/j.tcb.2013.03.006. Epub 2013 Apr 11.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7753842   PMID:9096138   PMID:9344654   PMID:9763509   PMID:10349636   PMID:10721704   PMID:10725249   PMID:11042159   PMID:11076861   PMID:11103939   PMID:12237300   PMID:12477932  
PMID:12520002   PMID:12686504   PMID:12819125   PMID:12832484   PMID:12876290   PMID:12904583   PMID:12944397   PMID:14610273   PMID:14976220   PMID:15020598   PMID:15237213   PMID:15543229  
PMID:15782199   PMID:15878846   PMID:16024790   PMID:16033648   PMID:16141072   PMID:16141073   PMID:16168373   PMID:16602821   PMID:16639702   PMID:16714065   PMID:16982877   PMID:17288565  
PMID:17288991   PMID:17475777   PMID:17531241   PMID:17967808   PMID:17971298   PMID:18273060   PMID:18287559   PMID:18574469   PMID:18678862   PMID:18799693   PMID:19096025   PMID:19289500  
PMID:19307312   PMID:19322201   PMID:19333380   PMID:19334288   PMID:19345675   PMID:19454673   PMID:19501082   PMID:19592461   PMID:19805546   PMID:19884656   PMID:19949288   PMID:20219984  
PMID:20332085   PMID:20351266   PMID:20353946   PMID:20379198   PMID:20584986   PMID:20589882   PMID:20685649   PMID:20963821   PMID:21206905   PMID:21266579   PMID:21267068   PMID:21346194  
PMID:21368052   PMID:21386911   PMID:21402775   PMID:21436445   PMID:21515253   PMID:21613615   PMID:21737689   PMID:21745814   PMID:21795643   PMID:21808035   PMID:22083510   PMID:22095636  
PMID:22201685   PMID:22215620   PMID:22322302   PMID:22371495   PMID:22626558   PMID:22844247   PMID:23056314   PMID:23223443   PMID:23508105   PMID:23516604   PMID:23665500   PMID:23772036  
PMID:23937658   PMID:24005720   PMID:24086407   PMID:24152440   PMID:24166976   PMID:24194600   PMID:24271119   PMID:24362034   PMID:24394384   PMID:24440503   PMID:24457600   PMID:24477678  
PMID:24553115   PMID:24685524   PMID:24687854   PMID:24740539   PMID:25018007   PMID:25085247   PMID:25157170   PMID:25165135   PMID:25301069   PMID:25320093   PMID:25422430   PMID:25533351  
PMID:25588078   PMID:25706746   PMID:25727182   PMID:26162078   PMID:26245959   PMID:26265008   PMID:26336360   PMID:26496610   PMID:26554012   PMID:26601945   PMID:26853752   PMID:26884465  
PMID:27131369   PMID:27383233   PMID:27401462   PMID:27430620   PMID:27609837   PMID:27616329   PMID:27784781   PMID:28031329   PMID:28196122   PMID:28300326   PMID:28350193   PMID:28378742  
PMID:28428272   PMID:28671696   PMID:28684423   PMID:28684740   PMID:28763438   PMID:28982595   PMID:29133460   PMID:29563620   PMID:29674474   PMID:29760195   PMID:29939290   PMID:30081711  
PMID:30333137   PMID:30340104   PMID:30457570   PMID:30498063   PMID:30517011   PMID:30532756   PMID:30668549   PMID:30843060   PMID:31040226   PMID:31077711   PMID:31103627   PMID:31129047  
PMID:31138677   PMID:31147543   PMID:31189591   PMID:31195150   PMID:31373621   PMID:31400163   PMID:31405989   PMID:31495934   PMID:31519904   PMID:31695768   PMID:31801076   PMID:31907992  
PMID:31924774   PMID:31932481   PMID:32075416   PMID:32086392   PMID:32098764   PMID:32169842   PMID:32325033   PMID:32432928   PMID:32434143   PMID:32474254   PMID:32487989   PMID:32546794  
PMID:32713230   PMID:32789690   PMID:32929216   PMID:33047284   PMID:33262333   PMID:33340715   PMID:33346337   PMID:33664225   PMID:33837179   PMID:33855709   PMID:34018851   PMID:34133714  
PMID:34204316   PMID:34395636   PMID:34519101   PMID:34747371   PMID:34772950   PMID:34791230   PMID:34815315   PMID:34862257   PMID:35051552   PMID:35338543   PMID:36214222   PMID:36270801  
PMID:36293380   PMID:36372279   PMID:36438474   PMID:36440604   PMID:36603796   PMID:36629268   PMID:36912171   PMID:37543144   PMID:37697438   PMID:37872163   PMID:38000026   PMID:38355793  
PMID:38369471   PMID:38507413   PMID:38626575   PMID:38663275   PMID:38748875  


Genomics

Comparative Map Data
Elavl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3984,334,781 - 4,375,104 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl84,335,382 - 4,375,413 (-)EnsemblGRCm39 Ensembl
GRCm3884,284,781 - 4,325,140 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl84,285,382 - 4,325,413 (-)EnsemblGRCm38mm10GRCm38
MGSCv3784,284,782 - 4,325,100 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3684,288,343 - 4,324,906 (-)NCBIMGSCv36mm8
Celera84,485,398 - 4,525,701 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map82.0NCBI
ELAVL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38197,958,573 - 8,005,641 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl197,958,573 - 8,005,659 (-)EnsemblGRCh38hg38GRCh38
GRCh37198,023,457 - 8,070,525 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36197,929,457 - 7,976,529 (-)NCBINCBI36Build 36hg18NCBI36
Build 34197,929,457 - 7,976,529NCBI
Celera197,894,704 - 7,941,773 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef197,693,669 - 7,740,685 (-)NCBIHuRef
CHM1_1198,022,943 - 8,069,993 (-)NCBICHM1_1
T2T-CHM13v2.0197,959,562 - 8,006,636 (-)NCBIT2T-CHM13v2.0
Elavl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8127,441,699 - 7,482,625 (-)NCBIGRCr8
mRatBN7.2122,640,936 - 2,684,787 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl122,645,061 - 2,684,784 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx123,291,952 - 3,332,869 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0123,915,541 - 3,956,458 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0122,678,578 - 2,719,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,461,502 - 2,502,432 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,461,502 - 2,502,432 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0124,614,839 - 4,655,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,459,046 - 1,500,042 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1121,458,769 - 1,500,043 (+)NCBI
Celera124,459,379 - 4,500,318 (-)NCBICelera
Cytogenetic Map12p12NCBI
Elavl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555631,283,421 - 1,315,283 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555631,283,424 - 1,315,283 (+)NCBIChiLan1.0ChiLan1.0
ELAVL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22012,645,019 - 12,688,426 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11911,758,555 - 11,805,677 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0197,259,829 - 7,306,808 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1198,114,849 - 8,147,142 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl198,114,849 - 8,147,137 (-)Ensemblpanpan1.1panPan2
ELAVL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12052,648,878 - 52,677,578 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2052,454,132 - 52,491,784 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02053,179,951 - 53,217,640 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2053,180,820 - 53,217,660 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12052,383,218 - 52,420,649 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02052,827,713 - 52,865,411 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02053,059,378 - 53,097,043 (-)NCBIUU_Cfam_GSD_1.0
Elavl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118212,875,753 - 212,906,793 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365884,927,950 - 4,959,064 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365884,931,665 - 4,959,032 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELAVL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl271,207,096 - 71,248,906 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1271,207,141 - 71,245,863 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2271,607,515 - 71,646,238 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ELAVL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.167,419,489 - 7,448,917 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl67,414,757 - 7,448,445 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666081353,624 - 400,190 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elavl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624828914,141 - 948,831 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624828913,001 - 948,826 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Elavl1
1289 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2007
Count of miRNA genes:766
Interacting mature miRNAs:1006
Transcripts:ENSMUST00000098950
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130447432Mouse
13432571Scvg1_msubcutaneous vessel growth QTL 1 (mouse)8124751082Mouse
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131773288Mouse

Markers in Region
RH126821  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3884,288,489 - 4,288,693UniSTSGRCm38
MGSCv3784,288,489 - 4,288,693UniSTSGRCm37
Celera84,489,105 - 4,489,309UniSTS
Cytogenetic Map8A1.1UniSTS
Whitehead/MRC_RH820.62UniSTS
BB284404  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3884,309,961 - 4,310,047UniSTSGRCm38
MGSCv3784,309,961 - 4,310,047UniSTSGRCm37
Celera84,510,562 - 4,510,648UniSTS
Cytogenetic Map8A1.1UniSTS
Whitehead/MRC_RH819.42UniSTS
AI481177  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3884,285,560 - 4,285,647UniSTSGRCm38
MGSCv3784,285,560 - 4,285,647UniSTSGRCm37
Celera84,486,176 - 4,486,263UniSTS
Cytogenetic Map8A1.1UniSTS
Whitehead/MRC_RH820.62UniSTS
Elavl1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3884,288,439 - 4,288,854UniSTSGRCm38
MGSCv3784,288,439 - 4,288,854UniSTSGRCm37
Celera84,489,055 - 4,489,470UniSTS
Cytogenetic Map8A1.1UniSTS
cM Map81.0UniSTS
RH125305  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3884,310,029 - 4,310,131UniSTSGRCm38
MGSCv3784,310,029 - 4,310,131UniSTSGRCm37
Celera84,510,630 - 4,510,732UniSTS
Cytogenetic Map8A1.1UniSTS
UniSTS:225292  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3884,311,388 - 4,311,555UniSTSGRCm38
MGSCv3784,311,388 - 4,311,555UniSTSGRCm37
Celera84,511,989 - 4,512,156UniSTS
Cytogenetic Map8A1.1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006508698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030243302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC155164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK075818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB305633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY775007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U17595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U65735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000098950   ⟹   ENSMUSP00000096549
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl84,335,382 - 4,375,413 (-)Ensembl
GRCm38.p6 Ensembl84,285,382 - 4,325,413 (-)Ensembl
Ensembl Acc Id: ENSMUST00000207615
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl84,360,688 - 4,365,495 (-)Ensembl
GRCm38.p6 Ensembl84,310,688 - 4,315,495 (-)Ensembl
Ensembl Acc Id: ENSMUST00000208987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl84,361,375 - 4,375,086 (-)Ensembl
GRCm38.p6 Ensembl84,311,375 - 4,325,086 (-)Ensembl
Ensembl Acc Id: ENSMUST00000209010   ⟹   ENSMUSP00000146866
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl84,338,343 - 4,362,619 (-)Ensembl
GRCm38.p6 Ensembl84,288,343 - 4,312,619 (-)Ensembl
RefSeq Acc Id: NM_010485   ⟹   NP_034615
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3984,334,782 - 4,375,100 (-)NCBI
GRCm3884,284,782 - 4,325,100 (-)NCBI
MGSCv3784,284,782 - 4,325,100 (-)RGD
Celera84,485,398 - 4,525,701 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006508698   ⟹   XP_006508761
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3984,334,781 - 4,375,104 (-)NCBI
GRCm3884,284,781 - 4,325,140 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243301   ⟹   XP_030099161
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3984,334,781 - 4,371,266 (-)NCBI
GRCm3884,284,781 - 4,321,270 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030243302   ⟹   XP_030099162
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3984,334,781 - 4,375,104 (-)NCBI
GRCm3884,284,781 - 4,325,140 (-)NCBI
Sequence:
RefSeq Acc Id: NP_034615   ⟸   NM_010485
- UniProtKB: Q60745 (UniProtKB/Swiss-Prot),   Q78QY3 (UniProtKB/Swiss-Prot),   P70372 (UniProtKB/Swiss-Prot),   Q3UFF9 (UniProtKB/TrEMBL),   Q8BM84 (UniProtKB/TrEMBL),   Q8BW03 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006508761   ⟸   XM_006508698
- Peptide Label: isoform X1
- UniProtKB: Q60745 (UniProtKB/Swiss-Prot),   Q78QY3 (UniProtKB/Swiss-Prot),   P70372 (UniProtKB/Swiss-Prot),   Q3UFF9 (UniProtKB/TrEMBL),   Q8BM84 (UniProtKB/TrEMBL),   Q8BW03 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030099162   ⟸   XM_030243302
- Peptide Label: isoform X1
- UniProtKB: Q60745 (UniProtKB/Swiss-Prot),   P70372 (UniProtKB/Swiss-Prot),   Q78QY3 (UniProtKB/Swiss-Prot),   Q3UFF9 (UniProtKB/TrEMBL),   Q8BM84 (UniProtKB/TrEMBL),   Q8BW03 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030099161   ⟸   XM_030243301
- Peptide Label: isoform X1
- UniProtKB: Q60745 (UniProtKB/Swiss-Prot),   P70372 (UniProtKB/Swiss-Prot),   Q78QY3 (UniProtKB/Swiss-Prot),   Q3UFF9 (UniProtKB/TrEMBL),   Q8BM84 (UniProtKB/TrEMBL),   Q8BW03 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000096549   ⟸   ENSMUST00000098950
Ensembl Acc Id: ENSMUSP00000146866   ⟸   ENSMUST00000209010
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70372-F1-model_v2 AlphaFold P70372 1-326 view protein structure

Promoters
RGD ID:6843009
Promoter ID:MM_KWN:53542
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000098949,   ENSMUST00000116496,   LINCRNA_976,   NM_010485,   OTTMUST00000053636,   OTTMUST00000053637,   OTTMUST00000053641,   UC009KTT.1,   UC009KTU.1,   UC009KTV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3684,325,001 - 4,325,501 (+)MPROMDB
RGD ID:8666385
Promoter ID:EPDNEW_M11224
Type:initiation region
Name:Elavl1_1
Description:Mus musculus ELAV (embryonic lethal, abnormal vision)-like 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3884,325,061 - 4,325,121EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1100851 AgrOrtholog
Ensembl Genes ENSMUSG00000040028 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000098950 ENTREZGENE
  ENSMUST00000098950.6 UniProtKB/Swiss-Prot
  ENSMUST00000209010 ENTREZGENE
  ENSMUST00000209010.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ELAD_HU_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hud_Sxl_RNA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HuR_RRM2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15568 UniProtKB/Swiss-Prot
MGD MGI:1100851 ENTREZGENE
NCBI Gene 15568 ENTREZGENE
PANTHER ELAV-LIKE PROTEIN 1 UniProtKB/TrEMBL
  EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Elavl1 PhenoGen
PRINTS HUDSXLRNA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ELAV1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TT05_MOUSE UniProtKB/TrEMBL
  Q3UFF9 ENTREZGENE, UniProtKB/TrEMBL
  Q60745 ENTREZGENE
  Q78QY3 ENTREZGENE
  Q8BM84 ENTREZGENE, UniProtKB/TrEMBL
  Q8BTQ1_MOUSE UniProtKB/TrEMBL
  Q8BVF8_MOUSE UniProtKB/TrEMBL
  Q8BW03 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q60745 UniProtKB/Swiss-Prot
  Q78QY3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Elavl1  ELAV like RNA binding protein 1  Elavl1  ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)  Symbol and/or name change 5135510 APPROVED
2012-07-05 Elavl1  ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)  Elavl1  ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)  Symbol and/or name change 5135510 APPROVED