Rps6 (ribosomal protein S6) - Rat Genome Database

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Gene: Rps6 (ribosomal protein S6) Mus musculus
Analyze
Symbol: Rps6
Name: ribosomal protein S6
RGD ID: 735280
MGI Page MGI
Description: A structural constituent of ribosome. Involved in glucose homeostasis. Acts upstream of or within several processes, including G1/S transition of mitotic cell cycle; T cell activation; and ribosome biogenesis. Located in dendrite; perinuclear region of cytoplasm; and ribosome. Part of cytosolic small ribosomal subunit. Is expressed in several structures, including alimentary system; brain; gonad; hemolymphoid system gland; and limb. Orthologous to human RPS6 (ribosomal protein S6).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 40S ribosomal protein S6; MGC102571; MGC103209; phosphoprotein NP33; S; S6R; small ribosomal subunit protein eS6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: BC023719   Gm11263   Gm11604   Gm11622   Gm11903   Gm11919   Gm12149   Gm12242   Gm12370   Gm12383   Gm13495   Gm13593   Gm14083   Gm14138   Gm14172   Gm14987   Gm15388   Gm16409   Gm17952   Gm17953   Gm17955   Gm17972   Gm17974   Gm18006   Gm18010   Gm18020   Gm18026   Gm18027   Gm18028   Gm18039   Gm18041   Gm18043   Gm18068   Gm18070   Gm18071   Gm18089   Gm18094   Gm2860   Gm3040   Gm6476   Gm8145   Gm8172   Rps6-ps1   Rps6-ps2   Rps6-ps3   Rps6-ps4  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39486,772,336 - 86,775,604 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl486,772,897 - 86,775,649 (-)EnsemblGRCm39 Ensembl
GRCm38486,854,099 - 86,857,367 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl486,854,660 - 86,857,412 (-)EnsemblGRCm38mm10GRCm38
MGSCv37486,500,003 - 86,503,271 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36486,325,893 - 86,328,588 (-)NCBIMGSCv36mm8
Celera485,374,929 - 85,378,195 (-)NCBICelera
Cytogenetic Map4C4NCBI
cM Map440.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (ISO)
(+)-Tetrandrine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-nicotine  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-deoxy-D-glucose  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3'-diindolylmethane  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5'-S-methyl-5'-thioadenosine  (ISO)
5-azacytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
acetylsalicylic acid  (ISO)
AICA ribonucleotide  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
alpha-Zearalanol  (ISO)
Alpinetin  (EXP,ISO)
amino acid  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amosite asbestos  (ISO)
amphibole asbestos  (ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (ISO)
artesunate  (ISO)
avobenzone  (ISO)
AZD4547  (ISO)
azoxystrobin  (ISO)
Bardoxolone methyl  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP)
berberine  (ISO)
beta-D-glucosamine  (ISO)
Betanin  (ISO)
bicalutamide  (ISO)
biguanides  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bortezomib  (EXP)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calciol  (ISO)
calyculin a  (ISO)
camostat  (EXP)
camptothecin  (EXP)
cannabidiol  (ISO)
capivasertib  (ISO)
carbon nanotube  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
cholesterol  (EXP,ISO)
choline  (EXP)
chromium(6+)  (EXP)
chrysophanol  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
cobimetinib  (ISO)
corosolic acid  (ISO)
coumarin  (ISO)
crizotinib  (ISO)
crocidolite asbestos  (EXP)
Cuprizon  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (EXP)
D-glucose  (ISO)
dactolisib  (ISO)
deguelin  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dibutylstannane  (ISO)
dicrotophos  (ISO)
dihydroartemisinin  (ISO)
dimethyl sulfoxide  (EXP,ISO)
Dinitramine  (EXP)
dioxygen  (ISO)
dodecanoic acid  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzacamene  (ISO)
enzyme inhibitor  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (EXP,ISO)
etoposide  (ISO)
everolimus  (ISO)
fenthion  (EXP)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
FR900359  (ISO)
genistein  (EXP)
gentamycin  (ISO)
Gingerenone A  (EXP,ISO)
ginsenoside Rg1  (ISO)
glucose  (ISO)
glutathione  (ISO)
hexadecanoic acid  (ISO)
indometacin  (ISO)
isoflurane  (ISO)
ivermectin  (ISO)
Ku-0063794  (ISO)
L-ethionine  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
letrozole  (ISO)
lipopolysaccharide  (ISO)
lonidamine  (ISO)
loratadine  (ISO)
LY294002  (EXP,ISO)
mechlorethamine  (EXP,ISO)
metformin  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
miconazole  (EXP)
microcystin-LR  (ISO)
MK-2206  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (EXP)
monocrotaline  (ISO)
mycophenolic acid  (ISO)
N(6)-butyryl-cAMP  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
niclosamide  (ISO)
nicotinamide  (ISO)
nicotine  (EXP)
nitric oxide  (EXP)
ochratoxin A  (ISO)
omeprazole  (ISO)
omipalisib  (ISO)
orlistat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PD 0325901  (ISO)
pentachlorophenol  (ISO)
pentetrazol  (ISO)
perfluorooctanoic acid  (ISO)
PHA-665752  (ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
picoxystrobin  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (EXP)
propiconazole  (EXP)
prostaglandin E2  (ISO)
pyrvinium  (EXP,ISO)
quercetin  (EXP,ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
rimonabant  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
sapanisertib  (EXP)
SB 431542  (ISO)
simvastatin  (EXP)
sirolimus  (EXP,ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
sorafenib  (ISO)
sotorasib  (ISO)
sulforaphane  (ISO)
sulprostone  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (EXP)
tanespimycin  (ISO)
Temsirolimus  (ISO)
Terfenadine  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
thiram  (ISO)
topiramate  (ISO)
torin 1  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (EXP)
triptonide  (EXP)
tungsten  (EXP)
vandetanib  (ISO)
vorinostat  (ISO)
wortmannin  (ISO)
zearalenone  (EXP)
zinc pyrithione  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury. Chuang YC, etal., Int J Mol Sci. 2015 Nov 4;16(11):26406-16. doi: 10.3390/ijms161125963.
3. Proteomic and biochemical analyses reveal the activation of unfolded protein response, ERK-1/2 and ribosomal protein S6 signaling in experimental autoimmune myocarditis rat model. Chung JH, etal., BMC Genomics. 2011 Oct 20;12:520. doi: 10.1186/1471-2164-12-520.
4. Two-dimensional electrophoretic analysis of ribosomal proteins from chronically injured liver. Gressner AM J Clin Chem Clin Biochem. 1979 Aug;17(8):541-5.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
7. The mammalian RPS6 gene, homolog of the Drosophila air8 tumor suppressor gene: is it an oncosuppressor gene? Lecomte F, etal., Somat Cell Mol Genet 1995 Nov;21(6):443-50.
8. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. MGD IEA MGD IEA
11. Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. O'Donohue MF, etal., J Cell Biol. 2010 Sep 6;190(5):853-66. doi: 10.1083/jcb.201005117.
12. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
13. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
14. Mouse MP Annotation Import Pipeline RGD automated import pipeline
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint. Yang H, etal., Autophagy. 2020 Feb;16(2):271-288. doi: 10.1080/15548627.2019.1606647. Epub 2019 Apr 21.
17. Effects of electroacupuncture on the expression of p70 ribosomal protein S6 kinase and ribosomal protein S6 in the hippocampus of rats with vascular dementia. Zhu Y, etal., Neural Regen Res. 2012 Jan 25;7(3):207-11. doi: 10.3969/j.issn.1673-5374.2012.03.009.
Additional References at PubMed
PMID:1939282   PMID:3601662   PMID:8440735   PMID:8917105   PMID:10349636   PMID:10856218   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12388085   PMID:12477932   PMID:14610273  
PMID:14681305   PMID:14993219   PMID:15010863   PMID:15489334   PMID:15939374   PMID:16141072   PMID:16141073   PMID:16166381   PMID:16286931   PMID:16357222   PMID:16452087   PMID:16537919  
PMID:16602821   PMID:17000767   PMID:17245776   PMID:17726024   PMID:18362888   PMID:18371380   PMID:18468454   PMID:18495661   PMID:18599511   PMID:18641651   PMID:18799693   PMID:18809582  
PMID:18851840   PMID:18988856   PMID:19047368   PMID:19114715   PMID:19141683   PMID:19273598   PMID:19287375   PMID:19357198   PMID:19463158   PMID:19470613   PMID:19479038   PMID:19635472  
PMID:19808022   PMID:19843504   PMID:19850877   PMID:19917692   PMID:20227039   PMID:20399730   PMID:20457809   PMID:20625781   PMID:20925120   PMID:21045808   PMID:21238928   PMID:21321084  
PMID:21529712   PMID:21565611   PMID:21765940   PMID:21788341   PMID:22022532   PMID:22056141   PMID:22094257   PMID:22198155   PMID:22725947   PMID:22794259   PMID:22798074   PMID:22984623  
PMID:23053848   PMID:23071096   PMID:23100423   PMID:23136395   PMID:23255058   PMID:23318442   PMID:23361300   PMID:23372768   PMID:23500592   PMID:23637172   PMID:23744272   PMID:23789091  
PMID:24129405   PMID:24218567   PMID:24457600   PMID:24497849   PMID:24552588   PMID:24557881   PMID:24610119   PMID:24700326   PMID:24857653   PMID:24874427   PMID:24948603   PMID:25145583  
PMID:25179606   PMID:25229342   PMID:25273085   PMID:25535838   PMID:25568082   PMID:25574476   PMID:25617592   PMID:25670795   PMID:25838128   PMID:25901680   PMID:25922525   PMID:26075820  
PMID:26120033   PMID:26178919   PMID:26235615   PMID:26283674   PMID:26296742   PMID:26336360   PMID:26383973   PMID:26410627   PMID:26449264   PMID:26633882   PMID:26809587   PMID:26919188  
PMID:27802136   PMID:27807348   PMID:27993979   PMID:28069738   PMID:28119058   PMID:28162974   PMID:28170423   PMID:28250050   PMID:28341395   PMID:28341829   PMID:28378742   PMID:28542142  
PMID:28880149   PMID:28934393   PMID:28974734   PMID:29117561   PMID:29311811   PMID:29518331   PMID:29950673   PMID:30050055   PMID:30081710   PMID:30449657   PMID:30550785   PMID:30595499  
PMID:30799239   PMID:30872276   PMID:30893610   PMID:31064784   PMID:31162944   PMID:31285269   PMID:31345937   PMID:31607856   PMID:31789450   PMID:32043969   PMID:32113911   PMID:32115408  
PMID:32325033   PMID:32350925   PMID:32385093   PMID:32392211   PMID:32457579   PMID:32550912   PMID:32554809   PMID:32747435   PMID:32853550   PMID:32856318   PMID:33052068   PMID:33100228  
PMID:33436499   PMID:33462112   PMID:33470495   PMID:34070742   PMID:34148274   PMID:34157307   PMID:34193412   PMID:34242585   PMID:34344824   PMID:34381067   PMID:34395439   PMID:34401671  
PMID:34677125   PMID:34685710   PMID:34999833   PMID:35022234   PMID:35341793   PMID:35499085   PMID:35645731   PMID:35778392   PMID:35858542   PMID:36114006   PMID:36198274   PMID:36353506  
PMID:36417873   PMID:36433959   PMID:36440598   PMID:36509146   PMID:36517592   PMID:36528027   PMID:36627370   PMID:36656901   PMID:36680774   PMID:36693323   PMID:36822087   PMID:36982451  
PMID:36996814   PMID:37036444   PMID:37068088   PMID:37098351   PMID:37704377   PMID:37812701   PMID:38272677   PMID:38466355  


Genomics

Comparative Map Data
Rps6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39486,772,336 - 86,775,604 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl486,772,897 - 86,775,649 (-)EnsemblGRCm39 Ensembl
GRCm38486,854,099 - 86,857,367 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl486,854,660 - 86,857,412 (-)EnsemblGRCm38mm10GRCm38
MGSCv37486,500,003 - 86,503,271 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36486,325,893 - 86,328,588 (-)NCBIMGSCv36mm8
Celera485,374,929 - 85,378,195 (-)NCBICelera
Cytogenetic Map4C4NCBI
cM Map440.69NCBI
RPS6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38919,375,715 - 19,380,236 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl919,375,715 - 19,380,236 (-)EnsemblGRCh38hg38GRCh38
GRCh37919,375,713 - 19,380,234 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36919,366,254 - 19,370,235 (-)NCBINCBI36Build 36hg18NCBI36
Build 34919,366,253 - 19,370,235NCBI
Celera919,302,350 - 19,306,331 (-)NCBICelera
Cytogenetic Map9p22.1NCBI
HuRef919,337,814 - 19,341,795 (-)NCBIHuRef
CHM1_1919,376,051 - 19,380,032 (-)NCBICHM1_1
T2T-CHM13v2.0919,388,517 - 19,393,023 (-)NCBIT2T-CHM13v2.0
Rps6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85106,417,680 - 106,420,540 (-)NCBIGRCr8
mRatBN7.25101,371,716 - 101,374,576 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl566,681,075 - 66,681,919 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl5101,371,136 - 101,374,602 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5103,752,605 - 103,755,465 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05105,543,160 - 105,546,020 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05105,576,526 - 105,579,388 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05105,197,821 - 105,200,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,197,857 - 105,200,148 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,209,846 - 105,212,173 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05109,184,689 - 109,187,549 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45106,165,612 - 106,168,472 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5101,709,190 - 101,712,050 (+)NCBICelera
Cytogenetic Map5q32NCBI
Rps6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543421,744,082 - 21,746,626 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543421,744,045 - 21,745,646 (-)NCBIChiLan1.0ChiLan1.0
RPS6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211105,135,133 - 105,170,654 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19105,141,077 - 105,176,598 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0919,185,455 - 19,189,504 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1919,674,380 - 19,678,397 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl919,674,380 - 19,677,722 (-)Ensemblpanpan1.1panPan2
RPS6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11139,161,422 - 39,165,148 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1139,161,422 - 39,165,148 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1137,819,139 - 37,822,865 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01140,094,843 - 40,098,569 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1140,094,843 - 40,098,569 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11138,787,210 - 38,790,959 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01138,584,732 - 38,588,458 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01139,218,708 - 39,222,435 (-)NCBIUU_Cfam_GSD_1.0
Rps6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947153,583,479 - 153,586,550 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366521,253,025 - 1,255,906 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366521,252,986 - 1,255,987 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1203,444,450 - 203,451,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11203,444,360 - 203,447,643 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,094,866 - 227,098,139 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPS6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11260,353,800 - 60,357,797 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1260,353,817 - 60,357,759 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603848,467,090 - 48,471,105 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473623,328,002 - 23,336,140 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473623,332,556 - 23,336,234 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rps6
116 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:384
Count of miRNA genes:306
Interacting mature miRNAs:336
Transcripts:ENSMUST00000102814, ENSMUST00000123229, ENSMUST00000130001, ENSMUST00000136174
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123127211Mouse
13506251Cytrq1_mcytokine response QTL 1 (mouse)46571808699718086Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
1357726Lnopy1_mlens opacity 1 (mouse)Not determined485428838119429037Mouse
11532708Sluc43i_msusceptibility to lung cancer 43i (mouse)474444699108444983Mouse
11532707Sluc43h_msusceptibility to lung cancer 43h (mouse)474444699108444983Mouse
11532706Sluc43c_msusceptibility to lung cancer 43c (mouse)474444699108444983Mouse
11532705Sluc43b_msusceptibility to lung cancer 43b (mouse)474444699108444983Mouse
10412176Habiir3_mhyperoxic acute lung injury imprinted region 3 (mouse)Not determined48375713094293740Mouse
1302044Nss1_mNOD Sjogren's syndrome 1 (mouse)Not determined471982069105982216Mouse
11532704Sluc43a_msusceptibility to lung cancer 43a (mouse)474444699108444983Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
1302031Bulb1_mbulb size 1 (mouse)Not determined474033887108034029Mouse
27095939Ulnl9_mulna length 9, 16 week (mouse)465318237118857197Mouse
27095938Ulnl6_mulna length 6, 10 week (mouse)46671823798588237Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
12904933Edlmmq3_mextensor digitorum longus muscle mass QTL 3 (mouse)481213991115213991Mouse
10043964Obq26_mobesity QTL 26 (mouse)Not determined45904725193047251Mouse
13524841Hbasrq1_mhabituation of the acoustic startle response QTL 1 (mouse)45447158988471589Mouse
1301556Cd4vts1_mCD4 virgin T cell subset 1 (mouse)Not determined485428838119429037Mouse
13524838Hbasrq1a_mhabituation of the acoustic startle response QTL 1a (mouse)45447158988471589Mouse
26884406Huml3_mhumerus length 3, 10 week (mouse)475618237100157197Mouse
1302204Spm1_msplenomegaly modifier (mouse)Not determined482244395116244582Mouse
11532703Sluc43g_msusceptibility to lung cancer 43g (mouse)474444699108444983Mouse
11532702Sluc43f_msusceptibility to lung cancer 43f (mouse)474444699108444983Mouse
11532701Sluc43e_msusceptibility to lung cancer 43e (mouse)474444699108444983Mouse
1558948Ath8_matherosclerosis 8 (mouse)Not determined445658442105156995Mouse
11532700Sluc43d_msusceptibility to lung cancer 43d (mouse)474444699108444983Mouse
11039517Ltpr4_mLeishmania tropica response 4 (mouse)479365751113365867Mouse
11039504Ltpr4a_mLeishmania tropica response 4a (mouse)479365751113365867Mouse
11039505Ltpr4c_mLeishmania tropica response 4c (mouse)479365751113365867Mouse
1301930Papg1_mpulmonary adenoma progression 1 (mouse)Not determined485781167119781279Mouse
1301033Abbp2_mA/J and C57BL/6 blood pressure 2 (mouse)Not determined45355083993763305Mouse
1357870Pfat1_mpredicted fat percentage 1 (mouse)Not determined46361952697619685Mouse
1302057Pgia27_mproteoglycan induced arthritis 27 (mouse)Not determined470067227104067464Mouse
1301545Gauc_mglucose area under curve (mouse)Not determined476763107110763305Mouse
11039506Ltpr4b_mLeishmania tropica response 4b (mouse)479365751113365867Mouse
27226787Feml14_mfemur length 14, 10 week (mouse)484918237107157197Mouse
10412193Plep_mplasma lepin levels (mouse)Not determined474444699108444983Mouse
27095900Scvln9_msacral vertebrae length 2, 10 week (mouse)468018237107157197Mouse
4142203Lyr_mlymphoma resistance (mouse)Not determined8075244588769188Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
26884434Zlq1_mzygomatic length QTL 1, 5 week (mouse)453700000103257197Mouse
26884435Zlq4_mzygomatic length QTL 4, 10 week (mouse)485118237104957197Mouse
1300697Sle2_msystemic lupus erythmatosus susceptibility 2 (mouse)Not determined477957579111957775Mouse
1301597Anxty_manxiety (mouse)Not determined474137574128009280Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
12880404Embq1_memotional behavior QTL 1 (mouse)46575720395921546Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
1301190Cd4ts2_mCD4 T cell subset 2 (mouse)Not determined46014527794145424Mouse
26884431Zlq8_mzygomatic length QTL 8, 16 week (mouse)474718237108357197Mouse
1357507Synch2_msynechia 2 (mouse)Not determined46014527794145424Mouse
12879903Berr8_mberghei resistance locus 8 (mouse)46422246098222460Mouse
13207572Spir2_mStreptococcus pneumoniae infection resistance 2 (mouse)45068279588510637Mouse
12879897Berr4_mberghei resistance locus 4 (mouse)471982069105982216Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
27095934Ulnl2_mulna length 2, 5 week (mouse)45770000094788237Mouse
12904738Idohtq_miris defect with ocular hypertension QTL (mouse)48075246793112991Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
27095924Pglq2_mpelvic girdle length QTL 2, 5 week (mouse)469118237130727311Mouse
27095921Pglq12_mpelvic girdle length QTL 12, 16 week (mouse)483118237108357197Mouse
1357561Mbsyd_mmetabolic syndrome (mouse)Not determined466888445100888588Mouse
1301118Bbaa23_mB.burgdorferi-associated arthritis 23 (mouse)Not determined485781167119781279Mouse
1301757Tlsr4_mthymic lymphoma suppressor region 4 (mouse)Not determined466757130100757258Mouse
27095917Scvln14_msacral vertebrae length 2, 16 week (mouse)468018237130277062Mouse
4141900Skts-fp1_mskin tumor susceptibility in FVB and PWK 1 (mouse)Not determined453550839124055180Mouse
1300966Pabr2_mplasma apolipoprotein B (human) regulator 2 (mouse)Not determined446332646105801860Mouse
1301739Pitm2_mprion incubation time 2 (mouse)Not determined471982069105982216Mouse
1301867Idd11_minsulin dependent diabetes susceptibility 11 (mouse)Not determined483604870117605006Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108357197Mouse
27095905Scvln3_msacral vertebrae length 2, 5 week (mouse)455600000128993793Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK012284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC090392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX005084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X89040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y00348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z54209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: NM_009096   ⟹   NP_033122
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39486,772,336 - 86,775,604 (-)NCBI
GRCm38486,854,099 - 86,857,367 (-)ENTREZGENE
MGSCv37486,500,003 - 86,503,271 (-)RGD
Celera485,374,929 - 85,378,195 (-)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033122   ⟸   NM_009096
- UniProtKB: P62754 (UniProtKB/Swiss-Prot),   Q5BLK1 (UniProtKB/TrEMBL),   Q3TL53 (UniProtKB/TrEMBL)
- Sequence:

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62754-F1-model_v2 AlphaFold P62754 1-249 view protein structure

Promoters
RGD ID:6836327
Promoter ID:MM_KWN:38286
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000017760,   OTTMUST00000017761,   OTTMUST00000017762,   OTTMUST00000017763
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36486,503,096 - 86,503,596 (-)MPROMDB
RGD ID:6883778
Promoter ID:EPDNEW_M5340
Type:initiation region
Name:Rps6_1
Description:Mus musculus ribosomal protein S6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38486,857,368 - 86,857,428EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98159 AgrOrtholog
Ensembl Genes ENSMUSG00000028495 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000102814 ENTREZGENE
  ENSMUST00000102814.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.2650 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ribosomal_S6_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S6e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S6e_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20104 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98159 ENTREZGENE
NCBI Gene 20104 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11502 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_S6e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rps6 PhenoGen
PIRSF Ribosom_S6_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RIBOSOMAL_S6E UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Ribosomal_S6e UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P62754 ENTREZGENE
  Q3TL53 ENTREZGENE, UniProtKB/TrEMBL
  Q5BLK1 ENTREZGENE, UniProtKB/TrEMBL
  Q8BT09_MOUSE UniProtKB/TrEMBL
  RS6_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary P08227 UniProtKB/Swiss-Prot
  P10660 UniProtKB/Swiss-Prot