Sil1 (SIL1 nucleotide exchange factor) - Rat Genome Database

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Gene: Sil1 (SIL1 nucleotide exchange factor) Rattus norvegicus
Analyze
Symbol: Sil1
Name: SIL1 nucleotide exchange factor
RGD ID: 735103
Description: Predicted to enable adenyl-nucleotide exchange factor activity and identical protein binding activity. Predicted to be involved in protein transport. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in primary cerebellar degeneration. Orthologous to human SIL1 (SIL1 nucleotide exchange factor); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,5-hexanedione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae); MGC72590; nucleotide exchange factor SIL1; SIL1 homolog, endoplasmic reticulum chaperone; SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae); similar to endoplasmic reticulum chaperone SIL1 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,146,526 - 27,378,459 (-)NCBIGRCr8
mRatBN7.21826,872,423 - 27,104,365 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1826,872,429 - 27,104,332 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1826,999,821 - 27,231,724 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01827,762,741 - 27,994,497 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01827,097,649 - 27,329,387 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01828,067,476 - 28,302,008 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,067,484 - 28,301,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01827,777,570 - 28,015,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,780,878 - 27,957,033 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11827,807,524 - 27,983,675 (-)NCBI
Celera1826,607,704 - 26,838,633 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. BAP, a mammalian BiP-associated protein, is a nucleotide exchange factor that regulates the ATPase activity of BiP. Chung KT, etal., J Biol Chem 2002 Dec 6;277(49):47557-63. Epub 2002 Sep 27.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:16116427   PMID:16502470  


Genomics

Comparative Map Data
Sil1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81827,146,526 - 27,378,459 (-)NCBIGRCr8
mRatBN7.21826,872,423 - 27,104,365 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1826,872,429 - 27,104,332 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1826,999,821 - 27,231,724 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01827,762,741 - 27,994,497 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01827,097,649 - 27,329,387 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01828,067,476 - 28,302,008 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1828,067,484 - 28,301,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01827,777,570 - 28,015,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41827,780,878 - 27,957,033 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11827,807,524 - 27,983,675 (-)NCBI
Celera1826,607,704 - 26,838,633 (-)NCBICelera
Cytogenetic Map18p11NCBI
SIL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385138,946,724 - 139,198,368 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5138,946,724 - 139,293,557 (-)EnsemblGRCh38hg38GRCh38
GRCh375138,282,413 - 138,534,057 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365138,310,308 - 138,561,964 (-)NCBINCBI36Build 36hg18NCBI36
Celera5134,404,181 - 134,655,785 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5133,472,204 - 133,723,612 (-)NCBIHuRef
CHM1_15137,714,967 - 137,966,619 (-)NCBICHM1_1
T2T-CHM13v2.05139,472,860 - 139,724,442 (-)NCBIT2T-CHM13v2.0
Sil1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391835,399,449 - 35,632,443 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1835,399,449 - 35,632,833 (-)EnsemblGRCm39 Ensembl
GRCm381835,266,396 - 35,499,390 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1835,266,396 - 35,499,780 (-)EnsemblGRCm38mm10GRCm38
MGSCv371835,426,050 - 35,658,579 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361835,392,370 - 35,624,840 (-)NCBIMGSCv36mm8
Celera1835,722,030 - 35,955,224 (-)NCBICelera
Cytogenetic Map18B1- B2NCBI
cM Map1818.97NCBI
Sil1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554181,392,985 - 1,583,376 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554181,322,644 - 1,583,352 (+)NCBIChiLan1.0ChiLan1.0
SIL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24134,221,096 - 134,469,295 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15132,360,647 - 132,608,705 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05134,325,451 - 134,573,398 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15140,450,758 - 140,696,688 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5140,450,891 - 140,628,703 (-)Ensemblpanpan1.1panPan2
SIL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11126,470,439 - 26,689,198 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1126,470,487 - 26,731,294 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1125,237,309 - 25,456,067 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01127,326,034 - 27,544,943 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1127,321,759 - 27,594,868 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11126,033,324 - 26,252,680 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01125,855,663 - 26,074,458 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01126,520,214 - 26,739,659 (-)NCBIUU_Cfam_GSD_1.0
Sil1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213153,291,212 - 153,549,064 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365318,060,787 - 8,320,302 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365318,062,441 - 8,320,287 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2140,878,070 - 141,118,059 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12140,884,170 - 141,118,201 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SIL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12341,611,360 - 41,855,632 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2341,609,484 - 41,855,663 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603436,035,024 - 36,272,681 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sil1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474331,708,423 - 31,935,257 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474331,709,989 - 32,015,770 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sil1
624 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:157
Count of miRNA genes:126
Interacting mature miRNAs:132
Transcripts:ENSRNOT00000026895
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181194179131393320Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194429931359530Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181823456431359530Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat

Markers in Region
D18Rat68  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21826,968,422 - 26,968,532 (+)MAPPERmRatBN7.2
Rnor_6.01828,163,255 - 28,163,364NCBIRnor6.0
Rnor_5.01827,877,050 - 27,877,159UniSTSRnor5.0
RGSC_v3.41827,877,518 - 27,877,816RGDRGSC3.4
RGSC_v3.41827,877,706 - 27,877,815UniSTSRGSC3.4
RGSC_v3.11827,904,352 - 27,904,461RGD
Celera1826,703,038 - 26,703,147UniSTS
RH 3.4 Map18374.9RGD
RH 3.4 Map18374.9UniSTS
RH 2.0 Map18535.3RGD
FHH x ACI Map1817.18RGD
Cytogenetic Map18p11UniSTS
D18Chm5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21827,056,864 - 27,057,108 (+)MAPPERmRatBN7.2
Rnor_6.01828,251,694 - 28,251,935NCBIRnor6.0
Rnor_5.01827,965,437 - 27,965,678UniSTSRnor5.0
RGSC_v3.41827,966,059 - 27,966,300UniSTSRGSC3.4
Celera1826,791,461 - 26,791,702UniSTS
Cytogenetic Map18p11UniSTS
RH129926  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21826,872,430 - 26,872,644 (+)MAPPERmRatBN7.2
Rnor_6.01828,067,485 - 28,067,698NCBIRnor6.0
Rnor_5.01827,777,579 - 27,777,792UniSTSRnor5.0
RGSC_v3.41827,780,880 - 27,781,093UniSTSRGSC3.4
Celera1826,607,706 - 26,607,919UniSTS
RH 3.4 Map18374.8UniSTS
Cytogenetic Map18p11UniSTS
BI289115  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21826,897,708 - 26,897,951 (+)MAPPERmRatBN7.2
Rnor_6.01828,092,519 - 28,092,761NCBIRnor6.0
Rnor_5.01827,802,254 - 27,802,496UniSTSRnor5.0
RGSC_v3.41827,805,815 - 27,806,057UniSTSRGSC3.4
Celera1826,632,510 - 26,632,752UniSTS
RH 3.4 Map18374.8UniSTS
Cytogenetic Map18p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 18 57 41 19 41 1 39 35 39 11
Low 25 8 10 35 2 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000026895   ⟹   ENSRNOP00000026895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,872,429 - 27,104,332 (-)Ensembl
Rnor_6.0 Ensembl1828,067,484 - 28,301,863 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102716   ⟹   ENSRNOP00000097662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,872,429 - 27,033,678 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104681   ⟹   ENSRNOP00000078831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,872,432 - 27,015,859 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105808   ⟹   ENSRNOP00000081504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,872,429 - 27,047,824 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107530   ⟹   ENSRNOP00000097578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1826,872,429 - 27,051,423 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113606   ⟹   ENSRNOP00000076899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1827,043,080 - 27,047,824 (-)Ensembl
RefSeq Acc Id: NM_199376   ⟹   NP_955408
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,146,526 - 27,378,398 (-)NCBI
mRatBN7.21826,872,429 - 27,104,302 (-)NCBI
Rnor_6.01828,067,483 - 28,301,863 (-)NCBI
Rnor_5.01827,777,570 - 28,015,033 (-)NCBI
RGSC_v3.41827,780,878 - 27,957,033 (-)RGD
Celera1826,607,704 - 26,838,633 (-)RGD
Sequence:
RefSeq Acc Id: XM_008772025   ⟹   XP_008770247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,146,526 - 27,378,459 (-)NCBI
mRatBN7.21826,872,427 - 27,104,365 (-)NCBI
Rnor_6.01828,067,476 - 28,301,962 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600905   ⟹   XP_017456394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,146,526 - 27,362,919 (-)NCBI
mRatBN7.21826,872,427 - 27,088,836 (-)NCBI
Rnor_6.01828,067,476 - 28,288,395 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039096718   ⟹   XP_038952646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,146,526 - 27,356,854 (-)NCBI
mRatBN7.21826,872,427 - 27,082,564 (-)NCBI
RefSeq Acc Id: XM_039096720   ⟹   XP_038952648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,146,526 - 27,321,908 (-)NCBI
mRatBN7.21826,872,427 - 27,047,835 (-)NCBI
RefSeq Acc Id: XM_039096722   ⟹   XP_038952650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81827,146,526 - 27,186,204 (-)NCBI
mRatBN7.21826,872,427 - 26,909,522 (-)NCBI
RefSeq Acc Id: NP_955408   ⟸   NM_199376
- Peptide Label: precursor
- UniProtKB: Q6P6S4 (UniProtKB/Swiss-Prot),   A6J2X3 (UniProtKB/TrEMBL),   A0A8I6ANJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770247   ⟸   XM_008772025
- Peptide Label: isoform X1
- UniProtKB: Q6P6S4 (UniProtKB/Swiss-Prot),   A6J2X3 (UniProtKB/TrEMBL),   A0A8I6ANJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456394   ⟸   XM_017600905
- Peptide Label: isoform X1
- UniProtKB: Q6P6S4 (UniProtKB/Swiss-Prot),   A6J2X3 (UniProtKB/TrEMBL),   A0A8I6ANJ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000026895   ⟸   ENSRNOT00000026895
RefSeq Acc Id: XP_038952646   ⟸   XM_039096718
- Peptide Label: isoform X1
- UniProtKB: Q6P6S4 (UniProtKB/Swiss-Prot),   A6J2X3 (UniProtKB/TrEMBL),   A0A8I6ANJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952648   ⟸   XM_039096720
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZSQ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952650   ⟸   XM_039096722
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000081504   ⟸   ENSRNOT00000105808
RefSeq Acc Id: ENSRNOP00000097662   ⟸   ENSRNOT00000102716
RefSeq Acc Id: ENSRNOP00000076899   ⟸   ENSRNOT00000113606
RefSeq Acc Id: ENSRNOP00000078831   ⟸   ENSRNOT00000104681
RefSeq Acc Id: ENSRNOP00000097578   ⟸   ENSRNOT00000107530
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P6S4-F1-model_v2 AlphaFold Q6P6S4 1-465 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700707
Promoter ID:EPDNEW_R11230
Type:initiation region
Name:Sil1_1
Description:SIL1 nucleotide exchange factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01828,301,878 - 28,301,938EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735103 AgrOrtholog
BioCyc Gene G2FUF-7915 BioCyc
Ensembl Genes ENSRNOG00000019826 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026895 ENTREZGENE
  ENSRNOT00000026895.6 UniProtKB/Swiss-Prot
  ENSRNOT00000102716.1 UniProtKB/TrEMBL
  ENSRNOT00000104681.1 UniProtKB/TrEMBL
  ENSRNOT00000105808.1 UniProtKB/TrEMBL
  ENSRNOT00000107530.1 UniProtKB/TrEMBL
  ENSRNOT00000113606.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5598825 IMAGE-MGC_LOAD
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide_exch_fac_Fes1 UniProtKB/TrEMBL
KEGG Report rno:291673 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72590 IMAGE-MGC_LOAD
NCBI Gene 291673 ENTREZGENE
PANTHER NUCLEOTIDE EXCHANGE FACTOR SIL1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN FOLDING REGULATOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Fes1 UniProtKB/TrEMBL
PhenoGen Sil1 PhenoGen
RatGTEx ENSRNOG00000019826 RatGTEx
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y965_RAT UniProtKB/TrEMBL
  A0A8I5ZLN1_RAT UniProtKB/TrEMBL
  A0A8I5ZSQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ANJ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AT30_RAT UniProtKB/TrEMBL
  A6J2X3 ENTREZGENE, UniProtKB/TrEMBL
  A6J2X4_RAT UniProtKB/TrEMBL
  Q6P6S4 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-09-18 Sil1  SIL1 nucleotide exchange factor  Sil1  SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-04 Sil1  SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)  Sil1  endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Sil1  endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)  MGC72590  similar to endoplasmic reticulum chaperone SIL1 homolog  Symbol and Name updated 1299863 APPROVED