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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Hp1bp3 | Rat | (S)-nicotine | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Nicotine results in increased expression of HP1BP3 mRNA | CTD | PMID:16949557 | Hp1bp3 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of HP1BP3 mRNA | CTD | PMID:22206623 | Hp1bp3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of HP1BP3 mRNA | CTD | PMID:34747641 | Hp1bp3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of HP1BP3 mRNA | CTD | PMID:33387578 | Hp1bp3 | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | HP1BP3 (Homo sapiens) | 6480464 | [Furaldehyde co-treated with pyrogallol 1,3-dimethyl ether] results in decreased expression of HP1BP3 protein | CTD | PMID:38598786 | Hp1bp3 | Rat | 2-methylcholine | affects expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of HP1BP3 mRNA | CTD | PMID:21179406 | Hp1bp3 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of HP1BP3 mRNA | CTD | PMID:20188158 | Hp1bp3 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of HP1BP3 mRNA | CTD | PMID:18648102 | Hp1bp3 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... | CTD | PMID:36041667 | Hp1bp3 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of HP1BP3 protein | CTD | PMID:34186270 | Hp1bp3 | Rat | all-trans-retinoic acid | decreases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of HP1BP3 mRNA | CTD | PMID:33167477 | Hp1bp3 | Rat | allethrin | multiple interactions | EXP | | 6480464 | [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in more ... | CTD | PMID:33051911|PMID:33396045|PMID:34896426 | Hp1bp3 | Rat | antirheumatic drug | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of HP1BP3 mRNA | CTD | PMID:24449571 | Hp1bp3 | Rat | aristolochic acid A | decreases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of HP1BP3 mRNA | CTD | PMID:33212167 | Hp1bp3 | Rat | arsane | affects methylation | ISO | HP1BP3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of HP1BP3 gene | CTD | PMID:25304211 | Hp1bp3 | Rat | arsenic atom | affects methylation | ISO | HP1BP3 (Homo sapiens) | 6480464 | Arsenic affects the methylation of HP1BP3 gene | CTD | PMID:25304211 | Hp1bp3 | Rat | avobenzone | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | avobenzone results in increased expression of HP1BP3 mRNA | CTD | PMID:31016361 | Hp1bp3 | Rat | benzo[a]pyrene | multiple interactions | ISO | Hp1bp3 (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to HP1BP3 promoter] | CTD | PMID:19654925 | Hp1bp3 | Rat | benzo[a]pyrene | increases methylation | ISO | HP1BP3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of HP1BP3 promoter | CTD | PMID:27901495 | Hp1bp3 | Rat | beta-lapachone | decreases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of HP1BP3 mRNA | CTD | PMID:38218311 | Hp1bp3 | Rat | beta-naphthoflavone | decreases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | beta-Naphthoflavone results in decreased expression of HP1BP3 protein | CTD | PMID:39638853 | Hp1bp3 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of HP1BP3 mRNA | CTD | PMID:33754040 | Hp1bp3 | Rat | bisphenol A | increases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of HP1BP3 mRNA | CTD | PMID:26063408 | Hp1bp3 | Rat | bisphenol A | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of HP1BP3 protein | CTD | PMID:37567409 | Hp1bp3 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... | CTD | PMID:36041667 | Hp1bp3 | Rat | bisphenol A | decreases methylation | ISO | Hp1bp3 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of HP1BP3 promoter | CTD | PMID:27312807 | Hp1bp3 | Rat | bisphenol A | increases methylation | ISO | Hp1bp3 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of HP1BP3 promoter | CTD | PMID:27312807 | Hp1bp3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of HP1BP3 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016 | Hp1bp3 | Rat | bisphenol AF | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of HP1BP3 protein | CTD | PMID:34186270 | Hp1bp3 | Rat | Bisphenol B | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of HP1BP3 protein | CTD | PMID:34186270 | Hp1bp3 | Rat | bisphenol F | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of HP1BP3 protein | CTD | PMID:34186270 | Hp1bp3 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of more ... | CTD | PMID:36041667 | Hp1bp3 | Rat | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of HP1BP3 protein | CTD | PMID:28903499 | Hp1bp3 | Rat | butanal | decreases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of HP1BP3 mRNA | CTD | PMID:26079696 | Hp1bp3 | Rat | cadmium dichloride | decreases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of HP1BP3 mRNA | CTD | PMID:38568856 | Hp1bp3 | Rat | caffeine | affects phosphorylation | ISO | HP1BP3 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of HP1BP3 protein | CTD | PMID:35688186 | Hp1bp3 | Rat | carbon nanotube | decreases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of HP1BP3 mRNA; Nanotubes, Carbon results in decreased more ... | CTD | PMID:25554681 | Hp1bp3 | Rat | cisplatin | increases phosphorylation | ISO | Hp1bp3 (Mus musculus) | 6480464 | Cisplatin results in increased phosphorylation of HP1BP3 protein | CTD | PMID:22006019 | Hp1bp3 | Rat | cyhalothrin | multiple interactions | EXP | | 6480464 | [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in more ... | CTD | PMID:33051911|PMID:33396045|PMID:34896426 | Hp1bp3 | Rat | cypermethrin | multiple interactions | EXP | | 6480464 | [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in more ... | CTD | PMID:33051911|PMID:33396045|PMID:34896426 | Hp1bp3 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of HP1BP3 mRNA | CTD | PMID:21266533 | Hp1bp3 | Rat | dihydroartemisinin | affects binding | ISO | HP1BP3 (Homo sapiens) | 6480464 | artenimol analog binds to HP1BP3 protein | CTD | PMID:26340163 | Hp1bp3 | Rat | doxorubicin | multiple interactions | ISO | HP1BP3 (Homo sapiens) | 6480464 | [VRK1 protein affects the susceptibility to Doxorubicin] which affects the phosphorylation of HP1BP3 protein | CTD | PMID:38367682 | Hp1bp3 | Rat | ethanol | affects splicing | ISO | Hp1bp3 (Mus musculus) | 6480464 | Ethanol affects the splicing of HP1BP3 mRNA | CTD | PMID:30319688 | Hp1bp3 | Rat | fenthion | decreases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | Fenthion results in decreased expression of HP1BP3 mRNA | CTD | PMID:34813904 | Hp1bp3 | Rat | fenvalerate | multiple interactions | EXP | | 6480464 | [Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in more ... | CTD | PMID:33051911|PMID:33396045|PMID:34896426 | Hp1bp3 | Rat | FR900359 | affects phosphorylation | ISO | HP1BP3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of HP1BP3 protein | CTD | PMID:37730182 | Hp1bp3 | Rat | furfural | multiple interactions | ISO | HP1BP3 (Homo sapiens) | 6480464 | [Furaldehyde co-treated with pyrogallol 1,3-dimethyl ether] results in decreased expression of HP1BP3 protein; [Sodium Chloride more ... | CTD | PMID:38598786 | Hp1bp3 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of HP1BP3 mRNA | CTD | PMID:33387578 | Hp1bp3 | Rat | hexane | decreases methylation | EXP | | 6480464 | n-hexane results in decreased methylation of HP1BP3 promoter | CTD | PMID:23740543 | Hp1bp3 | Rat | ivermectin | decreases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of HP1BP3 protein | CTD | PMID:32959892 | Hp1bp3 | Rat | lead diacetate | multiple interactions | ISO | HP1BP3 (Homo sapiens) | 6480464 | [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of HP1BP3 mRNA | CTD | PMID:22839698 | Hp1bp3 | Rat | lead(0) | affects expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Lead affects the expression of HP1BP3 mRNA | CTD | PMID:28903495 | Hp1bp3 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of HP1BP3 mRNA | CTD | PMID:30467583 | Hp1bp3 | Rat | methylparaben | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | methylparaben results in increased expression of HP1BP3 mRNA | CTD | PMID:31745603 | Hp1bp3 | Rat | nicotine | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Nicotine results in increased expression of HP1BP3 mRNA | CTD | PMID:16949557 | Hp1bp3 | Rat | paracetamol | affects expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of HP1BP3 mRNA | CTD | PMID:17562736 | Hp1bp3 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of HP1BP3 mRNA | CTD | PMID:33387578 | Hp1bp3 | Rat | paracetamol | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of HP1BP3 mRNA | CTD | PMID:22230336 | Hp1bp3 | Rat | pentachlorophenol | increases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of HP1BP3 mRNA | CTD | PMID:23892564 | Hp1bp3 | Rat | perfluorooctanoic acid | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of HP1BP3 protein | CTD | PMID:26879310 | Hp1bp3 | Rat | pirinixic acid | increases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of HP1BP3 mRNA | CTD | PMID:23811191 | Hp1bp3 | Rat | potassium dichromate | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Potassium Dichromate results in increased expression of HP1BP3 protein | CTD | PMID:23718831 | Hp1bp3 | Rat | pyrethrins | affects expression | EXP | | 6480464 | Pyrethrins affects the expression of HP1BP3 mRNA | CTD | PMID:34896426 | Hp1bp3 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of HP1BP3 protein | CTD | PMID:35544339 | Hp1bp3 | Rat | sodium chloride | multiple interactions | ISO | HP1BP3 (Homo sapiens) | 6480464 | [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of HP1BP3 protein; [Sodium Chloride co-treated more ... | CTD | PMID:38598786 | Hp1bp3 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of HP1BP3 mRNA | CTD | PMID:15336504 | Hp1bp3 | Rat | titanium dioxide | increases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of HP1BP3 mRNA | CTD | PMID:29264374 | Hp1bp3 | Rat | titanium dioxide | increases methylation | ISO | HP1BP3 (Homo sapiens) | 6480464 | titanium dioxide results in increased methylation of HP1BP3 promoter | CTD | PMID:34973136 | Hp1bp3 | Rat | titanium dioxide | increases methylation | ISO | Hp1bp3 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of HP1BP3 promoter | CTD | PMID:35295148 | Hp1bp3 | Rat | triptonide | decreases expression | ISO | Hp1bp3 (Mus musculus) | 6480464 | triptonide results in decreased expression of HP1BP3 mRNA | CTD | PMID:33045310 | Hp1bp3 | Rat | valproic acid | decreases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of HP1BP3 mRNA | CTD | PMID:28001369|PMID:29154799 | Hp1bp3 | Rat | zinc protoporphyrin | multiple interactions | ISO | HP1BP3 (Homo sapiens) | 6480464 | [lead acetate co-treated with zinc protoporphyrin] results in decreased expression of HP1BP3 mRNA | CTD | PMID:22839698 | Hp1bp3 | Rat | zoledronic acid | increases expression | ISO | HP1BP3 (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of HP1BP3 mRNA | CTD | PMID:20977926 | |