Cry1 (cryptochrome circadian regulator 1) - Rat Genome Database

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Gene: Cry1 (cryptochrome circadian regulator 1) Rattus norvegicus
Analyze
Symbol: Cry1
Name: cryptochrome circadian regulator 1
RGD ID: 735083
Description: Predicted to enable several functions, including E-box binding activity; FAD binding activity; and enzyme binding activity. Predicted to be involved in several processes, including negative regulation of cell communication; regulation of gluconeogenesis; and regulation of protein ubiquitination. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in delayed sleep phase syndrome. Orthologous to human CRY1 (cryptochrome circadian regulator 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cryptochrome 1 (photolyase-like); cryptochrome circadian clock 1; cryptochrome-1; MGC124541
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8720,417,526 - 20,481,791 (+)NCBIGRCr8
mRatBN7.2718,529,823 - 18,594,092 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl718,529,823 - 18,594,091 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx720,497,139 - 20,554,961 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0722,659,833 - 22,717,659 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0722,436,800 - 22,494,621 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0724,534,593 - 24,634,098 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl724,534,615 - 24,634,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0726,277,264 - 26,278,124 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0724,684,038 - 24,784,329 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4720,643,879 - 20,709,216 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1720,664,607 - 20,729,486 (+)NCBI
Celera715,758,113 - 15,822,171 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-epicatechin-3-O-gallate  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxynon-2-enal  (ISO)
4-nitro-m-cresol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
aristolochic acid A  (EXP)
azoxystrobin  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bromobenzene  (EXP)
buspirone  (EXP)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP,ISO)
cefaloridine  (EXP)
chloroprene  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
cocaine hydrochloride  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
deoxynivalenol  (ISO)
Dibutyl phosphate  (ISO)
dichloromethane  (ISO)
diclofenac  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
fluoxetine  (ISO)
folic acid  (ISO)
folpet  (ISO)
furan  (EXP)
gallic acid  (ISO)
gallocatechin  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
imidacloprid  (EXP)
inulin  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
melatonin  (EXP)
methamphetamine  (EXP)
methimazole  (EXP)
methylarsonic acid  (ISO)
mitomycin C  (ISO)
Monobutylphthalate  (EXP)
monosodium L-glutamate  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodimethylamine  (EXP,ISO)
nefazodone  (EXP)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenformin  (EXP)
phenobarbital  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
prednisolone  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
silicon dioxide  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
streptozocin  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (EXP)
triadimefon  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
mitochondrion  (ISO)
nucleus  (IBA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Reduced expression of circadian clock genes in male alcoholic patients. Huang MC, etal., Alcohol Clin Exp Res. 2010 Nov;34(11):1899-904. doi: 10.1111/j.1530-0277.2010.01278.x. Epub 2010 Aug 24.
4. mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop. Kume K, etal., Cell 1999 Jul 23;98(2):193-205.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum. Uz T, etal., Neuroscience. 2005;134(4):1309-16. doi: 10.1016/j.neuroscience.2005.05.003.
Additional References at PubMed
PMID:8909283   PMID:9383998   PMID:9801304   PMID:10217146   PMID:11555636   PMID:11889036   PMID:12024206   PMID:12150932   PMID:12397359   PMID:12477932   PMID:12738229   PMID:12832412  
PMID:12843397   PMID:14672706   PMID:15147242   PMID:15226430   PMID:15529004   PMID:17264215   PMID:17310242   PMID:18316400   PMID:18614015   PMID:19129230   PMID:19299583   PMID:19387896  
PMID:19605937   PMID:19833968   PMID:20424134   PMID:20852621   PMID:21236481   PMID:21613214   PMID:21768648   PMID:22170608   PMID:22208286   PMID:22894897   PMID:23056261   PMID:23133559  
PMID:23418588   PMID:23531614   PMID:23575670   PMID:23616524   PMID:24089055   PMID:24158435   PMID:24378737   PMID:24385426   PMID:24489120   PMID:24619734   PMID:26431207   PMID:28683290  
PMID:28751364   PMID:28790135   PMID:29561690   PMID:29894471   PMID:29937374   PMID:36376275  


Genomics

Comparative Map Data
Cry1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8720,417,526 - 20,481,791 (+)NCBIGRCr8
mRatBN7.2718,529,823 - 18,594,092 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl718,529,823 - 18,594,091 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx720,497,139 - 20,554,961 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0722,659,833 - 22,717,659 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0722,436,800 - 22,494,621 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0724,534,593 - 24,634,098 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl724,534,615 - 24,634,097 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0726,277,264 - 26,278,124 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0724,684,038 - 24,784,329 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4720,643,879 - 20,709,216 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1720,664,607 - 20,729,486 (+)NCBI
Celera715,758,113 - 15,822,171 (+)NCBICelera
Cytogenetic Map7q13NCBI
CRY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812106,991,364 - 107,093,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12106,991,364 - 107,093,549 (-)EnsemblGRCh38hg38GRCh38
GRCh3712107,385,142 - 107,487,327 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612105,909,272 - 106,011,455 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412105,887,608 - 105,989,792NCBI
Celera12107,050,701 - 107,153,165 (-)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12104,445,641 - 104,548,152 (-)NCBIHuRef
CHM1_112107,350,774 - 107,453,198 (-)NCBICHM1_1
T2T-CHM13v2.012106,954,997 - 107,057,182 (-)NCBIT2T-CHM13v2.0
Cry1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391084,967,564 - 85,020,918 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1084,967,564 - 85,020,928 (-)EnsemblGRCm39 Ensembl
GRCm381085,131,700 - 85,185,054 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1085,131,700 - 85,185,064 (-)EnsemblGRCm38mm10GRCm38
MGSCv371084,594,445 - 84,647,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361084,561,499 - 84,614,853 (-)NCBIMGSCv36mm8
Celera1087,108,048 - 87,162,027 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.63NCBI
Cry1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540540,874,322 - 40,941,664 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540540,878,227 - 40,941,664 (-)NCBIChiLan1.0ChiLan1.0
CRY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210115,047,336 - 115,151,695 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112115,043,733 - 115,148,095 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012104,558,874 - 104,658,833 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112107,952,836 - 108,052,484 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12107,954,262 - 108,052,484 (-)Ensemblpanpan1.1panPan2
CRY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11031,681,098 - 31,792,995 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1031,681,288 - 31,780,306 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1031,665,919 - 31,778,539 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01032,522,572 - 32,634,406 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1032,522,596 - 32,623,626 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11032,259,347 - 32,370,641 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01032,549,505 - 32,661,061 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01032,735,159 - 32,847,092 (+)NCBIUU_Cfam_GSD_1.0
Cry1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494514,918,737 - 14,984,383 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364927,929,138 - 7,995,579 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364927,929,138 - 7,994,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRY1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl513,275,545 - 13,364,593 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1513,275,265 - 13,429,566 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2513,128,680 - 13,217,202 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CRY1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111102,200,822 - 102,306,165 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11102,204,224 - 102,306,182 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037142,748,733 - 142,851,088 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cry1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247502,465,999 - 2,529,251 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cry1
325 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:63
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000009124
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)71816950526029351Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat

Markers in Region
AI412155  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2718,593,956 - 18,594,053 (+)MAPPERmRatBN7.2
Rnor_6.0724,633,963 - 24,634,059NCBIRnor6.0
Rnor_5.0724,784,194 - 24,784,290UniSTSRnor5.0
RGSC_v3.4720,709,081 - 20,709,177UniSTSRGSC3.4
Celera715,822,036 - 15,822,132UniSTS
Cytogenetic Map7q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000009124   ⟹   ENSRNOP00000009124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl718,529,823 - 18,594,091 (+)Ensembl
Rnor_6.0 Ensembl724,534,615 - 24,634,097 (+)Ensembl
RefSeq Acc Id: NM_198750   ⟹   NP_942045
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,417,526 - 20,481,791 (+)NCBI
mRatBN7.2718,529,823 - 18,594,092 (+)NCBI
Rnor_6.0724,534,615 - 24,634,098 (+)NCBI
Rnor_5.0726,277,264 - 26,278,124 (-)NCBI
RGSC_v3.4720,643,879 - 20,709,216 (+)RGD
Celera715,758,113 - 15,822,171 (+)RGD
Sequence:
RefSeq Acc Id: XM_008765225   ⟹   XP_008763447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,418,057 - 20,481,791 (+)NCBI
mRatBN7.2718,530,328 - 18,594,092 (+)NCBI
Rnor_6.0724,534,593 - 24,634,098 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063263193   ⟹   XP_063119263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8720,418,057 - 20,481,791 (+)NCBI
RefSeq Acc Id: NP_942045   ⟸   NM_198750
- UniProtKB: Q717B5 (UniProtKB/Swiss-Prot),   Q32Q86 (UniProtKB/Swiss-Prot),   A6IFE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763447   ⟸   XM_008765225
- Peptide Label: isoform X1
- UniProtKB: Q717B5 (UniProtKB/Swiss-Prot),   Q32Q86 (UniProtKB/Swiss-Prot),   A6IFE1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009124   ⟸   ENSRNOT00000009124
RefSeq Acc Id: XP_063119263   ⟸   XM_063263193
- Peptide Label: isoform X1
- UniProtKB: Q717B5 (UniProtKB/Swiss-Prot),   Q32Q86 (UniProtKB/Swiss-Prot)
Protein Domains
Photolyase/cryptochrome alpha/beta

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q32Q86-F1-model_v2 AlphaFold Q32Q86 1-588 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695096
Promoter ID:EPDNEW_R5621
Type:initiation region
Name:Cry1_1
Description:cryptochrome circadian regulator 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0724,534,569 - 24,534,629EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735083 AgrOrtholog
BioCyc Gene G2FUF-34631 BioCyc
Ensembl Genes ENSRNOG00000006622 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055020181 UniProtKB/Swiss-Prot
  ENSRNOG00060028555 UniProtKB/Swiss-Prot
  ENSRNOG00065025283 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009124.6 UniProtKB/Swiss-Prot
  ENSRNOT00055034462 UniProtKB/Swiss-Prot
  ENSRNOT00060049632 UniProtKB/Swiss-Prot
  ENSRNOT00065043566 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.620 UniProtKB/Swiss-Prot
  DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HUPs UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7939194 IMAGE-MGC_LOAD
InterPro Crypto/Photolyase_FAD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Crypto/Photolyase_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cryptochr/Photolyase_FAD-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cryptochrome/DNA_photolyase_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA_photolyase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:299691 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124541 IMAGE-MGC_LOAD
NCBI Gene 299691 ENTREZGENE
PANTHER CRYPTOCHROME UniProtKB/TrEMBL
  CRYPTOCHROME-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11455 UniProtKB/Swiss-Prot
Pfam DNA_photolyase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD_binding_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cry1 PhenoGen
PROSITE PHR_CRY_ALPHA_BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006622 RatGTEx
  ENSRNOG00055020181 RatGTEx
  ENSRNOG00060028555 RatGTEx
  ENSRNOG00065025283 RatGTEx
Superfamily-SCOP Cryptochrome/photolyase FAD-binding domain UniProtKB/TrEMBL
  Cryptochrome/photolyase, N-terminal domain UniProtKB/TrEMBL
  SSF48173 UniProtKB/Swiss-Prot
  SSF52425 UniProtKB/Swiss-Prot
UniProt A6IFE1 ENTREZGENE, UniProtKB/TrEMBL
  CRY1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q717B5 ENTREZGENE
UniProt Secondary Q717B5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-10-09 Cry1  cryptochrome circadian regulator 1  Cry1  cryptochrome circadian clock 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-01-23 Cry1  cryptochrome circadian clock 1  Cry1  cryptochrome 1 (photolyase-like)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Cry1  cryptochrome 1 (photolyase-like)      Symbol and Name status set to approved 1299863 APPROVED