Gask1b (golgi associated kinase 1B) - Rat Genome Database

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Gene: Gask1b (golgi associated kinase 1B) Rattus norvegicus
Analyze
Symbol: Gask1b
Name: golgi associated kinase 1B
RGD ID: 735075
Description: Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human GASK1B (golgi associated kinase 1B); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ened; expressed in nerve and epithelium during development; Fam198b; family with sequence similarity 198, member B; Golgi-associated kinase 1B; MGC72614; Unknown (protein for MGC:72614)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82167,345,738 - 167,410,606 (+)NCBIGRCr8
mRatBN7.22165,047,689 - 165,112,479 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2165,047,684 - 165,112,477 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2172,264,116 - 172,321,131 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02170,280,250 - 170,336,795 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02164,889,147 - 164,945,695 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02178,678,946 - 178,751,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2178,679,041 - 178,750,668 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02198,087,533 - 198,160,178 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42171,368,285 - 171,432,819 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12171,318,390 - 171,382,924 (+)NCBI
Celera2159,137,934 - 159,195,169 (+)NCBICelera
Cytogenetic Map2q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-dichloroaniline  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (EXP)
atrazine  (EXP)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dibenz[a,h]anthracene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dimethylarsinic acid  (EXP)
diquat  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
fucoxanthin  (ISO)
fulvestrant  (ISO)
furan  (EXP)
gemcitabine  (ISO)
glucose  (ISO)
glycidol  (EXP)
hydroquinone  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lidocaine  (EXP)
mercury dibromide  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
oxaliplatin  (EXP,ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
succimer  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trametinib  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data
Gask1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82167,345,738 - 167,410,606 (+)NCBIGRCr8
mRatBN7.22165,047,689 - 165,112,479 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2165,047,684 - 165,112,477 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2172,264,116 - 172,321,131 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02170,280,250 - 170,336,795 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02164,889,147 - 164,945,695 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02178,678,946 - 178,751,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2178,679,041 - 178,750,668 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02198,087,533 - 198,160,178 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42171,368,285 - 171,432,819 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12171,318,390 - 171,382,924 (+)NCBI
Celera2159,137,934 - 159,195,169 (+)NCBICelera
Cytogenetic Map2q33NCBI
GASK1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384158,124,474 - 158,173,025 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4158,124,474 - 158,173,318 (-)EnsemblGRCh38hg38GRCh38
GRCh374159,045,626 - 159,094,177 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364159,265,211 - 159,313,652 (-)NCBINCBI36Build 36hg18NCBI36
Celera4156,388,183 - 156,436,659 (-)NCBICelera
Cytogenetic Map4q32.1NCBI
HuRef4154,797,096 - 154,845,572 (-)NCBIHuRef
CHM1_14159,022,919 - 159,071,420 (-)NCBICHM1_1
T2T-CHM13v2.04161,476,702 - 161,525,241 (-)NCBIT2T-CHM13v2.0
Gask1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39379,791,795 - 79,853,585 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl379,791,840 - 79,853,587 (+)EnsemblGRCm39 Ensembl
GRCm38379,884,484 - 79,946,278 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl379,884,533 - 79,946,280 (+)EnsemblGRCm38mm10GRCm38
MGSCv37379,689,852 - 79,750,200 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36379,971,915 - 80,029,312 (+)NCBIMGSCv36mm8
Celera379,913,831 - 79,976,828 (+)NCBICelera
Cytogenetic Map3E3NCBI
cM Map335.13NCBI
Gask1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554719,284,986 - 9,327,337 (+)NCBIChiLan1.0ChiLan1.0
GASK1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23155,990,288 - 156,048,438 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14156,345,551 - 156,403,695 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04150,443,110 - 150,492,282 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14162,256,117 - 162,304,198 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4162,246,728 - 162,304,069 (-)Ensemblpanpan1.1panPan2
GASK1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11555,338,536 - 55,384,521 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1555,340,058 - 55,385,857 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1555,700,454 - 55,746,527 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01556,081,806 - 56,127,861 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1556,083,333 - 56,129,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11555,321,092 - 55,367,138 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01555,420,300 - 55,466,545 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01555,732,909 - 55,778,982 (-)NCBIUU_Cfam_GSD_1.0
Gask1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530134,852,768 - 34,909,815 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365764,635,719 - 4,694,200 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365764,635,762 - 4,694,152 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GASK1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl847,036,899 - 47,098,718 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1847,036,905 - 47,133,914 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2849,264,506 - 49,361,184 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GASK1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17104,700,841 - 104,749,213 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7104,699,986 - 104,747,769 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603784,402,934 - 84,457,019 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gask1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624848420,751 - 463,903 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gask1b
668 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:701
Count of miRNA genes:287
Interacting mature miRNAs:362
Transcripts:ENSRNOT00000013524
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072175950118Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2152413072175950118Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072175950118Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072175950118Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072175950118Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2152413072175950118Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
631520Bp73Blood pressure QTL 730.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147686913168355276Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat

Markers in Region
RH127673  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22165,112,184 - 165,112,386 (+)MAPPERmRatBN7.2
Rnor_6.02178,749,760 - 178,749,961NCBIRnor6.0
Rnor_5.02198,158,479 - 198,158,680UniSTSRnor5.0
RGSC_v3.42171,432,525 - 171,432,726UniSTSRGSC3.4
Celera2159,194,875 - 159,195,076UniSTS
Cytogenetic Map2q33UniSTS
RH131521  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22165,110,846 - 165,111,048 (+)MAPPERmRatBN7.2
Rnor_6.02178,748,422 - 178,748,623NCBIRnor6.0
Rnor_5.02198,157,141 - 198,157,342UniSTSRnor5.0
RGSC_v3.42171,431,187 - 171,431,388UniSTSRGSC3.4
Celera2159,193,537 - 159,193,738UniSTS
RH 3.4 Map21060.2UniSTS
Cytogenetic Map2q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 42 8 11 2 2 7 28 33 11 2
Low 3 1 49 41 8 41 6 9 67 7 7 6
Below cutoff 1

Sequence


RefSeq Acc Id: ENSRNOT00000013524   ⟹   ENSRNOP00000013525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2165,047,684 - 165,112,477 (+)Ensembl
Rnor_6.0 Ensembl2178,679,041 - 178,750,051 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088686   ⟹   ENSRNOP00000073355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2178,679,395 - 178,750,668 (+)Ensembl
RefSeq Acc Id: NM_199105   ⟹   NP_954536
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82167,345,842 - 167,410,606 (+)NCBI
mRatBN7.22165,047,717 - 165,112,479 (+)NCBI
Rnor_6.02178,679,041 - 178,750,054 (+)NCBI
Rnor_5.02198,087,533 - 198,160,178 (+)NCBI
RGSC_v3.42171,368,285 - 171,432,819 (+)RGD
Celera2159,137,934 - 159,195,169 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232514   ⟹   XP_006232576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82167,345,738 - 167,410,606 (+)NCBI
mRatBN7.22165,047,689 - 165,112,031 (+)NCBI
Rnor_6.02178,678,946 - 178,751,459 (+)NCBI
Rnor_5.02198,087,533 - 198,160,178 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_954536 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232576 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH61747 (Get FASTA)   NCBI Sequence Viewer  
  EDM00862 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013525.3
  ENSRNOP00055001805
  ENSRNOP00060008537
  ENSRNOP00065042868
GenBank Protein Q6P7B4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_954536   ⟸   NM_199105
- UniProtKB: Q6P7B4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006232576   ⟸   XM_006232514
- Peptide Label: isoform X1
- UniProtKB: Q6P7B4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013525   ⟸   ENSRNOT00000013524
RefSeq Acc Id: ENSRNOP00000073355   ⟸   ENSRNOT00000088686

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P7B4-F1-model_v2 AlphaFold Q6P7B4 1-516 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691387
Promoter ID:EPDNEW_R1911
Type:initiation region
Name:Fam198b_2
Description:family with sequence similarity 198, member B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1913  EPDNEW_R1912  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02178,679,008 - 178,679,068EPDNEW
RGD ID:13691403
Promoter ID:EPDNEW_R1912
Type:initiation region
Name:Fam198b_3
Description:family with sequence similarity 198, member B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1911  EPDNEW_R1913  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02178,679,461 - 178,679,521EPDNEW
RGD ID:13691388
Promoter ID:EPDNEW_R1913
Type:multiple initiation site
Name:Fam198b_1
Description:family with sequence similarity 198, member B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R1911  EPDNEW_R1912  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02178,680,520 - 178,680,580EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735075 AgrOrtholog
BioCyc Gene G2FUF-52712 BioCyc
Ensembl Genes ENSRNOG00000010183 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055001437 UniProtKB/Swiss-Prot
  ENSRNOG00060006965 UniProtKB/Swiss-Prot
  ENSRNOG00065030188 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000013524.6 UniProtKB/Swiss-Prot
  ENSRNOT00055002339 UniProtKB/Swiss-Prot
  ENSRNOT00060011414 UniProtKB/Swiss-Prot
  ENSRNOT00065052089 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5599685 IMAGE-MGC_LOAD
InterPro FAM198 UniProtKB/Swiss-Prot
KEGG Report rno:310540 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72614 IMAGE-MGC_LOAD
NCBI Gene 310540 ENTREZGENE
PANTHER GOLGI-ASSOCIATED KINASE 1B UniProtKB/Swiss-Prot
  PTHR15905 UniProtKB/Swiss-Prot
Pfam FAM198 UniProtKB/Swiss-Prot
PhenoGen Gask1b PhenoGen
RatGTEx ENSRNOG00000010183 RatGTEx
  ENSRNOG00055001437 RatGTEx
  ENSRNOG00060006965 RatGTEx
  ENSRNOG00065030188 RatGTEx
UniProt GAK1B_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-10-30 Gask1b  golgi associated kinase 1B  Fam198b  family with sequence similarity 198, member B  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-04-23 Fam198b  family with sequence similarity 198, member B  MGC72614  Unknown (protein for MGC:72614)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 MGC72614        Symbol and Name status set to provisional 70820 PROVISIONAL