Lat (linker for activation of T cells)

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Gene: Lat (linker for activation of T cells) Mus musculus

Analyze

Symbol:

Lat

Name:

linker for activation of T cells

RGD ID:

734455

MGI Page

MGI

Description:

Predicted to enable protein kinase binding activity and signaling receptor complex adaptor activity. Acts upstream of or within gene expression; inflammatory response; and lymphocyte homeostasis. Located in cell-cell junction and immunological synapse. Part of COP9 signalosome. Is expressed in liver and thymus primordium. Used to study IgG4-related disease. Human ortholog(s) of this gene implicated in immunodeficiency 52. Orthologous to human LAT (linker for activation of T cells).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

36 kDa phospho-tyrosine adapter protein; linker for activation of T-cells family member 1; linker protein; p36-38; pp36

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	125,962,999 - 125,968,877 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	125,962,996 - 125,968,742 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	126,363,827 - 126,369,705 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	126,363,824 - 126,369,570 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	133,507,341 - 133,513,048 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	126,154,975 - 126,160,682 (-)	NCBI		MGSCv36	mm8
Celera	7	126,216,064 - 126,221,729 (-)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

16p11.2 Deletion Syndrome (ISO)

amyotrophic lateral sclerosis type 1 (ISO)

Brody myopathy (ISO)

chromosome 16p11.2 deletion syndrome (ISO)

genetic disease (ISO)

IgG4-related disease (IAGP)

immunodeficiency 52 (ISO)

liver disease (ISO)

neuronal ceroid lipofuscinosis (ISO)

schizophrenia (ISO)

toxic encephalopathy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxynon-2-enal (ISO)

ammonium chloride (ISO)

amphetamine (ISO)

antigen (EXP)

antirheumatic drug (ISO)

arsenous acid (ISO)

beauvericin (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

buta-1,3-diene (EXP)

carbon nanotube (EXP)

chromium(6+) (EXP)

cisplatin (ISO)

citalopram (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (EXP,ISO)

CU-O LINKAGE (ISO)

cyclophosphamide (EXP)

dexamethasone (EXP,ISO)

diarsenic trioxide (ISO)

diethylstilbestrol (EXP)

endosulfan (ISO)

fenvalerate (ISO)

flavonoids (ISO)

gentamycin (ISO)

indometacin (ISO)

lead diacetate (EXP)

leflunomide (ISO)

malathion (ISO)

methotrexate (EXP)

methyl beta-cyclodextrin (ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

nitrobenzenes (ISO)

oxaliplatin (ISO)

ozone (EXP)

paracetamol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (EXP)

resveratrol (ISO)

silicon dioxide (EXP,ISO)

silver atom (EXP)

silver(0) (EXP)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

topotecan (ISO)

Tributyltin oxide (EXP)

trichloroethene (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adaptive immune response (IEA)

calcium-mediated signaling (ISO)

cellular defense response (TAS)

gene expression (IMP)

homeostasis of number of cells (IMP)

immune response (IBA,ISO)

immune system process (IEA)

inflammatory response (IBA,IMP)

integrin-mediated signaling pathway (ISO)

intracellular signal transduction (IBA,ISO)

lymphocyte homeostasis (IMP)

mast cell degranulation (IEA)

positive regulation of protein kinase activity (IBA)

Ras protein signal transduction (ISO)

regulation of T cell activation (IBA,ISO)

signal transduction (IEA)

T cell receptor signaling pathway (ISO)

transmembrane receptor protein tyrosine kinase signaling pathway (TAS)

Cellular Component

cell-cell junction (IDA)

COP9 signalosome (IDA)

Golgi apparatus (ISO)

immunological synapse (IDA,ISO)

membrane (ISO)

plasma membrane (ISO)

plasma membrane (TAS)

Molecular Function

protein binding (IPI)

protein kinase binding (IBA,ISO)

signaling receptor complex adaptor activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Fc epsilon receptor mediated signaling pathway (ISO)

T cell receptor signaling pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal B cell activation (IAGP)

abnormal B cell differentiation (IAGP)

abnormal B cell number (IAGP)

abnormal B cell physiology (IAGP)

abnormal CD4-positive, alpha beta T cell morphology (IAGP)

abnormal CD8-positive, alpha beta T cell morphology (IAGP)

abnormal cytokine secretion (IAGP)

abnormal double-negative T cell morphology (IAGP)

abnormal effector T cell morphology (IAGP)

abnormal gamma-delta T cell differentiation (IAGP)

abnormal immune serum protein physiology (IAGP)

abnormal immune system morphology (IAGP)

abnormal immune system organ morphology (IAGP)

abnormal immune system physiology (IAGP)

abnormal immunoglobulin level (IAGP)

abnormal interferon secretion (IAGP)

abnormal interleukin secretion (IAGP)

abnormal leukocyte physiology (IAGP)

abnormal lymph node cell ratio (IAGP)

abnormal lymph node germinal center morphology (IAGP)

abnormal lymph node secondary follicle morphology (IAGP)

abnormal lymph organ size (IAGP)

abnormal lymphocyte morphology (IAGP)

abnormal lymphopoiesis (IAGP)

abnormal mast cell physiology (IAGP)

abnormal mature gamma-delta T cell morphology (IAGP)

abnormal plasma cell morphology (IAGP)

abnormal platelet aggregation (IAGP)

abnormal platelet dense granule physiology (IAGP)

abnormal regulatory T cell physiology (IAGP)

abnormal salivary gland morphology (IAGP)

abnormal single-positive T cell number (IAGP)

abnormal spleen morphology (IAGP)

abnormal spleen periarteriolar lymphoid sheath morphology (IAGP)

abnormal spleen white pulp morphology (IAGP)

abnormal splenic cell ratio (IAGP)

abnormal startle reflex (IEA)

abnormal T cell activation (IAGP)

abnormal T cell differentiation (IAGP)

abnormal T cell morphology (IAGP)

abnormal T cell physiology (IAGP)

abnormal T cell proliferation (IAGP)

abnormal T cell receptor delta chain V(D)J recombination (IAGP)

abnormal T cell receptor gamma chain V-J recombination (IAGP)

abnormal T cell selection (IAGP)

abnormal T cell subpopulation ratio (IAGP)

abnormal T-helper 2 cell morphology (IAGP)

abnormal T-helper 2 physiology (IAGP)

abnormal thrombosis (IAGP)

abnormal thymocyte activation (IAGP)

abnormal thymus cell ratio (IAGP)

abnormal thymus development (IAGP)

abnormal vitreous body morphology (IEA)

absent CD4-positive, alpha-beta T cells (IAGP)

absent CD8-positive, alpha-beta T cells (IAGP)

absent mature gamma-delta T cells (IAGP)

absent T cells (IAGP)

albuminuria (IAGP)

arrested T cell differentiation (IAGP)

chronic inflammation (IAGP)

decreased body weight (IAGP)

decreased CD4-positive, alpha-beta T cell number (IAGP)

decreased CD8-positive, alpha-beta T cell number (IAGP)

decreased double-negative T cell number (IAGP)

decreased double-positive T cell number (IAGP)

decreased interferon-gamma secretion (IAGP)

decreased platelet aggregation (IAGP)

decreased regulatory T cell number (IAGP)

decreased T cell number (IAGP)

decreased T cell proliferation (IAGP)

decreased thymocyte number (IAGP)

enlarged lymph nodes (IAGP)

enlarged spleen (IAGP)

glomerulonephritis (IAGP)

increased activated T cell number (IAGP)

increased anti-chromatin antibody level (IAGP)

increased anti-double stranded DNA antibody level (IAGP)

increased anti-erythrocyte antigen antibody level (IAGP)

increased anti-nuclear antigen antibody level (IAGP)

increased autoantibody level (IAGP)

increased B cell number (IAGP)

increased blood urea nitrogen level (IAGP)

increased CD4-positive, alpha-beta T cell number (IAGP)

increased circulating bilirubin level (IEA)

increased double-negative T cell number (IAGP)

increased double-positive T cell number (IAGP)

increased eosinophil cell number (IAGP)

increased gamma-delta T cell number (IAGP)

increased IgE level (IAGP)

increased IgG1 level (IAGP)

increased IgM level (IAGP)

increased immunoglobulin level (IAGP)

increased inflammatory response (IAGP)

increased interferon-gamma secretion (IAGP)

increased interleukin-10 secretion (IAGP)

increased interleukin-4 secretion (IAGP)

increased mature gamma-delta T cell number (IAGP)

increased memory T cell number (IAGP)

increased plasma cell number (IAGP)

increased spleen germinal center number (IAGP)

increased spleen weight (IAGP)

increased susceptibility to autoimmune hemolytic anemia (IAGP)

increased T cell number (IAGP)

increased T cell proliferation (IAGP)

increased T-helper 2 cell number (IAGP)

kidney inflammation (IAGP)

liver inflammation (IAGP)

lung inflammation (IAGP)

pancreas fibrosis (IAGP)

pancreas inflammation (IAGP)

phlebitis (IAGP)

premature death (IAGP)

renal fibrosis (IAGP)

renal glomerular immunoglobulin deposits (IAGP)

salivary gland inflammation (IAGP)

small thymus (IAGP)

spleen hyperplasia (IAGP)

thymus hypoplasia (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	MGDs mouse GO annotations	MGD data from the GO Consortium
2.	MGD IEA	MGD IEA
3.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
6.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:9489702	PMID:9729044	PMID:10204488	PMID:10349636	PMID:10712938	PMID:10843385	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11389024	PMID:11457888
PMID:11841396	PMID:11901197	PMID:12065839	PMID:12065840	PMID:12077228	PMID:12477932	PMID:12570875	PMID:12626544	PMID:12807480	PMID:12871507	PMID:12932362	PMID:12953098
PMID:12970761	PMID:14610273	PMID:14635057	PMID:14685278	PMID:14688337	PMID:14696041	PMID:14764585	PMID:14996932	PMID:15153499	PMID:15238603	PMID:15372077	PMID:15470052
PMID:15477348	PMID:15477350	PMID:15485632	PMID:15489334	PMID:15549729	PMID:15719364	PMID:15745852	PMID:15795236	PMID:15886326	PMID:15894276	PMID:15899851	PMID:15976034
PMID:15985541	PMID:16002666	PMID:16102570	PMID:16141072	PMID:16141073	PMID:16291591	PMID:16380508	PMID:16456545	PMID:16460687	PMID:16602821	PMID:16709842	PMID:16878135
PMID:16887989	PMID:17081783	PMID:17277139	PMID:17374738	PMID:17420272	PMID:17579183	PMID:17918199	PMID:17938199	PMID:18209052	PMID:18322174	PMID:18343609	PMID:18464161
PMID:18539897	PMID:18645037	PMID:18826392	PMID:19133747	PMID:19228948	PMID:19234162	PMID:19380761	PMID:19380777	PMID:19380807	PMID:19403707	PMID:19449311	PMID:19494314
PMID:19592646	PMID:19592663	PMID:19667175	PMID:19682930	PMID:19701892	PMID:19795417	PMID:20010844	PMID:20107804	PMID:20130215	PMID:20133676	PMID:20498282	PMID:20592278
PMID:20606011	PMID:20723025	PMID:20837489	PMID:21267068	PMID:21303848	PMID:21487392	PMID:21677750	PMID:21844384	PMID:21873635	PMID:22382685	PMID:22561606	PMID:22566687
PMID:22732588	PMID:22922362	PMID:22984075	PMID:23209318	PMID:23240581	PMID:23401587	PMID:23407547	PMID:23443658	PMID:23776175	PMID:23793062	PMID:23825558	PMID:24218622
PMID:24222714	PMID:24265393	PMID:24523509	PMID:24584089	PMID:24595757	PMID:24978613	PMID:25425573	PMID:25455592	PMID:25683713	PMID:25847946	PMID:26034173	PMID:26121028
PMID:26715756	PMID:26936881	PMID:27480037	PMID:27500644	PMID:27505889	PMID:27721430	PMID:28063403	PMID:28538176	PMID:28628091	PMID:28965845	PMID:29440364	PMID:29902238
PMID:29915297	PMID:31135971	PMID:31611699	PMID:31911947	PMID:32727906	PMID:33661938	PMID:33912184	PMID:34161759	PMID:34862403	PMID:36569841

Genomics

Comparative Map Data

Lat
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	125,962,999 - 125,968,877 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	125,962,996 - 125,968,742 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	126,363,827 - 126,369,705 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	126,363,824 - 126,369,570 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	133,507,341 - 133,513,048 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	126,154,975 - 126,160,682 (-)	NCBI		MGSCv36	mm8
Celera	7	126,216,064 - 126,221,729 (-)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI

LAT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	28,984,803 - 28,990,784 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	16	28,984,826 - 28,990,784 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	28,996,124 - 29,002,105 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	28,903,648 - 28,909,605 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	28,904,161 - 28,909,595	NCBI
Celera	16	27,951,162 - 27,957,119 (+)	NCBI		Celera
Cytogenetic Map	16	p11.2	NCBI
HuRef	16	26,864,020 - 26,869,977 (+)	NCBI		HuRef
CHM1_1	16	30,007,898 - 30,013,855 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	29,265,918 - 29,271,899 (+)	NCBI		T2T-CHM13v2.0

Lat
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	180,936,536 - 180,941,561 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	180,936,534 - 180,941,578 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	189,267,600 - 189,272,611 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	1	196,453,644 - 196,458,655 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	1	189,141,053 - 189,146,078 (-)	NCBI	Rnor_WKY
Rnor_6.0	1	197,765,644 - 197,770,669 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	197,765,644 - 197,770,669 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	204,747,718 - 204,752,745 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	185,450,155 - 185,455,180 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	185,600,035 - 185,605,061 (-)	NCBI
Celera	1	178,597,456 - 178,602,481 (-)	NCBI		Celera
Cytogenetic Map	1	q36	NCBI

Lat
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955493	6,499,311 - 6,507,543 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955493	6,501,504 - 6,506,089 (-)	NCBI	ChiLan1.0	ChiLan1.0

LAT
(Pan paniscus - bonobo/pygmy chimpanzee)

No map positions available.

LAT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	18,458,985 - 18,462,463 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	18,459,061 - 18,462,694 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	20,035,910 - 20,040,929 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	18,593,687 - 18,598,682 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	6	18,393,170 - 18,398,180 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	18,307,953 - 18,312,955 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	18,624,382 - 18,629,399 (+)	NCBI		UU_Cfam_GSD_1.0

Lat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	123,661,385 - 123,667,218 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	11,760,840 - 11,764,397 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936501	11,759,245 - 11,764,693 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LAT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	18,639,151 - 18,644,348 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	18,638,992 - 18,644,353 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	18,825,117 - 18,830,929 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LAT
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	26,079,387 - 26,084,823 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	26,079,383 - 26,084,787 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	3,542,476 - 3,548,413 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lat
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	12,795,104 - 12,799,410 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	12,795,104 - 12,799,496 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	140
Count of miRNA genes:	130
Interacting mature miRNAs:	136
Transcripts:	ENSMUST00000032997
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25314307	Mlh1fc2_m	MLH1 foci count 2 (mouse)					7	6502999	133501729	Mouse
12792978	Fbmd3_m	femoral bone mineral density 3, females only (mouse)					7	7050288	142367832	Mouse
1301158	Eae4_m	susceptibility to experimental allergic encephalomyelitis 4 (mouse)			Not determined		7	19147398	141919804	Mouse
27226751	Femd5_m	femur midshaft diameter 5, 10 week (mouse)					7	53249748	143153737	Mouse
27226778	Femd11_m	femur midshaft diameter 11, 16 week (mouse)					7	56949748	134001729	Mouse
26884440	Sklq4_m	skull length QTL 4, 5 week (mouse)					7	65249748	126499172	Mouse
27095933	Ulnl3_m	ulna length 3, 5 week (mouse)					7	73149748	143153737	Mouse
26884398	Humsd6_m	humerus midshaft diameter 6, 16 week (mouse)					7	78649748	136901729	Mouse
27095930	Ulnl10_m	ulna length 10, 16 week (mouse)					7	80849748	126699172	Mouse
27095903	Scvln10_m	sacral vertebrae length 2, 10 week (mouse)					7	81449748	126499172	Mouse
27226765	Tibl18_m	tibia length 18, 16 week (mouse)					7	81849748	126499172	Mouse
27226769	Tibl12_m	tibia length 12, 10 week (mouse)					7	87249208	126499172	Mouse
27226790	Feml15_m	femur length 15, 10 week (mouse)					7	87249208	126499172	Mouse
1300528	Ssial3_m	susceptibility to sialadenitis 3 (mouse)			Not determined		7	93391848	127392041	Mouse
1301478	Eae26_m	susceptibility to experimental allergic encephalomyelitis 26 (mouse)			Not determined		7	98164922	132165010	Mouse
13524850	Asrq7_m	acoustic startle response 7 (mouse)					7	98394974	132394974	Mouse
10412104	Tons2_m	tongue size 2 (mouse)			Not determined		7	99837716	133837716	Mouse
11039524	Tbbr3_m	Trypanosoma brucei brucei response 3 (mouse)					7	100750722	134750843	Mouse
1301447	Fembm3_m	femoral bone morphometry 3 (mouse)			Not determined		7	100993261	134993342	Mouse
1357460	Vtbt4_m	vertebral trabecular bone trait 4 (mouse)			Not determined		7	101693381	135693530	Mouse
1301105	Cfld4_m	cystic fibrosis lung disease 4 (mouse)			Not determined		7	101693381	135693530	Mouse
1300721	Cfbw3_m	cystic fibrosis body weight 3 (mouse)			Not determined		7	101693381	135693530	Mouse
4142312	Nilac4_m	nicotine induced locomotor activity 4 (mouse)			Not determined		7	102485219	136485380	Mouse
5491192	Mobq1_m	multigenic obesity QTL 1 (mouse)			Not determined		7	105250663	139250811	Mouse
13524852	Asrq7a_m	acoustic startle response 7a (mouse)					7	105350008	139350008	Mouse
14700684	Civq1_m	cerebral infarct volume QTL 1 (mouse)					7	109707335	143707335	Mouse
14700687	Civq5_m	cerebral infarct volume QTL 5 (mouse)					7	109707335	143707335	Mouse
14700688	Civq6_m	cerebral infarct volume QTL 6 (mouse)					7	109707335	143707335	Mouse
11059562	Lmr21b_m	leishmaniasis resistance 21b (mouse)					7	110967235	144967336	Mouse
10402499	Lmr21_m	leishmaniasis resistance 21 (mouse)			Not determined		7	110967235	144967336	Mouse
1302032	Alcp12_m	alcohol preference locus 12 (mouse)			Not determined		7	111166122	144995196	Mouse
1301898	Alcp14_m	alcohol preference locus 14 (mouse)			Not determined		7	111166122	144995196	Mouse
1300670	Sluc19_m	susceptibility to lung cancer 19 (mouse)			Not determined		7	111166122	144995196	Mouse
4142444	Femwf5_m	femur work to failure 5 (mouse)			Not determined			112552248	144995196	Mouse
1300747	Skts2_m	skin tumor susceptibility 2 (mouse)			Not determined		7	112922733	144995196	Mouse
38501072	Stsl7_m	Salmonella typhimurium susceptibility locus 7 (mouse)					7	115699235	128501724	Mouse
1300677	Bmd9_m	bone mineral density 9 (mouse)			Not determined		7	116634089	144995196	Mouse
15092059	Wogrme1_m	week one growth rate, maternal effect 1 (mouse)					7	117199227	134101729	Mouse
11059561	Lmr21a_m	leishmaniasis resistance 21a (mouse)					7	117750722	127967336	Mouse
1357711	Adbg1_m	adult body growth 1 (mouse)			Not determined		7	118693381	144398314	Mouse
1301773	Stheal7_m	soft tissue heal 7 (mouse)			Not determined		7	119132573	144995196	Mouse
1357613	Bsbob2_m	BSB obesity 2 (mouse)			Not determined		7	122250663	128819324	Mouse
1301903	Tlsm1_m	thymic lymphoma susceptible 1 (mouse)			Not determined		7	122250663	135170901	Mouse
38501066	Tip2_m	tuberculosis immunophenotype 2, spleen CFU (mouse)					7	124299223	126899172	Mouse
4141945	Il4ppq_m	IL-4 producing potential QTL (mouse)			Not determined		7	124513662	128819324	Mouse

Markers in Region

AF036907

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	7	126,363,920 - 126,364,028	UniSTS	GRCm38
MGSCv37	7	133,507,434 - 133,507,542	UniSTS	GRCm37
Celera	7	126,216,157 - 126,216,265	UniSTS
Cytogenetic Map	7	F3	UniSTS
Whitehead/MRC_RH	7	1287.9	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_010689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006507396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006507397	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006507398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_030242172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC125322	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF036907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ438435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK088763	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK090369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK134003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC052340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BE947351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000032997 ⟹ ENSMUSP00000032997

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	125,962,999 - 125,968,706 (-)	Ensembl
GRCm38.p6 Ensembl	7	126,363,827 - 126,369,534 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000205398

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	125,966,690 - 125,968,742 (-)	Ensembl
GRCm38.p6 Ensembl	7	126,367,518 - 126,369,570 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000205426

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	125,963,076 - 125,964,058 (-)	Ensembl
GRCm38.p6 Ensembl	7	126,363,904 - 126,364,886 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000205642 ⟹ ENSMUSP00000146191

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	125,967,271 - 125,968,666 (-)	Ensembl
GRCm38.p6 Ensembl	7	126,368,099 - 126,369,494 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000206731

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	125,967,829 - 125,968,512 (-)	Ensembl
GRCm38.p6 Ensembl	7	126,368,657 - 126,369,340 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000206793 ⟹ ENSMUSP00000145773

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	7	125,962,996 - 125,968,713 (-)	Ensembl
GRCm38.p6 Ensembl	7	126,363,824 - 126,369,541 (-)	Ensembl

RefSeq Acc Id:

NM_010689 ⟹ NP_034819

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	125,962,999 - 125,968,740 (-)	NCBI
GRCm38	7	126,363,827 - 126,369,568 (-)	NCBI
MGSCv37	7	133,507,341 - 133,513,048 (-)	RGD
Celera	7	126,216,064 - 126,221,729 (-)	RGD
cM Map	7		ENTREZGENE

Sequence:

show sequence

AGCTTCCTGTCGCACGCGGTGGTGAGCAGGAGAGGCAGGCGGGGAGCAAGAAAGGGGCAGGTAC
AGCTGGGCACGGGGATCGTGCAGCTGGTAGCTGGGGCACGGGCCCCAGCTCTGGCTCTGGGGCG
AGCACCTTTCCAGAGCCAACACTGCTCTCAACTCAGTCCAGCAAGAGAGGGGAGCCATCCAGCC
CCGAAAGGATACGGCTGCCTACTGCCGGGCGGATCCCAGGCTGGAGCCCGCTTGGTCCCATACC
CCTGCTGCCACTCTGTCTCGAGGGGCTGCAGTGCAGCAGGGCCTGTGGCAGGTGCTCTGCAGAT
GGAAGCAGACGCCTTGAGCCCGGTGGGGCTGGGCCTCCTGCTGCTGCCCTTCTTGGTCACGCTC
CTGGCTGCCCTGTGCGTGCGCTGCCGTGAGTTGCCAGTCTCCTATGACAGCACTTCCACAGAGA
GTTTGTACCCAAGAAGCATCCTCATCAAGCCACCTCAAATAACCGTCCCCCGAACACCTGCTGT
TTCCTACCCTCTAGTCACTTCCTTCCCACCCCTGAGGCAGCCAGACCTGCTCCCCATCCCGAGA
TCCCCACAGCCCCTTGGGGGTTCCCATCGGATGCCATCTTCCCAGCAGAATTCAGATGATGCCA
ACAGTGTGGCAAGCTACGAGAACCAGGAGCCAGCCTGTAAGAATGTGGATGCAGATGAGGATGA
AGACGACTATCCCAACGGCTACCTAGTGGTGCTGCCTGACAGTAGTCCTGCTGCCGTCCCTGTT
GTCTCCTCTGCTCCTGTGCCTAGCAACCCTGACCTTGGAGACAGTGCCTTCTCTGTGGAGTCGT
GTGAAGATTACGTGAATGTTCCTGAGAGTGAGGAGAGCGCAGAGGCGTCTCTGGATGGGAGCCG
GGAGTATGTGAATGTGTCCCCAGAGCAGCAGCCAGTGACCAGGGCTGAGCTGGCCTCTGTGAAC
TCCCAGGAGGTGGAAGACGAAGGAGAAGAGGAAGGGGTGGATGGAGAGGAAGCTCCTGACTATG
AGAATCTGCAGGAGCTTAACTGAAAGCCTACTGCAGCTGTCTGTCCTGAAACTGGACTTGCTGG
GGTGTCGCTAAGAGGATCCCATTTGACCTCTGCCTTGCCACAGCCTGAGAATCTTCCCCTAACT
TATTGTCACTTTGGGGTCCAGTCTGTGTCCCCAATATTCTGTACCTTCTGATAAAGCCTGAGAA
TGAATCTGGTTCCAGCCAGACCATGTCATGGAATAAAGGCCATGTGACATAAAAAAAAAAAAAA
A

hide sequence

RefSeq Acc Id:

XM_006507396 ⟹ XP_006507459

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	125,962,999 - 125,968,877 (-)	NCBI
GRCm38	7	126,363,827 - 126,369,705 (-)	NCBI

Sequence:

show sequence

GCCTCATCCTGCAGCCTTAGACCCTTCCTCCACACAGTCCCTCTGCCTCCTCCCCCTTCCCACA
ACTGGGTGGGGGTGAGTGGGCAGGGGGCAGGCTCAGCCTGCTGAGCAGCCTGATGATTTCCTGC
CCTCACCACAGCTTCCTGTCGCACGCGGTGGTGAGCAGGAGAGGCAGGCGGGGAGCAAGAAAGG
GGCAGGTACAGCTGGGCACGGGGATCGTGCAGCTGGTAGCTGGGGCACGGGCCCCAGCTCTGGC
TCTGGGGCGAGCACCTTTCCAGAGCCAACACTGCTCTCAACTCAGTCCAGCAAGAGAGGGGAGC
CATCCAGCCCCGAAAGGATACGGCTGCCTACTGCCGGGCGGATCCCAGGCTGGAGCCCGCTTGG
TCCCATACCCCTGCTGCCACTCTGTCTCGAGGGGCTGCAGTGCAGCAGGGCCTGTGGCAGGTGC
TCTGCAGATGGAAGCAGACGCCTTGAGCCCGGTGGGGCTGGGCCTCCTGCTGCTGCCCTTCTTG
GTCACGCTCCTGGCTGCCCTGTGCGTGCGCTGCCGTGAGTTGCCAGTCTCCTATGACAGCACTT
CCACAGAGAGTTTGTACCCAAGAAGCATCCTCATCAAGCCACCTCAAATAACCGTCCCCCGAAC
ACCTGCTGTTTCCTACCCTCTAGTCACTTCCTTCCCACCCCTGAGGCAGCCAGACCTGCTCCCC
ATCCCGAGATCCCCACAGCCCCTTGGGGGTTCCCATCGGATGCCATCTTCCCAGCAGAATTCAG
ATGATGAGCCAGCCTGTAAGAATGTGGATGCAGATGAGGATGAAGACGACTATCCCAACGGCTA
CCTAGTGGTGCTGCCTGACAGTAGTCCTGCTGCCGTCCCTGTTGTCTCCTCTGCTCCTGTGCCT
AGCAACCCTGACCTTGGAGACAGTGCCTTCTCTGTGGAGTCGTGTGAAGATTACGTGAATGTTC
CTGAGAGTGAGGAGAGCGCAGAGGCGTCTCTGGATGGGAGCCGGGAGTATGTGAATGTGTCCCC
AGAGCAGCAGCCAGTGACCAGGGCTGAGCTGGCCTCTGTGAACTCCCAGGAGGTGGAAGACGAA
GGAGAAGAGGAAGGGGTGGATGGAGAGGAAGCTCCTGACTATGAGAATCTGCAGGAGCTTAACT
GAAAGCCTACTGCAGCTGTCTGTCCTGAAACTGGACTTGCTGGGGTGTCGCTAAGAGGATCCCA
TTTGACCTCTGCCTTGCCACAGCCTGAGAATCTTCCCCTAACTTATTGTCACTTTGGGGTCCAG
TCTGTGTCCCCAATATTCTGTACCTTCTGATAAAGCCTGAGAATGAATCTGGTTCCAGCCAGAC
CATGTCATGGAATAAAGGCCATGTGACATAAA

hide sequence

RefSeq Acc Id:

XM_006507397 ⟹ XP_006507460

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	125,962,999 - 125,968,760 (-)	NCBI
GRCm38	7	126,363,827 - 126,369,585 (-)	NCBI

Sequence:

show sequence

TGATTTCCTGCCCTCACCACAGCTTCCTGTCGCACGCGGTGGTGAGCAGGAGAGGCAGGCGGGG
AGCAAGAAAGGGGCAGGTACAGCTGGGCACGGGGATCGTGCAGCTGGTAGCTGGGGCACGGGCC
CCAGCTCTGGCTCTGGGGCGAGCACCTTTCCAGAGCCAACACTGCTCTCAACTCAGTCCAGCAA
GAGAGGGGAGCCATCCAGCCCCGAAAGGATACGGCTGCCTACTGCCGGGCGGATCCCAGGCTGG
AGCCCGCTTGGTCCCATACCCCTGCTGCCACTCTGTCTCGAGGGGCTGCAGTGCAGCAGGGCCT
GTGGCAGGTGCTCTGCAGATGGAAGCAGACGCCTTGAGCCCGGTGGGGCTGGGCCTCCTGCTGC
TGCCCTTCTTGGTCACGCTCCTGGCTGCCCTGTGCGTGCGCTGCCGTGAGTTGCCAGTCTCCTA
TGACAGCACTTCCACAGAGAGTTTGTACCCAAGAAGCATCCTCATCAAGCCACCTCTCACTTCC
TTCCCACCCCTGAGGCAGCCAGACCTGCTCCCCATCCCGAGATCCCCACAGCCCCTTGGGGGTT
CCCATCGGATGCCATCTTCCCAGCAGAATTCAGATGATGCCAACAGTGTGGCAAGCTACGAGAA
CCAGGAGCCAGCCTGTAAGAATGTGGATGCAGATGAGGATGAAGACGACTATCCCAACGGCTAC
CTAGTGGTGCTGCCTGACAGTAGTCCTGCTGCCGTCCCTGTTGTCTCCTCTGCTCCTGTGCCTA
GCAACCCTGACCTTGGAGACAGTGCCTTCTCTGTGGAGTCGTGTGAAGATTACGTGAATGTTCC
TGAGAGTGAGGAGAGCGCAGAGGCGTCTCTGGATGGGAGCCGGGAGTATGTGAATGTGTCCCCA
GAGCAGCAGCCAGTGACCAGGGCTGAGCTGGCCTCTGTGAACTCCCAGGAGGTGGAAGACGAAG
GAGAAGAGGAAGGGGTGGATGGAGAGGAAGCTCCTGACTATGAGAATCTGCAGGAGCTTAACTG
AAAGCCTACTGCAGCTGTCTGTCCTGAAACTGGACTTGCTGGGGTGTCGCTAAGAGGATCCCAT
TTGACCTCTGCCTTGCCACAGCCTGAGAATCTTCCCCTAACTTATTGTCACTTTGGGGTCCAGT
CTGTGTCCCCAATATTCTGTACCTTCTGATAAAGCCTGAGAATGAATCTGGTTCCAGCCAGACC
ATGTCATGGAATAAAGGCCATGTGACATAAA

hide sequence

RefSeq Acc Id:

XM_006507398 ⟹ XP_006507461

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	125,962,999 - 125,968,761 (-)	NCBI
GRCm38	7	126,363,827 - 126,369,587 (-)	NCBI

Sequence:

show sequence

ATGATTTCCTGCCCTCACCACAGCTTCCTGTCGCACGCGGTGGTGAGCAGGAGAGGCAGGCGGG
GAGCAAGAAAGGGGCAGGTACAGCTGGGCACGGGGATCGTGCAGCTGGTAGCTGGGGCACGGGC
CCCAGCTCTGGCTCTGGGGCGAGCACCTTTCCAGAGCCAACACTGCTCTCAACTCAGTCCAGCA
AGAGAGGGGAGCCATCCAGCCCCGAAAGGATACGGCTGCCTACTGCCGGGCGGATCCCAGGCTG
GAGCCCGCTTGGTCCCATACCCCTGCTGCCACTCTGTCTCGAGGGGCTGCAGTGCAGCAGGGCC
TGTGGCAGGTGCTCTGCAGATGGAAGCAGACGCCTTGAGCCCGGTGGGGCTGGGCCTCCTGCTG
CTGCCCTTCTTGGTCACGCTCCTGGCTGCCCTGTGCGTGCGCTGCCGTGAGTTGCCAGTCTCCT
ATGACAGCACTTCCACAGAGAGTCACTTCCTTCCCACCCCTGAGGCAGCCAGACCTGCTCCCCA
TCCCGAGATCCCCACAGCCCCTTGGGGGTTCCCATCGGATGCCATCTTCCCAGCAGAATTCAGA
TGATGCCAACAGTGTGGCAAGCTACGAGAACCAGGAGCCAGCCTGTAAGAATGTGGATGCAGAT
GAGGATGAAGACGACTATCCCAACGGCTACCTAGTGGTGCTGCCTGACAGTAGTCCTGCTGCCG
TCCCTGTTGTCTCCTCTGCTCCTGTGCCTAGCAACCCTGACCTTGGAGACAGTGCCTTCTCTGT
GGAGTCGTGTGAAGATTACGTGAATGTTCCTGAGAGTGAGGAGAGCGCAGAGGCGTCTCTGGAT
GGGAGCCGGGAGTATGTGAATGTGTCCCCAGAGCAGCAGCCAGTGACCAGGGCTGAGCTGGCCT
CTGTGAACTCCCAGGAGGTGGAAGACGAAGGAGAAGAGGAAGGGGTGGATGGAGAGGAAGCTCC
TGACTATGAGAATCTGCAGGAGCTTAACTGAAAGCCTACTGCAGCTGTCTGTCCTGAAACTGGA
CTTGCTGGGGTGTCGCTAAGAGGATCCCATTTGACCTCTGCCTTGCCACAGCCTGAGAATCTTC
CCCTAACTTATTGTCACTTTGGGGTCCAGTCTGTGTCCCCAATATTCTGTACCTTCTGATAAAG
CCTGAGAATGAATCTGGTTCCAGCCAGACCATGTCATGGAATAAAGGCCATGTGACATAAA

hide sequence

RefSeq Acc Id:

XM_030242172 ⟹ XP_030098032

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	7	125,963,846 - 125,968,877 (-)	NCBI
GRCm38	7	126,364,675 - 126,369,705 (-)	NCBI

Sequence:

show sequence

GCCTCATCCTGCAGCCTTAGACCCTTCCTCCACACAGTCCCTCTGCCTCCTCCCCCTTCCCACA
ACTGGGTGGGGGTGAGTGGGCAGGGGGCAGGCTCAGCCTGCTGAGCAGCCTGATGATTTCCTGC
CCTCACCACAGCTTCCTGTCGCACGCGGTGGTGAGCAGGAGAGGCAGGCGGGGAGCAAGAAAGG
GGCAGGTACAGCTGGGCACGGGGATCGTGCAGCTGGTAGCTGGGGCACGGGCCCCAGCTCTGGC
TCTGGGGCGAGCACCTTTCCAGAGCCAACACTGCTCTCAACTCAGTCCAGCAAGAGAGGGGAGC
CATCCAGCCCCGAAAGGATACGGCTGCCTACTGCCGGGCGGATCCCAGGCTGGAGCCCGCTTGG
TCCCATACCCCTGCTGCCACTCTGTCTCGAGGGGCTGCAGTGCAGCAGGGCCTGTGGCAGGTGC
TCTGCAGATGGAAGCAGACGCCTTGAGCCCGGTGGGGCTGGGCCTCCTGCTGCTGCCCTTCTTG
GTCACGCTCCTGGCTGCCCTGTGCGTGCGCTGCCGTGAGTTGCCAGTCTCCTATGACAGCACTT
CCACAGAGAGTTTGTACCCAAGAAGCATCCTCATCAAGCCACCTCAAATAACCGTCCCCCGAAC
ACCTGCTGTTTCCTACCCTCTAGTCACTTCCTTCCCACCCCTGAGGCAGCCAGACCTGCTCCCC
ATCCCGAGATCCCCACAGCCCCTTGGGGGTTCCCATCGGATGCCATCTTCCCAGCAGAATTCAG
ATGATGCCAACAGTGTGGCAAGCTACGAGAACCAGGAGCCAGCCTGTAAGAATGTGGATGCAGA
TGAGGATGAAGACGACTATCCCAACGGCTACCTAGTGGTGCTGCCTGACAGTAGTCCTGCTGCC
GTCCCTGTTGTCTCCTCTGCTCCTGTGCCTAGCAACCCTGACCTTGGAGACAGTGCCTTCTCTG
AGGCTCTGGTCCTGGCTCTCCATCCACCTCCATGGCCCTTGCCCTGCCCAGGCTTCTTCTCCCC
TCGCTTTTCCTGAATATTCTCTCTATATTGTGAGTCTGCCTGGGGGTTGTGTTAGGAGACTTAG
ATGTCTGAGCCGGGGGTGGGAGGTGTCTCTGGGGAAC

hide sequence

Protein Sequences


Protein RefSeqs	NP_034819	(Get FASTA)	NCBI Sequence Viewer
	XP_006507459	(Get FASTA)	NCBI Sequence Viewer
	XP_006507460	(Get FASTA)	NCBI Sequence Viewer
	XP_006507461	(Get FASTA)	NCBI Sequence Viewer
	XP_030098032	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC40054	(Get FASTA)	NCBI Sequence Viewer
	AAH52340	(Get FASTA)	NCBI Sequence Viewer
	BAC40554	(Get FASTA)	NCBI Sequence Viewer
	BAE21976	(Get FASTA)	NCBI Sequence Viewer
	CAD27390	(Get FASTA)	NCBI Sequence Viewer
	EDL17345	(Get FASTA)	NCBI Sequence Viewer
	EDL17346	(Get FASTA)	NCBI Sequence Viewer
	O54957	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_034819 ⟸ NM_010689
- Peptide Label:	precursor
- UniProtKB:	O54957 (UniProtKB/Swiss-Prot), Q546H1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEADALSPVGLGLLLLPFLVTLLAALCVRCRELPVSYDSTSTESLYPRSILIKPPQITVPRTPA VSYPLVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSQQNSDDANSVASYENQEPACKNVDADED EDDYPNGYLVVLPDSSPAAVPVVSSAPVPSNPDLGDSAFSVESCEDYVNVPESEESAEASLDGS REYVNVSPEQQPVTRAELASVNSQEVEDEGEEEGVDGEEAPDYENLQELN hide sequence

RefSeq Acc Id:

XP_006507460 ⟸ XM_006507397

- Peptide Label:

isoform X2

- Sequence:

show sequence

MEADALSPVGLGLLLLPFLVTLLAALCVRCRELPVSYDSTSTESLYPRSILIKPPLTSFPPLRQ
PDLLPIPRSPQPLGGSHRMPSSQQNSDDANSVASYENQEPACKNVDADEDEDDYPNGYLVVLPD
SSPAAVPVVSSAPVPSNPDLGDSAFSVESCEDYVNVPESEESAEASLDGSREYVNVSPEQQPVT
RAELASVNSQEVEDEGEEEGVDGEEAPDYENLQELN

hide sequence

RefSeq Acc Id:

XP_006507459 ⟸ XM_006507396

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEADALSPVGLGLLLLPFLVTLLAALCVRCRELPVSYDSTSTESLYPRSILIKPPQITVPRTPA
VSYPLVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSQQNSDDEPACKNVDADEDEDDYPNGYLV
VLPDSSPAAVPVVSSAPVPSNPDLGDSAFSVESCEDYVNVPESEESAEASLDGSREYVNVSPEQ
QPVTRAELASVNSQEVEDEGEEEGVDGEEAPDYENLQELN

hide sequence

RefSeq Acc Id:	XP_006507461 ⟸ XM_006507398
- Peptide Label:	isoform X4
- Sequence:	show sequence MTALPQRVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSQQNSDDANSVASYENQEPACKNVDAD EDEDDYPNGYLVVLPDSSPAAVPVVSSAPVPSNPDLGDSAFSVESCEDYVNVPESEESAEASLD GSREYVNVSPEQQPVTRAELASVNSQEVEDEGEEEGVDGEEAPDYENLQELN hide sequence

RefSeq Acc Id:	XP_030098032 ⟸ XM_030242172
- Peptide Label:	isoform X3

RefSeq Acc Id:

ENSMUSP00000032997 ⟸ ENSMUST00000032997

RefSeq Acc Id:

ENSMUSP00000145773 ⟸ ENSMUST00000206793

RefSeq Acc Id:

ENSMUSP00000146191 ⟸ ENSMUST00000205642

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O54957-F1-model_v2	AlphaFold	O54957	1-242	view protein structure

Promoters

RGD ID:

8665523

Promoter ID:

EPDNEW_M10793

Type:

initiation region

Name:

Lat_1

Description:

Mus musculus linker for activation of T cells , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	7	126,369,570 - 126,369,630	EPDNEW

RGD ID:

6841407

Promoter ID:

MM_KWN:52656

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Lung, Spleen

Transcripts:

ENSMUST00000032997

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	7	133,512,821 - 133,513,397 (-)	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1342293	AgrOrtholog
Ensembl Genes	ENSMUSG00000030742	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000032997	ENTREZGENE
	ENSMUSP00000032997.7	UniProtKB/Swiss-Prot
	ENSMUSP00000145773.2	UniProtKB/TrEMBL
	ENSMUSP00000146191.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000032997	ENTREZGENE
	ENSMUST00000032997.8	UniProtKB/Swiss-Prot
	ENSMUST00000205642.2	UniProtKB/TrEMBL
	ENSMUST00000206793.2	UniProtKB/TrEMBL
InterPro	Linker_for_activat_Tcells_prot	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:16797	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1342293	ENTREZGENE
NCBI Gene	16797	ENTREZGENE
PANTHER	LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR15586	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	LAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Lat	PhenoGen
PRINTS	LATPROTEIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0U1RP03_MOUSE	UniProtKB/TrEMBL
	A0A0U1RQ02_MOUSE	UniProtKB/TrEMBL
	LAT_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q546H1	ENTREZGENE, UniProtKB/TrEMBL
	Q80UR6_MOUSE	UniProtKB/TrEMBL
	Q8C2E5_MOUSE	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)

Mammalian Phenotype