NFE2L2 (NFE2 like bZIP transcription factor 2) - Rat Genome Database

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Gene: NFE2L2 (NFE2 like bZIP transcription factor 2) Homo sapiens
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Symbol: NFE2L2
Name: NFE2 like bZIP transcription factor 2
RGD ID: 734431
HGNC Page HGNC:7782
Description: Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; molecular condensate scaffold activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of programmed cell death; positive regulation of macromolecule biosynthetic process; and proteasomal protein catabolic process. Located in several cellular components, including Golgi apparatus; centrosome; and nucleoplasm. Part of RNA polymerase II transcription regulator complex. Is active in mediator complex. Implicated in Alzheimer's disease; cataract; hepatocellular carcinoma; macular degeneration; and tuberculosis. Biomarker of amyotrophic lateral sclerosis; asthma; chronic obstructive pulmonary disease (multiple); obesity; and visceral leishmaniasis.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: HEBP1; IMDDHH; NF-E2-related factor 2; NFE2-related factor 2; Nrf-2; NRF2; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382177,230,303 - 177,264,727 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2177,218,667 - 177,392,756 (-)EnsemblGRCh38hg38GRCh38
GRCh372178,095,031 - 178,129,455 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362177,803,282 - 177,837,663 (-)NCBINCBI36Build 36hg18NCBI36
Build 342177,920,542 - 177,954,924NCBI
Celera2171,697,459 - 171,732,295 (-)NCBICelera
Cytogenetic Map2q31.2NCBI
HuRef2169,966,324 - 170,001,125 (-)NCBIHuRef
CHM1_12178,100,863 - 178,135,685 (-)NCBICHM1_1
T2T-CHM13v2.02177,712,539 - 177,746,971 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model