Tpp2 (tripeptidyl peptidase II) - Rat Genome Database

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Gene: Tpp2 (tripeptidyl peptidase II) Mus musculus
Analyze
Symbol: Tpp2
Name: tripeptidyl peptidase II
RGD ID: 734319
MGI Page MGI
Description: Predicted to enable exopeptidase activity; identical protein binding activity; and peptide binding activity. Predicted to be involved in intracellular amino acid homeostasis and protein catabolic process. Predicted to be located in nuclear body. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human TPP2 (tripeptidyl peptidase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: T; TPP-2; TPP-II; TppII; tripeptidyl aminopeptidase; tripeptidyl-peptidase 2; tripeptidyl-peptidase II
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39143,973,130 - 44,042,160 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl143,972,807 - 44,042,160 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38143,933,970 - 44,003,000 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl143,933,647 - 44,003,000 (+)Ensemblmm10GRCm38
MGSCv37143,990,852 - 44,059,816 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36143,878,553 - 43,947,517 (+)NCBIMGSCv36mm8
Celera144,277,065 - 44,346,020 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map123.5NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (ISO)
2-bromohexadecanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
5-fluorouracil  (EXP,ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
bisphenol AF  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
cisplatin  (EXP)
crocidolite asbestos  (EXP)
dibenzo[a,l]pyrene  (EXP)
Dibutyl phosphate  (ISO)
dichlorine  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
etoposide  (EXP,ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
furfural  (ISO)
geldanamycin  (ISO)
gentamycin  (ISO)
glyphosate  (EXP)
hydrogen peroxide  (ISO)
hydroxyurea  (EXP,ISO)
hypochlorous acid  (EXP)
ivermectin  (ISO)
L-methionine  (EXP)
lead(0)  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methidathion  (EXP)
mifepristone  (ISO)
N-nitrosodiethylamine  (ISO)
nicotine  (EXP)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (EXP)
propanal  (ISO)
rotenone  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
sirolimus  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP,ISO)
theophylline  (ISO)
thimerosal  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
torcetrapib  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
triptonide  (EXP)
vanadyl sulfate  (ISO)
wortmannin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IBA,IEA,ISO)
endoplasmic reticulum  (IEA)
nuclear body  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Tripeptidyl-peptidase II expression and activity are increased in skeletal muscle during sepsis. Wray CJ, etal., Biochem Biophys Res Commun 2002 Aug 9;296(1):41-7.
Additional References at PubMed
PMID:1682057   PMID:7998988   PMID:8661741   PMID:9108304   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273  
PMID:15782199   PMID:16141072   PMID:16141073   PMID:17088258   PMID:17357105   PMID:17932511   PMID:17967808   PMID:18056356   PMID:18362329   PMID:18822395   PMID:19351849   PMID:19539606  
PMID:19841172   PMID:21873635   PMID:22266401   PMID:23818952   PMID:25303791   PMID:25414442   PMID:28378742   PMID:28671696   PMID:30457570   PMID:30562941   PMID:32325033   PMID:37142655  
PMID:37839992   PMID:38389851  


Genomics

Comparative Map Data
Tpp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39143,973,130 - 44,042,160 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl143,972,807 - 44,042,160 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38143,933,970 - 44,003,000 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl143,933,647 - 44,003,000 (+)Ensemblmm10GRCm38
MGSCv37143,990,852 - 44,059,816 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36143,878,553 - 43,947,517 (+)NCBIMGSCv36mm8
Celera144,277,065 - 44,346,020 (+)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map123.5NCBI
TPP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813102,596,986 - 102,679,958 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13102,596,958 - 102,679,958 (+)Ensemblhg38GRCh38
GRCh3713103,249,336 - 103,332,308 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613102,047,374 - 102,129,522 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3413102,047,373 - 102,129,522NCBI
Celera1384,091,643 - 84,173,864 (+)NCBICelera
Cytogenetic Map13q33.1NCBI
HuRef1383,841,839 - 83,924,038 (+)NCBIHuRef
CHM1_113103,218,763 - 103,300,981 (+)NCBICHM1_1
T2T-CHM13v2.013101,812,992 - 101,895,917 (+)NCBIT2T-CHM13v2.0
Tpp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8953,538,788 - 53,620,253 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl953,538,313 - 53,620,251 (+)EnsemblGRCr8
mRatBN7.2946,046,712 - 46,128,157 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl946,046,632 - 46,128,157 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx954,558,681 - 54,643,682 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0959,681,484 - 59,766,488 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0957,961,710 - 58,046,719 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0950,664,048 - 50,744,803 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0950,578,868 - 50,628,943 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl950,581,234 - 50,744,803 (+)Ensemblrn6Rnor6.0
Rnor_5.0950,244,904 - 50,293,192 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0950,328,059 - 50,409,442 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4942,984,834 - 43,066,195 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera943,759,380 - 43,840,712 (+)NCBICelera
RGSC_v3.1942,986,247 - 43,067,609 (+)NCBI
Cytogenetic Map9q22NCBI
Tpp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554048,463,715 - 8,528,784 (-)Ensembl
ChiLan1.0NW_0049554048,465,877 - 8,528,372 (-)NCBIChiLan1.0ChiLan1.0
TPP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214104,113,261 - 104,195,967 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113102,781,660 - 102,863,918 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01383,756,757 - 83,838,997 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113102,892,037 - 102,974,974 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13102,892,037 - 102,974,974 (+)EnsemblpanPan2panpan1.1
TPP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12252,105,821 - 52,176,213 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2252,105,886 - 52,175,426 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2251,885,525 - 51,955,929 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02252,556,648 - 52,627,124 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2252,556,638 - 52,627,381 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12252,205,955 - 52,276,357 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02252,222,152 - 52,292,574 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02252,263,035 - 52,333,679 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tpp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945187,513,772 - 187,581,553 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364728,369,736 - 8,438,412 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364728,370,607 - 8,438,376 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1170,943,141 - 71,009,627 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11170,943,142 - 71,009,381 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21178,219,920 - 78,323,062 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TPP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1381,151,769 - 81,234,755 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl381,151,801 - 81,236,235 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604637,688,665 - 37,771,717 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tpp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247938,779,967 - 8,848,539 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247938,782,956 - 8,848,547 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Tpp2
2674 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:222
Count of miRNA genes:183
Interacting mature miRNAs:201
Transcripts:ENSMUST00000087933
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
1357524W6q14_mweight 6 weeks QTL 14 (mouse)Not determined13476013873976915Mouse
12910788Pwgrq9_mpost-weaning growth rate QTL 9 (mouse)14086800867270256Mouse
1301714Vertcling_mvertical clinging (mouse)Not determined14293803176938167Mouse
1301073Orch5_mautoimmune orchitis resistance 5 (mouse)Not determined11906535153065454Mouse
18182931Metl1_mmetabolite locus 1, pyridoxate (mouse)14127539975275399Mouse
1357651Lgq5_mlate growth QTL 5 (mouse)Not determined13476013873976915Mouse
12910786Pwgrq10_mpost-weaning growth rate QTL 10 (mouse)14086800867270256Mouse
11100001Col4a1m1_mcollagen, type IV, alpha 1 modifier 1 (mouse)12555019162946882Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1301954Lrnx11_mlearning-contextual 11 (mouse)Not determined13913280874516365Mouse
12880407V125Dq2_mvitamin D active form serum level QTL 2 (mouse)11933908153339081Mouse
1357824Estoq4_membryo survival total QTL 4 (mouse)Not determined13476013873976915Mouse
1357506W10q6_mweight 10 weeks QTL 6 (mouse)Not determined13476013873976915Mouse
4141032Wbcc1_mwhite blood cell count 1 (mouse)Not determined4225966776259667Mouse
39128207Lwq16_mliver weight QTL 16 (mouse)13476013873976915Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134760138150193871Mouse
12880409V125Dq1_mvitamin D active form serum level QTL 1 (mouse)12603916060039160Mouse
4142433Hbnr1_mHeligmosomoides bakeri nematode resistance 1 (mouse)Not determined2555019158273271Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134760138150193871Mouse
1301240Sluc15_msusceptibility to lung cancer 15 (mouse)Not determined11906535153065454Mouse
1357759W3q12_mweight 3 weeks QTL 12 (mouse)Not determined13476013873976915Mouse
14700685Civq2_mcerebral infarct volume QTL 2 (mouse)11134048245340482Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134760138150193871Mouse
1301756Pgia1_mproteoglycan induced arthritis 1 (mouse)Not determined11906535153065454Mouse
1357475w3q13_mweight 3 weeks QTL 13 (mouse)Not determined12310959173976915Mouse
12910780Pwgrq11_mpost-weaning growth rate QTL 11 (mouse)14086800867270256Mouse
1301166Thypr2_mthymocyte proliferative response 2 (mouse)Not determined14127312475273271Mouse

Markers in Region
X81323  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38144,002,335 - 44,002,490UniSTSGRCm38
MGSCv37144,059,180 - 44,059,335UniSTSGRCm37
Celera144,345,384 - 44,345,539UniSTS
Cytogenetic Map1C1.1UniSTS
Whitehead/MRC_RH1705.51UniSTS
Whitehead_YAC1 UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS
X81323  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38144,002,337 - 44,002,437UniSTSGRCm38
MGSCv37144,059,182 - 44,059,282UniSTSGRCm37
Celera144,345,386 - 44,345,486UniSTS
Cytogenetic Map1C1.1UniSTS
Whitehead/MRC_RH1705.51UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001310540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001784011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_373249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC125134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB725588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY147762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X81323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000087933   ⟹   ENSMUSP00000085244
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl143,973,167 - 44,042,131 (+)Ensembl
GRCm38.p6 Ensembl143,934,007 - 44,002,971 (+)Ensembl
Ensembl Acc Id: ENSMUST00000185579
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl143,972,807 - 43,988,565 (+)Ensembl
GRCm38.p6 Ensembl143,933,647 - 43,949,405 (+)Ensembl
Ensembl Acc Id: ENSMUST00000186028
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl143,973,175 - 43,996,161 (+)Ensembl
GRCm38.p6 Ensembl143,934,015 - 43,957,001 (+)Ensembl
Ensembl Acc Id: ENSMUST00000186441   ⟹   ENSMUSP00000139592
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl144,010,530 - 44,016,512 (+)Ensembl
GRCm38.p6 Ensembl143,971,370 - 43,977,352 (+)Ensembl
Ensembl Acc Id: ENSMUST00000187115
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl144,039,985 - 44,041,496 (+)Ensembl
GRCm38.p6 Ensembl144,000,825 - 44,002,336 (+)Ensembl
Ensembl Acc Id: ENSMUST00000188302   ⟹   ENSMUSP00000140474
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl143,973,193 - 44,029,763 (+)Ensembl
GRCm38.p6 Ensembl143,934,033 - 43,990,603 (+)Ensembl
Ensembl Acc Id: ENSMUST00000188313   ⟹   ENSMUSP00000139918
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl143,973,175 - 44,042,160 (+)Ensembl
GRCm38.p6 Ensembl143,934,015 - 44,003,000 (+)Ensembl
Ensembl Acc Id: ENSMUST00000189388   ⟹   ENSMUSP00000140562
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl143,973,205 - 44,029,744 (+)Ensembl
GRCm38.p6 Ensembl143,934,045 - 43,990,584 (+)Ensembl
Ensembl Acc Id: ENSMUST00000190207   ⟹   ENSMUSP00000140313
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl144,022,445 - 44,042,160 (+)Ensembl
GRCm38.p6 Ensembl143,983,285 - 44,003,000 (+)Ensembl
Ensembl Acc Id: ENSMUST00000190401
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl143,973,174 - 43,996,161 (+)Ensembl
GRCm38.p6 Ensembl143,934,014 - 43,957,001 (+)Ensembl
RefSeq Acc Id: NM_001310540   ⟹   NP_001297469
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39143,973,154 - 44,042,160 (+)NCBI
GRCm38143,933,994 - 44,003,000 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009418   ⟹   NP_033444
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39143,973,154 - 44,042,160 (+)NCBI
GRCm38143,933,994 - 44,003,000 (+)NCBI
MGSCv37143,990,852 - 44,059,816 (+)RGD
Celera144,277,065 - 44,346,020 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_001784011
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39143,973,130 - 44,042,160 (+)NCBI
GRCm38143,933,970 - 44,003,000 (+)NCBI
Sequence:
RefSeq Acc Id: XR_373249
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39143,973,130 - 44,042,160 (+)NCBI
GRCm38143,933,970 - 44,003,000 (+)NCBI
Sequence:
RefSeq Acc Id: NP_033444   ⟸   NM_009418
- Peptide Label: isoform 1
- UniProtKB: Q5D072 (UniProtKB/Swiss-Prot),   Q64514 (UniProtKB/Swiss-Prot),   Q3TW28 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001297469   ⟸   NM_001310540
- Peptide Label: isoform 2
- UniProtKB: Q3TW28 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000139592   ⟸   ENSMUST00000186441
Ensembl Acc Id: ENSMUSP00000085244   ⟸   ENSMUST00000087933
Ensembl Acc Id: ENSMUSP00000140313   ⟸   ENSMUST00000190207
Ensembl Acc Id: ENSMUSP00000140474   ⟸   ENSMUST00000188302
Ensembl Acc Id: ENSMUSP00000139918   ⟸   ENSMUST00000188313
Ensembl Acc Id: ENSMUSP00000140562   ⟸   ENSMUST00000189388
Protein Domains
Peptidase S8   Peptidase S8/S53   Tripeptidyl peptidase II C-terminal   Tripeptidyl peptidase II second Ig-like   Tripeptidyl-peptidase II first Ig-like   Tripeptidyl-peptidase II galactose-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64514-F1-model_v2 AlphaFold Q64514 1-1262 view protein structure

Promoters
RGD ID:6873616
Promoter ID:EPDNEW_M259
Type:initiation region
Name:Tpp2_1
Description:Mus musculus tripeptidyl peptidase II , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38143,934,051 - 43,934,111EPDNEW
RGD ID:6818636
Promoter ID:MM_KWN:601
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000087933,   ENSMUST00000097767,   UC007AVR.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36143,990,431 - 43,991,002 (+)MPROMDB
RGD ID:6818638
Promoter ID:MM_KWN:602
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour
Transcripts:UC007AVU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36144,038,799 - 44,039,299 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102724 AgrOrtholog
Ensembl Genes ENSMUSG00000041763 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000087933 ENTREZGENE
  ENSMUST00000087933.10 UniProtKB/Swiss-Prot
  ENSMUST00000188313 ENTREZGENE
  ENSMUST00000188313.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.710 UniProtKB/Swiss-Prot
  2.60.40.3170 UniProtKB/Swiss-Prot
  3.40.50.200 UniProtKB/Swiss-Prot
  6.10.250.3080 UniProtKB/Swiss-Prot
InterPro Peptidase_S8/S53_dom UniProtKB/Swiss-Prot
  Peptidase_S8/S53_dom_sf UniProtKB/Swiss-Prot
  Peptidase_S8_His-AS UniProtKB/Swiss-Prot
  Peptidase_S8_Ser-AS UniProtKB/Swiss-Prot
  Peptidase_S8_subtilisin-like UniProtKB/Swiss-Prot
  Peptidase_S8_subtilisin-rel UniProtKB/Swiss-Prot
  Peptidase_S8A_TPPII UniProtKB/Swiss-Prot
  TPP_II_domain UniProtKB/Swiss-Prot
  TPPII_C_art UniProtKB/Swiss-Prot
  TPPII_C_sf UniProtKB/Swiss-Prot
  TPPII_GBD UniProtKB/Swiss-Prot
  TPPII_Ig-like-1 UniProtKB/Swiss-Prot
  TPPII_Ig-like_sf UniProtKB/Swiss-Prot
KEGG Report mmu:22019 UniProtKB/Swiss-Prot
MGD MGI:102724 ENTREZGENE
NCBI Gene 22019 ENTREZGENE
PANTHER PEPTIDASE S8 UniProtKB/Swiss-Prot
  TRIPEPTIDYL-PEPTIDASE 2 UniProtKB/Swiss-Prot
Pfam Peptidase_S8 UniProtKB/Swiss-Prot
  TPPII UniProtKB/Swiss-Prot
  TPPII_C UniProtKB/Swiss-Prot
  TPPII_GBD UniProtKB/Swiss-Prot
  TPPII_Ig-like-1 UniProtKB/Swiss-Prot
PhenoGen Tpp2 PhenoGen
PRINTS SUBTILISIN UniProtKB/Swiss-Prot
PROSITE SUBTILASE UniProtKB/Swiss-Prot
  SUBTILASE_HIS UniProtKB/Swiss-Prot
  SUBTILASE_SER UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52743 UniProtKB/Swiss-Prot
UniProt A0A087WP19_MOUSE UniProtKB/TrEMBL
  A0A087WQR6_MOUSE UniProtKB/TrEMBL
  A0A087WRC0_MOUSE UniProtKB/TrEMBL
  Q05DJ9_MOUSE UniProtKB/TrEMBL
  Q3TB11_MOUSE UniProtKB/TrEMBL
  Q3TW28 ENTREZGENE, UniProtKB/TrEMBL
  Q3U4M7_MOUSE UniProtKB/TrEMBL
  Q5D072 ENTREZGENE
  Q64514 ENTREZGENE
  Q922K4_MOUSE UniProtKB/TrEMBL
  TPP2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q5D072 UniProtKB/Swiss-Prot