Bcl2l11 (BCL2 like 11) - Rat Genome Database

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Gene: Bcl2l11 (BCL2 like 11) Mus musculus
Analyze
Symbol: Bcl2l11
Name: BCL2 like 11
RGD ID: 734300
MGI Page MGI
Description: Enables microtubule binding activity and protein kinase binding activity. Involved in response to endoplasmic reticulum stress. Acts upstream of or within several processes, including apoptotic signaling pathway; hematopoietic or lymphoid organ development; and lymphocyte homeostasis. Located in membrane and mitochondrion. Part of Bcl-2 family protein complex. Is expressed in several structures, including hair outer root sheath; metanephros; neural tube; spleen; and trunk mesenchyme. Orthologous to human BCL2L11 (BCL2 like 11).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1500006F24Rik; bcl-2-like protein 11; Bcl2 interacting mediator of cell death; bcl2-interacting mediator of cell death; bcl2-L-11; BCL2-like 11 (apoptosis facilitator); Bi; Bim; Bo; Bod
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,967,958 - 128,004,467 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,967,958 - 128,004,467 (+)EnsemblGRCm39 Ensembl
GRCm382128,126,038 - 128,162,547 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2128,126,038 - 128,162,547 (+)EnsemblGRCm38mm10GRCm38
MGSCv372127,951,774 - 127,988,283 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362127,817,479 - 127,853,613 (+)NCBIMGSCv36mm8
Celera2129,356,352 - 129,393,704 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-amphetamine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
1H-pyrazole  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2-butoxyethanol  (EXP)
2-methoxyethanol  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-nitrophenol  (EXP)
4-nonylphenol  (ISO)
4-phenylbutyric acid  (ISO)
4-vinylcyclohexene dioxide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
7-ketocholesterol  (ISO)
8-(4-chlorophenylthio)-cAMP  (EXP,ISO)
8-Br-cAMP  (ISO)
9,10-anthraquinone  (ISO)
9-cis-retinoic acid  (ISO)
ABT-737  (EXP,ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP,ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
asbestos  (ISO)
Azaspiracid  (ISO)
azoxystrobin  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
berberine  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
Brevetoxin B  (ISO)
bufalin  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbaryl  (ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
chromium(6+)  (EXP,ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (EXP,ISO)
cobimetinib  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crizotinib  (ISO)
crocidolite asbestos  (ISO)
cucurbitacin B  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyclophosphamide  (ISO)
D-glucose  (ISO)
dactolisib  (ISO)
dantrolene  (EXP)
DDE  (ISO)
deguelin  (ISO)
dexamethasone  (EXP,ISO)
Di-n-octyl phthalate  (EXP)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
dicrotophos  (ISO)
dieldrin  (ISO)
diepoxybutane  (ISO)
diethyl malate  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
diquat  (EXP)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
efavirenz  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
enniatin  (ISO)
entinostat  (ISO)
epichlorohydrin  (ISO)
epoxiconazole  (EXP)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
ferric oxide  (EXP)
flutamide  (EXP,ISO)
fluvastatin  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (ISO)
furosemide  (ISO)
gallic acid  (EXP)
gefitinib  (ISO)
gemcitabine  (ISO)
gentamycin  (ISO)
Gingerenone A  (ISO)
glucose  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
gossypol  (ISO)
GW 6471  (EXP)
halothane  (EXP)
harmine  (ISO)
hydrogen peroxide  (EXP)
ibrutinib  (ISO)
icariin  (ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
isoflurane  (ISO)
isoprenaline  (EXP,ISO)
ketoconazole  (EXP)
lead diacetate  (EXP)
lovastatin  (ISO)
LY294002  (ISO)
maneb  (ISO)
manganese(II) chloride  (ISO)
medroxyprogesterone acetate  (ISO)
melatonin  (EXP)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
methamphetamine  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
methylseleninic acid  (ISO)
microcystin-LR  (EXP)
Mitotane  (ISO)
MK-2206  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
monodansylcadaverine  (ISO)
monosodium L-glutamate  (EXP)
morphine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nicotinamide  (ISO)
nimustine  (ISO)
NORCANTHARIDIN  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
omipalisib  (ISO)
osthole  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (EXP)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
patulin  (ISO)
PD 0325901  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
pevonedistat  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
phloretin  (EXP)
picoxystrobin  (ISO)
pinostrobin  (ISO)
pirinixic acid  (ISO)
ponatinib  (ISO)
potassium chromate  (ISO)
Pramanicin  (ISO)
proanthocyanidin  (EXP)
prochloraz  (ISO)
procyanidin B2  (EXP)
propylparaben  (ISO)
protein kinase inhibitor  (ISO)
pyrethrins  (ISO)
quercetin  (ISO)
quizartinib  (ISO)
raloxifene  (ISO)
reactive oxygen species  (ISO)
Rebamipide  (ISO)
remdesivir  (ISO)
resveratrol  (EXP,ISO)
romidepsin  (ISO)
rotenone  (ISO)
ryanodine  (EXP)
S-allylcysteine  (ISO)
sapanisertib  (ISO)
sarin  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenium atom  (ISO)
selumetinib  (ISO)
serpentine asbestos  (EXP)
silicon dioxide  (EXP,ISO)
sirolimus  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium chromate  (EXP)
sorafenib  (ISO)
streptozocin  (EXP)
succimer  (EXP,ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tanespimycin  (ISO)
taurine  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetrathiomolybdate(2-)  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
trametinib  (ISO)
Tributyltin oxide  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
triptonide  (EXP)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
valsartan  (ISO)
vemurafenib  (ISO)
vorinostat  (ISO)
withaferin A  (ISO)
xanthohumol  (ISO)
zinc atom  (ISO)
zinc protoporphyrin  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
apoptotic process  (IEA)
apoptotic process involved in embryonic digit morphogenesis  (IGI)
B cell homeostasis  (IGI,IMP)
cell-matrix adhesion  (IMP)
cellular response to amyloid-beta  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
developmental pigmentation  (IGI)
ear development  (IGI)
extrinsic apoptotic signaling pathway in absence of ligand  (IGI,IMP)
in utero embryonic development  (IGI)
intrinsic apoptotic signaling pathway in response to DNA damage  (IGI,ISO)
kidney development  (IGI)
leukocyte homeostasis  (IGI,IMP)
lymphocyte apoptotic process  (IMP)
lymphocyte homeostasis  (IGI,IMP)
male gonad development  (IGI)
mammary gland development  (IMP)
meiosis I  (IBA)
myeloid cell homeostasis  (IGI)
odontogenesis of dentin-containing tooth  (IGI)
positive regulation of apoptotic process  (IBA,IMP,ISO)
positive regulation of autophagy in response to ER overload  (ISO)
positive regulation of cell cycle  (IMP)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IMP)
positive regulation of fibroblast apoptotic process  (ISO)
positive regulation of intrinsic apoptotic signaling pathway  (ISO)
positive regulation of lymphocyte apoptotic process  (IMP)
positive regulation of mitochondrial membrane permeability involved in apoptotic process  (IGI)
positive regulation of neuron apoptotic process  (IDA)
positive regulation of protein-containing complex assembly  (ISO)
positive regulation of release of cytochrome c from mitochondria  (ISO)
positive regulation of T cell apoptotic process  (IGI,IMP)
post-embryonic development  (IGI)
regulation of apoptotic process  (IGI,ISO)
regulation of developmental pigmentation  (IGI)
regulation of organ growth  (IMP)
response to endoplasmic reticulum stress  (IDA,ISO)
spermatogenesis  (IGI)
spleen development  (IGI)
T cell apoptotic process  (IGI,IMP)
T cell homeostasis  (IGI,IMP)
thymocyte apoptotic process  (IGI)
thymus development  (IGI)
tube formation  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell differentiation  (IAGP)
abnormal B cell morphology  (IAGP)
abnormal B cell physiology  (IAGP)
abnormal B cell proliferation  (IAGP)
abnormal CD4-positive, alpha-beta T cell number  (IAGP)
abnormal CD8-positive, alpha-beta T cell physiology  (IAGP)
abnormal coat/hair pigmentation  (IAGP)
abnormal effector T cell morphology  (IAGP)
abnormal glomerular capillary morphology  (IAGP)
abnormal hair follicle melanocyte morphology  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal involution of the mammary gland  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal leukopoiesis  (IAGP)
abnormal lymph node cell ratio  (IAGP)
abnormal lymphocyte physiology  (IAGP)
abnormal mammary gland development  (IAGP)
abnormal mammary gland duct morphology  (IAGP)
abnormal NK cell morphology  (IAGP)
abnormal plasma cell morphology  (IAGP)
abnormal renal glomerulus basement membrane morphology  (IAGP)
abnormal renal glomerulus morphology  (IAGP)
abnormal response to infection  (IAGP)
abnormal seminiferous tubule epithelium morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal spleen marginal zone morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal splenic cell ratio  (IAGP)
abnormal sympathetic neuron morphology  (IAGP)
abnormal T cell differentiation  (IAGP)
abnormal T cell number  (IAGP)
abnormal T cell subpopulation ratio  (IAGP)
absent hair follicle melanin granules  (IAGP)
absent T cells  (IAGP)
arrest of male meiosis  (IAGP)
azoospermia  (IAGP)
decreased apoptosis  (IAGP)
decreased B cell apoptosis  (IAGP)
decreased B cell number  (IAGP)
decreased body weight  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased eosinophil cell number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased erythroid progenitor cell number  (IAGP)
decreased germinal center B cell number  (IAGP)
decreased immature B cell number  (IAGP)
decreased Ly6C high monocyte number  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased mature B cell number  (IAGP)
decreased mean corpuscular hemoglobin  (IEA)
decreased neutrophil cell number  (IAGP)
decreased NK T cell number  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased plasma cell number  (IAGP)
decreased pre-B cell number  (IAGP)
decreased pro-B cell number  (IAGP)
decreased spleen red pulp amount  (IAGP)
decreased splenocyte apoptosis  (IAGP)
decreased T cell apoptosis  (IAGP)
decreased testis weight  (IAGP)
decreased thymocyte apoptosis  (IAGP)
decreased total body fat amount  (IEA)
dilated renal tubule  (IAGP)
diluted coat color  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
expanded mesangial matrix  (IAGP)
gliosis  (IAGP)
glomerular crescent  (IAGP)
glomerulonephritis  (IAGP)
hydrometrocolpos  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased anti-histone antibody level  (IAGP)
increased anti-nuclear antigen antibody level  (IAGP)
increased anti-single stranded DNA antibody level  (IAGP)
increased autoantibody level  (IAGP)
increased B cell derived lymphoma incidence  (IAGP)
increased B cell number  (IAGP)
increased B-2 B cell number  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased CD4-positive, alpha-beta T cell number  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased circulating potassium level  (IEA)
increased dendritic cell number  (IAGP)
increased double-negative T cell number  (IAGP)
increased erythrocyte cell number  (IEA)
increased fibroblast apoptosis  (IAGP)
increased follicular B cell number  (IAGP)
increased germinal center B cell number  (IAGP)
increased granulocyte number  (IAGP)
increased grip strength  (IEA)
increased IgA level  (IAGP)
increased IgG level  (IAGP)
increased IgM level  (IAGP)
increased immature B cell number  (IAGP)
increased immunoglobulin level  (IAGP)
increased inflammatory response  (IAGP)
increased kidney cell proliferation  (IAGP)
increased large unstained cell number  (IEA)
increased leukocyte cell number  (IAGP)
increased lymphocyte cell number  (IEA)
increased lymphoma incidence  (IAGP)
increased macrophage cell number  (IAGP)
increased marginal zone B cell number  (IAGP)
increased mature B cell number  (IAGP)
increased memory T cell number  (IAGP)
increased monocyte cell number  (IAGP)
increased NK cell number  (IAGP)
increased pre-B cell number  (IAGP)
increased regulatory T cell number  (IAGP)
increased renal glomerulus apoptosis  (IAGP)
increased renal glomerulus basement membrane thickness  (IAGP)
increased spleen weight  (IAGP)
increased spleen white pulp amount  (IAGP)
increased splenocyte number  (IAGP)
increased susceptibility to autoimmune disorder  (IAGP)
increased T cell apoptosis  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased T cell number  (IAGP)
increased thymocyte number  (IAGP)
increased transitional stage B cell number  (IAGP)
interdigital webbing  (IAGP)
lymph node hyperplasia  (IAGP)
male infertility  (IAGP)
multinucleated giant male germ cells  (IAGP)
no abnormal phenotype detected  (IAGP)
polycystic kidney  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
renal cast  (IAGP)
renal glomerular immunoglobulin deposits  (IAGP)
renal glomerulus hypertrophy  (IAGP)
small seminiferous tubules  (IAGP)
spleen hyperplasia  (IAGP)
thrombocytopenia  (IAGP)
vagina atresia  (IAGP)
vascular inflammation  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Bouillet P, etal., Science 1999 Nov 26;286(5445):1735-8.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. BH3-only proteins in apoptosis and beyond: an overview. Lomonosova E and Chinnadurai G, Oncogene. 2008 Dec;27 Suppl 1:S2-19.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. Comparative analysis of apoptosis and inflammation genes of mice and humans. Reed JC, etal., Genome Res 2003 Jun;13(6B):1376-88.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9430630   PMID:9916985   PMID:10198631   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11210187   PMID:11301022   PMID:11546872   PMID:11709185   PMID:11804782   PMID:11859372  
PMID:11980919   PMID:12121658   PMID:12142566   PMID:12374983   PMID:12433687   PMID:12477932   PMID:12520002   PMID:12637528   PMID:12717433   PMID:12749905   PMID:12818176   PMID:14499110  
PMID:14517273   PMID:14561217   PMID:14610273   PMID:14623954   PMID:14635229   PMID:14657036   PMID:14668867   PMID:14713957   PMID:14962910   PMID:14996839   PMID:15079075   PMID:15118096  
PMID:15136728   PMID:15210829   PMID:15226421   PMID:15231831   PMID:15292207   PMID:15486085   PMID:15489334   PMID:15504823   PMID:15520248   PMID:15589170   PMID:15592435   PMID:15634885  
PMID:15694340   PMID:15766661   PMID:15782199   PMID:15818405   PMID:15843898   PMID:15967824   PMID:16034091   PMID:16055554   PMID:16116198   PMID:16118324   PMID:16141072   PMID:16141073  
PMID:16227588   PMID:16260615   PMID:16270031   PMID:16282323   PMID:16282979   PMID:16301744   PMID:16373335   PMID:16455986   PMID:16520387   PMID:16543145   PMID:16585545   PMID:16602821  
PMID:16645638   PMID:16651384   PMID:16673448   PMID:16705087   PMID:16738314   PMID:16761315   PMID:16780816   PMID:16782750   PMID:16832056   PMID:16909112   PMID:16912311   PMID:16930425  
PMID:16955144   PMID:17007835   PMID:17009248   PMID:17074758   PMID:17095659   PMID:17101770   PMID:17116875   PMID:17167080   PMID:17177603   PMID:17178918   PMID:17227827   PMID:17276340  
PMID:17283183   PMID:17289999   PMID:17307841   PMID:17312102   PMID:17322888   PMID:17442051   PMID:17470784   PMID:17476283   PMID:17482686   PMID:17483459   PMID:17510659   PMID:17517961  
PMID:17535852   PMID:17559169   PMID:17579027   PMID:17585338   PMID:17591857   PMID:17592965   PMID:17604722   PMID:17618288   PMID:17634411   PMID:17705137   PMID:17709751   PMID:17720882  
PMID:17785775   PMID:17869640   PMID:17884340   PMID:17913922   PMID:17953376   PMID:17955375   PMID:17982458   PMID:18006817   PMID:18032672   PMID:18046413   PMID:18048346   PMID:18086806  
PMID:18198176   PMID:18251703   PMID:18272391   PMID:18275830   PMID:18275831   PMID:18275832   PMID:18281283   PMID:18287039   PMID:18288109   PMID:18292495   PMID:18299399   PMID:18327259  
PMID:18329371   PMID:18390708   PMID:18419764   PMID:18420585   PMID:18454133   PMID:18498746   PMID:18566606   PMID:18589438   PMID:18606610   PMID:18619445   PMID:18691453   PMID:18691924  
PMID:18715233   PMID:18715501   PMID:18805964   PMID:18806761   PMID:18971628   PMID:18981230   PMID:19017949   PMID:19017950   PMID:19033888   PMID:19064725   PMID:19064728   PMID:19079139  
PMID:19088189   PMID:19100522   PMID:19100675   PMID:19104441   PMID:19109422   PMID:19119023   PMID:19135479   PMID:19150432   PMID:19228953   PMID:19234182   PMID:19285955   PMID:19293378  
PMID:19339988   PMID:19342627   PMID:19407828   PMID:19411758   PMID:19454543   PMID:19542438   PMID:19641036   PMID:19651893   PMID:19779495   PMID:19805519   PMID:19815516   PMID:19841067  
PMID:19846553   PMID:19853566   PMID:19917256   PMID:19933849   PMID:19933852   PMID:19949106   PMID:19950021   PMID:19959756   PMID:19965635   PMID:20028660   PMID:20057504   PMID:20072628  
PMID:20103739   PMID:20127674   PMID:20190135   PMID:20300112   PMID:20351066   PMID:20371704   PMID:20400700   PMID:20431598   PMID:20471291   PMID:20497470   PMID:20523353   PMID:20570860  
PMID:20631380   PMID:20656893   PMID:20664053   PMID:20708584   PMID:20711984   PMID:20829369   PMID:20831893   PMID:20844198   PMID:20872776   PMID:20921405   PMID:20921992   PMID:21047504  
PMID:21061436   PMID:21083429   PMID:21098226   PMID:21127253   PMID:21146511   PMID:21148799   PMID:21151042   PMID:21151127   PMID:21159964   PMID:21198986   PMID:21221781   PMID:21267068  
PMID:21339291   PMID:21339359   PMID:21364616   PMID:21367852   PMID:21378313   PMID:21378976   PMID:21389258   PMID:21403399   PMID:21423172   PMID:21451108   PMID:21475200   PMID:21478148  
PMID:21518881   PMID:21533046   PMID:21546576   PMID:21642990   PMID:21646395   PMID:21654829   PMID:21660046   PMID:21727192   PMID:21734077   PMID:21738214   PMID:21742968   PMID:21762490  
PMID:21788582   PMID:21820438   PMID:21839428   PMID:21858169   PMID:21873635   PMID:21928281   PMID:21937453   PMID:21949016   PMID:21977009   PMID:22006951   PMID:22015606   PMID:22036586  
PMID:22043021   PMID:22081075   PMID:22084408   PMID:22086418   PMID:22117046   PMID:22117047   PMID:22156338   PMID:22169007   PMID:22201126   PMID:22215602   PMID:22240894   PMID:22257939  
PMID:22289787   PMID:22301689   PMID:22322859   PMID:22345564   PMID:22425249   PMID:22427990   PMID:22446994   PMID:22510886   PMID:22523592   PMID:22538851   PMID:22539004   PMID:22632729  
PMID:22728771   PMID:22742832   PMID:22760702   PMID:22761832   PMID:22833783   PMID:22891272   PMID:22905229   PMID:22949644   PMID:22960223   PMID:22996683   PMID:23000175   PMID:23180554  
PMID:23278598   PMID:23325888   PMID:23337809   PMID:23453633   PMID:23532334   PMID:23558951   PMID:23569244   PMID:23577147   PMID:23623381   PMID:23644507   PMID:23666531   PMID:23668821  
PMID:23717580   PMID:23805138   PMID:23840678   PMID:23840878   PMID:23852275   PMID:23852375   PMID:23858035   PMID:23869083   PMID:23872792   PMID:23881917   PMID:23918371   PMID:23974197  
PMID:23982205   PMID:23986435   PMID:24056747   PMID:24060902   PMID:24352880   PMID:24407239   PMID:24500693   PMID:24534189   PMID:24625983   PMID:24632712   PMID:24658302   PMID:24658772  
PMID:24663676   PMID:24700126   PMID:24760140   PMID:24785297   PMID:24825007   PMID:24835393   PMID:24858047   PMID:24908390   PMID:24952961   PMID:24958849   PMID:24966929   PMID:24971484  
PMID:24986687   PMID:25012505   PMID:25032866   PMID:25081090   PMID:25124553   PMID:25176652   PMID:25184675   PMID:25187648   PMID:25263124   PMID:25263453   PMID:25299771   PMID:25301392  
PMID:25375379   PMID:25430770   PMID:25483735   PMID:25486906   PMID:25551609   PMID:25565426   PMID:25605735   PMID:25687757   PMID:25698446   PMID:25732191   PMID:25908663   PMID:25919951  
PMID:25948683   PMID:25976060   PMID:26045049   PMID:26109645   PMID:26121028   PMID:26197709   PMID:26254608   PMID:26269257   PMID:26344567   PMID:26378075   PMID:26383973   PMID:26404745  
PMID:26438731   PMID:26438836   PMID:26441343   PMID:26497683   PMID:26563351   PMID:26660116   PMID:26785352   PMID:26795246   PMID:26832406   PMID:26856538   PMID:26901150   PMID:26943318  
PMID:26947081   PMID:27001308   PMID:27013495   PMID:27043411   PMID:27044867   PMID:27055867   PMID:27060196   PMID:27064265   PMID:27095570   PMID:27130031   PMID:27195679   PMID:27302161  
PMID:27371614   PMID:27525555   PMID:27601261   PMID:27621418   PMID:27797453   PMID:27820810   PMID:27843137   PMID:27852740   PMID:27869196   PMID:27888447   PMID:27894079   PMID:28007900  
PMID:28031476   PMID:28294596   PMID:28362433   PMID:28378742   PMID:28394372   PMID:28409774   PMID:28427239   PMID:28446592   PMID:28530714   PMID:28552963   PMID:28553951   PMID:28652304  
PMID:28682312   PMID:28847007   PMID:28864471   PMID:28885618   PMID:28922373   PMID:28928277   PMID:28947542   PMID:29038463   PMID:29053141   PMID:29114065   PMID:29141222   PMID:29149594  
PMID:29411880   PMID:29623080   PMID:30154103   PMID:30232009   PMID:30301924   PMID:30590105   PMID:30607541   PMID:30610162   PMID:30655546   PMID:30858352   PMID:30860395   PMID:30894677  
PMID:30970248   PMID:31079418   PMID:31189926   PMID:31260649   PMID:31296963   PMID:31334597   PMID:31558776   PMID:31591473   PMID:31699777   PMID:31813995   PMID:31949051   PMID:31976859  
PMID:31978211   PMID:31993851   PMID:32082327   PMID:32365083   PMID:32579941   PMID:32657438   PMID:32832688   PMID:32868930   PMID:32889526   PMID:32963096   PMID:33086063   PMID:33086067  
PMID:33087587   PMID:33147210   PMID:33184218   PMID:33203937   PMID:33236795   PMID:33253203   PMID:33293517   PMID:33323382   PMID:34247195   PMID:35149957   PMID:36145242   PMID:36206490  
PMID:36754276   PMID:36755068   PMID:37702066   PMID:37772397   PMID:38039134   PMID:38113886   PMID:38355793  


Genomics

Comparative Map Data
Bcl2l11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,967,958 - 128,004,467 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,967,958 - 128,004,467 (+)EnsemblGRCm39 Ensembl
GRCm382128,126,038 - 128,162,547 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2128,126,038 - 128,162,547 (+)EnsemblGRCm38mm10GRCm38
MGSCv372127,951,774 - 127,988,283 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362127,817,479 - 127,853,613 (+)NCBIMGSCv36mm8
Celera2129,356,352 - 129,393,704 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.23NCBI
BCL2L11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382111,120,914 - 111,168,445 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2111,119,378 - 111,168,444 (+)EnsemblGRCh38hg38GRCh38
GRCh372111,878,491 - 111,926,022 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362111,594,962 - 111,642,493 (+)NCBINCBI36Build 36hg18NCBI36
Build 342111,597,540 - 111,640,814NCBI
Celera2105,529,086 - 105,576,607 (+)NCBICelera
Cytogenetic Map2q13NCBI
HuRef2104,757,646 - 104,805,166 (+)NCBIHuRef
CHM1_12111,882,732 - 111,930,286 (+)NCBICHM1_1
T2T-CHM13v2.02111,543,978 - 111,591,507 (+)NCBIT2T-CHM13v2.0
Bcl2l11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83135,820,042 - 135,857,330 (+)NCBIGRCr8
mRatBN7.23115,366,783 - 115,404,068 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3115,366,646 - 115,404,068 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3119,256,253 - 119,293,586 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03127,851,801 - 127,889,132 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03125,512,142 - 125,549,477 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03120,726,906 - 120,764,192 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3120,726,906 - 120,764,192 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03126,567,484 - 126,604,461 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43115,692,323 - 115,722,701 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13115,597,895 - 115,628,274 (+)NCBI
Celera3114,200,283 - 114,237,903 (+)NCBICelera
Cytogenetic Map3q36NCBI
Bcl2l11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554702,740,682 - 2,780,225 (-)NCBIChiLan1.0ChiLan1.0
BCL2L11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21216,914,260 - 16,961,753 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A16,917,024 - 16,964,367 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A90,862,070 - 90,909,833 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A112,337,927 - 112,385,079 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A112,337,927 - 112,385,079 (+)Ensemblpanpan1.1panPan2
BCL2L11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11735,619,804 - 35,665,782 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1735,619,582 - 35,664,587 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1735,391,228 - 35,441,388 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01736,397,661 - 36,447,779 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1736,397,342 - 36,445,321 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11735,515,071 - 35,565,168 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01735,589,049 - 35,639,236 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01735,800,089 - 35,850,247 (+)NCBIUU_Cfam_GSD_1.0
Bcl2l11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629281,122,091 - 81,156,497 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493678318,194 - 50,983 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493678315,493 - 50,959 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCL2L11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl345,160,155 - 45,201,186 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1345,156,791 - 45,202,996 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2347,180,506 - 47,223,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BCL2L11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11414,178,159 - 14,205,337 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660805,463,438 - 5,508,960 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcl2l11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247491,091,096 - 1,125,341 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247491,033,824 - 1,130,099 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bcl2l11
1009 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4896
Count of miRNA genes:899
Interacting mature miRNAs:1274
Transcripts:ENSMUST00000019281, ENSMUST00000089634, ENSMUST00000103210, ENSMUST00000103211, ENSMUST00000110341, ENSMUST00000129206, ENSMUST00000132201, ENSMUST00000146023
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
13506763Tbvq1_mtrabecular bone volume QTL 1 (mouse)2126041920135441920Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
1300798Actre3_mactivity response to ethanol 3 (mouse)Not determined2112024987128173821Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1301415Actre4_mactivity response to ethanol 4 (mouse)Not determined2112024987128173821Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1301066Otx2m2_morthodenticle homolog 2 (Drosophila) modifier 2 (mouse)Not determined2123231973148700377Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1300712El2_mepilepsy 2 (mouse)Not determined2122207146142532135Mouse

Markers in Region
RH131553  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382128,162,197 - 128,162,398UniSTSGRCm38
MGSCv372127,987,933 - 127,988,134UniSTSGRCm37
Celera2129,393,354 - 129,393,555UniSTS
Cytogenetic Map2F3-G1UniSTS
BB257531  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382128,160,854 - 128,160,936UniSTSGRCm38
MGSCv372127,986,590 - 127,986,672UniSTSGRCm37
Celera2129,392,011 - 129,392,093UniSTS
Cytogenetic Map2F3-G1UniSTS
Whitehead/MRC_RH21592.55UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001284410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001406057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001406058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001406059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001406060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001406061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_207680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_207681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA275665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AA881651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF032459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF032460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF032461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF302804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK031285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK037885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK177547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL805950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC019556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE136124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA321725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB521709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000019281   ⟹   ENSMUSP00000019281
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,967,958 - 128,002,881 (+)Ensembl
GRCm38.p6 Ensembl2128,126,038 - 128,160,961 (+)Ensembl
Ensembl Acc Id: ENSMUST00000089634   ⟹   ENSMUSP00000087062
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,967,958 - 127,973,415 (+)Ensembl
GRCm38.p6 Ensembl2128,126,038 - 128,131,495 (+)Ensembl
Ensembl Acc Id: ENSMUST00000103210   ⟹   ENSMUSP00000099499
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,967,970 - 128,003,148 (+)Ensembl
GRCm38.p6 Ensembl2128,126,050 - 128,161,228 (+)Ensembl
Ensembl Acc Id: ENSMUST00000103211   ⟹   ENSMUSP00000099500
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,967,960 - 128,000,362 (+)Ensembl
GRCm38.p6 Ensembl2128,126,040 - 128,158,442 (+)Ensembl
Ensembl Acc Id: ENSMUST00000110341   ⟹   ENSMUSP00000105970
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,967,959 - 128,004,467 (+)Ensembl
GRCm38.p6 Ensembl2128,126,039 - 128,162,547 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129206
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,969,495 - 127,972,065 (+)Ensembl
GRCm38.p6 Ensembl2128,127,575 - 128,130,145 (+)Ensembl
Ensembl Acc Id: ENSMUST00000132201
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,970,051 - 127,970,657 (+)Ensembl
GRCm38.p6 Ensembl2128,128,131 - 128,128,737 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146023
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,967,958 - 127,971,935 (+)Ensembl
GRCm38.p6 Ensembl2128,126,038 - 128,130,015 (+)Ensembl
RefSeq Acc Id: NM_001284410   ⟹   NP_001271339
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,969,526 - 127,973,418 (+)NCBI
GRCm382128,127,575 - 128,131,498 (+)NCBI
Celera2129,356,352 - 129,393,704 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291016   ⟹   NP_001277945
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,967,958 - 127,973,418 (+)NCBI
GRCm382128,126,038 - 128,131,498 (+)NCBI
Celera2129,356,352 - 129,393,704 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001406057   ⟹   NP_001392986
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,969,526 - 128,004,467 (+)NCBI
RefSeq Acc Id: NM_001406058   ⟹   NP_001392987
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,969,526 - 128,004,467 (+)NCBI
RefSeq Acc Id: NM_001406059   ⟹   NP_001392988
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,967,958 - 127,991,140 (+)NCBI
RefSeq Acc Id: NM_001406060   ⟹   NP_001392989
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,969,526 - 127,991,140 (+)NCBI
RefSeq Acc Id: NM_001406061   ⟹   NP_001392990
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,967,958 - 128,004,467 (+)NCBI
RefSeq Acc Id: NM_009754   ⟹   NP_033884
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,967,958 - 128,004,467 (+)NCBI
GRCm382128,126,038 - 128,162,547 (+)NCBI
MGSCv372127,951,774 - 127,988,283 (+)RGD
Celera2129,356,352 - 129,393,704 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_207680   ⟹   NP_997563
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,967,958 - 128,004,467 (+)NCBI
GRCm382128,126,038 - 128,162,547 (+)NCBI
MGSCv372127,951,774 - 127,988,283 (+)RGD
Celera2129,356,352 - 129,393,704 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_207681   ⟹   NP_997564
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,967,958 - 128,004,467 (+)NCBI
GRCm382128,126,038 - 128,162,547 (+)NCBI
MGSCv372127,951,774 - 127,988,283 (+)RGD
Celera2129,356,352 - 129,393,704 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006498614   ⟹   XP_006498677
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,969,459 - 128,004,467 (+)NCBI
GRCm382128,127,543 - 128,162,547 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006498615   ⟹   XP_006498678
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,969,459 - 127,976,198 (+)NCBI
GRCm382128,127,543 - 128,135,541 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001271339 (Get FASTA)   NCBI Sequence Viewer  
  NP_001277945 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392986 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392987 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392988 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392989 (Get FASTA)   NCBI Sequence Viewer  
  NP_001392990 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420399 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420400 (Get FASTA)   NCBI Sequence Viewer  
  NP_001420401 (Get FASTA)   NCBI Sequence Viewer  
  NP_033884 (Get FASTA)   NCBI Sequence Viewer  
  NP_997563 (Get FASTA)   NCBI Sequence Viewer  
  NP_997564 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498677 (Get FASTA)   NCBI Sequence Viewer  
  XP_006498678 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC40029 (Get FASTA)   NCBI Sequence Viewer  
  AAC40030 (Get FASTA)   NCBI Sequence Viewer  
  AAC40031 (Get FASTA)   NCBI Sequence Viewer  
  AAH19556 (Get FASTA)   NCBI Sequence Viewer  
  AAH58175 (Get FASTA)   NCBI Sequence Viewer  
  BAC38548 (Get FASTA)   NCBI Sequence Viewer  
  BAE29581 (Get FASTA)   NCBI Sequence Viewer  
  BAE31246 (Get FASTA)   NCBI Sequence Viewer  
  BAE32079 (Get FASTA)   NCBI Sequence Viewer  
  BAE37144 (Get FASTA)   NCBI Sequence Viewer  
  EDL28212 (Get FASTA)   NCBI Sequence Viewer  
  EDL28213 (Get FASTA)   NCBI Sequence Viewer  
  EDL28214 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000087062
  ENSMUSP00000087062.6
  ENSMUSP00000099499
  ENSMUSP00000099499.2
  ENSMUSP00000099500
  ENSMUSP00000099500.2
  ENSMUSP00000105970
  ENSMUSP00000105970.3
GenBank Protein O54918 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_997563   ⟸   NM_207680
- Peptide Label: isoform 1
- UniProtKB: O54919 (UniProtKB/Swiss-Prot),   A2ALQ6 (UniProtKB/Swiss-Prot),   O54920 (UniProtKB/Swiss-Prot),   O54918 (UniProtKB/Swiss-Prot),   Q542N5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_997564   ⟸   NM_207681
- Peptide Label: isoform 2
- UniProtKB: O54918 (UniProtKB/Swiss-Prot),   Q542N5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_033884   ⟸   NM_009754
- Peptide Label: isoform 3
- UniProtKB: Q3U7X3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001271339   ⟸   NM_001284410
- Peptide Label: isoform 4
- UniProtKB: Q6PEB3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498677   ⟸   XM_006498614
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006498678   ⟸   XM_006498615
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: NP_001277945   ⟸   NM_001291016
- Peptide Label: isoform 4
- UniProtKB: Q6PEB3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000105970   ⟸   ENSMUST00000110341
Ensembl Acc Id: ENSMUSP00000087062   ⟸   ENSMUST00000089634
Ensembl Acc Id: ENSMUSP00000019281   ⟸   ENSMUST00000019281
Ensembl Acc Id: ENSMUSP00000099500   ⟸   ENSMUST00000103211
Ensembl Acc Id: ENSMUSP00000099499   ⟸   ENSMUST00000103210
RefSeq Acc Id: NP_001392990   ⟸   NM_001406061
- Peptide Label: isoform 7
RefSeq Acc Id: NP_001392988   ⟸   NM_001406059
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001392986   ⟸   NM_001406057
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001392987   ⟸   NM_001406058
- Peptide Label: isoform 3
- UniProtKB: Q3U7X3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001392989   ⟸   NM_001406060
- Peptide Label: isoform 6
Protein Domains
Apoptosis Bim N-terminal   Bcl-x interacting BH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54918-F1-model_v2 AlphaFold O54918 1-196 view protein structure

Promoters
RGD ID:6830894
Promoter ID:MM_KWN:31632
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000019281,   NM_009754,   NM_207680,   NM_207681,   OTTMUST00000036399,   OTTMUST00000036400,   UC008MGJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362127,951,579 - 127,952,079 (+)MPROMDB
RGD ID:6830896
Promoter ID:MM_KWN:31633
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000050696,   OTTMUST00000036404,   UC008MGN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362127,952,446 - 127,953,717 (+)MPROMDB
RGD ID:6878676
Promoter ID:EPDNEW_M2789
Type:multiple initiation site
Name:Bcl2l11_1
Description:Mus musculus BCL2-like 11 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2790  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382128,126,038 - 128,126,098EPDNEW
RGD ID:6878678
Promoter ID:EPDNEW_M2790
Type:initiation region
Name:Bcl2l11_2
Description:Mus musculus BCL2-like 11 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2789  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382128,128,131 - 128,128,191EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1197519 AgrOrtholog
Ensembl Genes ENSMUSG00000027381 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000089634 ENTREZGENE
  ENSMUST00000089634.12 UniProtKB/TrEMBL
  ENSMUST00000103210 ENTREZGENE
  ENSMUST00000103210.2 UniProtKB/Swiss-Prot
  ENSMUST00000103211 ENTREZGENE
  ENSMUST00000103211.8 UniProtKB/Swiss-Prot
  ENSMUST00000110341 ENTREZGENE
  ENSMUST00000110341.9 UniProtKB/Swiss-Prot
InterPro Apoptosis_Bim_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl-2-like_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bcl-x_interacting_BH3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immune_Signaling-Apoptosis_Reg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12125 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1197519 ENTREZGENE
NCBI Gene 12125 ENTREZGENE
PANTHER BCL-2-LIKE PROTEIN 11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BCL2 INTERACTING MEDIATOR OF CELL DEATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Bclx_interact UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Bim_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bcl2l11 PhenoGen
PIRSF Bcl-2-like_p11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2ALQ6 ENTREZGENE
  B2L11_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  O54919 ENTREZGENE
  O54920 ENTREZGENE
  Q3TR86_MOUSE UniProtKB/TrEMBL
  Q3U7X3 ENTREZGENE, UniProtKB/TrEMBL
  Q542N5 ENTREZGENE, UniProtKB/TrEMBL
  Q6PEB3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A2ALQ6 UniProtKB/Swiss-Prot
  O54919 UniProtKB/Swiss-Prot
  O54920 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Bcl2l11  BCL2 like 11  Bcl2l11  BCL2-like 11 (apoptosis facilitator)  Symbol and/or name change 5135510 APPROVED