Mybph (myosin binding protein H) - Rat Genome Database

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Gene: Mybph (myosin binding protein H) Mus musculus
Analyze
Symbol: Mybph
Name: myosin binding protein H
RGD ID: 734273
MGI Page MGI
Description: Predicted to act upstream of or within cell adhesion. Predicted to be located in myosin filament. Is expressed in diaphragm; limb; skeletal musculature; and tail mesenchyme. Orthologous to human MYBPH (myosin binding protein H); INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI385643; H-protein; MGC144854; MGC144855; MyBP-H; myosin-binding protein H
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,121,159 - 134,128,975 (+)NCBIGRCm39mm39
GRCm39 Ensembl1134,121,186 - 134,128,970 (+)Ensembl
GRCm381134,193,418 - 134,201,237 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,193,448 - 134,201,232 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,090,025 - 136,097,809 (+)NCBIGRCm37mm9NCBIm37
MGSCv361136,009,859 - 136,017,643 (+)NCBImm8
Celera1136,805,964 - 136,813,747 (+)NCBICelera
Cytogenetic Map1E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16638982   PMID:21267068   PMID:21677750   PMID:22673621   PMID:27166947  
PMID:27743478   PMID:28378742  


Genomics

Comparative Map Data
Mybph
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,121,159 - 134,128,975 (+)NCBIGRCm39mm39
GRCm39 Ensembl1134,121,186 - 134,128,970 (+)Ensembl
GRCm381134,193,418 - 134,201,237 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,193,448 - 134,201,232 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,090,025 - 136,097,809 (+)NCBIGRCm37mm9NCBIm37
MGSCv361136,009,859 - 136,017,643 (+)NCBImm8
Celera1136,805,964 - 136,813,747 (+)NCBICelera
Cytogenetic Map1E4NCBI
MYBPH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1203,167,811 - 203,175,826 (-)EnsemblGRCh38hg38GRCh38
GRCh381203,167,811 - 203,175,826 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371203,136,939 - 203,144,954 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,403,562 - 201,411,565 (-)NCBINCBI36hg18NCBI36
Build 341199,868,595 - 199,876,599NCBI
Celera1176,266,180 - 176,274,183 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,302,068 - 174,310,071 (-)NCBIHuRef
CHM1_11204,559,258 - 204,567,263 (-)NCBICHM1_1
Mybph
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21345,653,156 - 45,660,893 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1345,653,234 - 45,660,893 (+)Ensembl
Rnor_6.01351,034,228 - 51,041,903 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,034,256 - 51,041,902 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01356,089,915 - 56,097,580 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,151,091 - 47,158,665 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11347,165,133 - 47,172,708 (+)NCBI
Celera1345,981,355 - 45,988,929 (+)NCBICelera
Cytogenetic Map13q13NCBI
Mybph
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540639,184,691 - 39,191,741 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540639,174,864 - 39,191,969 (-)NCBIChiLan1.0ChiLan1.0
MYBPH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11183,065,188 - 183,072,188 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1183,065,021 - 183,072,188 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01178,769,183 - 178,777,737 (-)NCBIMhudiblu_PPA_v0panPan3
MYBPH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1734,181 - 44,479 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl736,428 - 43,803 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha791,094 - 100,208 (+)NCBI
ROS_Cfam_1.0745,844 - 54,962 (+)NCBI
UMICH_Zoey_3.1734,076 - 43,199 (+)NCBI
UNSW_CanFamBas_1.07143,675 - 152,776 (+)NCBI
UU_Cfam_GSD_1.07166,080 - 175,211 (+)NCBI
Mybph
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,187,287 - 72,195,094 (+)NCBI
SpeTri2.0NW_0049365671,421,965 - 1,429,771 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYBPH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9113,873,471 - 113,895,024 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19113,872,439 - 113,884,544 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29125,331,945 - 125,341,102 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYBPH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,172,236 - 26,180,502 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2526,172,495 - 26,179,656 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605526,948,542 - 26,956,927 (+)NCBIVero_WHO_p1.0
Mybph
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248077,665,505 - 7,673,819 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
AI385643  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381134,200,948 - 134,201,070UniSTSGRCm38
MGSCv371136,097,525 - 136,097,647UniSTSGRCm37
Celera1136,813,463 - 136,813,585UniSTS
Cytogenetic Map1E4UniSTS
Whitehead/MRC_RH11773.74UniSTS
AI848715  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381134,199,417 - 134,199,496UniSTSGRCm38
MGSCv371136,095,994 - 136,096,073UniSTSGRCm37
Celera1136,811,932 - 136,812,011UniSTS
Cytogenetic Map1E4UniSTS
Whitehead/MRC_RH11773.19UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13824984Twq5_mtestis weight QTL 5 (mouse)13000000185000000Mouse
1357753Kidq2_mkidney weight QTL 2 (mouse)Not determined134721057150318120Mouse
1357488Splq3_mspleen weight QTL 3 (mouse)Not determined134721057150318120Mouse
1558860W10q7_mweight 10 weeks QTL 7 (mouse)Not determined134721057150318120Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145744740189571420Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52418578182423027Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163815531189571420Mouse
1300841Ssial1_msusceptibility to sialadenitis 1 (mouse)Not determined163880843153681816Mouse
1300989Lrdg1_mlight induced retinal degeneration 1 (mouse)Not determined173716016147249632Mouse
4141914Gcsfis_mG-CSF induced splenomegaly (mouse)Not determined74477076148839837Mouse
27095928Pglq6_mpelvic girdle length QTL 6, 10 week (mouse)176000000148900000Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)176000000181500000Mouse
1301350Nidd4k_mNidd4 on KK-A (mouse)Not determined782314261147249632Mouse
1357439Popoa_mpremature ovulation and primary oocyte arrest (mouse)Not determined182665468135687641Mouse
27095913Scvln2_msacral vertebrae length 2, 5 week (mouse)194200000148900000Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194200000172200000Mouse
27226779Tibl1_mtibia length 1, 5 week (mouse)195600000162200000Mouse
1301193Lxw3_mlupus BXSB x NZW 3 (mouse)Not determined1103040804137040937Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1104005680191493284Mouse
12790994Aaaq1_maortic arch angle QTL 1 (mouse)1109568206143568206Mouse
1301979Melm1_mmelanoma modifier 1 (mouse)Not determined1109710525143710742Mouse
1357600Obq17_mobesity QTL 17 (mouse)Not determined1110625442144625561Mouse
10401248Bglu12_mblood glucose level 12 (mouse)Not determined1110625442144625561Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112081092168358833Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112081092175641372Mouse
1301249Sbw1_msplenomegaly-NZB x NZW 1 (mouse)Not determined1112203268146203348Mouse
10045640Jckm4_mjuvenile cystic kidney modifier 4 (mouse)Not determined1116363098150363199Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117600000180000000Mouse
1302161Exq2_mexploratory and excitability QTL 2 (mouse)Not determined1118171982152172078Mouse
27226714Metcl1_mmetatarsal-calcaneal length 1, 5 week (mouse)1121800000139800000Mouse
27226740Metcl13_mmetatarsal-calcaneal length 13, 16 week (mouse)1121800000153900000Mouse
27226743Metcl7_mmetatarsal-calcaneal length 7, 10 week (mouse)1121800000154000000Mouse
27226767Tibl10_mtibia length 10, 10 week (mouse)1121800000165000000Mouse
27226799Feml5_mfemur length 5, 5 week (mouse)1122100000165000000Mouse
12880408V125Dq3_mvitamin D active form serum level QTL 3 (mouse)1123000000157000000Mouse
1301488Tir3b_mtrypansomiasis infection response 3b (mouse)Not determined1128551097157361794Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128800000181500000Mouse
1301608Emo3_memotionality 3 (mouse)Not determined1129255120163255255Mouse
1302128Ity3_mimmunity to S. typhimurium 3 (mouse)Not determined11131228571165311895Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:161
Count of miRNA genes:138
Interacting mature miRNAs:146
Transcripts:ENSMUST00000038445
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000038445   ⟹   ENSMUSP00000042195
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1134,121,186 - 134,128,969 (+)Ensembl
GRCm38.p6 Ensembl1134,193,448 - 134,201,231 (+)Ensembl
RefSeq Acc Id: ENSMUST00000191577   ⟹   ENSMUSP00000141104
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1134,121,195 - 134,128,970 (+)Ensembl
GRCm38.p6 Ensembl1134,193,457 - 134,201,232 (+)Ensembl
RefSeq Acc Id: NM_001357515   ⟹   NP_001344444
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,121,186 - 134,128,975 (+)NCBI
GRCm381134,193,448 - 134,201,237 (+)NCBI
Sequence:
RefSeq Acc Id: NM_016749   ⟹   NP_058029
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,121,186 - 134,128,970 (+)NCBI
GRCm381134,193,448 - 134,201,232 (+)NCBI
MGSCv371136,090,025 - 136,097,809 (+)RGD
Celera1136,805,964 - 136,813,747 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006529753   ⟹   XP_006529816
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,121,159 - 134,128,972 (+)NCBI
GRCm381134,193,418 - 134,201,237 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003956240
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,121,159 - 134,128,972 (+)NCBI
GRCm381134,193,418 - 134,201,237 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003956241
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391134,121,159 - 134,128,972 (+)NCBI
GRCm381134,193,418 - 134,201,237 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_058029   ⟸   NM_016749
- UniProtKB: P70402 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006529816   ⟸   XM_006529753
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001344444   ⟸   NM_001357515
RefSeq Acc Id: ENSMUSP00000141104   ⟸   ENSMUST00000191577
RefSeq Acc Id: ENSMUSP00000042195   ⟸   ENSMUST00000038445
Promoters
RGD ID:6874994
Promoter ID:EPDNEW_M948
Type:single initiation site
Name:Mybph_1
Description:Mus musculus myosin binding protein H , transcript variant 1,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381134,193,439 - 134,193,499EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1858196 AgrOrtholog
Ensembl Genes ENSMUSG00000042451 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000042195 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000141104 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000038445 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000191577 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:53311 UniProtKB/Swiss-Prot
MGD MGI:1858196 ENTREZGENE
NCBI Gene 53311 ENTREZGENE
Pfam fn3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mybph PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt MYBPH_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q148P3_MOUSE UniProtKB/TrEMBL
  Q14AV0_MOUSE UniProtKB/TrEMBL
UniProt Secondary E9QKH7 UniProtKB/Swiss-Prot