Smad1 (SMAD family member 1) - Rat Genome Database

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Gene: Smad1 (SMAD family member 1) Mus musculus
Analyze
Symbol: Smad1
Name: SMAD family member 1
RGD ID: 734156
MGI Page MGI
Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; identical protein binding activity; and nucleic acid binding activity. Involved in several processes, including cell surface receptor protein serine/threonine kinase signaling pathway; osteoblast differentiation; and positive regulation of miRNA transcription. Acts upstream of or within several processes, including brain development; positive regulation of macromolecule biosynthetic process; and skeletal system development. Located in cytoplasm and nucleus. Part of homomeric SMAD protein complex and transcription regulator complex. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human SMAD1 (SMAD family member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI528653; dwarfin-A; dwf-A; Mad; MAD homolog 1; mad-related protein 1; Mad1; Madh; Madh1; Madr1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; mothers against DPP homolog 1; mothers-against-DPP-related 1; MusMLP; Smad 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39880,065,024 - 80,126,057 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl880,065,024 - 80,126,147 (-)EnsemblGRCm39 Ensembl
GRCm38879,338,395 - 79,399,428 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl879,338,395 - 79,399,518 (-)EnsemblGRCm38mm10GRCm38
MGSCv37881,862,294 - 81,923,367 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36882,234,467 - 82,295,540 (-)NCBIMGSCv36mm8
Celera883,615,361 - 83,676,406 (-)NCBICelera
Cytogenetic Map8C1NCBI
cM Map837.56NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroperoxycyclophosphamide  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-methoxypsoralen  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
aucubin  (ISO)
azadirachtin A  (EXP)
benzo[a]pyrene  (EXP)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (EXP)
calciol  (EXP)
captan  (EXP)
carbon nanotube  (EXP)
casticin  (ISO)
CGP 52608  (ISO)
chlordecone  (EXP)
chlorpyrifos  (EXP)
clofibrate  (EXP)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP)
cytochalasin D  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dichlorine  (ISO)
diclofenac  (EXP)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
enzyme inhibitor  (ISO)
fluoxetine  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
galangin  (ISO)
gentamycin  (ISO)
glycerol 2-phosphate  (EXP)
glyphosate  (ISO)
imperatorin  (EXP)
indometacin  (ISO)
isoprenaline  (EXP)
L-ascorbic acid  (EXP)
lead diacetate  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (EXP,ISO)
monocrotaline  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (ISO)
nickel dichloride  (ISO)
nicotine  (EXP)
nonanoic acid  (EXP)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
phenobarbital  (EXP)
picrotoxin  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
raloxifene  (ISO)
resveratrol  (ISO)
rolipram  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
Salidroside  (EXP)
SB 431542  (ISO)
simvastatin  (EXP)
sirtinol  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
Soman  (ISO)
streptozocin  (ISO)
tamoxifen  (EXP)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure morphogenesis  (IBA)
BMP signaling pathway  (IBA,IDA,IGI,IMP,ISO,ISS,TAS)
bone development  (IGI)
cardiac muscle cell proliferation  (IGI,IMP)
cardiac muscle hypertrophy in response to stress  (ISO)
cartilage development  (IGI)
cell differentiation  (IBA)
cell population proliferation  (IMP)
cellular response to organic cyclic compound  (IDA)
DNA-templated transcription  (ISO)
embryonic pattern specification  (ISS)
gamete generation  (IMP)
hindbrain development  (IMP)
homeostatic process  (IMP)
inflammatory response  (IEP)
kidney development  (ISO)
MAPK cascade  (IMP,ISO)
mesodermal cell fate commitment  (IGI)
midbrain development  (IMP)
negative regulation of cell population proliferation  (IMP)
negative regulation of muscle cell apoptotic process  (ISO)
negative regulation of muscle cell differentiation  (IDA)
ossification  (ISO)
osteoblast differentiation  (IDA)
osteoblast fate commitment  (IGI)
positive regulation of cartilage development  (IDA)
positive regulation of cell differentiation  (ISO)
positive regulation of dendrite morphogenesis  (ISO)
positive regulation of gene expression  (IMP)
positive regulation of miRNA transcription  (IMP)
positive regulation of osteoblast differentiation  (IGI)
positive regulation of sprouting angiogenesis  (IEA,ISO)
positive regulation of transcription by RNA polymerase II  (IDA,IGI,IMP,ISO)
protein phosphorylation  (IDA)
regulation of transcription by RNA polymerase II  (IBA,IDA)
response to xenobiotic stimulus  (ISO)
SMAD protein signal transduction  (IBA,IGI,ISO)
stem cell differentiation  (IDA)
transcription by RNA polymerase II  (IDA)
transforming growth factor beta receptor signaling pathway  (IBA,ISO)
ureteric bud development  (IEP)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal allantois morphology  (IAGP)
abnormal cell morphology  (IAGP)
abnormal chorioallantoic fusion  (IAGP)
abnormal chorion morphology  (IAGP)
abnormal cranial nerve morphology  (IAGP)
abnormal decidualization  (IAGP)
abnormal direction of heart looping  (IAGP)
abnormal embryo attachment  (IAGP)
abnormal embryo development  (IAGP)
abnormal embryo turning  (IAGP)
abnormal embryonic epiblast morphology  (IAGP)
abnormal embryonic growth/weight/body size  (IAGP)
abnormal embryonic tissue morphology  (IAGP)
abnormal extraembryonic ectoderm morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal gastric chief cell morphology  (IAGP)
abnormal gastric parietal cell morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart looping  (IAGP)
abnormal heart tube morphology  (IAGP)
abnormal hindbrain morphology  (IAGP)
abnormal left-right axis patterning  (IAGP)
abnormal male reproductive system morphology  (IAGP)
abnormal mesenchyme morphology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal midbrain morphology  (IAGP)
abnormal nervous system development  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal neurocranium morphology  (IAGP)
abnormal pharyngeal arch morphology  (IAGP)
abnormal placenta morphology  (IAGP)
abnormal pregnancy  (IAGP)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal skeleton development  (IAGP)
abnormal somite development  (IAGP)
abnormal spinal nerve morphology  (IAGP)
abnormal stomach epithelium morphology  (IAGP)
abnormal stomach morphology  (IAGP)
abnormal stomach muscularis externa morphology  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal uterine receptivity  (IAGP)
abnormal ventral body wall morphology  (IAGP)
abnormal visceral endoderm morphology  (IAGP)
absent primordial germ cells  (IAGP)
absent second pharyngeal arch  (IAGP)
absent third pharyngeal arch  (IAGP)
absent umbilical cord  (IAGP)
caudal body truncation  (IAGP)
decreased bone trabecula number  (IAGP)
decreased embryo size  (IAGP)
decreased litter size  (IAGP)
decreased osteoblast cell number  (IAGP)
decreased osteoblast proliferation  (IAGP)
decreased primordial germ cell number  (IAGP)
decreased trabecular bone connectivity density  (IAGP)
decreased trabecular bone thickness  (IAGP)
decreased trabecular bone volume  (IAGP)
delayed allantois development  (IAGP)
delayed bone ossification  (IAGP)
delayed embryo implantation  (IAGP)
disorganized embryonic tissue  (IAGP)
disorganized testis cords  (IAGP)
distended pericardium  (IAGP)
early reproductive senescence  (IAGP)
embryonic lethality during organogenesis  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged pericardium  (IAGP)
excessive folding of visceral yolk sac  (IAGP)
failure of chorioallantoic fusion  (IAGP)
failure of heart looping  (IAGP)
female infertility  (IAGP)
heart right ventricle hypertrophy  (IAGP)
hemoperitoneum  (IAGP)
impaired embryo implantation  (IAGP)
impaired osteoblast differentiation  (IAGP)
incomplete embryo turning  (IAGP)
incomplete rostral neuropore closure  (IAGP)
increased bone trabecular spacing  (IAGP)
increased granulosa cell tumor incidence  (IAGP)
increased ovarian carcinoma incidence  (IAGP)
increased ovary tumor incidence  (IAGP)
increased right ventricle systolic pressure  (IAGP)
increased testis tumor incidence  (IAGP)
male infertility  (IAGP)
meteorism  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal lethality  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
reduced female fertility  (IAGP)
reduced fertility  (IAGP)
rostral body truncation  (IAGP)
small testis  (IAGP)
suppressed circulating follicle stimulating hormone level  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Bone morphogenetic protein 4 mediates bile duct ligation induced liver fibrosis through activation of Smad1 and ERK1/2 in rat hepatic stellate cells. Fan J, etal., J Cell Physiol. 2006 May;207(2):499-505.
2. The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways. Fukada T, etal., PLoS One. 2008;3(11):e3642. doi: 10.1371/journal.pone.0003642. Epub 2008 Nov 5.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Chinese herbal formula Qilong-Lishui granule improves puromycin aminonucleoside-induced renal injury through regulation of bone morphogenetic proteins. Li P, etal., Nephrology (Carlton). 2007 Oct;12(5):466-73.
5. [Expression of Smad1 and Smad5 in the testis of infertile rats with kidney-yang deficiency] Ma J, etal., Zhonghua Nan Ke Xue. 2005 Jan;11(1):17-21.
6. Smad1 protects cardiomyocytes from ischemia-reperfusion injury. Masaki M, etal., Circulation. 2005 May 31;111(21):2752-9. Epub 2005 May 23.
7. Expression of Smad1 is directly associated with mesangial matrix expansion in rat diabetic nephropathy. Matsubara T, etal., Lab Invest. 2006 Apr;86(4):357-68.
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. MGD IEA MGD IEA
10. Dysregulated bone morphogenetic protein signaling in monocrotaline-induced pulmonary arterial hypertension. Morty RE, etal., Arterioscler Thromb Vasc Biol. 2007 May;27(5):1072-8. Epub 2007 Mar 8.
11. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
12. Altered expression of Smad family members in injured motor neurons of rat. Okuyama N, etal., Brain Res. 2007 Feb 9;1132(1):36-41. Epub 2006 Dec 12.
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Pangas SA, etal., Mol Cell Biol. 2008 Jan;28(1):248-57. Epub 2007 Oct 29.
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
17. Smad signaling in the rat model of monocrotaline pulmonary hypertension. Ramos MF, etal., Toxicol Pathol. 2008 Feb;36(2):311-20. doi: 10.1177/0192623307311402. Epub 2008 Mar 26.
18. Mouse MP Annotation Import Pipeline RGD automated import pipeline
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension. Takahashi H, etal., Am J Physiol Lung Cell Mol Physiol. 2006 Mar;290(3):L450-8. Epub 2005 Dec 16.
21. Activation of STAT3/Smad1 is a key signaling pathway for progression to glomerulosclerosis in experimental glomerulonephritis. Takahashi T, etal., J Biol Chem. 2005 Feb 25;280(8):7100-6. Epub 2004 Dec 9.
Additional References at PubMed
PMID:7798324   PMID:8799132   PMID:9076678   PMID:9076683   PMID:9451002   PMID:9529255   PMID:9566949   PMID:10079220   PMID:10205054   PMID:10224145   PMID:10349636   PMID:10376010  
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PMID:11714671   PMID:11784053   PMID:11788714   PMID:11811554   PMID:11850197   PMID:11857782   PMID:12082094   PMID:12117821   PMID:12151307   PMID:12217322   PMID:12223402   PMID:12270938  
PMID:12351174   PMID:12370310   PMID:12421925   PMID:12477932   PMID:12520002   PMID:12543979   PMID:12589053   PMID:12665593   PMID:12738770   PMID:12791600   PMID:12799085   PMID:12805214  
PMID:12821673   PMID:12943993   PMID:14500836   PMID:14559231   PMID:14580334   PMID:14610273   PMID:14633973   PMID:14651998   PMID:14656760   PMID:14662776   PMID:14672939   PMID:14681479  
PMID:14711801   PMID:14718543   PMID:14729481   PMID:14732718   PMID:15084259   PMID:15107829   PMID:15123739   PMID:15150273   PMID:15188429   PMID:15196959   PMID:15198985   PMID:15226823  
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PMID:17967138   PMID:18000065   PMID:18003744   PMID:18045539   PMID:18069690   PMID:18087045   PMID:18178801   PMID:18224709   PMID:18243104   PMID:18256193   PMID:18258849   PMID:18272846  
PMID:18285555   PMID:18287559   PMID:18322278   PMID:18329379   PMID:18351662   PMID:18374910   PMID:18395706   PMID:18433296   PMID:18434416   PMID:18446813   PMID:18483623   PMID:18550712  
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PMID:21538804   PMID:21571370   PMID:21613322   PMID:21681813   PMID:21693521   PMID:21723296   PMID:21724602   PMID:21731673   PMID:21778144   PMID:21856951   PMID:21873635   PMID:21880664  
PMID:21896628   PMID:21907140   PMID:21937600   PMID:21939397   PMID:21953618   PMID:21957238   PMID:21976273   PMID:22072987   PMID:22084104   PMID:22114682   PMID:22116936   PMID:22144916  
PMID:22190459   PMID:22240098   PMID:22253716   PMID:22282599   PMID:22300732   PMID:22302143   PMID:22364862   PMID:22365545   PMID:22366192   PMID:22370000   PMID:22426104   PMID:22438570  
PMID:22474288   PMID:22474292   PMID:22485132   PMID:22508726   PMID:22509524   PMID:22510377   PMID:22535663   PMID:22536403   PMID:22547067   PMID:22560297   PMID:22588298   PMID:22609550  
PMID:22632802   PMID:22698281   PMID:22701694   PMID:22711842   PMID:22723422   PMID:22753148   PMID:22783020   PMID:22819676   PMID:22828627   PMID:22833130   PMID:22865640   PMID:22964636  
PMID:22996691   PMID:23011393   PMID:23028455   PMID:23055936   PMID:23064761   PMID:23103586   PMID:23153495   PMID:23169531   PMID:23199293   PMID:23200275   PMID:23203803   PMID:23238123  
PMID:23250216   PMID:23344708   PMID:23360989   PMID:23426374   PMID:23439432   PMID:23458899   PMID:23459943   PMID:23466739   PMID:23469192   PMID:23478097   PMID:23546880   PMID:23559326  
PMID:23560048   PMID:23584254   PMID:23592779   PMID:23595735   PMID:23610558   PMID:23620745   PMID:23665221   PMID:23676271   PMID:23680673   PMID:23712751   PMID:23717575   PMID:23720040  
PMID:23754280   PMID:23776616   PMID:23793844   PMID:23804438   PMID:23863482   PMID:23891934   PMID:23933588   PMID:23946498   PMID:23969857   PMID:23974041   PMID:23993924   PMID:23994637  
PMID:24023003   PMID:24055172   PMID:24067355   PMID:24142423   PMID:24162165   PMID:24211589   PMID:24269886   PMID:24284212   PMID:24293546   PMID:24297369   PMID:24336726   PMID:24347165  
PMID:24373957   PMID:24501377   PMID:24523460   PMID:24524909   PMID:24583261   PMID:24604556   PMID:24680892   PMID:24698271   PMID:24715462   PMID:24816837   PMID:24835278   PMID:24912677  
PMID:24932701   PMID:24933422   PMID:24948604   PMID:24951251   PMID:24952961   PMID:25028519   PMID:25031030   PMID:25034710   PMID:25057208   PMID:25082703   PMID:25100727   PMID:25141865  
PMID:25155999   PMID:25165122   PMID:25182747   PMID:25243859   PMID:25249463   PMID:25274628   PMID:25300579   PMID:25312496   PMID:25318679   PMID:25329657   PMID:25331953   PMID:25336743  
PMID:25376721   PMID:25378163   PMID:25406396   PMID:25428115   PMID:25428587   PMID:25446538   PMID:25470749   PMID:25488669   PMID:25514040   PMID:25536014   PMID:25546423   PMID:25605781  
PMID:25615642   PMID:25670795   PMID:25755279   PMID:25758226   PMID:25762570   PMID:25810530   PMID:25820239   PMID:25870111   PMID:25896202   PMID:25995358   PMID:26023097   PMID:26058470  
PMID:26076038   PMID:26113728   PMID:26116174   PMID:26116176   PMID:26120030   PMID:26173459   PMID:26284287   PMID:26313916   PMID:26317208   PMID:26367869   PMID:26391659   PMID:26407529  
PMID:26466345   PMID:26552887   PMID:26586223   PMID:26658320   PMID:26661618   PMID:26671461   PMID:26681395   PMID:26711875   PMID:26735394   PMID:26739452   PMID:26765568   PMID:26771354  
PMID:26776318   PMID:26821812   PMID:26826495   PMID:26896753   PMID:26952187   PMID:27019229   PMID:27030100   PMID:27048518   PMID:27056911   PMID:27068110   PMID:27076431   PMID:27113717  
PMID:27188281   PMID:27190064   PMID:27217206   PMID:27225772   PMID:27234308   PMID:27250101   PMID:27302476   PMID:27320915   PMID:27335065   PMID:27335460   PMID:27355685   PMID:27381227  
PMID:27483343   PMID:27492138   PMID:27568519   PMID:27596755   PMID:27606421   PMID:27612439   PMID:27633990   PMID:27633992   PMID:27647853   PMID:27680501   PMID:27713395   PMID:27720610  
PMID:27741240   PMID:27803996   PMID:27827819   PMID:27835665   PMID:27890611   PMID:28029182   PMID:28128304   PMID:28190640   PMID:28254784   PMID:28298362   PMID:28327634   PMID:28370465  
PMID:28401685   PMID:28438754   PMID:28457943   PMID:28501478   PMID:28520221   PMID:28574994   PMID:28576771   PMID:28641928   PMID:28642261   PMID:28650075   PMID:28655168   PMID:28692808  
PMID:28763805   PMID:28807898   PMID:28922976   PMID:29093060   PMID:29126155   PMID:29135976   PMID:29151265   PMID:29184513   PMID:29232368   PMID:29247325   PMID:29253505   PMID:29273814  
PMID:29317485   PMID:29321139   PMID:29411501   PMID:29412136   PMID:29463648   PMID:29467244   PMID:29540665   PMID:29618652   PMID:29637597   PMID:29638158   PMID:29665134   PMID:29677202  
PMID:29700203   PMID:29771958   PMID:29852132   PMID:29853617   PMID:29891551   PMID:29934521   PMID:29950483   PMID:29975682   PMID:29981310   PMID:29986157   PMID:30002389   PMID:30125728  
PMID:30134160   PMID:30188920   PMID:30201295   PMID:30230914   PMID:30235284   PMID:30352686   PMID:30413887   PMID:30446626   PMID:30570432   PMID:30638444   PMID:30653268   PMID:30664861  
PMID:30692543   PMID:30735122   PMID:30770380   PMID:30840660   PMID:30842446   PMID:30898767   PMID:30936179   PMID:30958854   PMID:30963569   PMID:31038803   PMID:31127639   PMID:31201465  
PMID:31221640   PMID:31311865   PMID:31539501   PMID:31586065   PMID:31618630   PMID:31670387   PMID:31729356   PMID:31767619   PMID:32078368   PMID:32105214   PMID:32106289   PMID:32142630  
PMID:32156757   PMID:32187534   PMID:32210087   PMID:32324134   PMID:32369449   PMID:32374006   PMID:32467233   PMID:32541003   PMID:32600616   PMID:32616504   PMID:32662771   PMID:32664967  
PMID:32698004   PMID:32720893   PMID:32747435   PMID:32855417   PMID:32866472   PMID:33046507   PMID:33060561   PMID:33217406   PMID:33248111   PMID:33308444   PMID:33372189   PMID:33393086  
PMID:33436499   PMID:33436697   PMID:33463047   PMID:33723039   PMID:33787491   PMID:33846290   PMID:34010654   PMID:34052210   PMID:34062094   PMID:34099644   PMID:34107258   PMID:34129836  
PMID:34157307   PMID:34169608   PMID:34184027   PMID:34184730   PMID:34289374   PMID:34292881   PMID:34321999   PMID:34557486   PMID:34677125   PMID:34719843   PMID:34878095   PMID:34880220  
PMID:34995814   PMID:35020897   PMID:35151207   PMID:35167946   PMID:35194044   PMID:35383354   PMID:35413235   PMID:35503090   PMID:35803228   PMID:35858560   PMID:35877077   PMID:35894043  
PMID:35951005   PMID:35998584   PMID:36067211   PMID:36115458   PMID:36116371   PMID:36257937   PMID:36314682   PMID:36319624   PMID:36370851   PMID:36418715   PMID:36445780   PMID:36566565  
PMID:36680774   PMID:36683433   PMID:36693323   PMID:36715607   PMID:36825302   PMID:36910145   PMID:36915132   PMID:36916392   PMID:36941249   PMID:37024477   PMID:37237002   PMID:37272529  
PMID:37298583   PMID:37300483   PMID:37385754   PMID:37436700   PMID:37577930   PMID:37591240   PMID:37640003   PMID:37680190   PMID:37702066   PMID:37771660   PMID:37869988   PMID:38171360  
PMID:38175868   PMID:38246328   PMID:38300806   PMID:38404688   PMID:38466355   PMID:38632412   PMID:38752427   PMID:38794925   PMID:38951500   PMID:39000154  


Genomics

Comparative Map Data
Smad1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39880,065,024 - 80,126,057 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl880,065,024 - 80,126,147 (-)EnsemblGRCm39 Ensembl
GRCm38879,338,395 - 79,399,428 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl879,338,395 - 79,399,518 (-)EnsemblGRCm38mm10GRCm38
MGSCv37881,862,294 - 81,923,367 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36882,234,467 - 82,295,540 (-)NCBIMGSCv36mm8
Celera883,615,361 - 83,676,406 (-)NCBICelera
Cytogenetic Map8C1NCBI
cM Map837.56NCBI
SMAD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384145,480,770 - 145,559,176 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4145,481,194 - 145,559,176 (+)EnsemblGRCh38hg38GRCh38
GRCh374146,402,458 - 146,480,328 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364146,622,401 - 146,699,778 (+)NCBINCBI36Build 36hg18NCBI36
Build 344146,760,555 - 146,837,928NCBI
Celera4143,730,483 - 143,807,862 (+)NCBICelera
Cytogenetic Map4q31.21NCBI
HuRef4142,134,622 - 142,210,284 (+)NCBIHuRef
CHM1_14146,379,527 - 146,456,909 (+)NCBICHM1_1
T2T-CHM13v2.04148,798,276 - 148,874,991 (+)NCBIT2T-CHM13v2.0
Smad1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81945,417,430 - 45,477,962 (+)NCBIGRCr8
mRatBN7.21928,513,130 - 28,573,665 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1928,513,131 - 28,573,651 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1935,369,097 - 35,429,185 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01936,023,176 - 36,083,272 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01938,258,468 - 38,318,560 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01932,182,942 - 32,248,694 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1932,188,267 - 32,248,684 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01943,079,695 - 43,145,300 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41930,348,886 - 30,409,345 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11930,353,711 - 30,414,170 (+)NCBI
Celera1928,023,055 - 28,083,575 (+)NCBICelera
Cytogenetic Map19q11NCBI
Smad1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554281,361,085 - 1,429,948 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554281,357,398 - 1,429,521 (+)NCBIChiLan1.0ChiLan1.0
SMAD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23143,354,683 - 143,433,135 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14143,753,819 - 143,798,089 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04137,822,269 - 137,899,700 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14149,481,819 - 149,558,135 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4149,481,836 - 149,558,135 (+)Ensemblpanpan1.1panPan2
SMAD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11544,093,491 - 44,171,177 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1544,095,497 - 44,170,098 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1544,485,533 - 44,563,273 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01544,761,101 - 44,839,209 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1544,763,658 - 44,839,222 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11544,034,585 - 44,112,489 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01544,121,557 - 44,199,409 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01544,386,546 - 44,464,496 (+)NCBIUU_Cfam_GSD_1.0
Smad1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530146,145,177 - 46,219,936 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365353,582,489 - 3,657,063 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365353,582,512 - 3,626,312 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMAD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl882,908,527 - 82,968,994 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1882,907,557 - 82,987,909 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SMAD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1792,047,273 - 92,123,451 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl792,079,914 - 92,123,429 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603771,693,446 - 71,769,726 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smad1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248534,444,876 - 4,502,496 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248534,415,816 - 4,503,317 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Smad1
2028 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1206
Count of miRNA genes:650
Interacting mature miRNAs:818
Transcripts:ENSMUST00000066081, ENSMUST00000066091, ENSMUST00000109885
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84809006482090180Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84924559183245673Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined876411976110412125Mouse
14746987Manh64_mmandible shape 64 (mouse)85050595884505958Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined866084397100084549Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85474046188740637Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84809006482090180Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84819016882190288Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85515925889159407Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined871032003105032123Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined876411976110412125Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871740461124622354Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6418673698186736Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86466617698666325Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85050595884505958Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879808806113809031Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85913640493136404Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined876411976110412125Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85629887290298872Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined872122809106123021Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86872247983326976Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86151347995513605Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871829531105829637Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873929123107929226Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7158942790929226Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85233484386334843Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined871032003105032123Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)874126628126826739Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined879245241113245331Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71740461124622354Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined876402145110402251Mouse

Markers in Region
Smad1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38879,371,833 - 79,372,183UniSTSGRCm38
MGSCv37881,895,732 - 81,896,082UniSTSGRCm37
Celera883,648,866 - 83,649,216UniSTS
Cytogenetic Map8C2UniSTS
cM Map8 UniSTS
AI528653  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38879,339,546 - 79,339,627UniSTSGRCm38
MGSCv37881,863,445 - 81,863,526UniSTSGRCm37
Celera883,616,512 - 83,616,593UniSTS
Cytogenetic Map8C2UniSTS
Whitehead/MRC_RH8945.87UniSTS
17.MMHAP23FLF2.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38879,365,903 - 79,366,057UniSTSGRCm38
MGSCv37881,889,802 - 81,889,956UniSTSGRCm37
Celera883,642,936 - 83,643,090UniSTS
Cytogenetic Map8C2UniSTS
Whitehead_YAC8 UniSTS
U74359  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38879,339,290 - 79,339,386UniSTSGRCm38
MGSCv37881,863,189 - 81,863,285UniSTSGRCm37
Celera883,616,256 - 83,616,352UniSTS
Cytogenetic Map8C2UniSTS
Whitehead/MRC_RH8946.99UniSTS
Smad1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38879,355,419 - 79,355,883UniSTSGRCm38
MGSCv37881,879,318 - 81,879,782UniSTSGRCm37
Celera883,632,384 - 83,632,848UniSTS
Cytogenetic Map8C2UniSTS
Smad1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8C2UniSTS
Smad1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8C2UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000066081
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl880,081,985 - 80,126,147 (-)Ensembl
GRCm38.p6 Ensembl879,355,356 - 79,399,518 (-)Ensembl
Ensembl Acc Id: ENSMUST00000066091   ⟹   ENSMUSP00000071035
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl880,065,024 - 80,126,147 (-)Ensembl
GRCm38.p6 Ensembl879,338,395 - 79,399,518 (-)Ensembl
Ensembl Acc Id: ENSMUST00000109885   ⟹   ENSMUSP00000105511
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl880,068,209 - 80,126,147 (-)Ensembl
GRCm38.p6 Ensembl879,341,580 - 79,399,518 (-)Ensembl
Ensembl Acc Id: ENSMUST00000210678
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl880,070,302 - 80,076,680 (-)Ensembl
GRCm38.p6 Ensembl879,343,673 - 79,350,051 (-)Ensembl
Ensembl Acc Id: ENSMUST00000215983
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl880,076,356 - 80,083,307 (-)Ensembl
GRCm38.p6 Ensembl879,349,727 - 79,356,678 (-)Ensembl
RefSeq Acc Id: NM_008539   ⟹   NP_032565
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39880,065,024 - 80,126,057 (-)NCBI
GRCm38879,338,395 - 79,399,428 (-)NCBI
MGSCv37881,862,294 - 81,923,367 (-)RGD
Celera883,615,361 - 83,676,406 (-)RGD
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006530746   ⟹   XP_006530809
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39880,065,024 - 80,099,299 (-)NCBI
GRCm38879,338,409 - 79,372,673 (-)NCBI
Sequence:
RefSeq Acc Id: NP_032565   ⟸   NM_008539
- UniProtKB: Q6GT95 (UniProtKB/Swiss-Prot),   P70442 (UniProtKB/Swiss-Prot),   Q9CYK6 (UniProtKB/Swiss-Prot),   P70340 (UniProtKB/Swiss-Prot),   Q8C3Y6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006530809   ⟸   XM_006530746
- Peptide Label: isoform X1
- UniProtKB: Q6GT95 (UniProtKB/Swiss-Prot),   P70442 (UniProtKB/Swiss-Prot),   Q9CYK6 (UniProtKB/Swiss-Prot),   P70340 (UniProtKB/Swiss-Prot),   Q8C3Y6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000071035   ⟸   ENSMUST00000066091
Ensembl Acc Id: ENSMUSP00000105511   ⟸   ENSMUST00000109885
Protein Domains
MH1   MH2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70340-F1-model_v2 AlphaFold P70340 1-465 view protein structure

Promoters
RGD ID:8667551
Promoter ID:EPDNEW_M11806
Type:initiation region
Name:Smad1_1
Description:Mus musculus SMAD family member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38879,399,428 - 79,399,488EPDNEW
RGD ID:6848896
Promoter ID:MM_TRO:9579
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:MTR002193.8.1414.3
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36881,879,991 - 81,880,491 (-)MPROMDB
RGD ID:6843741
Promoter ID:MM_KWN:54949
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:ENSMUST00000109885,   OTTMUST00000049956,   OTTMUST00000049958
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36881,923,124 - 81,923,624 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109452 AgrOrtholog
Ensembl Genes ENSMUSG00000031681 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000066091 ENTREZGENE
  ENSMUST00000066091.14 UniProtKB/Swiss-Prot
  ENSMUST00000109885.8 UniProtKB/TrEMBL
Gene3D-CATH 2.60.200.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.520.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Dwarfin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAD_homology1_Dwarfin-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAD_homology_MH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMAD-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMAD_dom_Dwarfin-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMAD_MH1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17125 UniProtKB/Swiss-Prot
MGD MGI:109452 ENTREZGENE
NCBI Gene 17125 ENTREZGENE
PANTHER MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13703 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Smad1 PhenoGen
PROSITE MH1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DWA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DWB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49879 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56366 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P70340 ENTREZGENE
  P70442 ENTREZGENE
  Q6GT95 ENTREZGENE
  Q8C3Y6 ENTREZGENE, UniProtKB/TrEMBL
  Q9CYK6 ENTREZGENE
  SMAD1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary P70442 UniProtKB/Swiss-Prot
  Q6GT95 UniProtKB/Swiss-Prot
  Q9CYK6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-10 Smad1  SMAD family member 1  Smad1  MAD homolog 1 (Drosophila)  Symbol and/or name change 5135510 APPROVED