Gabra4 (gamma-aminobutyric acid type A receptor subunit alpha 4) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Gabra4 (gamma-aminobutyric acid type A receptor subunit alpha 4) Mus musculus
Analyze
Symbol: Gabra4
Name: gamma-aminobutyric acid type A receptor subunit alpha 4
RGD ID: 734148
MGI Page MGI
Description: Predicted to enable GABA-gated chloride ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and chloride channel activity. Acts upstream of or within central nervous system development. Predicted to be located in postsynaptic membrane. Predicted to be part of GABA-A receptor complex. Predicted to be active in GABA-ergic synapse; dendrite membrane; and postsynaptic specialization membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and spinal cord. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human GABRA4 (gamma-aminobutyric acid type A receptor subunit alpha4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GABA(A) receptor subunit alpha-4; GABAAR subunit alpha-4; Gabr; Gabra-4; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 4; gamma-aminobutyric acid receptor subunit alpha-4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39571,727,077 - 71,815,651 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl571,727,092 - 71,815,651 (-)EnsemblGRCm39 Ensembl
GRCm38571,569,734 - 71,658,308 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl571,569,749 - 71,658,308 (-)EnsemblGRCm38mm10GRCm38
MGSCv37571,960,973 - 72,049,547 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36571,848,869 - 71,937,443 (-)NCBIMGSCv36mm8
Celera568,834,068 - 68,922,930 (-)NCBICelera
Cytogenetic Map5C3.2NCBI
cM Map538.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
3alpha-hydroxy-5beta-pregnan-20-one  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
amitriptyline  (ISO)
ammonium chloride  (ISO)
androgen antagonist  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzamide  (EXP,ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
Butylparaben  (ISO)
chlorpyrifos  (EXP)
Cuprizon  (ISO)
DDE  (ISO)
delta-hexachlorocyclohexane  (ISO)
diazepam  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dinitrogen oxide  (EXP)
doxorubicin  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
felbamate  (ISO)
fipronil  (ISO)
flumazenil  (ISO)
folic acid  (EXP)
folpet  (EXP)
furosemide  (ISO)
gamma-aminobutyric acid  (EXP,ISO)
isoflurane  (EXP)
isotretinoin  (ISO)
ketoconazole  (ISO)
linuron  (ISO)
lipopolysaccharide  (ISO)
Lorazepam  (ISO)
methylmercury chloride  (EXP)
midazolam  (EXP)
morphine  (EXP)
niclosamide  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pentobarbital  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
picrotoxinin  (ISO)
pioglitazone  (EXP)
pirinixic acid  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
progesterone  (ISO)
propofol  (EXP)
razoxane  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
streptozocin  (EXP)
tacrine  (ISO)
Testosterone propionate  (EXP)
tetrachloromethane  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
vinclozolin  (ISO)
XL147  (EXP)
zaleplon  (ISO)
zolpidem  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Chromosomal mapping of Tmp (Emp1), Xmp (Emp2), and Ymp (Emp3), genes encoding membrane proteins related to Pmp22. Ben-Porath I, etal., Genomics 1998 May 1;49(3):443-7.
2. Investigation of autism and GABA receptor subunit genes in multiple ethnic groups. Collins AL, etal., Neurogenetics. 2006 Jul;7(3):167-74. Epub 2006 Jun 13.
3. mRNA and protein levels for GABAAalpha4, alpha5, beta1 and GABABR1 receptors are altered in brains from subjects with autism. Fatemi SH, etal., J Autism Dev Disord. 2010 Jun;40(6):743-50.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Cloning, pharmacological characteristics and expression pattern of the rat GABAA receptor alpha 4 subunit. Wisden W, etal., FEBS Lett 1991 Sep 9;289(2):227-30.
Additional References at PubMed
PMID:2556293   PMID:7560270   PMID:7920633   PMID:8390964   PMID:8747928   PMID:8889548   PMID:9457670   PMID:9924185   PMID:10078620   PMID:10349636   PMID:10479684   PMID:10843805  
PMID:11042159   PMID:11076861   PMID:12477932   PMID:15265862   PMID:16141072   PMID:16141073   PMID:16987237   PMID:17005728   PMID:17159992   PMID:17698926   PMID:18185516   PMID:18287559  
PMID:18985723   PMID:19923508   PMID:20018248   PMID:20299596   PMID:20457185   PMID:21267068   PMID:21722213   PMID:21789198   PMID:21873635   PMID:21977012   PMID:22418059   PMID:22569571  
PMID:22640814   PMID:22723691   PMID:22753476   PMID:22768092   PMID:22815831   PMID:23948640   PMID:24027285   PMID:24062179   PMID:24431441   PMID:24886120   PMID:24948817   PMID:24952961  
PMID:25131634   PMID:25556800   PMID:25708312   PMID:26357588   PMID:26826007   PMID:27136678   PMID:28473323   PMID:29684457   PMID:30496825   PMID:31138677   PMID:32033586   PMID:32579924  
PMID:34702942   PMID:35355020   PMID:36460641   PMID:37553242   PMID:38894703   PMID:39305123  


Genomics

Comparative Map Data
Gabra4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39571,727,077 - 71,815,651 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl571,727,092 - 71,815,651 (-)EnsemblGRCm39 Ensembl
GRCm38571,569,734 - 71,658,308 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl571,569,749 - 71,658,308 (-)EnsemblGRCm38mm10GRCm38
MGSCv37571,960,973 - 72,049,547 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36571,848,869 - 71,937,443 (-)NCBIMGSCv36mm8
Celera568,834,068 - 68,922,930 (-)NCBICelera
Cytogenetic Map5C3.2NCBI
cM Map538.08NCBI
GABRA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38446,918,900 - 46,993,581 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl446,918,900 - 46,993,581 (-)EnsemblGRCh38hg38GRCh38
GRCh37446,920,917 - 46,995,598 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36446,615,674 - 46,690,337 (-)NCBINCBI36Build 36hg18NCBI36
Build 34446,761,846 - 46,836,508NCBI
Celera447,369,879 - 47,444,600 (-)NCBICelera
Cytogenetic Map4p12NCBI
HuRef446,239,865 - 46,315,415 (-)NCBIHuRef
CHM1_1446,920,103 - 46,995,631 (-)NCBICHM1_1
T2T-CHM13v2.0446,886,225 - 46,960,936 (-)NCBIT2T-CHM13v2.0
Gabra4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81436,944,747 - 37,021,652 (+)NCBIGRCr8
mRatBN7.21436,590,782 - 36,667,724 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1436,590,782 - 36,665,844 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1436,935,370 - 37,010,517 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01438,240,130 - 38,315,273 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01436,728,476 - 36,803,610 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01439,154,072 - 39,230,994 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1439,154,529 - 39,231,695 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01438,966,016 - 39,040,606 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41439,047,461 - 39,122,531 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11439,049,851 - 39,124,917 (+)NCBI
Celera1435,813,603 - 35,888,671 (+)NCBICelera
Cytogenetic Map14p11NCBI
Gabra4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554431,564,202 - 1,632,580 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554431,564,794 - 1,631,975 (+)NCBIChiLan1.0ChiLan1.0
GABRA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2380,876,574 - 80,952,059 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1481,138,247 - 81,213,682 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0475,163,796 - 75,240,049 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1485,894,401 - 85,970,077 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl485,894,401 - 85,960,783 (+)Ensemblpanpan1.1panPan2
GABRA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11342,889,100 - 42,958,604 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1342,897,655 - 42,959,206 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1342,690,028 - 42,908,686 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01343,345,979 - 43,564,367 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1343,500,264 - 43,565,899 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11343,023,386 - 43,242,431 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01343,085,285 - 43,303,834 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01343,439,087 - 43,657,538 (-)NCBIUU_Cfam_GSD_1.0
Gabra4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528533,123,748 - 33,190,987 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648213,109,803 - 13,174,492 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648213,109,803 - 13,174,492 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABRA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl836,874,331 - 36,942,773 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1836,875,649 - 36,943,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2838,744,693 - 38,811,740 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GABRA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1273,253,789 - 3,323,102 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl273,254,735 - 3,321,128 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604749,315,895 - 49,393,069 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabra4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476120,071,316 - 20,132,098 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476120,071,343 - 20,132,523 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gabra4
4418 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:767
Count of miRNA genes:442
Interacting mature miRNAs:552
Transcripts:ENSMUST00000031121
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56024608194246203Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56265056896650688Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
1300951Gbvq1_mgallstone bladder volume QTL 1 (mouse)Not determined53811168172111798Mouse
14746981Manh57_mmandible shape 57 (mouse)54716974281169742Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563705442104387065Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
1301698Pcfm4_mperiosteal circumference and femur length 4 (mouse)Not determined54458584378585965Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566529661100529661Mouse
10043962Obq27_mobesity QTL 27 (mouse)Not determined55628565590285655Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6265056896650688Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55960280193602980Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55960280193602980Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55960280193602980Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566529661100529661Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555388334100455525Mouse
13207584Mwmlpt4_mMorris water maze latency to platform, training, 4 (mouse)54632260680322606Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
13207588Mwmlpa4_mMorris water maze latency to platform, all, 4 (mouse)54632260680322606Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56437487798374996Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
13464248Ahl13_mage related hearing loss, early onset 13 (mouse)55564587489645995Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56265056896650688Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56265056896650688Mouse
13464245Ahl12_mage related hearing loss, early onset 12 (mouse)53811168172111798Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55960280193602980Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56040306294403160Mouse
10044005Ahl7_mage related hearing loss 7 (mouse)Not determined55833050292330641Mouse

Markers in Region
Gabra4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37572,032,458 - 72,033,523UniSTSGRCm37
Celera568,905,841 - 68,906,906UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map5 UniSTS
D5Buc33  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38571,641,126 - 71,642,304UniSTSGRCm38
MGSCv37572,032,365 - 72,033,543UniSTSGRCm37
Celera568,905,748 - 68,906,926UniSTS
Cytogenetic Map5C3.2UniSTS
cM Map540.0UniSTS
Gabra4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5C3.2UniSTS
cM Map5 UniSTS
Gabra4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38571,641,219 - 71,642,284UniSTSGRCm38
MGSCv37572,032,458 - 72,033,523UniSTSGRCm37
Celera568,905,841 - 68,906,906UniSTS
Cytogenetic Map5C3.2UniSTS
Gabra4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5C3.2UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001359041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001359050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC163437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF090373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000031121   ⟹   ENSMUSP00000031121
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl571,727,092 - 71,815,651 (-)Ensembl
GRCm38.p6 Ensembl571,569,749 - 71,658,308 (-)Ensembl
Ensembl Acc Id: ENSMUST00000197994   ⟹   ENSMUSP00000143063
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl571,728,949 - 71,815,233 (-)Ensembl
GRCm38.p6 Ensembl571,571,606 - 71,657,890 (-)Ensembl
Ensembl Acc Id: ENSMUST00000198138   ⟹   ENSMUSP00000142466
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl571,729,398 - 71,815,218 (-)Ensembl
GRCm38.p6 Ensembl571,572,055 - 71,657,875 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199150
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl571,812,539 - 71,815,163 (-)Ensembl
GRCm38.p6 Ensembl571,655,196 - 71,657,820 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199357   ⟹   ENSMUSP00000143675
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl571,728,544 - 71,815,324 (-)Ensembl
GRCm38.p6 Ensembl571,571,201 - 71,657,981 (-)Ensembl
RefSeq Acc Id: NM_001359041   ⟹   NP_001345970
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,727,077 - 71,815,651 (-)NCBI
GRCm38571,569,734 - 71,658,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359043   ⟹   NP_001345972
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,727,077 - 71,815,651 (-)NCBI
GRCm38571,569,734 - 71,658,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359044   ⟹   NP_001345973
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,727,077 - 71,815,651 (-)NCBI
GRCm38571,569,734 - 71,658,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359045   ⟹   NP_001345974
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,727,077 - 71,815,651 (-)NCBI
GRCm38571,569,734 - 71,658,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359046   ⟹   NP_001345975
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,727,077 - 71,815,651 (-)NCBI
GRCm38571,569,734 - 71,658,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359047   ⟹   NP_001345976
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,727,077 - 71,815,651 (-)NCBI
GRCm38571,569,734 - 71,658,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359048   ⟹   NP_001345977
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,727,077 - 71,815,651 (-)NCBI
GRCm38571,569,734 - 71,658,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001359050   ⟹   NP_001345979
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,727,077 - 71,815,651 (-)NCBI
GRCm38571,569,734 - 71,658,308 (-)NCBI
Sequence:
RefSeq Acc Id: NM_010251   ⟹   NP_034381
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39571,727,077 - 71,815,651 (-)NCBI
GRCm38571,569,734 - 71,658,308 (-)NCBI
MGSCv37571,960,973 - 72,049,547 (-)RGD
Celera568,834,068 - 68,922,930 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034381   ⟸   NM_010251
- Peptide Label: isoform 2 precursor
- UniProtKB: Q9D6F4 (UniProtKB/Swiss-Prot),   Q543Z0 (UniProtKB/TrEMBL),   Q3URE7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001345979   ⟸   NM_001359050
- Peptide Label: isoform 9 precursor
- UniProtKB: A0A0G2JDR1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001345973   ⟸   NM_001359044
- Peptide Label: isoform 4 precursor
RefSeq Acc Id: NP_001345972   ⟸   NM_001359043
- Peptide Label: isoform 3
- UniProtKB: Q3URE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001345977   ⟸   NM_001359048
- Peptide Label: isoform 8 precursor
- UniProtKB: Q3TRC7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001345976   ⟸   NM_001359047
- Peptide Label: isoform 7 precursor
- UniProtKB: Q3TRC7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001345975   ⟸   NM_001359046
- Peptide Label: isoform 6 precursor
- UniProtKB: Q3TRC7 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001345974   ⟸   NM_001359045
- Peptide Label: isoform 5 precursor
RefSeq Acc Id: NP_001345970   ⟸   NM_001359041
- Peptide Label: isoform 1 precursor
- UniProtKB: Q3USX9 (UniProtKB/TrEMBL),   Q3URE7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000142466   ⟸   ENSMUST00000198138
Ensembl Acc Id: ENSMUSP00000143063   ⟸   ENSMUST00000197994
Ensembl Acc Id: ENSMUSP00000031121   ⟸   ENSMUST00000031121
Ensembl Acc Id: ENSMUSP00000143675   ⟸   ENSMUST00000199357
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding   Neurotransmitter-gated ion-channel transmembrane

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9D6F4-F1-model_v2 AlphaFold Q9D6F4 1-552 view protein structure

Promoters
RGD ID:6886838
Promoter ID:EPDNEW_M6870
Type:initiation region
Name:Gabra4_1
Description:Mus musculus gamma-aminobutyric acid A receptor, subunit alpha4 , transcript variant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6871  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38571,657,893 - 71,657,953EPDNEW
RGD ID:6886840
Promoter ID:EPDNEW_M6871
Type:initiation region
Name:Gabra4_2
Description:Mus musculus gamma-aminobutyric acid A receptor, subunit alpha4 , transcript variant 5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M6870  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38571,658,308 - 71,658,368EPDNEW
RGD ID:6837551
Promoter ID:MM_KWN:42501
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_010251,   UC008XQZ.1,   UC008XRA.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36572,048,961 - 72,049,461 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95616 AgrOrtholog
Ensembl Genes ENSMUSG00000029211 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000031121 ENTREZGENE
  ENSMUST00000031121.10 UniProtKB/Swiss-Prot
  ENSMUST00000197994.2 UniProtKB/TrEMBL
  ENSMUST00000198138 ENTREZGENE
  ENSMUST00000198138.2 UniProtKB/TrEMBL
  ENSMUST00000199357 ENTREZGENE
  ENSMUST00000199357.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GABAA/Glycine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABAAa_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABBAa4_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gabra-1-6_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_channel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14397 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95616 ENTREZGENE
NCBI Gene 14397 ENTREZGENE
PANTHER GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18945 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gabra4 PhenoGen
PRINTS GABAARALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABAARALPHA4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABAARECEPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JDR1 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JF83_MOUSE UniProtKB/TrEMBL
  GBRA4_MOUSE UniProtKB/Swiss-Prot
  O88963_MOUSE UniProtKB/TrEMBL
  Q3TRC7 ENTREZGENE, UniProtKB/TrEMBL
  Q3URE7 ENTREZGENE, UniProtKB/TrEMBL
  Q3USX9 ENTREZGENE, UniProtKB/TrEMBL
  Q543Z0 ENTREZGENE, UniProtKB/TrEMBL
  Q9D6F4 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Gabra4  gamma-aminobutyric acid type A receptor subunit alpha 4  Gabra4  gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4  Symbol and/or name change 5135510 APPROVED