CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2) - Rat Genome Database

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Gene: CITED2 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2) Homo sapiens
Analyze
Symbol: CITED2
Name: Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
RGD ID: 734120
HGNC Page HGNC:1987
Description: Enables several functions, including LBD domain binding activity; histone acetyltransferase binding activity; and transcription coactivator activity. Involved in several processes, including positive regulation of peroxisome proliferator activated receptor signaling pathway; regulation of gene expression; and response to estrogen. Located in cytoplasm and nucleus. Part of protein-containing complex. Implicated in atrial heart septal defect 8 and ventricular septal defect.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ASD8; cbp/p300-interacting transactivator 2; Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; melanocyte-specific gene 1-related gene 1; MRG-1; MRG1; MSG-related protein 1; MSG1-related gene 1; P35SRJ; VSD2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386139,371,807 - 139,374,648 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6139,371,807 - 139,374,648 (-)EnsemblGRCh38hg38GRCh38
GRCh376139,692,944 - 139,695,785 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366139,735,089 - 139,737,478 (-)NCBINCBI36Build 36hg18NCBI36
Build 346139,735,088 - 139,737,478NCBI
Celera6140,433,459 - 140,435,848 (-)NCBICelera
Cytogenetic Map6q24.1NCBI
HuRef6137,254,618 - 137,257,015 (-)NCBIHuRef
CHM1_16139,956,432 - 139,958,827 (-)NCBICHM1_1
T2T-CHM13v2.06140,555,711 - 140,558,549 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (EXP)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
aristolochic acid A  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
azoxystrobin  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
buta-1,3-diene  (ISO)
butan-1-ol  (EXP)
C60 fullerene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
carboplatin  (ISO)
cefaloridine  (ISO)
celastrol  (EXP)
CGP 52608  (EXP)
chlorpromazine  (ISO)
chrysene  (ISO)
ciglitazone  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (EXP)
coumestrol  (EXP)
crocidolite asbestos  (EXP)
cycloheximide  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cytarabine  (EXP)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (EXP)
dibutyl phthalate  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
diuron  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
Enterolactone  (EXP)
entinostat  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
flavonoids  (ISO)
flurbiprofen  (ISO)
flutamide  (ISO)
folic acid  (ISO)
formaldehyde  (EXP)
fulvestrant  (EXP)
furan  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gedunin  (EXP)
genistein  (EXP)
gentamycin  (ISO)
hydrogen peroxide  (EXP)
indometacin  (EXP)
isoprenaline  (ISO)
kainic acid  (ISO)
kenpaullone  (ISO)
leflunomide  (EXP,ISO)
Licochalcone B  (EXP)
lipopolysaccharide  (ISO)
menadione  (EXP)
methamphetamine  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (EXP)
methylmercury(1+)  (ISO)
Muraglitazar  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (EXP)
nimesulide  (ISO)
panobinostat  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP,ISO)
quercetin  (EXP)
reactive oxygen species  (EXP)
resorcinol  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
SB 431542  (EXP)
silicon dioxide  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (EXP)
Soman  (ISO)
streptozocin  (EXP,ISO)
sulforaphane  (EXP)
tamoxifen  (EXP,ISO)
tauroursodeoxycholic acid  (ISO)
testosterone  (EXP,ISO)
tetraphene  (ISO)
thimerosal  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topiramate  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
troglitazone  (ISO)
urethane  (EXP)
ursodeoxycholic acid  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)
vinclozolin  (ISO)
WIN 55212-2  (ISO)
zinc atom  (EXP)
zinc dichloride  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adrenal cortex formation  (IEA,ISS)
adrenal gland development  (IEA,ISO)
blood vessel development  (IEA,ISO)
bone morphogenesis  (IEA,ISO)
branching involved in ureteric bud morphogenesis  (ISO)
cardiac neural crest cell development involved in heart development  (IEA,ISO)
cardiac septum morphogenesis  (IEA,ISO)
cell differentiation  (IEA)
cell population proliferation  (IDA)
cellular response to growth factor stimulus  (IEA,ISO)
cellular senescence  (IEA,ISO)
central nervous system development  (IEA,ISO)
cranial nerve morphogenesis  (IEA,ISO)
decidualization  (IEA,ISO)
determination of heart left/right asymmetry  (IEA,ISO)
determination of left/right symmetry  (IEA,ISS)
embryonic camera-type eye morphogenesis  (IEA,ISO)
embryonic heart tube left/right pattern formation  (IEA,ISS)
embryonic placenta development  (IEA,ISO)
embryonic process involved in female pregnancy  (IEA,ISO)
endocardial cushion development  (IEA,ISO)
erythrocyte development  (IEA,ISO)
granulocyte differentiation  (IEA,ISO)
heart development  (IEA,IMP,ISS)
heart looping  (IEA,ISO)
hematopoietic progenitor cell differentiation  (IEA,ISO)
in utero embryonic development  (IEA,ISO)
kidney development  (ISO)
left/right axis specification  (IEA,ISS)
left/right pattern formation  (IBA)
lens morphogenesis in camera-type eye  (IEA,ISO)
leukocyte differentiation  (IEA,ISO)
liver development  (IEA,ISO,ISS)
male gonad development  (IEA,ISO)
morphogenesis of an epithelium  (ISO)
negative regulation of apoptotic process  (IEA,ISS)
negative regulation of cardiac muscle cell proliferation  (IEA)
negative regulation of cell migration  (IMP)
negative regulation of DNA-templated transcription  (IDA,IMP)
negative regulation of gene expression  (IDA,IEA)
negative regulation of transcription by RNA polymerase II  (IMP)
negative regulation of transcription from RNA polymerase II promoter in response to hypoxia  (IDA)
neural tube closure  (IEA,ISO)
neural tube formation  (IEA,ISO)
nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry  (IEA,ISS)
outflow tract morphogenesis  (IEA,ISO,ISS)
peripheral nervous system development  (IEA,ISO)
positive regulation of cell cycle  (IEA,ISS)
positive regulation of cell-cell adhesion  (IEA,ISS)
positive regulation of DNA-templated transcription  (IDA,IEA,ISS)
positive regulation of gene expression  (IDA,IEA)
positive regulation of male gonad development  (IEA,ISS)
positive regulation of peroxisome proliferator activated receptor signaling pathway  (IDA)
positive regulation of transcription by RNA polymerase II  (IDA,IEA,ISS)
positive regulation of transforming growth factor beta receptor signaling pathway  (IEA,ISS)
pulmonary artery morphogenesis  (IEA,ISO)
regulation of animal organ formation  (IEA,ISS)
regulation of DNA-templated transcription  (IEA)
regulation of transcription by RNA polymerase II  (IEA,ISO)
response to estrogen  (IDA)
response to fluid shear stress  (IMP)
response to hypoxia  (IDA,IMP)
response to mechanical stimulus  (IEA,ISO)
sex determination  (IBA,IEA,ISS)
skeletal muscle cell differentiation  (IEA,ISO)
spleen development  (IEA,ISS)
thymus development  (IEA,ISO)
transforming growth factor beta receptor signaling pathway  (IEA,ISO)
trophectodermal cell differentiation  (IEA,ISO)
vasculature development  (IEA,ISO)
vasculogenesis  (IEA,ISO)
ventricular septum development  (IEA,ISO)
ventricular septum morphogenesis  (IEA,ISS)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abnormal left ventricular function  (IAGP)
Abnormal mitral valve morphology  (IAGP)
Abnormal nasal morphology  (IAGP)
Airway obstruction  (IAGP)
Anomalous pulmonary venous return  (IAGP)
Arrhythmia  (IAGP)
Atrial arrhythmia  (IAGP)
Atrial fibrillation  (IAGP)
Atrial flutter  (IAGP)
Atrial septal defect  (IAGP)
Automatic atrial tachycardia  (IAGP)
Autosomal dominant inheritance  (IAGP)
Brachydactyly  (IAGP)
Breathing dysregulation  (IAGP)
Broad forehead  (IAGP)
Bundle branch block  (IAGP)
Cardiac conduction abnormality  (IAGP)
Clinodactyly of the 5th finger  (IAGP)
Congenital onset  (IAGP)
Congestive heart failure  (IAGP)
Cryptorchidism  (IAGP)
Cyanosis  (IAGP)
Dolichocephaly  (IAGP)
Dyspnea  (IAGP)
Exercise intolerance  (IAGP)
Exertional dyspnea  (IAGP)
Fatigue  (IAGP)
First degree atrioventricular block  (IAGP)
Increased pulmonary vascular resistance  (IAGP)
Intrauterine growth retardation  (IAGP)
Junctional ectopic tachycardia  (IAGP)
Left-to-right shunt  (IAGP)
Mitral regurgitation  (IAGP)
Orthopnea  (IAGP)
Palpitations  (IAGP)
Paradoxical splitting of the second heart sound  (IAGP)
Pedal edema  (IAGP)
Perimembranous ventricular septal defect  (IAGP)
Pneumonia  (IAGP)
Preauricular pit  (IAGP)
Premature atrial contractions  (IAGP)
Proptosis  (IAGP)
Pulmonary arterial hypertension  (IAGP)
Recurrent bacterial infections  (IAGP)
Right atrial enlargement  (IAGP)
Right bundle branch block  (IAGP)
Right ventricular dilatation  (IAGP)
Right ventricular failure  (IAGP)
ST segment depression  (IAGP)
Stroke  (IAGP)
Supraventricular arrhythmia  (IAGP)
Supraventricular tachycardia  (IAGP)
Syncope  (IAGP)
Systolic heart murmur  (IAGP)
Tetralogy of Fallot  (IAGP)
Thin vermilion border  (IAGP)
Thromboembolism  (IAGP)
Transient ischemic attack  (IAGP)
Tricuspid regurgitation  (IAGP)
Underdeveloped supraorbital ridges  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Folic acid prevents exencephaly in Cited2 deficient mice. Barbera JP, etal., Hum Mol Genet 2002 Feb 1;11(3):283-93.
2. Silencing of Cited2 and Akap12 genes in radiation-induced rat osteosarcomas. Daino K, etal., Biochem Biophys Res Commun. 2009 Dec 18;390(3):654-8. Epub 2009 Oct 13.
3. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
4. Identification of CITED2 as a negative regulator of fracture healing. Lee JY, etal., Biochem Biophys Res Commun. 2009 Oct 2;387(4):641-5. Epub 2009 Jul 14.
5. Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1. Leung MK, etal., Genomics 1999 Nov 1;61(3):307-13.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
11. Induction of CITED2 expression in the rat hippocampus following transient global ischemia. Sun W, etal., Brain Res. 2006 Feb 9;1072(1):15-8. Epub 2006 Jan 24.
Additional References at PubMed
PMID:8889548   PMID:8901575   PMID:9434189   PMID:9811838   PMID:9887100   PMID:10593900   PMID:11581164   PMID:11597177   PMID:11694877   PMID:11744733   PMID:12477932   PMID:12586840  
PMID:12762840   PMID:12778114   PMID:12960175   PMID:14594809   PMID:14633989   PMID:15051727   PMID:15154850   PMID:15489334   PMID:16287139   PMID:16341674   PMID:16619037   PMID:16675452  
PMID:17906695   PMID:17932483   PMID:18054336   PMID:18984668   PMID:19319572   PMID:19322201   PMID:19642106   PMID:19862010   PMID:19904269   PMID:20139978   PMID:20392269   PMID:20654020  
PMID:20686565   PMID:20932315   PMID:21098220   PMID:21165656   PMID:21660965   PMID:21873635   PMID:22075993   PMID:22709740   PMID:22735262   PMID:22814619   PMID:23082118   PMID:23212831  
PMID:23222517   PMID:23251661   PMID:23263863   PMID:23720494   PMID:23811274   PMID:24097068   PMID:24456003   PMID:24848765   PMID:25184385   PMID:25956243   PMID:26496610   PMID:26812245  
PMID:26851278   PMID:26972000   PMID:27627783   PMID:27680315   PMID:28008154   PMID:28084522   PMID:28273070   PMID:28436679   PMID:28501104   PMID:28687891   PMID:29072699   PMID:29180619  
PMID:29203644   PMID:29787114   PMID:30177819   PMID:30291252   PMID:30628655   PMID:30891766   PMID:30986495   PMID:31515672   PMID:32814053   PMID:33439552   PMID:33691475   PMID:33706167  
PMID:33961781   PMID:35789404   PMID:36626551  


Genomics

Comparative Map Data
CITED2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386139,371,807 - 139,374,648 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6139,371,807 - 139,374,648 (-)EnsemblGRCh38hg38GRCh38
GRCh376139,692,944 - 139,695,785 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366139,735,089 - 139,737,478 (-)NCBINCBI36Build 36hg18NCBI36
Build 346139,735,088 - 139,737,478NCBI
Celera6140,433,459 - 140,435,848 (-)NCBICelera
Cytogenetic Map6q24.1NCBI
HuRef6137,254,618 - 137,257,015 (-)NCBIHuRef
CHM1_16139,956,432 - 139,958,827 (-)NCBICHM1_1
T2T-CHM13v2.06140,555,711 - 140,558,549 (-)NCBIT2T-CHM13v2.0
Cited2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391017,598,452 - 17,601,422 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1017,598,966 - 17,601,422 (+)EnsemblGRCm39 Ensembl
GRCm381017,723,228 - 17,725,674 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1017,723,218 - 17,725,674 (+)EnsemblGRCm38mm10GRCm38
MGSCv371017,443,034 - 17,445,480 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361017,412,662 - 17,415,072 (+)NCBIMGSCv36mm8
Celera1017,602,360 - 17,604,805 (+)NCBICelera
Cytogenetic Map10A2NCBI
Cited2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2112,312,426 - 12,314,869 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl112,312,160 - 12,314,897 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx112,084,290 - 12,086,734 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0118,086,206 - 18,088,650 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0112,292,779 - 12,295,222 (+)NCBIRnor_WKY
Rnor_6.0112,823,363 - 12,825,806 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl112,823,363 - 12,825,786 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0114,515,629 - 14,518,072 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4112,721,500 - 12,723,943 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1112,721,561 - 12,724,003 (+)NCBI
Celera110,778,037 - 10,780,480 (+)NCBICelera
Cytogenetic Map1p12NCBI
Cited2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543620,370,950 - 20,372,677 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543620,370,950 - 20,372,677 (+)NCBIChiLan1.0ChiLan1.0
CITED2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan16157,233,726 - 157,236,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06137,134,142 - 137,136,550 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16141,213,671 - 141,215,919 (-)NCBIpanpan1.1PanPan1.1panPan2
CITED2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1131,522,911 - 31,525,342 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl131,523,799 - 31,524,995 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha132,396,275 - 32,398,722 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0131,684,411 - 31,686,856 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl131,685,298 - 31,686,119 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1131,559,687 - 31,562,137 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0131,442,285 - 31,444,731 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0131,753,743 - 31,756,214 (-)NCBIUU_Cfam_GSD_1.0
Cited2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946126,574,685 - 126,577,867 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365606,354,338 - 6,356,735 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365606,353,901 - 6,356,749 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CITED2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl125,155,664 - 25,160,279 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1125,155,652 - 25,158,517 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2128,295,042 - 28,297,457 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CITED2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11334,009,527 - 34,011,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1334,010,228 - 34,011,046 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660406,152,738 - 6,155,148 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cited2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475314,630,827 - 14,632,536 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475314,630,842 - 14,633,245 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CITED2
30 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_006079.5(CITED2):c.510_536del (p.163GSSTPGGSG[1]) deletion Ventricular septal defect 2 [RCV000007113] Chr6:139373409..139373435 [GRCh38]
Chr6:139694546..139694572 [GRCh37]
Chr6:6q24.1		 pathogenic
CITED2, 27-BP INS, NT534 insertion Atrial septal defect 8 [RCV000007114] Chr6:6q23.3 pathogenic
NM_006079.5(CITED2):c.581GCGGCA[2] (p.196SG[1]) microsatellite Atrial septal defect 8 [RCV000007115]|not provided [RCV002259303] Chr6:139373347..139373352 [GRCh38]
Chr6:139694484..139694489 [GRCh37]
Chr6:6q24.1		 pathogenic|likely benign
GRCh38/hg38 6q23.3-25.3(chr6:135358150-155455117)x3 copy number gain See cases [RCV000136826] Chr6:135358150..155455117 [GRCh38]
Chr6:135679288..155776251 [GRCh37]
Chr6:135720981..155817943 [NCBI36]
Chr6:6q23.3-25.3		 pathogenic
GRCh38/hg38 6q24.1(chr6:139002616-140199336)x3 copy number gain See cases [RCV000137989] Chr6:139002616..140199336 [GRCh38]
Chr6:139323753..140520473 [GRCh37]
Chr6:139365446..140562166 [NCBI36]
Chr6:6q24.1		 uncertain significance
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3 copy number gain See cases [RCV000139729] Chr6:74382807..142040500 [GRCh38]
Chr6:75092523..142361637 [GRCh37]
Chr6:75149243..142403330 [NCBI36]
Chr6:6q13-24.1		 pathogenic
GRCh38/hg38 6q23.2-27(chr6:133537271-165875545)x3 copy number gain See cases [RCV000143444] Chr6:133537271..165875545 [GRCh38]
Chr6:133858409..166289033 [GRCh37]
Chr6:133900102..166209023 [NCBI36]
Chr6:6q23.2-27		 pathogenic
NM_006079.5(CITED2):c.788AGC[3] (p.Gln264dup) microsatellite not provided [RCV000487795] Chr6:139373151..139373152 [GRCh38]
Chr6:139694288..139694289 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.74C>T (p.Ala25Val) single nucleotide variant not provided [RCV000524032] Chr6:139373871 [GRCh38]
Chr6:139695008 [GRCh37]
Chr6:6q24.1		 uncertain significance
GRCh37/hg19 6q24.1(chr6:139645294-139719712)x1 copy number loss See cases [RCV000446971] Chr6:139645294..139719712 [GRCh37]
Chr6:6q24.1		 uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6q23.2-24.2(chr6:133077239-143761582)x1 copy number loss See cases [RCV000510451] Chr6:133077239..143761582 [GRCh37]
Chr6:6q23.2-24.2		 pathogenic
GRCh37/hg19 6q24.1-25.1(chr6:139513020-150389231)x1 copy number loss See cases [RCV000510942] Chr6:139513020..150389231 [GRCh37]
Chr6:6q24.1-25.1		 pathogenic
NM_006079.5(CITED2):c.479A>T (p.His160Leu) single nucleotide variant not provided [RCV000971892]|not specified [RCV000678701] Chr6:139373466 [GRCh38]
Chr6:139694603 [GRCh37]
Chr6:6q24.1		 likely benign|uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
NM_006079.5(CITED2):c.657C>T (p.Asp219=) single nucleotide variant not provided [RCV000968603] Chr6:139373288 [GRCh38]
Chr6:139694425 [GRCh37]
Chr6:6q24.1		 benign
NM_006079.5(CITED2):c.27C>T (p.Asn9=) single nucleotide variant not provided [RCV000922681] Chr6:139373918 [GRCh38]
Chr6:139695055 [GRCh37]
Chr6:6q24.1		 likely benign
GRCh37/hg19 6q23.3-24.3(chr6:135239633-146997510) copy number loss not provided [RCV000767713] Chr6:135239633..146997510 [GRCh37]
Chr6:6q23.3-24.3		 pathogenic
NM_006079.5(CITED2):c.12T>C (p.His4=) single nucleotide variant not provided [RCV000970146] Chr6:139373933 [GRCh38]
Chr6:139695070 [GRCh37]
Chr6:6q24.1		 benign
NM_006079.5(CITED2):c.581GCGGCA[2] (p.196SG[1]) microsatellite not provided [RCV000970457] Chr6:139373347..139373352 [GRCh38]
Chr6:139694484..139694489 [GRCh37]
Chr6:6q24.1		 likely benign
GRCh37/hg19 6q23.2-24.1(chr6:133817341-140038401)x1 copy number loss not provided [RCV001005848] Chr6:133817341..140038401 [GRCh37]
Chr6:6q23.2-24.1		 pathogenic
NM_006079.5(CITED2):c.574A>G (p.Ser192Gly) single nucleotide variant not provided [RCV000827195] Chr6:139373371 [GRCh38]
Chr6:139694508 [GRCh37]
Chr6:6q24.1		 benign|likely benign
NM_006079.5(CITED2):c.701A>C (p.Glu234Ala) single nucleotide variant Atrial septal defect 8 [RCV000991200] Chr6:139373244 [GRCh38]
Chr6:139694381 [GRCh37]
Chr6:6q24.1		 likely pathogenic
NM_006079.5(CITED2):c.382C>T (p.Pro128Ser) single nucleotide variant not specified [RCV001195602] Chr6:139373563 [GRCh38]
Chr6:139694700 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.627C>T (p.Pro209=) single nucleotide variant not provided [RCV000908356] Chr6:139373318 [GRCh38]
Chr6:139694455 [GRCh37]
Chr6:6q24.1		 likely benign
NM_006079.5(CITED2):c.138C>T (p.His46=) single nucleotide variant not provided [RCV000951267] Chr6:139373807 [GRCh38]
Chr6:139694944 [GRCh37]
Chr6:6q24.1		 likely benign
GRCh37/hg19 6q23.3-24.1(chr6:135936688-140660269)x1 copy number loss not provided [RCV001249247] Chr6:135936688..140660269 [GRCh37]
Chr6:6q23.3-24.1		 not provided
NM_006079.5(CITED2):c.582C>T (p.Gly194=) single nucleotide variant not provided [RCV000890236] Chr6:139373363 [GRCh38]
Chr6:139694500 [GRCh37]
Chr6:6q24.1		 benign|likely benign
NM_006079.5(CITED2):c.510G>C (p.Ser170=) single nucleotide variant not provided [RCV000956424] Chr6:139373435 [GRCh38]
Chr6:139694572 [GRCh37]
Chr6:6q24.1		 benign
NM_006079.5(CITED2):c.119AGC[3] (p.Gln43del) microsatellite Atrial septal defect 8 [RCV002471329] Chr6:139373815..139373817 [GRCh38]
Chr6:139694952..139694954 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.21C>A (p.Ala7=) single nucleotide variant not provided [RCV001617136] Chr6:139373924 [GRCh38]
Chr6:139695061 [GRCh37]
Chr6:6q24.1		 benign
NM_006079.5(CITED2):c.-8-97C>T single nucleotide variant not provided [RCV001616197] Chr6:139374049 [GRCh38]
Chr6:139695186 [GRCh37]
Chr6:6q24.1		 benign
NM_006079.5(CITED2):c.114CCA[1] (p.His39del) microsatellite Atrial septal defect 8 [RCV001335374]|not provided [RCV001729848]|not specified [RCV001729849] Chr6:139373826..139373828 [GRCh38]
Chr6:139694963..139694965 [GRCh37]
Chr6:6q24.1		 benign|likely benign|uncertain significance
NM_006079.5(CITED2):c.13A>G (p.Met5Val) single nucleotide variant not provided [RCV001356874] Chr6:139373932 [GRCh38]
Chr6:139695069 [GRCh37]
Chr6:6q24.1		 uncertain significance
GRCh37/hg19 6q23.2-24.1(chr6:133810210-140046615)x1 copy number loss not provided [RCV001537931] Chr6:133810210..140046615 [GRCh37]
Chr6:6q23.2-24.1		 pathogenic
NM_006079.5(CITED2):c.-24A>T single nucleotide variant not provided [RCV001692828] Chr6:139374428 [GRCh38]
Chr6:139695565 [GRCh37]
Chr6:6q24.1		 benign
NM_006079.5(CITED2):c.542G>C (p.Ser181Thr) single nucleotide variant not provided [RCV001528478] Chr6:139373403 [GRCh38]
Chr6:139694540 [GRCh37]
Chr6:6q24.1		 likely benign
Single allele deletion Autoinflammatory syndrome, familial, Behcet-like [RCV002247731] Chr6:134838331..142160056 [GRCh38]
Chr6:6q23.3-24.1		 pathogenic
NM_006079.5(CITED2):c.671A>G (p.Asp224Gly) single nucleotide variant not provided [RCV001771601] Chr6:139373274 [GRCh38]
Chr6:139694411 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.682_684del (p.Leu228del) deletion not provided [RCV001765451] Chr6:139373261..139373263 [GRCh38]
Chr6:139694398..139694400 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.524C>T (p.Thr175Ile) single nucleotide variant not specified [RCV001815098] Chr6:139373421 [GRCh38]
Chr6:139694558 [GRCh37]
Chr6:6q24.1		 uncertain significance
GRCh37/hg19 6q24.1(chr6:139093282-140660265) copy number gain not specified [RCV002053629] Chr6:139093282..140660265 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.574_579del (p.Ser192_Gly193del) deletion not specified [RCV002247987] Chr6:139373366..139373371 [GRCh38]
Chr6:139694503..139694508 [GRCh37]
Chr6:6q24.1		 benign
NM_006079.5(CITED2):c.19G>C (p.Ala7Pro) single nucleotide variant not provided [RCV003156443] Chr6:139373926 [GRCh38]
Chr6:139695063 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.80G>T (p.Arg27Leu) single nucleotide variant not provided [RCV002279148] Chr6:139373865 [GRCh38]
Chr6:139695002 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.296T>C (p.Met99Thr) single nucleotide variant Inborn genetic diseases [RCV002737027] Chr6:139373649 [GRCh38]
Chr6:139694786 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.166A>G (p.Ile56Val) single nucleotide variant Inborn genetic diseases [RCV002868143] Chr6:139373779 [GRCh38]
Chr6:139694916 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.686T>C (p.Met229Thr) single nucleotide variant Inborn genetic diseases [RCV002874914] Chr6:139373259 [GRCh38]
Chr6:139694396 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.193G>T (p.Ala65Ser) single nucleotide variant Inborn genetic diseases [RCV002934868] Chr6:139373752 [GRCh38]
Chr6:139694889 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.694G>A (p.Val232Met) single nucleotide variant not provided [RCV003144991] Chr6:139373251 [GRCh38]
Chr6:139694388 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.421G>A (p.Ala141Thr) single nucleotide variant not provided [RCV003144990] Chr6:139373524 [GRCh38]
Chr6:139694661 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.562G>A (p.Gly188Ser) single nucleotide variant Inborn genetic diseases [RCV003207339] Chr6:139373383 [GRCh38]
Chr6:139694520 [GRCh37]
Chr6:6q24.1		 uncertain significance
NM_006079.5(CITED2):c.63C>A (p.His21Gln) single nucleotide variant Inborn genetic diseases [RCV003192665] Chr6:139373882 [GRCh38]
Chr6:139695019 [GRCh37]
Chr6:6q24.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1251
Count of miRNA genes:340
Interacting mature miRNAs:380
Transcripts:ENST00000367651, ENST00000536159, ENST00000537332
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH12860  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376139,693,546 - 139,693,687UniSTSGRCh37
Build 366139,735,239 - 139,735,380RGDNCBI36
Celera6140,433,609 - 140,433,750RGD
Cytogenetic Map6q23.3UniSTS
HuRef6137,254,772 - 137,254,913UniSTS
GeneMap99-GB4 RH Map6562.39UniSTS
NCBI RH Map61561.4UniSTS
CITED2_2297  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376139,693,280 - 139,694,023UniSTSGRCh37
Build 366139,734,973 - 139,735,716RGDNCBI36
Celera6140,433,343 - 140,434,086RGD
HuRef6137,254,506 - 137,255,249UniSTS
D6S2114  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376139,693,877 - 139,694,009UniSTSGRCh37
Build 366139,735,570 - 139,735,702RGDNCBI36
Celera6140,433,940 - 140,434,072RGD
Cytogenetic Map6q23.3UniSTS
HuRef6137,255,103 - 137,255,235UniSTS
Stanford-G3 RH Map65759.0UniSTS
GeneMap99-G3 RH Map66062.0UniSTS
Meis2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376139,694,627 - 139,694,812UniSTSGRCh37
Celera6140,434,690 - 140,434,875UniSTS
HuRef6137,255,855 - 137,256,040UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 2 6 1 1 1 3 3 5 8
Medium 2412 2783 1662 607 1813 449 4278 2025 2284 412 1432 1594 170 1204 2719 4
Low 18 201 55 14 132 14 74 165 1422 6 11 6 1 69
Below cutoff 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_016169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001168388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001168389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA400897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AA767624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF109161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF129290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI087283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL592429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG900380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI763038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM763150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM851650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF126189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM015589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U65093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000367651   ⟹   ENSP00000356623
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6139,371,807 - 139,374,648 (-)Ensembl
RefSeq Acc Id: ENST00000536159   ⟹   ENSP00000442831
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6139,372,255 - 139,374,362 (-)Ensembl
RefSeq Acc Id: ENST00000537332   ⟹   ENSP00000444198
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6139,372,255 - 139,374,213 (-)Ensembl
RefSeq Acc Id: ENST00000618718   ⟹   ENSP00000479918
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl6139,373,074 - 139,374,605 (-)Ensembl
RefSeq Acc Id: NM_001168388   ⟹   NP_001161860
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386139,371,807 - 139,374,362 (-)NCBI
GRCh376139,693,392 - 139,695,787 (-)NCBI
HuRef6137,254,618 - 137,257,015 (-)NCBI
CHM1_16139,956,432 - 139,958,539 (-)NCBI
T2T-CHM13v2.06140,555,711 - 140,558,263 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001168389   ⟹   NP_001161861
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386139,371,807 - 139,374,213 (-)NCBI
GRCh376139,693,392 - 139,695,787 (-)NCBI
HuRef6137,254,618 - 137,257,015 (-)NCBI
CHM1_16139,956,432 - 139,958,390 (-)NCBI
T2T-CHM13v2.06140,555,711 - 140,558,114 (-)NCBI
Sequence:
RefSeq Acc Id: NM_006079   ⟹   NP_006070
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386139,371,807 - 139,374,648 (-)NCBI
GRCh376139,693,392 - 139,695,787 (-)NCBI
Build 366139,735,089 - 139,737,478 (-)NCBI Archive
HuRef6137,254,618 - 137,257,015 (-)NCBI
CHM1_16139,956,432 - 139,958,827 (-)NCBI
T2T-CHM13v2.06140,555,711 - 140,558,549 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_006070   ⟸   NM_006079
- Peptide Label: isoform 1
- UniProtKB: Q5VTF4 (UniProtKB/Swiss-Prot),   Q99967 (UniProtKB/Swiss-Prot),   D9ZGF1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001161860   ⟸   NM_001168388
- Peptide Label: isoform 1
- UniProtKB: Q5VTF4 (UniProtKB/Swiss-Prot),   Q99967 (UniProtKB/Swiss-Prot),   D9ZGF1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001161861   ⟸   NM_001168389
- Peptide Label: isoform 2
- UniProtKB: Q99967 (UniProtKB/Swiss-Prot),   A0A0A0MTM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000442831   ⟸   ENST00000536159
RefSeq Acc Id: ENSP00000444198   ⟸   ENST00000537332
RefSeq Acc Id: ENSP00000356623   ⟸   ENST00000367651
RefSeq Acc Id: ENSP00000479918   ⟸   ENST00000618718

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99967-F1-model_v2 AlphaFold Q99967 1-270 view protein structure

Promoters
RGD ID:7209287
Promoter ID:EPDNEW_H10389
Type:initiation region
Name:CITED2_1
Description:Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminaldomain 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386139,374,648 - 139,374,708EPDNEW
RGD ID:6803897
Promoter ID:HG_KWN:55216
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000392312,   NM_001168388,   NM_001168389,   OTTHUMT00000042463,   UC010KHB.1
Position:
Human AssemblyChrPosition (strand)Source
Build 366139,736,001 - 139,738,412 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1987 AgrOrtholog
COSMIC CITED2 COSMIC
Ensembl Genes ENSG00000164442 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000356623 ENTREZGENE
  ENSP00000356623.2 UniProtKB/Swiss-Prot
  ENSP00000442831 ENTREZGENE
  ENSP00000442831.1 UniProtKB/Swiss-Prot
  ENSP00000444198 ENTREZGENE
  ENSP00000444198.2 UniProtKB/TrEMBL
  ENSP00000479918.1 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000367651 ENTREZGENE
  ENST00000367651.4 UniProtKB/Swiss-Prot
  ENST00000536159 ENTREZGENE
  ENST00000536159.2 UniProtKB/Swiss-Prot
  ENST00000537332 ENTREZGENE
  ENST00000537332.2 UniProtKB/TrEMBL
  ENST00000618718.1 UniProtKB/Swiss-Prot
Gene3D-CATH 6.10.140.2200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000164442 GTEx
HGNC ID HGNC:1987 ENTREZGENE
Human Proteome Map CITED2 Human Proteome Map
InterPro CITED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:10370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 10370 ENTREZGENE
OMIM 602937 OMIM
PANTHER CBP/P300-INTERACTING TRANSACTIVATOR 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR17045 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CITED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26524 PharmGKB
UniProt A0A0A0MTM3 ENTREZGENE, UniProtKB/TrEMBL
  CITE2_HUMAN UniProtKB/Swiss-Prot
  D9ZGF1 ENTREZGENE, UniProtKB/TrEMBL
  Q5VTF4 ENTREZGENE
  Q99967 ENTREZGENE
UniProt Secondary O95426 UniProtKB/Swiss-Prot
  Q5VTF4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-29 CITED2  Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2    Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2  Symbol and/or name change 5135510 APPROVED
2015-11-10 CITED2  Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2    Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2  Symbol and/or name change 5135510 APPROVED