Hyal2 (hyaluronoglucosaminidase 2) - Rat Genome Database

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Gene: Hyal2 (hyaluronoglucosaminidase 2) Mus musculus
Analyze
Symbol: Hyal2
Name: hyaluronoglucosaminidase 2
RGD ID: 733699
MGI Page MGI
Description: Enables several functions, including hyalurononglucosaminidase activity; transforming growth factor beta binding activity; and virus receptor activity. Contributes to transcription coactivator activity. Involved in several processes, including cellular response to transforming growth factor beta stimulus; hyaluronan catabolic process; and positive regulation of protein import into nucleus. Acts upstream of or within several processes, including hematopoietic progenitor cell differentiation; multicellular organismal-level iron ion homeostasis; and positive regulation of extrinsic apoptotic signaling pathway. Located in cell surface; membrane raft; and plasma membrane. Part of RNA polymerase II transcription regulator complex. Colocalizes with external side of plasma membrane. Is expressed in several structures, including alimentary system; heart; lateral plate mesoderm; respiratory system; and submandibular gland primordium. Orthologous to human HYAL2 (hyaluronidase 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI256841; AU020858; AW555733; hyal-2; hyaluronidase 2; hyaluronidase-2; hyaluronoglucosaminidase-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,445,096 - 107,449,975 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9107,445,144 - 107,449,978 (+)EnsemblGRCm39 Ensembl
GRCm389107,567,873 - 107,572,778 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,567,945 - 107,572,779 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,471,494 - 107,475,109 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369107,427,264 - 107,430,879 (+)NCBIMGSCv36mm8
Celera9107,177,912 - 107,181,527 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map958.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
carbohydrate metabolic process  (IEA)
cartilage development  (ISS)
cellular response to fibroblast growth factor stimulus  (ISO,ISS)
cellular response to interleukin-1  (ISO,ISS)
cellular response to transforming growth factor beta stimulus  (IDA,ISO)
cellular response to tumor necrosis factor  (IEA)
cellular response to UV-B  (ISO,ISS)
defense response to virus  (IDA)
fusion of virus membrane with host plasma membrane  (ISO,ISS)
glycosaminoglycan catabolic process  (ISO,ISS)
hematopoietic progenitor cell differentiation  (IMP)
hyaluronan catabolic process  (IBA,IMP,ISO,ISS)
kidney development  (ISO)
monocyte activation  (ISO,ISS)
multicellular organismal-level iron ion homeostasis  (IMP)
negative regulation of cell growth  (ISO,ISS)
negative regulation of fibroblast migration  (ISO,ISS)
negative regulation of MAP kinase activity  (ISO,ISS)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO,ISS)
negative regulation of protein tyrosine kinase activity  (ISO,ISS)
positive regulation of extrinsic apoptotic signaling pathway  (IDA,IMP)
positive regulation of inflammatory response  (ISO,ISS)
positive regulation of interleukin-6 production  (ISO,ISS)
positive regulation of interleukin-8 production  (ISO,ISS)
positive regulation of protein import into nucleus  (IDA)
positive regulation of transcription by RNA polymerase II  (IDA)
positive regulation of urine volume  (ISS)
renal water absorption  (ISS)
response to antibiotic  (IEA)
response to reactive oxygen species  (ISO,ISS)
response to virus  (IDA,ISO)
skeletal system morphogenesis  (IMP)
symbiont entry into host cell  (ISO,ISS)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Synthesis and fragmentation of hyaluronan in renal ischaemia. Decleves AE, etal., Nephrol Dial Transplant. 2012 Oct;27(10):3771-81. doi: 10.1093/ndt/gfs098. Epub 2012 Apr 23.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. The enzymatic degradation of hyaluronan is associated with disease progression in experimental pulmonary hypertension. Ormiston ML, etal., Am J Physiol Lung Cell Mol Physiol. 2010 Feb;298(2):L148-57. doi: 10.1152/ajplung.00097.2009. Epub 2009 Nov 13.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3. Shuttleworth TL, etal., J Biol Chem 2002 Jun 21;277(25):23008-18. Epub 2002 Apr 02.
Additional References at PubMed
PMID:7671812   PMID:9790770   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11296287   PMID:11731268   PMID:11960552   PMID:12477932   PMID:12584308  
PMID:14610273   PMID:14681479   PMID:15090545   PMID:16141072   PMID:16141073   PMID:16191204   PMID:18267097   PMID:18653706   PMID:18772348   PMID:18799693   PMID:19366691   PMID:19443707  
PMID:20487527   PMID:21084671   PMID:21267068   PMID:21740893   PMID:21873635   PMID:23172227   PMID:25232017   PMID:25468725   PMID:25715119   PMID:25934767   PMID:26887442   PMID:26901790  
PMID:27398974   PMID:28081210   PMID:28196902   PMID:28765635   PMID:29743679   PMID:31262781   PMID:31434798   PMID:38490466  


Genomics

Comparative Map Data
Hyal2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,445,096 - 107,449,975 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9107,445,144 - 107,449,978 (+)EnsemblGRCm39 Ensembl
GRCm389107,567,873 - 107,572,778 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9107,567,945 - 107,572,779 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,471,494 - 107,475,109 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369107,427,264 - 107,430,879 (+)NCBIMGSCv36mm8
Celera9107,177,912 - 107,181,527 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map958.12NCBI
HYAL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38350,317,808 - 50,322,745 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl350,317,790 - 50,322,782 (-)EnsemblGRCh38hg38GRCh38
GRCh37350,355,239 - 50,360,176 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36350,330,244 - 50,335,146 (-)NCBINCBI36Build 36hg18NCBI36
Build 34350,330,243 - 50,333,903NCBI
Celera350,328,056 - 50,333,116 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef350,410,935 - 50,415,994 (-)NCBIHuRef
CHM1_1350,307,488 - 50,312,547 (-)NCBICHM1_1
T2T-CHM13v2.0350,347,534 - 50,352,469 (-)NCBIT2T-CHM13v2.0
Hyal2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88117,121,802 - 117,125,494 (+)NCBIGRCr8
mRatBN7.28108,241,895 - 108,246,853 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8108,243,133 - 108,246,850 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8113,870,193 - 113,873,885 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08112,069,349 - 112,073,041 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08109,912,130 - 109,915,822 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08116,324,062 - 116,328,978 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,324,040 - 116,328,978 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08115,680,309 - 115,685,238 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48112,817,001 - 112,820,693 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18112,836,484 - 112,840,147 (+)NCBI
Celera8107,549,728 - 107,586,609 (+)NCBICelera
Cytogenetic Map8q32NCBI
Hyal2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555322,120,781 - 2,123,726 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555322,120,781 - 2,125,083 (-)NCBIChiLan1.0ChiLan1.0
HYAL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2250,298,400 - 50,303,389 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1350,303,163 - 50,308,164 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0350,243,926 - 50,248,972 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1351,479,020 - 51,484,638 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl351,479,020 - 51,482,551 (-)Ensemblpanpan1.1panPan2
HYAL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,029,426 - 39,034,451 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,031,735 - 39,034,130 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2038,950,366 - 38,955,492 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02039,385,361 - 39,390,488 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2039,385,565 - 39,396,473 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12038,753,188 - 38,758,313 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02039,156,748 - 39,161,868 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02039,436,765 - 39,441,893 (+)NCBIUU_Cfam_GSD_1.0
Hyal2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560265,084,685 - 65,090,478 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365291,845,763 - 1,851,252 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365291,845,445 - 1,851,106 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HYAL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,805,227 - 32,815,333 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,805,220 - 32,813,684 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,983,753 - 35,988,635 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap13q21NCBI
HYAL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,704,422 - 11,710,013 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2211,703,790 - 11,709,454 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041155,277,024 - 155,282,088 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hyal2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247304,169,742 - 4,175,242 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247304,170,045 - 4,175,264 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hyal2
143 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:157
Count of miRNA genes:136
Interacting mature miRNAs:149
Transcripts:ENSMUST00000010191
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9101829255124359700Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103118511124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103118511124359700Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103118511124359700Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9100889929124359700Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9101829255124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse

Markers in Region
RH136104  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,572,427 - 107,572,607UniSTSGRCm38
MGSCv379107,474,758 - 107,474,938UniSTSGRCm37
Celera9107,181,176 - 107,181,356UniSTS
Cytogenetic Map9F1UniSTS
cM Map960.0UniSTS
RH136576  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,572,512 - 107,572,724UniSTSGRCm38
MGSCv379107,474,843 - 107,475,055UniSTSGRCm37
Celera9107,181,261 - 107,181,473UniSTS
Cytogenetic Map9F1UniSTS
cM Map960.0UniSTS
AW555733  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,572,592 - 107,572,690UniSTSGRCm38
MGSCv379107,474,923 - 107,475,021UniSTSGRCm37
Celera9107,181,341 - 107,181,439UniSTS
Cytogenetic Map9F1UniSTS
cM Map960.0UniSTS
Whitehead/MRC_RH91107.66UniSTS
UniSTS:236246  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,572,317 - 107,572,472UniSTSGRCm38
MGSCv379107,474,648 - 107,474,803UniSTSGRCm37
Celera9107,181,066 - 107,181,221UniSTS
Cytogenetic Map9F1UniSTS
cM Map960.0UniSTS
Hyal2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,570,944 - 107,571,506UniSTSGRCm38
MGSCv379107,473,889 - 107,474,700UniSTSGRCm37
MGSCv379107,473,218 - 107,474,436UniSTSGRCm37
MGSCv379107,473,378 - 107,473,855UniSTSGRCm37
Celera9107,179,693 - 107,180,255UniSTS
Cytogenetic Map9F1UniSTS
cM Map960.0UniSTS
cM Map960.0UniSTS
Hyal2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,570,887 - 107,572,105UniSTSGRCm38
MGSCv379107,473,218 - 107,474,436UniSTSGRCm37
Celera9107,179,636 - 107,180,854UniSTS
Cytogenetic Map9F1UniSTS
Hyal2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,571,047 - 107,571,524UniSTSGRCm38
MGSCv379107,473,378 - 107,473,855UniSTSGRCm37
Celera9107,179,796 - 107,180,273UniSTS
Cytogenetic Map9F1UniSTS
Hyal2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm389107,571,558 - 107,572,369UniSTSGRCm38
MGSCv379107,473,889 - 107,474,700UniSTSGRCm37
Celera9107,180,307 - 107,181,118UniSTS
Cytogenetic Map9F1UniSTS
cM Map960.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001409671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001409672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006511643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036154613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF302843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF302844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF422177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF535140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ000060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK087358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL672219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC060047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000010191   ⟹   ENSMUSP00000010191
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,446,316 - 107,449,975 (+)Ensembl
GRCm38.p6 Ensembl9107,569,117 - 107,572,776 (+)Ensembl
Ensembl Acc Id: ENSMUST00000192887   ⟹   ENSMUSP00000142207
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,445,144 - 107,447,593 (+)Ensembl
GRCm38.p6 Ensembl9107,567,945 - 107,570,394 (+)Ensembl
Ensembl Acc Id: ENSMUST00000193747   ⟹   ENSMUSP00000142141
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,446,340 - 107,449,162 (+)Ensembl
GRCm38.p6 Ensembl9107,569,141 - 107,571,963 (+)Ensembl
Ensembl Acc Id: ENSMUST00000194794   ⟹   ENSMUSP00000142019
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,446,594 - 107,447,811 (+)Ensembl
GRCm38.p6 Ensembl9107,569,395 - 107,570,612 (+)Ensembl
Ensembl Acc Id: ENSMUST00000195667
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,448,409 - 107,449,402 (+)Ensembl
GRCm38.p6 Ensembl9107,571,210 - 107,572,203 (+)Ensembl
Ensembl Acc Id: ENSMUST00000195681   ⟹   ENSMUSP00000141820
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,447,004 - 107,449,971 (+)Ensembl
GRCm38.p6 Ensembl9107,569,805 - 107,572,772 (+)Ensembl
Ensembl Acc Id: ENSMUST00000195752   ⟹   ENSMUSP00000141280
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl9107,445,144 - 107,449,978 (+)Ensembl
GRCm38.p6 Ensembl9107,567,945 - 107,572,779 (+)Ensembl
RefSeq Acc Id: NM_001409671   ⟹   NP_001396600
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,445,118 - 107,449,970 (+)NCBI
RefSeq Acc Id: NM_001409672   ⟹   NP_001396601
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,446,598 - 107,449,970 (+)NCBI
RefSeq Acc Id: NM_010489   ⟹   NP_034619
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,446,325 - 107,449,970 (+)NCBI
GRCm389107,569,163 - 107,572,778 (+)NCBI
MGSCv379107,471,494 - 107,475,109 (+)RGD
Celera9107,177,912 - 107,181,527 (+)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006511643   ⟹   XP_006511706
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,445,097 - 107,449,975 (+)NCBI
GRCm389107,567,897 - 107,572,776 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036154613   ⟹   XP_036010506
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399107,445,096 - 107,449,975 (+)NCBI
Sequence:
RefSeq Acc Id: NP_034619   ⟸   NM_010489
- Peptide Label: precursor
- UniProtKB: Q99MS9 (UniProtKB/Swiss-Prot),   O35631 (UniProtKB/Swiss-Prot),   Q99MT0 (UniProtKB/Swiss-Prot),   O35632 (UniProtKB/Swiss-Prot),   Q3UZE4 (UniProtKB/TrEMBL),   Q542F2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006511706   ⟸   XM_006511643
- Peptide Label: isoform X1
- UniProtKB: Q99MS9 (UniProtKB/Swiss-Prot),   O35631 (UniProtKB/Swiss-Prot),   Q99MT0 (UniProtKB/Swiss-Prot),   O35632 (UniProtKB/Swiss-Prot),   Q3UZE4 (UniProtKB/TrEMBL),   Q542F2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000142141   ⟸   ENSMUST00000193747
Ensembl Acc Id: ENSMUSP00000142207   ⟸   ENSMUST00000192887
Ensembl Acc Id: ENSMUSP00000010191   ⟸   ENSMUST00000010191
Ensembl Acc Id: ENSMUSP00000141820   ⟸   ENSMUST00000195681
Ensembl Acc Id: ENSMUSP00000141280   ⟸   ENSMUST00000195752
Ensembl Acc Id: ENSMUSP00000142019   ⟸   ENSMUST00000194794
RefSeq Acc Id: XP_036010506   ⟸   XM_036154613
- Peptide Label: isoform X1
- UniProtKB: Q99MS9 (UniProtKB/Swiss-Prot),   O35632 (UniProtKB/Swiss-Prot),   O35631 (UniProtKB/Swiss-Prot),   Q99MT0 (UniProtKB/Swiss-Prot),   Q3UZE4 (UniProtKB/TrEMBL),   Q542F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001396600   ⟸   NM_001409671
- Peptide Label: precursor
- UniProtKB: Q99MS9 (UniProtKB/Swiss-Prot),   O35632 (UniProtKB/Swiss-Prot),   O35631 (UniProtKB/Swiss-Prot),   Q99MT0 (UniProtKB/Swiss-Prot),   Q3UZE4 (UniProtKB/TrEMBL),   Q542F2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001396601   ⟸   NM_001409672
- Peptide Label: precursor
- UniProtKB: Q99MS9 (UniProtKB/Swiss-Prot),   O35632 (UniProtKB/Swiss-Prot),   O35631 (UniProtKB/Swiss-Prot),   Q99MT0 (UniProtKB/Swiss-Prot),   Q3UZE4 (UniProtKB/TrEMBL),   Q542F2 (UniProtKB/TrEMBL)
Protein Domains
EGF-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35632-F1-model_v2 AlphaFold O35632 1-473 view protein structure

Promoters
RGD ID:6844671
Promoter ID:MM_KWN:58724
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   ES_Cell,   Kidney,   MEF_B4
Transcripts:ENSMUST00000010191,   UC009RLT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369107,470,461 - 107,471,562 (+)MPROMDB
RGD ID:8670802
Promoter ID:EPDNEW_M13431
Type:initiation region
Name:Hyal2_1
Description:Mus musculus hyaluronoglucosaminidase 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389107,569,126 - 107,569,186EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1196334 AgrOrtholog
Ensembl Genes ENSMUSG00000010047 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000010191 ENTREZGENE
  ENSMUST00000010191.13 UniProtKB/Swiss-Prot
  ENSMUST00000192887.6 UniProtKB/TrEMBL
  ENSMUST00000193747.2 UniProtKB/TrEMBL
  ENSMUST00000194794.2 UniProtKB/TrEMBL
  ENSMUST00000195681.2 UniProtKB/TrEMBL
  ENSMUST00000195752 ENTREZGENE
  ENSMUST00000195752.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.20.20.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hyaluronidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15587 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1196334 ENTREZGENE
NCBI Gene 15587 ENTREZGENE
PANTHER HYALURONIDASE-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glyco_hydro_56 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hyal2 PhenoGen
PIRSF Hyaluronidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS GLHYDRLASE56 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A6YX37_MOUSE UniProtKB/TrEMBL
  A0A0A6YXJ6_MOUSE UniProtKB/TrEMBL
  A0A0A6YXZ3_MOUSE UniProtKB/TrEMBL
  HYAL2_MOUSE UniProtKB/Swiss-Prot
  O35631 ENTREZGENE
  O35632 ENTREZGENE
  Q3UZE4 ENTREZGENE, UniProtKB/TrEMBL
  Q542F2 ENTREZGENE, UniProtKB/TrEMBL
  Q8C309_MOUSE UniProtKB/TrEMBL
  Q99MS9 ENTREZGENE
  Q99MT0 ENTREZGENE
UniProt Secondary O35631 UniProtKB/Swiss-Prot
  Q99MS9 UniProtKB/Swiss-Prot
  Q99MT0 UniProtKB/Swiss-Prot