Rxrg (retinoid X receptor gamma) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Rxrg (retinoid X receptor gamma) Mus musculus
Analyze
Symbol: Rxrg
Name: retinoid X receptor gamma
RGD ID: 733409
MGI Page MGI
Description: Enables nuclear receptor activity and sequence-specific DNA binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II and retinoic acid receptor signaling pathway. Predicted to be located in cytoplasm and nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; musculature; and sensory organ. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human RXRG (retinoid X receptor gamma).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Nr2; Nr2b3; nuclear receptor subfamily 2 group B member 3; retinoic acid receptor RXR-gamma
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,425,902 - 167,467,191 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,425,953 - 167,467,192 (+)EnsemblGRCm39 Ensembl
GRCm381167,598,362 - 167,639,623 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,598,384 - 167,639,623 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,528,493 - 169,569,754 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,435,059 - 169,476,298 (+)NCBIMGSCv36mm8
Celera1170,022,008 - 170,069,461 (+)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map174.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
2-hydroxyphytanic acid  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-phenoxybenzoic acid  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
9-cis-retinoic acid  (EXP,ISO)
acrylamide  (ISO)
aldrin  (EXP)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP,ISO)
amiodarone  (EXP)
amitrole  (ISO)
ammonium chloride  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bexarotene  (EXP,ISO)
bezafibrate  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium sulfate  (EXP,ISO)
carbon nanotube  (EXP)
cefaloridine  (ISO)
CGP 52608  (ISO)
chlorpromazine  (EXP)
clofibrate  (ISO)
clozapine  (ISO)
Cuprizon  (ISO)
D-gluconic acid  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP)
Di-n-hexyl phthalate  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
diheptyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
Dimethyl phthalate  (ISO)
dimethyl sulfoxide  (EXP)
dioxygen  (ISO)
dipentyl phthalate  (ISO)
dipropyl phthalate  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
fentin hydroxide  (ISO)
fenvalerate  (ISO)
fulvestrant  (ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (ISO)
glafenine  (ISO)
griseofulvin  (EXP)
haloperidol  (EXP,ISO)
hydralazine  (ISO)
indometacin  (ISO)
ketamine  (ISO)
ketoconazole  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (EXP,ISO)
mercury dichloride  (ISO)
methapyrilene  (ISO)
methotrexate  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
nimesulide  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phthalic acid  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sodium arsenite  (EXP)
sulforaphane  (EXP)
sunitinib  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetracycline  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
tributylstannane  (EXP,ISO)
trichloroethene  (EXP)
triclosan  (ISO)
trimellitic anhydride  (EXP)
triticonazole  (ISO)
valproic acid  (ISO)
vinyl carbamate  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. WNT10A/ß-catenin pathway in tumorigenesis of papillary thyroid carcinoma. Dong T, etal., Oncol Rep. 2017 Aug;38(2):1287-1294. doi: 10.3892/or.2017.5777. Epub 2017 Jul 3.
2. International Union of Pharmacology. LXIII. Retinoid X receptors. Germain P, etal., Pharmacol Rev. 2006 Dec;58(4):760-72.
3. Epigenetic inactivation of retinoid X receptor genes in non-small cell lung cancer and the relationship with clinicopathologic features. Lee SM, etal., Cancer Genet Cytogenet. 2010 Feb;197(1):39-45. doi: 10.1016/j.cancergencyto.2009.10.008.
4. Vitamin A regulation of gene expression: molecular mechanism of a prototype gene. McGrane MM J Nutr Biochem. 2007 Aug;18(8):497-508. Epub 2007 Feb 22.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1301170   PMID:1310259   PMID:1312497   PMID:1358808   PMID:7708713   PMID:7823919   PMID:7831303   PMID:7947324   PMID:7980510   PMID:7988794   PMID:8090775   PMID:8199055  
PMID:8299717   PMID:8391126   PMID:8563020   PMID:8628649   PMID:8650181   PMID:8799145   PMID:8801169   PMID:8801176   PMID:8801178   PMID:8827514   PMID:8901052   PMID:9022057  
PMID:9050783   PMID:9075714   PMID:9153406   PMID:9250876   PMID:9428411   PMID:9452386   PMID:9464546   PMID:9548551   PMID:9682978   PMID:9804293   PMID:9806918   PMID:9883728  
PMID:10079186   PMID:10094571   PMID:10336693   PMID:10349636   PMID:10406480   PMID:10444330   PMID:10449983   PMID:10452855   PMID:10464288   PMID:10490294   PMID:10547923   PMID:10556054  
PMID:10604193   PMID:10693804   PMID:10753524   PMID:10842103   PMID:10880050   PMID:11042159   PMID:11053444   PMID:11076861   PMID:11217851   PMID:11328745   PMID:11331379   PMID:11493527  
PMID:11713233   PMID:11795391   PMID:12114515   PMID:12360493   PMID:12466851   PMID:12477932   PMID:12819125   PMID:12824162   PMID:12941622   PMID:12953790   PMID:14681479   PMID:15142957  
PMID:15163632   PMID:15489334   PMID:15589691   PMID:15618518   PMID:15897255   PMID:15939381   PMID:16038893   PMID:16043864   PMID:16110338   PMID:16141072   PMID:16141073   PMID:16306084  
PMID:16428452   PMID:16602821   PMID:16690048   PMID:16971476   PMID:17124491   PMID:17195188   PMID:17270348   PMID:17609113   PMID:18171945   PMID:18202130   PMID:18287559   PMID:18367606  
PMID:18393306   PMID:18443282   PMID:18561907   PMID:19014374   PMID:19030180   PMID:19386638   PMID:19448158   PMID:19605690   PMID:19686701   PMID:19737349   PMID:19805139   PMID:19828801  
PMID:20144606   PMID:20211142   PMID:20392955   PMID:20557428   PMID:20620876   PMID:20932939   PMID:21087508   PMID:21131950   PMID:21267068   PMID:21334601   PMID:21452241   PMID:21525287  
PMID:21873635   PMID:21940995   PMID:22323600   PMID:22988430   PMID:23112163   PMID:23375831   PMID:23884928   PMID:24443808   PMID:24453340   PMID:24523460   PMID:24952961   PMID:25100656  
PMID:25179941   PMID:25209997   PMID:25228773   PMID:25501893   PMID:25556712   PMID:25577283   PMID:25637539   PMID:25794677   PMID:26030625   PMID:26190982   PMID:26427057   PMID:26658258  
PMID:26965927   PMID:27405468   PMID:27445154   PMID:28288836   PMID:28291835   PMID:28346476   PMID:29031500   PMID:29093497   PMID:29509905   PMID:29922981   PMID:30093671   PMID:30635555  
PMID:30647151   PMID:30783126   PMID:31163126   PMID:31260032   PMID:32071204   PMID:32325033   PMID:32878923   PMID:32986815   PMID:33692389   PMID:33712461   PMID:33723039   PMID:34292881  
PMID:34321664   PMID:34599305   PMID:35156680   PMID:35486208   PMID:36064547   PMID:36537580   PMID:36924502   PMID:37048108   PMID:37073980   PMID:37225978   PMID:37259952   PMID:37524711  


Genomics

Comparative Map Data
Rxrg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,425,902 - 167,467,191 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,425,953 - 167,467,192 (+)EnsemblGRCm39 Ensembl
GRCm381167,598,362 - 167,639,623 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,598,384 - 167,639,623 (+)EnsemblGRCm38mm10GRCm38
MGSCv371169,528,493 - 169,569,754 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,435,059 - 169,476,298 (+)NCBIMGSCv36mm8
Celera1170,022,008 - 170,069,461 (+)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map174.99NCBI
RXRG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,400,922 - 165,445,126 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,400,922 - 165,445,355 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,370,159 - 165,414,363 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,636,974 - 163,681,054 (-)NCBINCBI36Build 36hg18NCBI36
Build 341162,102,008 - 162,146,088NCBI
Celera1138,475,332 - 138,519,756 (-)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1136,616,922 - 136,661,341 (-)NCBIHuRef
CHM1_11166,792,871 - 166,837,301 (-)NCBICHM1_1
T2T-CHM13v2.01164,747,271 - 164,791,474 (-)NCBIT2T-CHM13v2.0
Rxrg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81382,276,330 - 82,318,097 (+)NCBIGRCr8
mRatBN7.21379,743,430 - 79,785,173 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,743,563 - 79,785,167 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,373,401 - 82,414,881 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,680,439 - 83,722,040 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,918,510 - 80,960,010 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,818,473 - 85,868,555 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,818,427 - 85,868,552 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01390,460,380 - 90,511,048 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41383,256,823 - 83,298,724 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11383,287,103 - 83,307,114 (+)NCBI
Celera1379,448,171 - 79,489,515 (+)NCBICelera
Cytogenetic Map13q24NCBI
Rxrg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546211,238,794 - 11,281,956 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546211,238,963 - 11,281,905 (+)NCBIChiLan1.0ChiLan1.0
RXRG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2184,320,687 - 84,365,083 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1183,989,216 - 84,033,594 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01140,832,717 - 140,877,046 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11144,623,133 - 144,667,503 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,623,133 - 144,723,494 (-)Ensemblpanpan1.1panPan2
RXRG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13817,867,123 - 17,912,328 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3817,867,182 - 17,920,085 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3817,922,970 - 17,968,200 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03817,947,065 - 17,992,337 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3817,947,141 - 18,000,604 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13817,919,625 - 17,964,835 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03818,271,342 - 18,316,575 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03818,565,728 - 18,610,954 (+)NCBIUU_Cfam_GSD_1.0
Rxrg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344101,933,905 - 101,979,926 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648119,789,641 - 19,826,698 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648119,789,753 - 19,826,665 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RXRG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl485,308,508 - 85,357,137 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1485,158,313 - 85,357,116 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2492,982,235 - 93,063,524 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RXRG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12563,444,128 - 63,490,594 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2563,443,944 - 63,490,635 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605565,204,356 - 65,250,988 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rxrg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248263,736,290 - 3,780,338 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248263,723,056 - 3,969,597 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:895
Count of miRNA genes:293
Interacting mature miRNAs:318
Transcripts:ENSMUST00000015987, ENSMUST00000111380, ENSMUST00000111384, ENSMUST00000111386
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301523Ccrs1_mcorpus callosum hemisphere surface size 1 (mouse)Not determined1139602037173602216Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160097157194097157Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
12790984Pcho7_mplasma cholesterol 7 (mouse)1147219390181219390Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160097157194097157Mouse
1300740Tne1_mtotal number errors (mouse)Not determined1139602037173602216Mouse
12790996Aath2_maortic arch atherosclerosis 2 (mouse)1145077630179077630Mouse
12791001Aath6_maortic arch atherosclerosis 6 (mouse)1147219390181219390Mouse
1300745Gvhd1_mgraft-versus-host disease 1 (mouse)Not determined1157456299191456436Mouse
10412162Nobq3_mNew Zealand obese QTL 3 (mouse)Not determined1103933405191225397Mouse
4141346Skmw12_mskeletal muscle weight 12 (mouse)Not determined150756737184756922Mouse
1357618Splq5_mspleen weight QTL 5 (mouse)Not determined1150193673188359312Mouse
1301301Sle1_msystemic lupus erythmatosus susceptibility 1 (mouse)Not determined1152038741186038913Mouse
1301818Ap1q_malcohol preference 1 QTL (mouse)Not determined1146908199167586222Mouse
12904936Edlmmq1_mextensor digitorum longus muscle mass QTL 1 (mouse)1155002940189002940Mouse
1301565Mnotch_mmodifier of Notch (mouse)Not determined1157456299191456436Mouse
1301309Emo1_memotionality 1 (mouse)Not determined1162977097185994196Mouse
1301025Lbw7_mlupus NZB x NZW 7 (mouse)Not determined1152038741186038913Mouse
12904944Tammq1_mtibialis anterior muscle mass QTL 1 (mouse)1155002940189002940Mouse
1357602Vtbt2_mvertebral trabecular bone trait 2 (mouse)Not determined1139602037173602216Mouse
12904957Gmmq1_mgastrocnemius muscle mass QTL 1 (mouse)1155002940189002940Mouse
1300777Chol10_mcholesterol 10 (mouse)Not determined9147875502181875616Mouse
1302098Eila1_methanol induced locomotor activity 1 (mouse)Not determined1112008822175468938Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160112768194112883Mouse
1300571Opfa_mopen field activity (mouse)Not determined1144531347178531592Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1165873675195154279Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162145207194111528Mouse
4141165Bglu3_mblood glucose level 3 (mouse)Not determined155831765189831892Mouse
1357889Lprq3_mlipoprotein QTL 3 (mouse)Not determined1152038741186038913Mouse
4141160Cq1_mcholesterol QTL 1 (mouse)Not determined1139452188173452308Mouse
4142182Shali5_msurvival time to hyperoxic acute lung injury 5 (mouse)Not determined155582237185994196Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158468817192468938Mouse
1301619Cafq1_mcaffeine metabolism QTL 1 (mouse)Not determined1155716221189716369Mouse
4141149Hbnr4_mHeligmosomoides bakeri nematode resistance 4 (mouse)Not determined147125258188983224Mouse
10043899Hdlq99_mHDL QTL 99 (mouse)Not determined1147875502181875616Mouse
11537365Cnes4_mC. neoformans susceptibility locus 4 (mouse)1144449142178449142Mouse
11081167Tir8_mtrypanosome infection response 8 (mouse)1155716221189716369Mouse
1302132Pbw1_mpentobarbital withdrawal QTL 1 (mouse)Not determined1155831765189831892Mouse
1357434Obsty1_mobesity 1 (mouse)Not determined1136209950170210094Mouse
4142159Nba2_mNew Zealand Black autoimmunity 2 (mouse)Not determined151835111185835280Mouse
1301602Bslm4_mbasal locomotor activity 4 (mouse)Not determined1157456299191456436Mouse
1301866Cplaq3_mcircadian period of locomotor activity 3 (mouse)Not determined1155721528189722608Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158468817192468938Mouse
4142149Ctex_mCtla4 expression QTL (mouse)Not determined1153557406175468938Mouse
1301614Cgnz1_mchronic glomerulonephritis in NZM 1 (mouse)Not determined1152038741186038913Mouse
12910521Scgq1_mspontaneous crescentic glomerulonephritis QTL 1 (mouse)1156602037176262693Mouse
12910522Scgq2_mspontaneous crescentic glomerulonephritis QTL 2 (mouse)1147125258171632257Mouse
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
4142014Wbcq5_mwhite blood cell quantitative locus 5 (mouse)Not determined1141095010175095156Mouse
4141245Cq2_mcholesterol QTL 2 (mouse)Not determined1157456299191456436Mouse
4141244Bmd5c_mbone mineral density 5c (mouse)Not determined155526796189526897Mouse
14746980Manh50_mmandible shape 50 (mouse)1134131564168131564Mouse
13464138Hdlq107_mHDL QTL 107 (mouse)1152132744186132744Mouse
1300888Berr1_mberghei resistance locus 1 (mouse)Not determined1164143227190534272Mouse
1301151Hdlq14_mHDL QTL 14 (mouse)Not determined1142489543176489734Mouse
1301149Lrnx12_mlearning-contextual 12 (mouse)Not determined1112008822168186402Mouse
4141233Femwf12_mfemur work to failure 12 (mouse)Not determined141233173175233272Mouse
1301122Cd8mts1_mCD8 T memory cell subset 1 (mouse)Not determined1155831765189831892Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161201261195154279Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167462514195154279Mouse
1301894Skull2_mskull morphology 2 (mouse)Not determined1139602037173602216Mouse
1301385Radpf2_mradiation pulmonary fibrosis 2 (mouse)Not determined1147125258182873798Mouse
1301134Bmd1_mbone mineral density 1 (mouse)Not determined1156602037189303617Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167462514195154279Mouse
13452397Leusq4_mleucocytosis susceptibility QTL 4 (mouse)1156602037170803640Mouse
1357493Lgaq3_mlate growth adjusted QTL 3 (mouse)Not determined1150193673188359312Mouse
11251722Ewc1_methanol withdrawal and consumption 1 (mouse)1152132744186132744Mouse
1302193Cpfd1_mcerebellum pattern fissures (mouse)Not determined1139602037173602216Mouse
10043963Obq25_mobesity QTL 25 (mouse)Not determined1154410512188410512Mouse
13452393Ity3b_mimmunity to S. typhimurium 3b (mouse)1156497439172097436Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159262573193262693Mouse
13452394Leusq1_mleucocytosis susceptibility QTL 1 (mouse)1156602037168186402Mouse
1301408Lore8_mloss of righting induced by ethanol 8 (mouse)Not determined1135877901169878015Mouse
10412074Nhdlt1_mnon-HDL cholesterol and triglyceride levels 1 (mouse)Not determined1153675990187676105Mouse
1357485Lgq4_mlate growth QTL 4 (mouse)Not determined1150193673188359312Mouse
1301932Ssta2_msusceptibility to Salmonella typhimurium antigens 2 (mouse)Not determined1155716221189716369Mouse
27095901Scvln8_msacral vertebrae length 2, 10 week (mouse)194127725172027567Mouse
11049576Lmr8a_mleishmaniasis resistance 8a (mouse)1139602037173602216Mouse
1301458Skts8_mskin tumor susceptibility 8 (mouse)Not determined1135794822169795012Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158468817192468938Mouse
10054490Opefa_mopen field activity (mouse)Not determined1153712853187712853Mouse
1300948Fglu2_mfasting glucose 2 (mouse)Not determined1157456299191456436Mouse
1301467Pcir1_mperiosteal circumference 1 (mouse)Not determined1141233173175233272Mouse
1301722Cia9_mcollagen induced arthritis QTL 9 (mouse)Not determined145783900189303617Mouse
1300696Bpq2_mblood pressure QTL 2 (mouse)Not determined1139602037173602216Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158468817192468938Mouse
4141554Cfmq1_mcystic fibrosis modifier QTL 1 (mouse)Not determined1152038741186038913Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158468817192468938Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158468817192468938Mouse
1301191Stia1_mserum transfer induced arthritis 1 (mouse)Not determined1141233173175233272Mouse
1300934Cfbw1_mcystic fibrosis body weight 1 (mouse)Not determined1145145207179145325Mouse
1301189Lmr8_mleishmaniasis resistance 8 (mouse)Not determined1156602037189303617Mouse
1558720Bpq8_mblood pressure QTL 8 (mouse)Not determined1143284665177284803Mouse
10766456Sle21_msystematic lupus erythematosus susceptibility 21 (mouse)1155831765189831892Mouse
1301710Bmd5_mbone mineral density 5 (mouse)Not determined1139602037173602216Mouse
27095935Ulnl5_mulna length 5, 10 week (mouse)1128727737181327565Mouse
1301232Hcs7_mhepatocarcinogenesis susceptibility 7 (mouse)Not determined1156602037168186402Mouse
10054271Nba9_mNew Zealand Black autoimmunity 9 (mouse)Not determined1155525623189527533Mouse
10054270Nba10_mNew Zealand Black autoimmunity 10 (mouse)Not determined1152794822186438620Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167462514195154279Mouse
1357567Nidd3k_mNidd3 on KK-A<y> (mouse)Not determined7147125258169038913Mouse
4142291Aec2_mautoimmune exocrinopathy 2 (mouse)Not determined52457737182250592Mouse
1300732Melm2_mmelanoma modifier 2 (mouse)Not determined1157456299191456436Mouse
1301216Cbm1_mcerebellum weight 1 (mouse)Not determined1157456299191456436Mouse
27095915Scvln13_msacral vertebrae length 2, 16 week (mouse)1117527730179827565Mouse
11533913Rd6m1_mretinal degeneration 6 modifier 1 (mouse)1141233173175233272Mouse
26884448Sklq1_mskull length QTL 1, 5 week (mouse)175976637181327565Mouse
1300969Sluc5_msusceptibility to lung cancer 5 (mouse)Not determined1151186243185186402Mouse

Markers in Region
Rxrg  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H2.3UniSTS
cM Map188.1UniSTS
G49228  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381167,638,532 - 167,638,746UniSTSGRCm38
MGSCv371169,568,663 - 169,568,877UniSTSGRCm37
Celera1170,068,371 - 170,068,585UniSTS
Cytogenetic Map1H2.3UniSTS
G49237  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381167,639,217 - 167,639,400UniSTSGRCm38
MGSCv371169,569,348 - 169,569,531UniSTSGRCm37
Celera1170,069,055 - 170,069,238UniSTS
Cytogenetic Map1H2.3UniSTS
PMC314362P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381167,627,286 - 167,627,480UniSTSGRCm38
MGSCv371169,557,417 - 169,557,611UniSTSGRCm37
Celera1170,057,148 - 170,057,342UniSTS
Cytogenetic Map1H2.3UniSTS
WI-15938  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381167,639,291 - 167,639,395UniSTSGRCm38
MGSCv371169,569,422 - 169,569,526UniSTSGRCm37
Celera1170,069,129 - 170,069,233UniSTS
Cytogenetic Map1H2.3UniSTS
Rxrg  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H2.3UniSTS
Rxrg  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H2.3UniSTS
Rxrg  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H2.3UniSTS
cM Map188.1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001159731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC093318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC093452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF525492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC058401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM947610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ442702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY769777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  G49237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M84819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S62948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S62952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X76656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000015987   ⟹   ENSMUSP00000015987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1167,425,953 - 167,467,192 (+)Ensembl
GRCm38.p6 Ensembl1167,598,384 - 167,639,623 (+)Ensembl
Ensembl Acc Id: ENSMUST00000111380   ⟹   ENSMUSP00000107011
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1167,445,878 - 167,467,190 (+)Ensembl
GRCm38.p6 Ensembl1167,618,309 - 167,639,621 (+)Ensembl
Ensembl Acc Id: ENSMUST00000111384   ⟹   ENSMUSP00000107015
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1167,426,049 - 167,467,187 (+)Ensembl
GRCm38.p6 Ensembl1167,598,480 - 167,639,618 (+)Ensembl
Ensembl Acc Id: ENSMUST00000111386   ⟹   ENSMUSP00000107017
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1167,426,029 - 167,466,993 (+)Ensembl
GRCm38.p6 Ensembl1167,598,460 - 167,639,424 (+)Ensembl
RefSeq Acc Id: NM_001159731   ⟹   NP_001153203
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391167,445,831 - 167,467,191 (+)NCBI
GRCm381167,618,265 - 167,639,623 (+)NCBI
MGSCv371169,528,493 - 169,569,754 (+)RGD
Celera1170,022,008 - 170,069,461 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001420495   ⟹   NP_001407424
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391167,425,902 - 167,467,191 (+)NCBI
RefSeq Acc Id: NM_001420496   ⟹   NP_001407425
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391167,425,902 - 167,467,191 (+)NCBI
RefSeq Acc Id: NM_009107   ⟹   NP_033133
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391167,425,902 - 167,467,191 (+)NCBI
GRCm381167,598,362 - 167,639,623 (+)ENTREZGENE
MGSCv371169,528,493 - 169,569,754 (+)RGD
Celera1170,022,008 - 170,069,461 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_033133   ⟸   NM_009107
- Peptide Label: isoform 1
- UniProtKB: P28705 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001153203   ⟸   NM_001159731
- Peptide Label: isoform 2
- UniProtKB: E9Q9V9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000107017   ⟸   ENSMUST00000111386
Ensembl Acc Id: ENSMUSP00000107015   ⟸   ENSMUST00000111384
Ensembl Acc Id: ENSMUSP00000107011   ⟸   ENSMUST00000111380
Ensembl Acc Id: ENSMUSP00000015987   ⟸   ENSMUST00000015987
RefSeq Acc Id: NP_001407424   ⟸   NM_001420495
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001407425   ⟸   NM_001420496
- Peptide Label: isoform 4
- UniProtKB: E9Q9V9 (UniProtKB/TrEMBL)
Protein Domains
NR LBD   Nuclear receptor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P28705-F1-model_v2 AlphaFold P28705 1-463 view protein structure

Promoters
RGD ID:6875588
Promoter ID:EPDNEW_M1245
Type:initiation region
Name:Rxrg_1
Description:Mus musculus retinoid X receptor gamma , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1246  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381167,598,371 - 167,598,431EPDNEW
RGD ID:6875590
Promoter ID:EPDNEW_M1246
Type:initiation region
Name:Rxrg_2
Description:Mus musculus retinoid X receptor gamma , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M1245  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381167,618,280 - 167,618,340EPDNEW
RGD ID:6818423
Promoter ID:MM_KWN:2756
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ENSMUST00000111384,   ENSMUST00000111386,   NM_009107
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,528,546 - 169,529,046 (+)MPROMDB
RGD ID:6818422
Promoter ID:MM_KWN:2757
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:NM_001159731
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361169,548,191 - 169,548,691 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98216 AgrOrtholog
Ensembl Genes ENSMUSG00000015843 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000015987 ENTREZGENE
  ENSMUST00000015987.10 UniProtKB/Swiss-Prot
  ENSMUST00000111380 ENTREZGENE
  ENSMUST00000111380.2 UniProtKB/TrEMBL
  ENSMUST00000111384.8 UniProtKB/Swiss-Prot
  ENSMUST00000111386.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuc_recep-AF1 UniProtKB/Swiss-Prot
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hormone_rcpt_NR2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Retinoid-X_rcpt/HNF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20183 UniProtKB/Swiss-Prot
MGD MGI:98216 ENTREZGENE
NCBI Gene 20183 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RETINOIC ACID RECEPTOR RXR-GAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuc_recep-AF1 UniProtKB/Swiss-Prot
  zf-C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rxrg PhenoGen
PRINTS RETINOIDXR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STRDHORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOLI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48508 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9Q9V9 ENTREZGENE, UniProtKB/TrEMBL
  P28705 ENTREZGENE
  Q3V193_MOUSE UniProtKB/TrEMBL
  RXRG_MOUSE UniProtKB/Swiss-Prot