Cap2 (cyclase associated actin cytoskeleton regulatory protein 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Cap2 (cyclase associated actin cytoskeleton regulatory protein 2) Mus musculus
Analyze
Symbol: Cap2
Name: cyclase associated actin cytoskeleton regulatory protein 2
RGD ID: 733379
MGI Page MGI
Description: Predicted to enable actin binding activity; adenylate cyclase binding activity; and identical protein binding activity. Involved in presynaptic actin cytoskeleton organization. Located in postsynaptic density. Is expressed in several structures, including head mesenchyme; heart; metanephros; telencephalon; and vertebral axis musculature. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human CAP2 (cyclase associated actin cytoskeleton regulatory protein 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2810452G09Rik; adenylyl cyclase-associated protein 2; AV045235; CAP, adenylate cyclase-associated protein, 2; CAP, adenylate cyclase-associated protein, 2 (yeast)
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391346,655,379 - 46,803,757 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1346,655,324 - 46,803,757 (+)EnsemblGRCm39 Ensembl
GRCm381346,501,903 - 46,650,281 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1346,501,848 - 46,650,281 (+)EnsemblGRCm38mm10GRCm38
MGSCv371346,597,272 - 46,745,650 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361346,513,119 - 46,661,250 (+)NCBIMGSCv36mm8
Celera1347,582,526 - 47,733,794 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1323.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,7-dihydropurine-6-thione  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
alpha-Zearalanol  (ISO)
AM-251  (ISO)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chlordecone  (EXP)
chloropicrin  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
folic acid  (EXP)
FR900359  (ISO)
furan  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (ISO)
mercaptopurine  (ISO)
methotrexate  (EXP)
methoxychlor  (ISO)
nickel atom  (EXP,ISO)
nitrofen  (ISO)
Nutlin-3  (ISO)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
progesterone  (ISO)
purine-6-thiol  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
taurine  (ISO)
tetrachloromethane  (ISO)
triclosan  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal heart morphology  (IAGP)
abnormal I band morphology  (IAGP)
abnormal impulse conducting system conduction  (IAGP)
abnormal locomotor activation  (IEA)
abnormal M line morphology  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal myocardial fiber physiology  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal sarcomere morphology  (IAGP)
abnormal ventricle myocardium morphology  (IAGP)
atrioventricular block  (IAGP)
cardiac fibrosis  (IAGP)
cardiac interstitial fibrosis  (IAGP)
cataract  (IEA)
congestive heart failure  (IAGP)
decreased aerobic running capacity  (IAGP)
decreased body weight  (IAGP)
decreased circulating triglyceride level  (IEA)
decreased grip strength  (IAGP)
decreased heart left ventricle muscle contractility  (IAGP)
decreased heart rate  (IAGP)
decreased mean corpuscular hemoglobin  (IEA)
decreased myocardial fiber number  (IAGP)
decreased survivor rate  (IAGP)
dilated cardiomyopathy  (IAGP)
dilated heart atrium  (IAGP)
dilated heart left ventricle  (IAGP)
dilated heart right atrium  (IAGP)
dilated heart ventricle  (IAGP)
enlarged heart  (IAGP)
eye inflammation  (IAGP)
increased red blood cell distribution width  (IEA)
increased susceptibility to infection  (IAGP)
microphthalmia  (IAGP)
no abnormal phenotype detected  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
prolonged HV interval  (IAGP)
prolonged PQ interval  (IAGP)
prolonged QRS complex duration  (IAGP)
prolonged QT interval  (IAGP)
prolonged RR interval  (IAGP)
prolonged ST segment  (IEA)
sinus bradycardia  (IAGP)
small pupil  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15004221   PMID:15489334   PMID:16141072   PMID:16141073   PMID:17114649   PMID:17286962  
PMID:17805484   PMID:18246200   PMID:18287559   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22945801   PMID:23431145   PMID:23439681   PMID:25464902   PMID:26616005   PMID:26925136  
PMID:27507934   PMID:27626380   PMID:27880917   PMID:28344592   PMID:28671696   PMID:30562941   PMID:30962377   PMID:31162944   PMID:32325033   PMID:33637797   PMID:33742108   PMID:34204261  
PMID:34321999   PMID:37863260   PMID:38355793   PMID:38713765  


Genomics

Comparative Map Data
Cap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391346,655,379 - 46,803,757 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1346,655,324 - 46,803,757 (+)EnsemblGRCm39 Ensembl
GRCm381346,501,903 - 46,650,281 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1346,501,848 - 46,650,281 (+)EnsemblGRCm38mm10GRCm38
MGSCv371346,597,272 - 46,745,650 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361346,513,119 - 46,661,250 (+)NCBIMGSCv36mm8
Celera1347,582,526 - 47,733,794 (+)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1323.83NCBI
CAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38617,393,595 - 17,557,780 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl617,393,595 - 17,557,780 (+)EnsemblGRCh38hg38GRCh38
GRCh37617,393,826 - 17,558,011 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36617,501,715 - 17,666,002 (+)NCBINCBI36Build 36hg18NCBI36
Build 34617,501,714 - 17,666,000NCBI
Celera618,632,068 - 18,796,067 (+)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef617,340,107 - 17,502,548 (+)NCBIHuRef
CHM1_1617,396,197 - 17,560,514 (+)NCBICHM1_1
T2T-CHM13v2.0617,265,693 - 17,429,911 (+)NCBIT2T-CHM13v2.0
Cap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81718,260,462 - 18,409,681 (-)NCBIGRCr8
mRatBN7.21718,054,234 - 18,203,453 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1718,054,431 - 18,203,373 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1717,941,405 - 18,089,565 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01719,545,274 - 19,693,435 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01717,868,534 - 18,016,688 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01718,441,614 - 18,592,866 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1718,442,127 - 18,592,750 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01719,345,220 - 19,493,214 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1717,763,871 - 17,910,638 (-)NCBICelera
Cytogenetic Map17p14NCBI
Cap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554838,484,427 - 8,603,234 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554838,484,427 - 8,602,748 (-)NCBIChiLan1.0ChiLan1.0
CAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2532,059,995 - 32,223,059 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1628,045,423 - 28,208,045 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0617,248,751 - 17,411,593 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1617,608,046 - 17,770,160 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl617,608,046 - 17,770,160 (+)Ensemblpanpan1.1panPan2
CAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13516,336,716 - 16,476,166 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3516,336,753 - 16,474,913 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3516,289,467 - 16,426,701 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03516,443,075 - 16,582,657 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3516,442,937 - 16,582,653 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13516,259,869 - 16,397,153 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03516,312,854 - 16,450,700 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03517,646,682 - 17,784,200 (+)NCBIUU_Cfam_GSD_1.0
Cap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049468,228,988 - 8,335,156 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365523,395,649 - 3,501,940 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365523,395,785 - 3,501,949 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl713,211,574 - 13,350,961 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1713,211,110 - 13,350,966 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2714,007,002 - 14,053,037 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11754,575,289 - 54,742,565 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1754,574,145 - 54,742,757 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604417,486,737 - 17,764,077 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247568,989,203 - 9,174,283 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247568,990,151 - 9,174,208 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cap2
4305 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:748
Count of miRNA genes:357
Interacting mature miRNAs:394
Transcripts:ENSMUST00000021802, ENSMUST00000119341, ENSMUST00000126687
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300561Heal7_mwound healing/regeneration 7 (mouse)Not determined133614482070144904Mouse
1357591Tesq1_mtestis weight QTL 1 (mouse)Not determined132061551255720517Mouse
1301015Sysbp2_msystolic blood pressure 2 (mouse)Not determined132047761259821605Mouse
4142331Bxs6_mBXSB/MpJ autoimmune nephritis 6 (mouse)Not determined4521044283744746Mouse
12738439Twq4_mtestis weight QTL 4 (mouse)133112911065129110Mouse
4142009Pregq3_mpregnancy QTL 3 (mouse)Not determined132061551272385189Mouse
1357587Pfat3_mpredicted fat percentage 3 (mouse)Not determined133610153070101640Mouse
10401111Pgia40_mproteoglycan induced arthritis 40 (mouse)Not determined132791846961918560Mouse
10412109Bxs7_mBXSB/MpJ autoimmune nephritis 7 (mouse)Not determined134521044283744746Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
10755517Chol15_mcholesterol 15 (mouse)133096946764969467Mouse
15039353Nmrs35_mNAFLD-associated magnetic resonance shift 35 (mouse)134058825374588253Mouse
1302157Bwem2_mbody weight day 30 males 2 (mouse)Not determined133962924973629397Mouse
13463469Gssq1_mglomerulosclerosis severity QTL 1 (mouse)131906090853061050Mouse
1301299Sluc23_msusceptibility to lung cancer 23 (mouse)Not determined133492194368922081Mouse
12880423V25Dq7_mvitamin D inactive form serum level QTL 7 (mouse)131958398353583983Mouse
1558898Hpi1_mhapatic PMN infiltration 1 (mouse)Not determined13441402553101640Mouse
4142489Ath25_matherosclerosis 25 (mouse)Not determined2583652959836529Mouse
10755533Chol18_mcholesterol 18 (mouse)133096946764969467Mouse
1300985Bmd13_mbone mineral density 13 (mouse)Not determined133962924973629397Mouse
1301880Hypt_mhypertension (mouse)Not determined131815679252156924Mouse
10045618Heal17_mwound healing/regeneration 17 (mouse)Not determined132074693954747056Mouse
10045621Heal21_mwound healing/regeneration 21 (mouse)Not determined132821737962217515Mouse
1300862Cfbw5_mcystic fibrosis body weight 5 (mouse)Not determined133872035872720517Mouse
1300668Pas10_mpulmonary adenoma susceptibility 10 (mouse)Not determined134148904275489158Mouse
26884393Humsd7_mhumerus midshaft diameter 7, 16 week (mouse)13395000076048119Mouse
1300710Pcd4ts2_mp-glycoprotein positive CD4 T cell subset 2 (mouse)Not determined132821044262210544Mouse
1301734Acsns2_mAngiostrongylus costaricensis nematode susceptibility 2 (mouse)Not determined133610153070101640Mouse
14696729Kidlq2_mkidney weight, left QTL 2 (mouse)133134473665344736Mouse
12738427Lfibq24_mliver fibrosis QTL 24 (mouse)134425810752758667Mouse
1301801Cpfd5_mcerebellum pattern fissures (mouse)Not determined133962924973629397Mouse
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
1357802Vtbt15_mvertebral trabecular bone trait 15 (mouse)Not determined132821737962217515Mouse

Markers in Region
AV045235  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381346,648,368 - 46,648,450UniSTSGRCm38
MGSCv371346,743,737 - 46,743,819UniSTSGRCm37
Celera1347,731,877 - 47,731,959UniSTS
Cytogenetic Map13A5UniSTS
Whitehead/MRC_RH13482.97UniSTS
D13Mit181  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381346,508,401 - 46,508,536UniSTSGRCm38
MGSCv371346,603,770 - 46,603,905UniSTSGRCm37
Celera1347,589,004 - 47,589,139UniSTS
Cytogenetic Map13A5UniSTS
cM Map1330.0UniSTS
Whitehead Genetic1316.4UniSTS
Whitehead/MRC_RH13480.65UniSTS
Whitehead_YAC13 UniSTS
UniSTS:237008  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381346,648,591 - 46,648,829UniSTSGRCm38
MGSCv371346,743,960 - 46,744,198UniSTSGRCm37
Celera1347,732,100 - 47,732,338UniSTS
Cytogenetic Map13A5UniSTS
Cap2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381346,648,810 - 46,649,357UniSTSGRCm38
MGSCv371346,744,179 - 46,744,726UniSTSGRCm37
Celera1347,732,319 - 47,732,866UniSTS
Cytogenetic Map13A5UniSTS
cM Map13 UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_026056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006516946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030247379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC138329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK013331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK014979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK035556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076737 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC050752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM899250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY127376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000021802   ⟹   ENSMUSP00000021802
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1346,655,324 - 46,803,757 (+)Ensembl
GRCm38.p6 Ensembl1346,501,848 - 46,650,281 (+)Ensembl
Ensembl Acc Id: ENSMUST00000119341   ⟹   ENSMUSP00000112952
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1346,655,601 - 46,803,111 (+)Ensembl
GRCm38.p6 Ensembl1346,502,125 - 46,649,635 (+)Ensembl
Ensembl Acc Id: ENSMUST00000126687   ⟹   ENSMUSP00000153072
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1346,793,534 - 46,800,048 (+)Ensembl
GRCm38.p6 Ensembl1346,640,058 - 46,646,572 (+)Ensembl
Ensembl Acc Id: ENSMUST00000225444
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1346,762,990 - 46,791,479 (+)Ensembl
GRCm38.p6 Ensembl1346,609,514 - 46,638,003 (+)Ensembl
Ensembl Acc Id: ENSMUST00000225824   ⟹   ENSMUSP00000153125
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1346,655,642 - 46,802,002 (+)Ensembl
GRCm38.p6 Ensembl1346,502,166 - 46,648,526 (+)Ensembl
RefSeq Acc Id: NM_026056   ⟹   NP_080332
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391346,655,379 - 46,803,757 (+)NCBI
GRCm381346,501,903 - 46,650,281 (+)ENTREZGENE
MGSCv371346,597,272 - 46,745,650 (+)RGD
Celera1347,582,526 - 47,733,794 (+)RGD
cM Map13 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006516946   ⟹   XP_006517009
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391346,656,353 - 46,803,122 (+)NCBI
GRCm381346,502,875 - 46,649,646 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030247379   ⟹   XP_030103239
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391346,678,419 - 46,803,122 (+)NCBI
GRCm381346,524,943 - 46,649,646 (+)NCBI
Sequence:
RefSeq Acc Id: NP_080332   ⟸   NM_026056
- UniProtKB: Q80YU7 (UniProtKB/Swiss-Prot),   Q9D6L0 (UniProtKB/Swiss-Prot),   Q9CYT6 (UniProtKB/Swiss-Prot),   A0A286YCS6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006517009   ⟸   XM_006516946
- Peptide Label: isoform X1
- UniProtKB: A0A286YCS6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030103239   ⟸   XM_030247379
- Peptide Label: isoform X2
- UniProtKB: Q9CYT6 (UniProtKB/Swiss-Prot),   Q80YU7 (UniProtKB/Swiss-Prot),   Q9D6L0 (UniProtKB/Swiss-Prot),   A0A286YCS6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000112952   ⟸   ENSMUST00000119341
Ensembl Acc Id: ENSMUSP00000153125   ⟸   ENSMUST00000225824
Ensembl Acc Id: ENSMUSP00000153072   ⟸   ENSMUST00000126687
Ensembl Acc Id: ENSMUSP00000021802   ⟸   ENSMUST00000021802
Protein Domains
C-CAP/cofactor C-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9CYT6-F1-model_v2 AlphaFold Q9CYT6 1-476 view protein structure

Promoters
RGD ID:8680232
Promoter ID:EPDNEW_M18147
Type:initiation region
Name:Cap2_1
Description:Mus musculus CAP, adenylate cyclase-associated protein, 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18148  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381346,501,842 - 46,501,902EPDNEW
RGD ID:8680234
Promoter ID:EPDNEW_M18148
Type:initiation region
Name:Cap2_2
Description:Mus musculus CAP, adenylate cyclase-associated protein, 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M18147  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381346,502,177 - 46,502,237EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914502 AgrOrtholog
Ensembl Genes ENSMUSG00000021373 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000021802 ENTREZGENE
  ENSMUST00000021802.16 UniProtKB/Swiss-Prot
  ENSMUST00000119341.2 UniProtKB/TrEMBL
  ENSMUST00000126687.2 UniProtKB/TrEMBL
  ENSMUST00000225824 ENTREZGENE
  ENSMUST00000225824.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.160.20.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Adenylate_cyclase-assoc_CAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Adenylate_cyclase-assoc_CAP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Adenylate_cyclase-assoc_CAP_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-CAP_CF_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP/MinC_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP_CS_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP_CS_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CARP_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:67252 UniProtKB/Swiss-Prot
MGD MGI:1914502 ENTREZGENE
NCBI Gene 67252 ENTREZGENE
PANTHER PTHR10652 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10652:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CAP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cap2 PhenoGen
PROSITE C_CAP_COFACTOR_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CAP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CARP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
  SSF101278 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF69340 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286YCN6_MOUSE UniProtKB/TrEMBL
  A0A286YCS6 ENTREZGENE, UniProtKB/TrEMBL
  CAP2_MOUSE UniProtKB/Swiss-Prot
  D3YTR7_MOUSE UniProtKB/TrEMBL
  Q80YU7 ENTREZGENE
  Q8BKZ3_MOUSE UniProtKB/TrEMBL
  Q9CYT6 ENTREZGENE
  Q9D6L0 ENTREZGENE
UniProt Secondary Q80YU7 UniProtKB/Swiss-Prot
  Q9D6L0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Cap2  cyclase associated actin cytoskeleton regulatory protein 2  Cap2  CAP, adenylate cyclase-associated protein, 2 (yeast)  Symbol and/or name change 5135510 APPROVED