Amhr2 (anti-Mullerian hormone type 2 receptor) - Rat Genome Database

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Gene: Amhr2 (anti-Mullerian hormone type 2 receptor) Mus musculus
Analyze
Symbol: Amhr2
Name: anti-Mullerian hormone type 2 receptor
RGD ID: 733277
MGI Page MGI
Description: Predicted to enable several functions, including anti-Mullerian hormone receptor activity; protein homodimerization activity; and transforming growth factor beta receptor activity, type II. Acts upstream of or within sex differentiation. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including bone; early embryo; forebrain; genitourinary system; and spleen. Used to study persistent Mullerian duct syndrome. Human ortholog(s) of this gene implicated in persistent Mullerian duct syndrome. Orthologous to human AMHR2 (anti-Mullerian hormone receptor type 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AMH type II receptor; anti-Muellerian hormone type II receptor; anti-Muellerian hormone type-2 receptor; anti-Mullerian hormone type 2 receptor delta 2; anti-Mullerian hormone type 2 receptor delta 9/10; C14; M; MGC141312; MIS type II receptor; Misiir; Misrii; Mrii
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,353,437 - 102,363,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,353,802 - 102,363,068 (+)EnsemblGRCm39 Ensembl
GRCm3815102,445,002 - 102,454,640 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,445,367 - 102,454,633 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715102,275,798 - 102,285,070 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,273,454 - 102,282,664 (+)NCBIMGSCv36mm8
Celera15104,603,320 - 104,612,566 (+)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.58NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal circulating hormone level  (IAGP)
abnormal cumulus expansion  (IAGP)
abnormal DNA methylation  (IAGP)
abnormal endometrial gland development  (IAGP)
abnormal endometrial gland morphology  (IAGP)
abnormal endometrium morphology  (IAGP)
abnormal estrous cycle  (IAGP)
abnormal granulosa cell morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal maternal decidual layer morphology  (IAGP)
abnormal meiosis  (IAGP)
abnormal Mullerian duct morphology  (IAGP)
abnormal myometrium morphology  (IAGP)
abnormal oocyte morphology  (IAGP)
abnormal ovarian follicle morphology  (IAGP)
abnormal ovarian follicle number  (IAGP)
abnormal ovarian folliculogenesis  (IAGP)
abnormal ovary development  (IAGP)
abnormal ovary morphology  (IAGP)
abnormal ovary physiology  (IAGP)
abnormal oviduct morphology  (IAGP)
abnormal oviduct transport  (IAGP)
abnormal ovulation  (IAGP)
abnormal placenta development  (IAGP)
abnormal placenta labyrinth morphology  (IAGP)
abnormal placenta vasculature  (IAGP)
abnormal placental labyrinth vasculature morphology  (IAGP)
abnormal pregnancy  (IAGP)
abnormal preimplantation embryo development  (IAGP)
abnormal secondary ovarian follicle morphology  (IAGP)
abnormal seminiferous tubule epithelium morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal Sertoli cell barrier function  (IAGP)
abnormal Sertoli cell morphology  (IAGP)
abnormal sex determination  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal tertiary ovarian follicle morphology  (IAGP)
abnormal testis cord formation  (IAGP)
abnormal testis development  (IAGP)
abnormal testis morphology  (IAGP)
abnormal trophoblast layer morphology  (IAGP)
abnormal uterine environment  (IAGP)
abnormal uterus morphology  (IAGP)
absent corpus luteum  (IAGP)
absent cumulus expansion  (IAGP)
absent estrous cycle  (IAGP)
absent oocytes  (IAGP)
absent placental labyrinth  (IAGP)
absent sexual maturation  (IAGP)
anemia  (IAGP)
arrest of male meiosis  (IAGP)
arrest of spermatogenesis  (IAGP)
ascites  (IAGP)
asthenozoospermia  (IAGP)
azoospermia  (IAGP)
cryptorchism  (IAGP)
decreased circulating estradiol level  (IAGP)
decreased circulating luteinizing hormone level  (IAGP)
decreased circulating progesterone level  (IAGP)
decreased circulating testosterone level  (IAGP)
decreased corpora lutea number  (IAGP)
decreased endometrial gland number  (IAGP)
decreased granulosa cell proliferation  (IAGP)
decreased hematocrit  (IAGP)
decreased litter size  (IAGP)
decreased male germ cell number  (IAGP)
decreased mature ovarian follicle number  (IAGP)
decreased oocyte number  (IAGP)
decreased ovary weight  (IAGP)
decreased ovulation rate  (IAGP)
decreased primary ovarian follicle number  (IAGP)
decreased primordial ovarian follicle number  (IAGP)
decreased renal glomerulus number  (IAGP)
decreased secondary ovarian follicle number  (IAGP)
decreased sperm progressive motility  (IAGP)
decreased spongiotrophoblast cell number  (IAGP)
decreased superovulation rate  (IAGP)
decreased tertiary ovarian follicle number  (IAGP)
decreased testis weight  (IAGP)
decreased uterine NK cell number  (IAGP)
decreased uterus weight  (IAGP)
dilated oviduct  (IAGP)
dilated uterus  (IAGP)
disheveled coat  (IAGP)
early reproductive senescence  (IAGP)
edema  (IAGP)
embryonic lethality, incomplete penetrance  (IAGP)
endometrium fibrosis  (IAGP)
endometrium hyperplasia  (IAGP)
extramedullary hematopoiesis  (IAGP)
failure of embryo implantation  (IAGP)
failure of Mullerian duct regression  (IAGP)
failure of superovulation  (IAGP)
female infertility  (IAGP)
hemoperitoneum  (IAGP)
hemorrhage  (IAGP)
impaired embryo implantation  (IAGP)
impaired fertilization  (IAGP)
impaired ovarian folliculogenesis  (IAGP)
increased atretic ovarian follicle number  (IAGP)
increased carcinoma incidence  (IAGP)
increased circulating estradiol level  (IAGP)
increased circulating follicle stimulating hormone level  (IAGP)
increased circulating luteinizing hormone level  (IAGP)
increased circulating progesterone level  (IAGP)
increased corpora lutea number  (IAGP)
increased follicle stimulating hormone level  (IAGP)
increased granulosa cell tumor incidence  (IAGP)
increased Leydig cell number  (IAGP)
increased Leydig cell tumor incidence  (IAGP)
increased male germ cell apoptosis  (IAGP)
increased metastatic potential  (IAGP)
increased miscarriage rate  (IAGP)
increased ovarian carcinoma incidence  (IAGP)
increased ovary adenoma incidence  (IAGP)
increased ovary tumor incidence  (IAGP)
increased ovary weight  (IAGP)
increased secondary ovarian follicle number  (IAGP)
increased Sertoli cell proliferation  (IAGP)
increased testis tumor incidence  (IAGP)
increased trophoblast giant cell number  (IAGP)
increased tumor incidence  (IAGP)
infertility  (IAGP)
internal male genitalia hypoplasia  (IAGP)
male infertility  (IAGP)
male pseudohermaphroditism  (IAGP)
multinucleated giant male germ cells  (IAGP)
oligozoospermia  (IAGP)
oocyte degeneration  (IAGP)
ovarian follicular cyst  (IAGP)
ovary cyst  (IAGP)
ovary hemorrhage  (IAGP)
ovary hypoplasia  (IAGP)
polyovular ovarian follicle  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
premature ovarian failure  (IAGP)
prolonged estrous cycle  (IAGP)
prolonged estrus  (IAGP)
pulmonary embolism  (IAGP)
reduced female fertility  (IAGP)
reduced male fertility  (IAGP)
secondary sex reversal  (IAGP)
seminiferous tubule degeneration  (IAGP)
short diestrus  (IAGP)
short estrus  (IAGP)
short oviduct  (IAGP)
short uterine horn  (IAGP)
small adrenal glands  (IAGP)
small ovary  (IAGP)
small seminiferous tubules  (IAGP)
small testis  (IAGP)
small uterus  (IAGP)
suppressed circulating follicle stimulating hormone level  (IAGP)
testicular atrophy  (IAGP)
testis hypoplasia  (IAGP)
thin myometrium  (IAGP)
uterus hyperplasia  (IAGP)
vaginal hemorrhage  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Mullerian inhibiting substance type II receptor (MISIIR): a novel, tissue-specific target expressed by gynecologic cancers. Bakkum-Gamez JN, etal., Gynecol Oncol. 2008 Jan;108(1):141-8. Epub 2007 Nov 7.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. The expression of Mullerian inhibiting substance/anti-Mullerian hormone type II receptor protein and mRNA in benign, borderline and malignant ovarian neoplasia. Song JY, etal., Int J Oncol. 2009 Jun;34(6):1583-91.
Additional References at PubMed
PMID:7488027   PMID:8895659   PMID:9260931   PMID:9299437   PMID:9501316   PMID:9510068   PMID:9751506   PMID:9790192   PMID:10571183   PMID:11376112   PMID:11880357   PMID:11960012  
PMID:12368913   PMID:12477932   PMID:12649204   PMID:14610273   PMID:14628051   PMID:14656471   PMID:14695376   PMID:14701941   PMID:15118069   PMID:15342483   PMID:15489334   PMID:15590666  
PMID:16141072   PMID:16230381   PMID:16256976   PMID:16488995   PMID:16513794   PMID:16700072   PMID:17142319   PMID:17404209   PMID:17420277   PMID:17510234   PMID:17532316   PMID:17609433  
PMID:17955388   PMID:17967875   PMID:18213646   PMID:18322278   PMID:18391535   PMID:18395837   PMID:18480464   PMID:18506027   PMID:18599617   PMID:18628394   PMID:18687666   PMID:18687735  
PMID:18703422   PMID:18703631   PMID:18796535   PMID:18799693   PMID:18809571   PMID:19169742   PMID:19176883   PMID:19196835   PMID:19197916   PMID:19237610   PMID:19359476   PMID:19403928  
PMID:19679546   PMID:19794154   PMID:19799966   PMID:19819941   PMID:19843854   PMID:20363875   PMID:20371632   PMID:20375256   PMID:20498064   PMID:20501640   PMID:20805501   PMID:20808952  
PMID:20858757   PMID:21172404   PMID:21248289   PMID:21267068   PMID:21307272   PMID:21333348   PMID:21363919   PMID:21423204   PMID:21490063   PMID:21570712   PMID:21664244   PMID:21695255  
PMID:21731673   PMID:21809434   PMID:21820362   PMID:21832168   PMID:21860425   PMID:21868453   PMID:21873635   PMID:21905163   PMID:22028666   PMID:22128018   PMID:22253774   PMID:22308459  
PMID:22331912   PMID:22396451   PMID:22402963   PMID:22419830   PMID:22461617   PMID:22560297   PMID:22791749   PMID:22871496   PMID:22916036   PMID:22962306   PMID:22970108   PMID:23213481  
PMID:23274689   PMID:23276799   PMID:23322722   PMID:23406467   PMID:23471215   PMID:23475984   PMID:23624077   PMID:23904126   PMID:24170201   PMID:24174323   PMID:24264574   PMID:24362065  
PMID:24371124   PMID:24501173   PMID:24506537   PMID:24552399   PMID:24552588   PMID:24656822   PMID:24823394   PMID:24877631   PMID:24952961   PMID:24983622   PMID:25165122   PMID:25189766  
PMID:25243859   PMID:25246579   PMID:25273528   PMID:25815421   PMID:26027919   PMID:26039990   PMID:26061565   PMID:26193636   PMID:26623518   PMID:26667040   PMID:26678830   PMID:26753790  
PMID:26842836   PMID:26843448   PMID:26962117   PMID:26964623   PMID:27084580   PMID:27159635   PMID:27194944   PMID:27206316   PMID:27281705   PMID:27309940   PMID:27335065   PMID:27344183  
PMID:27354067   PMID:27358915   PMID:28123059   PMID:28426816   PMID:28506985   PMID:28520915   PMID:28827707   PMID:28938492   PMID:29126187   PMID:29860390   PMID:29911998   PMID:30010727  
PMID:30061417   PMID:30260703   PMID:30850578   PMID:30877763   PMID:31202927   PMID:31232694   PMID:31291191   PMID:31461657   PMID:31575647   PMID:31930396   PMID:32099945   PMID:32274496  
PMID:32402291   PMID:32497036   PMID:32520726   PMID:32534604   PMID:32546756   PMID:32934215   PMID:32968170   PMID:33244099   PMID:33262282   PMID:33359762   PMID:33441767   PMID:33496365  
PMID:33980714   PMID:34402888   PMID:34475109   PMID:35396990   PMID:35909540   PMID:35973717   PMID:36130202   PMID:36155779   PMID:36282915   PMID:36440965   PMID:36555314   PMID:36721982  
PMID:37453057   PMID:37494420   PMID:37685880   PMID:37856394   PMID:37887344   PMID:37973188  


Genomics

Comparative Map Data
Amhr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915102,353,437 - 102,363,075 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15102,353,802 - 102,363,068 (+)EnsemblGRCm39 Ensembl
GRCm3815102,445,002 - 102,454,640 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,445,367 - 102,454,633 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715102,275,798 - 102,285,070 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615102,273,454 - 102,282,664 (+)NCBIMGSCv36mm8
Celera15104,603,320 - 104,612,566 (+)NCBICelera
Cytogenetic Map15F3NCBI
cM Map1557.58NCBI
AMHR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381253,423,855 - 53,431,672 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1253,423,855 - 53,431,672 (+)EnsemblGRCh38hg38GRCh38
GRCh371253,817,639 - 53,825,456 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361252,103,908 - 52,111,579 (+)NCBINCBI36Build 36hg18NCBI36
Build 341252,103,907 - 52,111,579NCBI
Celera1253,467,836 - 53,475,515 (+)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,858,022 - 50,865,704 (+)NCBIHuRef
CHM1_11253,784,835 - 53,792,514 (+)NCBICHM1_1
T2T-CHM13v2.01253,389,898 - 53,397,715 (+)NCBIT2T-CHM13v2.0
Amhr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87135,454,517 - 135,470,183 (+)NCBIGRCr8
mRatBN7.27133,579,152 - 133,588,874 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7133,579,393 - 133,588,258 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7135,335,126 - 135,343,991 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07137,564,494 - 137,573,360 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07137,550,745 - 137,559,612 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07144,052,202 - 144,060,678 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7144,052,061 - 144,060,685 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,844,072 - 141,852,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47141,203,832 - 141,212,653 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17141,280,268 - 141,289,089 (+)NCBI
Celera7130,006,948 - 130,015,487 (+)NCBICelera
Cytogenetic Map7q36NCBI
Amhr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458694,055 - 702,778 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458693,434 - 703,026 (+)NCBIChiLan1.0ChiLan1.0
AMHR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21040,750,644 - 40,762,817 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11240,747,448 - 40,759,581 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01235,323,133 - 35,331,092 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,107,363 - 36,115,175 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,107,501 - 36,115,175 (-)Ensemblpanpan1.1panPan2
AMHR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,788,420 - 1,795,601 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,789,681 - 1,795,533 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2744,455,814 - 44,462,993 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,791,762 - 1,796,819 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1271,809,299 - 1,816,478 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,793,536 - 1,800,715 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,856,852 - 44,864,032 (+)NCBIUU_Cfam_GSD_1.0
Amhr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494562,452,033 - 62,462,933 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,705,350 - 10,713,517 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,706,043 - 10,712,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AMHR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,642,823 - 18,648,848 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,642,212 - 18,648,859 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2519,078,369 - 19,085,012 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AMHR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,524,864 - 49,534,774 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1149,525,641 - 49,534,712 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037196,524,251 - 196,533,349 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Amhr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249041,520,572 - 1,530,908 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249041,520,450 - 1,535,291 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Amhr2
200 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:391
Count of miRNA genes:259
Interacting mature miRNAs:283
Transcripts:ENSMUST00000023809, ENSMUST00000161376, ENSMUST00000162893
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92788640103425899Mouse
14700689Carg5_mCandida albicans resistance gene 5 (mouse)1597697881103008427Mouse
11528547Sluc34_msusceptibility to lung cancer 34 (mouse)1597884933102896555Mouse

Markers in Region
Amhr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3815102,453,133 - 102,454,379UniSTSGRCm38
MGSCv3715102,283,564 - 102,284,810UniSTSGRCm37
Celera15104,611,064 - 104,612,306UniSTS
Cytogenetic Map15F3UniSTS
cM Map1557.4UniSTS
cM Map1557.4UniSTS
UniSTS:237406  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3815102,454,406 - 102,454,631UniSTSGRCm38
MGSCv3715102,284,837 - 102,285,062UniSTSGRCm37
Celera15104,612,333 - 104,612,558UniSTS
Cytogenetic Map15F3UniSTS
cM Map1557.4UniSTS
Amhr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F3UniSTS
Amhr2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F3UniSTS
cM Map1557.4UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000023809   ⟹   ENSMUSP00000023809
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl15102,353,802 - 102,363,065 (+)Ensembl
GRCm38.p6 Ensembl15102,445,367 - 102,454,630 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161376
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl15102,360,758 - 102,361,306 (+)Ensembl
GRCm38.p6 Ensembl15102,452,323 - 102,452,871 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162893   ⟹   ENSMUSP00000123735
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl15102,360,594 - 102,362,980 (+)Ensembl
GRCm38.p6 Ensembl15102,452,159 - 102,454,545 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229278   ⟹   ENSMUSP00000154968
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl15102,353,871 - 102,363,068 (+)Ensembl
GRCm38.p6 Ensembl15102,445,436 - 102,454,633 (+)Ensembl
RefSeq Acc Id: ENSMUST00000229566   ⟹   ENSMUSP00000155001
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl15102,353,883 - 102,354,832 (+)Ensembl
GRCm38.p6 Ensembl15102,445,448 - 102,446,397 (+)Ensembl
RefSeq Acc Id: NM_001356575   ⟹   NP_001343504
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3915102,353,437 - 102,363,074 (+)NCBI
GRCm3815102,445,002 - 102,454,639 (+)NCBI
Sequence:
RefSeq Acc Id: NM_144547   ⟹   NP_653130
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3915102,353,802 - 102,363,074 (+)NCBI
GRCm3815102,445,367 - 102,454,639 (+)NCBI
MGSCv3715102,275,798 - 102,285,070 (+)RGD
Celera15104,603,320 - 104,612,566 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006520294   ⟹   XP_006520357
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3915102,353,647 - 102,363,075 (+)NCBI
GRCm3815102,445,220 - 102,454,640 (+)NCBI
Sequence:
RefSeq Acc Id: NP_653130   ⟸   NM_144547
- Peptide Label: precursor
- UniProtKB: Q0VDQ4 (UniProtKB/Swiss-Prot),   Q8K592 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006520357   ⟸   XM_006520294
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001343504   ⟸   NM_001356575
- Peptide Label: precursor
- UniProtKB: Q8K592 (UniProtKB/Swiss-Prot),   Q0VDQ4 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000123735   ⟸   ENSMUST00000162893
RefSeq Acc Id: ENSMUSP00000155001   ⟸   ENSMUST00000229566
RefSeq Acc Id: ENSMUSP00000154968   ⟸   ENSMUST00000229278
RefSeq Acc Id: ENSMUSP00000023809   ⟸   ENSMUST00000023809
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K592-F1-model_v2 AlphaFold Q8K592 1-568 view protein structure

Promoters
RGD ID:8685206
Promoter ID:EPDNEW_M20634
Type:initiation region
Name:Amhr2_1
Description:Mus musculus anti-Mullerian hormone type 2 receptor , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3815102,445,394 - 102,445,454EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:105062 AgrOrtholog
Ensembl Genes ENSMUSG00000023047 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023809 ENTREZGENE
  ENSMUST00000023809.11 UniProtKB/Swiss-Prot
  ENSMUST00000162893.2 UniProtKB/TrEMBL
  ENSMUST00000229278.2 UniProtKB/TrEMBL
  ENSMUST00000229566.2 UniProtKB/TrEMBL
Gene3D-CATH 2.10.60.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Anti-muellerian_hrmn_rcpt_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Snake_toxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGFB_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:110542 UniProtKB/Swiss-Prot
MGD MGI:105062 ENTREZGENE
NCBI Gene 110542 ENTREZGENE
PANTHER ANTI-MUELLERIAN HORMONE TYPE-2 RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PK_Tyr_Ser-Thr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Amhr2 PhenoGen
PIRSF AMHRII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57302 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8VHE2_MOUSE UniProtKB/TrEMBL
  A0A2R8W6H9_MOUSE UniProtKB/TrEMBL
  AMHR2_MOUSE UniProtKB/Swiss-Prot
  F6V9X7_MOUSE UniProtKB/TrEMBL
  Q0VDQ4 ENTREZGENE
  Q8K592 ENTREZGENE
  R4JKA2_MOUSE UniProtKB/TrEMBL
  R4JNM3_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q0VDQ4 UniProtKB/Swiss-Prot