Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Itgae | Mouse | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of ITGAE mRNA | CTD | PMID:28960355 | Itgae | Mouse | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ITGAE mRNA | CTD | PMID:22206623 | Itgae | Mouse | 17beta-estradiol | increases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of ITGAE mRNA | CTD | PMID:17010207 | Itgae | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ITGAE mRNA | CTD | PMID:21570461 and PMID:26377647 | Itgae | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ITGAE mRNA | CTD | PMID:33387578 | Itgae | Mouse | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:38648751 | Itgae | Mouse | 2,6-dinitrotoluene | affects expression | ISO | Itgae (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of ITGAE mRNA | CTD | PMID:21346803 | Itgae | Mouse | 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid | increases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Am 580 results in increased expression of ITGAE mRNA | CTD | PMID:16982809 | Itgae | Mouse | acrylamide | decreases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Acrylamide results in decreased expression of ITGAE mRNA | CTD | PMID:28959563 | Itgae | Mouse | aflatoxin B1 | increases methylation | ISO | ITGAE (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of ITGAE intron | CTD | PMID:30157460 | Itgae | Mouse | arsane | affects methylation | ISO | ITGAE (Homo sapiens) | 6480464 | Arsenic affects the methylation of ITGAE gene | CTD | PMID:25304211 | Itgae | Mouse | arsenic atom | affects methylation | ISO | ITGAE (Homo sapiens) | 6480464 | Arsenic affects the methylation of ITGAE gene | CTD | PMID:25304211 | Itgae | Mouse | arsenite(3-) | increases methylation | ISO | ITGAE (Homo sapiens) | 6480464 | arsenite results in increased methylation of ITGAE promoter | CTD | PMID:23974009 | Itgae | Mouse | arsenite(3-) | multiple interactions | ISO | ITGAE (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to ITGAE mRNA] | CTD | PMID:32406909 | Itgae | Mouse | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ITGAE mRNA] | CTD | PMID:22228805 | Itgae | Mouse | benzo[e]pyrene | decreases methylation | ISO | ITGAE (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of ITGAE intron | CTD | PMID:30157460 | Itgae | Mouse | bisphenol A | decreases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ITGAE mRNA | CTD | PMID:25181051 and PMID:34947998 | Itgae | Mouse | bisphenol A | multiple interactions | ISO | ITGAE (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ITGAE gene | CTD | PMID:31601247 | Itgae | Mouse | bisphenol A | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ITGAE protein | CTD | PMID:33376534 | Itgae | Mouse | buta-1,3-diene | decreases expression | EXP | | 6480464 | 1 and 3-butadiene results in decreased expression of ITGAE mRNA | CTD | PMID:29038090 | Itgae | Mouse | butan-1-ol | multiple interactions | ISO | ITGAE (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of ITGAE mRNA | CTD | PMID:29432896 | Itgae | Mouse | cadmium dichloride | increases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of ITGAE mRNA | CTD | PMID:12160620 | Itgae | Mouse | cadmium dichloride | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of ITGAE mRNA | CTD | PMID:38382870 | Itgae | Mouse | captan | decreases expression | EXP | | 6480464 | Captan results in decreased expression of ITGAE mRNA | CTD | PMID:31558096 | Itgae | Mouse | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in increased expression of ITGAE mRNA | CTD | PMID:25554681 | Itgae | Mouse | chloropicrin | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of ITGAE mRNA | CTD | PMID:26352163 | Itgae | Mouse | chromium(6+) | affects expression | EXP | | 6480464 | chromium hexavalent ion affects the expression of ITGAE mRNA | CTD | PMID:28472532 | Itgae | Mouse | cisplatin | increases response to substance | ISO | ITGAE (Homo sapiens) | 6480464 | ITGAE protein results in increased susceptibility to Cisplatin | CTD | PMID:16734730 | Itgae | Mouse | copper(II) sulfate | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ITGAE mRNA | CTD | PMID:19549813 | Itgae | Mouse | coumestrol | multiple interactions | ISO | ITGAE (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ITGAE mRNA | CTD | PMID:19167446 | Itgae | Mouse | coumestrol | increases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Coumestrol results in increased expression of ITGAE mRNA | CTD | PMID:19167446 | Itgae | Mouse | cyclosporin A | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ITGAE mRNA | CTD | PMID:25562108 | Itgae | Mouse | cypermethrin | decreases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | cypermethrin results in decreased expression of ITGAE mRNA | CTD | PMID:22528246 | Itgae | Mouse | dexamethasone | increases expression | EXP | | 6480464 | Dexamethasone results in increased expression of ITGAE mRNA | CTD | PMID:21041162 | Itgae | Mouse | Dibutyl phosphate | affects expression | ISO | ITGAE (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of ITGAE mRNA | CTD | PMID:37042841 | Itgae | Mouse | dicrotophos | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of ITGAE mRNA | CTD | PMID:28302478 | Itgae | Mouse | diethylstilbestrol | increases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Diethylstilbestrol results in increased expression of ITGAE mRNA | CTD | PMID:17010207 | Itgae | Mouse | diuron | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Diuron results in decreased expression of ITGAE mRNA | CTD | PMID:35967413 | Itgae | Mouse | elemental selenium | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Selenium results in decreased expression of ITGAE mRNA | CTD | PMID:19244175 | Itgae | Mouse | endosulfan | increases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of ITGAE mRNA | CTD | PMID:29391264 | Itgae | Mouse | Enterolactone | multiple interactions | ISO | ITGAE (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of ITGAE mRNA | CTD | PMID:19167446 | Itgae | Mouse | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of ITGAE mRNA | CTD | PMID:35436446 | Itgae | Mouse | ether | increases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Ether results in increased expression of ITGAE mRNA | CTD | PMID:28717108 | Itgae | Mouse | folpet | decreases expression | EXP | | 6480464 | folpet results in decreased expression of ITGAE mRNA | CTD | PMID:31558096 | Itgae | Mouse | fulvestrant | multiple interactions | ISO | ITGAE (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ITGAE gene | CTD | PMID:31601247 | Itgae | Mouse | gentamycin | decreases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of ITGAE mRNA | CTD | PMID:33387578 | Itgae | Mouse | glyphosate | increases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Glyphosate results in increased expression of ITGAE mRNA | CTD | PMID:17984146 | Itgae | Mouse | indometacin | increases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Indomethacin results in increased expression of ITGAE mRNA | CTD | PMID:16771604 | Itgae | Mouse | irinotecan | increases response to substance | ISO | ITGAE (Homo sapiens) | 6480464 | ITGAE protein results in increased susceptibility to Irinotecan | CTD | PMID:16734730 | Itgae | Mouse | isoflurane | increases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Isoflurane results in increased expression of ITGAE mRNA | CTD | PMID:28717108 | Itgae | Mouse | methapyrilene | decreases methylation | ISO | ITGAE (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of ITGAE intron | CTD | PMID:30157460 | Itgae | Mouse | methyl methanesulfonate | increases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of ITGAE mRNA | CTD | PMID:23649840 | Itgae | Mouse | pentobarbital | increases expression | ISO | Itgae (Rattus norvegicus) | 6480464 | Pentobarbital results in increased expression of ITGAE mRNA | CTD | PMID:28717108 | Itgae | Mouse | picoxystrobin | increases expression | ISO | ITGAE (Homo sapiens) | 6480464 | picoxystrobin results in increased expression of ITGAE mRNA | CTD | PMID:33512557 | Itgae | Mouse | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of ITGAE mRNA | CTD | PMID:17426115 | Itgae | Mouse | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ITGAE mRNA | CTD | PMID:20813756 | Itgae | Mouse | potassium dichromate | decreases expression | EXP | | 6480464 | Potassium Dichromate results in decreased expression of ITGAE mRNA | CTD | PMID:23608068 | Itgae | Mouse | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of ITGAE mRNA | CTD | PMID:22698814 | Itgae | Mouse | pyrimidifen | increases expression | ISO | ITGAE (Homo sapiens) | 6480464 | pyrimidifen results in increased expression of ITGAE mRNA | CTD | PMID:33512557 | Itgae | Mouse | selenium atom | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | Selenium results in decreased expression of ITGAE mRNA | CTD | PMID:19244175 | Itgae | Mouse | silver atom | increases expression | EXP | | 6480464 | Silver results in increased expression of ITGAE mRNA | CTD | PMID:27131904 | Itgae | Mouse | silver(0) | increases expression | EXP | | 6480464 | Silver results in increased expression of ITGAE mRNA | CTD | PMID:27131904 | Itgae | Mouse | sodium arsenite | affects methylation | ISO | ITGAE (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of ITGAE gene | CTD | PMID:28589171 | Itgae | Mouse | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of ITGAE mRNA | CTD | PMID:37682722 | Itgae | Mouse | sodium arsenite | affects expression | ISO | ITGAE (Homo sapiens) | 6480464 | sodium arsenite affects the expression of ITGAE mRNA | CTD | PMID:34032870 | Itgae | Mouse | sodium arsenite | decreases expression | ISO | ITGAE (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ITGAE mRNA | CTD | PMID:38568856 | Itgae | Mouse | sodium dichromate | decreases expression | EXP | | 6480464 | sodium bichromate results in decreased expression of ITGAE mRNA | CTD | PMID:31558096 | Itgae | Mouse | tetracycline | increases expression | EXP | | 6480464 | Tetracycline results in increased expression of ITGAE mRNA | CTD | PMID:16917069 | Itgae | Mouse | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of ITGAE mRNA | CTD | PMID:21259345 and PMID:35295148 | Itgae | Mouse | toluene 2,4-diisocyanate | increases expression | EXP | | 6480464 | Toluene 2 and 4-Diisocyanate results in increased expression of ITGAE protein | CTD | PMID:27103660 | Itgae | Mouse | triphenyl phosphate | affects expression | ISO | ITGAE (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ITGAE mRNA | CTD | PMID:37042841 | Itgae | Mouse | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of ITGAE mRNA | CTD | PMID:33045310 | Itgae | Mouse | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ITGAE mRNA | CTD | PMID:17963808 | Itgae | Mouse | valproic acid | increases methylation | ISO | ITGAE (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ITGAE gene | CTD | PMID:29154799 | |