(+)-dexrazoxane multiple interactions EXP 6480464 Dexrazoxane inhibits the reaction [Idarubicin results in increased expression of CDKN1A mRNA] CTD PMID:28973540 (+)-schisandrin B multiple interactions ISO RGD:69328 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of CDKN1A mRNA] CTD PMID:31150632 (+)-Tetrandrine increases expression ISO RGD:735341 6480464 tetrandrine results in increased expression of CDKN1A CTD PMID:19840446 (+)-Tetrandrine multiple interactions ISO RGD:735341 6480464 [sodium arsenite co-treated with tetrandrine] affects the expression of CDKN1A protein CTD PMID:30123091 (+)-Tetrandrine affects expression ISO RGD:735341 6480464 tetrandrine affects the expression of CDKN1A protein CTD PMID:30123091 (-)-alpha-phellandrene increases expression ISO RGD:735341 6480464 alpha phellandrene results in increased expression of CDKN1A mRNA CTD PMID:25075043 (-)-citrinin increases expression EXP 6480464 Citrinin results in increased expression of CDKN1A protein CTD PMID:21622943 (-)-citrinin increases expression ISO RGD:735341 6480464 Citrinin results in increased expression of CDKN1A protein CTD PMID:20929984 (-)-demecolcine increases expression ISO RGD:735341 6480464 Demecolcine results in increased expression of CDKN1A mRNA CTD PMID:23649840 (-)-demecolcine decreases expression ISO RGD:735341 6480464 Demecolcine results in decreased expression of CDKN1A mRNA CTD PMID:24211769 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:735341 6480464 [epigallocatechin gallate co-treated with leptomycin B] results in increased expression of CDKN1A mRNA more ... CTD PMID:12628509 , PMID:25922640 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 [epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9 more ... CTD PMID:23717041 (-)-epigallocatechin 3-gallate increases expression ISO RGD:735341 6480464 epigallocatechin gallate results in increased expression of CDKN1A protein CTD PMID:15764647 , PMID:32512070 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:735341 6480464 epigallocatechin gallate results in decreased expression of CDKN1A mRNA CTD PMID:18851785 (-)-epigallocatechin 3-gallate increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to epigallocatechin gallate CTD PMID:15764647 (-)-noscapine multiple interactions ISO RGD:735341 6480464 Noscapine promotes the reaction [Cisplatin results in increased expression of CDKN1A protein] CTD PMID:20674069 (-)-noscapine increases expression ISO RGD:735341 6480464 Noscapine results in increased expression of CDKN1A protein CTD PMID:20674069 (1S)-bornane-2,3-dione multiple interactions ISO RGD:735341 6480464 Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of CDKN1A protein] CTD PMID:26658076 (1S)-bornane-2,3-dione increases expression ISO RGD:735341 6480464 camphorquinone results in increased expression of CDKN1A mRNA, camphorquinone results in increased expression of CDKN1A protein CTD PMID:26658076 (aminomethyl)phosphonic acid increases expression ISO RGD:735341 6480464 1-aminomethylphosphonic acid results in increased expression of CDKN1A protein CTD PMID:23983455 (aminomethyl)phosphonic acid multiple interactions ISO RGD:735341 6480464 [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased expression of CDKN1A protein CTD PMID:26006246 (aminooxy)acetic acid multiple interactions ISO RGD:735341 6480464 [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein CTD PMID:25321483 (R,R,R)-alpha-tocopherol multiple interactions ISO RGD:69328 6480464 alpha-Tocopherol inhibits the reaction [Acrylonitrile results in increased expression of CDKN1A mRNA] CTD PMID:26332274 (R,R,R)-alpha-tocopherol decreases expression ISO RGD:69328 6480464 alpha-Tocopherol results in decreased expression of CDKN1A mRNA CTD PMID:26332274 (S)-(-)-perillyl alcohol increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to perillyl alcohol CTD PMID:17138864 (S)-(-)-perillyl alcohol multiple interactions ISO RGD:735341 6480464 perillyl alcohol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein] CTD PMID:17138864 (S)-(-)-perillyl alcohol increases expression ISO RGD:735341 6480464 perillyl alcohol results in increased expression of CDKN1A protein CTD PMID:17138864 (S)-colchicine increases expression ISO RGD:69328 6480464 Colchicine results in increased expression of CDKN1A mRNA CTD PMID:20624997 (S)-colchicine increases expression ISO RGD:735341 6480464 Colchicine results in increased expression of CDKN1A protein CTD PMID:27358234 (S)-colchicine decreases expression ISO RGD:735341 6480464 Colchicine results in decreased expression of CDKN1A mRNA CTD PMID:24211769 (S)-naringenin increases expression ISO RGD:735341 6480464 naringenin metabolite results in increased expression of CDKN1A mRNA, naringenin results in increased expression of CDKN1A mRNA CTD PMID:30153467 , PMID:36235125 (S)-naringenin multiple interactions ISO RGD:735341 6480464 [naringenin co-treated with bisphenol A] results in increased expression of CDKN1A mRNA more ... CTD PMID:30153467 , PMID:36235125 (S)-nicotine decreases expression ISO RGD:735341 6480464 Nicotine results in decreased expression of CDKN1A protein CTD PMID:18805435 , PMID:30272249 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of CDKN1A mRNA, Nicotine results in increased expression of CDKN1A protein CTD PMID:31507073 , PMID:32473187 (S)-nicotine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN1A mRNA] more ... CTD PMID:32473187 (S)-nicotine increases expression ISO RGD:735341 6480464 Nicotine results in increased expression of CDKN1A protein CTD PMID:16011614 , PMID:20727180 (S)-nicotine multiple interactions ISO RGD:735341 6480464 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in decreased expression of CDKN1A protein] more ... CTD PMID:16601104 , PMID:18805435 (Z)-3-butylidenephthalide decreases expression ISO RGD:69328 6480464 butylidenephthalide results in decreased expression of CDKN1A protein CTD PMID:16987298 (Z)-3-butylidenephthalide increases expression ISO RGD:735341 6480464 butylidenephthalide results in increased expression of CDKN1A protein CTD PMID:16987298 , PMID:23770345 (Z)-ligustilide increases expression ISO RGD:735341 6480464 ligustilide results in increased expression of CDKN1A protein CTD PMID:31765699 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane increases expression EXP 6480464 2 more ... CTD PMID:20826375 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o, p'-DDT affects the expression of CDKN1A mRNA CTD PMID:18925944 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expression ISO RGD:69328 6480464 o, p'-DDT results in decreased expression of CDKN1A mRNA CTD PMID:23209616 1,1-dichloroethene increases expression EXP 6480464 vinylidene chloride results in increased expression of CDKN1A mRNA CTD PMID:26682919 1,2,4-trimethylbenzene increases expression ISO RGD:69328 6480464 pseudocumene results in increased expression of CDKN1A protein CTD PMID:17337753 1,2-dichloroethane affects expression EXP 6480464 ethylene dichloride affects the expression of CDKN1A mRNA CTD PMID:28960355 1,2-dimethylhydrazine decreases expression EXP 6480464 1, 2-Dimethylhydrazine results in decreased expression of CDKN1A mRNA CTD PMID:26388957 1,2-dimethylhydrazine multiple interactions EXP 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CDKN1A mRNA CTD PMID:22206623 1,3-dinitrobenzene increases expression EXP 6480464 3-dinitrobenzene results in increased expression of CDKN1A protein CTD PMID:19477251 1,3-thiazolidine-2,4-dione increases expression ISO RGD:735341 6480464 2, 4-thiazolidinedione results in increased expression of CDKN1A protein CTD PMID:15916743 1,4-benzoquinone increases expression ISO RGD:735341 6480464 quinone results in increased expression of CDKN1A mRNA CTD PMID:14976336 1,4-benzoquinone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [quinone analog results in increased expression of CDKN1A protein] more ... CTD PMID:33961949 1,4-benzoquinone increases expression EXP 6480464 quinone analog results in increased expression of CDKN1A protein CTD PMID:33961949 1,4-phenylenediamine increases expression ISO RGD:735341 6480464 4-phenylenediamine results in increased expression of CDKN1A mRNA CTD PMID:16314067 1-chloro-2,4-dinitrobenzene increases expression ISO RGD:735341 6480464 Dinitrochlorobenzene results in increased expression of CDKN1A mRNA CTD PMID:16314067 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of CDKN1A mRNA CTD PMID:21404309 1-methylphenanthrene multiple interactions ISO RGD:735341 6480464 [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CDKN1A mRNA CTD PMID:17690111 1-naphthyl isothiocyanate increases expression ISO RGD:69328 6480464 1-Naphthylisothiocyanate results in increased expression of CDKN1A mRNA, 1-Naphthylisothiocyanate results in increased expression of CDKN1A protein CTD PMID:20551477 more ... 1-nitropropane decreases expression ISO RGD:69328 6480464 1-nitropropane results in decreased expression of CDKN1A mRNA CTD PMID:17070881 1-nitropyrene increases expression ISO RGD:735341 6480464 1-nitropyrene results in increased expression of CDKN1A mRNA, 1-nitropyrene results in increased expression of CDKN1A protein CTD PMID:21540303 , PMID:22044530 1-nitropyrene multiple interactions ISO RGD:735341 6480464 pifithrin results in decreased susceptibility to [1-nitropyrene results in increased expression of CDKN1A protein], Tetrachlorodibenzodioxin results in decreased susceptibility to [1-nitropyrene results in increased expression of CDKN1A protein] CTD PMID:22044530 15-deoxy-Delta(12,14)-prostaglandin J2 increases expression ISO RGD:735341 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 results in increased expression of CDKN1A CTD PMID:15254749 15-deoxy-Delta(12,14)-prostaglandin J2 decreases expression ISO RGD:735341 6480464 15-deoxy-delta(12, 14)-prostaglandin J2 results in decreased expression of CDKN1A protein CTD PMID:15729575 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of CDKN1A mRNA CTD PMID:14976129 17alpha-ethynylestradiol affects expression ISO RGD:69328 6480464 Ethinyl Estradiol affects the expression of CDKN1A mRNA CTD PMID:26865667 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of CDKN1A mRNA CTD PMID:17555576 , PMID:17942748 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDKN1A mRNA CTD PMID:17942748 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of CDKN1A mRNA CTD PMID:17640349 more ... 17beta-estradiol decreases expression ISO RGD:69328 6480464 Estradiol results in decreased expression of CDKN1A mRNA CTD PMID:35192832 17beta-estradiol affects expression ISO RGD:69328 6480464 Estradiol affects the expression of CDKN1A mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO RGD:69328 6480464 [bisphenol A co-treated with Estradiol] results in increased expression of CDKN1A mRNA CTD PMID:26496021 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of CDKN1A mRNA CTD PMID:23684557 17beta-estradiol increases expression ISO RGD:735341 6480464 Estradiol results in increased expression of CDKN1A mRNA, Estradiol results in increased expression of CDKN1A protein CTD PMID:12154049 more ... 17beta-estradiol decreases expression ISO RGD:735341 6480464 Estradiol results in decreased expression of CDKN1A more ... CTD PMID:12473173 more ... 17beta-estradiol multiple interactions EXP 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of CDKN1A mRNA] more ... CTD PMID:16977382 more ... 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of CDKN1A mRNA CTD PMID:15598610 17beta-estradiol affects expression ISO RGD:735341 6480464 Estradiol affects the expression of CDKN1A mRNA CTD PMID:11896290 , PMID:24481588 17beta-estradiol multiple interactions ISO RGD:735341 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CDKN1A mRNA more ... CTD PMID:12473173 more ... 17beta-hydroxy-5alpha-androstan-3-one decreases expression ISO RGD:735341 6480464 Dihydrotestosterone results in decreased expression of CDKN1A protein CTD PMID:15322241 , PMID:26804032 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO RGD:735341 6480464 Dihydrotestosterone inhibits the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein] CTD PMID:27132804 19-Nor-17alpha-pregn-5(10)-en-20-yne-3alpha,17beta-diol increases expression ISO RGD:69328 6480464 17alpha-ethynylestr-5(10)-ene-3alpha, 17beta-diol results in increased expression of CDKN1A protein CTD PMID:16019103 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one increases expression ISO RGD:735341 6480464 1H-(1 more ... CTD PMID:16288207 1H-pyrazole increases expression EXP 6480464 pyrazole results in increased expression of CDKN1A mRNA CTD PMID:17945193 2'-deoxyadenosine decreases expression ISO RGD:735341 6480464 2'-deoxyadenosine results in decreased expression of CDKN1A mRNA CTD PMID:24211769 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:69328 6480464 2 more ... CTD PMID:33581290 2,2',4,4'-Tetrabromodiphenyl ether affects expression EXP 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:735341 6480464 2 more ... CTD PMID:26988655 2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one increases expression ISO RGD:735341 6480464 2 more ... CTD PMID:21109480 , PMID:21647879 2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one multiple interactions ISO RGD:735341 6480464 Cisplatin promotes the reaction [2 more ... CTD PMID:21109480 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735341 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1A protein] more ... CTD PMID:12473173 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CDKN1A mRNA CTD PMID:18343893 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of CDKN1A mRNA CTD PMID:12167310 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:69328 6480464 Tetrachlorodibenzodioxin results in decreased expression of CDKN1A mRNA CTD PMID:20959002 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735341 6480464 Tetrachlorodibenzodioxin results in increased expression of CDKN1A mRNA, Tetrachlorodibenzodioxin results in increased expression of CDKN1A protein CTD PMID:12203118 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:69328 6480464 Tetrachlorodibenzodioxin results in increased expression of CDKN1A mRNA CTD PMID:20566336 , PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:69328 6480464 AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1A mRNA], Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased expression of CDKN1A protein] CTD PMID:15459018 , PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CDKN1A mRNA CTD PMID:15667827 , PMID:17586704 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDKN1A mRNA more ... CTD PMID:17942748 more ... 2,3,7,8-tetrachlorodibenzodioxine affects binding EXP 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which binds to CDKN1A promoter CTD PMID:14718646 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:735341 6480464 Tetrachlorodibenzodioxin results in decreased expression of CDKN1A mRNA, Tetrachlorodibenzodioxin results in decreased expression of CDKN1A protein CTD PMID:15322241 more ... 2,3,7,8-Tetrachlorodibenzofuran affects expression EXP 6480464 2 more ... CTD PMID:18343893 , PMID:20702594 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO RGD:69328 6480464 2 more ... CTD PMID:32109520 2,4-diaminotoluene increases expression EXP 6480464 2, 4-diaminotoluene results in increased expression of CDKN1A mRNA CTD PMID:20713471 2,4-diaminotoluene increases expression ISO RGD:69328 6480464 2, 4-diaminotoluene results in increased expression of CDKN1A mRNA CTD PMID:17070881 2,4-dibromophenol increases expression EXP 6480464 2, 4-dibromophenol metabolite results in increased expression of CDKN1A protein CTD PMID:33961949 2,4-dibromophenol multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:33961949 2,4-Dihydroxybenzophenone decreases expression ISO RGD:735341 6480464 2, 4-dihydroxybenzophenone results in decreased expression of CDKN1A protein CTD PMID:23328252 2,4-dinitrotoluene affects expression ISO RGD:69328 6480464 2, 4-dinitrotoluene affects the expression of CDKN1A mRNA CTD PMID:21346803 2,5-bis(aziridin-1-yl)-1,4-benzoquinone multiple interactions ISO RGD:735341 6480464 Acetylcysteine inhibits the reaction [ethylenimine quinone results in increased expression of CDKN1A mRNA] CTD PMID:8943236 2,5-bis(aziridin-1-yl)-1,4-benzoquinone increases expression ISO RGD:735341 6480464 ethylenimine quinone results in increased expression of CDKN1A mRNA, ethylenimine quinone results in increased expression of CDKN1A protein CTD PMID:8943236 more ... 2,6-diaminotoluene increases expression ISO RGD:69328 6480464 2, 6-diaminotoluene results in increased expression of CDKN1A mRNA CTD PMID:17070881 2,6-dichloroindophenol multiple interactions ISO RGD:735341 6480464 [2 more ... CTD PMID:21034357 2,6-dinitrotoluene affects expression ISO RGD:69328 6480464 2, 6-dinitrotoluene affects the expression of CDKN1A mRNA CTD PMID:21346803 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one increases expression ISO RGD:69328 6480464 Praziquantel results in increased expression of CDKN1A mRNA CTD PMID:21813463 2-acetamidofluorene multiple interactions ISO RGD:69328 6480464 2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein] more ... CTD PMID:11003613 more ... 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of CDKN1A mRNA CTD PMID:21607683 2-acetamidofluorene multiple interactions EXP 6480464 TRP53 protein modified form affects the reaction [2-Acetylaminofluorene affects the expression of CDKN1A mRNA] CTD PMID:17317680 2-acetamidofluorene increases expression ISO RGD:69328 6480464 2-Acetylaminofluorene results in increased expression of CDKN1A mRNA, 2-Acetylaminofluorene results in increased expression of CDKN1A protein CTD PMID:10708481 more ... 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:69328 6480464 Glucosamine results in increased expression of CDKN1A protein CTD PMID:15654767 2-amino-2-deoxy-D-glucopyranose increases expression EXP 6480464 Glucosamine results in increased expression of CDKN1A mRNA CTD PMID:17178593 2-amino-4,6-dinitrotoluene affects expression ISO RGD:69328 6480464 2-amino-4, 6-dinitrotoluene affects the expression of CDKN1A mRNA CTD PMID:21346803 2-butoxyethanol increases expression EXP 6480464 n-butoxyethanol results in increased expression of CDKN1A mRNA CTD PMID:19812364 2-deoxy-D-glucose multiple interactions ISO RGD:735341 6480464 [demycarosyl-3D-digitoxosylmithramycin SK co-treated with Deoxyglucose] results in increased expression of CDKN1A mRNA CTD PMID:26079942 2-methylcholine affects expression ISO RGD:735341 6480464 beta-methylcholine affects the expression of CDKN1A mRNA CTD PMID:21179406 2-nitro-p-phenylenediamine decreases expression ISO RGD:69328 6480464 2-nitro-4-phenylenediamine results in decreased expression of CDKN1A mRNA CTD PMID:17070881 2-nitrofluorene increases expression ISO RGD:69328 6480464 2-nitrofluorene results in increased expression of CDKN1A mRNA CTD PMID:14600272 more ... 2-nitropropane increases expression ISO RGD:69328 6480464 2-nitropropane results in increased expression of CDKN1A mRNA CTD PMID:17070881 2-nitrotoluene increases expression EXP 6480464 2-nitrotoluene results in increased expression of CDKN1A mRNA CTD PMID:15618236 2-nitrotoluene decreases expression ISO RGD:69328 6480464 2-nitrotoluene results in decreased expression of CDKN1A mRNA CTD PMID:16460773 2-pyridylethylamine multiple interactions ISO RGD:735341 6480464 [Copper binds to Isatin binds to 2-(2-aminoethyl)pyridine] which results in increased expression of CDKN1A protein CTD PMID:17327230 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO RGD:735341 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in increased expression of CDKN1A protein] CTD PMID:18625202 20-hydroxypregn-4-en-3-one increases expression ISO RGD:735341 6480464 3-hydroxypregn-4-en-20-one results in increased expression of CDKN1A mRNA CTD PMID:19931389 3',4',5-trihydroxy-3,7-dimethoxyflavone increases expression ISO RGD:735341 6480464 5 more ... CTD PMID:21229608 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions EXP 6480464 1, 3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CDKN1A protein] CTD PMID:17035936 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression ISO RGD:69328 6480464 Puromycin Aminonucleoside results in increased expression of CDKN1A protein CTD PMID:17035936 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions ISO RGD:69328 6480464 1, 3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased expression of CDKN1A protein] CTD PMID:17035936 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression EXP 6480464 Puromycin Aminonucleoside results in increased expression of CDKN1A protein CTD PMID:17035936 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:735341 6480464 3 more ... CTD PMID:20840854 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:69328 6480464 3 more ... CTD PMID:23196670 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:69328 6480464 3 more ... CTD PMID:20959002 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:735341 6480464 3 more ... CTD PMID:20840854 3,3',5,5'-tetrabromobisphenol A decreases expression ISO RGD:69328 6480464 tetrabromobisphenol A results in decreased expression of CDKN1A mRNA CTD PMID:27914987 3,3',5,5'-tetraiodothyroacetic acid multiple interactions ISO RGD:735341 6480464 heteronemin inhibits the reaction [tetraiodothyroacetic acid results in decreased expression of CDKN1A mRNA] more ... CTD PMID:35151786 3,3',5,5'-tetraiodothyroacetic acid decreases expression ISO RGD:735341 6480464 tetraiodothyroacetic acid results in decreased expression of CDKN1A mRNA CTD PMID:35151786 3,3',5,5'-tetraiodothyroacetic acid increases expression ISO RGD:735341 6480464 tetraiodothyroacetic acid results in increased expression of CDKN1A mRNA CTD PMID:35151786 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:735341 6480464 [Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in increased expression of CDKN1A mRNA more ... CTD PMID:14761676 , PMID:22383522 3,3',5-triiodo-L-thyronine increases expression ISO RGD:735341 6480464 Triiodothyronine results in increased expression of CDKN1A mRNA CTD PMID:14761676 3,3'-diindolylmethane multiple interactions ISO RGD:735341 6480464 3, 3'-diindolylmethane promotes the reaction [CDK2 protein binds to CDKN1A protein] CTD PMID:15611077 3,3'-diindolylmethane increases expression ISO RGD:735341 6480464 3 more ... CTD PMID:12203118 more ... 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine increases expression ISO RGD:735341 6480464 3 more ... CTD PMID:23810796 3,4-dihydroxybenzoic acid increases expression ISO RGD:69328 6480464 protocatechuic acid results in increased expression of CDKN1A protein CTD PMID:16227210 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of CDKN1A mRNA CTD PMID:20188158 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of CDKN1A mRNA CTD PMID:26251327 3-aminobenzamide increases expression ISO RGD:735341 6480464 3-aminobenzamide results in increased expression of CDKN1A mRNA CTD PMID:15670817 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [Acrylamide co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CDKN1A protein CTD PMID:30409764 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine decreases expression EXP 6480464 2-amino-3-methylimidazo(4, 5-f)quinoline results in decreased expression of CDKN1A protein CTD PMID:22094457 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases expression ISO RGD:735341 6480464 2-amino-3-methylimidazo(4, 5-f)quinoline results in increased expression of CDKN1A mRNA CTD PMID:31542801 3-methyladenine multiple interactions ISO RGD:735341 6480464 3-methyladenine inhibits the reaction [Caffeine inhibits the reaction [2 more ... CTD PMID:22927544 , PMID:30555576 3-methyladenine multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Caffeine inhibits the reaction [2, 2'-azobis(2-amidinopropane) results in increased expression of CDKN1A protein]] CTD PMID:30555576 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of CDKN1A mRNA CTD PMID:15882963 3-methylcholanthrene increases expression ISO RGD:735341 6480464 Methylcholanthrene results in increased expression of CDKN1A protein CTD PMID:18022818 3-methylcholanthrene increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to Methylcholanthrene CTD PMID:18022818 3-methylcholanthrene multiple interactions ISO RGD:735341 6480464 Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein], resveratrol inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein] CTD PMID:18022818 3-methylcholanthrene multiple interactions EXP 6480464 SB 203580 inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A mRNA] CTD PMID:15882963 3-Nitrobenzanthrone increases expression EXP 6480464 3-nitrobenzanthrone results in increased expression of CDKN1A protein CTD PMID:25230394 3-phenylprop-2-enal increases expression ISO RGD:735341 6480464 cinnamaldehyde results in increased expression of CDKN1A mRNA, cinnamaldehyde results in increased expression of CDKN1A protein CTD PMID:19000754 4,4'-diaminodiphenylmethane increases expression ISO RGD:69328 6480464 4, 4'-diaminodiphenylmethane results in increased expression of CDKN1A mRNA CTD PMID:25380136 4,4'-sulfonyldiphenol decreases expression ISO RGD:735341 6480464 bis(4-hydroxyphenyl)sulfone results in decreased expression of CDKN1A mRNA CTD PMID:30684532 4,4'-sulfonyldiphenol multiple interactions ISO RGD:69328 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CDKN1A mRNA CTD PMID:36041667 4,4'-sulfonyldiphenol decreases methylation ISO RGD:735341 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of CDKN1A gene CTD PMID:31601247 4,4'-sulfonyldiphenol increases expression ISO RGD:735341 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of CDKN1A mRNA, bis(4-hydroxyphenyl)sulfone results in increased expression of CDKN1A protein CTD PMID:30292839 , PMID:36565802 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO RGD:735341 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A protein CTD PMID:20421341 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO RGD:69328 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDKN1A mRNA CTD PMID:14600272 more ... 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1A mRNA CTD PMID:21167638 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases expression ISO RGD:735341 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1A protein CTD PMID:18805435 , PMID:30236600 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:735341 6480464 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CDKN1A protein] more ... CTD PMID:18508827 , PMID:18805435 4-acetylaminofluorene decreases expression ISO RGD:69328 6480464 4-acetylaminofluorene results in decreased expression of CDKN1A mRNA CTD PMID:17070881 4-hydroperoxycyclophosphamide increases expression ISO RGD:735341 6480464 perfosfamide results in increased expression of CDKN1A CTD PMID:18034189 4-hydroperoxycyclophosphamide increases expression EXP 6480464 perfosfamide results in increased expression of CDKN1A mRNA, perfosfamide results in increased expression of CDKN1A protein CTD PMID:17068108 4-hydroxy-TEMPO increases expression ISO RGD:735341 6480464 tempol results in increased expression of CDKN1A protein CTD PMID:15601469 4-hydroxy-TEMPO multiple interactions ISO RGD:735341 6480464 tempol promotes the reaction [CDKN1A protein results in increased susceptibility to Doxorubicin] CTD PMID:15601469 4-hydroxynon-2-enal increases expression ISO RGD:735341 6480464 4-hydroxy-2-nonenal results in increased expression of CDKN1A protein CTD PMID:15607904 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of CDKN1A mRNA CTD PMID:28973697 4-hydroxyphenyl retinamide increases expression ISO RGD:735341 6480464 Fenretinide results in increased expression of CDKN1A protein CTD PMID:16540676 , PMID:16570282 4-nitro-1,2-phenylenediamine decreases expression ISO RGD:69328 6480464 1, 2-diamino-4-nitrobenzene results in decreased expression of CDKN1A mRNA CTD PMID:17070881 4-nitrophenol increases expression EXP 6480464 4-nitrophenol results in increased expression of CDKN1A mRNA CTD PMID:34673133 4-nonylphenol increases expression ISO RGD:69328 6480464 4-nonylphenol results in increased expression of CDKN1A protein CTD PMID:26804764 4-nonylphenol decreases expression ISO RGD:735341 6480464 4-nonylphenol results in decreased expression of CDKN1A protein CTD PMID:26804032 4-phenylbutyric acid multiple interactions ISO RGD:735341 6480464 [4-phenylbutyric acid co-treated with decitabine] results in increased expression of CDKN1A mRNA CTD PMID:17210717 4-phenylbutyric acid increases expression ISO RGD:735341 6480464 4-phenylbutyric acid results in increased expression of CDKN1A protein CTD PMID:23770000 4-tert-Octylphenol decreases expression ISO RGD:735341 6480464 4-tert-octylphenol results in decreased expression of CDKN1A mRNA CTD PMID:24684733 5,6,7,8-tetrahydrobiopterin multiple interactions ISO RGD:735341 6480464 sapropterin inhibits the reaction [Methotrexate results in increased expression of CDKN1A protein] CTD PMID:22183962 5,7-dihydroxy-4'-methoxyflavone increases expression ISO RGD:735341 6480464 acacetin results in increased expression of CDKN1A protein CTD PMID:36740148 5-(2-chloroethyl)-4-methylthiazole multiple interactions ISO RGD:69328 6480464 Chlormethiazole inhibits the reaction [Acetaminophen results in increased degradation of CDKN1A protein] CTD PMID:16330492 5-aza-2'-deoxycytidine decreases methylation ISO RGD:69328 6480464 Decitabine results in decreased methylation of CDKN1A promoter CTD PMID:30649504 5-aza-2'-deoxycytidine affects expression ISO RGD:735341 6480464 [Decitabine affects the expression of DNMT3B protein] which affects the expression of CDKN1A mRNA, Decitabine affects the expression of CDKN1A mRNA CTD PMID:18544619 , PMID:23300844 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of CDKN1A mRNA CTD PMID:25549359 , PMID:27915011 5-aza-2'-deoxycytidine multiple interactions ISO RGD:735341 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Decitabine results in increased expression of CDKN1A protein] more ... CTD PMID:14722112 more ... 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 [Decitabine co-treated with Valproic Acid] results in increased expression of CDKN1A mRNA CTD PMID:19155313 5-aza-2'-deoxycytidine increases expression ISO RGD:735341 6480464 Decitabine results in increased expression of CDKN1A more ... CTD PMID:12859993 more ... 5-aza-2'-deoxycytidine decreases methylation ISO RGD:735341 6480464 Decitabine results in decreased methylation of CDKN1A gene, Decitabine results in decreased methylation of CDKN1A promoter CTD PMID:19234609 more ... 5-azacytidine multiple interactions ISO RGD:69328 6480464 [Azacitidine co-treated with entinostat] results in increased expression of CDKN1A mRNA, Azacitidine inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein] CTD PMID:21224363 , PMID:25015661 5-azacytidine increases expression ISO RGD:69328 6480464 Azacitidine results in increased expression of CDKN1A mRNA CTD PMID:21224363 5-azacytidine multiple interactions ISO RGD:735341 6480464 [metacept-1 co-treated with Azacitidine] results in increased expression of CDKN1A CTD PMID:19148494 5-azacytidine increases expression ISO RGD:735341 6480464 Azacitidine analog results in increased expression of CDKN1A protein, Azacitidine results in increased expression of CDKN1A mRNA CTD PMID:18324645 , PMID:20823114 5-bromo-2'-deoxyuridine multiple interactions EXP 6480464 [Bromodeoxyuridine co-treated with furan] results in increased expression of CDKN1A mRNA CTD PMID:24910943 5-chloro-7-iodoquinolin-8-ol increases expression ISO RGD:735341 6480464 Clioquinol results in increased expression of CDKN1A mRNA CTD PMID:22627294 5-fluorouracil affects response to substance ISO RGD:735341 6480464 CDKN1A affects the susceptibility to Fluorouracil, CDKN1A protein affects the susceptibility to Fluorouracil CTD PMID:15067352 , PMID:15331170 5-fluorouracil multiple interactions EXP 6480464 Fluorouracil promotes the reaction [Luteolin results in increased expression of CDKN1A protein], Luteolin promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein] CTD PMID:31288002 5-fluorouracil increases expression EXP 6480464 Fluorouracil results in increased expression of CDKN1A mRNA, Fluorouracil results in increased expression of CDKN1A protein CTD PMID:16949053 , PMID:31288002 5-fluorouracil increases expression ISO RGD:735341 6480464 Fluorouracil results in increased expression of CDKN1A more ... CTD PMID:14646558 more ... 5-fluorouracil decreases degradation ISO RGD:735341 6480464 Fluorouracil results in decreased degradation of CDKN1A protein CTD PMID:15625077 5-fluorouracil decreases expression ISO RGD:735341 6480464 Fluorouracil results in decreased expression of CDKN1A protein CTD PMID:15754201 5-fluorouracil multiple interactions ISO RGD:735341 6480464 [Fluorouracil co-treated with Genistein] results in increased expression of CDKN1A mRNA more ... CTD PMID:15016801 more ... 5-fluorouracil decreases response to substance ISO RGD:735341 6480464 CDKN1A protein results in decreased susceptibility to Fluorouracil CTD PMID:16686938 5-fluorouracil increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to Fluorouracil CTD PMID:15375580 5-formyltetrahydrofolic acid multiple interactions ISO RGD:735341 6480464 [Leucovorin co-treated with Fluorouracil] results in increased expression of CDKN1A mRNA CTD PMID:15342418 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases expression ISO RGD:735341 6480464 Omeprazole results in increased expression of CDKN1A protein CTD PMID:27358234 5-methoxypsoralen multiple interactions ISO RGD:735341 6480464 pifithrin inhibits the reaction [5-Methoxypsoralen results in increased expression of CDKN1A protein] CTD PMID:30576070 5-methoxypsoralen increases expression ISO RGD:735341 6480464 5-Methoxypsoralen results in increased expression of CDKN1A protein CTD PMID:30576070 6-O-methylguanine multiple interactions ISO RGD:735341 6480464 [O(6)-benzylguanine co-treated with O-(6)-methylguanine] results in decreased expression of CDKN1A mRNA, [O(6)-benzylguanine co-treated with O-(6)-methylguanine] results in decreased expression of CDKN1A protein CTD PMID:29666243 6-oxocampestanol increases expression ISO RGD:735341 6480464 6-oxocampestanol results in increased expression of CDKN1A protein CTD PMID:32001316 6-propyl-2-thiouracil decreases expression ISO RGD:69328 6480464 Propylthiouracil results in decreased expression of CDKN1A mRNA CTD PMID:24780913 , PMID:25825206 6-propyl-2-thiouracil increases expression ISO RGD:69328 6480464 Propylthiouracil results in increased expression of CDKN1A mRNA CTD PMID:30047161 7,12-dimethyltetraphene multiple interactions EXP 6480464 [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 more ... CTD PMID:20043298 more ... 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:25478867 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:20043298 more ... 7,12-dimethyltetraphene increases expression ISO RGD:735341 6480464 9 more ... CTD PMID:21527772 8-Br-cAMP decreases expression ISO RGD:735341 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDKN1A mRNA CTD PMID:22079614 9-cis-retinoic acid decreases expression ISO RGD:735341 6480464 Alitretinoin results in decreased expression of CDKN1A protein CTD PMID:16340750 acetaldehyde affects expression ISO RGD:735341 6480464 Acetaldehyde affects the expression of CDKN1A mRNA CTD PMID:29110037 acetamide increases expression ISO RGD:69328 6480464 acetamide results in increased expression of CDKN1A mRNA CTD PMID:31881176 acetylsalicylic acid multiple interactions ISO RGD:735341 6480464 Aspirin inhibits the reaction [Camptothecin results in increased expression of CDKN1A protein] more ... CTD PMID:19212664 more ... acetylsalicylic acid decreases expression ISO RGD:735341 6480464 Aspirin results in decreased expression of CDKN1A mRNA CTD PMID:20457246 acetylsalicylic acid increases expression ISO RGD:735341 6480464 Aspirin results in increased expression of CDKN1A mRNA, Aspirin results in increased expression of CDKN1A protein CTD PMID:14976132 , PMID:19908241 acetylsalicylic acid affects expression ISO RGD:735341 6480464 Aspirin affects the expression of CDKN1A protein CTD PMID:19212664 acetylsalicylic acid decreases activity ISO RGD:735341 6480464 Aspirin results in decreased activity of CDKN1A protein CTD PMID:15190207 acrolein multiple interactions ISO RGD:735341 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CDKN1A mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of CDKN1A mRNA CTD PMID:32699268 acrolein increases expression ISO RGD:735341 6480464 Acrolein results in increased expression of CDKN1A protein CTD PMID:34958888 acrylamide increases expression ISO RGD:735341 6480464 Acrylamide results in increased expression of CDKN1A protein modified form CTD PMID:20734998 acrylamide multiple interactions ISO RGD:69328 6480464 [FOXO3 mRNA co-treated with Acrylamide] results in increased expression of CDKN1A protein more ... CTD PMID:33582169 acrylamide multiple interactions EXP 6480464 [Acrylamide co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in decreased expression of CDKN1A protein, ATF3 protein promotes the reaction [Acrylamide results in increased expression of CDKN1A protein] CTD PMID:25531190 , PMID:30409764 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of CDKN1A protein CTD PMID:25531190 acrylamide increases expression ISO RGD:69328 6480464 Acrylamide results in increased expression of CDKN1A mRNA, Acrylamide results in increased expression of CDKN1A protein CTD PMID:28959563 , PMID:33582169 acrylamide decreases expression ISO RGD:735341 6480464 Acrylamide results in decreased expression of CDKN1A protein modified form CTD PMID:20734998 acrylonitrile increases expression ISO RGD:69328 6480464 Acrylonitrile results in increased expression of CDKN1A mRNA CTD PMID:10451498 , PMID:26332274 acrylonitrile increases expression ISO RGD:735341 6480464 Acrylonitrile results in increased expression of CDKN1A protein CTD PMID:33132245 acrylonitrile decreases expression ISO RGD:735341 6480464 Acrylonitrile results in decreased expression of CDKN1A protein CTD PMID:30236600 acrylonitrile multiple interactions ISO RGD:69328 6480464 Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CDKN1A mRNA] more ... CTD PMID:26332274 Actein increases expression ISO RGD:735341 6480464 actein results in increased expression of CDKN1A protein CTD PMID:14758092 acteoside multiple interactions ISO RGD:735341 6480464 acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein], acteoside promotes the reaction [CDKN1A protein binds to CDK6 protein] CTD PMID:17634406 acteoside increases expression ISO RGD:735341 6480464 acteoside results in increased expression of CDKN1A mRNA, acteoside results in increased expression of CDKN1A protein CTD PMID:17634406 actinomycin D multiple interactions ISO RGD:735341 6480464 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone inhibits the reaction [Dactinomycin results in increased expression of and affects the localization of CDKN1A protein], Dactinomycin results in increased expression of and affects the localization of CDKN1A protein CTD PMID:12807743 actinomycin D decreases expression ISO RGD:735341 6480464 Dactinomycin results in decreased expression of CDKN1A protein CTD PMID:14601052 adefovir pivoxil increases expression ISO RGD:735341 6480464 adefovir dipivoxil results in increased expression of CDKN1A mRNA CTD PMID:25596134 adenine decreases expression ISO RGD:735341 6480464 Adenine results in decreased expression of CDKN1A mRNA CTD PMID:24211769 afimoxifene multiple interactions ISO RGD:735341 6480464 afimoxifene inhibits the reaction [Estrogens results in decreased expression of CDKN1A mRNA] CTD PMID:21233418 afimoxifene increases expression ISO RGD:735341 6480464 afimoxifene results in increased expression of CDKN1A mRNA CTD PMID:12154049 aflatoxin B1 affects expression ISO RGD:735341 6480464 Aflatoxin B1 affects the expression of CDKN1A protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO RGD:69328 6480464 Aflatoxin B1 results in decreased expression of CDKN1A mRNA CTD PMID:26260870 aflatoxin B1 increases expression ISO RGD:69328 6480464 Aflatoxin B1 results in increased expression of CDKN1A mRNA CTD PMID:14600272 more ... aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of CDKN1A mRNA, Aflatoxin B1 results in increased expression of CDKN1A protein CTD PMID:19770486 , PMID:29274131 aflatoxin B1 increases expression ISO RGD:735341 6480464 Aflatoxin B1 results in increased expression of CDKN1A mRNA, Aflatoxin B1 results in increased expression of CDKN1A protein CTD PMID:21527772 more ... aldehydo-D-glucosamine increases expression ISO RGD:69328 6480464 Glucosamine results in increased expression of CDKN1A protein CTD PMID:15654767 aldehydo-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of CDKN1A mRNA CTD PMID:17178593 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of CDKN1A mRNA CTD PMID:17178593 aldehydo-D-glucose decreases expression ISO RGD:735341 6480464 Glucose results in decreased expression of CDKN1A protein CTD PMID:33992720 aldehydo-D-glucose multiple interactions ISO RGD:69328 6480464 Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter] more ... CTD PMID:22561310 , PMID:27652271 aldehydo-D-glucose increases expression ISO RGD:69328 6480464 Glucose results in increased expression of CDKN1A mRNA, Glucose results in increased expression of CDKN1A protein CTD PMID:22561310 , PMID:27652271 aldehydo-D-glucose increases expression ISO RGD:735341 6480464 Glucose results in increased expression of CDKN1A mRNA, Glucose results in increased expression of CDKN1A protein CTD PMID:27049278 , PMID:35264022 aldehydo-D-glucose multiple interactions ISO RGD:735341 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA more ... CTD PMID:24451382 more ... all-trans-retinoic acid multiple interactions ISO RGD:735341 6480464 [N1-(2-aminophenyl)-N8-phenyloctanediamide co-treated with Tretinoin] results in increased expression of CDKN1A more ... CTD PMID:12130515 more ... all-trans-retinoic acid decreases expression ISO RGD:735341 6480464 Tretinoin results in decreased expression of CDKN1A mRNA CTD PMID:21924320 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of CDKN1A protein CTD PMID:18425745 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of CDKN1A protein CTD PMID:15949692 all-trans-retinoic acid increases expression ISO RGD:735341 6480464 Tretinoin results in increased expression of CDKN1A more ... CTD PMID:11519864 more ... allyl isothiocyanate increases expression ISO RGD:735341 6480464 allyl isothiocyanate results in increased expression of CDKN1A mRNA CTD PMID:17937621 Allylamine multiple interactions ISO RGD:69328 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1A protein] CTD PMID:15048878 Allylamine increases expression ISO RGD:69328 6480464 Allylamine results in increased expression of CDKN1A protein CTD PMID:15048878 alpha-naphthoflavone multiple interactions ISO RGD:735341 6480464 alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene promotes the reaction [eupatorin-5-methyl ether results in increased expression of CDKN1A protein]] more ... CTD PMID:21887816 more ... alpha-phellandrene increases expression ISO RGD:735341 6480464 alpha phellandrene results in increased expression of CDKN1A mRNA CTD PMID:25075043 alpha-pinene multiple interactions ISO RGD:735341 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CDKN1A mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of CDKN1A mRNA CTD PMID:32699268 aluminium oxide increases expression ISO RGD:735341 6480464 Aluminum Oxide analog results in increased expression of CDKN1A mRNA CTD PMID:23132795 alvocidib multiple interactions ISO RGD:735341 6480464 [alvocidib co-treated with Gemcitabine] results in increased expression of CDKN1A protein more ... CTD PMID:15014036 , PMID:15770523 alvocidib decreases expression EXP 6480464 alvocidib results in decreased expression of CDKN1A protein CTD PMID:12734434 alvocidib increases cleavage ISO RGD:735341 6480464 alvocidib results in increased cleavage of CDKN1A protein CTD PMID:10537362 alvocidib increases expression ISO RGD:735341 6480464 alvocidib results in increased expression of CDKN1A protein CTD PMID:15180955 alvocidib decreases expression ISO RGD:735341 6480464 alvocidib results in decreased expression of CDKN1A protein CTD PMID:15014036 alvocidib affects expression ISO RGD:735341 6480464 alvocidib affects the expression of CDKN1A protein CTD PMID:10537362 amentoflavone multiple interactions ISO RGD:735341 6480464 amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein] CTD PMID:28185818 amifostine decreases expression ISO RGD:735341 6480464 Amifostine results in decreased expression of CDKN1A mRNA CTD PMID:14555708 amifostine increases expression ISO RGD:735341 6480464 Amifostine results in increased expression of CDKN1A protein CTD PMID:12618886 amlodipine increases expression ISO RGD:735341 6480464 Amlodipine results in increased expression of CDKN1A protein CTD PMID:17217918 , PMID:18298949 ammonium chloride increases expression ISO RGD:69328 6480464 Ammonium Chloride results in increased expression of CDKN1A mRNA CTD PMID:12420312 ammonium chloride affects expression ISO RGD:69328 6480464 Ammonium Chloride affects the expression of CDKN1A mRNA CTD PMID:16483693 amodiaquine affects expression ISO RGD:735341 6480464 Amodiaquine affects the expression of CDKN1A mRNA, Amodiaquine affects the expression of CDKN1A protein CTD PMID:24113242 amosite asbestos decreases methylation ISO RGD:735341 6480464 Asbestos, Amosite results in decreased methylation of CDKN1A gene CTD PMID:30990028 amphetamine increases expression ISO RGD:69328 6480464 Amphetamine results in increased expression of CDKN1A mRNA CTD PMID:30779732 amphibole asbestos increases expression ISO RGD:735341 6480464 Asbestos, Amphibole results in increased expression of CDKN1A protein CTD PMID:20705543 , PMID:20855422 andrographolide increases expression ISO RGD:735341 6480464 andrographolide results in increased expression of CDKN1A protein CTD PMID:18619950 , PMID:23845849 anilines increases expression ISO RGD:735341 6480464 Aniline Compounds results in increased expression of CDKN1A protein CTD PMID:25123791 anthocyanin increases expression ISO RGD:735341 6480464 Anthocyanins results in increased expression of CDKN1A protein CTD PMID:27444805 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:735341 6480464 pyrazolanthrone inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein] more ... CTD PMID:15961274 more ... anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:69328 6480464 pyrazolanthrone promotes the reaction [Diethylnitrosamine results in increased expression of CDKN1A protein] CTD PMID:19418558 anthra[1,9-cd]pyrazol-6(2H)-one increases expression ISO RGD:735341 6480464 pyrazolanthrone results in increased expression of CDKN1A protein CTD PMID:16061660 anthracen-2-amine increases expression ISO RGD:69328 6480464 2-anthramine results in increased expression of CDKN1A mRNA CTD PMID:23038007 antimony(0) increases expression ISO RGD:735341 6480464 Antimony results in increased expression of CDKN1A mRNA CTD PMID:17547211 antirheumatic drug decreases expression ISO RGD:735341 6480464 Antirheumatic Agents results in decreased expression of CDKN1A mRNA CTD PMID:24449571 apigenin multiple interactions ISO RGD:735341 6480464 Apigenin promotes the reaction [CDKN1A protein binds to PCNA protein], TP53 protein affects the reaction [Apigenin results in increased expression of CDKN1A protein] CTD PMID:11790449 , PMID:26872304 apigenin increases expression ISO RGD:69328 6480464 Apigenin results in increased expression of CDKN1A mRNA CTD PMID:31201582 apigenin increases expression ISO RGD:735341 6480464 Apigenin results in increased expression of CDKN1A mRNA, Apigenin results in increased expression of CDKN1A protein CTD PMID:11790449 more ... aprepitant multiple interactions ISO RGD:735341 6480464 [Arsenic Trioxide co-treated with Aprepitant] results in increased expression of CDKN1A mRNA CTD PMID:30145367 aripiprazole multiple interactions ISO RGD:735341 6480464 [Aripiprazole co-treated with Ozone] results in increased expression of CDKN1A mRNA CTD PMID:31476115 aristolochic acid A increases expression ISO RGD:735341 6480464 aristolochic acid I results in increased expression of CDKN1A mRNA CTD PMID:33212167 aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of CDKN1A protein CTD PMID:31602497 aristolochic acids multiple interactions ISO RGD:735341 6480464 Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of CDKN1A protein] CTD PMID:24792323 aristolochic acids increases expression ISO RGD:735341 6480464 Aristolochic Acids results in increased expression of CDKN1A protein CTD PMID:24792323 Aroclor 1254 increases expression ISO RGD:735341 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of CDKN1A mRNA CTD PMID:16934159 Aroclor 1254 decreases expression ISO RGD:735341 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of CDKN1A mRNA CTD PMID:17851650 arsane increases expression ISO RGD:735341 6480464 Arsenic results in increased expression of CDKN1A mRNA CTD PMID:11134558 , PMID:29248574 arsane multiple interactions ISO RGD:735341 6480464 [silybin co-treated with Arsenic] results in increased expression of CDKN1A protein, UCA1 mRNA promotes the reaction [Arsenic results in increased expression of CDKN1A mRNA] CTD PMID:25868784 , PMID:29248574 arsenic atom increases expression ISO RGD:735341 6480464 Arsenic results in increased expression of CDKN1A mRNA CTD PMID:11134558 , PMID:29248574 arsenic atom multiple interactions ISO RGD:735341 6480464 [silybin co-treated with Arsenic] results in increased expression of CDKN1A protein, UCA1 mRNA promotes the reaction [Arsenic results in increased expression of CDKN1A mRNA] CTD PMID:25868784 , PMID:29248574 arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of CDKN1A mRNA, arsenite results in decreased expression of CDKN1A protein CTD PMID:16739126 more ... arsenite(3-) increases expression ISO RGD:735341 6480464 arsenite results in increased expression of CDKN1A protein CTD PMID:23715767 arsenite(3-) multiple interactions ISO RGD:735341 6480464 arsenite promotes the reaction [G3BP1 protein binds to CDKN1A mRNA], EPAS1 protein affects the reaction [arsenite results in decreased expression of CDKN1A mRNA] CTD PMID:22447124 , PMID:32406909 arsenite(3-) decreases expression ISO RGD:735341 6480464 arsenite results in decreased expression of CDKN1A mRNA CTD PMID:22447124 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of CDKN1A mRNA, arsenite results in increased expression of CDKN1A protein CTD PMID:23396362 , PMID:33010264 arsenite(3-) multiple interactions EXP 6480464 AKT1 protein modified form inhibits the reaction [arsenite results in increased expression of CDKN1A protein] more ... CTD PMID:18929588 , PMID:23396362 arsenous acid increases sumoylation ISO RGD:735341 6480464 Arsenic Trioxide results in increased sumoylation of CDKN1A protein CTD PMID:28318385 arsenous acid decreases expression ISO RGD:735341 6480464 Arsenic Trioxide results in decreased expression of CDKN1A mRNA CTD PMID:29159499 arsenous acid increases expression ISO RGD:69328 6480464 Arsenic Trioxide results in increased expression of CDKN1A mRNA, Arsenic Trioxide results in increased expression of CDKN1A protein CTD PMID:17487067 more ... arsenous acid affects expression ISO RGD:735341 6480464 Arsenic Trioxide affects the expression of CDKN1A mRNA, Arsenic Trioxide affects the expression of CDKN1A protein CTD PMID:12749819 more ... arsenous acid multiple interactions ISO RGD:735341 6480464 1 more ... CTD PMID:10850458 more ... arsenous acid increases stability ISO RGD:735341 6480464 Arsenic Trioxide results in increased stability of CDKN1A protein CTD PMID:21278055 arsenous acid increases expression ISO RGD:735341 6480464 Arsenic Trioxide results in increased expression of CDKN1A mRNA, Arsenic Trioxide results in increased expression of CDKN1A protein CTD PMID:10850458 more ... arsenous acid decreases methylation ISO RGD:735341 6480464 Arsenic Trioxide results in decreased methylation of CDKN1A promoter CTD PMID:29159499 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of CDKN1A mRNA, Arsenic Trioxide results in increased expression of CDKN1A protein CTD PMID:15073043 more ... arsenous acid increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to Arsenic Trioxide CTD PMID:16283431 , PMID:24801890 arsenous acid multiple interactions ISO RGD:69328 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein], pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA] CTD PMID:17487067 , PMID:23337567 arsenous acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein] more ... CTD PMID:21565247 asbestos increases expression ISO RGD:735341 6480464 Asbestos results in increased expression of CDKN1A protein CTD PMID:11453316 aspartame affects localization ISO RGD:735341 6480464 Aspartame affects the localization of CDKN1A protein CTD PMID:33992720 aspartame multiple interactions ISO RGD:735341 6480464 TAS1R1 protein affects the reaction [Aspartame affects the localization of CDKN1A protein] CTD PMID:33992720 atorvastatin calcium multiple interactions ISO RGD:735341 6480464 [Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1A protein, CDKN1A protein mutant form inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein] CTD PMID:18172863 , PMID:20876807 atorvastatin calcium increases expression ISO RGD:735341 6480464 Atorvastatin results in increased expression of CDKN1A protein CTD PMID:20876807 atrazine increases expression ISO RGD:735341 6480464 Atrazine results in increased expression of CDKN1A mRNA CTD PMID:24211529 atrazine multiple interactions ISO RGD:735341 6480464 Atrazine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA], Tetradecanoylphorbol Acetate promotes the reaction [Atrazine results in increased expression of CDKN1A mRNA] CTD PMID:24211529 aucubin multiple interactions EXP 6480464 aucubin inhibits the reaction [Cisplatin results in increased expression of CDKN1A protein] CTD PMID:32504734 auranofin increases expression ISO RGD:735341 6480464 Auranofin results in increased expression of CDKN1A protein CTD PMID:20542334 Aurin increases expression ISO RGD:735341 6480464 aurin results in increased expression of CDKN1A mRNA CTD PMID:25477506 azadirachtin A increases expression ISO RGD:735341 6480464 azadirachtin results in increased expression of CDKN1A mRNA, azadirachtin results in increased expression of CDKN1A protein CTD PMID:20429769 azathioprine increases expression ISO RGD:735341 6480464 Azathioprine results in increased expression of CDKN1A mRNA, Azathioprine results in increased expression of CDKN1A protein CTD PMID:22623647 , PMID:27358234 azoxystrobin multiple interactions ISO RGD:69328 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CDKN1A mRNA CTD PMID:33854195 baicalein multiple interactions ISO RGD:735341 6480464 baicalein inhibits the reaction [Mitomycin results in increased expression of CDKN1A protein] CTD PMID:34624459 belinostat multiple interactions ISO RGD:735341 6480464 belinostat promotes the reaction [decitabine results in increased expression of CDKN1A mRNA], belinostat promotes the reaction [decitabine results in increased expression of CDKN1A protein] CTD PMID:19234609 belinostat increases expression ISO RGD:735341 6480464 belinostat results in increased expression of CDKN1A mRNA, belinostat results in increased expression of CDKN1A protein CTD PMID:19234609 , PMID:19606018 benzene increases expression ISO RGD:735341 6480464 Benzene results in increased expression of CDKN1A protein CTD PMID:20850422 benzene decreases response to substance ISO RGD:735341 6480464 CDKN1A gene results in decreased susceptibility to Benzene CTD PMID:19505915 benzene increases expression EXP 6480464 Benzene results in increased expression of CDKN1A mRNA, Benzene results in increased expression of CDKN1A protein CTD PMID:11274754 more ... benzene multiple interactions EXP 6480464 AHR protein affects the reaction [Benzene results in increased expression of CDKN1A protein] more ... CTD PMID:11274754 more ... benzo[a]pyrene increases expression ISO RGD:735341 6480464 Benzo(a)pyrene results in increased expression of CDKN1A mRNA, Benzo(a)pyrene results in increased expression of CDKN1A protein CTD PMID:11782367 more ... benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of CDKN1A protein CTD PMID:28681665 benzo[a]pyrene decreases methylation ISO RGD:735341 6480464 Benzo(a)pyrene results in decreased methylation of CDKN1A 5' UTR CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:735341 6480464 Benzo(a)pyrene affects the methylation of CDKN1A promoter CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:735341 6480464 Benzo(a)pyrene results in increased methylation of CDKN1A 3' UTR CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:69328 6480464 Benzo(a)pyrene results in increased expression of CDKN1A mRNA, Benzo(a)pyrene results in increased expression of CDKN1A protein CTD PMID:15459018 , PMID:26086121 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene metabolite results in increased expression of CDKN1A mRNA more ... CTD PMID:19770486 more ... benzo[a]pyrene decreases expression ISO RGD:735341 6480464 Benzo(a)pyrene results in decreased expression of CDKN1A protein CTD PMID:29126329 , PMID:30236600 benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CDKN1A mRNA more ... CTD PMID:21995607 more ... benzo[a]pyrene multiple interactions ISO RGD:69328 6480464 pifithrin inhibits the reaction [Benzo(a)pyrene results in increased expression of CDKN1A mRNA] more ... CTD PMID:15459018 , PMID:26086121 benzo[a]pyrene affects expression ISO RGD:735341 6480464 Benzo(a)pyrene affects the expression of CDKN1A mRNA CTD PMID:20624995 benzo[a]pyrene decreases degradation ISO RGD:735341 6480464 Benzo(a)pyrene results in decreased degradation of CDKN1A protein CTD PMID:15625077 benzo[a]pyrene multiple interactions ISO RGD:735341 6480464 2 more ... CTD PMID:15625077 more ... benzo[a]pyrene diol epoxide I increases expression ISO RGD:735341 6480464 7 more ... CTD PMID:11782367 more ... benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CDKN1A mRNA CTD PMID:27858113 benzo[b]fluoranthene increases expression EXP 6480464 benzo(b)fluoranthene results in increased expression of CDKN1A mRNA CTD PMID:26377693 Benzo[ghi]perylene increases expression EXP 6480464 1, 12-benzoperylene results in increased expression of CDKN1A mRNA CTD PMID:26377693 benzyl isothiocyanate increases expression ISO RGD:735341 6480464 benzyl isothiocyanate results in increased expression of CDKN1A mRNA CTD PMID:17937621 berberine increases expression ISO RGD:735341 6480464 Berberine results in increased expression of CDKN1A protein CTD PMID:16505103 , PMID:23747414 beryllium sulfate multiple interactions ISO RGD:735341 6480464 beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter] CTD PMID:17395767 beryllium sulfate increases expression ISO RGD:735341 6480464 beryllium sulfate results in increased expression of CDKN1A mRNA, beryllium sulfate results in increased expression of CDKN1A protein CTD PMID:17395767 Besigomsin multiple interactions EXP 6480464 schizandrol B inhibits the reaction [Acetaminophen results in increased activity of CDKN1A protein], schizandrol B inhibits the reaction [Acetaminophen results in increased expression of CDKN1A protein] CTD PMID:25319358 beta-D-glucosamine increases expression ISO RGD:69328 6480464 Glucosamine results in increased expression of CDKN1A protein CTD PMID:15654767 beta-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of CDKN1A mRNA CTD PMID:17178593 beta-naphthoflavone multiple interactions ISO RGD:69328 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDKN1A mRNA CTD PMID:18164116 beta-naphthoflavone decreases expression ISO RGD:69328 6480464 beta-Naphthoflavone results in decreased expression of CDKN1A mRNA, beta-Naphthoflavone results in decreased expression of CDKN1A protein CTD PMID:19389873 , PMID:22687991 betalain increases expression ISO RGD:735341 6480464 Betalains results in increased expression of CDKN1A mRNA CTD PMID:33522684 betulinic acid increases expression ISO RGD:735341 6480464 Betulinic Acid analog results in increased expression of CDKN1A protein CTD PMID:28254521 bexarotene increases expression ISO RGD:735341 6480464 bexarotene results in increased expression of CDKN1A protein CTD PMID:19067706 bexarotene multiple interactions ISO RGD:69328 6480464 [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDKN1A protein], Bexarotene affects the reaction [Azoxymethane affects the expression of CDKN1A protein] CTD PMID:24080207 bicalutamide increases expression ISO RGD:735341 6480464 bicalutamide results in increased expression of CDKN1A more ... CTD PMID:11845989 , PMID:15638997 bicalutamide multiple interactions ISO RGD:735341 6480464 [bicalutamide co-treated with Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein CTD PMID:27132804 bifenthrin multiple interactions ISO RGD:69328 6480464 bifenthrin inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:21251947 biochanin A decreases expression ISO RGD:735341 6480464 biochanin A results in decreased expression of CDKN1A protein CTD PMID:12111696 biotin decreases expression EXP 6480464 Biotin results in decreased expression of CDKN1A mRNA CTD PMID:34699867 biphenyl-4-amine increases expression ISO RGD:735341 6480464 4-biphenylamine results in increased expression of CDKN1A mRNA CTD PMID:32905825 biphenyl-4-amine multiple interactions ISO RGD:735341 6480464 TP53 protein inhibits the reaction [4-biphenylamine results in increased expression of CDKN1A mRNA] CTD PMID:32905825 bis(2-chloroethyl) sulfide affects expression ISO RGD:69328 6480464 Mustard Gas affects the expression of CDKN1A mRNA CTD PMID:15651846 bis(2-chloroethyl) sulfide increases expression ISO RGD:735341 6480464 Mustard Gas results in increased expression of CDKN1A mRNA CTD PMID:25102026 , PMID:33491125 bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of CDKN1A mRNA CTD PMID:15674843 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of CDKN1A mRNA CTD PMID:25701202 , PMID:31211961 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:69328 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CDKN1A mRNA CTD PMID:35762964 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:33316053 bis(2-ethylhexyl) phthalate increases expression ISO RGD:735341 6480464 Diethylhexyl Phthalate results in increased expression of CDKN1A mRNA, Diethylhexyl Phthalate results in increased expression of CDKN1A protein CTD PMID:29110037 , PMID:31163220 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of CDKN1A mRNA CTD PMID:28123099 bisphenol A affects expression ISO RGD:735341 6480464 bisphenol A affects the expression of CDKN1A mRNA CTD PMID:22307313 , PMID:30903817 bisphenol A increases expression ISO RGD:735341 6480464 bisphenol A results in increased expression of CDKN1A mRNA, bisphenol A results in increased expression of CDKN1A protein CTD PMID:29383186 , PMID:31470548 bisphenol A increases expression ISO RGD:69328 6480464 bisphenol A results in increased expression of CDKN1A protein CTD PMID:24884420 bisphenol A decreases expression ISO RGD:69328 6480464 bisphenol A results in decreased expression of CDKN1A mRNA, bisphenol A results in decreased expression of CDKN1A protein CTD PMID:24884420 more ... bisphenol A affects expression ISO RGD:69328 6480464 bisphenol A affects the expression of CDKN1A mRNA CTD PMID:25181051 , PMID:32145629 bisphenol A multiple interactions ISO RGD:69328 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CDKN1A mRNA more ... CTD PMID:24884420 more ... bisphenol A multiple interactions ISO RGD:735341 6480464 [bisphenol A co-treated with cylindrospermopsin] results in increased expression of CDKN1A mRNA more ... CTD PMID:23222814 more ... bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CDKN1A mRNA CTD PMID:20826375 more ... bisphenol A decreases expression ISO RGD:735341 6480464 bisphenol A results in decreased expression of CDKN1A more ... CTD PMID:16474171 more ... bisphenol F multiple interactions ISO RGD:735341 6480464 [bisphenol F co-treated with cylindrospermopsin] results in increased expression of CDKN1A mRNA CTD PMID:32244372 bisphenol F multiple interactions ISO RGD:69328 6480464 [bisphenol A co-treated with bisphenol F co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CDKN1A mRNA CTD PMID:36041667 bleomycin A2 increases expression EXP 6480464 Bleomycin results in increased expression of CDKN1A mRNA CTD PMID:26345256 , PMID:29720568 bortezomib multiple interactions ISO RGD:735341 6480464 [Bortezomib co-treated with Butyrates] results in increased cleavage of CDKN1A protein more ... CTD PMID:12893773 more ... bortezomib decreases response to substance ISO RGD:735341 6480464 CDKN1A results in decreased susceptibility to Bortezomib CTD PMID:16928825 bortezomib increases expression ISO RGD:735341 6480464 Bortezomib results in increased expression of CDKN1A mRNA, Bortezomib results in increased expression of CDKN1A protein CTD PMID:12902978 more ... bortezomib increases stability ISO RGD:735341 6480464 Bortezomib results in increased stability of CDKN1A protein CTD PMID:15543232 bosutinib increases expression EXP 6480464 bosutinib results in increased expression of CDKN1A protein CTD PMID:17129604 brassinolide increases expression ISO RGD:735341 6480464 brassinolide results in increased expression of CDKN1A protein CTD PMID:20833159 bromobenzene increases expression ISO RGD:69328 6480464 bromobenzene results in increased expression of CDKN1A mRNA CTD PMID:32479839 bromochloroacetic acid decreases expression ISO RGD:69328 6480464 bromochloroacetic acid results in decreased expression of CDKN1A mRNA CTD PMID:16460773 bucladesine increases expression ISO RGD:69328 6480464 Bucladesine results in increased expression of CDKN1A protein CTD PMID:16718685 bucladesine multiple interactions ISO RGD:735341 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CDKN1A mRNA more ... CTD PMID:20823114 , PMID:22534328 bucladesine multiple interactions ISO RGD:69328 6480464 GJA1 promotes the reaction [Bucladesine results in increased expression of CDKN1A protein] CTD PMID:16718685 budesonide multiple interactions EXP 6480464 Budesonide inhibits the reaction [vinyl carbamate results in decreased expression of CDKN1A protein] CTD PMID:12117777 budesonide increases expression EXP 6480464 Budesonide results in increased expression of CDKN1A mRNA CTD PMID:12117777 busulfan increases expression ISO RGD:735341 6480464 Busulfan results in increased expression of CDKN1A protein CTD PMID:16882877 busulfan multiple interactions ISO RGD:735341 6480464 [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased expression of CDKN1A protein CTD PMID:20933509 buta-1,3-diene increases expression EXP 6480464 1, 3-butadiene results in increased expression of CDKN1A mRNA CTD PMID:21147608 , PMID:29038090 butan-1-ol multiple interactions ISO RGD:735341 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of CDKN1A mRNA CTD PMID:29432896 butylated hydroxyanisole multiple interactions ISO RGD:735341 6480464 Hydrogen Peroxide promotes the reaction [Butylated Hydroxyanisole results in increased expression of CDKN1A mRNA] CTD PMID:29486183 butylated hydroxyanisole increases expression ISO RGD:735341 6480464 Butylated Hydroxyanisole results in increased expression of CDKN1A mRNA CTD PMID:29486183 Butylbenzyl phthalate multiple interactions ISO RGD:735341 6480464 MIR19A mRNA affects the reaction [butylbenzyl phthalate results in decreased expression of CDKN1A protein] more ... CTD PMID:29864457 , PMID:30243731 Butylbenzyl phthalate multiple interactions ISO RGD:69328 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CDKN1A mRNA CTD PMID:35762964 Butylbenzyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:33316053 Butylbenzyl phthalate decreases expression ISO RGD:735341 6480464 butylbenzyl phthalate results in decreased expression of CDKN1A mRNA, butylbenzyl phthalate results in decreased expression of CDKN1A protein CTD PMID:29864457 , PMID:30243731 Butylparaben decreases expression ISO RGD:735341 6480464 butylparaben results in decreased expression of CDKN1A mRNA, butylparaben results in decreased expression of CDKN1A protein CTD PMID:24481588 butyric acid increases expression ISO RGD:735341 6480464 [Butyric Acid results in increased expression of SRSF2 protein] which results in increased expression of CDKN1A mRNA more ... CTD PMID:15715472 , PMID:21555914 butyric acid multiple interactions ISO RGD:735341 6480464 [Butyric Acid co-treated with Quercetin] results in increased expression of CDKN1A protein CTD PMID:25070040 butyric acid multiple interactions EXP 6480464 [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 more ... CTD PMID:25478867 C.I. Natural Red 20 increases expression ISO RGD:735341 6480464 shikonin results in increased expression of CDKN1A protein CTD PMID:28684144 C.I. Natural Red 20 increases expression ISO RGD:69328 6480464 shikonin results in increased expression of CDKN1A protein CTD PMID:16061028 C60 fullerene decreases expression ISO RGD:69328 6480464 fullerene C60 results in decreased expression of CDKN1A mRNA CTD PMID:19167457 C60 fullerene increases expression ISO RGD:735341 6480464 fullerene C60 analog results in increased expression of CDKN1A protein CTD PMID:20045429 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of CDKN1A mRNA, Cadmium results in increased expression of CDKN1A protein CTD PMID:12189181 , PMID:22666406 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CDKN1A mRNA CTD PMID:31614173 , PMID:35134237 cadmium atom decreases expression ISO RGD:735341 6480464 Cadmium results in decreased expression of CDKN1A mRNA CTD PMID:22562489 cadmium atom increases expression ISO RGD:69328 6480464 Cadmium results in increased expression of CDKN1A protein CTD PMID:16730872 cadmium atom multiple interactions ISO RGD:735341 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased expression of CDKN1A protein] more ... CTD PMID:14647439 more ... cadmium atom increases expression ISO RGD:735341 6480464 Cadmium results in increased expression of CDKN1A mRNA, Cadmium results in increased expression of CDKN1A protein CTD PMID:14647439 , PMID:25101185 cadmium dichloride multiple interactions ISO RGD:735341 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDKN1A protein more ... CTD PMID:12634122 more ... cadmium dichloride multiple interactions ISO RGD:69328 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CDKN1A protein], Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of CDKN1A protein] CTD PMID:36493885 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CDKN1A mRNA CTD PMID:31614173 , PMID:35134237 cadmium dichloride decreases expression ISO RGD:735341 6480464 Cadmium Chloride results in decreased expression of CDKN1A mRNA, Cadmium Chloride results in decreased expression of CDKN1A protein CTD PMID:20219890 , PMID:34520792 cadmium dichloride decreases expression ISO RGD:69328 6480464 Cadmium Chloride results in decreased expression of CDKN1A mRNA CTD PMID:33453195 cadmium dichloride decreases methylation ISO RGD:69328 6480464 Cadmium Chloride results in decreased methylation of CDKN1A promoter CTD PMID:22457795 cadmium dichloride affects expression ISO RGD:69328 6480464 Cadmium Chloride affects the expression of CDKN1A mRNA CTD PMID:22110744 cadmium dichloride increases expression ISO RGD:735341 6480464 Cadmium Chloride results in increased expression of CDKN1A mRNA, Cadmium Chloride results in increased expression of CDKN1A protein CTD PMID:25111876 more ... cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of CDKN1A mRNA, Cadmium Chloride results in increased expression of CDKN1A protein CTD PMID:18974090 more ... cadmium dichloride increases expression ISO RGD:69328 6480464 Cadmium Chloride results in increased expression of CDKN1A protein CTD PMID:16730872 , PMID:36493885 cadmium sulfate increases expression ISO RGD:735341 6480464 cadmium sulfate results in increased expression of CDKN1A mRNA CTD PMID:21783983 cadmium sulfate increases expression EXP 6480464 cadmium sulfate results in increased expression of CDKN1A mRNA CTD PMID:19274763 caffeine multiple interactions ISO RGD:735341 6480464 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2 more ... CTD PMID:17977830 more ... caffeine multiple interactions EXP 6480464 3-(2 more ... CTD PMID:30555576 calcidiol increases expression ISO RGD:735341 6480464 Calcifediol results in increased expression of CDKN1A protein CTD PMID:21542014 calciol decreases expression ISO RGD:735341 6480464 Cholecalciferol results in decreased expression of CDKN1A mRNA, Cholecalciferol results in decreased expression of CDKN1A protein CTD PMID:12907249 , PMID:24451003 calciol increases expression ISO RGD:735341 6480464 Cholecalciferol results in increased expression of CDKN1A mRNA CTD PMID:21801466 calciol multiple interactions ISO RGD:735341 6480464 Cholecalciferol promotes the reaction [fludarabine results in increased expression of CDKN1A mRNA] CTD PMID:21801466 calcitriol multiple interactions ISO RGD:735341 6480464 [Calcitriol co-treated with Genistein] results in increased expression of CDKN1A mRNA more ... CTD PMID:15955619 more ... calcitriol increases expression ISO RGD:735341 6480464 Calcitriol results in increased expression of CDKN1A more ... CTD PMID:10825140 more ... Calpeptin increases expression EXP 6480464 calpeptin results in increased expression of CDKN1A protein CTD PMID:22432027 calycosin decreases expression ISO RGD:735341 6480464 7, 3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CDKN1A mRNA CTD PMID:24455688 calyculin a multiple interactions ISO RGD:735341 6480464 calyculin A inhibits the reaction [N-caproylsphingosine results in increased expression of CDKN1A protein] CTD PMID:25195822 camptothecin increases expression ISO RGD:735341 6480464 Camptothecin results in increased expression of CDKN1A mRNA, Camptothecin results in increased expression of CDKN1A protein CTD PMID:17555331 more ... camptothecin multiple interactions ISO RGD:735341 6480464 Aspirin inhibits the reaction [Camptothecin results in increased expression of CDKN1A protein] more ... CTD PMID:19212664 , PMID:30885713 cannabidiol increases expression EXP 6480464 Cannabidiol results in increased expression of CDKN1A mRNA CTD PMID:21542829 more ... cannabidiol decreases expression ISO RGD:735341 6480464 Cannabidiol results in decreased expression of CDKN1A mRNA CTD PMID:27918106 cannabidiol multiple interactions ISO RGD:735341 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of CDKN1A mRNA CTD PMID:30096889 cannabidiol increases expression ISO RGD:735341 6480464 Cannabidiol results in increased expression of CDKN1A mRNA, Cannabidiol results in increased expression of CDKN1A protein CTD PMID:31349651 , PMID:36519830 cannabidiol multiple interactions EXP 6480464 [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CDKN1A mRNA CTD PMID:30742662 capsaicin decreases expression ISO RGD:735341 6480464 Capsaicin results in decreased expression of CDKN1A protein CTD PMID:22226932 capsaicin increases expression ISO RGD:735341 6480464 Capsaicin results in increased expression of CDKN1A mRNA, Capsaicin results in increased expression of CDKN1A protein CTD PMID:16540674 more ... Carbadox increases expression ISO RGD:69328 6480464 Carbadox results in increased expression of CDKN1A mRNA, Carbadox results in increased expression of CDKN1A protein CTD PMID:26558467 carbamazepine affects expression ISO RGD:735341 6480464 Carbamazepine affects the expression of CDKN1A mRNA CTD PMID:25979313 carbofuran increases expression ISO RGD:69328 6480464 Carbofuran results in increased expression of CDKN1A mRNA, Carbofuran results in increased expression of CDKN1A protein CTD PMID:28982980 carbofuran multiple interactions ISO RGD:69328 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased expression of CDKN1A protein] CTD PMID:28982980 carbon nanotube increases expression ISO RGD:735341 6480464 Nanotubes, Carbon results in increased expression of CDKN1A mRNA CTD PMID:24389112 carbon nanotube decreases methylation ISO RGD:735341 6480464 Nanotubes, Carbon results in decreased methylation of CDKN1A gene CTD PMID:30990028 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon results in increased expression of CDKN1A mRNA CTD PMID:25554681 , PMID:25620056 carbon nanotube affects expression EXP 6480464 Nanotubes, Carbon analog affects the expression of CDKN1A mRNA CTD PMID:25554681 , PMID:25620056 carboplatin increases expression ISO RGD:735341 6480464 Carboplatin results in increased expression of CDKN1A protein CTD PMID:9664115 carboplatin increases expression ISO RGD:69328 6480464 Carboplatin results in increased expression of CDKN1A mRNA CTD PMID:18172885 Cardanol increases expression ISO RGD:735341 6480464 cardanol results in increased expression of CDKN1A mRNA, cardanol results in increased expression of CDKN1A protein CTD PMID:26694491 carmustine multiple interactions ISO RGD:735341 6480464 [Carmustine co-treated with O(6)-benzylguanine] results in increased expression of CDKN1A protein, MDM4 protein promotes the reaction [Carmustine results in increased expression of CDKN1A protein] CTD PMID:15735757 , PMID:20472715 carmustine increases expression ISO RGD:735341 6480464 Carmustine results in increased expression of CDKN1A protein CTD PMID:15735757 more ... casticin decreases expression ISO RGD:735341 6480464 casticin results in decreased expression of CDKN1A mRNA, casticin results in decreased expression of CDKN1A protein CTD PMID:27862857 , PMID:29098808 catechol increases expression ISO RGD:69328 6480464 catechol results in increased expression of CDKN1A protein CTD PMID:23535288 cefaloridine decreases expression ISO RGD:69328 6480464 Cephaloridine results in decreased expression of CDKN1A mRNA CTD PMID:18500788 celecoxib multiple interactions ISO RGD:735341 6480464 [Atorvastatin co-treated with Celecoxib] results in increased expression of CDKN1A protein more ... CTD PMID:18172863 more ... celecoxib increases localization ISO RGD:735341 6480464 Celecoxib results in increased localization of CDKN1A protein CTD PMID:19706164 celecoxib increases expression ISO RGD:735341 6480464 Celecoxib results in increased expression of CDKN1A mRNA, Celecoxib results in increased expression of CDKN1A protein CTD PMID:16136956 more ... cerium trichloride decreases expression EXP 6480464 cerous chloride results in decreased expression of CDKN1A mRNA CTD PMID:23139204 cetrorelix increases expression ISO RGD:735341 6480464 cetrorelix results in increased expression of CDKN1A protein CTD PMID:21062912 CGP 52608 multiple interactions ISO RGD:735341 6480464 CGP 52608 promotes the reaction [RORA protein binds to CDKN1A gene] CTD PMID:28238834 CGS-21680 multiple interactions ISO RGD:735341 6480464 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2, 2'-azobis(2-amidinopropane) results in increased expression of CDKN1A protein]] CTD PMID:30555576 chlorambucil increases expression ISO RGD:735341 6480464 Chlorambucil results in increased expression of CDKN1A protein CTD PMID:16039525 chloramphenicol multiple interactions ISO RGD:735341 6480464 CDKN1A mutant form inhibits the reaction [Chloramphenicol inhibits the reaction [Mitomycin results in increased activity of CASP3 protein]] more ... CTD PMID:15905168 chloramphenicol decreases degradation ISO RGD:735341 6480464 Chloramphenicol results in decreased degradation of CDKN1A mRNA CTD PMID:15905168 chloroacetaldehyde increases expression ISO RGD:735341 6480464 chloroacetaldehyde results in increased expression of CDKN1A mRNA CTD PMID:25596134 chloroform increases expression ISO RGD:69328 6480464 Chloroform results in increased expression of CDKN1A mRNA CTD PMID:21813463 chloropicrin increases expression ISO RGD:735341 6480464 chloropicrin results in increased expression of CDKN1A protein CTD PMID:24548678 chloropicrin affects expression ISO RGD:735341 6480464 chloropicrin affects the expression of CDKN1A mRNA CTD PMID:26352163 chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of CDKN1A mRNA CTD PMID:23125180 chloroquine increases activity ISO RGD:735341 6480464 Chloroquine results in increased activity of CDKN1A CTD PMID:18089834 chloroquine multiple interactions ISO RGD:735341 6480464 [Chloroquine co-treated with flavokawain B] results in decreased expression of CDKN1A protein, Chloroquine inhibits the reaction [Doxorubicin results in increased expression of CDKN1A protein] CTD PMID:22927544 , PMID:30025493 chloroquine increases expression ISO RGD:735341 6480464 Chloroquine results in increased expression of CDKN1A protein CTD PMID:12243503 chlorpromazine multiple interactions ISO RGD:69328 6480464 [EGR1 binds to CDKN1A promoter] promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA], EGR1 promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA] CTD PMID:20368687 chlorpromazine increases expression ISO RGD:69328 6480464 Chlorpromazine results in increased expression of CDKN1A mRNA CTD PMID:20368687 chlorpyrifos multiple interactions ISO RGD:69328 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CDKN1A mRNA CTD PMID:33854195 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of CDKN1A mRNA CTD PMID:30378422 chlorpyrifos increases expression ISO RGD:735341 6480464 Chlorpyrifos results in increased expression of CDKN1A mRNA CTD PMID:30981936 cholesterol multiple interactions EXP 6480464 [Cholesterol co-treated with 1, 2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of CDKN1A mRNA CTD PMID:22129739 cholic acid decreases expression EXP 6480464 Cholic Acid results in decreased expression of CDKN1A protein CTD PMID:27151938 cholic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Cholic Acid] results in decreased expression of CDKN1A protein CTD PMID:27151938 choline multiple interactions EXP 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of CDKN1A mRNA more ... CTD PMID:20938992 more ... chromium atom increases expression ISO RGD:735341 6480464 Chromium results in increased expression of CDKN1A mRNA CTD PMID:17547211 chromium atom decreases expression ISO RGD:735341 6480464 Chromium results in decreased expression of CDKN1A mRNA, Chromium results in decreased expression of CDKN1A protein CTD PMID:18602874 chromium atom multiple interactions ISO RGD:735341 6480464 CDKN1A affects the reaction [Chromium results in increased expression of TP53 protein] more ... CTD PMID:18024214 , PMID:18602874 chromium atom increases response to substance ISO RGD:735341 6480464 CDKN1A gene mutant form results in increased susceptibility to Chromium CTD PMID:18024214 chromium(6+) multiple interactions EXP 6480464 [chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of CDKN1A mRNA CTD PMID:25820237 chrysene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CDKN1A mRNA CTD PMID:27858113 chrysin multiple interactions ISO RGD:69328 6480464 chrysin inhibits the reaction [Testosterone results in decreased expression of CDKN1A mRNA] CTD PMID:29247772 chrysin increases expression ISO RGD:735341 6480464 chrysin results in increased expression of CDKN1A mRNA, chrysin results in increased expression of CDKN1A protein CTD PMID:19397994 chymostatin multiple interactions ISO RGD:735341 6480464 chymostatin inhibits the reaction [KRAS protein mutant form results in increased expression of CDKN1A protein] CTD PMID:33380422 cidofovir anhydrous increases expression ISO RGD:735341 6480464 Cidofovir results in increased expression of CDKN1A mRNA, Cidofovir results in increased expression of CDKN1A protein CTD PMID:11697818 , PMID:25596134 ciglitazone decreases expression EXP 6480464 ciglitazone results in decreased expression of CDKN1A CTD PMID:12787395 ciglitazone increases expression ISO RGD:735341 6480464 ciglitazone results in increased expression of CDKN1A protein CTD PMID:19140230 ciguatoxin CTX1B affects expression EXP 6480464 Ciguatoxins affects the expression of CDKN1A mRNA CTD PMID:18353800 cilostazol increases expression ISO RGD:735341 6480464 cilostazol results in increased expression of CDKN1A protein CTD PMID:10642304 Cinobufagin decreases expression ISO RGD:735341 6480464 cinobufagin results in decreased expression of CDKN1A mRNA, cinobufagin results in decreased expression of CDKN1A protein CTD PMID:21215801 ciprofloxacin decreases expression ISO RGD:735341 6480464 Ciprofloxacin results in decreased expression of CDKN1A, Ciprofloxacin results in decreased expression of CDKN1A protein CTD PMID:10741713 more ... cisplatin increases expression ISO RGD:69328 6480464 Cisplatin results in increased expression of CDKN1A mRNA, Cisplatin results in increased expression of CDKN1A protein CTD PMID:18172885 more ... cisplatin multiple interactions ISO RGD:69328 6480464 Cisplatin promotes the reaction [NFE2L2 protein binds to CDKN1A protein] CTD PMID:35842499 cisplatin affects localization ISO RGD:69328 6480464 Cisplatin affects the localization of CDKN1A protein CTD PMID:35842499 cisplatin affects expression ISO RGD:735341 6480464 Cisplatin affects the expression of CDKN1A mRNA, Cisplatin affects the expression of CDKN1A protein CTD PMID:23300844 , PMID:32562082 cisplatin decreases expression ISO RGD:735341 6480464 Cisplatin results in decreased expression of CDKN1A protein CTD PMID:14601052 , PMID:20195699 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of CDKN1A mRNA, Cisplatin results in increased expression of CDKN1A protein CTD PMID:21151649 more ... cisplatin multiple interactions EXP 6480464 aucubin inhibits the reaction [Cisplatin results in increased expression of CDKN1A protein] more ... CTD PMID:21325496 more ... cisplatin decreases response to substance EXP 6480464 CDKN1A protein results in decreased susceptibility to Cisplatin CTD PMID:21325496 cisplatin increases phosphorylation ISO RGD:735341 6480464 Cisplatin results in increased phosphorylation of CDKN1A protein CTD PMID:21750216 cisplatin increases expression ISO RGD:735341 6480464 Cisplatin results in increased expression of CDKN1A more ... CTD PMID:11099651 more ... cisplatin increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to Cisplatin, CDKN1A results in increased susceptibility to Cisplatin CTD PMID:21087528 , PMID:21858171 cisplatin multiple interactions ISO RGD:735341 6480464 (1 more ... CTD PMID:12807743 more ... citric acid multiple interactions ISO RGD:735341 6480464 [Citric Acid co-treated with zinc chloride] results in increased expression of CDKN1A protein CTD PMID:16624386 cladribine increases expression ISO RGD:735341 6480464 Cladribine results in increased expression of CDKN1A mRNA CTD PMID:21801466 cladribine multiple interactions ISO RGD:735341 6480464 Cladribine promotes the reaction [resveratrol results in increased expression of CDKN1A mRNA], resveratrol promotes the reaction [Cladribine results in increased expression of CDKN1A mRNA] CTD PMID:21801466 clobenpropit multiple interactions ISO RGD:735341 6480464 [HRH4 protein results in increased susceptibility to clobenpropit] which results in increased expression of CDKN1A protein CTD PMID:22363581 clodronic acid increases expression ISO RGD:735341 6480464 Clodronic Acid results in increased expression of CDKN1A mRNA CTD PMID:25596134 clofarabine multiple interactions ISO RGD:735341 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[resveratrol co-treated with clofarabine] results in decreased expression of CDKN1A protein] more ... CTD PMID:20933509 , PMID:23146690 clofibrate multiple interactions EXP 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CDKN1A mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CDKN1A mRNA] CTD PMID:17585979 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of CDKN1A mRNA CTD PMID:17585979 clotrimazole decreases expression ISO RGD:735341 6480464 Clotrimazole results in decreased expression of CDKN1A CTD PMID:20724915 cobalt atom multiple interactions ISO RGD:69328 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of CDKN1A mRNA CTD PMID:22198552 cobalt atom increases expression ISO RGD:735341 6480464 Cobalt results in increased expression of CDKN1A mRNA, Cobalt results in increased expression of CDKN1A protein CTD PMID:24068677 cobalt atom multiple interactions ISO RGD:735341 6480464 TP53 protein affects the reaction [Cobalt results in increased expression of CDKN1A mRNA] CTD PMID:24068677 cobalt dichloride multiple interactions ISO RGD:735341 6480464 [cobaltous chloride affects the localization of CDKN1A protein] which results in increased expression of and results in increased stability of CASP3 protein, [cobaltous chloride co-treated with TP53 gene mutant form] results in increased expression of CDKN1A protein CTD PMID:20974702 , PMID:21687937 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of CDKN1A mRNA CTD PMID:16772336 , PMID:24265542 cobalt dichloride multiple interactions EXP 6480464 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [cobaltous chloride results in increased expression of CDKN1A mRNA] CTD PMID:24265542 cobalt dichloride increases expression ISO RGD:735341 6480464 cobaltous chloride results in increased expression of CDKN1A mRNA, cobaltous chloride results in increased expression of CDKN1A protein CTD PMID:19320972 more ... cobalt dichloride affects localization ISO RGD:735341 6480464 cobaltous chloride affects the localization of CDKN1A protein CTD PMID:20974702 cocaine increases expression ISO RGD:69328 6480464 Cocaine results in increased expression of CDKN1A mRNA CTD PMID:27899881 copper atom multiple interactions ISO RGD:69328 6480464 [ATP7B protein affects the susceptibility to Copper] which affects the expression of CDKN1A mRNA CTD PMID:23112546 copper atom decreases expression ISO RGD:69328 6480464 Copper results in decreased expression of CDKN1A mRNA CTD PMID:30556269 copper atom increases expression ISO RGD:735341 6480464 Copper results in increased expression of CDKN1A protein CTD PMID:15880691 copper atom increases expression ISO RGD:69328 6480464 Copper results in increased expression of CDKN1A mRNA CTD PMID:22465980 copper atom multiple interactions ISO RGD:735341 6480464 [Chelating Agents binds to Copper] which results in increased expression of CDKN1A mRNA more ... CTD PMID:16391388 more ... copper(0) multiple interactions ISO RGD:69328 6480464 [ATP7B protein affects the susceptibility to Copper] which affects the expression of CDKN1A mRNA CTD PMID:23112546 copper(0) decreases expression ISO RGD:69328 6480464 Copper results in decreased expression of CDKN1A mRNA CTD PMID:30556269 copper(0) increases expression ISO RGD:735341 6480464 Copper results in increased expression of CDKN1A protein CTD PMID:15880691 copper(0) increases expression ISO RGD:69328 6480464 Copper results in increased expression of CDKN1A mRNA CTD PMID:22465980 copper(0) multiple interactions ISO RGD:735341 6480464 [Chelating Agents binds to Copper] which results in increased expression of CDKN1A mRNA more ... CTD PMID:16391388 more ... copper(II) chloride affects expression ISO RGD:735341 6480464 cupric chloride affects the expression of CDKN1A mRNA CTD PMID:17211630 copper(II) sulfate increases expression ISO RGD:735341 6480464 Copper Sulfate results in increased expression of CDKN1A mRNA, Copper Sulfate results in increased expression of CDKN1A protein CTD PMID:15001399 , PMID:19549813 cordycepin multiple interactions ISO RGD:69328 6480464 cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA] CTD PMID:23690541 cordycepin increases expression EXP 6480464 cordycepin results in increased expression of CDKN1A protein CTD PMID:26303320 corn oil increases expression ISO RGD:69328 6480464 Corn Oil results in increased expression of CDKN1A mRNA CTD PMID:22760963 corn oil affects expression ISO RGD:69328 6480464 Corn Oil affects the expression of CDKN1A mRNA CTD PMID:16360708 corticosterone affects expression ISO RGD:69328 6480464 Corticosterone affects the expression of CDKN1A protein CTD PMID:12807724 corticosterone multiple interactions ISO RGD:69328 6480464 Corticosterone inhibits the reaction [CDKN1A protein binds to CDK4 protein], Corticosterone promotes the reaction [CDKN1A protein binds to CDK2 protein] CTD PMID:12807724 coumarin increases expression ISO RGD:735341 6480464 coumarin analog results in increased expression of CDKN1A mRNA CTD PMID:32578917 coumestrol decreases expression ISO RGD:735341 6480464 Coumestrol results in decreased expression of CDKN1A mRNA CTD PMID:19167446 coumestrol multiple interactions ISO RGD:735341 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CDKN1A mRNA CTD PMID:19167446 crocidolite asbestos increases expression ISO RGD:735341 6480464 Asbestos, Crocidolite results in increased expression of CDKN1A protein CTD PMID:20705543 cryptolepine increases expression ISO RGD:735341 6480464 cryptolepine results in increased expression of CDKN1A mRNA, cryptolepine results in increased expression of CDKN1A protein CTD PMID:16120219 crystal violet multiple interactions ISO RGD:735341 6480464 Gentian Violet promotes the reaction [TP53 protein binds to CDKN1A promoter], Gentian Violet promotes the reaction [TP53 protein results in increased expression of CDKN1A mRNA] CTD PMID:24535435 CU-O LINKAGE increases expression ISO RGD:735341 6480464 cupric oxide results in increased expression of CDKN1A mRNA CTD PMID:32285662 cudraflavone B increases expression ISO RGD:735341 6480464 cudraflavone B results in increased expression of CDKN1A protein CTD PMID:23881456 cudraflavone B multiple interactions ISO RGD:735341 6480464 resveratrol inhibits the reaction [cudraflavone B results in increased expression of CDKN1A protein], sirtinol promotes the reaction [cudraflavone B results in increased expression of CDKN1A protein] CTD PMID:23881456 Cuprizon increases expression ISO RGD:69328 6480464 Cuprizone results in increased expression of CDKN1A mRNA CTD PMID:26577399 , PMID:27523638 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of CDKN1A mRNA CTD PMID:18550754 curcumin multiple interactions ISO RGD:735341 6480464 [Arsenic Trioxide co-treated with Curcumin] results in increased expression of CDKN1A protein more ... CTD PMID:18226269 more ... curcumin multiple interactions EXP 6480464 [Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDKN1A protein], Curcumin inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDKN1A protein] CTD PMID:28681665 curcumin increases expression ISO RGD:735341 6480464 Curcumin results in increased expression of CDKN1A more ... CTD PMID:15713895 more ... curcumin decreases expression ISO RGD:735341 6480464 [Curcumin results in decreased expression of MDM2 protein] which results in decreased expression of CDKN1A mRNA, Curcumin results in decreased expression of CDKN1A protein CTD PMID:17148446 more ... curcumin increases expression ISO RGD:69328 6480464 Curcumin results in increased expression of CDKN1A protein CTD PMID:17602960 , PMID:18316600 curcumin multiple interactions ISO RGD:69328 6480464 Buthionine Sulfoximine inhibits the reaction [Curcumin results in increased expression of CDKN1A protein] CTD PMID:17602960 curcumin increases expression EXP 6480464 Curcumin results in increased expression of CDKN1A, Curcumin results in increased expression of CDKN1A mRNA CTD PMID:15738001 , PMID:25822711 cyanamide multiple interactions ISO RGD:69328 6480464 [Ethanol co-treated with Cyanamide] results in decreased expression of CDKN1A mRNA CTD PMID:12003908 cycloheximide multiple interactions ISO RGD:735341 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Cycloheximide results in decreased expression of CDKN1A protein] more ... CTD PMID:10441511 more ... cycloheximide multiple interactions EXP 6480464 Cycloheximide promotes the reaction [Dexamethasone results in decreased expression of CDKN1A protein], Cycloheximide promotes the reaction [Semaxinib results in increased expression of CDKN1A mRNA] CTD PMID:28424418 , PMID:28940008 cycloheximide decreases expression ISO RGD:735341 6480464 Cycloheximide results in decreased expression of CDKN1A mRNA, Cycloheximide results in decreased expression of CDKN1A protein CTD PMID:24211769 more ... cycloheximide multiple interactions ISO RGD:69328 6480464 Cycloheximide inhibits the reaction [manganese chloride results in increased expression of CDKN1A protein] CTD PMID:22542671 cyclophosphamide increases expression ISO RGD:735341 6480464 Cyclophosphamide results in increased expression of CDKN1A mRNA CTD PMID:21527772 , PMID:29445054 cyclophosphamide increases expression EXP 6480464 Cyclophosphamide results in increased expression of CDKN1A mRNA CTD PMID:15331540 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of CDKN1A mRNA, Cyclosporine results in increased expression of CDKN1A protein CTD PMID:19770486 , PMID:22155090 cyclosporin A increases expression ISO RGD:735341 6480464 Cyclosporine results in increased expression of CDKN1A mRNA, Cyclosporine results in increased expression of CDKN1A protein CTD PMID:20106945 more ... cyclosporin A multiple interactions ISO RGD:735341 6480464 [Cyclosporine co-treated with NGF protein] promotes the reaction [SP1 protein binds to CDKN1A promoter] more ... CTD PMID:24244623 cylindrospermopsin increases expression ISO RGD:735341 6480464 cylindrospermopsin results in increased expression of CDKN1A mRNA CTD PMID:21607682 more ... cylindrospermopsin multiple interactions ISO RGD:735341 6480464 [4 more ... CTD PMID:32244372 cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of CDKN1A mRNA, cypermethrin results in decreased expression of CDKN1A protein CTD PMID:36116546 , PMID:37011868 cypermethrin increases expression ISO RGD:735341 6480464 cypermethrin results in increased expression of CDKN1A mRNA CTD PMID:36063984 cyproconazole increases expression EXP 6480464 cyproconazole results in increased expression of CDKN1A mRNA CTD PMID:28058446 cyproconazole multiple interactions ISO RGD:69328 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in decreased expression of CDKN1A mRNA, [cyproconazole co-treated with epoxiconazole] results in decreased expression of CDKN1A mRNA CTD PMID:29038839 cyproconazole multiple interactions ISO RGD:735341 6480464 [NR1I2 protein co-treated with NR1I3 protein] affects the reaction [cyproconazole results in increased expression of CDKN1A mRNA] CTD PMID:28058446 cytarabine multiple interactions ISO RGD:735341 6480464 [fludarabine co-treated with Cytarabine co-treated with docetaxel] results in increased expression of CDKN1A protein, Caffeine inhibits the reaction [Cytarabine results in increased expression of CDKN1A protein] CTD PMID:17977830 , PMID:9703875 cytarabine increases expression ISO RGD:69328 6480464 Cytarabine results in increased expression of CDKN1A mRNA, Cytarabine results in increased expression of CDKN1A protein CTD PMID:14766721 , PMID:15203180 cytarabine increases expression ISO RGD:735341 6480464 Cytarabine results in increased expression of CDKN1A mRNA, Cytarabine results in increased expression of CDKN1A protein CTD PMID:17977830 , PMID:33770205 cytochalasin B increases expression ISO RGD:735341 6480464 Cytochalasin B results in increased expression of CDKN1A protein CTD PMID:27640744 D-glucose increases expression EXP 6480464 Glucose results in increased expression of CDKN1A mRNA CTD PMID:17178593 D-glucose decreases expression ISO RGD:735341 6480464 Glucose results in decreased expression of CDKN1A protein CTD PMID:33992720 D-glucose increases expression ISO RGD:69328 6480464 Glucose results in increased expression of CDKN1A mRNA, Glucose results in increased expression of CDKN1A protein CTD PMID:22561310 , PMID:27652271 D-glucose increases expression ISO RGD:735341 6480464 Glucose results in increased expression of CDKN1A mRNA, Glucose results in increased expression of CDKN1A protein CTD PMID:27049278 , PMID:35264022 D-glucose multiple interactions ISO RGD:69328 6480464 Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter] more ... CTD PMID:22561310 , PMID:27652271 D-glucose multiple interactions ISO RGD:735341 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA more ... CTD PMID:24451382 more ... dactolisib increases expression ISO RGD:735341 6480464 dactolisib results in increased expression of CDKN1A protein CTD PMID:23651616 daidzein multiple interactions ISO RGD:735341 6480464 daidzein promotes the reaction [CDKN1A protein binds to CDK2 protein], ESR2 affects the reaction [daidzein results in increased expression of CDKN1A] CTD PMID:11322924 , PMID:21161820 daidzein increases expression ISO RGD:735341 6480464 daidzein results in increased expression of CDKN1A CTD PMID:21161820 danazol increases expression ISO RGD:735341 6480464 Danazol results in increased expression of CDKN1A protein CTD PMID:27358234 daunorubicin increases expression ISO RGD:735341 6480464 Daunorubicin results in increased expression of CDKN1A more ... CTD PMID:12112851 more ... DDT decreases expression EXP 6480464 DDT results in decreased expression of CDKN1A mRNA CTD PMID:23684557 DDT decreases expression ISO RGD:735341 6480464 DDT results in decreased expression of CDKN1A mRNA CTD PMID:33728745 DDT multiple interactions EXP 6480464 DDT inhibits the reaction [TRP53 protein binds to CDKN1A promoter], DDT promotes the reaction [ESR1 protein binds to CDKN1A promoter] CTD PMID:23684557 decabromodiphenyl ether decreases expression ISO RGD:69328 6480464 decabromobiphenyl ether results in decreased expression of CDKN1A mRNA CTD PMID:23640034 deguelin decreases expression ISO RGD:735341 6480464 [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CDKN1A protein more ... CTD PMID:19139008 , PMID:25242579 deguelin increases expression ISO RGD:735341 6480464 deguelin results in increased expression of CDKN1A mRNA CTD PMID:29512685 dehydroepiandrosterone increases expression ISO RGD:735341 6480464 Dehydroepiandrosterone results in increased expression of CDKN1A mRNA CTD PMID:15752352 dehydroepiandrosterone increases expression ISO RGD:69328 6480464 Dehydroepiandrosterone results in increased expression of CDKN1A protein CTD PMID:16457693 demethoxycurcumin increases expression ISO RGD:735341 6480464 demethoxycurcumin results in increased expression of CDKN1A mRNA CTD PMID:33582110 deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of CDKN1A mRNA CTD PMID:22454431 deoxynivalenol multiple interactions ISO RGD:735341 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CDKN1A mRNA] more ... CTD PMID:18006205 more ... deoxynivalenol decreases degradation ISO RGD:735341 6480464 deoxynivalenol results in decreased degradation of CDKN1A mRNA CTD PMID:18006205 deoxynivalenol increases expression ISO RGD:735341 6480464 deoxynivalenol results in increased expression of CDKN1A mRNA, deoxynivalenol results in increased expression of CDKN1A protein CTD PMID:18006205 more ... desferrioxamine B increases expression ISO RGD:69328 6480464 Deferoxamine results in increased expression of CDKN1A mRNA, Deferoxamine results in increased expression of CDKN1A protein CTD PMID:10559391 , PMID:16227210 desferrioxamine B multiple interactions ISO RGD:735341 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1A mRNA more ... CTD PMID:33962019 , PMID:35690295 desferrioxamine B decreases expression ISO RGD:735341 6480464 Deferoxamine results in decreased expression of CDKN1A protein CTD PMID:12807743 , PMID:23483119 desferrioxamine B increases expression ISO RGD:735341 6480464 Deferoxamine results in increased expression of CDKN1A mRNA, Deferoxamine results in increased expression of CDKN1A protein CTD PMID:10397746 more ... dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of CDKN1A mRNA, Dexamethasone results in increased expression of CDKN1A protein CTD PMID:18395440 , PMID:21041162 dexamethasone decreases stability EXP 6480464 Dexamethasone results in decreased stability of CDKN1A protein CTD PMID:28940008 dexamethasone multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Dexamethasone results in decreased expression of and affects the localization of CDKN1A protein] more ... CTD PMID:28940008 , PMID:30409764 dexamethasone increases expression ISO RGD:735341 6480464 Dexamethasone results in increased expression of CDKN1A mRNA CTD PMID:22064387 dexamethasone multiple interactions ISO RGD:69328 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of CDKN1A mRNA] CTD PMID:20032058 dexamethasone increases expression ISO RGD:69328 6480464 Dexamethasone results in increased expression of CDKN1A mRNA, Dexamethasone results in increased expression of CDKN1A protein CTD PMID:20032058 , PMID:9442036 dexamethasone multiple interactions ISO RGD:735341 6480464 Dexamethasone inhibits the reaction [CDK2 protein binds to CDKN1A protein] CTD PMID:12800980 diacetylmonoxime decreases expression EXP 6480464 diacetylmonoxime results in decreased expression of CDKN1A protein CTD PMID:15252113 Diallyl sulfide increases expression ISO RGD:735341 6480464 allyl sulfide results in increased expression of CDKN1A mRNA CTD PMID:17937621 , PMID:24650757 diallyl trisulfide increases expression ISO RGD:735341 6480464 diallyl trisulfide results in increased expression of CDKN1A mRNA, diallyl trisulfide results in increased expression of CDKN1A protein CTD PMID:16222732 more ... diallyl trisulfide multiple interactions ISO RGD:735341 6480464 diallyl trisulfide inhibits the reaction [CTNNB1 protein results in decreased expression of CDKN1A protein] CTD PMID:29626521 diamminedichloroplatinum increases expression ISO RGD:735341 6480464 transplatin results in increased expression of CDKN1A mRNA CTD PMID:11099651 diarsenic trioxide increases stability ISO RGD:735341 6480464 Arsenic Trioxide results in increased stability of CDKN1A protein CTD PMID:21278055 diarsenic trioxide increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to Arsenic Trioxide CTD PMID:16283431 , PMID:24801890 diarsenic trioxide increases expression ISO RGD:735341 6480464 Arsenic Trioxide results in increased expression of CDKN1A mRNA, Arsenic Trioxide results in increased expression of CDKN1A protein CTD PMID:10850458 more ... diarsenic trioxide increases sumoylation ISO RGD:735341 6480464 Arsenic Trioxide results in increased sumoylation of CDKN1A protein CTD PMID:28318385 diarsenic trioxide multiple interactions ISO RGD:735341 6480464 1 more ... CTD PMID:10850458 more ... diarsenic trioxide multiple interactions ISO RGD:69328 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein], pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA] CTD PMID:17487067 , PMID:23337567 diarsenic trioxide decreases expression ISO RGD:735341 6480464 Arsenic Trioxide results in decreased expression of CDKN1A mRNA CTD PMID:29159499 diarsenic trioxide affects expression ISO RGD:735341 6480464 Arsenic Trioxide affects the expression of CDKN1A mRNA, Arsenic Trioxide affects the expression of CDKN1A protein CTD PMID:12749819 more ... diarsenic trioxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein] more ... CTD PMID:21565247 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of CDKN1A mRNA, Arsenic Trioxide results in increased expression of CDKN1A protein CTD PMID:15073043 more ... diarsenic trioxide increases expression ISO RGD:69328 6480464 Arsenic Trioxide results in increased expression of CDKN1A mRNA, Arsenic Trioxide results in increased expression of CDKN1A protein CTD PMID:17487067 more ... diarsenic trioxide decreases methylation ISO RGD:735341 6480464 Arsenic Trioxide results in decreased methylation of CDKN1A promoter CTD PMID:29159499 diazene increases expression ISO RGD:735341 6480464 diazene analog results in increased expression of CDKN1A CTD PMID:16061352 diazinon increases methylation ISO RGD:735341 6480464 Diazinon results in increased methylation of CDKN1A gene CTD PMID:22964155 diaziquone multiple interactions ISO RGD:735341 6480464 [NQO1 protein results in increased metabolism of diaziquone] which results in increased expression of CDKN1A mRNA more ... CTD PMID:8943236 , PMID:9343371 diaziquone increases expression ISO RGD:735341 6480464 diaziquone results in increased expression of CDKN1A mRNA CTD PMID:8943236 dibenz[a,h]anthracene increases expression EXP 6480464 1 more ... CTD PMID:26377693 dibenziodolium multiple interactions ISO RGD:735341 6480464 diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein] CTD PMID:15978937 dibenzo[a,l]pyrene increases expression ISO RGD:735341 6480464 dibenzo(a, l)pyrene results in increased expression of CDKN1A mRNA CTD PMID:15735009 , PMID:22409540 dibenzo[a,l]pyrene increases expression EXP 6480464 dibenzo(a, l)pyrene results in increased expression of CDKN1A mRNA CTD PMID:26496743 dibenzo[a,l]pyrene multiple interactions ISO RGD:735341 6480464 [Benzo(a)pyrene co-treated with dibenzo(a, l)pyrene] results in increased expression of CDKN1A mRNA CTD PMID:17690111 dibenzofuran increases expression ISO RGD:69328 6480464 dibenzofuran analog results in increased expression of CDKN1A mRNA CTD PMID:20566336 dibenzofuran multiple interactions ISO RGD:69328 6480464 AHR protein promotes the reaction [dibenzofuran analog results in increased expression of CDKN1A mRNA] CTD PMID:20566336 dibenzoylmethane decreases expression EXP 6480464 dibenzoylmethane results in decreased expression of CDKN1A protein CTD PMID:17942926 dibutyl phthalate increases expression ISO RGD:69328 6480464 Dibutyl Phthalate results in increased expression of CDKN1A mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions ISO RGD:69328 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CDKN1A mRNA CTD PMID:35762964 dibutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:33316053 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of CDKN1A mRNA CTD PMID:23242528 dichlorine increases expression ISO RGD:69328 6480464 Chlorine results in increased expression of CDKN1A mRNA CTD PMID:18636392 dichlorine multiple interactions ISO RGD:69328 6480464 [Ozone co-treated with Chlorine] affects the expression of CDKN1A mRNA CTD PMID:18636392 dichlorvos increases expression ISO RGD:69328 6480464 Dichlorvos results in increased expression of CDKN1A mRNA, Dichlorvos results in increased expression of CDKN1A protein CTD PMID:21813463 , PMID:24369695 dichlorvos multiple interactions ISO RGD:69328 6480464 TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A mRNA], TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A protein] CTD PMID:24369695 dichromium trioxide multiple interactions ISO RGD:735341 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of CDKN1A mRNA CTD PMID:12634122 diclofenac increases expression ISO RGD:735341 6480464 Diclofenac results in increased expression of CDKN1A mRNA CTD PMID:19022234 diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of CDKN1A mRNA CTD PMID:26934552 diclofenac increases expression ISO RGD:69328 6480464 Diclofenac results in increased expression of CDKN1A mRNA CTD PMID:19022234 dicoumarol multiple interactions ISO RGD:735341 6480464 Dicumarol inhibits the reaction [diaziquone results in increased expression of CDKN1A mRNA], Dicumarol inhibits the reaction [RB1CC1 protein results in increased expression of CDKN1A protein] CTD PMID:16061648 , PMID:9343371 dieldrin affects expression ISO RGD:69328 6480464 Dieldrin affects the expression of CDKN1A mRNA CTD PMID:22546817 diethanolamine decreases expression EXP 6480464 diethanolamine results in decreased expression of CDKN1A mRNA CTD PMID:16014740 diethanolamine decreases expression ISO RGD:69328 6480464 diethanolamine results in decreased expression of CDKN1A mRNA CTD PMID:16014740 diethyl maleate increases expression ISO RGD:735341 6480464 diethyl maleate results in increased expression of CDKN1A mRNA, diethyl maleate results in increased expression of CDKN1A protein CTD PMID:11875189 , PMID:27982581 diethyl maleate multiple interactions ISO RGD:735341 6480464 TP53 protein affects the reaction [diethyl maleate results in increased expression of CDKN1A protein] CTD PMID:27982581 diethyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:33316053 diethyl phthalate multiple interactions ISO RGD:69328 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CDKN1A mRNA CTD PMID:35762964 diethylstilbestrol increases expression ISO RGD:69328 6480464 Diethylstilbestrol results in increased expression of CDKN1A mRNA CTD PMID:15890375 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of CDKN1A mRNA CTD PMID:15545218 more ... digitonin decreases expression EXP 6480464 Digitonin results in decreased expression of CDKN1A protein CTD PMID:36030841 digitoxin decreases expression ISO RGD:735341 6480464 Digitoxin analog results in decreased expression of CDKN1A protein, Digitoxin results in decreased expression of CDKN1A protein CTD PMID:22037315 dihydroartemisinin increases expression ISO RGD:735341 6480464 artenimol results in increased expression of CDKN1A mRNA CTD PMID:21547369 dihydrocapsaicin increases expression ISO RGD:735341 6480464 dihydrocapsaicin results in increased expression of CDKN1A protein CTD PMID:19139269 dihydrolipoic acid multiple interactions EXP 6480464 2-phenyl-4 more ... CTD PMID:21462292 dihydrolipoic acid increases expression EXP 6480464 dihydrolipoic acid results in increased expression of CDKN1A mRNA CTD PMID:21462292 dihydroxyacetone decreases expression ISO RGD:735341 6480464 Dihydroxyacetone results in decreased expression of CDKN1A mRNA CTD PMID:32506039 diisobutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:33316053 diisobutyl phthalate multiple interactions ISO RGD:69328 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CDKN1A mRNA CTD PMID:35762964 diisononyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of CDKN1A mRNA] CTD PMID:33316053 diisononyl phthalate multiple interactions ISO RGD:69328 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CDKN1A mRNA CTD PMID:35762964 Dimefox decreases expression ISO RGD:735341 6480464 dimefox results in decreased expression of CDKN1A mRNA CTD PMID:18418871 dimethylarsinic acid decreases expression ISO RGD:69328 6480464 Cacodylic Acid results in decreased expression of CDKN1A mRNA, Cacodylic Acid results in decreased expression of CDKN1A protein CTD PMID:12151359 , PMID:17481689 dimethylarsinic acid multiple interactions ISO RGD:735341 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of CDKN1A mRNA CTD PMID:23192986 dimethylarsinous acid increases expression ISO RGD:735341 6480464 dimethylarsinous acid results in increased expression of CDKN1A mRNA CTD PMID:20886546 dioscin increases expression ISO RGD:735341 6480464 dioscin results in increased expression of CDKN1A mRNA, dioscin results in increased expression of CDKN1A protein CTD PMID:29990575 , PMID:33359023 dioxygen multiple interactions ISO RGD:735341 6480464 4'-O-methylalpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased expression of CDKN1A mRNA] more ... CTD PMID:19091749 more ... dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of CDKN1A mRNA CTD PMID:30529165 dioxygen multiple interactions ISO RGD:69328 6480464 [Valproic Acid co-treated with Oxygen deficiency] results in increased expression of CDKN1A protein, [vorinostat co-treated with Oxygen deficiency] results in increased expression of CDKN1A protein CTD PMID:22711276 dioxygen affects expression EXP 6480464 Oxygen deficiency affects the expression of CDKN1A mRNA CTD PMID:17193925 dioxygen increases expression ISO RGD:735341 6480464 Oxygen deficiency results in increased expression of CDKN1A mRNA, Oxygen deficiency results in increased expression of CDKN1A protein CTD PMID:10951577 more ... dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression ISO RGD:735341 6480464 Antimony Potassium Tartrate results in increased expression of CDKN1A mRNA CTD PMID:17547211 diquat increases expression EXP 6480464 Diquat results in increased expression of CDKN1A mRNA CTD PMID:36851058 disodium selenite multiple interactions ISO RGD:735341 6480464 [Sodium Selenite co-treated with (1 more ... CTD PMID:21515331 , PMID:28757135 disodium selenite increases expression ISO RGD:735341 6480464 Sodium Selenite results in increased expression of CDKN1A mRNA, Sodium Selenite results in increased expression of CDKN1A protein CTD PMID:24383545 , PMID:25204997 divanadium pentaoxide decreases expression ISO RGD:735341 6480464 vanadium pentoxide results in decreased expression of CDKN1A protein CTD PMID:33913241 dorsomorphin multiple interactions ISO RGD:735341 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:23274516 , PMID:27188386 dorsomorphin increases expression ISO RGD:735341 6480464 dorsomorphin results in increased expression of CDKN1A protein CTD PMID:23274516 doxazosin increases expression ISO RGD:735341 6480464 Doxazosin results in increased expression of CDKN1A mRNA CTD PMID:12771931 doxorubicin multiple interactions ISO RGD:735341 6480464 1-phenyl-2-hexadecanoylamino-3-pyrrolidino-1-propanol inhibits the reaction [Doxorubicin results in increased expression of CDKN1A protein] more ... CTD PMID:15601469 more ... doxorubicin multiple interactions ISO RGD:69328 6480464 [Doxorubicin affects the reaction [TP53 protein binds to HSPB1 protein]] which results in increased expression of CDKN1A protein, Fungal Polysaccharides inhibits the reaction [Doxorubicin results in increased expression of CDKN1A mRNA] CTD PMID:18263706 , PMID:27181935 doxorubicin increases expression ISO RGD:69328 6480464 Doxorubicin results in increased expression of CDKN1A mRNA, Doxorubicin results in increased expression of CDKN1A protein CTD PMID:15124910 more ... doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of CDKN1A mRNA, Doxorubicin results in increased expression of CDKN1A protein CTD PMID:16013437 more ... doxorubicin increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to Doxorubicin CTD PMID:15601469 , PMID:22927544 doxorubicin decreases response to substance EXP 6480464 CDKN1A results in decreased susceptibility to Doxorubicin CTD PMID:21920376 doxorubicin increases expression ISO RGD:735341 6480464 Doxorubicin results in increased expression of CDKN1A more ... CTD PMID:12006519 more ... doxorubicin affects expression ISO RGD:69328 6480464 Doxorubicin affects the expression of CDKN1A mRNA CTD PMID:12187937 doxorubicin multiple interactions EXP 6480464 [[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of CDKN1A mRNA more ... CTD PMID:16013437 more ... doxorubicin increases activity ISO RGD:735341 6480464 Doxorubicin results in increased activity of CDKN1A protein CTD PMID:15141020 doxorubicin decreases expression ISO RGD:735341 6480464 Doxorubicin results in decreased expression of CDKN1A protein CTD PMID:14601052 doxorubicin affects expression ISO RGD:735341 6480464 Doxorubicin affects the expression of CDKN1A mRNA, Doxorubicin affects the expression of CDKN1A protein CTD PMID:17893511 more ... doxorubicin affects response to substance ISO RGD:735341 6480464 CDKN1A affects the susceptibility to Doxorubicin CTD PMID:15492826 doxycycline multiple interactions EXP 6480464 Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CDKN1A mRNA] CTD PMID:18089841 Echimidine multiple interactions ISO RGD:735341 6480464 [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of CDKN1A mRNA CTD PMID:33884520 Echimidine increases expression ISO RGD:69328 6480464 echimidine results in increased expression of CDKN1A mRNA CTD PMID:32419051 ellagic acid multiple interactions EXP 6480464 [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9 more ... CTD PMID:20103723 ellagic acid multiple interactions ISO RGD:735341 6480464 [Ellagic Acid co-treated with Quercetin] results in increased expression of CDKN1A mRNA more ... CTD PMID:15735102 ellagic acid increases expression ISO RGD:735341 6480464 Ellagic Acid results in increased expression of CDKN1A protein CTD PMID:23554011 ellipticine increases expression ISO RGD:735341 6480464 ellipticine results in increased expression of CDKN1A protein CTD PMID:29471073 ellipticine multiple interactions ISO RGD:735341 6480464 [ellipticine results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein more ... CTD PMID:29471073 emtricitabine multiple interactions ISO RGD:735341 6480464 [Emtricitabine co-treated with Tenofovir] results in increased expression of CDKN1A protein CTD PMID:31545371 endosulfan increases expression ISO RGD:69328 6480464 Endosulfan results in increased expression of CDKN1A mRNA CTD PMID:29391264 endosulfan increases expression ISO RGD:735341 6480464 Endosulfan results in increased expression of CDKN1A mRNA CTD PMID:29705383 , PMID:30090376 Enterolactone multiple interactions ISO RGD:735341 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of CDKN1A mRNA CTD PMID:19167446 Enterolactone decreases expression ISO RGD:735341 6480464 2, 3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of CDKN1A mRNA CTD PMID:19167446 entinostat multiple interactions ISO RGD:735341 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [entinostat results in increased expression of CDKN1A protein] more ... CTD PMID:18223691 , PMID:25699604 entinostat increases expression EXP 6480464 entinostat results in increased expression of CDKN1A protein CTD PMID:21041383 entinostat decreases expression ISO RGD:735341 6480464 entinostat results in decreased expression of CDKN1A protein CTD PMID:20421217 entinostat increases expression ISO RGD:735341 6480464 entinostat results in increased expression of CDKN1A mRNA, entinostat results in increased expression of CDKN1A protein CTD PMID:18223691 more ... entinostat multiple interactions EXP 6480464 TNFSF10 protein promotes the reaction [entinostat results in increased expression of CDKN1A protein] CTD PMID:21041383 entinostat multiple interactions ISO RGD:69328 6480464 [Azacitidine co-treated with entinostat] results in increased expression of CDKN1A mRNA CTD PMID:21224363 epoxiconazole multiple interactions ISO RGD:69328 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in decreased expression of CDKN1A mRNA, [cyproconazole co-treated with epoxiconazole] results in decreased expression of CDKN1A mRNA CTD PMID:29038839 erlotinib hydrochloride increases expression ISO RGD:735341 6480464 Erlotinib Hydrochloride results in increased expression of CDKN1A mRNA CTD PMID:29274334 erlotinib hydrochloride multiple interactions ISO RGD:735341 6480464 Erlotinib Hydrochloride promotes the reaction [Arsenic Trioxide results in increased expression of CDKN1A mRNA] CTD PMID:29274334 esculetin multiple interactions ISO RGD:69328 6480464 esculetin promotes the reaction [CDKN1A protein binds to CDK2 protein] more ... CTD PMID:21600278 esculetin increases expression ISO RGD:735341 6480464 esculetin results in increased expression of CDKN1A protein CTD PMID:31313495 esculetin increases expression ISO RGD:69328 6480464 esculetin results in increased expression of CDKN1A protein CTD PMID:21600278 estriol increases expression EXP 6480464 Estriol results in increased expression of CDKN1A mRNA CTD PMID:25575267 etacrynic acid increases expression ISO RGD:735341 6480464 Ethacrynic Acid results in increased expression of CDKN1A mRNA CTD PMID:25817893 ethanol affects expression ISO RGD:69328 6480464 Ethanol affects the expression of CDKN1A mRNA CTD PMID:11772933 ethanol increases expression ISO RGD:735341 6480464 Ethanol results in increased expression of CDKN1A mRNA, Ethanol results in increased expression of CDKN1A protein CTD PMID:34192554 , PMID:34405320 ethanol increases expression EXP 6480464 Ethanol results in increased expression of CDKN1A mRNA, Ethanol results in increased expression of CDKN1A protein CTD PMID:34192554 , PMID:34405320 ethanol multiple interactions EXP 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]] more ... CTD PMID:34192554 , PMID:34405320 ethanol decreases expression ISO RGD:69328 6480464 Ethanol results in decreased expression of CDKN1A mRNA CTD PMID:34547370 ethanol affects expression EXP 6480464 Ethanol affects the expression of CDKN1A mRNA CTD PMID:30319688 ethanol multiple interactions ISO RGD:735341 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of CDKN1A mRNA more ... CTD PMID:29432896 more ... ethanol increases expression ISO RGD:69328 6480464 Ethanol results in increased expression of CDKN1A mRNA CTD PMID:11181050 ethanol multiple interactions ISO RGD:69328 6480464 [Ethanol co-treated with Cyanamide] results in decreased expression of CDKN1A mRNA CTD PMID:12003908 ethyl methanesulfonate increases expression ISO RGD:735341 6480464 Ethyl Methanesulfonate results in increased expression of CDKN1A mRNA CTD PMID:23649840 , PMID:24211769 etoposide multiple interactions EXP 6480464 [CDKN2A gene mutant form results in increased expression of CDKN2A protein alternative form] inhibits the reaction [Etoposide results in increased expression of CDKN1A protein], TRP53 affects the reaction [Etoposide results in increased expression of CDKN1A mRNA] CTD PMID:21526190 , PMID:24067374 etoposide increases expression ISO RGD:735341 6480464 Etoposide results in increased expression of CDKN1A mRNA, Etoposide results in increased expression of CDKN1A protein CTD PMID:14601052 more ... etoposide multiple interactions ISO RGD:69328 6480464 cordycepin inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA] more ... CTD PMID:17516866 , PMID:23690541 etoposide increases expression ISO RGD:69328 6480464 Etoposide results in increased expression of CDKN1A mRNA, Etoposide results in increased expression of CDKN1A protein CTD PMID:17516866 , PMID:23690541 etoposide multiple interactions ISO RGD:735341 6480464 [Etoposide results in increased susceptibility to Benzo(a)pyrene] which results in increased expression of CDKN1A protein more ... CTD PMID:21617849 more ... etoposide increases expression EXP 6480464 Etoposide results in increased expression of CDKN1A mRNA, Etoposide results in increased expression of CDKN1A protein CTD PMID:21526190 , PMID:24067374 eugenol multiple interactions EXP 6480464 Eugenol inhibits the reaction [9 more ... CTD PMID:20043298 eugenol multiple interactions ISO RGD:69328 6480464 Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein] CTD PMID:19851710 EUK-134 multiple interactions ISO RGD:735341 6480464 EUK-134 affects the reaction [Vitamin K 3 results in increased expression of CDKN1A protein], EUK-134 inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN1A protein] CTD PMID:25005833 farnesol increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to Farnesol CTD PMID:17138864 farnesol increases expression ISO RGD:735341 6480464 Farnesol results in increased expression of CDKN1A protein CTD PMID:17138864 farnesol multiple interactions ISO RGD:735341 6480464 Farnesol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein] CTD PMID:17138864 farrerol increases expression ISO RGD:735341 6480464 farrerol results in increased expression of CDKN1A mRNA, farrerol results in increased expression of CDKN1A protein CTD PMID:35833306 fenamidone increases expression EXP 6480464 fenamidone results in increased expression of CDKN1A mRNA CTD PMID:27029645 fenbendazole increases expression ISO RGD:69328 6480464 Fenbendazole results in increased expression of CDKN1A mRNA, Fenbendazole results in increased expression of CDKN1A protein CTD PMID:23411599 fenitrothion increases expression ISO RGD:69328 6480464 Fenitrothion results in increased expression of CDKN1A mRNA CTD PMID:33393722 fenitrothion multiple interactions ISO RGD:69328 6480464 [Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [Fenitrothion results in increased expression of CDKN1A mRNA] more ... CTD PMID:33393722 fenofibrate multiple interactions ISO RGD:69328 6480464 [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1A mRNA CTD PMID:18253720 fenofibrate decreases expression ISO RGD:69328 6480464 Fenofibrate results in decreased expression of CDKN1A mRNA CTD PMID:25596134 fenvalerate increases expression ISO RGD:69328 6480464 fenvalerate results in increased expression of CDKN1A mRNA CTD PMID:30307764 ferric ammonium citrate multiple interactions ISO RGD:735341 6480464 ferric ammonium citrate inhibits the reaction [2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein] CTD PMID:12807743 ferric oxide increases expression ISO RGD:69328 6480464 ferric oxide analog results in increased expression of CDKN1A protein CTD PMID:22995439 ferrostatin-1 multiple interactions ISO RGD:69328 6480464 ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein] CTD PMID:33737050 ferulic acid increases expression ISO RGD:69328 6480464 ferulic acid results in increased expression of CDKN1A protein CTD PMID:15363954 ferulic acid increases expression ISO RGD:735341 6480464 ferulic acid results in increased expression of CDKN1A protein CTD PMID:15486966 fisetin multiple interactions ISO RGD:735341 6480464 [Cisplatin co-treated with fisetin] results in increased expression of CDKN1A protein CTD PMID:21216935 fisetin increases expression ISO RGD:735341 6480464 fisetin results in increased expression of CDKN1A protein CTD PMID:21216935 flavanone increases expression ISO RGD:735341 6480464 flavanone results in increased expression of CDKN1A protein CTD PMID:22056764 flavanones multiple interactions ISO RGD:735341 6480464 CDKN1A gene mutant form promotes the reaction [Flavanones results in increased cleavage of CASP7 protein], CDKN1A gene mutant form promotes the reaction [Flavanones results in increased phosphorylation of H2AX protein] CTD PMID:21616090 flavanones decreases response to substance ISO RGD:735341 6480464 CDKN1A protein results in decreased susceptibility to Flavanones CTD PMID:21616090 flavanones increases expression ISO RGD:735341 6480464 Flavanones results in increased expression of CDKN1A protein CTD PMID:21616090 flavokawain B multiple interactions ISO RGD:735341 6480464 [ATG5 protein affects the susceptibility to flavokawain B] which affects the expression of CDKN1A protein, [Chloroquine co-treated with flavokawain B] results in decreased expression of CDKN1A protein CTD PMID:30025493 flavonoids increases expression ISO RGD:69328 6480464 Flavonoids results in increased expression of CDKN1A mRNA CTD PMID:18035473 fludioxonil multiple interactions ISO RGD:735341 6480464 fulvestrant inhibits the reaction [fludioxonil results in decreased expression of CDKN1A protein] CTD PMID:27539251 fludioxonil decreases expression ISO RGD:735341 6480464 fludioxonil results in decreased expression of CDKN1A protein CTD PMID:27539251 fluoranthene multiple interactions ISO RGD:735341 6480464 [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of CDKN1A mRNA CTD PMID:17690111 fluoranthene multiple interactions EXP 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of CDKN1A mRNA, SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of CDKN1A mRNA] CTD PMID:28329830 fluorometholone multiple interactions ISO RGD:735341 6480464 Fluorometholone inhibits the reaction [Glucose results in increased expression of CDKN1A protein] CTD PMID:35264022 fluoxetine multiple interactions ISO RGD:735341 6480464 [Fluoxetine results in decreased activity of CKS1B protein] which results in decreased degradation of CDKN1A protein CTD PMID:18371935 fluoxetine increases expression ISO RGD:735341 6480464 Fluoxetine results in increased expression of CDKN1A mRNA CTD PMID:18836303 fluoxetine affects expression ISO RGD:735341 6480464 Fluoxetine affects the expression of CDKN1A mRNA CTD PMID:18371935 folic acid affects expression ISO RGD:735341 6480464 Folic Acid affects the expression of CDKN1A mRNA, Folic Acid affects the expression of CDKN1A protein CTD PMID:16361273 folic acid increases expression ISO RGD:735341 6480464 Folic Acid results in increased expression of CDKN1A protein CTD PMID:26056802 folic acid multiple interactions ISO RGD:735341 6480464 AG 1879 inhibits the reaction [Folic Acid results in increased expression of CDKN1A protein] more ... CTD PMID:22183962 , PMID:26056802 folic acid multiple interactions EXP 6480464 [1 more ... CTD PMID:20938992 more ... folpet increases expression EXP 6480464 folpet results in increased expression of CDKN1A mRNA CTD PMID:31558096 formaldehyde increases expression ISO RGD:69328 6480464 Formaldehyde results in increased expression of CDKN1A mRNA CTD PMID:12679049 formaldehyde decreases expression ISO RGD:735341 6480464 Formaldehyde results in decreased expression of CDKN1A mRNA, Formaldehyde results in decreased expression of CDKN1A protein CTD PMID:28937961 , PMID:30236600 formaldehyde increases expression ISO RGD:735341 6480464 Formaldehyde results in increased expression of CDKN1A mRNA, Formaldehyde results in increased expression of CDKN1A protein CTD PMID:22525295 , PMID:23649840 fotemustine increases expression ISO RGD:735341 6480464 fotemustine results in increased expression of CDKN1A mRNA CTD PMID:25125662 fucoidan increases expression ISO RGD:735341 6480464 fucoidan results in increased expression of CDKN1A CTD PMID:24333868 fulvestrant multiple interactions ISO RGD:735341 6480464 fulvestrant inhibits the reaction [ESR1 protein binds to CDKN1A promoter] more ... CTD PMID:12473173 more ... fulvestrant affects response to substance ISO RGD:735341 6480464 CDKN1A affects the susceptibility to fulvestrant CTD PMID:24169358 fulvestrant increases expression ISO RGD:735341 6480464 fulvestrant results in increased expression of CDKN1A mRNA CTD PMID:12154049 , PMID:20696891 fumonisin B1 multiple interactions ISO RGD:735341 6480464 [fumonisin B1 results in decreased chemical synthesis of Ceramides] which results in decreased expression of CDKN1A protein CTD PMID:25195822 fumonisin B1 increases expression EXP 6480464 fumonisin B1 results in increased expression of CDKN1A mRNA CTD PMID:16221962 furan multiple interactions EXP 6480464 [Bromodeoxyuridine co-treated with furan] results in increased expression of CDKN1A mRNA CTD PMID:24910943 furan increases expression ISO RGD:69328 6480464 furan results in increased expression of CDKN1A mRNA CTD PMID:20124500 , PMID:26194646 furan increases expression EXP 6480464 furan results in increased expression of CDKN1A mRNA CTD PMID:20194422 more ... furazolidone multiple interactions ISO RGD:735341 6480464 CDKN1A mutant form inhibits the reaction [Furazolidone results in increased expression of HMOX1 protein] more ... CTD PMID:26687534 furazolidone increases expression ISO RGD:735341 6480464 Furazolidone results in increased expression of CDKN1A mRNA CTD PMID:26687534 furazolidone decreases expression ISO RGD:735341 6480464 Furazolidone results in decreased expression of CDKN1A protein CTD PMID:26687534 galangin increases expression ISO RGD:735341 6480464 galangin results in increased expression of CDKN1A protein CTD PMID:25450235 gallic acid increases expression ISO RGD:735341 6480464 Gallic Acid results in increased expression of CDKN1A protein CTD PMID:22245431 gamma-hexachlorocyclohexane increases expression ISO RGD:735341 6480464 Hexachlorocyclohexane results in increased expression of CDKN1A mRNA, Hexachlorocyclohexane results in increased expression of CDKN1A protein CTD PMID:14688026 gamma-hexachlorocyclohexane decreases expression ISO RGD:735341 6480464 Hexachlorocyclohexane results in decreased expression of CDKN1A protein CTD PMID:18174961 gamma-hexachlorocyclohexane multiple interactions ISO RGD:735341 6480464 Hexachlorocyclohexane affects the reaction [Benzo(a)pyrene results in increased expression of CDKN1A mRNA], Hexachlorocyclohexane inhibits the reaction [Estradiol results in increased expression of CDKN1A protein] CTD PMID:18174961 gamma-hexachlorocyclohexane increases expression ISO RGD:69328 6480464 Hexachlorocyclohexane results in increased expression of CDKN1A mRNA CTD PMID:17785943 gamma-tocopherol decreases expression ISO RGD:735341 6480464 gamma-Tocopherol results in decreased expression of CDKN1A protein CTD PMID:12368234 ganglioside GM1 increases expression ISO RGD:69328 6480464 G(M1) Ganglioside results in increased expression of CDKN1A protein CTD PMID:15654767 gefitinib increases expression ISO RGD:735341 6480464 gefitinib results in increased expression of CDKN1A protein CTD PMID:17513607 gefitinib decreases expression ISO RGD:735341 6480464 gefitinib results in decreased expression of CDKN1A protein CTD PMID:28942004 gefitinib multiple interactions ISO RGD:735341 6480464 leptomycin B inhibits the reaction [gefitinib results in decreased expression of CDKN1A protein] CTD PMID:28942004 gemcitabine multiple interactions ISO RGD:735341 6480464 [alvocidib co-treated with Gemcitabine] results in increased expression of CDKN1A protein more ... CTD PMID:15770523 more ... gemcitabine increases expression ISO RGD:735341 6480464 Gemcitabine results in increased expression of CDKN1A mRNA, Gemcitabine results in increased expression of CDKN1A protein CTD PMID:15476743 more ... genistein multiple interactions ISO RGD:735341 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CDKN1A protein] more ... CTD PMID:15896711 more ... genistein multiple interactions ISO RGD:69328 6480464 Genistein inhibits the reaction [bisphenol A results in decreased expression of CDKN1A protein], Genistein inhibits the reaction [bisphenol A results in increased expression of CDKN1A protein] CTD PMID:24884420 genistein increases expression EXP 6480464 Genistein results in increased expression of CDKN1A mRNA, Genistein results in increased expression of CDKN1A protein CTD PMID:26792615 , PMID:31593742 genistein increases expression ISO RGD:69328 6480464 Genistein results in increased expression of CDKN1A mRNA CTD PMID:31201582 genistein decreases expression EXP 6480464 Genistein results in decreased expression of CDKN1A mRNA CTD PMID:21048042 genistein increases expression ISO RGD:735341 6480464 Genistein results in increased expression of CDKN1A more ... CTD PMID:11322924 more ... genistein decreases expression ISO RGD:735341 6480464 Genistein results in decreased expression of CDKN1A mRNA, Genistein results in decreased expression of CDKN1A protein CTD PMID:16474171 , PMID:17051425 gentamycin increases expression ISO RGD:69328 6480464 Gentamicins results in increased expression of CDKN1A mRNA CTD PMID:33387578 geraniol increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to geraniol CTD PMID:17138864 geraniol increases expression ISO RGD:735341 6480464 geraniol results in increased expression of CDKN1A protein CTD PMID:17138864 , PMID:21371438 geraniol multiple interactions ISO RGD:735341 6480464 geraniol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein] CTD PMID:17138864 gingerol decreases expression ISO RGD:735341 6480464 gingerol results in decreased expression of CDKN1A mRNA CTD PMID:28249781 ginsenoside Rd multiple interactions EXP 6480464 staurosporine aglycone inhibits the reaction [ginsenoside Rd results in increased expression of CDKN1A mRNA] CTD PMID:24599032 ginsenoside Rd increases expression EXP 6480464 ginsenoside Rd results in increased expression of CDKN1A mRNA CTD PMID:24599032 ginsenoside Re increases expression EXP 6480464 ginsenoside Re results in increased expression of CDKN1A mRNA CTD PMID:24599032 ginsenoside Rg1 multiple interactions ISO RGD:735341 6480464 ginsenoside Rg1 affects the reaction [tert-Butylhydroperoxide affects the expression of CDKN1A protein], ginsenoside Rg1 promotes the reaction [Doxorubicin results in increased expression of CDKN1A mRNA] CTD PMID:15606011 , PMID:34783124 glafenine increases expression ISO RGD:69328 6480464 Glafenine results in increased expression of CDKN1A mRNA CTD PMID:24136188 gliclazide multiple interactions EXP 6480464 Gliclazide inhibits the reaction [Hydrogen Peroxide results in increased expression of CDKN1A mRNA] CTD PMID:12646174 glucaric acid multiple interactions EXP 6480464 [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 more ... CTD PMID:20103723 , PMID:25478867 glucose increases expression EXP 6480464 Glucose results in increased expression of CDKN1A mRNA CTD PMID:17178593 glucose decreases expression ISO RGD:735341 6480464 Glucose results in decreased expression of CDKN1A protein CTD PMID:33992720 glucose multiple interactions ISO RGD:735341 6480464 [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA more ... CTD PMID:24451382 more ... glucose increases expression ISO RGD:69328 6480464 Glucose results in increased expression of CDKN1A mRNA, Glucose results in increased expression of CDKN1A protein CTD PMID:22561310 , PMID:27652271 glucose increases expression ISO RGD:735341 6480464 Glucose results in increased expression of CDKN1A mRNA, Glucose results in increased expression of CDKN1A protein CTD PMID:27049278 , PMID:35264022 glucose multiple interactions ISO RGD:69328 6480464 Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter] more ... CTD PMID:22561310 , PMID:27652271 glutathione multiple interactions ISO RGD:735341 6480464 Glutathione inhibits the reaction [Doxorubicin results in increased expression of CDKN1A protein] CTD PMID:22927544 glutathione disulfide increases expression ISO RGD:735341 6480464 Glutathione Disulfide results in increased expression of CDKN1A protein CTD PMID:15993333 glycidol increases expression ISO RGD:69328 6480464 glycidol results in increased expression of CDKN1A mRNA CTD PMID:24915197 glycitein multiple interactions ISO RGD:735341 6480464 ESR2 affects the reaction [glycitein results in increased expression of CDKN1A] CTD PMID:21161820 glycitein increases expression ISO RGD:735341 6480464 glycitein results in increased expression of CDKN1A CTD PMID:21161820 glycyrrhizinic acid increases expression ISO RGD:735341 6480464 Glycyrrhizic Acid results in increased expression of CDKN1A mRNA CTD PMID:35844403 glyphosate multiple interactions ISO RGD:69328 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CDKN1A mRNA CTD PMID:33854195 glyphosate decreases methylation ISO RGD:735341 6480464 glyphosate results in decreased methylation of CDKN1A promoter CTD PMID:31751608 glyphosate increases expression ISO RGD:735341 6480464 glyphosate results in increased expression of CDKN1A mRNA, glyphosate results in increased expression of CDKN1A protein CTD PMID:31295307 more ... guggulsterone increases expression ISO RGD:735341 6480464 pregna-4 more ... CTD PMID:17475222 GW 4064 decreases expression ISO RGD:735341 6480464 GW 4064 results in decreased expression of CDKN1A mRNA, GW 4064 results in decreased expression of CDKN1A protein CTD PMID:28496032 Heliotrine increases expression ISO RGD:69328 6480464 heliotrine results in increased expression of CDKN1A mRNA CTD PMID:32419051 hemin increases expression ISO RGD:735341 6480464 Hemin results in increased expression of CDKN1A protein CTD PMID:14647439 hemin multiple interactions ISO RGD:735341 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Hemin results in increased expression of CDKN1A protein], SB 203580 inhibits the reaction [Hemin results in increased expression of CDKN1A protein] CTD PMID:14647439 heparin increases expression ISO RGD:69328 6480464 Heparin results in increased expression of CDKN1A protein CTD PMID:10926548 hesperetin multiple interactions ISO RGD:735341 6480464 hesperetin promotes the reaction [CDK4 protein binds to CDKN1A protein] CTD PMID:17927510 hesperetin increases expression ISO RGD:735341 6480464 hesperetin results in increased expression of CDKN1A, hesperetin results in increased expression of CDKN1A mRNA CTD PMID:17927510 , PMID:25345581 hesperidin multiple interactions ISO RGD:735341 6480464 BIX 02189 promotes the reaction [Hesperidin results in increased expression of CDKN1A mRNA], BIX 02189 promotes the reaction [Hesperidin results in increased expression of CDKN1A protein] CTD PMID:34984768 hesperidin increases expression ISO RGD:735341 6480464 Hesperidin results in increased expression of CDKN1A mRNA, Hesperidin results in increased expression of CDKN1A protein CTD PMID:34984768 hexadecanoic acid multiple interactions ISO RGD:735341 6480464 3-N-1(spermine)-7 more ... CTD PMID:24451382 , PMID:32369900 histamine multiple interactions ISO RGD:735341 6480464 [HRH4 protein results in increased susceptibility to Histamine] which results in increased expression of CDKN1A protein CTD PMID:22363581 hydrogen peroxide increases expression ISO RGD:735341 6480464 [Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein more ... CTD PMID:12414654 more ... hydrogen peroxide affects response to substance ISO RGD:735341 6480464 CDKN1A protein affects the susceptibility to Hydrogen Peroxide CTD PMID:28757460 , PMID:29486183 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of CDKN1A mRNA, Hydrogen Peroxide results in increased expression of CDKN1A protein CTD PMID:12646174 , PMID:21705337 hydrogen peroxide multiple interactions EXP 6480464 [Hydrogen Peroxide co-treated with CAV1 protein] results in increased expression of CDKN1A protein more ... CTD PMID:12646174 more ... hydrogen peroxide multiple interactions ISO RGD:735341 6480464 [Tretinoin co-treated with Hydrogen Peroxide] results in increased expression of CDKN1A protein more ... CTD PMID:15081873 more ... hydrogen sulfide increases expression EXP 6480464 Hydrogen Sulfide results in increased expression of CDKN1A mRNA CTD PMID:31843631 hydroquinone increases expression ISO RGD:735341 6480464 hydroquinone results in increased expression of CDKN1A mRNA, hydroquinone results in increased expression of CDKN1A protein CTD PMID:23416264 , PMID:27515134 hydroquinone multiple interactions ISO RGD:735341 6480464 SIRT1 protein affects the reaction [hydroquinone results in increased expression of CDKN1A protein] CTD PMID:27515134 hydroxamic acid increases expression ISO RGD:735341 6480464 Hydroxamic Acids results in increased expression of CDKN1A protein CTD PMID:27163855 hydroxyurea multiple interactions ISO RGD:735341 6480464 [Valproic Acid co-treated with Hydroxyurea] results in increased expression of CDKN1A mRNA more ... CTD PMID:17653085 hydroxyurea multiple interactions EXP 6480464 TRP53 gene mutant form inhibits the reaction [Hydroxyurea results in increased expression of CDKN1A mRNA] CTD PMID:29228353 hydroxyurea increases expression EXP 6480464 Hydroxyurea results in increased expression of CDKN1A mRNA CTD PMID:27208086 , PMID:29228353 hydroxyurea increases expression ISO RGD:735341 6480464 Hydroxyurea results in increased expression of CDKN1A mRNA, Hydroxyurea results in increased expression of CDKN1A protein CTD PMID:10961388 more ... hydroxyurea increases expression ISO RGD:69328 6480464 Hydroxyurea results in increased expression of CDKN1A protein CTD PMID:15557822 ibuprofen increases expression ISO RGD:69328 6480464 Ibuprofen results in increased expression of CDKN1A mRNA, Ibuprofen results in increased expression of CDKN1A protein CTD PMID:15099639 idarubicin increases expression EXP 6480464 Idarubicin results in increased expression of CDKN1A mRNA CTD PMID:28973540 idarubicin multiple interactions EXP 6480464 Dexrazoxane inhibits the reaction [Idarubicin results in increased expression of CDKN1A mRNA] CTD PMID:28973540 ifosfamide increases expression ISO RGD:735341 6480464 Ifosfamide results in increased expression of CDKN1A mRNA CTD PMID:25596134 imidacloprid multiple interactions ISO RGD:69328 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CDKN1A mRNA CTD PMID:33854195 indirubin-3'-monoxime multiple interactions ISO RGD:735341 6480464 [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN1A mRNA CTD PMID:18958680 indole-3-methanol increases expression ISO RGD:735341 6480464 indole-3-carbinol analog results in increased expression of CDKN1A protein more ... CTD PMID:16082211 more ... indole-3-methanol multiple interactions ISO RGD:69328 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDKN1A mRNA CTD PMID:22129741 indole-3-methanol affects expression ISO RGD:69328 6480464 indole-3-carbinol affects the expression of CDKN1A mRNA, indole-3-carbinol affects the expression of CDKN1A protein CTD PMID:21396975 indometacin increases activity ISO RGD:735341 6480464 Indomethacin results in increased activity of CDKN1A protein CTD PMID:14566837 indometacin increases expression ISO RGD:69328 6480464 Indomethacin results in increased expression of CDKN1A protein CTD PMID:11170841 indometacin increases expression ISO RGD:735341 6480464 Indomethacin results in increased expression of CDKN1A protein CTD PMID:15786552 , PMID:27358234 indometacin multiple interactions ISO RGD:735341 6480464 Indomethacin promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein] CTD PMID:14566837 indoxyl sulfate increases expression ISO RGD:735341 6480464 Indican results in increased expression of CDKN1A protein CTD PMID:29734669 indoxyl sulfate multiple interactions ISO RGD:735341 6480464 Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein] more ... CTD PMID:29734669 inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CDKN1A mRNA CTD PMID:36331819 inuviscolide increases expression ISO RGD:735341 6480464 inuviscolide results in increased expression of CDKN1A protein CTD PMID:17919456 iodoacetic acid increases expression EXP 6480464 Iodoacetic Acid results in increased expression of CDKN1A mRNA CTD PMID:31693920 , PMID:34453833 irbesartan multiple interactions ISO RGD:735341 6480464 Irbesartan inhibits the reaction [KRAS protein mutant form results in increased expression of CDKN1A protein] CTD PMID:33380422 irinotecan multiple interactions ISO RGD:735341 6480464 [Fluorouracil co-treated with Irinotecan co-treated with Vorinostat] results in increased expression of CDKN1A protein CTD PMID:15754201 irinotecan increases expression ISO RGD:735341 6480464 Irinotecan results in increased expression of CDKN1A mRNA, Irinotecan results in increased expression of CDKN1A protein CTD PMID:15754201 more ... irinotecan affects expression ISO RGD:735341 6480464 Irinotecan affects the expression of CDKN1A protein CTD PMID:15132777 iron atom multiple interactions ISO RGD:69328 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CDKN1A mRNA CTD PMID:22198552 iron(0) multiple interactions ISO RGD:69328 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CDKN1A mRNA CTD PMID:22198552 iron(2+) sulfate (anhydrous) increases expression ISO RGD:735341 6480464 ferrous sulfate results in increased expression of CDKN1A mRNA CTD PMID:21540303 iron(III) nitrilotriacetate increases expression ISO RGD:69328 6480464 ferric nitrilotriacetate results in increased expression of CDKN1A mRNA CTD PMID:23208426 isatin multiple interactions ISO RGD:735341 6480464 [Copper binds to Isatin binds to 2-(2-aminoethyl)pyridine] which results in increased expression of CDKN1A protein more ... CTD PMID:17327230 isobutanol multiple interactions ISO RGD:735341 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of CDKN1A mRNA CTD PMID:29432896 isocyanates increases expression EXP 6480464 Isocyanates results in increased expression of CDKN1A protein CTD PMID:20685613 isoflavones increases expression ISO RGD:735341 6480464 Isoflavones results in increased expression of CDKN1A mRNA, Isoflavones results in increased expression of CDKN1A protein CTD PMID:16365062 , PMID:17374662 isoliquiritigenin increases expression EXP 6480464 isoliquiritigenin results in increased expression of CDKN1A mRNA, isoliquiritigenin results in increased expression of CDKN1A protein CTD PMID:27702603 isoprenaline multiple interactions EXP 6480464 Doxycycline inhibits the reaction [Isoproterenol results in increased expression of CDKN1A mRNA] CTD PMID:18089841 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of CDKN1A mRNA CTD PMID:18089841 , PMID:20003209 isoprene decreases expression ISO RGD:735341 6480464 isoprene results in decreased expression of CDKN1A protein CTD PMID:30236600 isopropyl beta-D-thiogalactopyranoside increases expression ISO RGD:735341 6480464 Isopropyl Thiogalactoside results in increased expression of CDKN1A protein CTD PMID:15190207 isotretinoin decreases expression ISO RGD:735341 6480464 Isotretinoin results in decreased expression of CDKN1A mRNA CTD PMID:20436886 isotretinoin multiple interactions ISO RGD:735341 6480464 [LAQ824 co-treated with Isotretinoin] results in increased expression of CDKN1A mRNA, [LAQ824 co-treated with Isotretinoin] results in increased expression of CDKN1A protein CTD PMID:17237267 isotretinoin increases expression ISO RGD:735341 6480464 Isotretinoin results in increased expression of CDKN1A protein CTD PMID:16575387 ivermectin increases expression ISO RGD:735341 6480464 Ivermectin results in increased expression of CDKN1A protein CTD PMID:28811376 ivermectin decreases expression ISO RGD:735341 6480464 Ivermectin results in decreased expression of CDKN1A protein CTD PMID:32959892 kaempferol increases expression ISO RGD:735341 6480464 kaempferol results in increased expression of CDKN1A mRNA, kaempferol results in increased expression of CDKN1A protein CTD PMID:19397994 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of CDKN1A mRNA CTD PMID:25808816 ketoconazole increases expression ISO RGD:69328 6480464 Ketoconazole results in increased expression of CDKN1A mRNA CTD PMID:16483768 more ... kojic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA CTD PMID:17917374 kojic acid multiple interactions ISO RGD:69328 6480464 [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CDKN1A mRNA CTD PMID:18544905 L-ascorbic acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA CTD PMID:17917374 L-ascorbic acid increases expression ISO RGD:69328 6480464 Ascorbic Acid results in increased expression of CDKN1A mRNA CTD PMID:20400526 L-ascorbic acid multiple interactions ISO RGD:69328 6480464 [INS1 protein co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA, Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein] CTD PMID:20067818 , PMID:20400526 L-ascorbic acid multiple interactions ISO RGD:735341 6480464 [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA more ... CTD PMID:20067818 , PMID:20530418 L-methionine multiple interactions EXP 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of CDKN1A mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CDKN1A mRNA CTD PMID:20938992 , PMID:29127188 L-mimosine increases expression ISO RGD:735341 6480464 Mimosine results in increased expression of CDKN1A CTD PMID:10530763 , PMID:10995875 lamivudine decreases expression ISO RGD:735341 6480464 Lamivudine results in decreased expression of CDKN1A mRNA CTD PMID:15784690 lamivudine multiple interactions ISO RGD:735341 6480464 [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1A mRNA CTD PMID:15784690 lanreotide multiple interactions ISO RGD:69328 6480464 lanreotide promotes the reaction [Diethylnitrosamine results in increased expression of CDKN1A mRNA] CTD PMID:19874807 lapatinib multiple interactions ISO RGD:735341 6480464 Lapatinib inhibits the reaction [sodium arsenite results in increased expression of CDKN1A protein] CTD PMID:32890875 Lasiocarpine multiple interactions ISO RGD:735341 6480464 [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of CDKN1A mRNA CTD PMID:33884520 Lasiocarpine increases expression ISO RGD:69328 6480464 lasiocarpine results in increased expression of CDKN1A mRNA CTD PMID:32419051 lead diacetate multiple interactions ISO RGD:735341 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of CDKN1A mRNA CTD PMID:12634122 lead diacetate multiple interactions ISO RGD:69328 6480464 [lead acetate results in increased abundance of Lead] which results in decreased expression of CDKN1A protein CTD PMID:34350654 lead diacetate increases expression ISO RGD:69328 6480464 lead acetate results in increased expression of CDKN1A mRNA CTD PMID:22641619 lead(0) affects expression ISO RGD:735341 6480464 Lead affects the expression of CDKN1A mRNA CTD PMID:28903495 lead(0) multiple interactions ISO RGD:69328 6480464 [lead acetate results in increased abundance of Lead] which results in decreased expression of CDKN1A protein CTD PMID:34350654 leflunomide increases expression ISO RGD:735341 6480464 leflunomide results in increased expression of CDKN1A mRNA CTD PMID:28988120 lenvatinib affects expression ISO RGD:69328 6480464 lenvatinib affects the expression of CDKN1A protein CTD PMID:34019861 leptomycin B increases expression ISO RGD:735341 6480464 leptomycin B results in increased expression of CDKN1A mRNA, leptomycin B results in increased expression of CDKN1A protein CTD PMID:20803015 more ... leptomycin B multiple interactions ISO RGD:735341 6480464 [epigallocatechin gallate co-treated with leptomycin B] results in increased expression of CDKN1A mRNA more ... CTD PMID:20803015 more ... letrozole increases expression ISO RGD:735341 6480464 letrozole results in increased expression of CDKN1A protein CTD PMID:20054642 Leucomalachite green increases expression ISO RGD:69328 6480464 leucomalachite green results in increased expression of CDKN1A protein CTD PMID:26558467 Licochalcone A increases expression ISO RGD:735341 6480464 licochalcone A results in increased expression of CDKN1A mRNA CTD PMID:30055311 Licochalcone B increases expression ISO RGD:735341 6480464 licochalcone B results in increased expression of CDKN1A mRNA CTD PMID:33647349 lidocaine affects expression EXP 6480464 Lidocaine affects the expression of CDKN1A mRNA CTD PMID:18931217 lidocaine increases expression ISO RGD:69328 6480464 Lidocaine results in increased expression of CDKN1A mRNA CTD PMID:35283115 linalool increases expression ISO RGD:735341 6480464 linalool results in increased expression of CDKN1A mRNA CTD PMID:19922762 , PMID:26703569 linuron increases expression ISO RGD:69328 6480464 Linuron results in increased expression of CDKN1A mRNA CTD PMID:28705778 lipopolysaccharide multiple interactions EXP 6480464 Estradiol promotes the reaction [Lipopolysaccharides results in increased expression of CDKN1A mRNA], Lipopolysaccharides inhibits the reaction [Indirubin E804 results in decreased expression of CDKN1A mRNA] CTD PMID:16977382 , PMID:23107598 lipopolysaccharide multiple interactions ISO RGD:735341 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of CDKN1A mRNA CTD PMID:35877022 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of CDKN1A mRNA CTD PMID:16977382 more ... lithium atom multiple interactions EXP 6480464 TP53 affects the reaction [Lithium results in increased expression of CDKN1A protein] CTD PMID:11337498 lithium chloride increases expression ISO RGD:735341 6480464 Lithium Chloride results in increased expression of CDKN1A mRNA, Lithium Chloride results in increased expression of CDKN1A protein CTD PMID:17440966 , PMID:34624459 lithium hydride multiple interactions EXP 6480464 TP53 affects the reaction [Lithium results in increased expression of CDKN1A protein] CTD PMID:11337498 lomustine increases expression ISO RGD:735341 6480464 Lomustine results in increased expression of CDKN1A mRNA, Lomustine results in increased expression of CDKN1A protein CTD PMID:24211769 , PMID:27358234 loperamide increases expression ISO RGD:735341 6480464 Loperamide results in increased expression of CDKN1A mRNA CTD PMID:34719826 loperamide multiple interactions ISO RGD:735341 6480464 Loperamide promotes the reaction [Doxorubicin results in increased expression of CDKN1A mRNA] CTD PMID:34719826 losartan multiple interactions ISO RGD:735341 6480464 Losartan inhibits the reaction [KRAS protein mutant form results in increased expression of CDKN1A protein] CTD PMID:33380422 lovastatin increases expression ISO RGD:735341 6480464 Lovastatin results in increased expression of CDKN1A protein CTD PMID:18034278 lovastatin multiple interactions EXP 6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased expression of CDKN1A mRNA] CTD PMID:22712078 lucanthone increases expression ISO RGD:735341 6480464 Lucanthone results in increased expression of CDKN1A mRNA CTD PMID:21148553 lupeol multiple interactions ISO RGD:735341 6480464 lupeol inhibits the reaction [mancozeb results in increased expression of CDKN1A mRNA] CTD PMID:27235710 luteolin increases expression ISO RGD:735341 6480464 Luteolin results in increased expression of CDKN1A mRNA, Luteolin results in increased expression of CDKN1A protein CTD PMID:11322924 more ... luteolin increases expression EXP 6480464 Luteolin results in increased expression of CDKN1A protein CTD PMID:31288002 luteolin multiple interactions EXP 6480464 Fluorouracil promotes the reaction [Luteolin results in increased expression of CDKN1A protein], Luteolin promotes the reaction [Fluorouracil results in increased expression of CDKN1A protein] CTD PMID:31288002 luteolin affects localization ISO RGD:69328 6480464 Luteolin affects the localization of CDKN1A protein CTD PMID:31201582 luteolin increases expression ISO RGD:69328 6480464 Luteolin results in increased expression of CDKN1A mRNA CTD PMID:31201582 luteolin 7-O-beta-D-glucoside increases expression ISO RGD:735341 6480464 luteolin-7-glucoside results in increased expression of CDKN1A protein CTD PMID:34165247 LY294002 increases expression EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of CDKN1A protein CTD PMID:15695173 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Dexamethasone results in decreased expression of and affects the localization of CDKN1A protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Dexamethasone results in decreased stability of CDKN1A protein] CTD PMID:28940008 LY294002 multiple interactions ISO RGD:735341 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deoxynivalenol results in increased expression of CDKN1A mRNA] more ... CTD PMID:23146690 more ... LY294002 increases expression ISO RGD:735341 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of CDKN1A mRNA, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of CDKN1A protein CTD PMID:15001399 more ... lycopene multiple interactions ISO RGD:735341 6480464 lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein] CTD PMID:16565789 lycorine increases expression ISO RGD:735341 6480464 lycorine results in increased expression of CDKN1A mRNA CTD PMID:23376478 mancozeb multiple interactions ISO RGD:735341 6480464 lupeol inhibits the reaction [mancozeb results in increased expression of CDKN1A mRNA] CTD PMID:27235710 mancozeb increases expression ISO RGD:735341 6480464 mancozeb results in increased expression of CDKN1A mRNA CTD PMID:27235710 maneb multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of CDKN1A mRNA, Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDKN1A mRNA] CTD PMID:23963992 manganese(II) chloride multiple interactions ISO RGD:69328 6480464 Cycloheximide inhibits the reaction [manganese chloride results in increased expression of CDKN1A protein] CTD PMID:22542671 manganese(II) chloride increases expression ISO RGD:69328 6480464 manganese chloride results in increased expression of CDKN1A mRNA, manganese chloride results in increased expression of CDKN1A protein CTD PMID:22542671 , PMID:28801915 manganese(II) chloride affects localization ISO RGD:69328 6480464 manganese chloride affects the localization of CDKN1A protein CTD PMID:22542671 manumycin A increases expression ISO RGD:735341 6480464 manumycin results in increased expression of CDKN1A protein CTD PMID:19409983 manumycin A multiple interactions ISO RGD:735341 6480464 Acetylcysteine inhibits the reaction [manumycin results in decreased expression of CDKN1A protein] CTD PMID:19409983 Maxacalcitol increases expression ISO RGD:735341 6480464 maxacalcitol results in increased expression of CDKN1A protein CTD PMID:16039115 Mecamylamine multiple interactions EXP 6480464 Mecamylamine inhibits the reaction [Nicotine results in increased expression of CDKN1A mRNA], Mecamylamine inhibits the reaction [Nicotine results in increased expression of CDKN1A protein] CTD PMID:32473187 medroxyprogesterone acetate multiple interactions ISO RGD:735341 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CDKN1A mRNA more ... CTD PMID:20823114 , PMID:22534328 MeIQx increases expression ISO RGD:735341 6480464 2-amino-3 more ... CTD PMID:23810796 melatonin increases expression ISO RGD:735341 6480464 Melatonin results in increased expression of CDKN1A protein CTD PMID:12071473 , PMID:18384530 melatonin multiple interactions ISO RGD:735341 6480464 Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA] more ... CTD PMID:29330934 more ... menadione multiple interactions ISO RGD:735341 6480464 [sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1A protein more ... CTD PMID:19082730 , PMID:25005833 menadione increases expression ISO RGD:735341 6480464 Vitamin K 3 results in increased expression of CDKN1A mRNA, Vitamin K 3 results in increased expression of CDKN1A protein CTD PMID:12414654 more ... menaquinone increases expression ISO RGD:735341 6480464 Vitamin K 2 results in increased expression of CDKN1A protein CTD PMID:29432837 mercury dibromide increases expression ISO RGD:735341 6480464 mercuric bromide results in increased expression of CDKN1A mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:735341 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDKN1A mRNA CTD PMID:27188386 mercury dichloride increases expression ISO RGD:69328 6480464 Mercuric Chloride results in increased expression of CDKN1A mRNA CTD PMID:16507785 metformin increases expression ISO RGD:735341 150404268 Metformin increases expression of CDKN1A protein in epithelial cell of alveolus of lung RGD metformin multiple interactions ISO RGD:69328 6480464 Metformin inhibits the reaction [Testosterone results in decreased expression of CDKN1A mRNA] CTD PMID:26492952 metformin increases expression ISO RGD:69328 6480464 Metformin results in increased expression of CDKN1A mRNA CTD PMID:25596134 , PMID:31324951 methamphetamine increases expression ISO RGD:69328 6480464 Methamphetamine results in increased expression of CDKN1A mRNA, Methamphetamine results in increased expression of CDKN1A protein CTD PMID:19564919 , PMID:36914120 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of CDKN1A mRNA, Methamphetamine results in increased expression of CDKN1A protein CTD PMID:36914120 methamphetamine multiple interactions ISO RGD:69328 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of CDKN1A mRNA, GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN1A protein] CTD PMID:19564919 , PMID:36914120 methapyrilene increases expression ISO RGD:69328 6480464 Methapyrilene results in increased expression of CDKN1A mRNA, Methapyrilene results in increased expression of CDKN1A protein CTD PMID:15890375 more ... methimazole increases expression ISO RGD:69328 6480464 Methimazole results in increased expression of CDKN1A mRNA CTD PMID:30047161 methotrexate multiple interactions ISO RGD:735341 6480464 [Methotrexate co-treated with CDKN1A protein] results in decreased expression of BIK mRNA more ... CTD PMID:18483502 more ... methotrexate increases expression ISO RGD:735341 6480464 Methotrexate results in increased expression of CDKN1A mRNA, Methotrexate results in increased expression of CDKN1A protein CTD PMID:17637740 more ... methoxyacetic acid multiple interactions ISO RGD:735341 6480464 [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased expression of CDKN1A protein, withanone inhibits the reaction [methoxyacetic acid results in increased expression of CDKN1A protein] CTD PMID:21573189 , PMID:26006246 methoxyacetic acid increases expression ISO RGD:735341 6480464 methoxyacetic acid results in increased expression of CDKN1A protein CTD PMID:21573189 methoxychlor affects expression ISO RGD:735341 6480464 Methoxychlor affects the expression of CDKN1A mRNA CTD PMID:22307313 methoxychlor multiple interactions ISO RGD:735341 6480464 fulvestrant inhibits the reaction [Methoxychlor results in decreased expression of CDKN1A mRNA] CTD PMID:24835555 methoxychlor decreases expression ISO RGD:735341 6480464 Methoxychlor results in decreased expression of CDKN1A mRNA, Methoxychlor results in decreased expression of CDKN1A protein CTD PMID:24835555 methoxychlor decreases expression ISO RGD:69328 6480464 Methoxychlor results in decreased expression of CDKN1A mRNA CTD PMID:23303685 methyl caffeate increases expression ISO RGD:735341 6480464 methyl caffeate analog results in increased expression of CDKN1A protein CTD PMID:25481497 methyl carbamate decreases expression ISO RGD:735341 6480464 methyl carbamate results in decreased expression of CDKN1A mRNA CTD PMID:29110037 methyl isocyanate affects expression ISO RGD:735341 6480464 methyl isocyanate affects the expression of CDKN1A protein CTD PMID:19513903 methyl methanesulfonate multiple interactions ISO RGD:735341 6480464 Methyl Methanesulfonate inhibits the reaction [TRIM28 protein binds to CDKN1A promoter] more ... CTD PMID:17079232 methyl methanesulfonate increases expression ISO RGD:735341 6480464 Methyl Methanesulfonate results in increased expression of CDKN1A mRNA CTD PMID:21527772 more ... methylarsonic acid decreases expression ISO RGD:69328 6480464 monomethylarsonic acid results in decreased expression of CDKN1A mRNA CTD PMID:17481689 methylarsonic acid multiple interactions ISO RGD:735341 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of CDKN1A mRNA CTD PMID:23192986 methylmercury chloride increases expression ISO RGD:735341 6480464 methylmercuric chloride results in increased expression of CDKN1A mRNA CTD PMID:26272509 , PMID:28001369 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of CDKN1A protein CTD PMID:31706035 methylmercury chloride multiple interactions ISO RGD:735341 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDKN1A mRNA CTD PMID:27188386 methylparaben decreases expression ISO RGD:735341 6480464 methylparaben results in decreased expression of CDKN1A mRNA, methylparaben results in decreased expression of CDKN1A protein CTD PMID:24481588 methylphenidate increases expression ISO RGD:69328 6480464 Methylphenidate results in increased expression of CDKN1A mRNA CTD PMID:32746681 methylseleninic acid multiple interactions ISO RGD:735341 6480464 DDIT3 protein affects the reaction [methylselenic acid results in increased expression of CDKN1A mRNA] more ... CTD PMID:16205645 more ... methylseleninic acid affects expression ISO RGD:69328 6480464 methylselenic acid affects the expression of CDKN1A protein CTD PMID:12017302 methylseleninic acid increases expression ISO RGD:735341 6480464 methylselenic acid results in increased expression of CDKN1A mRNA, methylselenic acid results in increased expression of CDKN1A protein CTD PMID:12517777 more ... methylseleninic acid affects expression ISO RGD:735341 6480464 methylselenic acid affects the expression of CDKN1A mRNA CTD PMID:14617803 microcystin-LR increases expression ISO RGD:735341 6480464 cyanoginosin LR results in increased expression of CDKN1A protein CTD PMID:20421190 microcystin-LR increases expression ISO RGD:69328 6480464 cyanoginosin LR results in increased expression of CDKN1A protein CTD PMID:31157505 microcystin-LR multiple interactions ISO RGD:69328 6480464 pifithrin inhibits the reaction [cyanoginosin LR results in increased expression of CDKN1A protein] CTD PMID:31157505 microcystin-LR decreases expression ISO RGD:735341 6480464 cyanoginosin LR results in decreased expression of CDKN1A protein CTD PMID:33474710 microcystin-LR increases expression EXP 6480464 cyanoginosin LR results in increased expression of CDKN1A mRNA CTD PMID:17654400 mifepristone multiple interactions ISO RGD:735341 6480464 Mifepristone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CDKN1A protein] more ... CTD PMID:17545545 , PMID:22266097 mithramycin multiple interactions ISO RGD:735341 6480464 Plicamycin inhibits the reaction [[Cyclosporine co-treated with NGF protein] results in increased expression of CDKN1A mRNA], Plicamycin inhibits the reaction [SP1 protein binds to CDKN1A promoter] CTD PMID:24244623 mitomycin C multiple interactions ISO RGD:735341 6480464 [Mitomycin co-treated with Resveratrol] results in increased expression of CDKN1A more ... CTD PMID:15905168 more ... mitomycin C increases expression ISO RGD:735341 6480464 Mitomycin results in increased expression of CDKN1A mRNA, Mitomycin results in increased expression of CDKN1A protein CTD PMID:18647660 more ... mitomycin C increases expression EXP 6480464 Mitomycin results in increased expression of CDKN1A mRNA CTD PMID:25270620 ML-7 decreases expression EXP 6480464 ML 7 results in decreased expression of CDKN1A protein CTD PMID:15252113 mono(2-ethylhexyl) phthalate decreases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of CDKN1A mRNA CTD PMID:22401849 mono(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN1A mRNA CTD PMID:31884101 mono(2-ethylhexyl) phthalate multiple interactions ISO RGD:735341 6480464 Selenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein], Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein] CTD PMID:21515331 mono(2-ethylhexyl) phthalate increases activity ISO RGD:735341 6480464 mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein CTD PMID:21515331 monobenzyl phthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN1A mRNA CTD PMID:31884101 monocrotaline multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA, [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein CTD PMID:21224054 monocrotaline multiple interactions ISO RGD:735341 6480464 [CYP3A4 protein results in increased metabolism of Monocrotaline] which results in increased expression of CDKN1A mRNA CTD PMID:33884520 monocrotophos increases expression ISO RGD:69328 6480464 Monocrotophos results in increased expression of CDKN1A mRNA, Monocrotophos results in increased expression of CDKN1A protein CTD PMID:20957986 , PMID:21445290 monoethyl phthalate multiple interactions EXP 6480464 [monoethyl phthalate co-treated with mono-(2-ethylhexyl)phthalate co-treated with mono-isobutyl phthalate co-treated with monoisononylphthalate co-treated with mono-benzyl phthalate] results in increased expression of CDKN1A mRNA CTD PMID:31884101 monosodium L-glutamate multiple interactions EXP 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] affects the expression of CDKN1A mRNA CTD PMID:19001666 morin increases expression ISO RGD:735341 6480464 morin results in increased expression of CDKN1A mRNA CTD PMID:28689916 morphine multiple interactions ISO RGD:735341 6480464 [Morphine results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of CDKN1A protein CTD PMID:12702572 Morroniside increases expression EXP 6480464 morroniside results in increased expression of CDKN1A mRNA CTD PMID:35848187 motexafin gadolinium multiple interactions ISO RGD:735341 6480464 [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA, nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA] CTD PMID:20530418 myricetin increases expression ISO RGD:735341 6480464 myricetin results in increased expression of CDKN1A mRNA, myricetin results in increased expression of CDKN1A protein CTD PMID:19397994 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO RGD:735341 6480464 N more ... CTD PMID:33645215 N-(6-acetamidohexyl)acetamide increases expression ISO RGD:735341 6480464 hexamethylene bisacetamide results in increased expression of CDKN1A mRNA, hexamethylene bisacetamide results in increased expression of CDKN1A protein CTD PMID:10597302 , PMID:17349212 N-(6-acetamidohexyl)acetamide multiple interactions ISO RGD:735341 6480464 [Tretinoin co-treated with hexamethylene bisacetamide] results in increased expression of CDKN1A mRNA CTD PMID:12130515 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO RGD:735341 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TGFB1 protein results in increased expression of CDKN1A mRNA] CTD PMID:16361081 N-acetyl-L-cysteine multiple interactions ISO RGD:735341 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:12208374 more ... N-acetyl-L-cysteine decreases expression ISO RGD:69328 6480464 Acetylcysteine results in decreased expression of CDKN1A mRNA CTD PMID:26332274 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [2 more ... CTD PMID:21462292 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:69328 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDKN1A mRNA more ... CTD PMID:17602960 more ... N-acetyl-L-cysteine increases expression ISO RGD:69328 6480464 Acetylcysteine results in increased expression of CDKN1A protein CTD PMID:17602960 N-ethyl-N-nitrosourea increases expression ISO RGD:69328 6480464 Ethylnitrosourea results in increased expression of CDKN1A mRNA CTD PMID:15954086 N-ethyl-N-nitrosourea multiple interactions EXP 6480464 DICER1 protein affects the reaction [Ethylnitrosourea results in decreased expression of CDKN1A mRNA] CTD PMID:24478143 N-ethyl-N-nitrosourea decreases expression EXP 6480464 Ethylnitrosourea results in decreased expression of CDKN1A mRNA CTD PMID:24478143 N-ethyl-N-nitrosourea increases expression ISO RGD:735341 6480464 Ethylnitrosourea results in increased expression of CDKN1A mRNA CTD PMID:24211769 N-ethyl-N-nitrosourea increases expression EXP 6480464 Ethylnitrosourea results in increased expression of CDKN1A mRNA CTD PMID:19100860 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:735341 6480464 amentoflavone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein] CTD PMID:28185818 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:69328 6480464 ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein] CTD PMID:33737050 N-methyl-4-phenylpyridinium increases expression ISO RGD:69328 6480464 1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A mRNA, 1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein CTD PMID:28801915 , PMID:33737050 N-methyl-4-phenylpyridinium increases expression ISO RGD:735341 6480464 1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A mRNA, 1-Methyl-4-phenylpyridinium results in increased expression of CDKN1A protein CTD PMID:24810058 , PMID:28185818 N-methyl-N'-nitro-N-nitrosoguanidine decreases expression ISO RGD:735341 6480464 Methylnitronitrosoguanidine results in decreased expression of CDKN1A mRNA CTD PMID:12634122 N-methyl-N'-nitro-N-nitrosoguanidine decreases expression ISO RGD:69328 6480464 Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein CTD PMID:19851710 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO RGD:69328 6480464 Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in decreased expression of CDKN1A protein] CTD PMID:19851710 N-methyl-N-nitrosourea increases expression EXP 6480464 Methylnitrosourea results in increased expression of CDKN1A mRNA CTD PMID:18593901 N-methyl-N-nitrosourea increases expression ISO RGD:735341 6480464 Methylnitrosourea results in increased expression of CDKN1A mRNA CTD PMID:29110037 N-methyl-N-nitrosourea increases expression ISO RGD:69328 6480464 Methylnitrosourea results in increased expression of CDKN1A mRNA CTD PMID:28688903 N-methyl-N-nitrosourea decreases expression ISO RGD:69328 6480464 Methylnitrosourea results in decreased expression of CDKN1A protein CTD PMID:15581186 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Cholic Acid] results in decreased expression of CDKN1A protein more ... CTD PMID:17917374 more ... N-nitrosodiethylamine decreases expression ISO RGD:69328 6480464 Diethylnitrosamine results in decreased expression of CDKN1A protein CTD PMID:17582756 , PMID:24012840 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of CDKN1A mRNA CTD PMID:18282651 more ... N-nitrosodiethylamine increases expression ISO RGD:69328 6480464 Diethylnitrosamine results in increased expression of CDKN1A mRNA, Diethylnitrosamine results in increased expression of CDKN1A protein CTD PMID:19418558 more ... N-nitrosodiethylamine multiple interactions ISO RGD:69328 6480464 2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein] more ... CTD PMID:11003613 more ... N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of CDKN1A mRNA, Diethylnitrosamine results in decreased expression of CDKN1A protein CTD PMID:19996281 more ... N-nitrosodimethylamine increases expression ISO RGD:69328 6480464 Dimethylnitrosamine results in increased expression of CDKN1A mRNA CTD PMID:14600272 more ... N-nitrosodimethylamine decreases expression ISO RGD:69328 6480464 Dimethylnitrosamine results in decreased expression of CDKN1A protein CTD PMID:16155410 N-nitrosodimethylamine increases expression ISO RGD:735341 6480464 Dimethylnitrosamine results in increased expression of CDKN1A mRNA CTD PMID:17547211 N-nitrosomorpholine increases expression ISO RGD:69328 6480464 N-nitrosomorpholine results in increased expression of CDKN1A mRNA, N-nitrosomorpholine results in increased expression of CDKN1A protein CTD PMID:10326863 , PMID:19716841 N-tosyl-L-phenylalanyl chloromethyl ketone increases expression ISO RGD:735341 6480464 Tosylphenylalanyl Chloromethyl Ketone results in increased expression of CDKN1A protein CTD PMID:12821135 NAD zwitterion multiple interactions ISO RGD:69328 6480464 NAD inhibits the reaction [Glucose results in increased expression of CDKN1A protein], SIRT1 protein promotes the reaction [NAD inhibits the reaction [Glucose results in increased expression of CDKN1A protein]] CTD PMID:22561310 NAD(+) multiple interactions ISO RGD:69328 6480464 NAD inhibits the reaction [Glucose results in increased expression of CDKN1A protein], SIRT1 protein promotes the reaction [NAD inhibits the reaction [Glucose results in increased expression of CDKN1A protein]] CTD PMID:22561310 naphthalene increases expression EXP 6480464 naphthalene results in increased expression of CDKN1A mRNA CTD PMID:18978301 naphthalenes increases expression ISO RGD:69328 6480464 Naphthalenes results in increased expression of CDKN1A protein CTD PMID:17337753 naringin increases expression ISO RGD:735341 6480464 naringin results in increased expression of CDKN1A mRNA, naringin results in increased expression of CDKN1A protein CTD PMID:18296682 naringin multiple interactions ISO RGD:69328 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of CDKN1A protein] more ... CTD PMID:18951945 naringin multiple interactions ISO RGD:735341 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of CDKN1A protein] more ... CTD PMID:18296682 naringin increases expression ISO RGD:69328 6480464 naringin results in increased expression of CDKN1A mRNA, naringin results in increased expression of CDKN1A protein CTD PMID:18951945 nickel atom multiple interactions ISO RGD:69328 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in increased expression of CDKN1A mRNA, [Nickel co-treated with Iron co-treated with Tungsten] results in increased expression of CDKN1A mRNA CTD PMID:22198552 nickel atom increases expression ISO RGD:735341 6480464 Nickel results in increased expression of CDKN1A mRNA CTD PMID:24068677 nickel atom multiple interactions ISO RGD:735341 6480464 TP53 protein affects the reaction [Nickel results in increased expression of CDKN1A mRNA] CTD PMID:24068677 nickel atom increases expression EXP 6480464 Nickel results in increased expression of CDKN1A mRNA CTD PMID:12540486 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of CDKN1A mRNA CTD PMID:12426141 , PMID:12839937 nickel dichloride affects expression ISO RGD:69328 6480464 nickel chloride affects the expression of CDKN1A mRNA CTD PMID:22546817 nickel dichloride increases expression ISO RGD:735341 6480464 nickel chloride results in increased expression of CDKN1A mRNA, nickel chloride results in increased expression of CDKN1A protein CTD PMID:17547211 more ... nickel dichloride multiple interactions ISO RGD:735341 6480464 HIF1A protein promotes the reaction [nickel chloride results in increased expression of CDKN1A protein] more ... CTD PMID:21466819 more ... nickel subsulfide decreases expression ISO RGD:69328 6480464 nickel subsulfide results in decreased expression of CDKN1A mRNA CTD PMID:24952340 nickel subsulfide affects expression EXP 6480464 nickel subsulfide affects the expression of CDKN1A mRNA CTD PMID:12729255 nickel sulfate increases expression ISO RGD:735341 6480464 nickel sulfate results in increased expression of CDKN1A mRNA CTD PMID:16314067 nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of CDKN1A mRNA CTD PMID:16100012 , PMID:16166746 niclosamide increases expression ISO RGD:735341 6480464 Niclosamide results in increased expression of CDKN1A mRNA CTD PMID:30258081 niclosamide increases expression EXP 6480464 Niclosamide results in increased expression of CDKN1A mRNA CTD PMID:30258081 niclosamide multiple interactions ISO RGD:735341 6480464 TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA], TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA] CTD PMID:30258081 nicotinamide multiple interactions ISO RGD:735341 6480464 Niacinamide inhibits the reaction [tert-Butylhydroperoxide results in increased expression of CDKN1A protein] CTD PMID:12782109 nicotinamide multiple interactions EXP 6480464 [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9 more ... CTD PMID:25478867 nicotinamide increases expression ISO RGD:69328 6480464 Niacinamide results in increased expression of CDKN1A protein CTD PMID:22561310 nicotinamide multiple interactions ISO RGD:69328 6480464 Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]] CTD PMID:22561310 nicotinamide decreases expression ISO RGD:735341 6480464 Niacinamide results in decreased expression of CDKN1A protein CTD PMID:12782109 nicotine decreases expression ISO RGD:735341 6480464 Nicotine results in decreased expression of CDKN1A protein CTD PMID:18805435 , PMID:30272249 nicotine increases expression EXP 6480464 Nicotine results in increased expression of CDKN1A mRNA, Nicotine results in increased expression of CDKN1A protein CTD PMID:31507073 , PMID:32473187 nicotine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN1A mRNA] more ... CTD PMID:32473187 nicotine increases expression ISO RGD:735341 6480464 Nicotine results in increased expression of CDKN1A protein CTD PMID:16011614 , PMID:20727180 nicotine multiple interactions ISO RGD:735341 6480464 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide inhibits the reaction [Nicotine results in decreased expression of CDKN1A protein] more ... CTD PMID:16601104 , PMID:18805435 nicotinic acid multiple interactions ISO RGD:69328 6480464 Etoposide promotes the reaction [Niacin deficiency results in increased expression of CDKN1A protein] CTD PMID:17516866 nicotinic acid increases expression ISO RGD:69328 6480464 Niacin deficiency results in increased expression of CDKN1A protein CTD PMID:17516866 nimesulide increases expression ISO RGD:735341 6480464 nimesulide results in increased expression of CDKN1A mRNA, nimesulide results in increased expression of CDKN1A protein CTD PMID:14567460 , PMID:16376453 nimesulide multiple interactions ISO RGD:735341 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [nimesulide results in increased expression of CDKN1A mRNA] CTD PMID:16376453 nitenpyram increases expression ISO RGD:735341 6480464 nitenpyram results in increased expression of CDKN1A mRNA CTD PMID:35568224 Nodularin decreases expression ISO RGD:735341 6480464 nodularin results in decreased expression of CDKN1A mRNA CTD PMID:30562542 Nonidet P-40 increases expression ISO RGD:735341 6480464 Nonidet P-40 results in increased expression of CDKN1A mRNA CTD PMID:26552463 NS-398 increases expression ISO RGD:735341 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CDKN1A mRNA, N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CDKN1A protein CTD PMID:14567460 , PMID:16376453 NS-398 increases activity ISO RGD:735341 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased activity of CDKN1A protein CTD PMID:14566837 NS-398 multiple interactions ISO RGD:735341 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of CDKN1A mRNA], N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [CDKN1A protein results in decreased activity of CDK2 protein] CTD PMID:14566837 , PMID:16376453 Nutlin-3 multiple interactions ISO RGD:735341 6480464 Cisplatin promotes the reaction [nutlin 3 results in increased expression of CDKN1A mRNA] more ... CTD PMID:16439685 more ... Nutlin-3 increases expression EXP 6480464 nutlin 3 results in increased expression of CDKN1A mRNA CTD PMID:16949053 Nutlin-3 increases expression ISO RGD:735341 6480464 nutlin 3 results in increased expression of CDKN1A mRNA, nutlin 3 results in increased expression of CDKN1A protein CTD PMID:16014563 more ... O-(chloroacetylcarbamoyl)fumagillol increases expression ISO RGD:735341 6480464 O-(chloroacetylcarbamoyl)fumagillol results in increased expression of CDKN1A protein CTD PMID:15276080 O-methyleugenol increases expression EXP 6480464 methyleugenol results in increased expression of CDKN1A mRNA CTD PMID:15618236 O-methyleugenol increases phosphorylation ISO RGD:69328 6480464 methyleugenol results in increased phosphorylation of CDKN1A protein CTD PMID:26011634 O-methyleugenol increases expression ISO RGD:69328 6480464 methyleugenol results in increased expression of CDKN1A mRNA, methyleugenol results in increased expression of CDKN1A protein CTD PMID:23411599 , PMID:26011634 Obacunone increases expression ISO RGD:735341 6480464 obacunone results in increased expression of CDKN1A protein CTD PMID:25592883 ochratoxin A decreases expression ISO RGD:735341 6480464 ochratoxin A results in decreased expression of CDKN1A mRNA, ochratoxin A results in decreased expression of CDKN1A protein CTD PMID:17316727 more ... ochratoxin A increases expression ISO RGD:735341 6480464 ochratoxin A results in increased expression of CDKN1A mRNA CTD PMID:30008028 , PMID:30559759 ochratoxin A multiple interactions EXP 6480464 TRP53 gene mutant form inhibits the reaction [ochratoxin A results in increased expression of CDKN1A mRNA] CTD PMID:25636497 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of CDKN1A mRNA, ochratoxin A results in increased expression of CDKN1A protein CTD PMID:25636497 , PMID:28710020 ochratoxin A increases expression ISO RGD:69328 6480464 ochratoxin A results in increased expression of CDKN1A mRNA, ochratoxin A results in increased expression of CDKN1A protein CTD PMID:16251485 more ... Octicizer increases expression ISO RGD:735341 6480464 2-ethylhexyldiphenylphosphate results in increased expression of CDKN1A mRNA CTD PMID:30981936 oleanolic acid increases expression ISO RGD:69328 6480464 Oleanolic Acid results in increased expression of CDKN1A mRNA CTD PMID:18706400 oleanolic acid increases expression ISO RGD:735341 6480464 Oleanolic Acid results in increased expression of CDKN1A protein CTD PMID:35690101 oleanolic acid multiple interactions EXP 6480464 Oleanolic Acid inhibits the reaction [Cisplatin results in increased expression of CDKN1A protein] CTD PMID:31306688 oleanolic acid decreases expression ISO RGD:735341 6480464 Oleanolic Acid results in decreased expression of CDKN1A protein CTD PMID:22678527 oleic acid multiple interactions ISO RGD:735341 6480464 3-N-1(spermine)-7 more ... CTD PMID:32369900 omeprazole increases expression ISO RGD:735341 6480464 Omeprazole results in increased expression of CDKN1A protein CTD PMID:27358234 omethoate decreases expression ISO RGD:735341 6480464 dimethoxon results in decreased expression of CDKN1A mRNA CTD PMID:28718371 omethoate affects response to substance ISO RGD:735341 6480464 CDKN1A gene SNP affects the susceptibility to dimethoxon CTD PMID:31405322 organoselenium compound multiple interactions ISO RGD:69328 6480464 Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein] CTD PMID:25301743 orlistat increases expression ISO RGD:735341 6480464 Orlistat results in increased expression of CDKN1A protein CTD PMID:30667213 ortho-Aminoazotoluene increases expression EXP 6480464 o-Aminoazotoluene results in increased expression of CDKN1A mRNA CTD PMID:15346788 ouabain decreases expression ISO RGD:735341 6480464 Ouabain results in decreased expression of CDKN1A mRNA, Ouabain results in decreased expression of CDKN1A protein CTD PMID:21215801 , PMID:28795476 ouabain increases expression ISO RGD:735341 6480464 Ouabain results in increased expression of CDKN1A mRNA, Ouabain results in increased expression of CDKN1A protein CTD PMID:20460749 , PMID:31436044 oxaliplatin increases expression ISO RGD:69328 6480464 oxaliplatin results in increased expression of CDKN1A mRNA CTD PMID:25729387 oxaliplatin decreases expression EXP 6480464 Oxaliplatin results in decreased expression of CDKN1A protein CTD PMID:30031110 oxaliplatin multiple interactions ISO RGD:735341 6480464 Caffeine inhibits the reaction [oxaliplatin results in increased expression of CDKN1A protein], TP53 protein promotes the reaction [oxaliplatin results in increased expression of CDKN1A protein] CTD PMID:16227409 , PMID:19735649 oxaliplatin increases expression ISO RGD:735341 6480464 oxaliplatin results in increased expression of CDKN1A mRNA, oxaliplatin results in increased expression of CDKN1A protein CTD PMID:16227409 more ... oxaliplatin multiple interactions ISO RGD:69328 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of CDKN1A mRNA CTD PMID:25729387 oxazepam increases expression EXP 6480464 Oxazepam results in increased expression of CDKN1A mRNA CTD PMID:15618236 oxfendazole increases expression ISO RGD:69328 6480464 oxfendazole results in increased expression of CDKN1A protein CTD PMID:26558467 oxycodone increases expression ISO RGD:69328 6480464 Oxycodone results in increased expression of CDKN1A mRNA CTD PMID:23439660 ozone increases expression EXP 6480464 Ozone results in increased expression of CDKN1A mRNA CTD PMID:17460151 , PMID:20123758 ozone multiple interactions ISO RGD:735341 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CDKN1A mRNA more ... CTD PMID:31476115 , PMID:32699268 ozone increases expression ISO RGD:69328 6480464 Ozone results in increased expression of CDKN1A mRNA CTD PMID:28623178 more ... ozone increases expression ISO RGD:735341 6480464 Ozone results in increased expression of CDKN1A mRNA CTD PMID:28652203 , PMID:31476115 ozone multiple interactions ISO RGD:69328 6480464 [Ozone co-treated with Chlorine] affects the expression of CDKN1A mRNA CTD PMID:18636392 ozone multiple interactions EXP 6480464 [Acetaminophen co-treated with Ozone] results in increased expression of CDKN1A mRNA CTD PMID:20123758 p-chloromercuribenzoic acid increases expression ISO RGD:735341 6480464 p-Chloromercuribenzoic Acid results in increased expression of CDKN1A mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:735341 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDKN1A mRNA CTD PMID:27188386 p-menthan-3-ol decreases expression ISO RGD:735341 6480464 Menthol results in decreased expression of CDKN1A mRNA CTD PMID:26760959 p-tert-Amylphenol decreases expression ISO RGD:735341 6480464 4-tert-octylphenol results in decreased expression of CDKN1A mRNA CTD PMID:24684733 paclitaxel multiple interactions ISO RGD:735341 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of CDKN1A mRNA more ... CTD PMID:16168113 more ... paclitaxel increases expression ISO RGD:735341 6480464 [Paclitaxel results in increased expression of TP53 protein] which results in increased expression of CDKN1A mRNA, Paclitaxel results in increased expression of CDKN1A protein CTD PMID:16601104 more ... paclitaxel decreases expression ISO RGD:735341 6480464 Paclitaxel results in decreased expression of CDKN1A mRNA CTD PMID:24211769 paclitaxel increases expression EXP 6480464 Paclitaxel results in increased expression of CDKN1A mRNA, Paclitaxel results in increased expression of CDKN1A protein CTD PMID:12929121 , PMID:9231689 palbociclib increases expression ISO RGD:735341 6480464 palbociclib results in increased expression of CDKN1A protein CTD PMID:20473330 panaxydol increases expression ISO RGD:735341 6480464 panaxydol results in increased expression of CDKN1A mRNA, panaxydol results in increased expression of CDKN1A protein CTD PMID:19450571 panobinostat increases expression ISO RGD:735341 6480464 panobinostat results in increased expression of CDKN1A protein CTD PMID:18445700 paracetamol multiple interactions EXP 6480464 [Acetaminophen co-treated with Ozone] results in increased expression of CDKN1A mRNA more ... CTD PMID:17585979 more ... paracetamol affects expression ISO RGD:69328 6480464 Acetaminophen affects the expression of CDKN1A mRNA CTD PMID:33387578 paracetamol increases phosphorylation ISO RGD:69328 6480464 Acetaminophen results in increased phosphorylation of CDKN1A protein CTD PMID:26011634 paracetamol increases expression ISO RGD:69328 6480464 Acetaminophen results in increased expression of CDKN1A mRNA, Acetaminophen results in increased expression of CDKN1A protein CTD PMID:23411599 more ... paracetamol increases expression ISO RGD:735341 6480464 Acetaminophen results in increased expression of CDKN1A mRNA CTD PMID:21420995 more ... paracetamol multiple interactions ISO RGD:69328 6480464 Chlormethiazole inhibits the reaction [Acetaminophen results in increased degradation of CDKN1A protein] CTD PMID:16330492 paracetamol decreases expression ISO RGD:69328 6480464 Acetaminophen results in decreased expression of CDKN1A mRNA, Acetaminophen results in decreased expression of CDKN1A protein CTD PMID:16330492 , PMID:30723492 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of CDKN1A mRNA CTD PMID:15606129 , PMID:17562736 paracetamol affects expression ISO RGD:735341 6480464 Acetaminophen affects the expression of CDKN1A mRNA CTD PMID:11896290 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of CDKN1A mRNA, Acetaminophen results in increased expression of CDKN1A protein CTD PMID:11264010 more ... Paraoxon-methyl increases expression ISO RGD:735341 6480464 methylparaoxon results in increased expression of CDKN1A mRNA CTD PMID:18418871 paraquat increases expression EXP 6480464 Paraquat results in increased expression of CDKN1A mRNA, Paraquat results in increased expression of CDKN1A protein CTD PMID:12595580 more ... paraquat increases expression ISO RGD:69328 6480464 Paraquat results in increased expression of CDKN1A mRNA CTD PMID:32680482 paraquat multiple interactions EXP 6480464 [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDKN1A mRNA more ... CTD PMID:23963992 , PMID:28012437 paraquat increases expression ISO RGD:735341 6480464 Paraquat results in increased expression of CDKN1A mRNA CTD PMID:20883675 , PMID:24060684 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of CDKN1A mRNA CTD PMID:21371552 , PMID:31368498 parathion increases expression ISO RGD:735341 6480464 Parathion results in increased expression of CDKN1A mRNA CTD PMID:17622325 parathion-methyl increases expression ISO RGD:735341 6480464 Methyl Parathion results in increased expression of CDKN1A mRNA CTD PMID:18418871 patulin increases expression EXP 6480464 Patulin results in increased expression of CDKN1A protein CTD PMID:19000704 PD 168393 multiple interactions ISO RGD:735341 6480464 [PD168393 co-treated with Paclitaxel] results in increased expression of CDKN1A protein CTD PMID:16413505 pemetrexed multiple interactions ISO RGD:735341 6480464 [Cisplatin co-treated with Pemetrexed co-treated with Valproic Acid] results in increased expression of CDKN1A protein more ... CTD PMID:19351772 pentachlorophenol multiple interactions EXP 6480464 Pentachlorophenol inhibits the reaction [lucidin 3-O-beta-primveroside results in increased expression of CDKN1A mRNA] CTD PMID:30874336 pentobarbital decreases expression ISO RGD:69328 6480464 Pentobarbital results in decreased expression of CDKN1A mRNA CTD PMID:16978161 perfluorobutyric acid increases expression ISO RGD:735341 6480464 perfluorobutyric acid results in increased expression of CDKN1A mRNA CTD PMID:36251517 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of CDKN1A mRNA CTD PMID:26300304 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CDKN1A mRNA CTD PMID:36331819 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:735341 6480464 perfluorooctane sulfonic acid results in decreased expression of CDKN1A protein CTD PMID:29063134 , PMID:32700164 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of CDKN1A mRNA CTD PMID:18467677 perfluorooctanoic acid multiple interactions ISO RGD:735341 6480464 perfluorooctanoic acid inhibits the reaction [Calcitriol results in increased expression of CDKN1A mRNA] CTD PMID:33033332 perfluorooctanoic acid decreases expression ISO RGD:735341 6480464 perfluorooctanoic acid results in decreased expression of CDKN1A protein CTD PMID:32700164 perfluorooctanoic acid increases expression ISO RGD:735341 6480464 perfluorooctanoic acid results in increased expression of CDKN1A mRNA CTD PMID:25868421 more ... perfluorooctanoic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of CDKN1A mRNA] CTD PMID:18467677 pergolide multiple interactions ISO RGD:735341 6480464 Pergolide inhibits the reaction [[Hydrogen Peroxide results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein] CTD PMID:15081873 perifosine multiple interactions ISO RGD:735341 6480464 perifosine inhibits the reaction [Mitomycin results in increased expression of CDKN1A protein] CTD PMID:34624459 perillyl alcohol multiple interactions ISO RGD:735341 6480464 perillyl alcohol promotes the reaction [CDKN1A protein binds to and results in decreased activity of CDK2 protein] CTD PMID:17138864 perillyl alcohol increases response to substance ISO RGD:735341 6480464 CDKN1A protein results in increased susceptibility to perillyl alcohol CTD PMID:17138864 perillyl alcohol increases expression ISO RGD:735341 6480464 perillyl alcohol results in increased expression of CDKN1A protein CTD PMID:17138864 phenethyl caffeate increases expression ISO RGD:735341 6480464 caffeic acid phenethyl ester results in increased expression of CDKN1A protein CTD PMID:16766008 phenethyl caffeate multiple interactions ISO RGD:735341 6480464 [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in increased expression of CDKN1A mRNA more ... CTD PMID:16766008 more ... phenethyl caffeate increases expression ISO RGD:69328 6480464 caffeic acid phenethyl ester results in increased expression of CDKN1A protein CTD PMID:15885897 phenethyl isothiocyanate increases expression ISO RGD:735341 6480464 phenethyl isothiocyanate results in increased expression of CDKN1A mRNA, phenethyl isothiocyanate results in increased expression of CDKN1A protein CTD PMID:17937621 , PMID:26678675 phenformin increases expression ISO RGD:735341 6480464 Phenformin results in increased expression of CDKN1A protein CTD PMID:14623034 phenformin decreases expression ISO RGD:69328 6480464 Phenformin results in decreased expression of CDKN1A mRNA CTD PMID:31324951 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CDKN1A mRNA CTD PMID:19482888 phenobarbital decreases expression ISO RGD:69328 6480464 Phenobarbital results in decreased expression of CDKN1A mRNA CTD PMID:24090815 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of CDKN1A mRNA CTD PMID:23091169 phenobarbital multiple interactions EXP 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CDKN1A mRNA] CTD PMID:19482888 phenylephrine increases expression ISO RGD:735341 6480464 Phenylephrine results in increased expression of CDKN1A mRNA, Phenylephrine results in increased expression of CDKN1A protein CTD PMID:10766810 phenylephrine increases expression ISO RGD:69328 6480464 Phenylephrine results in increased expression of CDKN1A CTD PMID:15603588 phenylephrine increases stability ISO RGD:735341 6480464 Phenylephrine results in increased stability of CDKN1A mRNA CTD PMID:10766810 phenylmercury acetate increases expression ISO RGD:735341 6480464 Phenylmercuric Acetate results in increased expression of CDKN1A mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:735341 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CDKN1A mRNA CTD PMID:27188386 phenytoin decreases expression ISO RGD:735341 6480464 Phenytoin results in decreased expression of CDKN1A mRNA CTD PMID:14741686 phenytoin multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA, [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein CTD PMID:21224054 PhIP increases expression ISO RGD:735341 6480464 2-amino-1-methyl-6-phenylimidazo(4 more ... CTD PMID:11425520 more ... PhIP increases expression ISO RGD:69328 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of CDKN1A mRNA CTD PMID:29877212 phloretin multiple interactions ISO RGD:735341 6480464 [Ruthenium binds to Phloretin] which results in increased expression of CDKN1A protein CTD PMID:34896434 phorbol 12,13-dibutanoate multiple interactions ISO RGD:735341 6480464 Phorbol 12, 13-Dibutyrate inhibits the reaction [alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A protein]] CTD PMID:15014036 phorbol 12,13-dibutanoate increases expression ISO RGD:735341 6480464 Phorbol 12, 13-Dibutyrate results in increased expression of CDKN1A protein CTD PMID:15014036 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:735341 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein] more ... CTD PMID:15976015 more ... phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA CTD PMID:19945525 phorbol 13-acetate 12-myristate increases expression ISO RGD:735341 6480464 Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA, Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein CTD PMID:10910055 more ... phosgene affects expression EXP 6480464 Phosgene affects the expression of CDKN1A mRNA CTD PMID:16300373 phosphatidylcholine multiple interactions ISO RGD:735341 6480464 [rubitecan co-treated with Phosphatidylcholines] results in increased expression of CDKN1A protein CTD PMID:21695227 phosphoramide mustard increases expression ISO RGD:69328 6480464 phosphoramide mustard results in increased expression of CDKN1A mRNA CTD PMID:26708502 , PMID:27888070 pinosylvin increases expression ISO RGD:735341 6480464 pinosylvin results in increased expression of CDKN1A mRNA CTD PMID:23333577 pioglitazone multiple interactions ISO RGD:69328 6480464 pioglitazone inhibits the reaction [2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]], pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein] CTD PMID:17582756 pioglitazone multiple interactions ISO RGD:735341 6480464 Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]] more ... CTD PMID:26643070 , PMID:29734669 pioglitazone decreases expression ISO RGD:735341 6480464 pioglitazone results in decreased expression of CDKN1A protein CTD PMID:15729575 , PMID:26643070 piperine multiple interactions ISO RGD:735341 6480464 [piperine co-treated with Curcumin] results in decreased expression of CDKN1A protein CTD PMID:30935902 piperonyl butoxide increases expression ISO RGD:69328 6480464 Piperonyl Butoxide results in increased expression of CDKN1A mRNA, Piperonyl Butoxide results in increased expression of CDKN1A protein CTD PMID:15890375 , PMID:23411599 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of CDKN1A mRNA CTD PMID:17950772 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of CDKN1A mRNA CTD PMID:16985257 more ... pirinixic acid increases expression ISO RGD:69328 6480464 pirinixic acid results in increased expression of CDKN1A mRNA CTD PMID:15890375 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid co-treated with PPARA] results in increased expression of CDKN1A mRNA, PPARA protein promotes the reaction [pirinixic acid results in increased expression of CDKN1A mRNA] CTD PMID:18467677 more ... piroxicam multiple interactions ISO RGD:735341 6480464 [Cisplatin co-treated with Piroxicam] affects the localization of CDKN1A protein more ... CTD PMID:21858171 piroxicam affects localization ISO RGD:735341 6480464 Piroxicam affects the localization of CDKN1A protein CTD PMID:21858171 platycodin D increases expression ISO RGD:735341 6480464 platycodin D results in increased expression of CDKN1A protein CTD PMID:25431082 , PMID:27432230 plumbagin increases expression ISO RGD:735341 6480464 plumbagin results in increased expression of CDKN1A mRNA CTD PMID:36336213 poly(vinylpyrrolidone) multiple interactions ISO RGD:735341 6480464 [Silver co-treated with Povidone] results in decreased expression of CDKN1A mRNA, [Silver co-treated with Povidone] results in decreased expression of CDKN1A protein CTD PMID:27387714 ponatinib multiple interactions ISO RGD:735341 6480464 (+)-JQ1 compound promotes the reaction [ponatinib results in increased expression of CDKN1A protein], ponatinib promotes the reaction [(+)-JQ1 compound results in increased expression of CDKN1A protein] CTD PMID:25053825 ponatinib increases expression ISO RGD:735341 6480464 ponatinib results in increased expression of CDKN1A protein CTD PMID:25053825 potassium bromate affects expression ISO RGD:69328 6480464 potassium bromate affects the expression of CDKN1A mRNA, potassium bromate affects the expression of CDKN1A protein CTD PMID:25015661 potassium bromate increases expression ISO RGD:69328 6480464 potassium bromate results in increased expression of CDKN1A mRNA, potassium bromate results in increased expression of CDKN1A protein CTD PMID:20067818 more ... potassium bromate increases expression ISO RGD:735341 6480464 potassium bromate results in increased expression of CDKN1A mRNA, potassium bromate results in increased expression of CDKN1A protein CTD PMID:20067818 more ... potassium bromate multiple interactions ISO RGD:735341 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein], Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein] CTD PMID:20067818 potassium bromate multiple interactions ISO RGD:69328 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein] more ... CTD PMID:20067818 , PMID:25015661 potassium bromate affects methylation ISO RGD:69328 6480464 potassium bromate affects the methylation of CDKN1A gene CTD PMID:25015661 potassium dichromate increases expression ISO RGD:735341 6480464 Potassium Dichromate results in increased expression of CDKN1A mRNA CTD PMID:17547211 , PMID:18332044 pravastatin multiple interactions ISO RGD:735341 6480464 Pravastatin inhibits the reaction [Benzo(a)pyrene results in decreased degradation of CDKN1A protein], Pravastatin inhibits the reaction [Fluorouracil results in decreased degradation of CDKN1A protein] CTD PMID:15625077 prednisone increases expression ISO RGD:735341 6480464 Prednisone results in increased expression of CDKN1A protein CTD PMID:15034294 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of CDKN1A mRNA CTD PMID:28903501 probenecid multiple interactions ISO RGD:735341 6480464 Probenecid promotes the reaction [10-nitro-oleic acid results in increased expression of CDKN1A protein] CTD PMID:29158255 prochloraz decreases expression ISO RGD:69328 6480464 prochloraz results in decreased expression of CDKN1A mRNA CTD PMID:29038839 prochloraz multiple interactions ISO RGD:69328 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in decreased expression of CDKN1A mRNA CTD PMID:29038839 progesterone multiple interactions ISO RGD:735341 6480464 Progesterone promotes the reaction [CDK2 protein binds to CDKN1A protein] more ... CTD PMID:18850315 progesterone increases expression ISO RGD:735341 6480464 Progesterone results in increased expression of CDKN1A mRNA, Progesterone results in increased expression of CDKN1A protein CTD PMID:18045962 , PMID:18850315 promethazine increases expression ISO RGD:69328 6480464 Promethazine results in increased expression of CDKN1A protein CTD PMID:26558467 promethazine increases phosphorylation ISO RGD:69328 6480464 Promethazine results in increased phosphorylation of CDKN1A protein CTD PMID:26011634 promethazine decreases expression ISO RGD:69328 6480464 Promethazine results in decreased expression of CDKN1A mRNA CTD PMID:26011634 , PMID:26558467 propylparaben increases expression EXP 6480464 propylparaben results in increased expression of CDKN1A mRNA CTD PMID:31306770 propylparaben decreases expression ISO RGD:735341 6480464 propylparaben results in decreased expression of CDKN1A mRNA, propylparaben results in decreased expression of CDKN1A protein CTD PMID:24481588 protoporphyrin multiple interactions ISO RGD:69328 6480464 protoporphyrin IX inhibits the reaction [[Sulfasalazine results in increased expression of HMOX1 protein] which results in increased expression of CDKN1A protein] CTD PMID:19234301 pterostilbene increases expression ISO RGD:735341 6480464 pterostilbene results in increased expression of CDKN1A protein CTD PMID:23313376 pterostilbene multiple interactions ISO RGD:735341 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]] more ... CTD PMID:34405320 pterostilbene multiple interactions EXP 6480464 CCN1 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of CDKN1A protein]] more ... CTD PMID:34405320 PX-866 multiple interactions ISO RGD:735341 6480464 [Raloxifene Hydrochloride co-treated with PX-866] results in increased expression of CDKN1A mRNA CTD PMID:27017931 pyrrolidine dithiocarbamate multiple interactions ISO RGD:69328 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1A protein], SB 203580 inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein] CTD PMID:14603533 , PMID:15048878 pyrrolidine dithiocarbamate multiple interactions ISO RGD:735341 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in decreased expression of CDKN1A mRNA] CTD PMID:31048002 pyrrolidine dithiocarbamate increases expression ISO RGD:69328 6480464 pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein CTD PMID:14603533 quartz decreases expression ISO RGD:735341 6480464 Quartz results in decreased expression of CDKN1A mRNA CTD PMID:27917503 quercetin increases expression ISO RGD:735341 6480464 Quercetin metabolite results in increased expression of CDKN1A protein more ... CTD PMID:11322924 more ... quercetin multiple interactions ISO RGD:735341 6480464 [bicalutamide co-treated with Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein more ... CTD PMID:11322924 more ... quercetin increases expression ISO RGD:69328 6480464 Quercetin results in increased expression of CDKN1A mRNA CTD PMID:14757127 quercetin multiple interactions EXP 6480464 [Curcumin co-treated with Quercetin] inhibits the reaction [Benzo(a)pyrene results in decreased expression of CDKN1A protein] more ... CTD PMID:18813348 more ... quercetin increases stability ISO RGD:735341 6480464 Quercetin results in increased stability of CDKN1A protein CTD PMID:12934110 quercetin affects expression ISO RGD:735341 6480464 Quercetin affects the expression of CDKN1A, Quercetin affects the expression of CDKN1A mRNA CTD PMID:16059641 , PMID:32530119 quinacrine decreases expression ISO RGD:735341 6480464 Quinacrine results in decreased expression of CDKN1A mRNA CTD PMID:32910239 quinidine increases expression ISO RGD:735341 6480464 Quinidine results in increased expression of CDKN1A protein CTD PMID:12243503 quinolin-8-ol increases expression ISO RGD:735341 6480464 Oxyquinoline results in increased expression of CDKN1A mRNA CTD PMID:21632981 quinoline increases expression ISO RGD:735341 6480464 [quinoline analog results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein, quinoline analog results in increased expression of CDKN1A protein CTD PMID:18645022 quizartinib multiple interactions ISO RGD:735341 6480464 (+)-JQ1 compound promotes the reaction [quizartinib results in increased expression of CDKN1A protein] more ... CTD PMID:25053825 , PMID:34665271 quizartinib decreases expression ISO RGD:735341 6480464 quizartinib results in decreased expression of CDKN1A protein CTD PMID:34665271 quizartinib increases expression ISO RGD:735341 6480464 quizartinib results in increased expression of CDKN1A protein CTD PMID:25053825 raloxifene multiple interactions ISO RGD:735341 6480464 [Raloxifene Hydrochloride co-treated with PX-866] results in increased expression of CDKN1A mRNA CTD PMID:27017931 raloxifene increases expression ISO RGD:735341 6480464 Raloxifene Hydrochloride results in increased expression of CDKN1A mRNA, Raloxifene Hydrochloride results in increased expression of CDKN1A protein CTD PMID:12154049 , PMID:16497877 raloxifene multiple interactions ISO RGD:69328 6480464 [Raloxifene Hydrochloride co-treated with Bexarotene] affects the reaction [Azoxymethane affects the expression of CDKN1A protein] CTD PMID:24080207 resveratrol multiple interactions ISO RGD:735341 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol results in increased expression of CDKN1A mRNA] more ... CTD PMID:11889192 more ... resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of CDKN1A mRNA, resveratrol results in decreased expression of CDKN1A protein CTD PMID:23293221 more ... resveratrol increases expression ISO RGD:69328 6480464 Resveratrol results in increased expression of CDKN1A mRNA CTD PMID:20797428 , PMID:33775663 resveratrol multiple interactions ISO RGD:69328 6480464 Resveratrol inhibits the reaction [Cadmium Chloride results in increased expression of CDKN1A protein] more ... CTD PMID:20797428 more ... resveratrol increases expression EXP 6480464 resveratrol results in increased expression of CDKN1A mRNA, resveratrol results in increased expression of CDKN1A protein CTD PMID:15122319 more ... resveratrol affects expression EXP 6480464 resveratrol affects the expression of CDKN1A protein CTD PMID:16369916 resveratrol decreases expression ISO RGD:735341 6480464 resveratrol results in decreased expression of CDKN1A, resveratrol results in decreased expression of CDKN1A mRNA CTD PMID:15583814 , PMID:19167446 resveratrol increases activity ISO RGD:735341 6480464 resveratrol results in increased activity of CDKN1A protein CTD PMID:20028382 , PMID:21740780 resveratrol increases expression ISO RGD:735341 6480464 Resveratrol analog results in increased expression of CDKN1A protein more ... CTD PMID:11889192 more ... resveratrol multiple interactions EXP 6480464 [resveratrol co-treated with Dietary Fats] results in increased expression of CDKN1A protein more ... CTD PMID:20103723 , PMID:26223300 riddelliine multiple interactions ISO RGD:735341 6480464 [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of CDKN1A mRNA CTD PMID:33884520 rifampicin multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA, [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein CTD PMID:21224054 ritonavir multiple interactions ISO RGD:735341 6480464 manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Ritonavir results in increased expression of CDKN1A protein] CTD PMID:20884875 ritonavir increases expression ISO RGD:735341 6480464 Ritonavir results in increased expression of CDKN1A mRNA, Ritonavir results in increased expression of CDKN1A protein CTD PMID:19386116 , PMID:20884875 romidepsin multiple interactions ISO RGD:735341 6480464 alvocidib inhibits the reaction [romidepsin results in increased expression of CDKN1A promoter] more ... CTD PMID:15014036 more ... romidepsin increases expression ISO RGD:735341 6480464 romidepsin results in increased expression of CDKN1A mRNA more ... CTD PMID:15014036 more ... rotenone increases expression ISO RGD:735341 6480464 Rotenone results in increased expression of CDKN1A protein CTD PMID:21223980 , PMID:32949572 rotenone affects expression ISO RGD:69328 6480464 Rotenone affects the expression of CDKN1A mRNA CTD PMID:28374803 rotenone multiple interactions ISO RGD:735341 6480464 [PSME4 protein affects the susceptibility to Rotenone] which results in decreased expression of CDKN1A mRNA, Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of CDKN1A mRNA] CTD PMID:19091749 , PMID:32368861 rottlerin multiple interactions ISO RGD:735341 6480464 rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein] CTD PMID:15976015 rubitecan increases expression ISO RGD:735341 6480464 rubitecan results in increased expression of CDKN1A protein CTD PMID:21695227 rubitecan multiple interactions ISO RGD:735341 6480464 [rubitecan co-treated with Phosphatidylcholines] results in increased expression of CDKN1A protein CTD PMID:21695227 ruthenium atom multiple interactions ISO RGD:735341 6480464 [Ruthenium binds to Phloretin] which results in increased expression of CDKN1A protein CTD PMID:34896434 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO RGD:69328 6480464 Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of CDKN1A protein], Buthionine Sulfoximine inhibits the reaction [Curcumin results in increased expression of CDKN1A protein] CTD PMID:17602960 Salinomycin increases expression ISO RGD:735341 6480464 salinomycin results in increased expression of CDKN1A mRNA CTD PMID:34806536 , PMID:35914560 Salinomycin multiple interactions ISO RGD:735341 6480464 [salinomycin co-treated with Calcitriol] results in increased expression of CDKN1A mRNA CTD PMID:35914560 salubrinal multiple interactions ISO RGD:69328 6480464 salubrinal inhibits the reaction [Etoposide results in increased expression of CDKN1A mRNA] CTD PMID:23690541 salvianolic acid B multiple interactions ISO RGD:735341 6480464 salvianolic acid B affects the reaction [TGFB1 protein affects the reaction [SMAD3 protein mutant form affects the expression of CDKN1A protein]] CTD PMID:33290806 salvianolic acid B multiple interactions EXP 6480464 salvianolic acid B inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein], salvianolic acid B inhibits the reaction [SMAD3 protein modified form affects the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]] CTD PMID:33290806 sanguinarine increases expression EXP 6480464 sanguinarine results in increased expression of CDKN1A protein CTD PMID:15981203 sapropterin multiple interactions ISO RGD:735341 6480464 sapropterin inhibits the reaction [Methotrexate results in increased expression of CDKN1A protein] CTD PMID:22183962 SB 203580 multiple interactions ISO RGD:735341 6480464 SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1A protein] more ... CTD PMID:14647439 more ... SB 203580 multiple interactions ISO RGD:69328 6480464 SB 203580 inhibits the reaction [esculetin results in increased expression of CDKN1A protein], SB 203580 inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein] CTD PMID:14603533 , PMID:21600278 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [[1-methylanthracene co-treated with fluoranthene] results in increased expression of CDKN1A mRNA] more ... CTD PMID:11807808 more ... SB 431542 multiple interactions ISO RGD:69328 6480464 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Carbofuran results in increased expression of CDKN1A protein] CTD PMID:28982980 SB 431542 multiple interactions ISO RGD:735341 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SCH 23390 increases expression ISO RGD:69328 6480464 SCH 23390 results in increased expression of CDKN1A mRNA CTD PMID:19564919 SCH 23390 multiple interactions ISO RGD:69328 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of CDKN1A mRNA CTD PMID:19564919 Se-methyl-L-selenocysteine increases expression ISO RGD:735341 6480464 selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein CTD PMID:25321483 Se-methyl-L-selenocysteine multiple interactions ISO RGD:735341 6480464 [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein CTD PMID:25321483 Se-methylselenocysteine increases expression ISO RGD:735341 6480464 selenomethylselenocysteine metabolite results in increased expression of CDKN1A protein CTD PMID:25321483 Se-methylselenocysteine multiple interactions ISO RGD:735341 6480464 [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of CDKN1A protein CTD PMID:25321483 selenomethionine multiple interactions ISO RGD:735341 6480464 Selenomethionine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein] CTD PMID:21515331 selumetinib multiple interactions ISO RGD:735341 6480464 AZD 6244 promotes the reaction [decitabine results in increased expression of CDKN1A] CTD PMID:19422044 senecionine increases expression ISO RGD:69328 6480464 senecionine results in increased expression of CDKN1A mRNA CTD PMID:32419051 senecionine increases expression EXP 6480464 senecionine results in increased expression of CDKN1A protein CTD PMID:35357534 Senkirkine increases expression ISO RGD:69328 6480464 senkirkine results in increased expression of CDKN1A mRNA CTD PMID:32419051 sevoflurane multiple interactions ISO RGD:69328 6480464 Roscovitine inhibits the reaction [Sevoflurane results in increased expression of CDKN1A protein] CTD PMID:33548343 sevoflurane increases expression ISO RGD:69328 6480464 Sevoflurane results in increased expression of CDKN1A protein CTD PMID:33548343 shikimic acid decreases expression ISO RGD:735341 6480464 Shikimic Acid results in decreased expression of CDKN1A mRNA, Shikimic Acid results in decreased expression of CDKN1A protein CTD PMID:31048002 shikimic acid multiple interactions ISO RGD:735341 6480464 MIR300 mRNA affects the reaction [Shikimic Acid results in decreased expression of CDKN1A protein], pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in decreased expression of CDKN1A mRNA] CTD PMID:31048002 Shikonin increases expression ISO RGD:735341 6480464 shikonin results in increased expression of CDKN1A protein CTD PMID:28684144 Shikonin increases expression ISO RGD:69328 6480464 shikonin results in increased expression of CDKN1A protein CTD PMID:16061028 silibinin multiple interactions ISO RGD:735341 6480464 [Silybin co-treated with Arsenic] results in increased expression of CDKN1A protein, benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of CDKN1A protein] CTD PMID:16777994 , PMID:25868784 silibinin increases cleavage ISO RGD:735341 6480464 Silybin results in increased cleavage of CDKN1A protein CTD PMID:16777994 silicon dioxide decreases expression ISO RGD:735341 6480464 Silicon Dioxide results in decreased expression of CDKN1A mRNA CTD PMID:27917503 silicon dioxide multiple interactions ISO RGD:735341 6480464 [BMI1 protein co-treated with Silicon Dioxide] results in decreased expression of CDKN1A protein CTD PMID:35288261 silicon dioxide increases expression ISO RGD:69328 6480464 Silicon Dioxide results in increased expression of CDKN1A mRNA CTD PMID:32721576 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of CDKN1A mRNA CTD PMID:19073995 silicon dioxide increases expression ISO RGD:735341 6480464 Silicon Dioxide analog results in increased expression of CDKN1A mRNA, Silicon Dioxide results in increased expression of CDKN1A protein CTD PMID:23806026 more ... silver atom increases expression ISO RGD:735341 6480464 Silver analog results in increased expression of CDKN1A mRNA, Silver results in increased expression of CDKN1A protein CTD PMID:22546375 more ... silver atom increases expression EXP 6480464 Silver results in increased expression of CDKN1A mRNA CTD PMID:27131904 silver atom multiple interactions ISO RGD:735341 6480464 [Silver co-treated with Povidone] results in decreased expression of CDKN1A mRNA more ... CTD PMID:22546375 , PMID:27387714 silver(0) increases expression ISO RGD:735341 6480464 Silver analog results in increased expression of CDKN1A mRNA, Silver results in increased expression of CDKN1A protein CTD PMID:22546375 more ... silver(0) increases expression EXP 6480464 Silver results in increased expression of CDKN1A mRNA CTD PMID:27131904 silver(0) multiple interactions ISO RGD:735341 6480464 [Silver co-treated with Povidone] results in decreased expression of CDKN1A mRNA more ... CTD PMID:22546375 , PMID:27387714 simvastatin multiple interactions ISO RGD:735341 6480464 [Simvastatin results in decreased degradation of CDKN1A protein] which results in decreased activity of CDK2 protein more ... CTD PMID:15625077 more ... simvastatin increases expression ISO RGD:735341 6480464 Simvastatin results in increased expression of CDKN1A mRNA, Simvastatin results in increased expression of CDKN1A protein CTD PMID:17428261 more ... simvastatin increases expression ISO RGD:69328 6480464 Simvastatin results in increased expression of CDKN1A protein CTD PMID:18804536 sirolimus multiple interactions ISO RGD:735341 6480464 [(+)-JQ1 compound co-treated with Sirolimus] results in increased expression of CDKN1A mRNA more ... CTD PMID:12417722 more ... sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [arsenite results in increased expression of CDKN1A protein] CTD PMID:23396362 sirolimus decreases expression ISO RGD:69328 6480464 Sirolimus results in decreased expression of CDKN1A protein CTD PMID:22561310 sirolimus increases expression ISO RGD:735341 6480464 Sirolimus results in increased expression of CDKN1A mRNA, Sirolimus results in increased expression of CDKN1A protein CTD PMID:19764996 , PMID:21528311 sirolimus multiple interactions ISO RGD:69328 6480464 Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]] more ... CTD PMID:19105244 , PMID:22561310 sirtinol increases expression ISO RGD:735341 6480464 sirtinol results in increased expression of CDKN1A mRNA, sirtinol results in increased expression of CDKN1A protein CTD PMID:22495798 sirtinol multiple interactions ISO RGD:735341 6480464 sirtinol promotes the reaction [cudraflavone B results in increased expression of CDKN1A protein] CTD PMID:23881456 sodium arsenite multiple interactions ISO RGD:735341 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of CDKN1A mRNA more ... CTD PMID:11507245 more ... sodium arsenite increases phosphorylation ISO RGD:735341 6480464 sodium arsenite results in increased phosphorylation of CDKN1A protein CTD PMID:28586017 sodium arsenite affects expression ISO RGD:735341 6480464 sodium arsenite affects the expression of CDKN1A protein CTD PMID:30123091 sodium arsenite increases activity EXP 6480464 sodium arsenite results in increased activity of CDKN1A protein CTD PMID:11807808 sodium arsenite increases expression ISO RGD:735341 6480464 sodium arsenite results in increased expression of CDKN1A mRNA, sodium arsenite results in increased expression of CDKN1A protein CTD PMID:10910055 more ... sodium arsenite decreases expression ISO RGD:735341 6480464 sodium arsenite results in decreased expression of CDKN1A mRNA, sodium arsenite results in decreased expression of CDKN1A protein CTD PMID:20036271 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of CDKN1A mRNA, sodium arsenite results in increased expression of CDKN1A protein CTD PMID:11807808 more ... sodium arsenite increases expression ISO RGD:69328 6480464 sodium arsenite results in increased expression of CDKN1A protein CTD PMID:16797887 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CDKN1A mRNA CTD PMID:11812925 sodium arsenite decreases expression ISO RGD:69328 6480464 sodium arsenite results in decreased expression of CDKN1A mRNA, sodium arsenite results in decreased expression of CDKN1A protein CTD PMID:16876216 sodium arsenite multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [sodium arsenite results in increased expression of CDKN1A protein] more ... CTD PMID:11807808 more ... sodium arsenite affects response to substance ISO RGD:735341 6480464 CDKN1A protein affects the susceptibility to sodium arsenite CTD PMID:20000476 sodium azide multiple interactions ISO RGD:735341 6480464 Sodium Azide inhibits the reaction [2-butylamino-2-demethoxy-hypocrellin B results in increased expression of CDKN1A mRNA] CTD PMID:17045927 sodium chloride decreases expression ISO RGD:735341 6480464 Sodium Chloride results in decreased expression of CDKN1A mRNA CTD PMID:24211769 sodium chromate increases expression ISO RGD:735341 6480464 sodium chromate(VI) results in increased expression of CDKN1A mRNA CTD PMID:16283527 sodium dichromate affects expression ISO RGD:735341 6480464 sodium bichromate affects the expression of CDKN1A protein CTD PMID:26091798 sodium dichromate multiple interactions ISO RGD:735341 6480464 FBP1 protein inhibits the reaction [sodium bichromate results in increased expression of CDKN1A protein] CTD PMID:28624442 sodium dichromate increases expression ISO RGD:735341 6480464 sodium bichromate results in increased expression of CDKN1A mRNA, sodium bichromate results in increased expression of CDKN1A protein CTD PMID:26091798 , PMID:28624442 sodium dichromate increases expression ISO RGD:69328 6480464 sodium bichromate results in increased expression of CDKN1A mRNA CTD PMID:25993096 sodium fluoride increases expression ISO RGD:735341 6480464 Sodium Fluoride results in increased expression of CDKN1A mRNA, Sodium Fluoride results in increased expression of CDKN1A protein CTD PMID:22525295 sodium fluoride increases methylation ISO RGD:735341 6480464 Sodium Fluoride results in increased methylation of CDKN1A promoter CTD PMID:31669217 sodium fluoride multiple interactions ISO RGD:735341 6480464 Decitabine inhibits the reaction [Sodium Fluoride results in decreased expression of CDKN1A mRNA] more ... CTD PMID:31669217 sodium fluoride multiple interactions EXP 6480464 SRT1720 affects the reaction [Sodium Fluoride affects the expression of CDKN1A protein] CTD PMID:30738887 sodium fluoride affects expression EXP 6480464 Sodium Fluoride affects the expression of CDKN1A protein CTD PMID:30738887 sodium fluoride decreases expression ISO RGD:735341 6480464 Sodium Fluoride results in decreased expression of CDKN1A mRNA, Sodium Fluoride results in decreased expression of CDKN1A protein CTD PMID:31669217 Sodium salicylate decreases activity ISO RGD:735341 6480464 Sodium Salicylate results in decreased activity of CDKN1A protein CTD PMID:15190207 sodium tungstate decreases expression ISO RGD:735341 6480464 sodium tungstate(VI) results in decreased expression of CDKN1A mRNA CTD PMID:26164860 Soman increases expression ISO RGD:69328 6480464 Soman results in increased expression of CDKN1A mRNA CTD PMID:19281266 sorafenib decreases expression EXP 6480464 sorafenib results in decreased expression of CDKN1A protein CTD PMID:19139124 sotorasib multiple interactions ISO RGD:735341 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of CDKN1A mRNA CTD PMID:36139627 staurosporine multiple interactions ISO RGD:735341 6480464 Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein] CTD PMID:15978937 stavudine affects expression EXP 6480464 Stavudine affects the expression of CDKN1A protein CTD PMID:18389896 sterigmatocystin decreases expression ISO RGD:69328 6480464 Sterigmatocystin results in decreased expression of CDKN1A mRNA CTD PMID:34126181 streptozocin multiple interactions EXP 6480464 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA] more ... CTD PMID:19496084 more ... streptozocin multiple interactions ISO RGD:69328 6480464 Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein], Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter] CTD PMID:25301743 , PMID:27652271 streptozocin increases expression ISO RGD:69328 6480464 Streptozocin results in increased expression of CDKN1A mRNA, Streptozocin results in increased expression of CDKN1A protein CTD PMID:25301743 , PMID:27652271 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of CDKN1A, Streptozocin results in increased expression of CDKN1A mRNA CTD PMID:19496084 more ... styrene oxide affects expression ISO RGD:735341 6480464 styrene oxide affects the expression of CDKN1A mRNA CTD PMID:11230554 succimer multiple interactions EXP 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of CDKN1A mRNA, [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of CDKN1A mRNA CTD PMID:21641980 , PMID:26378955 sulfadimethoxine increases expression ISO RGD:69328 6480464 Sulfadimethoxine results in increased expression of CDKN1A protein CTD PMID:23535288 sulfasalazine multiple interactions ISO RGD:69328 6480464 protoporphyrin IX inhibits the reaction [[Sulfasalazine results in increased expression of HMOX1 protein] which results in increased expression of CDKN1A protein] CTD PMID:19234301 sulfasalazine increases expression ISO RGD:69328 6480464 [Sulfasalazine results in increased expression of HMOX1 protein] which results in increased expression of CDKN1A protein CTD PMID:19234301 sulfonyldimethane multiple interactions ISO RGD:735341 6480464 [dimethyl sulfone co-treated with Doxorubicin] affects the expression of CDKN1A mRNA, dimethyl sulfone affects the reaction [Doxorubicin results in increased expression of CDKN1A mRNA] CTD PMID:32562081 sulfonyldimethane affects expression ISO RGD:735341 6480464 dimethyl sulfone affects the expression of CDKN1A mRNA CTD PMID:32562081 sulforaphane increases expression ISO RGD:735341 6480464 sulforaphane results in increased expression of CDKN1A mRNA, sulforaphane results in increased expression of CDKN1A protein CTD PMID:15231455 more ... sulindac multiple interactions ISO RGD:735341 6480464 [Sulindac co-treated with epigallocatechin gallate] results in increased expression of CDKN1A mRNA more ... CTD PMID:12628509 more ... sulindac increases expression EXP 6480464 Sulindac results in increased expression of CDKN1A mRNA, Sulindac results in increased expression of CDKN1A protein CTD PMID:15688007 more ... sulindac multiple interactions ISO RGD:69328 6480464 [Azoxymethane co-treated with Sulindac] results in increased expression of CDKN1A protein CTD PMID:18644992 sulindac increases response to substance EXP 6480464 CDKN1A protein results in increased susceptibility to Sulindac CTD PMID:11507085 , PMID:15688007 sulindac increases expression ISO RGD:735341 6480464 Sulindac results in increased expression of CDKN1A mRNA, Sulindac results in increased expression of CDKN1A protein CTD PMID:11507085 more ... sulindac increases activity ISO RGD:735341 6480464 Sulindac results in increased activity of CDKN1A protein CTD PMID:14566837 sulindac decreases activity ISO RGD:735341 6480464 Sulindac results in decreased activity of CDKN1A protein CTD PMID:15190207 sulindac sulfide increases expression ISO RGD:735341 6480464 sulindac sulfide results in increased expression of CDKN1A mRNA, sulindac sulfide results in increased expression of CDKN1A protein CTD PMID:15767558 more ... sulindac sulfide multiple interactions ISO RGD:735341 6480464 PPARD protein inhibits the reaction [sulindac sulfide results in increased expression of CDKN1A mRNA], PPARG protein promotes the reaction [sulindac sulfide results in increased expression of CDKN1A mRNA] CTD PMID:16091736 sulindac sulfide affects activity EXP 6480464 sulindac sulfide affects the activity of CDKN1A protein CTD PMID:15694660 sulindac sulfone increases expression ISO RGD:735341 6480464 sulindac sulfone results in increased expression of CDKN1A mRNA, sulindac sulfone results in increased expression of CDKN1A protein CTD PMID:18593937 sunitinib increases expression ISO RGD:735341 6480464 Sunitinib results in increased expression of CDKN1A mRNA CTD PMID:31533062 T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of CDKN1A mRNA CTD PMID:22454431 T-2 toxin increases expression ISO RGD:69328 6480464 T-2 Toxin results in increased expression of CDKN1A mRNA, T-2 Toxin results in increased expression of CDKN1A protein CTD PMID:29567467 tacrine increases expression ISO RGD:735341 6480464 Tacrine results in increased expression of CDKN1A protein CTD PMID:27358234 taiwanin C increases expression EXP 6480464 taiwanin C results in increased expression of CDKN1A protein CTD PMID:30884126 tamibarotene increases expression ISO RGD:735341 6480464 tamibarotene results in increased expression of CDKN1A mRNA CTD PMID:17229644 tamoxifen multiple interactions ISO RGD:735341 6480464 [Tamoxifen co-treated with FTI 277] promotes the reaction [CDKN1A protein binds to [CCNE1 protein binds to CDK2 protein]] more ... CTD PMID:12866041 more ... tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of CDKN1A mRNA CTD PMID:17555576 tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of CDKN1A mRNA CTD PMID:20937368 tamoxifen increases expression ISO RGD:735341 6480464 Tamoxifen results in increased expression of CDKN1A mRNA, Tamoxifen results in increased expression of CDKN1A protein CTD PMID:20549698 more ... Tanshinone I increases expression ISO RGD:735341 6480464 tanshinone results in increased expression of CDKN1A mRNA CTD PMID:15849732 temozolomide multiple interactions EXP 6480464 [temozolomide co-treated with O(6)-benzylguanine] results in increased expression of CDKN1A protein, TRP53 protein affects the reaction [[temozolomide co-treated with O(6)-benzylguanine] results in increased expression of CDKN1A protein] CTD PMID:20980775 temozolomide decreases expression ISO RGD:735341 6480464 Temozolomide results in decreased expression of CDKN1A mRNA CTD PMID:31758290 temozolomide increases expression ISO RGD:735341 6480464 temozolomide results in increased expression of CDKN1A protein CTD PMID:16193384 temozolomide multiple interactions ISO RGD:735341 6480464 [temozolomide co-treated with O(6)-benzylguanine] affects the localization of CDKN1A protein, [temozolomide co-treated with O(6)-benzylguanine] results in increased expression of CDKN1A protein CTD PMID:20980775 Temsirolimus multiple interactions ISO RGD:735341 6480464 [S 1 (combination) co-treated with temsirolimus] results in increased expression of CDKN1A protein more ... CTD PMID:19764996 Temsirolimus increases expression ISO RGD:735341 6480464 temsirolimus results in increased expression of CDKN1A mRNA CTD PMID:19764996 teniposide increases expression ISO RGD:735341 6480464 Teniposide results in increased expression of CDKN1A mRNA, Teniposide results in increased expression of CDKN1A protein CTD PMID:25914138 tenofovir disoproxil fumarate increases expression ISO RGD:735341 6480464 Tenofovir results in increased expression of CDKN1A protein CTD PMID:31545371 tenofovir disoproxil fumarate multiple interactions ISO RGD:735341 6480464 [Emtricitabine co-treated with Tenofovir] results in increased expression of CDKN1A protein CTD PMID:31545371 Terfenadine increases expression ISO RGD:735341 6480464 Terfenadine results in increased expression of CDKN1A protein CTD PMID:12244568 teriflunomide increases expression ISO RGD:735341 6480464 teriflunomide results in increased expression of CDKN1A protein CTD PMID:12181422 tert-butyl hydroperoxide increases expression ISO RGD:735341 6480464 tert-Butylhydroperoxide results in increased expression of CDKN1A mRNA, tert-Butylhydroperoxide results in increased expression of CDKN1A protein CTD PMID:12414654 more ... tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of CDKN1A mRNA, tert-Butylhydroperoxide results in increased expression of CDKN1A protein CTD PMID:18619952 tert-butyl hydroperoxide multiple interactions ISO RGD:735341 6480464 [Deferoxamine co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1A mRNA more ... CTD PMID:12782109 more ... testosterone decreases expression EXP 6480464 Testosterone deficiency results in decreased expression of CDKN1A mRNA, Testosterone results in decreased expression of CDKN1A mRNA CTD PMID:22138414 , PMID:33848595 testosterone decreases expression ISO RGD:735341 6480464 Testosterone results in decreased expression of CDKN1A mRNA CTD PMID:33359661 testosterone decreases expression ISO RGD:69328 6480464 Testosterone results in decreased expression of CDKN1A mRNA CTD PMID:23500659 more ... testosterone multiple interactions EXP 6480464 1 more ... CTD PMID:24769335 , PMID:33848595 testosterone multiple interactions ISO RGD:69328 6480464 chrysin inhibits the reaction [Testosterone results in decreased expression of CDKN1A mRNA] more ... CTD PMID:20032058 more ... testosterone increases expression EXP 6480464 Testosterone results in increased expression of CDKN1A mRNA CTD PMID:15788153 tetrachloromethane multiple interactions EXP 6480464 [HTS 466284 co-treated with Carbon Tetrachloride] results in increased expression of CDKN1A protein more ... CTD PMID:12759355 , PMID:25566828 tetrachloromethane multiple interactions ISO RGD:69328 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of CDKN1A mRNA] CTD PMID:31150632 tetrachloromethane increases expression ISO RGD:69328 6480464 Carbon Tetrachloride results in increased expression of CDKN1A mRNA CTD PMID:31150632 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of CDKN1A mRNA, Carbon Tetrachloride results in increased expression of CDKN1A protein CTD PMID:12759355 more ... tetrachloromethane decreases expression ISO RGD:69328 6480464 Carbon Tetrachloride results in decreased expression of CDKN1A mRNA CTD PMID:17256749 tetraphene increases expression ISO RGD:735341 6480464 benz(a)anthracene results in increased expression of CDKN1A mRNA CTD PMID:22236718 tetraphene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CDKN1A mRNA CTD PMID:27858113 tetraphene decreases expression EXP 6480464 benz(a)anthracene results in decreased expression of CDKN1A mRNA CTD PMID:26377693 tetrathiomolybdate(2-) increases expression ISO RGD:735341 6480464 tetrathiomolybdate analog results in increased expression of CDKN1A protein CTD PMID:19323979 thapsigargin increases expression ISO RGD:735341 6480464 Thapsigargin results in increased expression of CDKN1A mRNA CTD PMID:29453283 , PMID:33770205 theaflavin multiple interactions EXP 6480464 [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9 more ... CTD PMID:23717041 thiabendazole multiple interactions ISO RGD:69328 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CDKN1A mRNA CTD PMID:33854195 thioacetamide increases expression ISO RGD:69328 6480464 Thioacetamide results in increased expression of CDKN1A mRNA, Thioacetamide results in increased expression of CDKN1A protein CTD PMID:22659510 more ... thioacetamide increases phosphorylation ISO RGD:69328 6480464 Thioacetamide results in increased phosphorylation of CDKN1A protein CTD PMID:26011634 thiophenes multiple interactions ISO RGD:735341 6480464 Thiophenes analog promotes the reaction [Tretinoin results in increased expression of CDKN1A protein] CTD PMID:16140954 thioridazine increases expression ISO RGD:735341 6480464 Thioridazine results in increased expression of CDKN1A protein CTD PMID:21035837 thiostrepton increases expression ISO RGD:735341 6480464 Thiostrepton results in increased expression of CDKN1A mRNA CTD PMID:22321511 thymoquinone multiple interactions ISO RGD:69328 6480464 thymoquinone inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein] CTD PMID:24012840 thymoquinone multiple interactions ISO RGD:735341 6480464 [Benzo(a)pyrene co-treated with thymoquinone] results in increased expression of CDKN1A mRNA CTD PMID:24289642 tirapazamine increases expression ISO RGD:735341 6480464 tirapazamine results in increased expression of CDKN1A CTD PMID:15814660 Tiron multiple interactions ISO RGD:735341 6480464 1 more ... CTD PMID:22532027 titanium dioxide increases expression ISO RGD:735341 6480464 titanium dioxide results in increased expression of CDKN1A mRNA CTD PMID:21067279 titanium dioxide decreases expression ISO RGD:69328 6480464 titanium dioxide results in decreased expression of CDKN1A mRNA CTD PMID:30012374 titanium dioxide decreases expression ISO RGD:735341 6480464 titanium dioxide results in decreased expression of CDKN1A mRNA, titanium dioxide results in decreased expression of CDKN1A protein CTD PMID:30910687 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of CDKN1A mRNA CTD PMID:23409001 more ... tolbutamide multiple interactions ISO RGD:69328 6480464 GJA1 promotes the reaction [Tolbutamide results in increased expression of CDKN1A protein] CTD PMID:16718685 tolbutamide increases expression ISO RGD:69328 6480464 Tolbutamide results in increased expression of CDKN1A protein CTD PMID:16718685 toluene 2,4-diisocyanate increases expression EXP 6480464 Toluene 2, 4-Diisocyanate results in increased expression of CDKN1A mRNA CTD PMID:21404309 Tomentosin increases expression ISO RGD:735341 6480464 tomentosin results in increased expression of CDKN1A protein CTD PMID:17919456 topotecan multiple interactions ISO RGD:69328 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of CDKN1A mRNA CTD PMID:25729387 topotecan increases expression ISO RGD:735341 6480464 Topotecan results in increased expression of CDKN1A mRNA, Topotecan results in increased expression of CDKN1A protein CTD PMID:23376119 , PMID:25667043 topotecan multiple interactions ISO RGD:735341 6480464 [N-(oxo-5 more ... CTD 
