Gene: SLC18A3 (solute carrier family 18 member A3) Homo sapiens
Symbol: SLC18A3
Name: solute carrier family 18 member A3
Description: This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CMS21; MGC12716; OTTHUMP00000019582; solute carrier family 18 (vesicular acetylcholine transporter), member 3; solute carrier family 18 (vesicular acetylcholine), member 3; solute carrier family 18 member 3; solute carrier family 18, member 3; VACHT; vesicular acetylcholine transporter
Mus musculus (house mouse) : Slc18a3 (solute carrier family 18 (vesicular monoamine), member 3)  MGI  AGR
Rattus norvegicus (Norway rat) : Slc18a3 (solute carrier family 18 member A3)  AGR
Chinchilla lanigera (long-tailed chinchilla) : Slc18a3 (solute carrier family 18 member A3)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC18A3 (solute carrier family 18 member A3)
Canis lupus familiaris (dog) : SLC18A3 (solute carrier family 18 member A3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc18a3 (solute carrier family 18 member A3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381049,610,301 - 49,612,720 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371050,818,347 - 50,820,766 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361050,488,353 - 50,490,772 (+)NCBINCBI36hg18NCBI36
Build 341050,488,352 - 50,490,771NCBI
Celera1044,404,433 - 44,406,852 (+)NCBI
Cytogenetic Map10q11.23NCBI
HuRef1045,083,115 - 45,085,534 (+)NCBIHuRef
CHM1_11051,100,431 - 51,102,850 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC18A3
AGR Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732691
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2017-12-26
Status: ACTIVE