Akr7a5 Mouse (+)-schisandrin B multiple interactions ISO Akr7a2 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AKR7A2 mRNA] CTD PMID:31150632 Akr7a5 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 o and p'-DDT affects the expression of AKR7A2 mRNA CTD PMID:17984292 Akr7a5 Mouse 1,2-dimethylhydrazine multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of AKR7A5 mRNA] CTD PMID:22206623 Akr7a5 Mouse 1,2-dimethylhydrazine increases expression EXP 6480464 1 and 2-Dimethylhydrazine results in increased expression of AKR7A5 mRNA CTD PMID:22206623 Akr7a5 Mouse 1,2-naphthoquinone increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of 1 and 2-naphthoquinone CTD PMID:10510318 Akr7a5 Mouse 14-Deoxy-11,12-didehydroandrographolide decreases expression ISO AKR7A2 (Homo sapiens) 6480464 14-deoxy-11 and 12-didehydroandrographolide results in decreased expression of AKR7A2 mRNA CTD PMID:22101062 Akr7a5 Mouse 16-Ketoestrone increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of 16-ketoestrone CTD PMID:10510318 Akr7a5 Mouse 17alpha-ethynylestradiol increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of AKR7A5 mRNA CTD PMID:16926038 Akr7a5 Mouse 17beta-estradiol multiple interactions ISO Akr7a2 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of AKR7A2 mRNA CTD PMID:26496021 Akr7a5 Mouse 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 2 more ... CTD PMID:21394737 more ... Akr7a5 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of AKR7A2 mRNA CTD PMID:18796159 and PMID:33387578 Akr7a5 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR7A2 mRNA CTD PMID:32109520 and PMID:34747641 Akr7a5 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of AKR7A5 mRNA CTD PMID:21570461 Akr7a5 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR7A5 mRNA CTD PMID:19465110 Akr7a5 Mouse 2,4,6-trinitrotoluene affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Trinitrotoluene affects the expression of AKR7A2 mRNA CTD PMID:21346803 Akr7a5 Mouse 2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 2 more ... CTD PMID:19954255 Akr7a5 Mouse 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression EXP 6480464 2 more ... CTD PMID:38648751 Akr7a5 Mouse 2,6-dimethoxyphenol multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [pyrogallol 1 and 3-dimethyl ether co-treated with Furaldehyde] results in increased expression of and affects the localization of AKR7A2 protein CTD PMID:38598786 Akr7a5 Mouse 2-methylcholine affects expression ISO AKR7A2 (Homo sapiens) 6480464 beta-methylcholine affects the expression of AKR7A2 mRNA CTD PMID:21179406 Akr7a5 Mouse 2-nitrobenzaldehyde increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of 2-nitrobenzaldehyde CTD PMID:10510318 Akr7a5 Mouse 2-nitrobenzaldehyde affects reduction EXP 6480464 2-nitrobenzaldehyde affects the reduction of AKR7A5 protein CTD PMID:12604212 Akr7a5 Mouse 3,3',5,5'-tetrabromobisphenol A decreases expression ISO AKR7A2 (Homo sapiens) 6480464 tetrabromobisphenol A results in decreased expression of AKR7A2 protein CTD PMID:31675489 Akr7a5 Mouse 3,4-methylenedioxymethamphetamine decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of AKR7A2 mRNA CTD PMID:30071829 Akr7a5 Mouse 3-chloropropane-1,2-diol decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in decreased expression of AKR7A2 protein CTD PMID:34915118 Akr7a5 Mouse 3-nitrobenzaldehyde affects reduction EXP 6480464 3-nitrobenzaldehyde affects the reduction of AKR7A5 protein and 3-nitrobenzaldehyde analog affects the reduction of AKR7A5 protein CTD PMID:12604212 Akr7a5 Mouse 3H-1,2-dithiole-3-thione increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in increased expression of AKR7A2 mRNA CTD PMID:19162173 Akr7a5 Mouse 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of AKR7A5 mRNA CTD PMID:18648102 Akr7a5 Mouse 4-amino-2,6-dinitrotoluene affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of AKR7A2 mRNA CTD PMID:21346803 Akr7a5 Mouse 4-hydroxynon-2-enal decreases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in decreased susceptibility to 4-hydroxy-2-nonenal CTD PMID:22001351 Akr7a5 Mouse 4-hydroxynon-2-enal affects response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein affects the susceptibility to 4-hydroxy-2-nonenal CTD PMID:30849339 Akr7a5 Mouse 4-hydroxynon-2-enal increases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal CTD PMID:22964423 Akr7a5 Mouse 4-hydroxynon-2-enal multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 7-hydroxycoumarin affects the reaction [AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal] and AKR7A2 protein affects the reaction [NFE2L2 protein affects the susceptibility to 4-hydroxy-2-nonenal] CTD PMID:22964423 and PMID:30849339 Akr7a5 Mouse 4-hydroxynon-2-enal increases expression ISO AKR7A2 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased expression of AKR7A2 mRNA and 4-hydroxy-2-nonenal results in increased expression of AKR7A2 protein CTD PMID:22964423 and PMID:30849339 Akr7a5 Mouse 4-nitrobenzaldehyde multiple interactions EXP 6480464 Ethacrynic Acid inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] more ... CTD PMID:12604212 Akr7a5 Mouse 4-nitrobenzaldehyde affects reduction EXP 6480464 4-nitrobenzaldehyde affects the reduction of AKR7A5 protein CTD PMID:12604212 Akr7a5 Mouse 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Omeprazole affects the expression of AKR7A2 mRNA CTD PMID:19483382 Akr7a5 Mouse 6-propyl-2-thiouracil affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Propylthiouracil affects the expression of AKR7A2 mRNA CTD PMID:19483382 Akr7a5 Mouse 7,12-dimethyltetraphene multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of and affects the activity of 9 more ... CTD PMID:21910479 Akr7a5 Mouse 9,10-phenanthroquinone increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of 9 and 10-phenanthrenequinone CTD PMID:10510318 Akr7a5 Mouse 9,10-phenanthroquinone multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of and affects the activity of 9 and 10-phenanthrenequinone CTD PMID:21910479 Akr7a5 Mouse 9,10-phenanthroquinone affects reduction EXP 6480464 9 and 10-phenanthrenequinone affects the reduction of AKR7A5 protein CTD PMID:12604212 Akr7a5 Mouse acetamide decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 acetamide results in decreased expression of AKR7A2 mRNA CTD PMID:31881176 Akr7a5 Mouse acrolein multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AKR7A2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of AKR7A2 mRNA CTD PMID:32699268 Akr7a5 Mouse acrylamide decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Acrylamide results in decreased expression of AKR7A2 mRNA CTD PMID:32763439 Akr7a5 Mouse aflatoxin B1 increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of AKR7A2 mRNA CTD PMID:22545673 Akr7a5 Mouse aflatoxin B1 decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Aflatoxin B1 results in decreased expression of AKR7A2 mRNA CTD PMID:23630614 Akr7a5 Mouse Aflatoxin B2 alpha decreases methylation ISO AKR7A2 (Homo sapiens) 6480464 aflatoxin B2 results in decreased methylation of AKR7A2 3' UTR CTD PMID:30157460 Akr7a5 Mouse alpha-pinene multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AKR7A2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of AKR7A2 mRNA CTD PMID:32699268 Akr7a5 Mouse amiodarone affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Amiodarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 Akr7a5 Mouse ammonium chloride affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of AKR7A2 mRNA CTD PMID:16483693 Akr7a5 Mouse antimycin A decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Antimycin A results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 Akr7a5 Mouse aristolochic acid A increases expression ISO AKR7A2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of AKR7A2 protein CTD PMID:33212167 Akr7a5 Mouse Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of AKR7A5 mRNA CTD PMID:23650126 Akr7a5 Mouse atorvastatin calcium increases expression ISO AKR7A2 (Homo sapiens) 6480464 Atorvastatin results in increased expression of AKR7A2 mRNA and Atorvastatin results in increased expression of AKR7A2 protein CTD PMID:38484826 Akr7a5 Mouse azoxystrobin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 azoxystrobin results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 Akr7a5 Mouse benzbromarone affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Benzbromarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 Akr7a5 Mouse benzo[a]pyrene-7,8-dione multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7 more ... CTD PMID:21910479 Akr7a5 Mouse beta-naphthoflavone increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 beta-Naphthoflavone results in increased expression of AKR7A2 mRNA and beta-Naphthoflavone results in increased expression of AKR7A2 protein CTD PMID:19389873 Akr7a5 Mouse bisphenol A multiple interactions ISO Akr7a2 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of AKR7A2 mRNA CTD PMID:26496021 Akr7a5 Mouse bisphenol A decreases methylation ISO AKR7A2 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of AKR7A2 gene CTD PMID:31601247 Akr7a5 Mouse bisphenol A multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of AKR7A2 gene CTD PMID:31601247 Akr7a5 Mouse bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of AKR7A5 mRNA CTD PMID:35598803 Akr7a5 Mouse bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of AKR7A5 mRNA CTD PMID:33221593 Akr7a5 Mouse bisphenol A affects expression ISO AKR7A2 (Homo sapiens) 6480464 bisphenol A affects the expression of AKR7A2 mRNA CTD PMID:30903817 Akr7a5 Mouse bisphenol A increases methylation ISO Akr7a2 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of AKR7A2 gene CTD PMID:28505145 Akr7a5 Mouse bisphenol A increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of AKR7A2 mRNA CTD PMID:30816183 Akr7a5 Mouse bisphenol A affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 bisphenol A affects the expression of AKR7A2 mRNA CTD PMID:25181051 Akr7a5 Mouse bisphenol AF increases expression ISO AKR7A2 (Homo sapiens) 6480464 bisphenol AF results in increased expression of AKR7A2 protein CTD PMID:34186270 Akr7a5 Mouse bisphenol F increases expression ISO AKR7A2 (Homo sapiens) 6480464 bisphenol F results in increased expression of AKR7A2 protein CTD PMID:34186270 Akr7a5 Mouse bortezomib multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in decreased expression of AKR7A2 mRNA CTD PMID:25522274 Akr7a5 Mouse Brodifacoum increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 bromfenacoum results in increased expression of AKR7A2 protein CTD PMID:28903499 Akr7a5 Mouse cadmium atom multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR7A2 mRNA CTD PMID:35301059 Akr7a5 Mouse cadmium dichloride multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR7A2 mRNA CTD PMID:35301059 Akr7a5 Mouse CGP 52608 multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to AKR7A2 gene] CTD PMID:28238834 Akr7a5 Mouse chenodeoxycholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 Akr7a5 Mouse chlordecone multiple interactions EXP 6480464 Chlordecone promotes the reaction [Biomarkers metabolite binds to AKR7A5 gene] CTD PMID:31084621 Akr7a5 Mouse cisplatin increases expression ISO AKR7A2 (Homo sapiens) 6480464 Cisplatin results in increased expression of AKR7A2 mRNA CTD PMID:27594783 Akr7a5 Mouse clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of AKR7A5 mRNA CTD PMID:17585979 Akr7a5 Mouse clofibrate increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Clofibrate results in increased expression of AKR7A2 protein CTD PMID:16470657 Akr7a5 Mouse clofibrate affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Clofibrate affects the expression of AKR7A2 mRNA CTD PMID:19483382 Akr7a5 Mouse cobalt dichloride decreases expression ISO AKR7A2 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of AKR7A2 mRNA CTD PMID:19376846 Akr7a5 Mouse copper(II) sulfate decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of AKR7A2 mRNA CTD PMID:19549813 Akr7a5 Mouse cyclosporin A decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of AKR7A2 mRNA CTD PMID:20106945 and PMID:25562108 Akr7a5 Mouse cyclosporin A multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 Akr7a5 Mouse deguelin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 deguelin results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 Akr7a5 Mouse deoxycholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 Akr7a5 Mouse Dibutyl phosphate affects expression ISO AKR7A2 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of AKR7A2 mRNA CTD PMID:37042841 Akr7a5 Mouse dibutyl phthalate decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in decreased expression of AKR7A2 mRNA CTD PMID:21266533 Akr7a5 Mouse dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of AKR7A5 mRNA CTD PMID:17361019 and PMID:21266533 Akr7a5 Mouse dimethylarsinic acid multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of AKR7A5 mRNA CTD PMID:34876320 Akr7a5 Mouse dioxygen multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in decreased abundance of Oxygen more ... CTD PMID:21910479 Akr7a5 Mouse doxorubicin increases metabolic processing ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 results in increased metabolism of Doxorubicin CTD PMID:20837989 Akr7a5 Mouse doxorubicin increases phosphorylation ISO AKR7A2 (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of AKR7A2 protein CTD PMID:30817976 Akr7a5 Mouse doxorubicin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of AKR7A2 mRNA CTD PMID:30817976 Akr7a5 Mouse endosulfan decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of AKR7A2 mRNA CTD PMID:29391264 Akr7a5 Mouse epoxiconazole increases expression EXP 6480464 epoxiconazole results in increased expression of AKR7A5 mRNA CTD PMID:35436446 Akr7a5 Mouse etacrynic acid multiple interactions EXP 6480464 Ethacrynic Acid inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] CTD PMID:12604212 Akr7a5 Mouse fenpyroximate decreases expression ISO AKR7A2 (Homo sapiens) 6480464 fenpyroximate results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 Akr7a5 Mouse folic acid multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of AKR7A5 mRNA] CTD PMID:22206623 Akr7a5 Mouse FR900359 increases phosphorylation ISO AKR7A2 (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of AKR7A2 protein CTD PMID:37730182 Akr7a5 Mouse fulvestrant multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of AKR7A2 gene CTD PMID:31601247 Akr7a5 Mouse furan affects binding ISO Akr7a2 (Rattus norvegicus) 6480464 furan binds to AKR7A2 protein CTD PMID:22240984 Akr7a5 Mouse furfural multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [pyrogallol 1 more ... CTD PMID:38598786 Akr7a5 Mouse gentamycin increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of AKR7A2 mRNA CTD PMID:33387578 Akr7a5 Mouse glafenine decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Glafenine results in decreased expression of AKR7A2 mRNA CTD PMID:24136188 Akr7a5 Mouse glutathione increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Glutathione deficiency results in increased expression of AKR7A2 mRNA CTD PMID:15345336 Akr7a5 Mouse glutathione multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein inhibits the reaction [Vitamin K 3 results in decreased abundance of Glutathione] CTD PMID:22001351 Akr7a5 Mouse glycochenodeoxycholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 Akr7a5 Mouse glycocholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 Akr7a5 Mouse glycodeoxycholic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A2 mRNA and [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:32152650 and PMID:33819548 Akr7a5 Mouse hexanal decreases response to substance EXP 6480464 AKR7A5 protein results in decreased susceptibility to n-hexanal CTD PMID:24590062 Akr7a5 Mouse hydrogen peroxide multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in increased chemical synthesis of Hydrogen Peroxide more ... CTD PMID:21910479 Akr7a5 Mouse hydrogen peroxide decreases response to substance EXP 6480464 AKR7A5 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:24590062 Akr7a5 Mouse hydrogen peroxide increases expression ISO AKR7A2 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of AKR7A2 protein CTD PMID:22964423 Akr7a5 Mouse hydrogen peroxide increases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 mutant form results in increased susceptibility to Hydrogen Peroxide CTD PMID:22964423 Akr7a5 Mouse hypochlorous acid decreases expression EXP 6480464 Hypochlorous Acid results in decreased expression of AKR7A5 mRNA CTD PMID:19376150 Akr7a5 Mouse indole-3-methanol increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 indole-3-carbinol results in increased expression of AKR7A5 CTD PMID:9806166 Akr7a5 Mouse indometacin multiple interactions EXP 6480464 Indomethacin inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] CTD PMID:12604212 Akr7a5 Mouse inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AKR7A5 mRNA CTD PMID:36331819 Akr7a5 Mouse isatin affects reduction EXP 6480464 Isatin affects the reduction of AKR7A5 protein CTD PMID:12604212 Akr7a5 Mouse isatin increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of Isatin CTD PMID:10510318 Akr7a5 Mouse ivermectin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of AKR7A2 protein CTD PMID:32959892 Akr7a5 Mouse L-ethionine affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Ethionine affects the expression of AKR7A2 mRNA CTD PMID:19483382 Akr7a5 Mouse leflunomide increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 leflunomide results in increased expression of AKR7A2 mRNA CTD PMID:24136188 Akr7a5 Mouse menadione multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein inhibits the reaction [Vitamin K 3 results in decreased abundance of Glutathione] and AKR7A2 protein inhibits the reaction [Vitamin K 3 results in increased abundance of Reactive Oxygen Species] CTD PMID:22001351 Akr7a5 Mouse menadione increases metabolic processing EXP 6480464 AKR7A5 protein results in increased metabolism of Vitamin K 3 CTD PMID:24590062 Akr7a5 Mouse menadione decreases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in decreased susceptibility to Vitamin K 3 CTD PMID:22001351 Akr7a5 Mouse methamphetamine decreases methylation EXP 6480464 Methamphetamine results in decreased methylation of AKR7A5 promoter CTD PMID:26307267 Akr7a5 Mouse methylarsonic acid multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of AKR7A5 mRNA CTD PMID:34876320 Akr7a5 Mouse methylglyoxal decreases response to substance EXP 6480464 AKR7A5 protein results in decreased susceptibility to Pyruvaldehyde CTD PMID:24590062 Akr7a5 Mouse methylglyoxal increases expression ISO AKR7A2 (Homo sapiens) 6480464 Pyruvaldehyde results in increased expression of AKR7A2 mRNA and Pyruvaldehyde results in increased expression of AKR7A2 protein CTD PMID:25451587 Akr7a5 Mouse methylglyoxal decreases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in decreased susceptibility to Pyruvaldehyde CTD PMID:22001351 and PMID:25451587 Akr7a5 Mouse Muconic dialdehyde decreases response to substance EXP 6480464 AKR7A5 protein results in decreased susceptibility to muconaldehyde analog CTD PMID:24590062 Akr7a5 Mouse Muconic dialdehyde decreases response to substance ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in decreased susceptibility to muconaldehyde CTD PMID:22001351 Akr7a5 Mouse N-nitrosomorpholine decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 N-nitrosomorpholine results in decreased expression of AKR7A2 protein CTD PMID:19716841 Akr7a5 Mouse NADP zwitterion multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in decreased abundance of Oxygen more ... CTD PMID:21910479 Akr7a5 Mouse NADP(+) multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in decreased abundance of Oxygen more ... CTD PMID:21910479 Akr7a5 Mouse naphthalenes multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of and affects the activity of Naphthalenes CTD PMID:21910479 Akr7a5 Mouse naringin multiple interactions EXP 6480464 naringin inhibits the reaction [Acetaminophen results in decreased expression of AKR7A5 protein] CTD PMID:35166444 Akr7a5 Mouse nefazodone increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 nefazodone results in increased expression of AKR7A2 mRNA CTD PMID:24136188 Akr7a5 Mouse nimesulide increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 nimesulide results in increased expression of AKR7A2 mRNA CTD PMID:24136188 Akr7a5 Mouse non-2-enal decreases response to substance EXP 6480464 AKR7A5 protein results in decreased susceptibility to 2-nonenal CTD PMID:24590062 Akr7a5 Mouse omeprazole affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Omeprazole affects the expression of AKR7A2 mRNA CTD PMID:19483382 Akr7a5 Mouse oxaliplatin multiple interactions ISO Akr7a2 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of AKR7A2 mRNA CTD PMID:25729387 Akr7a5 Mouse oxaliplatin decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 oxaliplatin results in decreased expression of AKR7A2 mRNA CTD PMID:25729387 Akr7a5 Mouse ozone multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AKR7A2 mRNA more ... CTD PMID:32699268 and PMID:35430440 Akr7a5 Mouse ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of AKR7A5 mRNA CTD PMID:34911549 Akr7a5 Mouse paracetamol increases expression ISO AKR7A2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of AKR7A2 mRNA CTD PMID:25704631 Akr7a5 Mouse paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of AKR7A5 protein CTD PMID:35166444 Akr7a5 Mouse paracetamol multiple interactions EXP 6480464 naringin inhibits the reaction [Acetaminophen results in decreased expression of AKR7A5 protein] CTD PMID:35166444 Akr7a5 Mouse paracetamol increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of AKR7A2 mRNA CTD PMID:33387578 Akr7a5 Mouse perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of AKR7A5 mRNA CTD PMID:36331819 Akr7a5 Mouse perfluorooctanoic acid increases expression ISO AKR7A2 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of AKR7A2 protein CTD PMID:26879310 Akr7a5 Mouse phenobarbital affects expression ISO AKR7A2 (Homo sapiens) 6480464 Phenobarbital affects the expression of AKR7A2 mRNA CTD PMID:19159669 Akr7a5 Mouse phlorizin increases expression EXP 6480464 Phlorhizin results in increased expression of AKR7A2 mRNA CTD PMID:22538082 Akr7a5 Mouse picoxystrobin decreases expression ISO AKR7A2 (Homo sapiens) 6480464 picoxystrobin results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 Akr7a5 Mouse pirinixic acid multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of AKR7A2 mRNA CTD PMID:19710929 Akr7a5 Mouse pirinixic acid affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 pirinixic acid affects the expression of AKR7A2 mRNA CTD PMID:19483382 Akr7a5 Mouse piroxicam decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Piroxicam results in decreased expression of AKR7A2 mRNA CTD PMID:21858171 Akr7a5 Mouse Propiverine affects binding ISO Akr7a2 (Rattus norvegicus) 6480464 propiverine binds to AKR7A2 protein CTD PMID:29273565 Akr7a5 Mouse pyrimidifen decreases expression ISO AKR7A2 (Homo sapiens) 6480464 pyrimidifen results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 Akr7a5 Mouse quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] CTD PMID:12604212 Akr7a5 Mouse raloxifene affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Raloxifene Hydrochloride affects the expression of AKR7A2 mRNA CTD PMID:16079270 Akr7a5 Mouse reactive oxygen species multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein inhibits the reaction [Vitamin K 3 results in increased abundance of Reactive Oxygen Species] CTD PMID:22001351 Akr7a5 Mouse rotenone decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Rotenone results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 Akr7a5 Mouse sodium arsenate multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of AKR7A5 mRNA CTD PMID:34876320 Akr7a5 Mouse sodium arsenite increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of AKR7A2 protein CTD PMID:29459688 Akr7a5 Mouse sodium arsenite multiple interactions EXP 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of AKR7A5 mRNA CTD PMID:34876320 Akr7a5 Mouse sodium arsenite decreases expression ISO AKR7A2 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of AKR7A2 mRNA CTD PMID:38568856 Akr7a5 Mouse sodium chloride multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of AKR7A2 protein CTD PMID:38598786 Akr7a5 Mouse sodium fluoride decreases expression EXP 6480464 Sodium Fluoride results in decreased expression of AKR7A2 protein CTD PMID:28918527 Akr7a5 Mouse Soman decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Soman results in decreased expression of AKR7A2 mRNA CTD PMID:19281266 Akr7a5 Mouse succinic semialdehyde increases reduction ISO AKR7A2 (Homo sapiens) 6480464 AKR7A2 protein results in increased reduction of succinic semialdehyde CTD PMID:10510318 Akr7a5 Mouse succinic semialdehyde affects reduction EXP 6480464 succinic semialdehyde affects the reduction of AKR7A5 protein CTD PMID:12604212 Akr7a5 Mouse superoxide multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [[AKR7A2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone] which results in increased chemical synthesis of Superoxides more ... CTD PMID:21910479 Akr7a5 Mouse tartrazine multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in decreased expression of AKR7A2 mRNA CTD PMID:33819548 Akr7a5 Mouse tebufenpyrad decreases expression ISO AKR7A2 (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of AKR7A2 mRNA CTD PMID:33512557 Akr7a5 Mouse tetrachloromethane decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of AKR7A2 mRNA CTD PMID:31150632 Akr7a5 Mouse tetrachloromethane multiple interactions ISO Akr7a2 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of AKR7A2 mRNA] CTD PMID:31150632 Akr7a5 Mouse thioacetamide affects expression ISO Akr7a2 (Rattus norvegicus) 6480464 Thioacetamide affects the expression of AKR7A2 mRNA CTD PMID:19483382 Akr7a5 Mouse thioacetamide decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of AKR7A2 mRNA CTD PMID:34492290 Akr7a5 Mouse thiram decreases expression ISO AKR7A2 (Homo sapiens) 6480464 Thiram results in decreased expression of AKR7A2 mRNA CTD PMID:38568856 Akr7a5 Mouse topotecan multiple interactions ISO Akr7a2 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of AKR7A2 mRNA CTD PMID:25729387 Akr7a5 Mouse topotecan decreases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Topotecan results in decreased expression of AKR7A2 mRNA CTD PMID:25729387 Akr7a5 Mouse trichloroethene increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of AKR7A2 mRNA CTD PMID:33387578 Akr7a5 Mouse triphenyl phosphate increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 triphenyl phosphate results in increased expression of AKR7A2 mRNA CTD PMID:30589522 Akr7a5 Mouse Triptolide increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 triptolide results in increased expression of AKR7A2 protein CTD PMID:32519852 Akr7a5 Mouse umbelliferone increases expression ISO AKR7A2 (Homo sapiens) 6480464 7-hydroxycoumarin results in increased expression of AKR7A2 mRNA and 7-hydroxycoumarin results in increased expression of AKR7A2 protein CTD PMID:22964423 more ... Akr7a5 Mouse umbelliferone multiple interactions ISO AKR7A2 (Homo sapiens) 6480464 7-hydroxycoumarin affects the reaction [AKR7A2 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal] CTD PMID:22964423 Akr7a5 Mouse valproic acid multiple interactions EXP 6480464 Valproic Acid inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] CTD PMID:12604212 Akr7a5 Mouse vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of AKR7A5 mRNA CTD PMID:18930951 Akr7a5 Mouse vinclozolin increases expression ISO Akr7a2 (Rattus norvegicus) 6480464 vinclozolin results in increased expression of AKR7A2 mRNA CTD PMID:22570695