Zg16 (zymogen granule protein 16) - Rat Genome Database

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Gene: Zg16 (zymogen granule protein 16) Mus musculus
Analyze
Symbol: Zg16
Name: zymogen granule protein 16
RGD ID: 732667
MGI Page MGI
Description: Enables peptidoglycan binding activity. Acts upstream of or within defense response to Gram-positive bacterium and suppression of symbiont entry into host. Located in mucus layer. Orthologous to human ZG16 (zymogen granule protein 16).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1810010M01Rik; AI593689; secretory lectin ZG16; ZG16p; zymogen granule membrane protein 16
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,649,328 - 126,651,847 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,649,328 - 126,686,500 (-)EnsemblGRCm39 Ensembl
GRCm387127,050,156 - 127,052,675 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,050,156 - 127,087,328 (-)EnsemblGRCm38mm10GRCm38
MGSCv377134,193,670 - 134,195,491 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367126,841,304 - 126,843,125 (-)NCBIMGSCv36mm8
Celera7126,898,388 - 126,900,209 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:15097871   PMID:15489334   PMID:16141072   PMID:16141073   PMID:21267068   PMID:21873635   PMID:27827809   PMID:27849619  
PMID:37829188   PMID:38355793   PMID:39191121  


Genomics

Comparative Map Data
Zg16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,649,328 - 126,651,847 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,649,328 - 126,686,500 (-)EnsemblGRCm39 Ensembl
GRCm387127,050,156 - 127,052,675 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,050,156 - 127,087,328 (-)EnsemblGRCm38mm10GRCm38
MGSCv377134,193,670 - 134,195,491 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367126,841,304 - 126,843,125 (-)NCBIMGSCv36mm8
Celera7126,898,388 - 126,900,209 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.3NCBI
ZG16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381629,778,256 - 29,782,973 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1629,778,256 - 29,782,973 (+)EnsemblGRCh38hg38GRCh38
GRCh371629,789,577 - 29,794,294 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361629,697,110 - 29,700,597 (+)NCBINCBI36Build 36hg18NCBI36
Celera1673,004,439 - 73,006,715 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1627,450,374 - 27,453,779 (+)NCBIHuRef
CHM1_11631,005,493 - 31,008,898 (+)NCBICHM1_1
T2T-CHM13v2.01630,060,382 - 30,065,096 (+)NCBIT2T-CHM13v2.0
Zg16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,088,248 - 191,090,605 (-)NCBIGRCr8
mRatBN7.21181,657,722 - 181,660,079 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,657,722 - 181,660,079 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,009,170 - 190,011,526 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,195,254 - 197,197,610 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,862,672 - 189,865,028 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,483,800 - 198,486,157 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,483,805 - 198,486,157 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,474,980 - 205,477,337 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,300,807 - 186,303,164 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,450,692 - 186,453,049 (-)NCBI
Celera1179,313,389 - 179,315,746 (-)NCBICelera
Cytogenetic Map1q37NCBI
Zg16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,181,555 - 7,184,589 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,183,096 - 7,201,750 (-)NCBIChiLan1.0ChiLan1.0
ZG16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21830,527,844 - 30,532,555 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11635,693,332 - 35,698,044 (-)NCBINHGRI_mPanPan1
PanPan1.11630,149,307 - 30,151,579 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,149,307 - 30,151,579 (+)Ensemblpanpan1.1panPan2
ZG16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,840,430 - 17,842,008 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,839,553 - 17,842,006 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,417,571 - 19,419,157 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,974,338 - 17,975,924 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,973,464 - 17,975,916 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,773,923 - 17,775,509 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,689,607 - 17,691,193 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,004,901 - 18,006,487 (+)NCBIUU_Cfam_GSD_1.0
Zg16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344124,601,301 - 124,603,692 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650112,699,200 - 12,700,979 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650112,699,197 - 12,700,697 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZG16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1318,018,866 - 18,019,501 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ZG16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,873,363 - 26,875,944 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,872,263 - 26,874,595 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660682,652,931 - 2,654,068 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Zg16
88 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:189
Count of miRNA genes:183
Interacting mature miRNAs:189
Transcripts:ENSMUST00000051122
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7101693381135693530Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
11059561Lmr21a_mleishmaniasis resistance 21a (mouse)7117750722127967336Mouse
38501066Tip2_mtuberculosis immunophenotype 2, spleen CFU (mouse)7124299223126899172Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7110967235144967336Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111166122144995196Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
4141945Il4ppq_mIL-4 producing potential QTL (mouse)Not determined7124513662128819324Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7100750722134750843Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112552248144995196Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7100993261134993342Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined799837716133837716Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7116634089144995196Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102485219136485380Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7112922733144995196Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111166122144995196Mouse
38501072Stsl7_mSalmonella typhimurium susceptibility locus 7 (mouse)7115699235128501724Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7118693381144398314Mouse
1301903Tlsm1_mthymic lymphoma susceptible 1 (mouse)Not determined7122250663135170901Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7110967235144967336Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119132573144995196Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7101693381135693530Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7101693381135693530Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793391848127392041Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105250663139250811Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7109707335143707335Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111166122144995196Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7109707335143707335Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7109707335143707335Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798164922132165010Mouse
1357613Bsbob2_mBSB obesity 2 (mouse)Not determined7122250663128819324Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105350008139350008Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798394974132394974Mouse
15092059Wogrme1_mweek one growth rate, maternal effect 1 (mouse)7117199227134101729Mouse

Markers in Region
AI593689  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387127,050,214 - 127,050,298UniSTSGRCm38
MGSCv377134,193,728 - 134,193,812UniSTSGRCm37
Celera7126,898,446 - 126,898,530UniSTS
Cytogenetic Map7F4UniSTS
Whitehead/MRC_RH71293.21UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000051122   ⟹   ENSMUSP00000056916
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7126,649,328 - 126,651,149 (-)Ensembl
GRCm38.p6 Ensembl7127,050,156 - 127,051,977 (-)Ensembl
Ensembl Acc Id: ENSMUST00000205424   ⟹   ENSMUSP00000145876
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7126,649,328 - 126,651,847 (-)Ensembl
GRCm38.p6 Ensembl7127,050,156 - 127,052,675 (-)Ensembl
Ensembl Acc Id: ENSMUST00000205559   ⟹   ENSMUSP00000145957
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7126,649,648 - 126,686,500 (-)Ensembl
GRCm38.p6 Ensembl7127,050,476 - 127,087,328 (-)Ensembl
Ensembl Acc Id: ENSMUST00000205623
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7126,662,907 - 126,686,458 (-)Ensembl
GRCm38.p6 Ensembl7127,063,735 - 127,087,286 (-)Ensembl
RefSeq Acc Id: NM_026918   ⟹   NP_081194
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397126,649,328 - 126,651,847 (-)NCBI
GRCm387127,050,156 - 127,052,675 (-)NCBI
MGSCv377134,193,670 - 134,195,491 (-)RGD
Celera7126,898,388 - 126,900,209 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_081194 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH31800 (Get FASTA)   NCBI Sequence Viewer  
  BAB25031 (Get FASTA)   NCBI Sequence Viewer  
  EDL17498 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000056916.6
  ENSMUSP00000145876
  ENSMUSP00000145876.2
  ENSMUSP00000145957.2
GenBank Protein Q8K0C5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_081194   ⟸   NM_026918
- Peptide Label: precursor
- UniProtKB: Q8K0C5 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000056916   ⟸   ENSMUST00000051122
Ensembl Acc Id: ENSMUSP00000145876   ⟸   ENSMUST00000205424
Ensembl Acc Id: ENSMUSP00000145957   ⟸   ENSMUST00000205559
Protein Domains
Jacalin-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K0C5-F1-model_v2 AlphaFold Q8K0C5 1-167 view protein structure

Promoters
RGD ID:8665633
Promoter ID:EPDNEW_M10848
Type:multiple initiation site
Name:Zg16_1
Description:Mus musculus zymogen granule protein 16 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387127,052,005 - 127,052,065EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916286 AgrOrtholog
Ensembl Genes ENSMUSG00000049350 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000051122.7 UniProtKB/Swiss-Prot
  ENSMUST00000205424 ENTREZGENE
  ENSMUST00000205424.2 UniProtKB/Swiss-Prot
  ENSMUST00000205559.2 UniProtKB/TrEMBL
Gene3D-CATH 2.100.10.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Jacalin-like_lectin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Jacalin-like_lectin_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PolyBind_ProtTraffic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69036 UniProtKB/Swiss-Prot
MGD MGI:1916286 ENTREZGENE
NCBI Gene 69036 ENTREZGENE
PANTHER OS11G0524900 PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR33589:SF4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Jacalin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Zg16 PhenoGen
PROSITE JACALIN_LECTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Jacalin UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51101 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RPF0_MOUSE UniProtKB/TrEMBL
  Q8K0C5 ENTREZGENE
  Q9CVM6_MOUSE UniProtKB/TrEMBL
  ZG16_MOUSE UniProtKB/Swiss-Prot