Epcam (epithelial cell adhesion molecule) - Rat Genome Database

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Gene: Epcam (epithelial cell adhesion molecule) Mus musculus
Analyze
Symbol: Epcam
Name: epithelial cell adhesion molecule
RGD ID: 732608
MGI Page MGI
Description: Predicted to enable cadherin binding activity involved in cell-cell adhesion. Involved in ureteric bud development. Located in cell surface. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study congenital diarrhea 5 with tufting enteropathy. Human ortholog(s) of this gene implicated in congenital diarrhea 5 with tufting enteropathy and hereditary nonpolyposis colorectal cancer type 8. Orthologous to human EPCAM (epithelial cell adhesion molecule).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CD326; EGP; EGP-; EGP-2; Egp31; Egp314; Ep-C; Ep-CAM; EpC; EpCA; EpCAM1; epithelial glycoprotein 314; GA733-; GA733-2; gp4; gp40; Ly7; Ly74; lymphocyte antigen 74; mEGP314; panepithelial glycoprotein 314; protein 289A; Tacsd1; Tacst; Tacstd1; TR; Trop-1 protein; TROP1; tumor-associated calcium signal transducer 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391787,943,407 - 87,958,555 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1787,943,407 - 87,958,557 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381787,635,979 - 87,651,127 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1787,635,979 - 87,651,129 (+)Ensemblmm10GRCm38
MGSCv371788,035,319 - 88,050,467 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361787,545,034 - 87,559,453 (+)NCBIMGSCv36mm8
Celera1792,042,942 - 92,058,080 (+)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1757.87NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinin  (ISO)
(+)-schisandrin B  (ISO)
(20S)-ginsenoside Rg3  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
1-nitropropane  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-diaminotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-diaminotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-nitro-p-phenylenediamine  (ISO)
2-nitropropane  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (EXP)
3-methylfuran  (ISO)
3-Nitrobenzanthrone  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-acetylaminofluorene  (ISO)
4-hydroxyphenyl retinamide  (EXP)
4-nitro-1,2-phenylenediamine  (ISO)
4-nitroquinoline N-oxide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (EXP,ISO)
alpha-hexachlorocyclohexane  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
ampicillin  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butan-1-ol  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carboplatin  (ISO)
casticin  (ISO)
chlordecone  (EXP)
chlorpyrifos  (EXP)
choline  (EXP)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (EXP)
crizotinib  (ISO)
cumene  (EXP)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
DDE  (ISO)
diarsenic trioxide  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
eugenol  (EXP,ISO)
flavonol  (ISO)
flutamide  (ISO)
folic acid  (EXP)
furan  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glucose  (EXP)
glycidol  (ISO)
GW 3965  (EXP)
indole-3-methanol  (ISO)
inulin  (EXP)
iron dichloride  (ISO)
L-ethionine  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
lidocaine  (ISO)
mercury dibromide  (ISO)
methamphetamine  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
metronidazole  (ISO)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
Monobutylphthalate  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (ISO)
neomycin  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
omeprazole  (ISO)
p-chloromercuribenzoic acid  (ISO)
p-toluidine  (ISO)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
raloxifene  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
SCH 23390  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
streptozocin  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (ISO)
vinorelbine  (ISO)
vorinostat  (ISO)
XMU-MP-1  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Cancer stem cell markers correlate with early recurrence and survival in hepatocellular carcinoma. Guo Z, etal., World J Gastroenterol. 2014 Feb 28;20(8):2098-106. doi: 10.3748/wjg.v20.i8.2098.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. EGP-314 is expressed differentially in three brain zones at an early time in an experimentally induced ischemia rat model. Ortiz-Plata A, etal., Brain Res Mol Brain Res. 2005 Jun 13;137(1-2):55-62. Epub 2005 Apr 7.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. EpCAM-associated claudin-7 supports lymphatic spread and drug resistance in rat pancreatic cancer. Thuma F and Zoller M, Int J Cancer. 2013 Aug 15;133(4):855-66. doi: 10.1002/ijc.28085. Epub 2013 Mar 9.
Additional References at PubMed
PMID:1729376   PMID:2326198   PMID:8566052   PMID:8617310   PMID:10349636   PMID:10512203   PMID:10585755   PMID:10615264   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11358833  
PMID:11812828   PMID:12477932   PMID:12520002   PMID:14610273   PMID:14681479   PMID:15793245   PMID:15840001   PMID:16141072   PMID:16141073   PMID:16545622   PMID:16602821   PMID:17328885  
PMID:17599412   PMID:17694573   PMID:17882221   PMID:17981779   PMID:18025791   PMID:18554416   PMID:18799149   PMID:18799693   PMID:19002182   PMID:19015306   PMID:19097184   PMID:19369401  
PMID:19429791   PMID:19527784   PMID:20046825   PMID:20404099   PMID:21267068   PMID:21377456   PMID:21469133   PMID:21535318   PMID:21614016   PMID:21858196   PMID:21873635   PMID:22194864  
PMID:22266179   PMID:22411813   PMID:22425250   PMID:22451941   PMID:22497843   PMID:22509524   PMID:22786774   PMID:22819673   PMID:22865702   PMID:23209569   PMID:23322300   PMID:24009667  
PMID:24069263   PMID:24337010   PMID:24482234   PMID:24636260   PMID:24780627   PMID:24850856   PMID:25290738   PMID:25358791   PMID:25482158   PMID:25733567   PMID:25770130   PMID:25919081  
PMID:26222436   PMID:26265072   PMID:26365194   PMID:26764350   PMID:26989172   PMID:27019112   PMID:27106675   PMID:27238716   PMID:27531557   PMID:27721471   PMID:27770432   PMID:27861793  
PMID:27974211   PMID:28077488   PMID:28094766   PMID:28109119   PMID:28157205   PMID:28380258   PMID:28407375   PMID:28431248   PMID:28457793   PMID:28576768   PMID:28698625   PMID:28864008  
PMID:28935707   PMID:28951464   PMID:29037931   PMID:29249464   PMID:29361536   PMID:29540203   PMID:29615468   PMID:29617460   PMID:29899403   PMID:29958886   PMID:30089273   PMID:30244870  
PMID:30254276   PMID:30566624   PMID:30598504   PMID:30988300   PMID:31160421   PMID:31171776   PMID:31424120   PMID:31433211   PMID:31524221   PMID:31772170   PMID:31953387   PMID:31972158  
PMID:32005677   PMID:32350257   PMID:32597756   PMID:32781650   PMID:32878924   PMID:33188776   PMID:33230114   PMID:33305192   PMID:33416101   PMID:33470182   PMID:33525555   PMID:33707780  
PMID:33882290   PMID:33914869   PMID:33993983   PMID:34042944   PMID:34233187   PMID:34321999   PMID:34348153   PMID:34524864   PMID:34927678   PMID:34963058   PMID:35075189   PMID:35077450  
PMID:35132078   PMID:35224622   PMID:35266581   PMID:35320729   PMID:35493520   PMID:35730316   PMID:35749158   PMID:36100434   PMID:36283963   PMID:36316325   PMID:36458554   PMID:36516755  
PMID:36543770   PMID:36656901   PMID:37096042   PMID:37188818   PMID:37318953   PMID:37367826   PMID:37539662   PMID:37559721   PMID:37573008   PMID:37610090   PMID:37720106   PMID:38159590  
PMID:38265933   PMID:38441552   PMID:38905124   PMID:38971196   PMID:39040069   PMID:39092607   PMID:39224519   PMID:39392189   PMID:39699962   PMID:39745200   PMID:39824184   PMID:39955269  
PMID:40521668  


Genomics

Comparative Map Data
Epcam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391787,943,407 - 87,958,555 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1787,943,407 - 87,958,557 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381787,635,979 - 87,651,127 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1787,635,979 - 87,651,129 (+)Ensemblmm10GRCm38
MGSCv371788,035,319 - 88,050,467 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361787,545,034 - 87,559,453 (+)NCBIMGSCv36mm8
Celera1792,042,942 - 92,058,080 (+)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1757.87NCBI
EPCAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38247,369,311 - 47,387,020 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl247,345,158 - 47,387,601 (+)Ensemblhg38GRCh38
GRCh37247,596,450 - 47,614,159 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36247,449,971 - 47,467,661 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34247,508,117 - 47,525,808NCBI
Celera247,435,038 - 47,452,920 (+)NCBICelera
Cytogenetic Map2p21NCBI
HuRef247,332,819 - 47,350,813 (+)NCBIHuRef
CHM1_1247,526,380 - 47,544,227 (+)NCBICHM1_1
T2T-CHM13v2.0247,374,345 - 47,392,054 (+)NCBIT2T-CHM13v2.0
Epcam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8612,633,715 - 12,649,678 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl612,631,611 - 12,649,702 (-)EnsemblGRCr8
mRatBN7.266,880,142 - 6,896,103 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl66,878,237 - 6,896,127 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx67,162,229 - 7,178,185 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.067,471,633 - 7,487,591 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.066,998,763 - 7,014,715 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0611,282,194 - 11,308,870 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl611,281,964 - 11,298,216 (-)Ensemblrn6Rnor6.0
Rnor_5.0621,264,116 - 21,280,078 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4611,176,664 - 11,192,628 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera66,637,498 - 6,653,429 (-)NCBICelera
RGSC_v3.1611,176,663 - 11,192,627 (+)NCBI
Cytogenetic Map6q12NCBI
Epcam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544114,155,082 - 14,169,161 (+)Ensembl
ChiLan1.0NW_00495544114,155,084 - 14,167,584 (+)NCBIChiLan1.0ChiLan1.0
EPCAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21278,997,263 - 79,015,018 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A79,001,229 - 79,018,984 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A47,490,748 - 47,508,418 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A48,414,791 - 48,432,038 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A48,413,520 - 48,432,038 (+)EnsemblpanPan2panpan1.1
EPCAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11049,446,165 - 49,498,690 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1049,485,746 - 49,498,475 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1049,340,952 - 49,353,876 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01050,358,759 - 50,372,148 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1050,357,906 - 50,373,405 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11050,066,503 - 50,079,814 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01050,354,644 - 50,367,879 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01050,540,181 - 50,553,474 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Epcam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629233,590,900 - 33,604,003 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365085,019,918 - 5,032,414 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365085,019,513 - 5,032,610 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPCAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl393,168,852 - 93,185,653 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1393,169,800 - 93,185,221 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2399,312,713 - 99,328,225 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPCAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11459,815,128 - 59,832,360 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1459,815,064 - 59,832,229 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604552,016,345 - 52,034,127 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Epcam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473828,754,602 - 28,770,758 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473828,755,039 - 28,770,160 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Epcam
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v175,324,704 - 5,341,046 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Epcam
522 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:144
Count of miRNA genes:134
Interacting mature miRNAs:139
Transcripts:ENSMUST00000053577
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301107Scc4_mcolon tumor susceptibility 4 (mouse)Not determined176230101095294699Mouse
4141758Pstc5_mperiosteal circumference 5 (mouse)Not determined175710765191107803Mouse
11039498Ltpr7b_mLeishmania tropica response 7b (mouse)177070119895294699Mouse
11039499Ltpr7a_mLeishmania tropica response 7a (mouse)177070119895294699Mouse
11039500Ltpr7c_mLeishmania tropica response 7c (mouse)177070119895294699Mouse
1357552Aaj4_manxiety in A/J 4 (mouse)Not determined177458908990395270Mouse
11528551Sluc32_msusceptibility to lung cancer 32 (mouse)176230101095294699Mouse
4141011Bmd26_mbone mineral density 26 (mouse)Not determined175710765191107803Mouse
1300735Pgia20_mproteoglycan induced arthritis 20 (mouse)Not determined175710765191107803Mouse
12910536Nrq8a_mnoise-induced hearing loss resistant QTL 8a (mouse)175710765191107803Mouse
1357528Nhdlq3_mnon-HDL QTL 3 (mouse)Not determined177339513295294699Mouse
14697708Stsl5_mSalmonella typhimurium susceptibility locus 5 (mouse)178080742991407428Mouse
12910537Nrq8_mnoise-induced hearing loss resistant QTL 8 (mouse)175710765191107803Mouse
4141040Hmtb9_mhemostasis and thrombosis rebleeding time 9 (mouse)Not determined5758908991589197Mouse
4142256Nilac12_mnicotine induced locomotor activity 12 (mouse)Not determined176894131995294699Mouse
4142414Pregq4_mpregnancy QTL 4 (mouse)Not determined175753444793507179Mouse
1302017Aliq3_macute lung injury QTL 3 (mouse)Not determined176388554895294699Mouse
11039514Ltpr7_mLeishmania tropica response 7 (mouse)177070119895294699Mouse
1357447Heal13_mwound healing/regeneration 13 (mouse)Not determined175710765191107803Mouse
1301728Ffal1_mfree fatty acid level 1 (mouse)Not determined176521493895294699Mouse
4141195Nilac11_mnicotine induced locomotor activity 11 (mouse)Not determined177339513295294699Mouse
14928308Manh82_mmandible shape 82 (mouse)176631524395294699Mouse
1357646Axtq3_manxiety QTL 3 (mouse)Not determined177458908990395270Mouse
4141697Hbnr3_mHeligmosomoides bakeri nematode resistance 3 (mouse)Not determined7410765193507179Mouse

Markers in Region
AW214593  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381787,650,693 - 87,650,777UniSTSGRCm38
MGSCv371788,050,033 - 88,050,117UniSTSGRCm37
Celera1792,057,648 - 92,057,732UniSTS
Cytogenetic Map17E4UniSTS
Whitehead/MRC_RH171084.27UniSTS
Tacstd1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17E4UniSTS
cM Map17 UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000053577   ⟹   ENSMUSP00000061935
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,943,407 - 87,958,534 (+)Ensembl
GRCm38.p6 Ensembl1787,635,979 - 87,651,106 (+)Ensembl
Ensembl Acc Id: ENSMUST00000234009   ⟹   ENSMUSP00000157099
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,943,423 - 87,947,864 (+)Ensembl
GRCm38.p6 Ensembl1787,635,995 - 87,640,436 (+)Ensembl
Ensembl Acc Id: ENSMUST00000234354
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,943,445 - 87,948,890 (+)Ensembl
GRCm38.p6 Ensembl1787,636,017 - 87,641,462 (+)Ensembl
Ensembl Acc Id: ENSMUST00000234623   ⟹   ENSMUSP00000157040
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,944,110 - 87,958,557 (+)Ensembl
GRCm38.p6 Ensembl1787,636,682 - 87,651,129 (+)Ensembl
Ensembl Acc Id: ENSMUST00000235125   ⟹   ENSMUSP00000157220
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1787,943,407 - 87,947,392 (+)Ensembl
GRCm38.p6 Ensembl1787,635,979 - 87,639,964 (+)Ensembl
RefSeq Acc Id: NM_008532   ⟹   NP_032558
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391787,943,407 - 87,958,555 (+)NCBI
GRCm381787,635,979 - 87,651,127 (+)ENTREZGENE
MGSCv371788,035,319 - 88,050,467 (+)RGD
Celera1792,042,942 - 92,058,080 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032558   ⟸   NM_008532
- Peptide Label: precursor
- UniProtKB: Q61512 (UniProtKB/Swiss-Prot),   Q99JW5 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000061935   ⟸   ENSMUST00000053577
Ensembl Acc Id: ENSMUSP00000157220   ⟸   ENSMUST00000235125
Ensembl Acc Id: ENSMUSP00000157040   ⟸   ENSMUST00000234623
Ensembl Acc Id: ENSMUSP00000157099   ⟸   ENSMUST00000234009
Protein Domains
Epithelial cell adhesion molecule N-terminal   Thyroglobulin type-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99JW5-F1-model_v2 AlphaFold Q99JW5 1-315 view protein structure

Promoters
RGD ID:13676956
Promoter ID:EPDNEW_M22627
Type:multiple initiation site
Name:Epcam_2
Description:Mus musculus epithelial cell adhesion molecule , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22628  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381787,635,981 - 87,636,041EPDNEW
RGD ID:13676958
Promoter ID:EPDNEW_M22628
Type:initiation region
Name:Epcam_1
Description:Mus musculus epithelial cell adhesion molecule , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M22627  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381787,636,731 - 87,636,791EPDNEW
RGD ID:6828080
Promoter ID:MM_KWN:24405
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Kidney,   Lung
Transcripts:ENSMUST00000053577
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361788,035,601 - 88,036,287 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:106653 AgrOrtholog
Ensembl Genes ENSMUSG00000045394 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000053577 ENTREZGENE
  ENSMUST00000053577.9 UniProtKB/Swiss-Prot
  ENSMUST00000234623.2 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.800.10 UniProtKB/Swiss-Prot
InterPro EPCAM-Trop-2_C UniProtKB/Swiss-Prot
  EPCAM/Trop-2 UniProtKB/Swiss-Prot
  EpCAM_N UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
  Thyroglobulin_1_sf UniProtKB/Swiss-Prot
KEGG Report mmu:17075 UniProtKB/Swiss-Prot
MGD MGI:106653 ENTREZGENE
NCBI Gene 17075 ENTREZGENE
PANTHER EPITHELIAL CELL ADHESION MOLECULE UniProtKB/Swiss-Prot
  PTHR14168 UniProtKB/Swiss-Prot
Pfam EPCAM-Trop-2_C UniProtKB/Swiss-Prot
  EpCAM_N UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
PhenoGen Epcam PhenoGen
PROSITE THYROGLOBULIN_1_1 UniProtKB/Swiss-Prot
  THYROGLOBULIN_1_2 UniProtKB/Swiss-Prot
SMART SM00211 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57610 UniProtKB/Swiss-Prot
UniProt A0A3Q4EHR5_MOUSE UniProtKB/TrEMBL
  A0A3Q4EI36_MOUSE UniProtKB/TrEMBL
  EPCAM_MOUSE UniProtKB/Swiss-Prot
  Q61512 ENTREZGENE
  Q99JW5 ENTREZGENE
UniProt Secondary Q61512 UniProtKB/Swiss-Prot