Atp6v1b2 (ATPase, H+ transporting, lysosomal V1 subunit B2) - Rat Genome Database

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Gene: Atp6v1b2 (ATPase, H+ transporting, lysosomal V1 subunit B2) Mus musculus
Analyze
Symbol: Atp6v1b2
Name: ATPase, H+ transporting, lysosomal V1 subunit B2
RGD ID: 732121
MGI Page MGI
Description: Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in synaptic vesicle lumen acidification. Located in several cellular components, including apical plasma membrane; microvillus; and ruffle. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study autosomal dominant congenital deafness with onychodystrophy and epilepsy. Human ortholog(s) of this gene implicated in autosomal dominant congenital deafness with onychodystrophy. Orthologous to human ATP6V1B2 (ATPase H+ transporting V1 subunit B2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI194269; AI790362; Atp6; Atp6b2; ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa; ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa, isoform 2; ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B; ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B, isoform 2; ATPase, H+ transporting, V1 subunit B; ATPase, H+ transporting, V1 subunit B, isoform 2; endomembrane proton pump 58 kDa subunit; HO5; HO57; lysosomal 56/58kDa; R74844; V-ATPase subunit B 2; V-type proton ATPase subunit B, brain isoform; vacuolar proton pump subunit B 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39869,541,388 - 69,566,370 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl869,541,298 - 69,566,363 (+)EnsemblGRCm39 Ensembl
GRCm38869,088,736 - 69,113,718 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,088,646 - 69,113,711 (+)EnsemblGRCm38mm10GRCm38
MGSCv37871,612,635 - 71,637,617 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36872,017,774 - 72,042,696 (+)NCBIMGSCv36mm8
Celera871,638,588 - 71,664,008 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map833.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2,2-tetramine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrolein  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
azoxystrobin  (ISO)
benzatropine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcidiol  (ISO)
carbon nanotube  (EXP,ISO)
chloropicrin  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP,ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
CU-O LINKAGE  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
diethyl malate  (ISO)
diethylstilbestrol  (EXP,ISO)
endosulfan  (ISO)
ethanol  (EXP)
fenpyroximate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
genistein  (EXP)
gentamycin  (ISO)
ginsenoside Rb1  (ISO)
haloperidol  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
lead diacetate  (EXP,ISO)
leflunomide  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (ISO)
Methylazoxymethanol acetate  (ISO)
microcystin-LR  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (ISO)
phenylpropanolamine  (EXP)
picoxystrobin  (ISO)
quartz  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
sodium arsenite  (EXP,ISO)
T-2 toxin  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (ISO)
thiram  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7945239   PMID:8741845   PMID:8772466   PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14681479  
PMID:14720510   PMID:15013950   PMID:15226823   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16177003   PMID:17114649   PMID:17392376   PMID:17634366   PMID:17898041  
PMID:17971301   PMID:17983586   PMID:18614564   PMID:18667600   PMID:18719589   PMID:18799693   PMID:18945877   PMID:19723774   PMID:20711468   PMID:20837476   PMID:21267068   PMID:21677750  
PMID:21873635   PMID:22245629   PMID:22467241   PMID:22794259   PMID:26177453   PMID:26442671   PMID:26490995   PMID:27384406   PMID:27568557   PMID:27626380   PMID:27899360   PMID:28793259  
PMID:29993276   PMID:30457570   PMID:30562941   PMID:30595499   PMID:30713523   PMID:31235642   PMID:31257146   PMID:32325033   PMID:32581705   PMID:33340069   PMID:34667084   PMID:34746137  
PMID:35318267   PMID:35550069   PMID:35624153   PMID:36293380   PMID:37142655   PMID:37628590   PMID:38355793  


Genomics

Comparative Map Data
Atp6v1b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39869,541,388 - 69,566,370 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl869,541,298 - 69,566,363 (+)EnsemblGRCm39 Ensembl
GRCm38869,088,736 - 69,113,718 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl869,088,646 - 69,113,711 (+)EnsemblGRCm38mm10GRCm38
MGSCv37871,612,635 - 71,637,617 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36872,017,774 - 72,042,696 (+)NCBIMGSCv36mm8
Celera871,638,588 - 71,664,008 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map833.88NCBI
ATP6V1B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38820,197,381 - 20,221,696 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl820,197,381 - 20,230,399 (+)EnsemblGRCh38hg38GRCh38
GRCh37820,054,892 - 20,079,207 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36820,098,984 - 20,123,487 (+)NCBINCBI36Build 36hg18NCBI36
Build 34820,098,983 - 20,123,485NCBI
Celera819,017,312 - 19,041,815 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef818,594,885 - 18,619,391 (+)NCBIHuRef
CHM1_1820,256,468 - 20,280,970 (+)NCBICHM1_1
T2T-CHM13v2.0820,462,474 - 20,486,792 (+)NCBIT2T-CHM13v2.0
Atp6v1b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81625,384,254 - 25,408,388 (-)NCBIGRCr8
mRatBN7.21620,617,515 - 20,641,651 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1620,617,518 - 20,641,745 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1623,985,269 - 24,010,794 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01627,416,771 - 27,440,870 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01623,350,578 - 23,376,103 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01622,326,537 - 22,350,143 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1622,326,529 - 22,350,155 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01622,221,011 - 22,244,664 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41622,320,425 - 22,344,445 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11622,320,425 - 22,344,443 (-)NCBI
Celera1620,593,372 - 20,617,306 (-)NCBICelera
Cytogenetic Map16p14NCBI
Atp6v1b2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540343,860,728 - 43,886,732 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540343,860,811 - 43,886,398 (+)NCBIChiLan1.0ChiLan1.0
ATP6V1B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2738,678,698 - 38,703,121 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1814,404,285 - 14,428,721 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0819,422,423 - 19,446,799 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1816,369,937 - 16,394,284 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl816,369,937 - 16,394,284 (+)Ensemblpanpan1.1panPan2
ATP6V1B2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12536,833,246 - 36,858,846 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2536,834,196 - 36,858,819 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2537,427,758 - 37,453,358 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02537,060,323 - 37,085,593 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2537,058,861 - 37,085,557 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12536,996,082 - 37,021,279 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02536,844,258 - 36,869,790 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02537,013,339 - 37,038,613 (-)NCBIUU_Cfam_GSD_1.0
Atp6v1b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494314,261,909 - 14,285,067 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365554,285,269 - 4,310,858 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365554,285,269 - 4,307,715 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP6V1B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl144,289,339 - 4,318,584 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1144,289,257 - 4,318,587 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2144,718,964 - 4,748,253 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP6V1B2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1818,264,210 - 18,289,951 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl818,264,329 - 18,293,444 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605223,963,087 - 23,988,457 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp6v1b2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475815,910,132 - 15,935,160 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475815,910,189 - 15,933,975 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp6v1b2
1918 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:831
Count of miRNA genes:545
Interacting mature miRNAs:651
Transcripts:ENSMUST00000006435, ENSMUST00000123290, ENSMUST00000125211, ENSMUST00000129797, ENSMUST00000153079, ENSMUST00000153680
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined866326836100326976Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3250657271740637Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84809006482090180Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84924559183245673Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85892810792928107Mouse
14746987Manh64_mmandible shape 64 (mouse)85050595884505958Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3250657271740637Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined866084397100084549Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84809006482090180Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85474046188740637Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84819016882190288Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85515925889159407Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3250657271740637Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6418673698186736Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86466617698666325Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85050595884505958Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85913640493136404Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85629887290298872Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86872247983326976Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83250657271740637Mouse
11039503Ccc4_mcolitis susceptibility in the Collaborative Cross 4 (mouse)86517423778002730Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86151347995513605Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85233484386334843Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84474791478748059Mouse

Markers in Region
RH135917  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,113,051 - 69,113,250UniSTSGRCm38
MGSCv37871,636,950 - 71,637,149UniSTSGRCm37
Celera871,663,341 - 71,663,540UniSTS
Cytogenetic Map8B3.3UniSTS
AI790362  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,112,876 - 69,112,965UniSTSGRCm38
MGSCv37871,636,775 - 71,636,864UniSTSGRCm37
Celera871,663,166 - 71,663,255UniSTS
Cytogenetic Map8B3.3UniSTS
Whitehead/MRC_RH8719.58UniSTS
U13838  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,112,639 - 69,112,811UniSTSGRCm38
MGSCv37871,636,538 - 71,636,710UniSTSGRCm37
Celera871,662,929 - 71,663,101UniSTS
Cytogenetic Map8B3.3UniSTS
Whitehead_YAC8 UniSTS
RH125116  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,112,736 - 69,112,820UniSTSGRCm38
MGSCv37871,636,635 - 71,636,719UniSTSGRCm37
Celera871,663,026 - 71,663,110UniSTS
Cytogenetic Map8B3.3UniSTS
Atp6v1b2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8B3.3UniSTS
cM Map8 UniSTS
Atp6b1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,102,777 - 69,103,284UniSTSGRCm38
MGSCv37871,626,676 - 71,627,183UniSTSGRCm37
Celera871,652,521 - 71,653,028UniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map8B3.3UniSTS
cM Map6 UniSTS
cM Map833.0UniSTS
Atp6b1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38869,102,777 - 69,103,413UniSTSGRCm38
MGSCv37871,626,676 - 71,627,312UniSTSGRCm37
Celera871,652,521 - 71,653,158UniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map8B3.3UniSTS
cM Map833.0UniSTS
Atp6v1b2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8B3.3UniSTS
cM Map8 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_007509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK146499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK166669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK192562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK215413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC046302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF437356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY499675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y12634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000006435   ⟹   ENSMUSP00000006435
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl869,541,298 - 69,566,363 (+)Ensembl
GRCm38.p6 Ensembl869,088,646 - 69,113,711 (+)Ensembl
Ensembl Acc Id: ENSMUST00000123290
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl869,554,865 - 69,555,715 (+)Ensembl
GRCm38.p6 Ensembl869,102,213 - 69,103,063 (+)Ensembl
Ensembl Acc Id: ENSMUST00000125211
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl869,541,441 - 69,549,238 (+)Ensembl
GRCm38.p6 Ensembl869,088,789 - 69,096,586 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129797
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl869,555,780 - 69,560,992 (+)Ensembl
GRCm38.p6 Ensembl869,103,128 - 69,108,340 (+)Ensembl
Ensembl Acc Id: ENSMUST00000153079
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl869,541,420 - 69,560,015 (+)Ensembl
GRCm38.p6 Ensembl869,088,768 - 69,107,363 (+)Ensembl
Ensembl Acc Id: ENSMUST00000153680
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl869,541,439 - 69,554,901 (+)Ensembl
GRCm38.p6 Ensembl869,088,787 - 69,102,249 (+)Ensembl
RefSeq Acc Id: NM_007509   ⟹   NP_031535
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39869,541,388 - 69,566,370 (+)NCBI
GRCm38869,088,736 - 69,113,718 (+)ENTREZGENE
MGSCv37871,612,635 - 71,637,617 (+)RGD
Celera871,638,588 - 71,664,008 (+)RGD
cM Map8 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_031535 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52411 (Get FASTA)   NCBI Sequence Viewer  
  AAH12497 (Get FASTA)   NCBI Sequence Viewer  
  AAH46302 (Get FASTA)   NCBI Sequence Viewer  
  AAH85300 (Get FASTA)   NCBI Sequence Viewer  
  ABS83522 (Get FASTA)   NCBI Sequence Viewer  
  AQS27596 (Get FASTA)   NCBI Sequence Viewer  
  BAE27215 (Get FASTA)   NCBI Sequence Viewer  
  BAE30197 (Get FASTA)   NCBI Sequence Viewer  
  BAE30303 (Get FASTA)   NCBI Sequence Viewer  
  BAE30526 (Get FASTA)   NCBI Sequence Viewer  
  BAE31441 (Get FASTA)   NCBI Sequence Viewer  
  BAE31479 (Get FASTA)   NCBI Sequence Viewer  
  BAE34845 (Get FASTA)   NCBI Sequence Viewer  
  BAE34860 (Get FASTA)   NCBI Sequence Viewer  
  BAE35206 (Get FASTA)   NCBI Sequence Viewer  
  BAE35300 (Get FASTA)   NCBI Sequence Viewer  
  BAE35536 (Get FASTA)   NCBI Sequence Viewer  
  BAE35612 (Get FASTA)   NCBI Sequence Viewer  
  BAE36047 (Get FASTA)   NCBI Sequence Viewer  
  BAE38930 (Get FASTA)   NCBI Sequence Viewer  
  BAE40674 (Get FASTA)   NCBI Sequence Viewer  
  BAE40934 (Get FASTA)   NCBI Sequence Viewer  
  BAE41031 (Get FASTA)   NCBI Sequence Viewer  
  CAA73182 (Get FASTA)   NCBI Sequence Viewer  
  EDL28730 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000006435
  ENSMUSP00000006435.8
GenBank Protein P62814 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_031535   ⟸   NM_007509
- UniProtKB: P50517 (UniProtKB/Swiss-Prot),   O09045 (UniProtKB/Swiss-Prot),   Q3U9Z0 (UniProtKB/Swiss-Prot),   Q3U7C8 (UniProtKB/Swiss-Prot),   Q3U791 (UniProtKB/Swiss-Prot),   Q3TWR0 (UniProtKB/Swiss-Prot),   Q3TVK6 (UniProtKB/Swiss-Prot),   Q3TL62 (UniProtKB/Swiss-Prot),   Q3TG74 (UniProtKB/Swiss-Prot),   Q3UAW7 (UniProtKB/Swiss-Prot),   P62814 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000006435   ⟸   ENSMUST00000006435
Protein Domains
ATP synthase A/B type C-terminal   ATPase F1/V1/A1 complex alpha/beta subunit   ATPase F1/V1/A1 complex alpha/beta subunit N-

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62814-F1-model_v2 AlphaFold P62814 1-511 view protein structure

Promoters
RGD ID:8667223
Promoter ID:EPDNEW_M11641
Type:initiation region
Name:Atp6v1b2_1
Description:Mus musculus ATPase, H+ transporting, lysosomal V1 subunit B2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38869,088,769 - 69,088,829EPDNEW
RGD ID:6842815
Promoter ID:MM_KWN:54600
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000063125,   OTTMUST00000063126,   OTTMUST00000063127,   OTTMUST00000063135,   OTTMUST00000063136
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36871,612,489 - 71,612,989 (+)MPROMDB
RGD ID:6842816
Promoter ID:MM_KWN:54602
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   Liver
Transcripts:OTTMUST00000063138,   UC009LWY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36871,625,801 - 71,626,301 (+)MPROMDB
RGD ID:6842817
Promoter ID:MM_KWN:54603
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour
Transcripts:OTTMUST00000063137
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36871,627,271 - 71,627,771 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109618 AgrOrtholog
Ensembl Genes ENSMUSG00000006273 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000006435 ENTREZGENE
  ENSMUST00000006435.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.12240 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ATP-synt_VA_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_a/bsu_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_F1/V1/A1_a/bsu_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_F1/V1/A1_a/bsu_nucl-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATPase_V1-cplx_bsu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-ATPase_su_B/beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11966 UniProtKB/Swiss-Prot
MGD MGI:109618 ENTREZGENE
NCBI Gene 11966 ENTREZGENE
PANTHER PTHR43389 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-TYPE PROTON ATPASE SUBUNIT B, BRAIN ISOFORM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ATP-synt_ab UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-synt_ab_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-synt_VA_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atp6v1b2 PhenoGen
PIRSF V-ATPsynth_beta/V-ATPase_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ATPASE_ALPHA_BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1S6GWG6_MOUSE UniProtKB/TrEMBL
  B0LAC8_MOUSE UniProtKB/TrEMBL
  O09045 ENTREZGENE
  P50517 ENTREZGENE
  P62814 ENTREZGENE
  Q3TG74 ENTREZGENE
  Q3TL62 ENTREZGENE
  Q3TVK6 ENTREZGENE
  Q3TWR0 ENTREZGENE
  Q3U791 ENTREZGENE
  Q3U7C8 ENTREZGENE
  Q3U9Z0 ENTREZGENE
  Q3UAW7 ENTREZGENE
  VATB2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O09045 UniProtKB/Swiss-Prot
  P50517 UniProtKB/Swiss-Prot
  Q3TG74 UniProtKB/Swiss-Prot
  Q3TL62 UniProtKB/Swiss-Prot
  Q3TVK6 UniProtKB/Swiss-Prot
  Q3TWR0 UniProtKB/Swiss-Prot
  Q3U791 UniProtKB/Swiss-Prot
  Q3U7C8 UniProtKB/Swiss-Prot
  Q3U9Z0 UniProtKB/Swiss-Prot
  Q3UAW7 UniProtKB/Swiss-Prot