Kiss1r (KISS1 receptor) - Rat Genome Database

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Gene: Kiss1r (KISS1 receptor) Mus musculus
Analyze
Symbol: Kiss1r
Name: KISS1 receptor
RGD ID: 731976
MGI Page MGI
Description: Enables G protein-coupled peptide receptor activity. Acts upstream of or within negative regulation of cell migration; negative regulation of cell population proliferation; and signal transduction. Located in cell surface. Is expressed in alimentary system; brain; genitourinary system; sensory organ; and thymus. Used to study hypogonadotropic hypogonadism 8 with or without anosmia. Human ortholog(s) of this gene implicated in central precocious puberty 1; hypogonadism; and hypogonadotropic hypogonadism 8 with or without anosmia. Orthologous to human KISS1R (KISS1 receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: G protein-coupled receptor 54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; Gpr; Gpr54; KiSS-1; kiSS-1 receptor; kiSS-1R; kisspeptins receptor; metastin receptor; mOT7T175; orphan G protein-coupled receptor 54
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,752,786 - 79,759,922 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,752,805 - 79,758,107 (+)EnsemblGRCm39 Ensembl
GRCm381079,916,952 - 79,924,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,916,971 - 79,922,273 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,379,716 - 79,385,018 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,320,100 - 79,325,312 (+)NCBIMGSCv36mm8
Celera1080,931,781 - 80,937,083 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adrenal cortex morphology  (IAGP)
abnormal anogenital distance  (IAGP)
abnormal blood homeostasis  (IAGP)
abnormal bone structure  (IEA)
abnormal branching of the mammary ductal tree  (IAGP)
abnormal epididymis morphology  (IEA)
abnormal estrous cycle  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal fertility/fecundity  (IAGP)
abnormal follicle stimulating hormone level  (IAGP)
abnormal hypothalamus morphology  (IAGP)
abnormal kidney morphology  (IEA)
abnormal luteinizing hormone level  (IAGP)
abnormal male reproductive system morphology  (IAGP)
abnormal oogenesis  (IAGP)
abnormal ovary morphology  (IEA)
abnormal reproductive system morphology  (IAGP)
abnormal reproductive system physiology  (IAGP)
abnormal response/metabolism to endogenous compounds  (IAGP)
abnormal seminal vesicle morphology  (IEA)
abnormal sexual interaction  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal testis morphology  (IEA)
abnormal uterus morphology  (IEA)
abnormal vagina development  (IAGP)
absent corpus luteum  (IAGP)
absent epididymis  (IEA)
absent estrous cycle  (IAGP)
absent male preputial gland  (IAGP)
absent mature ovarian follicles  (IAGP)
absent ovarian follicles  (IAGP)
absent ovary  (IEA)
absent prostate gland  (IAGP)
absent seminal vesicle  (IAGP)
absent sexual maturation  (IAGP)
absent testes  (IEA)
absent uterus  (IEA)
anovulation  (IAGP)
arrest of male meiosis  (IAGP)
arrest of spermatogenesis  (IAGP)
azoospermia  (IAGP)
constricted vagina orifice  (IAGP)
decreased adrenal gland weight  (IAGP)
decreased basophil cell number  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IEA)
decreased bone mineral density  (IEA)
decreased circulating cholesterol level  (IAGP)
decreased circulating estradiol level  (IAGP)
decreased circulating follicle stimulating hormone level  (IAGP)
decreased circulating gonadotropin level  (IAGP)
decreased circulating luteinizing hormone level  (IAGP)
decreased circulating testosterone level  (IAGP)
decreased circulating total protein level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased eosinophil cell number  (IAGP)
decreased epididymis weight  (IAGP)
decreased heart weight  (IEA)
decreased kidney weight  (IAGP)
decreased lean body mass  (IEA)
decreased Leydig cell number  (IAGP)
decreased liver weight  (IAGP)
decreased locomotor activity  (IEA)
decreased luteinizing hormone level  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased monocyte cell number  (IAGP)
decreased motor neuron number  (IAGP)
decreased neuron number  (IAGP)
decreased neutrophil cell number  (IAGP)
decreased ovary weight  (IAGP)
decreased prostate gland weight  (IAGP)
decreased seminal vesicle weight  (IAGP)
decreased testis weight  (IAGP)
decreased uterus weight  (IAGP)
delayed balanopreputial separation  (IAGP)
delayed sexual maturation  (IAGP)
delayed vaginal opening  (IAGP)
failure of ejaculation  (IAGP)
female infertility  (IAGP)
increased atretic ovarian follicle number  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased circulating alkaline phosphatase level  (IAGP)
increased circulating creatinine level  (IEA)
increased circulating glucose level  (IAGP)
increased circulating serum albumin level  (IAGP)
increased spleen weight  (IAGP)
increased thymus weight  (IAGP)
increased total body fat amount  (IEA)
infertility  (IAGP)
male infertility  (IAGP)
mammary gland hypoplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
oligozoospermia  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
reduced male mating frequency  (IAGP)
retention of the adrenal gland x-zone  (IAGP)
seminal vesicle hypoplasia  (IAGP)
seminiferous tubule degeneration  (IAGP)
small epididymis  (IAGP)
small gonad  (IAGP)
small kidney  (IEA)
small male preputial gland  (IAGP)
small ovary  (IAGP)
small penis  (IAGP)
small prostate gland  (IAGP)
small seminal vesicle  (IAGP)
small seminiferous tubules  (IAGP)
small testis  (IAGP)
small uterine cervix  (IAGP)
small uterus  (IAGP)
small vagina  (IAGP)
thrombocytopenia  (IAGP)
uterus hypoplasia  (IAGP)
vagina atresia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. de Roux N, etal., Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10972-6. Epub 2003 Aug 27.
2. High tumoral levels of Kiss1 and G-protein-coupled receptor 54 expression are correlated with poor prognosis of estrogen receptor-positive breast tumors. Marot D, etal., Endocr Relat Cancer. 2007 Sep;14(3):691-702.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. MGD IEA MGD IEA
6. Metastin (KISS-1) and metastin-coupled receptor (GPR54) expression in transitional cell carcinoma of the bladder. Nicolle G, etal., Ann Oncol. 2007 Mar;18(3):605-7. Epub 2006 Dec 12.
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Metastin receptor is overexpressed in papillary thyroid cancer and activates MAP kinase in thyroid cancer cells. Ringel MD, etal., J Clin Endocrinol Metab. 2002 May;87(5):2399.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11414709   PMID:12359743   PMID:12477932   PMID:14573733   PMID:14652023   PMID:15489334   PMID:15519892  
PMID:15665093   PMID:16141072   PMID:16141073   PMID:16339030   PMID:16602821   PMID:17595226   PMID:17595229   PMID:17698953   PMID:17699664   PMID:17728535   PMID:17978050   PMID:18450966  
PMID:18483150   PMID:18625716   PMID:18753370   PMID:18948403   PMID:19141986   PMID:19840236   PMID:19966055   PMID:19966188   PMID:20083160   PMID:20109523   PMID:20152817   PMID:20375015  
PMID:20573904   PMID:20886089   PMID:21156837   PMID:21267068   PMID:21325509   PMID:21362171   PMID:21516099   PMID:21527035   PMID:21756268   PMID:21852382   PMID:21873635   PMID:22067321  
PMID:22132116   PMID:22202164   PMID:22262891   PMID:22340076   PMID:22778229   PMID:23337528   PMID:23595904   PMID:23770611   PMID:24051579   PMID:24092638   PMID:24130552   PMID:24194600  
PMID:24416028   PMID:24422632   PMID:24599473   PMID:24703698   PMID:24812663   PMID:24830702   PMID:24877624   PMID:24877631   PMID:24885574   PMID:24937427   PMID:24956377   PMID:24982149  
PMID:25147978   PMID:25301053   PMID:25322463   PMID:25422875   PMID:25468546   PMID:25756309   PMID:26172029   PMID:26273529   PMID:26377475   PMID:26384646   PMID:26418326   PMID:26755241  
PMID:26879207   PMID:27158817   PMID:27245315   PMID:27364226   PMID:27601011   PMID:27626380   PMID:27649089   PMID:28154160   PMID:28235895   PMID:28339602   PMID:28411243   PMID:28475692  
PMID:29434234   PMID:29593567   PMID:29931449   PMID:29948931   PMID:30565563   PMID:30668693   PMID:31442544   PMID:31619585   PMID:31914628   PMID:33899117   PMID:34524460   PMID:34896241  
PMID:38355793   PMID:38976640  


Genomics

Comparative Map Data
Kiss1r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,752,786 - 79,759,922 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,752,805 - 79,758,107 (+)EnsemblGRCm39 Ensembl
GRCm381079,916,952 - 79,924,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,916,971 - 79,922,273 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,379,716 - 79,385,018 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,320,100 - 79,325,312 (+)NCBIMGSCv36mm8
Celera1080,931,781 - 80,937,083 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
KISS1R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819917,333 - 921,005 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl19917,287 - 921,005 (+)EnsemblGRCh38hg38GRCh38
GRCh3719917,333 - 921,005 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619868,358 - 872,013 (+)NCBINCBI36Build 36hg18NCBI36
Build 3419868,502 - 872,001NCBI
Celera19849,702 - 853,371 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19690,992 - 694,661 (+)NCBIHuRef
CHM1_119916,929 - 920,598 (+)NCBICHM1_1
T2T-CHM13v2.019880,072 - 883,744 (+)NCBIT2T-CHM13v2.0
Kiss1r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,435,766 - 10,439,424 (-)NCBIGRCr8
mRatBN7.279,785,135 - 9,790,283 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,785,135 - 9,788,793 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,667,118 - 12,670,776 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,542,438 - 14,546,096 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,403,615 - 12,407,273 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,606,210 - 12,609,868 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,606,210 - 12,609,868 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,776,069 - 12,779,416 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,297,840 - 11,301,187 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1711,297,839 - 11,301,187 (-)NCBI
Celera77,960,079 - 7,963,737 (-)NCBICelera
Cytogenetic Map7q11NCBI
Kiss1r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554956,918,632 - 6,921,891 (-)NCBIChiLan1.0ChiLan1.0
KISS1R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,247,832 - 5,251,613 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,487,168 - 4,491,344 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v019211,563 - 215,332 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.119889,152 - 891,739 (+)NCBIpanpan1.1PanPan1.1panPan2
KISS1R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,756,046 - 57,758,940 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2057,756,197 - 57,758,940 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,558,011 - 57,560,904 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,498,289 - 58,501,191 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,498,289 - 58,501,191 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,553,142 - 57,556,035 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02058,032,791 - 58,035,680 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,235,792 - 58,238,682 (-)NCBIUU_Cfam_GSD_1.0
Kiss1r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,446,523 - 217,452,872 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588384,195 - 386,820 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588384,195 - 387,625 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KISS1R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,472,362 - 77,479,204 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,472,361 - 77,479,204 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,518,436 - 77,525,279 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2q21-q24NCBI
KISS1R
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16666,386 - 670,833 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl6667,210 - 670,563 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660818,246,899 - 8,251,354 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kiss1r
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,677,395 - 7,680,355 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,677,467 - 7,680,508 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Kiss1r
118 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:89
Interacting mature miRNAs:91
Transcripts:ENSMUST00000045529
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106684818792258673Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105109149085091639Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75338568109338767Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105851696992517096Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
14746991Manh68_mmandible shape 68 (mouse)105228049786280497Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1270405184079784Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101270405184079784Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104933801283338157Mouse
1301380Cia8_mcollagen induced arthritis QTL 8 (mouse)Not determined105149340082491121Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101010826587401095Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1044876096115935905Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073506901107507047Mouse
4142107Obrq12_mobesity resistance QTL 12 (mouse)Not determined7398721682491121Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106549093899491121Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102287589991035862Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045476096120635905Mouse
11251717Siim1_mstress induced immobility 1 (mouse)1078381268112381268Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
1357740Obsty3_mobesity 3 (mouse)Not determined108235478116190980Mouse
13208560Wght9_mweight 9 (mouse)1059835822120835905Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1270405184079784Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101270405184079784Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined104984822283848397Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106549093899491121Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101270405184079784Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067335830111735905Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1270405184079784Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101270405184079784Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024675898121035905Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined104984818783848412Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1063935779115935905Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075338568109338767Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4672040382491121Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined104984822283848397Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined104984818783848412Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined104984818783848412Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105109149085091639Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021408154114217230Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106549093899491121Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075338568109338767Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1270405184079784Mouse

Markers in Region
Kiss1r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10C1UniSTS
cM Map1039.72UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001359010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006513079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_380346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC151846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF343726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY044228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE949364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU532436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU532437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU879091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GU075727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000045529   ⟹   ENSMUSP00000040516
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1079,752,805 - 79,758,107 (+)Ensembl
GRCm38.p6 Ensembl1079,916,971 - 79,922,273 (+)Ensembl
Ensembl Acc Id: ENSMUST00000219745   ⟹   ENSMUSP00000151936
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1079,754,508 - 79,757,859 (+)Ensembl
GRCm38.p6 Ensembl1079,918,674 - 79,922,025 (+)Ensembl
Ensembl Acc Id: ENSMUST00000219883
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1079,752,805 - 79,758,104 (+)Ensembl
GRCm38.p6 Ensembl1079,916,971 - 79,922,270 (+)Ensembl
RefSeq Acc Id: NM_001359010   ⟹   NP_001345939
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,752,805 - 79,758,107 (+)NCBI
GRCm381079,916,971 - 79,922,273 (+)NCBI
Sequence:
RefSeq Acc Id: NM_053244   ⟹   NP_444474
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,752,805 - 79,758,107 (+)NCBI
GRCm381079,916,971 - 79,922,273 (+)NCBI
MGSCv371079,379,716 - 79,385,018 (+)RGD
Celera1080,931,781 - 80,937,083 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006513076   ⟹   XP_006513139
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,754,339 - 79,759,922 (+)NCBI
GRCm381079,916,952 - 79,924,088 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006513077   ⟹   XP_006513140
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,754,339 - 79,759,922 (+)NCBI
GRCm381079,918,385 - 79,924,088 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006513079   ⟹   XP_006513142
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,754,345 - 79,759,922 (+)NCBI
GRCm381079,918,385 - 79,924,088 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004936040
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,752,786 - 79,759,922 (+)NCBI
Sequence:
RefSeq Acc Id: XR_380346
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391079,754,345 - 79,759,922 (+)NCBI
GRCm381079,918,385 - 79,924,088 (+)NCBI
Sequence:
RefSeq Acc Id: NP_444474   ⟸   NM_053244
- Peptide Label: isoform 1
- UniProtKB: Q8K3P2 (UniProtKB/Swiss-Prot),   Q91V45 (UniProtKB/Swiss-Prot),   B2CP06 (UniProtKB/TrEMBL),   B2CP05 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006513140   ⟸   XM_006513077
- Peptide Label: isoform X1
- UniProtKB: Q8K3P2 (UniProtKB/Swiss-Prot),   Q91V45 (UniProtKB/Swiss-Prot),   B2CP06 (UniProtKB/TrEMBL),   B2CP05 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006513142   ⟸   XM_006513079
- Peptide Label: isoform X2
- UniProtKB: C5H7S2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006513139   ⟸   XM_006513076
- Peptide Label: isoform X1
- UniProtKB: Q8K3P2 (UniProtKB/Swiss-Prot),   Q91V45 (UniProtKB/Swiss-Prot),   B2CP06 (UniProtKB/TrEMBL),   B2CP05 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001345939   ⟸   NM_001359010
- Peptide Label: isoform 2
Ensembl Acc Id: ENSMUSP00000040516   ⟸   ENSMUST00000045529
Ensembl Acc Id: ENSMUSP00000151936   ⟸   ENSMUST00000219745
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91V45-F1-model_v2 AlphaFold Q91V45 1-396 view protein structure

Promoters
RGD ID:6819484
Promoter ID:MM_KWN:4799
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_053244,   NM_177994
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361079,379,616 - 79,381,382 (+)MPROMDB
RGD ID:8672578
Promoter ID:EPDNEW_M14320
Type:single initiation site
Name:Kiss1r_1
Description:Mus musculus KISS1 receptor , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381079,916,971 - 79,917,031EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2148793 AgrOrtholog
Ensembl Genes ENSMUSG00000035773 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000045529 ENTREZGENE
  ENSMUST00000045529.3 UniProtKB/Swiss-Prot
  ENSMUST00000219745 ENTREZGENE
  ENSMUST00000219745.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KiSS_1_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:114229 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2148793 ENTREZGENE
NCBI Gene 114229 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KISS-1 RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Kiss1r PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KISS1RECEPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2CP05 ENTREZGENE, UniProtKB/TrEMBL
  B2CP06 ENTREZGENE, UniProtKB/TrEMBL
  C5H7S2 ENTREZGENE, UniProtKB/TrEMBL
  KISSR_MOUSE UniProtKB/Swiss-Prot
  Q8K3P2 ENTREZGENE
  Q91V45 ENTREZGENE
UniProt Secondary Q8K3P2 UniProtKB/Swiss-Prot