GCLM Human (-)-demecolcine decreases expression EXP 6480464 Demecolcine results in decreased expression of GCLM mRNA CTD PMID:23649840 GCLM Human (-)-epigallocatechin 3-gallate increases expression ISO Gclm (Mus musculus) 6480464 epigallocatechin gallate results in increased expression of GCLM mRNA CTD PMID:25585349 GCLM Human (E)-cinnamyl alcohol increases expression EXP 6480464 cinnamyl alcohol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... GCLM Human (R)-lipoic acid increases expression EXP 6480464 Thioctic Acid results in increased expression of GCLM mRNA and Thioctic Acid results in increased expression of GCLM protein CTD PMID:16249512 and PMID:26365678 GCLM Human (R)-lipoic acid multiple interactions EXP 6480464 Thioctic Acid promotes the reaction [Cadmium Chloride results in increased expression of GCLM mRNA] and Thioctic Acid promotes the reaction [Cadmium Chloride results in increased expression of GCLM protein] CTD PMID:26365678 GCLM Human (R)-lipoic acid multiple interactions ISO Gclm (Rattus norvegicus) 6480464 Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM mRNA] and Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM protein] CTD PMID:32061141 GCLM Human (R,R,R)-alpha-tocopherol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 GCLM Human (R,R,R)-alpha-tocopherol multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLM mRNA CTD PMID:24530478 GCLM Human (S)-colchicine multiple interactions ISO Gclm (Mus musculus) 6480464 Colchicine inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM mRNA] CTD PMID:37573684 GCLM Human (S)-naringenin multiple interactions EXP 6480464 NFE2L2 protein affects the reaction [naringenin results in increased expression of GCLM protein] CTD PMID:31254498 GCLM Human (S)-naringenin increases expression EXP 6480464 naringenin results in increased expression of GCLM protein CTD PMID:31254498 GCLM Human 1,1'-azobis(N,N-dimethylformamide) increases expression ISO Gclm (Rattus norvegicus) 6480464 Diamide results in increased expression of GCLM mRNA and Diamide results in increased expression of GCLM protein CTD PMID:15115889 GCLM Human 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO Gclm (Rattus norvegicus) 6480464 o and p'-DDT affects the expression of GCLM mRNA CTD PMID:17984292 GCLM Human 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO Gclm (Mus musculus) 6480464 o and p'-DDT affects the expression of GCLM mRNA CTD PMID:18925944 GCLM Human 1,1-dichloroethene decreases expression ISO Gclm (Mus musculus) 6480464 vinylidene chloride results in decreased expression of GCLM mRNA CTD PMID:26682919 GCLM Human 1,2-dimethylhydrazine affects expression ISO Gclm (Mus musculus) 6480464 1 and 2-Dimethylhydrazine affects the expression of GCLM mRNA CTD PMID:22206623 GCLM Human 1,3-benzothiazole-2-thiol increases expression EXP 6480464 captax results in increased expression of GCLM mRNA CTD PMID:23999411 and PMID:24211530 GCLM Human 1,3-dichloropropan-2-ol increases expression ISO Gclm (Rattus norvegicus) 6480464 1 and 3-dichloro-2-propanol results in increased expression of GCLM mRNA CTD PMID:26143167 GCLM Human 1,4-benzoquinone increases expression EXP 6480464 quinone results in increased expression of GCLM protein CTD PMID:21059386 GCLM Human 1,4-phenylenediamine increases expression EXP 6480464 4-phenylenediamine results in increased expression of GCLM mRNA CTD PMID:16314067 more ... GCLM Human 1-bromopropane multiple interactions ISO Gclm (Mus musculus) 6480464 NFE2L2 promotes the reaction [1-bromopropane results in increased expression of GCLM mRNA] CTD PMID:20211940 GCLM Human 1-bromopropane increases expression ISO Gclm (Mus musculus) 6480464 1-bromopropane results in increased expression of GCLM mRNA CTD PMID:20211940 GCLM Human 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of GCLM mRNA CTD PMID:20146380 more ... GCLM Human 1-chloro-2,4-dinitrobenzene multiple interactions EXP 6480464 NFE2L2 protein affects the reaction [Dinitrochlorobenzene results in increased expression of GCLM mRNA] CTD PMID:27965148 GCLM Human 1-fluoro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrofluorobenzene results in increased expression of GCLM mRNA CTD PMID:23999411 GCLM Human 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression ISO Gclm (Mus musculus) 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:31187328 GCLM Human 1-naphthyl isothiocyanate increases expression ISO Gclm (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of GCLM mRNA CTD PMID:20551477 GCLM Human 1-naphthyl isothiocyanate decreases expression ISO Gclm (Mus musculus) 6480464 1-Naphthylisothiocyanate results in decreased expression of GCLM mRNA CTD PMID:37348807 GCLM Human 1-naphthyl isothiocyanate multiple interactions ISO Gclm (Mus musculus) 6480464 [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of GCLM protein and tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of GCLM mRNA] CTD PMID:37348807 GCLM Human 1-naphthyl isothiocyanate multiple interactions EXP 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of GCLM mRNA CTD PMID:27344345 GCLM Human 17alpha-ethynylestradiol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Ethinyl Estradiol co-treated with epomediol] results in increased activity of GCLM protein CTD PMID:12071332 GCLM Human 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of GCLM mRNA CTD PMID:20106945 and PMID:31614463 GCLM Human 17beta-estradiol increases expression ISO Gclm (Rattus norvegicus) 6480464 Estradiol results in increased expression of GCLM mRNA CTD PMID:32145629 GCLM Human 17beta-estradiol affects expression ISO Gclm (Rattus norvegicus) 6480464 Estradiol affects the expression of GCLM mRNA CTD PMID:22389237 GCLM Human 17beta-estradiol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 GCLM Human 2,2',4,4',5,5'-hexachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:38568856 GCLM Human 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 [2 more ... CTD PMID:25305463 GCLM Human 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Gclm (Mus musculus) 6480464 2 more ... CTD PMID:30294300 GCLM Human 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO Gclm (Mus musculus) 6480464 GCLM protein affects the reaction [2 more ... CTD PMID:25797475 GCLM Human 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:25305463 GCLM Human 2,2',5,5'-tetrachlorobiphenyl increases expression ISO Gclm (Rattus norvegicus) 6480464 2 more ... CTD PMID:23829299 GCLM Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Gclm (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of GCLM mRNA CTD PMID:18163543 GCLM Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Gclm (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of GCLM mRNA CTD PMID:33387578 GCLM Human 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of GCLM mRNA CTD PMID:11489354 more ... GCLM Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Gclm (Mus musculus) 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of GCLM mRNA CTD PMID:25975270 GCLM Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Gclm (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of GCLM mRNA CTD PMID:21570461 GCLM Human 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of GCLM mRNA CTD PMID:22298810 GCLM Human 2,3,7,8-tetrachlorodibenzodioxine decreases response to substance ISO Gclm (Mus musculus) 6480464 GCLM results in decreased susceptibility to Tetrachlorodibenzodioxin CTD PMID:22082335 GCLM Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Gclm (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of GCLM mRNA CTD PMID:21215274 GCLM Human 2,3-dimethoxynaphthalene-1,4-dione decreases response to substance ISO Gclm (Mus musculus) 6480464 [GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to 2 more ... CTD PMID:23315585 GCLM Human 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of GCLM mRNA CTD PMID:22609641 GCLM Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Gclm (Mus musculus) 6480464 2 more ... CTD PMID:38648751 GCLM Human 2-(chloromethyl)pyridine increases expression EXP 6480464 2-chloromethylpyridine results in increased expression of GCLM mRNA CTD PMID:26198647 GCLM Human 2-acetamidofluorene multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCLM mRNA CTD PMID:16158176 GCLM Human 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO Gclm (Mus musculus) 6480464 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLM mRNA] more ... CTD PMID:28887131 and PMID:35691465 GCLM Human 2-bromo-2-(bromomethyl)pentanedinitrile increases expression EXP 6480464 1 more ... CTD PMID:23999411 and PMID:27965148 GCLM Human 2-Ethylhexyl acrylate increases expression EXP 6480464 2-ethylhexyl acrylate results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human 2-hydroxyethyl methacrylate increases expression EXP 6480464 hydroxyethyl methacrylate results in increased expression of GCLM mRNA and hydroxyethyl methacrylate results in increased expression of GCLM protein CTD PMID:30497689 GCLM Human 2-hydroxypropanoic acid increases expression EXP 6480464 Lactic Acid results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human 2-palmitoylglycerol increases expression EXP 6480464 2-palmitoylglycerol results in increased expression of GCLM mRNA CTD PMID:37199045 GCLM Human 2-tert-butylhydroquinone increases expression ISO Gclm (Mus musculus) 6480464 2-tert-butylhydroquinone results in increased expression of GCLM mRNA CTD PMID:12007577 more ... GCLM Human 2-tert-butylhydroquinone decreases expression EXP 6480464 2-tert-butylhydroquinone results in decreased expression of GCLM mRNA CTD PMID:35724838 GCLM Human 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA] more ... CTD PMID:24632381 and PMID:25305463 GCLM Human 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of GCLM mRNA CTD PMID:12081989 and PMID:25003661 GCLM Human 2-tert-butylhydroquinone multiple interactions ISO Gclm (Mus musculus) 6480464 NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of GCLM mRNA] CTD PMID:19328227 GCLM Human 2-tert-butylhydroquinone increases expression ISO Gclm (Rattus norvegicus) 6480464 2-tert-butylhydroquinone results in increased expression of GCLM mRNA CTD PMID:10978506 GCLM Human 3,7-dihydropurine-6-thione increases expression EXP 6480464 Mercaptopurine results in increased expression of GCLM mRNA CTD PMID:18222062 GCLM Human 3-Hydroxybenzo[a]pyrene increases expression EXP 6480464 3-hydroxybenzo(a)pyrene results in increased expression of GCLM mRNA CTD PMID:26238291 GCLM Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Gclm (Mus musculus) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of GCLM mRNA CTD PMID:33412187 GCLM Human 3-phenylprop-2-enal multiple interactions EXP 6480464 [cinnamaldehyde results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA CTD PMID:20351055 GCLM Human 3-phenylprop-2-enal increases expression EXP 6480464 cinnamaldehyde results in increased expression of GCLM mRNA CTD PMID:17178418 more ... GCLM Human 3H-1,2-dithiole-3-thione affects expression ISO Gclm (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione affects the expression of GCLM mRNA CTD PMID:19162173 GCLM Human 3H-1,2-dithiole-3-thione multiple interactions ISO Gclm (Mus musculus) 6480464 [1 and 2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA CTD PMID:22495766 GCLM Human 4,4'-methylene-bis-(2-chloroaniline) increases expression EXP 6480464 Methylenebis(chloroaniline) results in increased expression of GCLM mRNA CTD PMID:26198647 GCLM Human 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of GCLM protein CTD PMID:34186270 GCLM Human 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression EXP 6480464 Oxazolone results in increased expression of GCLM mRNA CTD PMID:23999411 GCLM Human 4-hydroxy-TEMPO multiple interactions EXP 6480464 NFE2L2 protein affects the reaction [tempol inhibits the reaction [lipopolysaccharide more ... CTD PMID:38454815 GCLM Human 4-hydroxynon-2-enal increases expression ISO Gclm (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased expression of GCLM mRNA CTD PMID:19191707 GCLM Human 4-hydroxyphenyl retinamide increases expression ISO Gclm (Mus musculus) 6480464 Fenretinide results in increased expression of GCLM mRNA CTD PMID:28973697 GCLM Human 4-nitro-1,2-phenylenediamine increases expression EXP 6480464 1 and 2-diamino-4-nitrobenzene results in increased expression of GCLM mRNA CTD PMID:26198647 GCLM Human 4-nitrobenzyl bromide increases expression EXP 6480464 4-nitrobenzyl bromide results in increased expression of GCLM mRNA CTD PMID:23999411 GCLM Human 4-phenyl-3-furoxancarbonitrile increases expression EXP 6480464 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLM mRNA CTD PMID:22851183 GCLM Human 5-fluorouracil affects response to substance EXP 6480464 GCLM protein affects the susceptibility to Fluorouracil CTD PMID:16217747 GCLM Human 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO Gclm (Rattus norvegicus) 6480464 6-chloro-2 more ... CTD PMID:33661552 GCLM Human 7,8-dihydroxycoumarin increases expression EXP 6480464 daphnetin results in increased expression of GCLM protein CTD PMID:30738023 GCLM Human 7beta-aminocephalosporanic acid increases expression EXP 6480464 7-aminocephalosporanic acid results in increased expression of GCLM mRNA CTD PMID:24211530 GCLM Human [6]-Shogaol increases expression EXP 6480464 shogaol metabolite results in increased expression of GCLM protein and shogaol results in increased expression of GCLM protein CTD PMID:25148906 GCLM Human abietic acid increases expression EXP 6480464 abietic acid results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human acetylcholine affects response to substance EXP 6480464 GCLM gene SNP affects the susceptibility to Acetylcholine CTD PMID:12975258 GCLM Human acrolein increases expression ISO Gclm (Mus musculus) 6480464 Acrolein results in increased expression of GCLM mRNA CTD PMID:12763045 GCLM Human acrolein multiple interactions EXP 6480464 CLDN1 protein promotes the reaction [Acrolein results in increased expression of GCLM mRNA] CTD PMID:38142011 GCLM Human acrolein increases expression ISO Gclm (Rattus norvegicus) 6480464 Acrolein results in increased expression of GCLM mRNA CTD PMID:38090360 GCLM Human acrolein increases expression EXP 6480464 Acrolein results in increased expression of GCLM mRNA CTD PMID:24211530 GCLM Human acrylamide multiple interactions EXP 6480464 salvin inhibits the reaction [Acrylamide results in decreased expression of GCLM mRNA] CTD PMID:28159594 GCLM Human acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of GCLM mRNA CTD PMID:32763439 GCLM Human acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of GCLM mRNA CTD PMID:28159594 GCLM Human actinomycin D multiple interactions EXP 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of GCLM protein CTD PMID:38460933 GCLM Human Aescin increases expression ISO Gclm (Mus musculus) 6480464 Escin results in increased expression of GCLM protein CTD PMID:36905866 GCLM Human Aescin multiple interactions ISO Gclm (Mus musculus) 6480464 Escin inhibits the reaction [Dietary Fats results in decreased expression of GCLM protein] and NFE2L2 protein affects the reaction [Escin inhibits the reaction [Dietary Fats results in decreased expression of GCLM protein]] CTD PMID:36905866 GCLM Human Aescin multiple interactions EXP 6480464 Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein] CTD PMID:36905866 GCLM Human aflatoxin B1 decreases expression ISO Gclm (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of GCLM mRNA CTD PMID:19770486 GCLM Human aflatoxin B1 increases expression ISO Gclm (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of GCLM mRNA CTD PMID:23630614 and PMID:25378103 GCLM Human AL 8810 multiple interactions EXP 6480464 AL 8810 inhibits the reaction [fluprostenol promotes the reaction [Oxidopamine results in increased expression of GCLM mRNA]] CTD PMID:33486071 GCLM Human alachlor increases expression ISO Gclm (Rattus norvegicus) 6480464 alachlor results in increased expression of GCLM protein CTD PMID:14563481 GCLM Human aldehydo-D-glucose multiple interactions ISO Gclm (Mus musculus) 6480464 [Glucose co-treated with gastrodin] affects the expression of GCLM mRNA CTD PMID:33764184 GCLM Human aldehydo-D-glucose multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Glucose co-treated with gastrodin] affects the expression of GCLM mRNA CTD PMID:33764184 GCLM Human all-trans-retinoic acid decreases expression ISO Gclm (Rattus norvegicus) 6480464 Tretinoin results in decreased expression of GCLM mRNA and Tretinoin results in decreased expression of GCLM protein CTD PMID:30267739 GCLM Human all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of GCLM mRNA CTD PMID:33167477 GCLM Human all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of GCLM mRNA CTD PMID:38040126 GCLM Human alpha,alpha-trehalose multiple interactions ISO Gclm (Rattus norvegicus) 6480464 Trehalose inhibits the reaction [cadmium acetate results in increased expression of GCLM protein] CTD PMID:29140578 GCLM Human alpha-hexylcinnamaldehyde increases expression EXP 6480464 hexyl cinnamic aldehyde results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human alpha-Solamarine multiple interactions ISO Gclm (Mus musculus) 6480464 alpha-solamargine inhibits the reaction [Sevoflurane results in decreased expression of GCLM mRNA] CTD PMID:35350913 GCLM Human aminoguanidine multiple interactions ISO Gclm (Mus musculus) 6480464 pimagedine inhibits the reaction [Spermidine results in increased expression of GCLM mRNA] CTD PMID:12763045 GCLM Human amiodarone increases expression EXP 6480464 Amiodarone results in increased expression of GCLM mRNA CTD PMID:36586010 GCLM Human amlexanox multiple interactions ISO Gclm (Mus musculus) 6480464 [Acetaminophen co-treated with amlexanox co-treated with dorsomorphin] affects the expression of GCLM mRNA CTD PMID:31697998 GCLM Human ammonium chloride affects expression ISO Gclm (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of GCLM mRNA CTD PMID:16483693 GCLM Human ammonium hexachloroplatinate increases expression EXP 6480464 ammonium hexachloroplatinate results in increased expression of GCLM mRNA CTD PMID:24211530 GCLM Human ampicillin increases expression EXP 6480464 Ampicillin results in increased expression of GCLM mRNA CTD PMID:22609641 GCLM Human ampicillin decreases expression EXP 6480464 Ampicillin results in decreased expression of GCLM mRNA CTD PMID:21632981 GCLM Human andrographolide increases expression ISO Gclm (Rattus norvegicus) 6480464 andrographolide results in increased expression of GCLM mRNA and andrographolide results in increased expression of GCLM protein CTD PMID:25110055 and PMID:29355602 GCLM Human andrographolide decreases expression EXP 6480464 andrographolide results in decreased expression of GCLM mRNA CTD PMID:35724838 GCLM Human andrographolide multiple interactions EXP 6480464 [andrographolide co-treated with TNF protein] results in increased expression of GCLM mRNA CTD PMID:35724838 GCLM Human andrographolide increases expression EXP 6480464 andrographolide results in increased expression of GCLM protein CTD PMID:29355602 GCLM Human andrographolide increases expression ISO Gclm (Mus musculus) 6480464 andrographolide results in increased expression of GCLM protein CTD PMID:29355602 GCLM Human andrographolide multiple interactions ISO Gclm (Mus musculus) 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GCLM mRNA and andrographolide inhibits the reaction [Acetaminophen results in decreased expression of GCLM mRNA] CTD PMID:19737545 and PMID:29355602 GCLM Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [[Acetaminophen co-treated with Quercetin] results in increased expression of GCLM mRNA] more ... CTD PMID:25881548 GCLM Human anthra[1,9-cd]pyrazol-6(2H)-one decreases activity EXP 6480464 pyrazolanthrone results in decreased activity of GCLM protein CTD PMID:16972261 GCLM Human antimonite multiple interactions EXP 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GCLM mRNA CTD PMID:32076005 GCLM Human antimycin A increases expression EXP 6480464 Antimycin A results in increased expression of GCLM mRNA CTD PMID:33512557 GCLM Human antirheumatic drug increases expression EXP 6480464 Antirheumatic Agents results in increased expression of GCLM mRNA CTD PMID:24449571 GCLM Human apigenin increases expression ISO Gclm (Rattus norvegicus) 6480464 Apigenin results in increased expression of GCLM mRNA and Apigenin results in increased expression of GCLM protein CTD PMID:22864849 GCLM Human apigenin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Apigenin results in increased expression of GCLM mRNA] which results in decreased susceptibility to tert-Butylhydroperoxide CTD PMID:22864849 GCLM Human arachidonic acid increases expression EXP 6480464 Arachidonic Acid results in increased expression of GCLM mRNA CTD PMID:16704987 GCLM Human arachidonic acid increases expression ISO Gclm (Rattus norvegicus) 6480464 Arachidonic Acid metabolite results in increased expression of GCLM mRNA CTD PMID:27012417 GCLM Human aristolochic acid A decreases expression EXP 6480464 aristolochic acid I results in decreased expression of GCLM mRNA CTD PMID:33212167 GCLM Human arotinoid acid multiple interactions EXP 6480464 [4-(2-(5 more ... CTD PMID:34480604 GCLM Human arsane increases expression EXP 6480464 Arsenic results in increased expression of GCLM mRNA and Arsenic results in increased expression of GCLM protein CTD PMID:18487201 more ... GCLM Human arsane multiple interactions ISO Gclm (Mus musculus) 6480464 NFE2L2 protein affects the reaction [Arsenic results in increased expression of GCLM protein] CTD PMID:35523338 GCLM Human arsane increases expression ISO Gclm (Mus musculus) 6480464 Arsenic results in increased expression of GCLM protein CTD PMID:35523338 GCLM Human arsane multiple interactions EXP 6480464 [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:32188015 more ... GCLM Human arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of GCLM mRNA and Arsenic results in increased expression of GCLM protein CTD PMID:18487201 more ... GCLM Human arsenic atom increases expression ISO Gclm (Mus musculus) 6480464 Arsenic results in increased expression of GCLM protein CTD PMID:35523338 GCLM Human arsenic atom multiple interactions ISO Gclm (Mus musculus) 6480464 NFE2L2 protein affects the reaction [Arsenic results in increased expression of GCLM protein] CTD PMID:35523338 GCLM Human arsenic atom multiple interactions EXP 6480464 [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:32188015 more ... GCLM Human arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of GCLM mRNA CTD PMID:22476201 and PMID:25680285 GCLM Human arsenite(3-) multiple interactions EXP 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of GCLM mRNA more ... CTD PMID:22476201 more ... GCLM Human arsenite(3-) increases expression ISO Gclm (Mus musculus) 6480464 arsenite results in increased expression of GCLM mRNA and arsenite results in increased expression of GCLM protein CTD PMID:15894712 more ... GCLM Human arsenite(3-) increases stability ISO Gclm (Mus musculus) 6480464 arsenite results in increased stability of GCLM mRNA CTD PMID:19328227 GCLM Human arsenite(3-) multiple interactions ISO Gclm (Mus musculus) 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [arsenite results in increased expression of GCLM mRNA] more ... CTD PMID:15894712 more ... GCLM Human arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GCLM mRNA CTD PMID:15725085 more ... GCLM Human arsenous acid multiple interactions EXP 6480464 [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:19350554 more ... GCLM Human arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of GCLM protein CTD PMID:25341331 GCLM Human artesunate decreases response to substance EXP 6480464 GCLM mRNA results in decreased susceptibility to artesunate CTD PMID:15796179 GCLM Human astilbin multiple interactions EXP 6480464 astilbin promotes the reaction [Cisplatin results in increased expression of GCLM mRNA] CTD PMID:29471006 GCLM Human atrazine increases expression ISO Gclm (Mus musculus) 6480464 Atrazine results in increased expression of GCLM mRNA CTD PMID:36216167 GCLM Human atrazine multiple interactions ISO Gclm (Mus musculus) 6480464 Lycopene inhibits the reaction [Atrazine results in increased expression of GCLM mRNA] CTD PMID:36216167 GCLM Human Augmentin increases expression EXP 6480464 Amoxicillin-Potassium Clavulanate Combination results in increased expression of GCLM mRNA CTD PMID:34767876 GCLM Human azathioprine increases expression EXP 6480464 Azathioprine results in increased expression of GCLM mRNA CTD PMID:18222062 more ... GCLM Human azoxystrobin increases expression EXP 6480464 azoxystrobin results in increased expression of GCLM mRNA CTD PMID:33512557 GCLM Human Bandrowski's base increases expression EXP 6480464 Bandrowski's base results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human Bardoxolone methyl increases expression EXP 6480464 bardoxolone methyl results in increased expression of GCLM and bardoxolone methyl results in increased expression of GCLM mRNA CTD PMID:21723306 and PMID:34480604 GCLM Human Bardoxolone methyl decreases expression EXP 6480464 bardoxolone methyl results in decreased expression of GCLM mRNA CTD PMID:35724838 GCLM Human benfotiamine multiple interactions ISO Gclm (Mus musculus) 6480464 NFE2L2 protein affects the reaction [benphothiamine metabolite results in increased expression of GCLM mRNA] and NFE2L2 protein affects the reaction [benphothiamine results in increased expression of GCLM mRNA] CTD PMID:29860433 GCLM Human benfotiamine increases expression ISO Gclm (Mus musculus) 6480464 benphothiamine metabolite results in increased expression of GCLM mRNA and benphothiamine results in increased expression of GCLM mRNA CTD PMID:29860433 GCLM Human benzalkonium chloride increases expression EXP 6480464 Benzalkonium Compounds results in increased expression of GCLM mRNA CTD PMID:30806763 GCLM Human benzene increases expression EXP 6480464 Benzene results in increased expression of GCLM mRNA CTD PMID:21843810 GCLM Human benzidine increases expression EXP 6480464 benzidine results in increased expression of GCLM mRNA CTD PMID:26198647 GCLM Human benzo[a]pyrene multiple interactions ISO Gclm (Mus musculus) 6480464 [arsenite co-treated with Benzo(a)pyrene] results in increased expression of GCLM mRNA more ... CTD PMID:15894712 more ... GCLM Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of GCLM promoter CTD PMID:27901495 GCLM Human benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of GCLM mRNA and Benzo(a)pyrene results in increased expression of GCLM protein CTD PMID:20064835 more ... GCLM Human benzo[a]pyrene increases response to substance ISO Gclm (Mus musculus) 6480464 GCLM gene mutant form results in increased susceptibility to Benzo(a)pyrene CTD PMID:23135907 and PMID:28279692 GCLM Human benzo[a]pyrene decreases response to substance ISO Gclm (Mus musculus) 6480464 GCLM gene mutant form results in decreased susceptibility to Benzo(a)pyrene CTD PMID:24291350 GCLM Human benzo[a]pyrene increases expression ISO Gclm (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of GCLM mRNA CTD PMID:15034205 more ... GCLM Human benzo[a]pyrene affects response to substance ISO Gclm (Mus musculus) 6480464 GCLM protein affects the susceptibility to Benzo(a)pyrene CTD PMID:22253057 GCLM Human benzo[a]pyrene decreases expression ISO Gclm (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of GCLM mRNA CTD PMID:22228805 GCLM Human benzo[a]pyrene diol epoxide I decreases expression EXP 6480464 7 more ... CTD PMID:19150397 GCLM Human benzoic acid increases expression EXP 6480464 Benzoic Acid results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human benzoquinones increases expression ISO Gclm (Mus musculus) 6480464 Benzoquinones analog results in increased expression of GCLM protein CTD PMID:21651925 GCLM Human benzylpenicillin increases expression EXP 6480464 Penicillin G results in increased expression of GCLM mRNA CTD PMID:22609641 GCLM Human berberine multiple interactions ISO Gclm (Rattus norvegicus) 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of GCLM mRNA] CTD PMID:35121005 GCLM Human beta-lapachone increases expression EXP 6480464 beta-lapachone results in increased expression of GCLM mRNA CTD PMID:38218311 GCLM Human beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of GCLM mRNA CTD PMID:19737606 and PMID:32858204 GCLM Human beta-naphthoflavone multiple interactions ISO Gclm (Mus musculus) 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GCLM mRNA CTD PMID:19737545 GCLM Human beta-tocopherol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 GCLM Human Betanin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 6-chloro-2 more ... CTD PMID:33661552 GCLM Human bis(2-ethylhexyl) phthalate increases expression ISO Gclm (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of GCLM mRNA and Diethylhexyl Phthalate results in increased expression of GCLM protein CTD PMID:35818324 and PMID:35917956 GCLM Human bis(2-ethylhexyl) phthalate decreases expression ISO Gclm (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of GCLM mRNA CTD PMID:36696656 GCLM Human bis(2-ethylhexyl) phthalate multiple interactions ISO Gclm (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLM mRNA] CTD PMID:35917956 GCLM Human bisdemethoxycurcumin increases expression ISO Gclm (Mus musculus) 6480464 bisdemethoxycurcumin results in increased expression of GCLM mRNA CTD PMID:17535857 GCLM Human bisdemethoxycurcumin increases expression EXP 6480464 bisdemethoxycurcumin results in increased expression of GCLM mRNA and bisdemethoxycurcumin results in increased expression of GCLM protein CTD PMID:19188863 GCLM Human bisphenol A decreases expression ISO Gclm (Mus musculus) 6480464 bisphenol A results in decreased expression of GCLM mRNA CTD PMID:26063408 GCLM Human bisphenol A increases expression ISO Gclm (Rattus norvegicus) 6480464 bisphenol A results in increased expression of GCLM mRNA CTD PMID:32145629 GCLM Human bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of GCLM mRNA CTD PMID:30903817 GCLM Human bisphenol A increases methylation ISO Gclm (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of GCLM gene CTD PMID:28505145 GCLM Human bisphenol A decreases expression ISO Gclm (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of GCLM mRNA CTD PMID:25181051 more ... GCLM Human Bisphenol A diglycidyl ether increases expression EXP 6480464 2 and 2-bis(4-glycidyloxyphenyl)propane results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human Bisphenol A glycidylmethacrylate increases expression EXP 6480464 Bisphenol A-Glycidyl Methacrylate results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of GCLM protein CTD PMID:34186270 GCLM Human bortezomib increases expression ISO Gclm (Rattus norvegicus) 6480464 Bortezomib results in increased expression of GCLM mRNA CTD PMID:35121005 GCLM Human bortezomib multiple interactions ISO Gclm (Rattus norvegicus) 6480464 Berberine inhibits the reaction [Bortezomib results in increased expression of GCLM mRNA] CTD PMID:35121005 GCLM Human bromobenzene increases expression ISO Gclm (Rattus norvegicus) 6480464 bromobenzene results in increased expression of GCLM mRNA CTD PMID:12628495 GCLM Human buta-1,3-diene increases expression ISO Gclm (Mus musculus) 6480464 1 and 3-butadiene results in increased expression of GCLM mRNA CTD PMID:29038090 GCLM Human butan-1-ol multiple interactions EXP 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GCLM mRNA CTD PMID:29432896 GCLM Human C60 fullerene decreases expression ISO Gclm (Rattus norvegicus) 6480464 fullerene C60 results in decreased expression of GCLM mRNA CTD PMID:19167457 GCLM Human cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of GCLM mRNA CTD PMID:21120746 more ... GCLM Human cadmium atom decreases expression ISO Gclm (Mus musculus) 6480464 Cadmium results in decreased expression of GCLM mRNA CTD PMID:37270049 GCLM Human cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GCLM mRNA CTD PMID:35301059 GCLM Human cadmium atom multiple interactions ISO Gclm (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GCLM mRNA more ... CTD PMID:33398418 GCLM Human cadmium atom increases expression ISO Gclm (Rattus norvegicus) 6480464 Cadmium results in increased expression of GCLM mRNA CTD PMID:25388156 GCLM Human cadmium dichloride increases expression ISO Gclm (Mus musculus) 6480464 Cadmium Chloride results in increased expression of GCLM mRNA CTD PMID:20061341 GCLM Human cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GCLM mRNA more ... CTD PMID:26365678 more ... GCLM Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of GCLM mRNA and Cadmium Chloride results in increased expression of GCLM protein CTD PMID:25596134 more ... GCLM Human cadmium dichloride multiple interactions ISO Gclm (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GCLM mRNA more ... CTD PMID:26827822 and PMID:33398418 GCLM Human cadmium dichloride increases expression ISO Gclm (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of GCLM mRNA CTD PMID:19010381 GCLM Human cannabidiol increases expression ISO Gclm (Mus musculus) 6480464 Cannabidiol results in increased expression of GCLM mRNA CTD PMID:21542829 GCLM Human cannabidiol increases expression EXP 6480464 Cannabidiol results in increased expression of GCLM mRNA CTD PMID:31518892 GCLM Human captan increases expression ISO Gclm (Mus musculus) 6480464 Captan results in increased expression of GCLM mRNA CTD PMID:31558096 GCLM Human carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of GCLM mRNA CTD PMID:24752500 and PMID:25979313 GCLM Human carbaryl increases expression EXP 6480464 Carbaryl results in increased expression of GCLM mRNA CTD PMID:27829164 GCLM Human carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon results in increased expression of GCLM protein CTD PMID:23026733 GCLM Human carnosic acid multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GCLM protein] more ... CTD PMID:25446857 more ... GCLM Human carnosic acid multiple interactions ISO Gclm (Rattus norvegicus) 6480464 salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLM protein] CTD PMID:25446857 GCLM Human carnosic acid increases expression EXP 6480464 salvin results in increased expression of GCLM protein CTD PMID:26577515 and PMID:26686574 GCLM Human Carnosol increases expression EXP 6480464 carnosol results in increased expression of GCLM mRNA CTD PMID:20116392 GCLM Human celastrol increases expression EXP 6480464 celastrol results in increased expression of GCLM mRNA CTD PMID:17010675 GCLM Human celastrol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 celastrol inhibits the reaction [Doxorubicin results in decreased expression of GCLM mRNA] CTD PMID:30588110 GCLM Human ceric oxide decreases expression ISO Gclm (Rattus norvegicus) 6480464 ceric oxide results in decreased expression of GCLM mRNA CTD PMID:29463257 GCLM Human cerium trichloride decreases expression EXP 6480464 cerous chloride results in decreased expression of GCLM mRNA CTD PMID:28954213 GCLM Human chalcone increases expression EXP 6480464 Chalcone analog results in increased expression of GCLM mRNA and Chalcone analog results in increased expression of GCLM protein CTD PMID:31299238 GCLM Human chenodeoxycholic acid multiple interactions EXP 6480464 [Chenodeoxycholic Acid results in increased expression of GCLM protein] which results in increased abundance of Glutathione more ... CTD PMID:17724089 and PMID:33819548 GCLM Human chenodeoxycholic acid increases expression EXP 6480464 Chenodeoxycholic Acid results in increased expression of GCLM protein CTD PMID:17724089 GCLM Human CHIR 99021 multiple interactions EXP 6480464 [4-(2-(5 more ... CTD PMID:34480604 GCLM Human chlorambucil multiple interactions EXP 6480464 [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Chlorambucil CTD PMID:10900222 GCLM Human chloroacetaldehyde increases expression EXP 6480464 chloroacetaldehyde results in increased expression of GCLM mRNA CTD PMID:25596134 GCLM Human chlorogenic acid increases expression EXP 6480464 Chlorogenic Acid results in increased expression of GCLM mRNA CTD PMID:29136249 GCLM Human chloropicrin increases expression EXP 6480464 chloropicrin results in increased expression of GCLM mRNA CTD PMID:24211530 GCLM Human chloroprene increases expression ISO Gclm (Mus musculus) 6480464 Chloroprene results in increased expression of GCLM mRNA CTD PMID:23125180 GCLM Human chlorpyrifos decreases expression ISO Gclm (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of GCLM mRNA CTD PMID:32955216 GCLM Human chlorpyrifos multiple interactions ISO Gclm (Mus musculus) 6480464 Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLM mRNA] CTD PMID:32955216 GCLM Human choline multiple interactions ISO Gclm (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of GCLM mRNA CTD PMID:20938992 GCLM Human chromium(6+) multiple interactions ISO Gclm (Mus musculus) 6480464 [chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of GCLM mRNA CTD PMID:25820237 GCLM Human chrysin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Buthionine Sulfoximine results in decreased activity of [GCLC protein binds to GCLM protein]] inhibits the reaction [chrysin inhibits the reaction [tert-Butylhydroperoxide results in increased chemical synthesis of Reactive Oxygen Species]] more ... CTD PMID:22864849 and PMID:33121995 GCLM Human chrysin increases expression ISO Gclm (Rattus norvegicus) 6480464 chrysin results in increased expression of GCLM mRNA and chrysin results in increased expression of GCLM protein CTD PMID:22864849 GCLM Human cidofovir anhydrous increases expression EXP 6480464 Cidofovir results in increased expression of GCLM mRNA CTD PMID:25596134 GCLM Human cinnamyl alcohol increases expression EXP 6480464 cinnamyl alcohol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... GCLM Human cisplatin multiple interactions EXP 6480464 astilbin promotes the reaction [Cisplatin results in increased expression of GCLM mRNA] more ... CTD PMID:17628013 more ... GCLM Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of GCLM mRNA CTD PMID:25450742 more ... GCLM Human cisplatin decreases expression ISO Gclm (Rattus norvegicus) 6480464 Cisplatin results in decreased expression of GCLM mRNA CTD PMID:33661552 GCLM Human cisplatin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 6-chloro-2 more ... CTD PMID:33661552 GCLM Human citraconic acid increases expression ISO Gclm (Mus musculus) 6480464 citraconic acid results in increased expression of GCLM mRNA CTD PMID:27277809 GCLM Human citraconic acid increases expression ISO Gclm (Rattus norvegicus) 6480464 citraconic acid results in increased expression of GCLM protein CTD PMID:27277809 GCLM Human citral increases expression EXP 6480464 citral results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human clavulanic acid increases expression EXP 6480464 Clavulanic Acid results in increased expression of GCLM mRNA CTD PMID:34767876 GCLM Human Clivoline decreases expression EXP 6480464 clivorine results in decreased expression of GCLM mRNA CTD PMID:25881548 GCLM Human Clivoline multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Quercetin inhibits the reaction [clivorine results in decreased expression of GCLM mRNA]] and Quercetin inhibits the reaction [clivorine results in decreased expression of GCLM mRNA] CTD PMID:25881548 GCLM Human clodronic acid increases expression EXP 6480464 Clodronic Acid results in increased expression of GCLM mRNA CTD PMID:25596134 GCLM Human clofibrate decreases expression ISO Gclm (Rattus norvegicus) 6480464 Clofibrate results in decreased expression of GCLM protein CTD PMID:16470657 GCLM Human cobalt atom multiple interactions EXP 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of GCLM mRNA CTD PMID:23052192 GCLM Human cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of GCLM mRNA CTD PMID:19320972 more ... GCLM Human cobalt dichloride multiple interactions EXP 6480464 KEAP1 protein inhibits the reaction [cobaltous chloride results in increased expression of GCLM mRNA] and NFE2L2 protein promotes the reaction [cobaltous chloride results in increased expression of GCLM mRNA] CTD PMID:29966676 GCLM Human cobalt dichloride increases expression ISO Gclm (Rattus norvegicus) 6480464 cobaltous chloride results in increased expression of GCLM mRNA and cobaltous chloride results in increased expression of GCLM protein CTD PMID:24386269 GCLM Human cocaine affects expression ISO Gclm (Rattus norvegicus) 6480464 Cocaine affects the expression of GCLM mRNA CTD PMID:20187946 GCLM Human cocaine multiple interactions ISO Gclm (Mus musculus) 6480464 PRKCD protein affects the reaction [Cocaine results in increased expression of GCLM mRNA] and rottlerin promotes the reaction [Cocaine results in increased expression of GCLM mRNA] CTD PMID:30393195 GCLM Human cocaine increases expression ISO Gclm (Mus musculus) 6480464 Cocaine results in increased expression of GCLM mRNA CTD PMID:30393195 GCLM Human coniferyl aldehyde increases expression EXP 6480464 coniferaldehyde results in increased expression of GCLM mRNA CTD PMID:26275128 GCLM Human copper atom increases expression ISO Gclm (Mus musculus) 6480464 Copper analog results in increased expression of GCLM protein and Copper results in increased expression of GCLM protein CTD PMID:23882024 GCLM Human copper atom multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of GCLM mRNA more ... CTD PMID:20971185 more ... GCLM Human copper(0) increases expression ISO Gclm (Mus musculus) 6480464 Copper analog results in increased expression of GCLM protein and Copper results in increased expression of GCLM protein CTD PMID:23882024 GCLM Human copper(0) multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of GCLM mRNA more ... CTD PMID:20971185 more ... GCLM Human copper(II) chloride increases expression EXP 6480464 cupric chloride results in increased expression of GCLM mRNA CTD PMID:17211630 more ... GCLM Human copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of GCLM mRNA CTD PMID:19549813 GCLM Human cortisol multiple interactions EXP 6480464 [4-(2-(5 more ... CTD PMID:34480604 GCLM Human coumarin increases expression ISO Gclm (Rattus norvegicus) 6480464 coumarin results in increased expression of GCLM mRNA CTD PMID:18480146 GCLM Human coumestrol multiple interactions EXP 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of GCLM mRNA CTD PMID:19167446 GCLM Human crocidolite asbestos multiple interactions ISO Gclm (Mus musculus) 6480464 [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos more ... CTD PMID:15520183 GCLM Human crocidolite asbestos increases expression ISO Gclm (Mus musculus) 6480464 Asbestos and Crocidolite results in increased expression of GCLM mRNA CTD PMID:15520183 GCLM Human CU-O LINKAGE increases expression ISO Gclm (Mus musculus) 6480464 cupric oxide analog results in increased expression of GCLM protein CTD PMID:23882024 GCLM Human CU-O LINKAGE increases expression EXP 6480464 cupric oxide results in increased expression of GCLM mRNA CTD PMID:24343273 GCLM Human cumene hydroperoxide increases expression ISO Gclm (Mus musculus) 6480464 cumene hydroperoxide results in increased expression of GCLM mRNA CTD PMID:30547568 GCLM Human curcumin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 Curcumin results in increased activity of [GCLC protein binds to GCLM protein] CTD PMID:17602960 GCLM Human curcumin multiple interactions ISO Gclm (Mus musculus) 6480464 Curcumin promotes the reaction [sodium arsenite results in increased expression of GCLM mRNA] CTD PMID:34272803 GCLM Human curcumin increases expression EXP 6480464 Curcumin analog results in increased expression of GCLM mRNA more ... CTD PMID:17198877 more ... GCLM Human curcumin multiple interactions EXP 6480464 NFE2L2 mutant form inhibits the reaction [Curcumin analog results in increased expression of GCLM mRNA] and NFE2L2 mutant form inhibits the reaction [Curcumin results in increased expression of GCLM mRNA] CTD PMID:23954767 GCLM Human curcumin increases expression ISO Gclm (Mus musculus) 6480464 Curcumin results in increased expression of GCLM mRNA CTD PMID:17535857 more ... GCLM Human curcumin increases expression ISO Gclm (Rattus norvegicus) 6480464 Curcumin results in increased expression of GCLM mRNA and Curcumin results in increased expression of GCLM protein CTD PMID:17602960 and PMID:18332871 GCLM Human cycloheximide multiple interactions ISO Gclm (Mus musculus) 6480464 Cycloheximide inhibits the reaction [arsenite results in increased activity of [GCLC protein binds to GCLM protein]] more ... CTD PMID:19328227 GCLM Human cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of GCLM mRNA CTD PMID:20106945 more ... GCLM Human cyclosporin A decreases expression ISO Gclm (Rattus norvegicus) 6480464 Cyclosporine results in decreased expression of GCLM mRNA CTD PMID:11589784 and PMID:25596134 GCLM Human D-glucose multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Glucose co-treated with gastrodin] affects the expression of GCLM mRNA CTD PMID:33764184 GCLM Human D-glucose multiple interactions ISO Gclm (Mus musculus) 6480464 [Glucose co-treated with gastrodin] affects the expression of GCLM mRNA CTD PMID:33764184 GCLM Human DDT increases expression EXP 6480464 DDT results in increased expression of GCLM mRNA CTD PMID:26198647 GCLM Human deguelin increases expression EXP 6480464 deguelin results in increased expression of GCLM mRNA CTD PMID:33512557 GCLM Human delta-tocopherol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 GCLM Human demethoxycurcumin increases expression ISO Gclm (Mus musculus) 6480464 demethoxycurcumin results in increased expression of GCLM mRNA CTD PMID:17535857 GCLM Human demethoxycurcumin increases expression EXP 6480464 demethoxycurcumin results in increased expression of GCLM mRNA and demethoxycurcumin results in increased expression of GCLM protein CTD PMID:19188863 and PMID:23386263 GCLM Human deoxycholic acid multiple interactions EXP 6480464 [Deoxycholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA more ... CTD PMID:17724089 and PMID:33819548 GCLM Human deoxynivalenol increases expression ISO Gclm (Mus musculus) 6480464 deoxynivalenol results in increased expression of GCLM mRNA CTD PMID:34400200 GCLM Human dexamethasone multiple interactions ISO Gclm (Mus musculus) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of GCLM mRNA CTD PMID:33412187 GCLM Human dextran sulfate multiple interactions ISO Gclm (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GCLM mRNA CTD PMID:29950665 GCLM Human dextromethorphan affects expression ISO Gclm (Mus musculus) 6480464 Dextromethorphan affects the expression of GCLM mRNA CTD PMID:34740715 GCLM Human dextromethorphan multiple interactions ISO Gclm (Mus musculus) 6480464 PRKCD protein affects the reaction [Dextromethorphan affects the expression of GCLM mRNA] more ... CTD PMID:34740715 GCLM Human diallyl disulfide multiple interactions ISO Gclm (Mus musculus) 6480464 diallyl disulfide promotes the reaction [lipopolysaccharide more ... CTD PMID:34896185 GCLM Human diallyl disulfide increases expression EXP 6480464 diallyl disulfide results in increased expression of GCLM mRNA CTD PMID:34887701 GCLM Human diallyl disulfide increases expression ISO Gclm (Mus musculus) 6480464 diallyl disulfide results in increased expression of GCLM mRNA CTD PMID:34896185 GCLM Human diallyl trisulfide increases expression EXP 6480464 diallyl trisulfide results in increased expression of GCLM mRNA CTD PMID:34887701 GCLM Human Diallyltetrasulfane increases expression EXP 6480464 diallyl tetrasulfide results in increased expression of GCLM mRNA CTD PMID:34887701 GCLM Human diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of GCLM protein CTD PMID:25341331 GCLM Human diarsenic trioxide multiple interactions EXP 6480464 [Arsenic Trioxide results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:19350554 more ... GCLM Human diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GCLM mRNA CTD PMID:15725085 more ... GCLM Human diazinon increases expression EXP 6480464 Diazinon results in increased expression of GCLM mRNA CTD PMID:26198647 GCLM Human Dibutyl phosphate affects expression EXP 6480464 di-n-butylphosphoric acid affects the expression of GCLM mRNA CTD PMID:37042841 GCLM Human dibutyl phthalate increases expression ISO Gclm (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of GCLM mRNA CTD PMID:21266533 GCLM Human dichlorine multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Ozone co-treated with Chlorine] results in decreased expression of GCLM mRNA CTD PMID:18636392 GCLM Human diclofenac affects expression EXP 6480464 Diclofenac affects the expression of GCLM mRNA CTD PMID:24752500 GCLM Human diethyl malate multiple interactions ISO Gclm (Mus musculus) 6480464 S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GCLM mRNA] CTD PMID:24814887 GCLM Human diethyl malate affects expression ISO Gclm (Mus musculus) 6480464 diethyl malate affects the expression of GCLM mRNA CTD PMID:24814887 GCLM Human diethyl maleate increases expression ISO Gclm (Rattus norvegicus) 6480464 diethyl maleate results in increased expression of GCLM mRNA and diethyl maleate results in increased expression of GCLM protein CTD PMID:10978506 more ... GCLM Human diethyl maleate increases expression EXP 6480464 diethyl maleate results in increased expression of GCLM mRNA CTD PMID:33545341 and PMID:34480604 GCLM Human diethyl maleate increases expression ISO Gclm (Mus musculus) 6480464 diethyl maleate results in increased expression of GCLM mRNA CTD PMID:25270620 GCLM Human dihydrogen multiple interactions ISO Gclm (Mus musculus) 6480464 Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLM mRNA] CTD PMID:32955216 GCLM Human dimethyl fumarate multiple interactions ISO Gclm (Mus musculus) 6480464 NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLM mRNA] CTD PMID:27277809 GCLM Human dimethyl fumarate increases expression ISO Gclm (Mus musculus) 6480464 Dimethyl Fumarate results in increased expression of GCLM mRNA CTD PMID:27277809 GCLM Human dimethyl fumarate increases expression ISO Gclm (Rattus norvegicus) 6480464 Dimethyl Fumarate results in increased expression of GCLM protein CTD PMID:27277809 GCLM Human dimethylarsinic acid multiple interactions EXP 6480464 [Cacodylic Acid results in increased abundance of Arsenic] which results in increased expression of GCLM protein CTD PMID:33434570 GCLM Human dinoseb increases expression ISO Gclm (Mus musculus) 6480464 dinoseb results in increased expression of GCLM mRNA CTD PMID:30547568 GCLM Human dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of GCLM mRNA CTD PMID:25596134 more ... GCLM Human dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of GCLM mRNA CTD PMID:29966676 GCLM Human dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression EXP 6480464 Antimony Potassium Tartrate results in increased expression of GCLM mRNA CTD PMID:28713220 GCLM Human dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions EXP 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GCLM mRNA CTD PMID:32076005 GCLM Human diprotium multiple interactions ISO Gclm (Mus musculus) 6480464 Hydrogen inhibits the reaction [Chlorpyrifos results in decreased expression of GCLM mRNA] CTD PMID:32955216 GCLM Human diquat increases expression EXP 6480464 Diquat results in increased expression of GCLM mRNA and Diquat results in increased expression of GCLM protein CTD PMID:21172416 and PMID:38128689 GCLM Human diquat increases expression ISO Gclm (Mus musculus) 6480464 Diquat results in increased expression of GCLM mRNA CTD PMID:16962985 and PMID:20826540 GCLM Human disulfiram increases expression EXP 6480464 Disulfiram results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human dodecan-1-ol increases expression EXP 6480464 Dodecanol analog results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human domoic acid decreases response to substance ISO Gclm (Mus musculus) 6480464 [GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to 2 more ... CTD PMID:19200344 and PMID:23315585 GCLM Human domoic acid affects response to substance ISO Gclm (Mus musculus) 6480464 GCLM affects the susceptibility to domoic acid CTD PMID:17804861 GCLM Human domoic acid increases expression ISO Gclm (Mus musculus) 6480464 domoic acid results in increased expression of GCLM mRNA and domoic acid results in increased expression of GCLM protein CTD PMID:23315585 GCLM Human dopamine multiple interactions ISO Gclm (Mus musculus) 6480464 [GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased abundance of Dopamine CTD PMID:23704229 GCLM Human dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 GCLM Human dorsomorphin multiple interactions ISO Gclm (Mus musculus) 6480464 [Acetaminophen co-treated with amlexanox co-treated with dorsomorphin] affects the expression of GCLM mRNA CTD PMID:31697998 GCLM Human doxorubicin multiple interactions EXP 6480464 [GCLC protein co-treated with GCLM protein] promotes the reaction [GSTP1 protein results in decreased susceptibility to Doxorubicin] CTD PMID:10900222 GCLM Human doxorubicin decreases expression ISO Gclm (Mus musculus) 6480464 Doxorubicin results in decreased expression of GCLM mRNA CTD PMID:37499777 GCLM Human doxorubicin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 celastrol inhibits the reaction [Doxorubicin results in decreased expression of GCLM mRNA] more ... CTD PMID:30588110 and PMID:37499777 GCLM Human doxorubicin decreases expression ISO Gclm (Rattus norvegicus) 6480464 Doxorubicin results in decreased expression of GCLM mRNA CTD PMID:30588110 and PMID:37499777 GCLM Human doxorubicin increases metabolic processing ISO Gclm (Mus musculus) 6480464 GCLM gene mutant form results in increased metabolism of Doxorubicin CTD PMID:25446851 GCLM Human doxorubicin multiple interactions ISO Gclm (Mus musculus) 6480464 [GCLM gene mutant form results in increased metabolism of Doxorubicin] which results in increased abundance of adriamycinol more ... CTD PMID:25446851 more ... GCLM Human doxorubicin increases expression ISO Gclm (Mus musculus) 6480464 Doxorubicin results in increased expression of GCLM protein CTD PMID:26822305 GCLM Human elesclomol multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [elesclomol results in increased expression of GCLM mRNA] CTD PMID:18723479 GCLM Human elesclomol increases expression EXP 6480464 elesclomol results in increased expression of GCLM mRNA CTD PMID:18723479 GCLM Human emodin increases expression ISO Gclm (Rattus norvegicus) 6480464 Emodin results in increased expression of GCLM mRNA CTD PMID:34971761 GCLM Human endosulfan increases expression ISO Gclm (Rattus norvegicus) 6480464 Endosulfan results in increased expression of GCLM mRNA CTD PMID:29391264 GCLM Human entinostat multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 GCLM Human entinostat increases expression EXP 6480464 entinostat results in increased expression of GCLM mRNA CTD PMID:26272509 GCLM Human enzyme inhibitor multiple interactions EXP 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of GCLM protein CTD PMID:23301498 GCLM Human epichlorohydrin increases expression EXP 6480464 Epichlorohydrin results in increased expression of GCLM mRNA CTD PMID:24211530 GCLM Human Epomediol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Ethinyl Estradiol co-treated with epomediol] results in increased activity of GCLM protein CTD PMID:12071332 GCLM Human erastin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 NFE2L2 protein promotes the reaction [erastin results in increased expression of GCLM protein] CTD PMID:32937103 GCLM Human erastin increases expression ISO Gclm (Rattus norvegicus) 6480464 erastin results in increased expression of GCLM protein CTD PMID:32937103 GCLM Human erdosteine increases expression ISO Gclm (Mus musculus) 6480464 erdosteine results in increased expression of GCLM protein CTD PMID:26193055 GCLM Human etacrynic acid multiple interactions EXP 6480464 [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Ethacrynic Acid CTD PMID:10900222 GCLM Human ethanol affects splicing ISO Gclm (Mus musculus) 6480464 Ethanol affects the splicing of GCLM mRNA CTD PMID:30319688 GCLM Human ethionamide multiple interactions EXP 6480464 Ethionamide inhibits the reaction [arsenic trioxide results in increased expression of GCLM mRNA] CTD PMID:26708503 GCLM Human ethylene glycol dimethacrylate increases expression EXP 6480464 ethylene dimethacrylate results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human etoposide multiple interactions EXP 6480464 [GCLC protein co-treated with GCLM protein] promotes the reaction [ABCC1 protein results in decreased susceptibility to Etoposide] and [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Etoposide CTD PMID:10900222 GCLM Human eugenol increases expression EXP 6480464 Eugenol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... GCLM Human fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of GCLM mRNA CTD PMID:25596134 GCLM Human fenpyroximate increases expression EXP 6480464 fenpyroximate results in increased expression of GCLM mRNA CTD PMID:33512557 GCLM Human fluprostenol multiple interactions EXP 6480464 AL 8810 inhibits the reaction [fluprostenol promotes the reaction [Oxidopamine results in increased expression of GCLM mRNA]] more ... CTD PMID:33486071 GCLM Human flutamide increases expression ISO Gclm (Rattus norvegicus) 6480464 Flutamide results in increased expression of GCLM mRNA CTD PMID:24136188 GCLM Human folic acid multiple interactions ISO Gclm (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of GCLM mRNA CTD PMID:20938992 GCLM Human folpet increases expression ISO Gclm (Mus musculus) 6480464 folpet results in increased expression of GCLM mRNA CTD PMID:31558096 GCLM Human formaldehyde decreases expression EXP 6480464 Formaldehyde results in decreased expression of GCLM mRNA CTD PMID:23649840 GCLM Human formononetin multiple interactions EXP 6480464 [formononetin co-treated with Hydrogen Peroxide] results in increased expression of GCLM protein more ... CTD PMID:34077701 GCLM Human fumonisin B1 decreases expression ISO Gclm (Mus musculus) 6480464 fumonisin B1 results in decreased expression of GCLM mRNA CTD PMID:35697133 GCLM Human furosemide multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in decreased expression of GCLM mRNA and [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of GCLM mRNA CTD PMID:29860548 GCLM Human gamma-hexachlorocyclohexane increases expression EXP 6480464 Hexachlorocyclohexane results in increased expression of GCLM mRNA CTD PMID:26198647 GCLM Human gamma-tocopherol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GCLM mRNA] CTD PMID:22389237 GCLM Human Gastrodin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Glucose co-treated with gastrodin] affects the expression of GCLM mRNA CTD PMID:33764184 GCLM Human Gastrodin multiple interactions ISO Gclm (Mus musculus) 6480464 [Glucose co-treated with gastrodin] affects the expression of GCLM mRNA CTD PMID:33764184 GCLM Human gedunin increases expression EXP 6480464 gedunin results in increased expression of GCLM mRNA CTD PMID:17010675 GCLM Human genistein decreases expression ISO Gclm (Rattus norvegicus) 6480464 Genistein results in decreased expression of GCLM mRNA CTD PMID:12075121 GCLM Human gentamycin increases expression ISO Gclm (Rattus norvegicus) 6480464 Gentamicins results in increased expression of GCLM mRNA CTD PMID:33387578 GCLM Human geranial increases expression EXP 6480464 citral results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human Ginkgolide C multiple interactions ISO Gclm (Rattus norvegicus) 6480464 ginkgolide C inhibits the reaction [Paraquat results in decreased expression of GCLM protein] CTD PMID:35707280 GCLM Human ginsenoside Rg1 multiple interactions ISO Gclm (Mus musculus) 6480464 ginsenoside Rg1 inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM protein] CTD PMID:29964319 GCLM Human ginsenoside Rg1 increases expression ISO Gclm (Mus musculus) 6480464 ginsenoside Rg1 results in increased expression of GCLM protein CTD PMID:29964319 GCLM Human glafenine decreases expression ISO Gclm (Rattus norvegicus) 6480464 Glafenine results in decreased expression of GCLM mRNA CTD PMID:24136188 GCLM Human glucose multiple interactions ISO Gclm (Mus musculus) 6480464 [Glucose co-treated with gastrodin] affects the expression of GCLM mRNA CTD PMID:33764184 GCLM Human glucose multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Glucose co-treated with gastrodin] affects the expression of GCLM mRNA CTD PMID:33764184 GCLM Human glutathione multiple interactions EXP 6480464 [Chenodeoxycholic Acid results in increased expression of GCLM protein] which results in increased abundance of Glutathione more ... CTD PMID:12975258 and PMID:17724089 GCLM Human glutathione increases chemical synthesis ISO Gclm (Mus musculus) 6480464 GCLM protein results in increased chemical synthesis of Glutathione CTD PMID:22253057 and PMID:23135907 GCLM Human glutathione increases abundance EXP 6480464 GCLM gene SNP results in increased abundance of Glutathione CTD PMID:32715377 GCLM Human glutathione affects response to substance ISO Gclm (Mus musculus) 6480464 GCLM protein affects the susceptibility to Glutathione CTD PMID:17584759 GCLM Human glutathione decreases abundance ISO Gclm (Mus musculus) 6480464 GCLM gene mutant form results in decreased abundance of Glutathione and GCLM protein mutant form results in decreased abundance of Glutathione CTD PMID:20417186 more ... GCLM Human glutathione increases expression ISO Gclm (Rattus norvegicus) 6480464 Glutathione deficiency results in increased expression of GCLM mRNA CTD PMID:15345336 and PMID:20621112 GCLM Human glutathione affects metabolic processing ISO Gclm (Mus musculus) 6480464 GCLM protein affects the metabolism of Glutathione CTD PMID:22253057 GCLM Human glutathione multiple interactions ISO Gclm (Mus musculus) 6480464 [GCLM gene mutant form results in decreased abundance of Glutathione] which results in decreased susceptibility to Benzo(a)pyrene more ... CTD PMID:20159942 more ... GCLM Human Glutathione ethyl ester multiple interactions ISO Gclm (Mus musculus) 6480464 S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GCLM mRNA] CTD PMID:24814887 GCLM Human glycochenodeoxycholic acid multiple interactions EXP 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of GCLM mRNA more ... CTD PMID:33819548 GCLM Human glycocholic acid multiple interactions EXP 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of GCLM mRNA more ... CTD PMID:33819548 GCLM Human glycodeoxycholic acid multiple interactions EXP 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of GCLM mRNA more ... CTD PMID:33819548 GCLM Human glyoxal increases expression EXP 6480464 Glyoxal results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human glyphosate decreases expression ISO Gclm (Mus musculus) 6480464 Glyphosate results in decreased expression of GCLM protein CTD PMID:37208198 GCLM Human guggulsterone increases expression EXP 6480464 pregna-4 more ... CTD PMID:22851183 GCLM Human guggulsterone increases expression ISO Gclm (Mus musculus) 6480464 pregna-4 more ... CTD PMID:22851183 GCLM Human GW 4064 increases expression ISO Gclm (Mus musculus) 6480464 GW 4064 results in increased expression of GCLM mRNA CTD PMID:26655953 GCLM Human hemin multiple interactions EXP 6480464 [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM mRNA and [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM protein CTD PMID:33434570 GCLM Human hemin increases expression EXP 6480464 Hemin results in increased expression of GCLM mRNA and Hemin results in increased expression of GCLM protein CTD PMID:33434570 GCLM Human hexachlorobenzene increases expression ISO Gclm (Rattus norvegicus) 6480464 Hexachlorobenzene results in increased expression of GCLM mRNA CTD PMID:15159207 GCLM Human hexadecanoic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein and Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein] CTD PMID:36905866 GCLM Human hexamethylene diisocyanate increases expression EXP 6480464 1 and 6-hexamethylene diisocyanate results in increased expression of GCLM mRNA CTD PMID:24211530 GCLM Human hexane increases expression EXP 6480464 n-hexane results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human homoeriodictyol increases expression EXP 6480464 homoeriodictyol results in increased expression of GCLM mRNA CTD PMID:29902531 GCLM Human hydrogen chloride multiple interactions ISO Gclm (Mus musculus) 6480464 NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GCLM mRNA] CTD PMID:29618784 GCLM Human hydrogen chloride increases expression ISO Gclm (Mus musculus) 6480464 Hydrochloric Acid results in increased expression of GCLM mRNA CTD PMID:29618784 GCLM Human hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of GCLM mRNA CTD PMID:18951874 and PMID:29274434 GCLM Human hydrogen peroxide multiple interactions EXP 6480464 [formononetin co-treated with Hydrogen Peroxide] results in increased expression of GCLM protein more ... CTD PMID:29274434 more ... GCLM Human hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of GCLM mRNA and Hydrogen Peroxide results in increased expression of GCLM protein CTD PMID:12414654 more ... GCLM Human hydrogen peroxide decreases response to substance ISO Gclm (Mus musculus) 6480464 [GCLM protein results in decreased susceptibility to domoic acid] which results in decreased susceptibility to Hydrogen Peroxide CTD PMID:23315585 GCLM Human hydroquinone increases expression EXP 6480464 hydroquinone results in increased expression of GCLM mRNA and hydroquinone results in increased expression of GCLM protein CTD PMID:21059386 and PMID:31256213 GCLM Human hydroquinone increases expression ISO Gclm (Mus musculus) 6480464 hydroquinone results in increased expression of GCLM mRNA and hydroquinone results in increased expression of GCLM protein CTD PMID:30547568 GCLM Human hypochlorous acid increases expression EXP 6480464 Hypochlorous Acid results in increased expression of GCLM mRNA CTD PMID:18156441 GCLM Human hypochlorous acid increases expression ISO Gclm (Mus musculus) 6480464 Hypochlorous Acid results in increased expression of GCLM mRNA CTD PMID:19376150 GCLM Human ibuprofen increases expression EXP 6480464 Ibuprofen results in increased expression of GCLM mRNA CTD PMID:11909699 and PMID:25596134 GCLM Human ifosfamide increases expression EXP 6480464 Ifosfamide results in increased expression of GCLM mRNA CTD PMID:25596134 GCLM Human indometacin increases expression EXP 6480464 Indomethacin results in increased expression of GCLM mRNA CTD PMID:11909699 GCLM Human indometacin multiple interactions ISO Gclm (Mus musculus) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of GCLM mRNA CTD PMID:33412187 GCLM Human iodixanol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in decreased expression of GCLM mRNA CTD PMID:29860548 GCLM Human iohexol multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of GCLM mRNA CTD PMID:29860548 GCLM Human iron atom multiple interactions EXP 6480464 Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GCLM mRNA] CTD PMID:19073151 GCLM Human iron atom decreases expression EXP 6480464 Iron results in decreased expression of GCLM mRNA CTD PMID:19073151 GCLM Human iron(0) multiple interactions EXP 6480464 Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GCLM mRNA] CTD PMID:19073151 GCLM Human iron(0) decreases expression EXP 6480464 Iron results in decreased expression of GCLM mRNA CTD PMID:19073151 GCLM Human iron(III) citrate increases expression EXP 6480464 ferric citrate results in increased expression of GCLM mRNA CTD PMID:29959986 GCLM Human isoeugenol increases expression EXP 6480464 isoeugenol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... GCLM Human isoflavones increases expression EXP 6480464 Isoflavones results in increased expression of GCLM mRNA CTD PMID:17374662 GCLM Human isoniazide increases expression ISO Gclm (Mus musculus) 6480464 Isoniazid results in increased expression of GCLM mRNA CTD PMID:33771660 GCLM Human isoniazide increases expression ISO Gclm (Rattus norvegicus) 6480464 Isoniazid results in increased expression of GCLM mRNA CTD PMID:33121995 GCLM Human isoniazide multiple interactions ISO Gclm (Rattus norvegicus) 6480464 chrysin inhibits the reaction [Isoniazid results in increased expression of GCLM mRNA] CTD PMID:33121995 GCLM Human isoniazide decreases expression EXP 6480464 Isoniazid results in decreased expression of GCLM mRNA CTD PMID:30008028 GCLM Human isoprenaline increases expression ISO Gclm (Mus musculus) 6480464 Isoproterenol results in increased expression of GCLM mRNA CTD PMID:20003209 GCLM Human isoprenaline multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of GCLM mRNA CTD PMID:30303030 GCLM Human isoprenaline decreases expression ISO Gclm (Mus musculus) 6480464 Isoproterenol results in decreased expression of GCLM mRNA CTD PMID:21335049 GCLM Human isotretinoin decreases expression EXP 6480464 Isotretinoin results in decreased expression of GCLM mRNA CTD PMID:20436886 GCLM Human ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of GCLM protein CTD PMID:32959892 GCLM Human ketoprofen increases expression EXP 6480464 Ketoprofen results in increased expression of GCLM mRNA CTD PMID:11909699 GCLM Human L-ascorbic acid multiple interactions EXP 6480464 [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA CTD PMID:34480604 GCLM Human L-ascorbic acid 2-phosphate multiple interactions EXP 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA CTD PMID:34480604 GCLM Human L-methionine multiple interactions ISO Gclm (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of GCLM mRNA CTD PMID:20938992 GCLM Human lead diacetate increases expression ISO Gclm (Mus musculus) 6480464 lead acetate results in increased expression of GCLM mRNA CTD PMID:25270620 GCLM Human lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of GCLM mRNA CTD PMID:26498409 and PMID:38568856 GCLM Human lead diacetate multiple interactions EXP 6480464 NFE2L2 mutant form inhibits the reaction [lead acetate results in increased expression of GCLM mRNA] CTD PMID:26498409 GCLM Human lead(0) affects abundance EXP 6480464 GCLM gene polymorphism affects the abundance of Lead CTD PMID:25728017 GCLM Human lead(0) increases expression EXP 6480464 Lead results in increased expression of GCLM mRNA CTD PMID:37386098 GCLM Human lead(II) chloride increases expression EXP 6480464 lead chloride results in increased expression of GCLM mRNA CTD PMID:38447685 GCLM Human limonene increases expression EXP 6480464 limonene results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human linoleic acid increases expression EXP 6480464 Linoleic Acid metabolite results in increased expression of GCLM mRNA CTD PMID:26879219 GCLM Human lipoic acid increases expression EXP 6480464 Thioctic Acid results in increased expression of GCLM mRNA and Thioctic Acid results in increased expression of GCLM protein CTD PMID:16249512 and PMID:26365678 GCLM Human lipoic acid multiple interactions EXP 6480464 Thioctic Acid promotes the reaction [Cadmium Chloride results in increased expression of GCLM mRNA] and Thioctic Acid promotes the reaction [Cadmium Chloride results in increased expression of GCLM protein] CTD PMID:26365678 GCLM Human lipoic acid multiple interactions ISO Gclm (Rattus norvegicus) 6480464 Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM mRNA] and Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM protein] CTD PMID:32061141 GCLM Human lipopolysaccharide affects expression ISO Gclm (Mus musculus) 6480464 Lipopolysaccharides affects the expression of GCLM mRNA CTD PMID:22169119 GCLM Human lipopolysaccharide multiple interactions EXP 6480464 [S-(1 more ... CTD PMID:35811015 GCLM Human lipopolysaccharide increases expression ISO Gclm (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of GCLM mRNA CTD PMID:19339665 GCLM Human lipopolysaccharide multiple interactions ISO Gclm (Mus musculus) 6480464 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLM mRNA] more ... CTD PMID:19339665 more ... GCLM Human liquiritigenin increases expression ISO Gclm (Rattus norvegicus) 6480464 liquiritigenin results in increased expression of GCLM protein CTD PMID:29908794 GCLM Human liquiritigenin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 liquiritigenin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA] CTD PMID:29908794 GCLM Human liquiritin increases expression ISO Gclm (Rattus norvegicus) 6480464 liquiritin results in increased expression of GCLM protein CTD PMID:29908794 GCLM Human liquiritin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA] CTD PMID:29908794 GCLM Human lithocholic acid affects expression EXP 6480464 Lithocholic Acid affects the expression of GCLM mRNA and Lithocholic Acid affects the expression of GCLM protein CTD PMID:20146260 GCLM Human lithocholic acid decreases expression ISO Gclm (Mus musculus) 6480464 Lithocholic Acid results in decreased expression of GCLM mRNA CTD PMID:29794447 GCLM Human lithocholic acid multiple interactions ISO Gclm (Mus musculus) 6480464 [Lithocholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA and Vardenafil Dihydrochloride inhibits the reaction [Lithocholic Acid results in decreased expression of GCLM mRNA] CTD PMID:17724089 and PMID:29794447 GCLM Human lithocholic acid increases expression EXP 6480464 Lithocholic Acid results in increased expression of GCLM protein CTD PMID:17724089 GCLM Human lithocholic acid multiple interactions EXP 6480464 [Lithocholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA more ... CTD PMID:17724089 GCLM Human luteolin increases expression ISO Gclm (Rattus norvegicus) 6480464 Luteolin results in increased expression of GCLM mRNA and Luteolin results in increased expression of GCLM protein CTD PMID:22864849 GCLM Human LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin results in increased expression of GCLM protein] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ursodeoxycholic Acid results in increased expression of GCLM mRNA] CTD PMID:19073151 more ... GCLM Human LY294002 multiple interactions ISO Gclm (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA]] CTD PMID:25895139 GCLM Human LY294002 decreases activity EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of GCLM protein CTD PMID:16972261 GCLM Human LY294002 decreases expression EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased expression of GCLM mRNA CTD PMID:19073151 GCLM Human lycopene increases expression ISO Gclm (Mus musculus) 6480464 Lycopene results in increased expression of GCLM protein CTD PMID:36216167 GCLM Human lycopene multiple interactions ISO Gclm (Mus musculus) 6480464 Lycopene inhibits the reaction [Atrazine results in increased expression of GCLM mRNA] and Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GCLM mRNA] CTD PMID:35917956 and PMID:36216167 GCLM Human malonaldehyde affects abundance EXP 6480464 GCLM gene polymorphism affects the abundance of Malondialdehyde CTD PMID:25728017 GCLM Human manganese atom multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of GCLM mRNA CTD PMID:38503349 GCLM Human manganese(0) multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of GCLM mRNA CTD PMID:38503349 GCLM Human manganese(II) chloride multiple interactions EXP 6480464 [manganese chloride results in increased abundance of Manganese] which results in decreased expression of GCLM mRNA CTD PMID:38503349 GCLM Human melatonin multiple interactions ISO Gclm (Mus musculus) 6480464 4-phenyl-2-propionamidotetraline inhibits the reaction [Melatonin inhibits the reaction [KL mutant form results in decreased expression of GCLM mRNA]] more ... CTD PMID:25550330 GCLM Human menadione increases expression ISO Gclm (Mus musculus) 6480464 Vitamin K 3 results in increased expression of GCLM mRNA CTD PMID:25270620 GCLM Human menadione increases expression EXP 6480464 Vitamin K 3 results in increased expression of GCLM mRNA CTD PMID:12414654 and PMID:23410634 GCLM Human mercaptopurine increases expression EXP 6480464 Mercaptopurine results in increased expression of GCLM mRNA CTD PMID:18222062 GCLM Human mercury atom decreases expression EXP 6480464 Mercury results in decreased expression of GCLM mRNA CTD PMID:19937285 GCLM Human mercury atom affects metabolic processing EXP 6480464 GCLM polymorphism affects the metabolism of Mercury CTD PMID:16961004 GCLM Human mercury atom affects abundance EXP 6480464 GCLM gene polymorphism affects the abundance of Mercury and GCLM protein affects the abundance of Mercury CTD PMID:18560528 and PMID:21925580 GCLM Human mercury dibromide increases expression EXP 6480464 mercuric bromide results in increased expression of GCLM mRNA CTD PMID:26272509 GCLM Human mercury dibromide multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 GCLM Human mercury dichloride increases expression ISO Gclm (Mus musculus) 6480464 Mercuric Chloride results in increased expression of GCLM mRNA CTD PMID:24039982 GCLM Human mercury dichloride multiple interactions EXP 6480464 [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 GCLM Human mercury dichloride multiple interactions ISO Gclm (Mus musculus) 6480464 ABCC2 gene mutant form promotes the reaction [Mercuric Chloride results in increased expression of GCLM mRNA] CTD PMID:24039982 GCLM Human mercury(0) decreases expression EXP 6480464 Mercury results in decreased expression of GCLM mRNA CTD PMID:19937285 GCLM Human mercury(0) affects metabolic processing EXP 6480464 GCLM polymorphism affects the metabolism of Mercury CTD PMID:16961004 GCLM Human mercury(0) affects abundance EXP 6480464 GCLM gene polymorphism affects the abundance of Mercury and GCLM protein affects the abundance of Mercury CTD PMID:18560528 and PMID:21925580 GCLM Human mesalamine multiple interactions EXP 6480464 Mesalamine promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:27818126 GCLM Human metam multiple interactions ISO Gclm (Mus musculus) 6480464 methyldithiocarbamate promotes the reaction [Lipopolysaccharides results in increased expression of GCLM mRNA] CTD PMID:19339665 GCLM Human metformin decreases expression ISO Gclm (Rattus norvegicus) 6480464 Metformin results in decreased expression of GCLM mRNA CTD PMID:25596134 GCLM Human metformin decreases expression EXP 6480464 Metformin results in decreased expression of GCLM mRNA CTD PMID:33838154 GCLM Human metformin increases expression EXP 6480464 Metformin results in increased expression of GCLM mRNA CTD PMID:25596134 GCLM Human methidathion decreases expression ISO Gclm (Mus musculus) 6480464 methidathion results in decreased expression of GCLM mRNA CTD PMID:34813904 GCLM Human methyl methacrylate increases expression ISO Gclm (Mus musculus) 6480464 Methylmethacrylate results in increased expression of GCLM mRNA CTD PMID:16916219 GCLM Human methyl methanesulfonate increases expression EXP 6480464 Methyl Methanesulfonate results in increased expression of GCLM mRNA CTD PMID:23649840 GCLM Human methyl salicylate increases expression EXP 6480464 methyl salicylate results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human methylene blue multiple interactions ISO Gclm (Mus musculus) 6480464 [Methylene Blue co-treated with MAPT protein mutant form] results in increased expression of GCLM mRNA CTD PMID:24556215 GCLM Human methylisothiazolinone increases expression EXP 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of GCLM mRNA CTD PMID:30806763 GCLM Human methylmercury chloride increases expression ISO Gclm (Mus musculus) 6480464 methylmercuric chloride results in increased expression of GCLM mRNA CTD PMID:20061341 GCLM Human methylmercury chloride multiple interactions ISO Gclm (Rattus norvegicus) 6480464 Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM mRNA] and Thioctic Acid inhibits the reaction [methylmercuric chloride results in increased expression of GCLM protein] CTD PMID:32061141 GCLM Human methylmercury chloride increases expression ISO Gclm (Rattus norvegicus) 6480464 methylmercuric chloride results in increased expression of GCLM mRNA and methylmercuric chloride results in increased expression of GCLM protein CTD PMID:32061141 GCLM Human methylmercury chloride multiple interactions EXP 6480464 [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 GCLM Human methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of GCLM mRNA CTD PMID:23179753 more ... GCLM Human metronidazole multiple interactions ISO Gclm (Mus musculus) 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36535435 GCLM Human mifepristone increases expression ISO Gclm (Mus musculus) 6480464 Mifepristone results in increased expression of GCLM protein CTD PMID:16840778 GCLM Human mifepristone multiple interactions ISO Gclm (Mus musculus) 6480464 Acetaminophen promotes the reaction [Mifepristone results in increased activity of [GCLC protein binds to GCLM protein]] and Mifepristone results in increased activity of [GCLC protein binds to GCLM protein] CTD PMID:16840778 GCLM Human monascin multiple interactions EXP 6480464 monascin inhibits the reaction [S100B protein results in decreased expression of GCLM mRNA] and NFE2L2 mutant form inhibits the reaction [monascin inhibits the reaction [S100B protein results in decreased expression of GCLM mRNA]] CTD PMID:23331247 GCLM Human mono(2-ethylhexyl) phthalate increases expression ISO Gclm (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of GCLM mRNA CTD PMID:34863575 GCLM Human monocrotaline multiple interactions ISO Gclm (Rattus norvegicus) 6480464 liquiritigenin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA] and liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GCLM mRNA] CTD PMID:29908794 GCLM Human monocrotaline decreases expression ISO Gclm (Rattus norvegicus) 6480464 Monocrotaline results in decreased expression of GCLM mRNA CTD PMID:29908794 GCLM Human motexafin gadolinium multiple interactions EXP 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GCLM mRNA CTD PMID:16357179 GCLM Human motexafin gadolinium increases expression EXP 6480464 motexafin gadolinium results in increased expression of GCLM mRNA CTD PMID:16357179 GCLM Human N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of GCLM mRNA] and Acetylcysteine inhibits the reaction [elesclomol results in increased expression of GCLM mRNA] CTD PMID:18723479 and PMID:19350554 GCLM Human N-acetyl-L-cysteine affects response to substance ISO Gclm (Mus musculus) 6480464 GCLM protein affects the susceptibility to Acetylcysteine CTD PMID:17584759 GCLM Human N-acetyl-L-cysteine multiple interactions ISO Gclm (Mus musculus) 6480464 [Acetylcysteine co-treated with Acetaminophen] results in decreased expression of GCLM mRNA and Acetylcysteine inhibits the reaction [arsenite results in increased expression of GCLM mRNA] CTD PMID:19328227 and PMID:37598316 GCLM Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO Gclm (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM mRNA CTD PMID:20061341 GCLM Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM mRNA and [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM protein CTD PMID:33434570 GCLM Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM mRNA and benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM protein CTD PMID:33434570 GCLM Human N-methyl-4-phenylpyridinium decreases expression ISO Gclm (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of GCLM protein CTD PMID:26558463 GCLM Human N-nitrosodiethylamine multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased expression of GCLM mRNA CTD PMID:16158176 GCLM Human N-nitrosomorpholine increases expression ISO Gclm (Rattus norvegicus) 6480464 N-nitrosomorpholine results in increased expression of GCLM protein CTD PMID:19716841 GCLM Human N-tosyl-L-phenylalanyl chloromethyl ketone increases expression ISO Gclm (Mus musculus) 6480464 Tosylphenylalanyl Chloromethyl Ketone results in increased expression of GCLM mRNA CTD PMID:22851183 GCLM Human N-tosyl-L-phenylalanyl chloromethyl ketone increases expression EXP 6480464 Tosylphenylalanyl Chloromethyl Ketone results in increased expression of GCLM mRNA CTD PMID:22851183 GCLM Human naphthalene decreases expression ISO Gclm (Mus musculus) 6480464 naphthalene results in decreased expression of GCLM mRNA CTD PMID:31020322 GCLM Human naproxen increases expression EXP 6480464 Naproxen results in increased expression of GCLM mRNA CTD PMID:11909699 GCLM Human nefazodone increases expression ISO Gclm (Rattus norvegicus) 6480464 nefazodone results in increased expression of GCLM mRNA CTD PMID:24136188 GCLM Human neoastilbin multiple interactions EXP 6480464 astilbin promotes the reaction [Cisplatin results in increased expression of GCLM mRNA] CTD PMID:29471006 GCLM Human neomycin multiple interactions ISO Gclm (Mus musculus) 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36535435 GCLM Human nickel atom increases expression EXP 6480464 Nickel results in increased expression of GCLM mRNA CTD PMID:25583101 GCLM Human nickel dichloride increases expression ISO Gclm (Rattus norvegicus) 6480464 nickel chloride results in increased expression of GCLM mRNA CTD PMID:22110744 GCLM Human nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of GCLM mRNA CTD PMID:16314067 and PMID:20566472 GCLM Human niclosamide decreases expression EXP 6480464 Niclosamide results in decreased expression of GCLM mRNA CTD PMID:36318118 GCLM Human nilotinib multiple interactions EXP 6480464 Arsenic Trioxide promotes the reaction [nilotinib results in increased expression of GCLM mRNA] CTD PMID:23883479 GCLM Human nilotinib increases expression EXP 6480464 nilotinib results in increased expression of GCLM mRNA CTD PMID:23883479 GCLM Human nimesulide increases expression ISO Gclm (Rattus norvegicus) 6480464 nimesulide results in increased expression of GCLM mRNA CTD PMID:24136188 GCLM Human nitisinone multiple interactions ISO Gclm (Mus musculus) 6480464 [nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLM mRNA CTD PMID:12899938 GCLM Human nitric oxide multiple interactions EXP 6480464 GCLM gene SNP affects the abundance of and affects the activity of and affects the susceptibility to Nitric Oxide CTD PMID:12975258 GCLM Human nitrogen dioxide decreases expression ISO Gclm (Rattus norvegicus) 6480464 Nitrogen Dioxide results in decreased expression of GCLM mRNA CTD PMID:16049373 GCLM Human Nonidet P-40 increases expression EXP 6480464 Nonidet P-40 results in increased expression of GCLM mRNA CTD PMID:26552463 GCLM Human Nutlin-3 multiple interactions EXP 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of GCLM protein CTD PMID:38460933 GCLM Human obeticholic acid increases expression ISO Gclm (Mus musculus) 6480464 obeticholic acid results in increased expression of GCLM mRNA CTD PMID:26655953 GCLM Human ochratoxin A decreases expression ISO Gclm (Rattus norvegicus) 6480464 ochratoxin A results in decreased expression of GCLM mRNA CTD PMID:16251485 and PMID:18417182 GCLM Human ochratoxin A decreases expression EXP 6480464 ochratoxin A results in decreased expression of GCLM mRNA CTD PMID:30559759 GCLM Human ochratoxin A affects expression EXP 6480464 ochratoxin A affects the expression of GCLM mRNA CTD PMID:30008028 GCLM Human oleanolic acid increases expression ISO Gclm (Mus musculus) 6480464 Oleanolic Acid results in increased expression of GCLM mRNA CTD PMID:18706400 GCLM Human oleic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein and Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein] CTD PMID:36905866 GCLM Human organoselenium compound multiple interactions EXP 6480464 [Organoselenium Compounds binds to Copper] which results in increased expression of GCLM mRNA CTD PMID:25167922 GCLM Human oxaliplatin decreases expression ISO Gclm (Rattus norvegicus) 6480464 oxaliplatin results in decreased expression of GCLM mRNA CTD PMID:25729387 GCLM Human oxaliplatin multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of GCLM mRNA CTD PMID:25729387 GCLM Human oxidopamine increases expression EXP 6480464 Oxidopamine results in increased expression of GCLM mRNA CTD PMID:33486071 GCLM Human oxidopamine decreases expression ISO Gclm (Rattus norvegicus) 6480464 Oxidopamine results in decreased expression of GCLM protein CTD PMID:25446857 GCLM Human oxidopamine multiple interactions EXP 6480464 AL 8810 inhibits the reaction [fluprostenol promotes the reaction [Oxidopamine results in increased expression of GCLM mRNA]] more ... CTD PMID:25446857 and PMID:33486071 GCLM Human oxidopamine decreases expression EXP 6480464 Oxidopamine results in decreased expression of GCLM protein CTD PMID:25446857 GCLM Human oxidopamine multiple interactions ISO Gclm (Rattus norvegicus) 6480464 salvin inhibits the reaction [Oxidopamine results in decreased expression of GCLM protein] CTD PMID:25446857 GCLM Human ozone affects response to substance ISO Gclm (Mus musculus) 6480464 GCLM gene mutant form affects the susceptibility to Ozone CTD PMID:20417186 GCLM Human ozone multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Ozone co-treated with Chlorine] results in decreased expression of GCLM mRNA CTD PMID:18636392 GCLM Human ozone multiple interactions ISO Gclm (Mus musculus) 6480464 GCLM gene mutant form promotes the reaction [Ozone results in increased expression of MT1 mRNA] more ... CTD PMID:20417186 GCLM Human p-chloromercuribenzoic acid increases expression EXP 6480464 p-Chloromercuribenzoic Acid results in increased expression of GCLM mRNA CTD PMID:26272509 GCLM Human p-chloromercuribenzoic acid multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 GCLM Human p-toluidine increases expression ISO Gclm (Rattus norvegicus) 6480464 4-toluidine results in increased expression of GCLM mRNA CTD PMID:27638505 GCLM Human para-Cresidine increases expression EXP 6480464 cresidine results in increased expression of GCLM mRNA CTD PMID:26198647 GCLM Human paracetamol multiple interactions EXP 6480464 [Acetaminophen co-treated with Quercetin] results in increased expression of GCLM mRNA more ... CTD PMID:25881548 more ... GCLM Human paracetamol decreases expression ISO Gclm (Mus musculus) 6480464 Acetaminophen results in decreased expression of GCLM mRNA CTD PMID:25818464 more ... GCLM Human paracetamol affects response to substance ISO Gclm (Mus musculus) 6480464 GCLM protein affects the susceptibility to Acetaminophen CTD PMID:17584759 GCLM Human paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of GCLM mRNA and Acetaminophen results in increased expression of GCLM protein CTD PMID:21420995 more ... GCLM Human paracetamol increases expression ISO Gclm (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of GCLM mRNA CTD PMID:11245408 more ... GCLM Human paracetamol decreases response to substance ISO Gclm (Mus musculus) 6480464 GCLM protein results in decreased susceptibility to Acetaminophen CTD PMID:18642143 GCLM Human paracetamol increases expression ISO Gclm (Mus musculus) 6480464 Acetaminophen results in increased expression of GCLM mRNA and Acetaminophen results in increased expression of GCLM protein CTD PMID:18468992 more ... GCLM Human paracetamol multiple interactions ISO Gclm (Mus musculus) 6480464 [Acetaminophen co-treated with amlexanox co-treated with dorsomorphin] affects the expression of GCLM mRNA more ... CTD PMID:16840778 more ... GCLM Human paracetamol affects expression ISO Gclm (Mus musculus) 6480464 Acetaminophen affects the expression of GCLM mRNA CTD PMID:17562736 GCLM Human paraoxon increases expression EXP 6480464 Paraoxon results in increased expression of GCLM mRNA CTD PMID:24413757 GCLM Human paraquat increases response to substance ISO Gclm (Mus musculus) 6480464 GCLM gene mutant form results in increased susceptibility to Paraquat CTD PMID:23704229 GCLM Human paraquat multiple interactions ISO Gclm (Rattus norvegicus) 6480464 ginkgolide C inhibits the reaction [Paraquat results in decreased expression of GCLM protein] CTD PMID:35707280 GCLM Human paraquat increases expression EXP 6480464 Paraquat results in increased expression of GCLM mRNA CTD PMID:34097952 and PMID:35182771 GCLM Human paraquat increases expression ISO Gclm (Mus musculus) 6480464 Paraquat results in increased expression of GCLM mRNA CTD PMID:31216030 GCLM Human paraquat decreases expression ISO Gclm (Rattus norvegicus) 6480464 Paraquat results in decreased expression of GCLM protein CTD PMID:27993944 and PMID:35707280 GCLM Human paraquat increases expression ISO Gclm (Rattus norvegicus) 6480464 Paraquat results in increased expression of GCLM mRNA CTD PMID:28467894 GCLM Human paraquat multiple interactions EXP 6480464 [alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLM mRNA CTD PMID:24530478 GCLM Human paraquat multiple interactions ISO Gclm (Mus musculus) 6480464 [GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased abundance of Dopamine more ... CTD PMID:23704229 and PMID:31216030 GCLM Human PCB138 decreases expression ISO Gclm (Rattus norvegicus) 6480464 2 more ... CTD PMID:23829299 GCLM Human pentachlorophenol increases expression ISO Gclm (Mus musculus) 6480464 Pentachlorophenol results in increased expression of GCLM mRNA CTD PMID:23892564 GCLM Human perfluorodecanoic acid increases expression EXP 6480464 perfluorodecanoic acid results in increased expression of GCLM mRNA CTD PMID:23567314 GCLM Human perfluorohexanesulfonic acid increases expression ISO Gclm (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of GCLM mRNA CTD PMID:37995155 GCLM Human perfluorononanoic acid increases expression EXP 6480464 perfluoro-n-nonanoic acid results in increased expression of GCLM mRNA CTD PMID:32588087 GCLM Human perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of GCLM mRNA CTD PMID:33772556 GCLM Human perfluorooctanoic acid decreases expression ISO Gclm (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of GCLM mRNA CTD PMID:30547568 GCLM Human perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of GCLM mRNA CTD PMID:33772556 GCLM Human phenobarbital increases expression ISO Gclm (Rattus norvegicus) 6480464 Phenobarbital results in increased expression of GCLM mRNA CTD PMID:19162173 GCLM Human phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of GCLM mRNA CTD PMID:19159669 GCLM Human phenol increases expression EXP 6480464 Phenol results in increased expression of GCLM mRNA CTD PMID:26198647 GCLM Human phenoxymethylpenicillin increases expression EXP 6480464 Penicillin V results in increased expression of GCLM mRNA CTD PMID:22609641 GCLM Human phenyl benzoate increases expression EXP 6480464 diphenylcarboxylate results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of GCLM mRNA CTD PMID:26272509 GCLM Human phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 GCLM Human phenytoin increases expression ISO Gclm (Rattus norvegicus) 6480464 Phenytoin results in increased expression of GCLM mRNA CTD PMID:20345932 GCLM Human phlorizin decreases expression ISO Gclm (Mus musculus) 6480464 Phlorhizin results in decreased expression of GCLM mRNA CTD PMID:22538082 GCLM Human phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA] and Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA] CTD PMID:24632381 GCLM Human phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA CTD PMID:24632381 GCLM Human phorone affects expression ISO Gclm (Rattus norvegicus) 6480464 phorone affects the expression of GCLM mRNA CTD PMID:18198479 GCLM Human phosgene affects expression ISO Gclm (Mus musculus) 6480464 Phosgene affects the expression of GCLM mRNA CTD PMID:16300373 GCLM Human picoxystrobin increases expression EXP 6480464 picoxystrobin results in increased expression of GCLM mRNA CTD PMID:33512557 GCLM Human plumbagin increases expression EXP 6480464 plumbagin results in increased expression of GCLM mRNA CTD PMID:20028456 GCLM Human polymyxin B2 increases expression EXP 6480464 Polymyxin B results in increased expression of GCLM mRNA CTD PMID:37088170 GCLM Human potassium bromate increases expression EXP 6480464 potassium bromate results in increased expression of GCLM mRNA CTD PMID:30008028 and PMID:30559759 GCLM Human potassium bromate increases methylation EXP 6480464 potassium bromate results in increased methylation of GCLM promoter CTD PMID:30559759 GCLM Human pregnenolone 16alpha-carbonitrile increases expression ISO Gclm (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in increased expression of GCLM mRNA CTD PMID:19162173 GCLM Human procyanidin B3 multiple interactions ISO Gclm (Mus musculus) 6480464 [Eicosapentaenoic Acid co-treated with procyanidin B3 co-treated with Lipopolysaccharides] results in increased expression of GCLM mRNA CTD PMID:22169119 GCLM Human propan-2-ol increases expression EXP 6480464 2-Propanol results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human prostaglandin J2 increases expression ISO Gclm (Rattus norvegicus) 6480464 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GCLM mRNA and 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GCLM protein CTD PMID:18332871 GCLM Human Prothionamide multiple interactions EXP 6480464 [Prothionamide co-treated with osteum] results in increased expression of GCLM mRNA CTD PMID:38631510 GCLM Human purine-6-thiol increases expression EXP 6480464 Mercaptopurine results in increased expression of GCLM mRNA CTD PMID:18222062 GCLM Human pyrimidifen increases expression EXP 6480464 pyrimidifen results in increased expression of GCLM mRNA CTD PMID:33512557 GCLM Human quercetin increases expression ISO Gclm (Mus musculus) 6480464 Quercetin results in increased expression of GCLM mRNA and Quercetin results in increased expression of GCLM protein CTD PMID:19183254 and PMID:27777014 GCLM Human quercetin increases activity ISO Gclm (Mus musculus) 6480464 Quercetin analog results in increased activity of GCLM protein CTD PMID:27777014 GCLM Human quercetin increases expression EXP 6480464 Quercetin results in increased expression of GCLM mRNA and Quercetin results in increased expression of GCLM protein CTD PMID:19576171 more ... GCLM Human quercetin multiple interactions EXP 6480464 [Acetaminophen co-treated with Quercetin] results in increased expression of GCLM mRNA more ... CTD PMID:22197970 and PMID:25881548 GCLM Human rac-lactic acid increases expression EXP 6480464 Lactic Acid results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human reactive oxygen species decreases abundance EXP 6480464 GCLM gene SNP results in decreased abundance of Reactive Oxygen Species CTD PMID:32715377 GCLM Human reactive oxygen species increases expression EXP 6480464 Reactive Oxygen Species results in increased expression of GCLM mRNA CTD PMID:25800948 GCLM Human reactive oxygen species multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Buthionine Sulfoximine results in decreased activity of [GCLC protein binds to GCLM protein]] inhibits the reaction [chrysin inhibits the reaction [tert-Butylhydroperoxide results in increased chemical synthesis of Reactive Oxygen Species]] CTD PMID:22864849 GCLM Human resveratrol multiple interactions EXP 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of GCLM mRNA and resveratrol promotes the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of GCLM mRNA] CTD PMID:19167446 and PMID:27818126 GCLM Human resveratrol increases expression ISO Gclm (Mus musculus) 6480464 resveratrol results in increased expression of GCLM mRNA CTD PMID:25808216 GCLM Human rotenone increases expression ISO Gclm (Mus musculus) 6480464 Rotenone results in increased expression of GCLM mRNA CTD PMID:17657281 GCLM Human rotenone increases expression EXP 6480464 Rotenone results in increased expression of GCLM mRNA CTD PMID:33512557 GCLM Human rotenone affects expression ISO Gclm (Mus musculus) 6480464 Rotenone affects the expression of GCLM mRNA CTD PMID:23186747 GCLM Human rottlerin multiple interactions ISO Gclm (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA]] more ... CTD PMID:25895139 more ... GCLM Human S-(1,2-dichlorovinyl)-L-cysteine multiple interactions EXP 6480464 [S-(1 more ... CTD PMID:35811015 GCLM Human S-(1,2-dichlorovinyl)-L-cysteine increases expression EXP 6480464 S-(1 and 2-dichlorovinyl)cysteine results in increased expression of GCLM mRNA CTD PMID:35811015 and PMID:36576512 GCLM Human S-(1,2-Dichlorovinyl)glutathione increases expression EXP 6480464 S-(1 and 2-dichlorovinyl)glutathione results in increased expression of GCLM mRNA CTD PMID:36576512 GCLM Human S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO Gclm (Rattus norvegicus) 6480464 Buthionine Sulfoximine results in increased expression of GCLM mRNA CTD PMID:10978506 and PMID:19010381 GCLM Human S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP 6480464 Buthionine Sulfoximine inhibits the reaction [[Lithocholic Acid results in increased expression of GCLM protein] which results in increased abundance of Glutathione] CTD PMID:17724089 GCLM Human S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Buthionine Sulfoximine results in decreased activity of [GCLC protein binds to GCLM protein]] inhibits the reaction [chrysin inhibits the reaction [tert-Butylhydroperoxide results in increased chemical synthesis of Reactive Oxygen Species]] CTD PMID:22864849 GCLM Human SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [Quercetin results in increased expression of GCLM mRNA] CTD PMID:22197970 GCLM Human SB 431542 multiple interactions EXP 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:34480604 GCLM Human Securinine increases expression EXP 6480464 securinine results in increased expression of GCLM mRNA CTD PMID:32662633 GCLM Human sevoflurane multiple interactions ISO Gclm (Mus musculus) 6480464 alpha-solamargine inhibits the reaction [Sevoflurane results in decreased expression of GCLM mRNA] CTD PMID:35350913 GCLM Human sevoflurane decreases expression ISO Gclm (Mus musculus) 6480464 Sevoflurane results in decreased expression of GCLM mRNA CTD PMID:35350913 GCLM Human silicon dioxide multiple interactions ISO Gclm (Mus musculus) 6480464 [Silicon Dioxide co-treated with Vitamin D] results in increased expression of GCLM mRNA CTD PMID:30698894 GCLM Human silicon dioxide increases expression ISO Gclm (Mus musculus) 6480464 Silicon Dioxide results in increased expression of GCLM mRNA CTD PMID:30698894 GCLM Human silver atom increases expression EXP 6480464 Silver results in increased expression of GCLM mRNA CTD PMID:22036727 more ... GCLM Human silver atom increases expression ISO Gclm (Mus musculus) 6480464 Silver results in increased expression of GCLM mRNA CTD PMID:27131904 GCLM Human silver atom multiple interactions EXP 6480464 NFE2L2 protein affects the reaction [Silver results in increased expression of GCLM mRNA] CTD PMID:22546375 GCLM Human silver(0) multiple interactions EXP 6480464 NFE2L2 protein affects the reaction [Silver results in increased expression of GCLM mRNA] CTD PMID:22546375 GCLM Human silver(0) increases expression ISO Gclm (Mus musculus) 6480464 Silver results in increased expression of GCLM mRNA CTD PMID:27131904 GCLM Human silver(0) increases expression EXP 6480464 Silver results in increased expression of GCLM mRNA CTD PMID:22036727 more ... GCLM Human SL-327 multiple interactions ISO Gclm (Mus musculus) 6480464 SL 327 inhibits the reaction [Melatonin inhibits the reaction [KL mutant form results in decreased expression of GCLM mRNA]] CTD PMID:25550330 GCLM Human sodium arsenate multiple interactions EXP 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA and [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of GCLM protein CTD PMID:32525701 and PMID:33434570 GCLM Human sodium arsenite multiple interactions EXP 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of GCLM mRNA more ... CTD PMID:20805060 more ... GCLM Human sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of GCLM mRNA CTD PMID:35298964 and PMID:37956786 GCLM Human sodium arsenite increases expression ISO Gclm (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of GCLM mRNA and sodium arsenite results in increased expression of GCLM protein CTD PMID:21465251 GCLM Human sodium arsenite affects expression ISO Gclm (Rattus norvegicus) 6480464 sodium arsenite affects the expression of GCLM mRNA CTD PMID:25625412 GCLM Human sodium arsenite increases expression ISO Gclm (Mus musculus) 6480464 sodium arsenite results in increased expression of GCLM mRNA and sodium arsenite results in increased expression of GCLM protein CTD PMID:16014739 more ... GCLM Human sodium arsenite increases response to substance ISO Gclm (Mus musculus) 6480464 GCLM gene mutant form results in increased susceptibility to sodium arsenite CTD PMID:16014739 GCLM Human sodium arsenite multiple interactions ISO Gclm (Mus musculus) 6480464 [GCLM co-treated with GCLC] inhibits the reaction [sodium arsenite results in increased activity of and results in increased cleavage of CASP3 protein] more ... CTD PMID:20006689 and PMID:34272803 GCLM Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of GCLM mRNA and sodium arsenite results in increased expression of GCLM protein CTD PMID:12679051 more ... GCLM Human sodium dichromate increases expression ISO Gclm (Mus musculus) 6480464 sodium bichromate results in increased expression of GCLM mRNA CTD PMID:22155349 GCLM Human sodium dichromate decreases expression ISO Gclm (Mus musculus) 6480464 sodium bichromate results in decreased expression of GCLM mRNA CTD PMID:22155349 GCLM Human sodium dodecyl sulfate increases expression EXP 6480464 Sodium Dodecyl Sulfate results in increased expression of GCLM mRNA CTD PMID:20566472 GCLM Human Sodium oleate multiple interactions EXP 6480464 [etomoxir co-treated with osteum] results in increased expression of GCLM mRNA more ... CTD PMID:38631510 GCLM Human spermidine multiple interactions ISO Gclm (Mus musculus) 6480464 pimagedine inhibits the reaction [Spermidine results in increased expression of GCLM mRNA] CTD PMID:12763045 GCLM Human spermidine increases expression ISO Gclm (Mus musculus) 6480464 Spermidine results in increased expression of GCLM mRNA CTD PMID:12763045 GCLM Human staurosporine multiple interactions EXP 6480464 Staurosporine promotes the reaction [MYC protein binds to GCLM promoter] CTD PMID:17628013 GCLM Human streptozocin multiple interactions ISO Gclm (Mus musculus) 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLM mRNA CTD PMID:33359794 GCLM Human succimer multiple interactions ISO Gclm (Mus musculus) 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of GCLM mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of GCLM mRNA CTD PMID:21641980 and PMID:26378955 GCLM Human sulforaphane multiple interactions ISO Gclm (Mus musculus) 6480464 NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GCLM mRNA] more ... CTD PMID:20932822 more ... GCLM Human sulforaphane decreases expression EXP 6480464 sulforaphane results in decreased expression of GCLM mRNA CTD PMID:35724838 GCLM Human sulforaphane multiple interactions EXP 6480464 NFE2L2 protein affects the reaction [sulforaphane results in increased expression of GCLM protein] CTD PMID:35227738 GCLM Human sulforaphane increases expression ISO Gclm (Mus musculus) 6480464 sulforaphane results in increased expression of GCLM mRNA and sulforaphane results in increased expression of GCLM protein CTD PMID:19071154 more ... GCLM Human sulforaphane increases expression EXP 6480464 sulforaphane results in increased expression of GCLM more ... CTD PMID:20442190 more ... GCLM Human sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of GCLM mRNA CTD PMID:31533062 GCLM Human Sunset Yellow FCF multiple interactions EXP 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of GCLM mRNA CTD PMID:33819548 GCLM Human suprofen increases expression EXP 6480464 Suprofen results in increased expression of GCLM mRNA CTD PMID:11909699 GCLM Human T-2 toxin decreases expression ISO Gclm (Mus musculus) 6480464 T-2 Toxin results in decreased expression of GCLM mRNA CTD PMID:20854872 GCLM Human T-2 toxin increases expression ISO Gclm (Mus musculus) 6480464 T-2 Toxin results in increased expression of GCLM mRNA CTD PMID:33508416 GCLM Human tartrazine multiple interactions EXP 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of GCLM mRNA CTD PMID:33819548 GCLM Human tebufenpyrad increases expression EXP 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of GCLM mRNA CTD PMID:33512557 GCLM Human tectorigenin multiple interactions ISO Gclm (Mus musculus) 6480464 [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of GCLM protein and tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of GCLM mRNA] CTD PMID:37348807 GCLM Human temozolomide increases expression EXP 6480464 Temozolomide results in increased expression of GCLM mRNA CTD PMID:31758290 GCLM Human tert-butyl hydroperoxide multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [Apigenin results in increased expression of GCLM mRNA] which results in decreased susceptibility to tert-Butylhydroperoxide more ... CTD PMID:22864849 GCLM Human tert-butyl hydroperoxide increases expression ISO Gclm (Mus musculus) 6480464 tert-Butylhydroperoxide results in increased expression of GCLM mRNA CTD PMID:30547568 GCLM Human tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of GCLM mRNA CTD PMID:12414654 more ... GCLM Human tetrachloromethane affects expression ISO Gclm (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of GCLM mRNA CTD PMID:17484886 GCLM Human tetrachloromethane increases expression ISO Gclm (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of GCLM mRNA CTD PMID:32063085 GCLM Human tetrachloromethane multiple interactions ISO Gclm (Mus musculus) 6480464 AK-1 compound promotes the reaction [Carbon Tetrachloride results in increased expression of GCLM mRNA] more ... CTD PMID:27477297 more ... GCLM Human tetrachloromethane decreases expression ISO Gclm (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of GCLM mRNA and Carbon Tetrachloride results in decreased expression of GCLM protein CTD PMID:17484886 more ... GCLM Human tetrachloromethane affects expression ISO Gclm (Rattus norvegicus) 6480464 Carbon Tetrachloride affects the expression of GCLM mRNA CTD PMID:15963342 GCLM Human tetramethylpyrazine multiple interactions ISO Gclm (Mus musculus) 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM mRNA]] more ... CTD PMID:27477297 GCLM Human thifluzamide increases expression EXP 6480464 thifluzamide results in increased expression of GCLM mRNA CTD PMID:33512557 GCLM Human thioacetamide increases expression ISO Gclm (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of GCLM mRNA and Thioacetamide results in increased expression of GCLM protein CTD PMID:10486302 more ... GCLM Human thioacetamide decreases expression ISO Gclm (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of GCLM mRNA CTD PMID:34492290 GCLM Human thiram increases expression EXP 6480464 Thiram results in increased expression of GCLM mRNA CTD PMID:23999411 more ... GCLM Human titanium dioxide multiple interactions ISO Gclm (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of GCLM mRNA CTD PMID:29950665 GCLM Human titanium dioxide decreases methylation ISO Gclm (Mus musculus) 6480464 titanium dioxide results in decreased methylation of GCLM gene CTD PMID:35295148 GCLM Human toluene increases expression EXP 6480464 Toluene results in increased expression of GCLM mRNA CTD PMID:28245982 GCLM Human topotecan multiple interactions ISO Gclm (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of GCLM mRNA CTD PMID:25729387 GCLM Human topotecan decreases expression ISO Gclm (Rattus norvegicus) 6480464 Topotecan results in decreased expression of GCLM mRNA CTD PMID:25729387 GCLM Human trans-chalcone increases expression EXP 6480464 Chalcone analog results in increased expression of GCLM mRNA and Chalcone analog results in increased expression of GCLM protein CTD PMID:31299238 GCLM Human trans-isoeugenol increases expression EXP 6480464 isoeugenol results in increased expression of GCLM mRNA CTD PMID:20566472 more ... GCLM Human triacsin C increases expression EXP 6480464 triacsin C results in increased expression of GCLM mRNA CTD PMID:16704987 GCLM Human tributylstannane multiple interactions ISO Gclm (Mus musculus) 6480464 PRKCD gene mutant form promotes the reaction [tributyltin results in increased expression of GCLM mRNA] CTD PMID:25895139 GCLM Human Tributyltin oxide decreases expression EXP 6480464 bis(tri-n-butyltin)oxide results in decreased expression of GCLM mRNA CTD PMID:26198647 GCLM Human Tributyltin oxide increases expression EXP 6480464 bis(tri-n-butyltin)oxide results in increased expression of GCLM mRNA CTD PMID:21601586 GCLM Human Tributyltin oxide increases expression ISO Gclm (Mus musculus) 6480464 bis(tri-n-butyltin)oxide results in increased expression of GCLM mRNA CTD PMID:21601586 GCLM Human trichloroethene increases expression ISO Gclm (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of GCLM mRNA CTD PMID:19448997 and PMID:33387578 GCLM Human trichostatin A affects expression EXP 6480464 trichostatin A affects the expression of GCLM mRNA CTD PMID:28542535 GCLM Human triclocarban multiple interactions EXP 6480464 [triclocarban co-treated with osteum] results in increased expression of GCLM mRNA CTD PMID:38631510 GCLM Human trimethyltin multiple interactions ISO Gclm (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA]] and rottlerin promotes the reaction [trimethyltin results in increased expression of GCLM mRNA] CTD PMID:25895139 GCLM Human trimethyltin increases expression ISO Gclm (Mus musculus) 6480464 trimethyltin results in increased expression of GCLM mRNA CTD PMID:25895139 GCLM Human triphenyl phosphate increases expression ISO Gclm (Rattus norvegicus) 6480464 triphenyl phosphate results in increased expression of GCLM mRNA CTD PMID:30589522 GCLM Human triphenyl phosphate affects expression EXP 6480464 triphenyl phosphate affects the expression of GCLM mRNA CTD PMID:37042841 GCLM Human tris(2-butoxyethyl) phosphate decreases response to substance ISO Gclm (Mus musculus) 6480464 GCLM protein results in decreased susceptibility to tris(2-butoxyethyl) phosphate CTD PMID:25797475 GCLM Human Tungsten carbide multiple interactions EXP 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of GCLM mRNA CTD PMID:23052192 GCLM Human tunicamycin decreases expression ISO Gclm (Mus musculus) 6480464 Tunicamycin results in decreased expression of GCLM mRNA CTD PMID:17127020 GCLM Human tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of GCLM mRNA CTD PMID:36586010 GCLM Human tunicamycin decreases expression EXP 6480464 Tunicamycin results in decreased expression of GCLM mRNA CTD PMID:29453283 GCLM Human undecanal increases expression EXP 6480464 undecanal analog results in increased expression of GCLM mRNA CTD PMID:27965148 GCLM Human ursodeoxycholic acid multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Ursodeoxycholic Acid results in increased expression of GCLM mRNA] and Ursodeoxycholic Acid inhibits the reaction [Iron results in decreased expression of GCLM mRNA] CTD PMID:19073151 GCLM Human ursodeoxycholic acid increases expression EXP 6480464 Ursodeoxycholic Acid results in increased expression of GCLM mRNA CTD PMID:19073151 GCLM Human valdecoxib increases expression ISO Gclm (Rattus norvegicus) 6480464 valdecoxib results in increased expression of GCLM mRNA CTD PMID:24136188 GCLM Human valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GCLM mRNA CTD PMID:27188386 GCLM Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of GCLM mRNA CTD PMID:23179753 more ... GCLM Human vancomycin multiple interactions ISO Gclm (Mus musculus) 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36535435 GCLM Human vanillin increases expression EXP 6480464 vanillin results in increased expression of GCLM mRNA CTD PMID:17178418 GCLM Human vincristine multiple interactions EXP 6480464 [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine CTD PMID:10900222 GCLM Human vincristine decreases expression EXP 6480464 Vincristine results in decreased expression of GCLM mRNA CTD PMID:23649840 GCLM Human vitamin D increases expression ISO Gclm (Mus musculus) 6480464 Vitamin D results in increased expression of GCLM mRNA CTD PMID:30698894 GCLM Human vitamin D multiple interactions ISO Gclm (Mus musculus) 6480464 [Particulate Matter co-treated with Vitamin D] results in increased expression of GCLM mRNA and [Silicon Dioxide co-treated with Vitamin D] results in increased expression of GCLM mRNA CTD PMID:30698894 GCLM Human vitamin E multiple interactions ISO Gclm (Rattus norvegicus) 6480464 Vitamin E affects the reaction [[REL binds to GCLM promoter] which affects the expression of GCLM mRNA] CTD PMID:16298738 GCLM Human vitamin E affects expression ISO Gclm (Rattus norvegicus) 6480464 Vitamin E affects the expression of GCLM mRNA CTD PMID:16298738 and PMID:20447326 GCLM Human wortmannin multiple interactions EXP 6480464 Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]] CTD PMID:34077701 GCLM Human XAV939 multiple interactions EXP 6480464 [[ascorbate-2-phosphate co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA and [[Ascorbic Acid co-treated with Chir 99021 co-treated with XAV939 co-treated with BMP4 protein co-treated with FGF1 protein co-treated with WNT3A protein co-treated with HGF protein] co-treated with [INHBA protein binds to INHBA protein]] results in increased expression of GCLM mRNA CTD PMID:34480604 GCLM Human zinc acetate increases expression EXP 6480464 Zinc Acetate results in increased expression of GCLM mRNA CTD PMID:16357179 GCLM Human zinc acetate multiple interactions EXP 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GCLM mRNA CTD PMID:16357179 GCLM Human zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of GCLM mRNA and Zinc deficiency results in decreased expression of GCLM protein CTD PMID:23377617 GCLM Human zinc atom decreases expression ISO Gclm (Rattus norvegicus) 6480464 Zinc deficiency results in decreased expression of GCLM mRNA and Zinc deficiency results in decreased expression of GCLM protein CTD PMID:23377617 GCLM Human zinc dichloride multiple interactions EXP 6480464 zinc chloride promotes the reaction [SLC39A2 protein results in increased expression of GCLM mRNA] CTD PMID:18385089 GCLM Human zinc oxide multiple interactions ISO Gclm (Mus musculus) 6480464 [Vancomycin co-treated with Neomycin co-treated with Metronidazole] promotes the reaction [Zinc Oxide analog results in increased expression of GCLM protein] more ... CTD PMID:30500950 more ... GCLM Human zinc oxide increases expression ISO Gclm (Mus musculus) 6480464 Zinc Oxide analog results in increased expression of GCLM mRNA and Zinc Oxide analog results in increased expression of GCLM protein CTD PMID:35247504 more ... GCLM Human zinc oxide multiple interactions EXP 6480464 RU.521 inhibits the reaction [Zinc Oxide analog results in increased expression of GCLM protein] CTD PMID:36368621 GCLM Human zinc oxide increases expression EXP 6480464 Zinc Oxide analog results in increased expression of GCLM protein CTD PMID:36368621 GCLM Human zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of GCLM mRNA and Zinc deficiency results in decreased expression of GCLM protein CTD PMID:23377617 GCLM Human zinc(0) decreases expression ISO Gclm (Rattus norvegicus) 6480464 Zinc deficiency results in decreased expression of GCLM mRNA and Zinc deficiency results in decreased expression of GCLM protein CTD PMID:23377617
