Il2rg (interleukin 2 receptor, gamma chain)

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Gene: Il2rg (interleukin 2 receptor, gamma chain) Mus musculus

Analyze

Symbol:

Il2rg

Name:

interleukin 2 receptor, gamma chain

RGD ID:

731534

MGI Page

MGI

Description:

Enables interleukin-2 binding activity. Acts upstream of or within positive regulation of gene expression and positive regulation of lymphocyte differentiation. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Human ortholog(s) of this gene implicated in X-linked severe combined immunodeficiency; combined T cell and B cell immunodeficiency; and severe combined immunodeficiency. Orthologous to human IL2RG (interleukin 2 receptor subunit gamma).

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

[g]c; CD132; common cytokine receptor gamma chain; common cytokine receptor gamma chain variant b; common gamma chain; cytokine receptor common subunit gamma; gamm; gamma C receptor; gamma(; gamma(c); gammaC; gc; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; interleukin-2 receptor subunit gamma; p64

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	100,307,991 - 100,311,861 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	100,307,984 - 100,311,861 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	101,264,385 - 101,268,255 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	101,264,378 - 101,268,255 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	98,459,726 - 98,463,545 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	97,467,106 - 97,470,925 (-)	NCBI		MGSCv36	mm8
Celera	X	88,180,558 - 88,184,377 (-)	NCBI		Celera
Cytogenetic Map	X	D	NCBI
cM Map	X	43.9	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

combined T cell and B cell immunodeficiency (ISO)

COVID-19 (ISO)

Experimental Liver Cirrhosis (ISO)

FG Syndrome 1 (ISO)

genetic disease (ISO)

Immune Deficiency Disease (ISO)

severe combined immunodeficiency (ISO)

Sezary's disease (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

X-linked severe combined immunodeficiency (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP)

1-naphthyl isothiocyanate (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (ISO)

4-hydroxycyclophosphamide (ISO)

4-hydroxyphenyl retinamide (EXP)

acetamide (ISO)

acetylsalicylic acid (ISO)

afimoxifene (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (ISO)

amphetamine (ISO)

antirheumatic drug (ISO)

aripiprazole (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (ISO)

C60 fullerene (ISO)

calcitriol (ISO)

carbon nanotube (EXP)

ceric oxide (ISO)

chloroprene (EXP)

clothianidin (ISO)

Cuprizon (ISO)

dextran sulfate (EXP)

dichloromethane (ISO)

diclofenac (EXP)

ethylbenzene (ISO)

fluvastatin (ISO)

gentamycin (ISO)

lipopolysaccharide (EXP)

methotrexate (EXP)

mycophenolic acid (EXP)

N-nitrosodimethylamine (ISO)

neoechinulin A (EXP)

nickel atom (ISO)

nickel subsulfide (ISO)

oxaliplatin (ISO)

ozone (EXP,ISO)

paracetamol (ISO)

phosgene (EXP)

pirinixic acid (EXP)

prostaglandin E2 (ISO)

resveratrol (ISO)

S-adenosyl-L-methioninate (EXP)

S-adenosyl-L-methionine (EXP)

silicon dioxide (EXP,ISO)

sirolimus (EXP)

sodium arsenite (EXP)

sterigmatocystin (EXP)

tamibarotene (EXP)

tamoxifen (EXP)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (ISO)

toluene (ISO)

topotecan (ISO)

trichloroethene (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

B cell differentiation (IMP)

CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (IMP)

cytokine-mediated signaling pathway (IBA)

gene expression (IMP)

interleukin-15-mediated signaling pathway (ISO)

interleukin-2-mediated signaling pathway (ISO)

interleukin-9-mediated signaling pathway (ISO)

lymphocyte differentiation (IMP)

mature B cell differentiation (IMP)

positive regulation of B cell differentiation (IMP)

positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (IMP)

positive regulation of gene expression (IMP)

positive regulation of phagocytosis (ISO)

positive regulation of T cell differentiation in thymus (IMP)

regulation of gene expression (IMP)

T cell differentiation in thymus (IMP)

Cellular Component

cell surface (ISO)

endoplasmic reticulum (ISO)

external side of plasma membrane (IBA,IDA)

membrane (IEA)

nucleoplasm (ISO)

plasma membrane (ISO,TAS)

receptor complex (IBA)

Molecular Function

coreceptor activity (ISO)

cytokine binding (IBA)

cytokine receptor activity (IBA)

interleukin-15 receptor activity (ISO)

interleukin-2 binding (IPI)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

endocytosis pathway (IEA)

interleukin-12 signaling pathway (ISO)

interleukin-2 signaling pathway (ISO)

interleukin-4 signaling pathway (ISO)

Jak-Stat signaling pathway (IEA)

measles pathway (IEA)

primary immunodeficiency pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal adaptive immunity (IAGP)

abnormal alpha-beta intraepithelial T cell morphology (IAGP)

abnormal B cell number (IAGP)

abnormal basophil physiology (IAGP)

abnormal CD4-positive, alpha beta T cell morphology (IAGP)

abnormal cecum morphology (IAGP)

abnormal cell-mediated immunity (IAGP)

abnormal class switch recombination (IAGP)

abnormal decidua basalis morphology (IAGP)

abnormal dendritic cell physiology (IAGP)

abnormal estrous cycle (IAGP)

abnormal gamma-delta T cell differentiation (IAGP)

abnormal glucose homeostasis (IAGP)

abnormal gut-associated lymphoid tissue morphology (IAGP)

abnormal hematopoietic system morphology/development (IAGP)

abnormal immune serum protein physiology (IAGP)

abnormal immune system cell morphology (IAGP)

abnormal immune system organ morphology (IAGP)

abnormal immune system physiology (IAGP)

abnormal immunoglobulin level (IAGP)

abnormal innate immunity (IAGP)

abnormal interferon secretion (IAGP)

abnormal interleukin secretion (IAGP)

abnormal leukocyte morphology (IAGP)

abnormal lymphocyte morphology (IAGP)

abnormal mast cell physiology (IAGP)

abnormal maternal decidual layer morphology (IAGP)

abnormal mesenteric lymph node morphology (IAGP)

abnormal myelopoiesis (IAGP)

abnormal placenta metrial gland morphology (IAGP)

abnormal proerythroblast morphology (IAGP)

abnormal response to transplant (IAGP)

abnormal spleen B cell follicle morphology (IAGP)

abnormal spleen morphology (IAGP)

abnormal splenic cell ratio (IAGP)

abnormal thymocyte activation (IAGP)

abnormal thymus morphology (IAGP)

absent B cells (IAGP)

absent gamma-delta intraepithelial T cell (IAGP)

absent gamma-delta T cells (IAGP)

absent NK cells (IAGP)

absent NK T cells (IAGP)

absent peripheral lymph nodes (IAGP)

absent Peyer's patches (IAGP)

absent spleen germinal center (IAGP)

absent spleen white pulp (IAGP)

absent T cells (IAGP)

absent thymus cortex (IAGP)

absent thymus medulla (IAGP)

absent uterine NK cells (IAGP)

arrested B cell differentiation (IAGP)

arrested T cell differentiation (IAGP)

cecum inflammation (IAGP)

decreased CD4-positive, alpha-beta T cell number (IAGP)

decreased CD8-positive, alpha-beta T cell number (IAGP)

decreased double-negative T cell number (IAGP)

decreased double-positive T cell number (IAGP)

decreased IgE level (IAGP)

decreased IgG level (IAGP)

decreased IgG3 level (IAGP)

decreased IgM level (IAGP)

decreased immature B cell number (IAGP)

decreased immunoglobulin level (IAGP)

decreased incidence of tumors by ionizing radiation induction (IAGP)

decreased interferon-gamma secretion (IAGP)

decreased interleukin-2 secretion (IAGP)

decreased interleukin-4 secretion (IAGP)

decreased leukocyte cell number (IAGP)

decreased lymphocyte cell number (IAGP)

decreased macrophage cell number (IAGP)

decreased mature B cell number (IAGP)

decreased mean corpuscular volume (IAGP)

decreased myeloid dendritic cell number (IAGP)

decreased NK cell number (IAGP)

decreased NK T cell number (IAGP)

decreased plasma cell number (IAGP)

decreased pre-B cell number (IAGP)

decreased regulatory T cell number (IAGP)

decreased single-positive T cell number (IAGP)

decreased spleen white pulp amount (IAGP)

decreased splenocyte number (IAGP)

decreased susceptibility to graft versus host disease (IAGP)

decreased T cell number (IAGP)

decreased T cell proliferation (IAGP)

decreased thymocyte number (IAGP)

enlarged Peyer's patches (IAGP)

enlarged spleen (IAGP)

hyperglycemia (IAGP)

impaired natural killer cell mediated cytotoxicity (IAGP)

increased activated T cell number (IAGP)

increased CD8-positive, alpha-beta T cell number (IAGP)

increased cellular sensitivity to X-ray irradiation (IAGP)

increased macrophage cell number (IAGP)

increased megakaryocyte cell number (IAGP)

increased monocyte cell number (IAGP)

increased neutrophil cell number (IAGP)

increased sensitivity to induced morbidity/mortality (IAGP)

increased susceptibility to bacterial infection (IAGP)

increased susceptibility to Retroviridae infection (IAGP)

lung inflammation (IAGP)

lymph node hypoplasia (IAGP)

no abnormal phenotype detected (IAGP)

premature death (IAGP)

prolonged diestrus (IAGP)

prolonged estrous cycle (IAGP)

prolonged metestrus (IAGP)

small lymph nodes (IAGP)

small thymus (IAGP)

small thymus cortex (IAGP)

spleen hyperplasia (IAGP)

spleen hypoplasia (IAGP)

thrombocytopenia (IAGP)

thymus cortex hypoplasia (IAGP)

thymus cyst (IAGP)

thymus hyperplasia (IAGP)

thymus hypoplasia (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Screening for mutations causing X-linked severe combined immunodeficiency in the IL-2R gamma chain gene by single-strand conformation polymorphism analysis.	Clark PA, etal., Hum Genet. 1995 Oct;96(4):427-32.
2.	Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.	Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
3.	Correlation Between Relative Nasopharyngeal Virus RNA Load and Lymphocyte Count Disease Severity in Patients with COVID-19.	Liu Y, etal., Viral Immunol. 2020 Apr 10. doi: 10.1089/vim.2020.0062.
4.	Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases.	Mashimo T, etal., PLoS One. 2010 Jan 25;5(1):e8870.
5.	MGDs mouse GO annotations	MGD data from the GO Consortium
6.	MGD IEA	MGD IEA
7.	Generation of immunodeficient rats with Rag1 and Il2rg gene deletions and human tissue grafting models.	Ménoret S, etal., Transplantation. 2018 Apr 24. doi: 10.1097/TP.0000000000002251.
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
10.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
12.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

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PMID:25733518	PMID:25769613	PMID:25794782	PMID:25818301	PMID:25834108	PMID:25838284	PMID:25849135	PMID:25870199	PMID:25902484	PMID:25908435	PMID:25915732	PMID:25939063
PMID:25964370	PMID:25964371	PMID:26022250	PMID:26039259	PMID:26113085	PMID:26181057	PMID:26214742	PMID:26276629	PMID:26276631	PMID:26280998	PMID:26286024	PMID:26316789
PMID:26320660	PMID:26321222	PMID:26338970	PMID:26403887	PMID:26424750	PMID:26429886	PMID:26439188	PMID:26542681	PMID:26546129	PMID:26569593	PMID:26595887	PMID:26595889
PMID:26603207	PMID:26644351	PMID:26675347	PMID:26675736	PMID:26678340	PMID:26690701	PMID:26702062	PMID:26744522	PMID:26752157	PMID:26755706	PMID:26785948	PMID:26787820
PMID:26796361	PMID:26809508	PMID:26831077	PMID:26847546	PMID:26849055	PMID:26863197	PMID:26879149	PMID:26884167	PMID:26886799	PMID:27010363	PMID:27064285	PMID:27099312
PMID:27139822	PMID:27158907	PMID:27184849	PMID:27197203	PMID:27197263	PMID:27256700	PMID:27292632	PMID:27300437	PMID:27307565	PMID:27323875	PMID:27373157	PMID:27438770
PMID:27478039	PMID:27496730	PMID:27499200	PMID:27521341	PMID:27535619	PMID:27545889	PMID:27564380	PMID:27581357	PMID:27622331	PMID:27634757	PMID:27671674	PMID:27698445
PMID:27699249	PMID:27705792	PMID:27708334	PMID:27723723	PMID:27752043	PMID:27783956	PMID:27856754	PMID:27872496	PMID:27905395	PMID:28069805	PMID:28077418	PMID:28087712
PMID:28089909	PMID:28108611	PMID:28111009	PMID:28115719	PMID:28264908	PMID:28331303	PMID:28424516	PMID:28426964	PMID:28512240	PMID:28561023	PMID:28585539	PMID:28591638
PMID:28606987	PMID:28617827	PMID:28665271	PMID:28678791	PMID:28698286	PMID:28715505	PMID:28727820	PMID:28747424	PMID:28783663	PMID:28783664	PMID:28814715	PMID:28827518
PMID:28844693	PMID:28869974	PMID:28874533	PMID:28945245	PMID:28959975	PMID:28960205	PMID:28963568	PMID:29032169	PMID:29056343	PMID:29070650	PMID:29136504	PMID:29146734
PMID:29150564	PMID:29150659	PMID:29151581	PMID:29159199	PMID:29166590	PMID:29183988	PMID:29222435	PMID:29266841	PMID:29287229	PMID:29290617	PMID:29298866	PMID:29334357
PMID:29361613	PMID:29387068	PMID:29396470	PMID:29409495	PMID:29429633	PMID:29446074	PMID:29474906	PMID:29496881	PMID:29533787	PMID:29540197	PMID:29549333	PMID:29551267
PMID:29559473	PMID:29594927	PMID:29624673	PMID:29700358	PMID:29719266	PMID:29720662	PMID:29725010	PMID:29858012	PMID:29861285	PMID:29894694	PMID:29910151	PMID:29915428
PMID:29925696	PMID:29942093	PMID:29950446	PMID:29975766	PMID:30010246	PMID:30021144	PMID:30049704	PMID:30065364	PMID:30134157	PMID:30154103	PMID:30174304	PMID:30258450
PMID:30352428	PMID:30383447	PMID:30487575	PMID:30504915	PMID:30540841	PMID:30590049	PMID:30651344	PMID:30664659	PMID:30679796	PMID:30720218	PMID:30778347	PMID:30800133
PMID:30883740	PMID:30888052	PMID:30894377	PMID:30936486	PMID:30943405	PMID:31091443	PMID:31103381	PMID:31127091	PMID:31160568	PMID:31171792	PMID:31185213	PMID:31230747
PMID:31269440	PMID:31341106	PMID:31353223	PMID:31371796	PMID:31375314	PMID:31378988	PMID:31415243	PMID:31434684	PMID:31515941	PMID:31534216	PMID:31537642	PMID:31558757
PMID:31609965	PMID:31672934	PMID:31745215	PMID:31758089	PMID:31772172	PMID:31810881	PMID:31852888	PMID:31873294	PMID:31913286	PMID:31915293	PMID:31982409	PMID:32075728
PMID:32101749	PMID:32130954	PMID:32144163	PMID:32213588	PMID:32381589	PMID:32484802	PMID:32522871	PMID:32632165	PMID:32730753	PMID:32735605	PMID:32763164	PMID:32768387
PMID:32814902	PMID:32817334	PMID:32817844	PMID:32884084	PMID:32949466	PMID:32968282	PMID:33027513	PMID:33087935	PMID:33097708	PMID:33104171	PMID:33119032	PMID:33125370
PMID:33177175	PMID:33253759	PMID:33295943	PMID:33305354	PMID:33373620	PMID:33428661	PMID:33536623	PMID:33724364	PMID:33929319	PMID:33951431	PMID:34010296	PMID:34133926
PMID:34289373	PMID:34303658	PMID:34326208	PMID:34388391	PMID:34429328	PMID:34437840	PMID:34555336	PMID:34813502	PMID:34848557	PMID:34961794	PMID:34971407	PMID:35039332
PMID:35075279	PMID:35089323	PMID:35090595	PMID:35145162	PMID:35444206	PMID:35550508	PMID:35587733	PMID:35709757	PMID:36044899	PMID:36045118	PMID:36211388	PMID:36352193
PMID:36476935

Genomics

Comparative Map Data

Il2rg
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	100,307,991 - 100,311,861 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	100,307,984 - 100,311,861 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	101,264,385 - 101,268,255 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	101,264,378 - 101,268,255 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	98,459,726 - 98,463,545 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	97,467,106 - 97,470,925 (-)	NCBI		MGSCv36	mm8
Celera	X	88,180,558 - 88,184,377 (-)	NCBI		Celera
Cytogenetic Map	X	D	NCBI
cM Map	X	43.9	NCBI

IL2RG
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	71,107,404 - 71,111,577 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	X	71,107,404 - 71,112,108 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	70,327,254 - 70,331,427 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	70,243,984 - 70,248,128 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	70,110,279 - 70,114,424	NCBI
Celera	X	70,681,159 - 70,685,386 (-)	NCBI		Celera
Cytogenetic Map	X	q13.1	NCBI
HuRef	X	64,146,973 - 64,150,762 (-)	NCBI		HuRef
CHM1_1	X	70,219,589 - 70,223,820 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	69,541,496 - 69,545,673 (-)	NCBI		T2T-CHM13v2.0

Il2rg
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	66,395,330 - 66,399,026 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	66,392,542 - 66,399,823 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	67,878,691 - 67,882,351 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	X	71,379,079 - 71,382,739 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	X	68,939,986 - 68,943,646 (-)	NCBI	Rnor_WKY
Rnor_6.0	X	71,165,378 - 71,169,078 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	71,162,585 - 71,169,865 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	72,017,856 - 72,021,516 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	89,342,055 - 89,345,715 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	89,416,495 - 89,419,068 (-)	NCBI
Celera	X	66,751,239 - 66,754,899 (-)	NCBI		Celera
Cytogenetic Map	X	q22	NCBI

Il2rg
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955475	10,676,870 - 10,680,517 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955475	10,676,592 - 10,680,565 (-)	NCBI	ChiLan1.0	ChiLan1.0

IL2RG
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	X	70,433,355 - 70,437,590 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	70,433,360 - 70,437,590 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	X	60,375,815 - 60,386,936 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

IL2RG
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	55,480,846 - 55,488,485 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	55,481,092 - 55,484,751 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	46,308,162 - 46,311,760 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	56,449,759 - 56,453,658 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	56,450,007 - 56,453,637 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	54,418,234 - 54,421,830 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	55,749,655 - 55,753,253 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	55,676,806 - 55,680,404 (-)	NCBI		UU_Cfam_GSD_1.0
Dog Cytomap	X	q	NCBI

Il2rg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	46,725,215 - 46,728,870 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936762	487,380 - 491,044 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936762	487,414 - 491,028 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL2RG
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	57,143,570 - 57,147,256 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	57,143,568 - 57,151,242 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	64,674,048 - 64,677,372 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Pig Cytomap	X	q13	NCBI

IL2RG
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	60,905,011 - 60,915,723 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	60,905,343 - 60,909,149 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	2,765,485 - 2,776,292 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Il2rg
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624903	1,402,481 - 1,406,600 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624903	1,402,586 - 1,406,554 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	899
Count of miRNA genes:	537
Interacting mature miRNAs:	620
Transcripts:	ENSMUST00000033664, ENSMUST00000127538, ENSMUST00000135038, ENSMUST00000145074
Prediction methods:	Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357433	Dbts2_m	diabetes 2 (mouse)			Not determined		X	7226295	150107038	Mouse
4141630	Gct6_m	granulosa cell tumorigenesis 6 (mouse)			Not determined			47179121	129764756	Mouse
13824980	Ferq1_m	genetic fertility QTL 1 (mouse)					X	54045360	148782996	Mouse
4141665	Mhysq2_m	male hybrid sterility QTL 2 (mouse)			Not determined			71453852	139203212	Mouse
12879918	Shm4_m	sperm head morphology 4 (mouse)					X	72072050	102062720	Mouse
1357500	Mdmsc6_m	modifier of muscularity 6 (mouse)			Not determined		X	75306671	109306758	Mouse
1302054	Gct4_m	granulosa cell tumorigenesis 4 (mouse)			Not determined		X	76124336	102062720	Mouse
11075102	Modc2_m	modifier of Odc2 (mouse)					X	80189914	114190059	Mouse
4141803	Lmr30_m	leishmaniasis resistance 30 (mouse)			Not determined			85062606	119062720	Mouse
13208552	Wght12_m	weight 12 (mouse)					X	94043606	149782996	Mouse
13208556	Lgth14_m	body length 14 (mouse)					X	94043606	149782996	Mouse

Markers in Region

D13565

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	101,264,730 - 101,264,810	UniSTS	GRCm38
MGSCv37	X	98,460,069 - 98,460,149	UniSTS	GRCm37
Celera	X	88,180,901 - 88,180,981	UniSTS
Cytogenetic Map	X	D	UniSTS
cM Map	X	38.0	UniSTS
Whitehead/MRC_RH	X	1117.13	UniSTS

U21795

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	101,264,625 - 101,264,800	UniSTS	GRCm38
MGSCv37	X	98,459,964 - 98,460,139	UniSTS	GRCm37
Celera	X	88,180,796 - 88,180,971	UniSTS
Cytogenetic Map	X	D	UniSTS
cM Map	X	38.0	UniSTS
Whitehead/MRC_RH	X	1117.13	UniSTS
Whitehead_YAC	X		UniSTS

PMC155645P2

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	101,266,307 - 101,267,016	UniSTS	GRCm38
MGSCv37	X	98,461,646 - 98,462,355	UniSTS	GRCm37
Celera	X	88,182,478 - 88,183,187	UniSTS
Cytogenetic Map	X	D	UniSTS
cM Map	X	38.0	UniSTS

Il2rg

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	101,264,987 - 101,265,433	UniSTS	GRCm38
MGSCv37	X	98,460,326 - 98,460,772	UniSTS	GRCm37
Celera	X	88,181,158 - 88,181,604	UniSTS
Cytogenetic Map	X	D	UniSTS
cM Map	X	38.0	UniSTS

Il2rg

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	101,266,264 - 101,267,811	UniSTS	GRCm38
MGSCv37	X	98,461,603 - 98,463,150	UniSTS	GRCm37
Celera	X	88,182,435 - 88,183,982	UniSTS
Cytogenetic Map	X	D	UniSTS

Il2rg

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	X	D	UniSTS

U21795

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	X	101,264,316 - 101,264,462	UniSTS	GRCm38
MGSCv37	X	98,459,655 - 98,459,801	UniSTS	GRCm37
Celera	X	88,180,487 - 88,180,633	UniSTS
Cytogenetic Map	X	D	UniSTS
Whitehead/MRC_RH	X	1117.13	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001308535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_013563	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017318396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AH004671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK143669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK153873	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL683892	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC014720	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D13565	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D13821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KC815469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L20048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U21795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X75337	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000033664 ⟹ ENSMUSP00000033664

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	X	100,307,984 - 100,311,861 (-)	Ensembl
GRCm38.p6 Ensembl	X	101,264,378 - 101,268,255 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000127538

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	X	100,310,802 - 100,311,764 (-)	Ensembl
GRCm38.p6 Ensembl	X	101,267,196 - 101,268,158 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000135038 ⟹ ENSMUSP00000123318

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	X	100,308,544 - 100,311,040 (-)	Ensembl
GRCm38.p6 Ensembl	X	101,264,938 - 101,267,434 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000145074

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	X	100,310,272 - 100,311,796 (-)	Ensembl
GRCm38.p6 Ensembl	X	101,266,666 - 101,268,190 (-)	Ensembl

RefSeq Acc Id:

NM_001308535 ⟹ NP_001295464

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	100,307,991 - 100,311,861 (-)	NCBI
GRCm38	X	101,264,385 - 101,268,255 (-)	NCBI

Sequence:

show sequence

AGGAAATGTATGGGTGGGGAGGGCTTGTGGGAGAGTGGTTCAGGGTTCTGACACAGACTACACC
CAGAGAAAGAAGAGCAAGCACCATGTTGAAACTATTATTGTCACCTAGATCCTTCTTAGTCCTT
CAGCTGCTCCTGCTGAGGGCAGGGTGGAGCTCCAAGGTCCTCATGTCCAGTGCGAATGAAGACA
TCAAAGCTGATTTGATCCTGACTTCTACAGCCCCTGAACACCTCAGTGCTCCTACTCTGCCCCT
TCCAGAGGTTCAGTGCTTTGTGTTCAACATAGAGTACATGAATTGCACTTGGAATAGCAGTTCT
GAGCCTCAGGCAACCAACCTCACGCTGCACTATAGGTACAAGGTATCTGATAATAATACATTCC
AGGAGTGCAGTCACTATTTGTTCTCCAAAGAGATTACTTCTGGCTGTCAGATACAAAAAGAAGA
TATCCAGCTCTACCAGACATTTGTTGTCCAGCTCCAGGACCCCCAGAAACCCCAGAGGCGAGCT
GTACAGAAGCTAAACCTACAGAATCTTGTGATCCCACGGGCTCCAGAAAATCTAACACTCAGCA
ATCTGAGTGAATCCCAGCTAGAGCTGAGATGGAAAAGCAGACATATTAAAGAACGCTGTTTACA
ATACTTGGTGCAGTACCGGAGCAACAGAGATCGAAGCTGGACGGAACTAATAGTGAATCATGAA
CCTAGATTCTCCCTGCCTAGTGTGGATGAGCTGAAACGAGAATCCTTCCTTGTTTGCACTGGAA
GCTGTGCTTATCCCTGTTGGCACCATGGGGTTGATTATTACCCTGATCTTTGTGTACTGTTGGT
TGGAACGAATGCCTCCAATTCCCCCCATCAAGAATCTAGAGGATCTGGTTACTGAATACCAAGG
GAACTTTTCGGCCTGGAGTGGTGTGTCTAAAGGGCTGACTGAGAGTCTGCAGCCAGACTACAGT
GAACGGTTCTGCCACGTCAGCGAGATTCCCCCCAAAGGAGGGGCCCTAGGAGAGGGGCCTGGAG
GTTCTCCTTGCAGCCTGCATAGCCCTTACTGGCCTCCCCCATGTTATTCTCTGAAGCCGGAAGC
CTGAACATCAATCCTTTGATGGAACCTCAAAGTCCTATAGTCCTAAGTGACGCTAACCTCCCCT
ACTCACCTTGGCAATCTGGATCCAATGCTCACTGCCTTCCCTTGGGGCTAAGTTTCGATTTCCT
GTCCCATGTAACTGCTTTTCTGTTCCATATGCCCTACTTGAGAGTGTCCCTTGCCCTCTTTCCC
TGCACAAGCCCTCCCATGCCCAGCCTAACACCTTTCCACTTTCTTTGAAGAGAGTCTTACCCTG
TAGCCCAGGGTGGCTGGGAGCTCACTATGTAGGCCAGGTTGGCCTCCAACTCACAGGCTATCCT
CCCACCTCTGCCTCATAAGAGTTGGGGTTACTGGCATGCACCACCACACCCAGCATGGTCCTTC
TCTTTTATAGGATTCTCCCTCCCTTTTTCTACCTATGATTCAACTGTTTCCAAATCAACAAGAA
ATAAAGTTTTTAACCAATGATCA

hide sequence

RefSeq Acc Id:

NM_013563 ⟹ NP_038591

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	100,307,991 - 100,311,861 (-)	NCBI
GRCm38	X	101,264,385 - 101,268,255 (-)	NCBI
MGSCv37	X	98,459,726 - 98,463,545 (-)	RGD
Celera	X	88,180,558 - 88,184,377 (-)	RGD
cM Map	X		ENTREZGENE

Sequence:

show sequence

AGGAAATGTATGGGTGGGGAGGGCTTGTGGGAGAGTGGTTCAGGGTTCTGACACAGACTACACC
CAGAGAAAGAAGAGCAAGCACCATGTTGAAACTATTATTGTCACCTAGATCCTTCTTAGTCCTT
CAGCTGCTCCTGCTGAGGGCAGGGTGGAGCTCCAAGGTCCTCATGTCCAGTGCGAATGAAGACA
TCAAAGCTGATTTGATCCTGACTTCTACAGCCCCTGAACACCTCAGTGCTCCTACTCTGCCCCT
TCCAGAGGTTCAGTGCTTTGTGTTCAACATAGAGTACATGAATTGCACTTGGAATAGCAGTTCT
GAGCCTCAGGCAACCAACCTCACGCTGCACTATAGGTACAAGGTATCTGATAATAATACATTCC
AGGAGTGCAGTCACTATTTGTTCTCCAAAGAGATTACTTCTGGCTGTCAGATACAAAAAGAAGA
TATCCAGCTCTACCAGACATTTGTTGTCCAGCTCCAGGACCCCCAGAAACCCCAGAGGCGAGCT
GTACAGAAGCTAAACCTACAGAATCTTGTGATCCCACGGGCTCCAGAAAATCTAACACTCAGCA
ATCTGAGTGAATCCCAGCTAGAGCTGAGATGGAAAAGCAGACATATTAAAGAACGCTGTTTACA
ATACTTGGTGCAGTACCGGAGCAACAGAGATCGAAGCTGGACGGAACTAATAGTGAATCATGAA
CCTAGATTCTCCCTGCCTAGTGTGGATGAGCTGAAACGGTACACATTTCGGGTTCGGAGCCGCT
ATAACCCAATCTGTGGAAGTTCTCAACAGTGGAGTAAATGGAGCCAGCCTGTCCACTGGGGGAG
TCATACTGTAGAGGAGAATCCTTCCTTGTTTGCACTGGAAGCTGTGCTTATCCCTGTTGGCACC
ATGGGGTTGATTATTACCCTGATCTTTGTGTACTGTTGGTTGGAACGAATGCCTCCAATTCCCC
CCATCAAGAATCTAGAGGATCTGGTTACTGAATACCAAGGGAACTTTTCGGCCTGGAGTGGTGT
GTCTAAAGGGCTGACTGAGAGTCTGCAGCCAGACTACAGTGAACGGTTCTGCCACGTCAGCGAG
ATTCCCCCCAAAGGAGGGGCCCTAGGAGAGGGGCCTGGAGGTTCTCCTTGCAGCCTGCATAGCC
CTTACTGGCCTCCCCCATGTTATTCTCTGAAGCCGGAAGCCTGAACATCAATCCTTTGATGGAA
CCTCAAAGTCCTATAGTCCTAAGTGACGCTAACCTCCCCTACTCACCTTGGCAATCTGGATCCA
ATGCTCACTGCCTTCCCTTGGGGCTAAGTTTCGATTTCCTGTCCCATGTAACTGCTTTTCTGTT
CCATATGCCCTACTTGAGAGTGTCCCTTGCCCTCTTTCCCTGCACAAGCCCTCCCATGCCCAGC
CTAACACCTTTCCACTTTCTTTGAAGAGAGTCTTACCCTGTAGCCCAGGGTGGCTGGGAGCTCA
CTATGTAGGCCAGGTTGGCCTCCAACTCACAGGCTATCCTCCCACCTCTGCCTCATAAGAGTTG
GGGTTACTGGCATGCACCACCACACCCAGCATGGTCCTTCTCTTTTATAGGATTCTCCCTCCCT
TTTTCTACCTATGATTCAACTGTTTCCAAATCAACAAGAAATAAAGTTTTTAACCAATGATCA

hide sequence

RefSeq Acc Id:

XM_017318396 ⟹ XP_017173885

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	X	100,308,544 - 100,311,856 (-)	NCBI
GRCm38	X	101,264,387 - 101,268,251 (-)	NCBI

Sequence:

show sequence

ATGTATGGGTGGGGAGGGCTTGTGGGAGAGTGGTTCAGGGTTCTGACACAGACTACACCCAGAG
AAAGAAGAGCAAGCACCATGTTGAAACTATTATTGTCACCTAGATCCTTCTTAGTCCTTCAGCT
GCTCCTGCTGAGGGCAGGGTGGAGCTCCAAGGTCCTCATGTCCAGTGCGAATGAAGACATCAAA
GCTGATTTGATCCTGACTTCTACAGCCCCTGAACACCTCAGTGCTCCTACTCTGCCCCTTCCAG
AGGTTCAGTGCTTTGTGTTCAACATAGAGTACATGAATTGCACTTGGAATAGCAGTTCTGAGCC
TCAGGCAACCAACCTCACGCTGCACTATAGGTACAAGGTATCTGATAATAATACATTCCAGGAG
TGCAGTCACTATTTGTTCTCCAAAGAGATTACTTCTGGCTGTCAGATACAAAAAGAAGATATCC
AGCTCTACCAGACATTTGTTGTCCAGCTCCAGGACCCCCAGAAACCCCAGAGGCGAGCTGTACA
GAAGCTAAACCTACAGAATCTTGTGATCCCACGGGCTCCAGAAAATCTAACACTCAGCAATCTG
AGTGAATCCCAGCTAGAGCTGAGATGGAAAAGCAGACATATTAAAGAACGCTGTTTACAATACT
TGGTGCAGTACCGGAGCAACAGAGATCGAAGCTGGACGGAACTAATAGTGAATCATGAACCTAG
ATTCTCCCTGCCTAGTGTGGATGAGCTGAAACGGTACACATTTCGGGTTCGGAGCCGCTATAAC
CCAATCTGTGGAAGTTCTCAACAGTGGAGTAAATGGAGCCAGCCTGTCCACTGGGGGAGTCATA
CTGTAGAGGAATGCCTCCAATTCCCCCCATCAAGAATCTAGAGGATCTGGTTACTGAATACCAA
GGGAACTTTTCGGCCTGGAGTGGTGTGTCTAAAGGGCTGACTGAGAGTCTGCAGCCAGACTACA
GTGAACGGTTCTGCCACGTCAGCGAGATTCCCCCCAAAGGAGGGGCCC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001295464	(Get FASTA)	NCBI Sequence Viewer
	NP_038591	(Get FASTA)	NCBI Sequence Viewer
	XP_017173885	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA39286	(Get FASTA)	NCBI Sequence Viewer
	AAA64279	(Get FASTA)	NCBI Sequence Viewer
	AAB32904	(Get FASTA)	NCBI Sequence Viewer
	AAH14720	(Get FASTA)	NCBI Sequence Viewer
	AHB51068	(Get FASTA)	NCBI Sequence Viewer
	BAA02760	(Get FASTA)	NCBI Sequence Viewer
	BAA02974	(Get FASTA)	NCBI Sequence Viewer
	BAE25487	(Get FASTA)	NCBI Sequence Viewer
	CAA53085	(Get FASTA)	NCBI Sequence Viewer
	EDL14151	(Get FASTA)	NCBI Sequence Viewer
	EDL14152	(Get FASTA)	NCBI Sequence Viewer
	P34902	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_038591 ⟸ NM_013563
- Peptide Label:	isoform a precursor
- UniProtKB:	P34902 (UniProtKB/Swiss-Prot), Q3UPA9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLKLLLSPRSFLVLQLLLLRAGWSSKVLMSSANEDIKADLILTSTAPEHLSAPTLPLPEVQCFV FNIEYMNCTWNSSSEPQATNLTLHYRYKVSDNNTFQECSHYLFSKEITSGCQIQKEDIQLYQTF VVQLQDPQKPQRRAVQKLNLQNLVIPRAPENLTLSNLSESQLELRWKSRHIKERCLQYLVQYRS NRDRSWTELIVNHEPRFSLPSVDELKRYTFRVRSRYNPICGSSQQWSKWSQPVHWGSHTVEENP SLFALEAVLIPVGTMGLIITLIFVYCWLERMPPIPPIKNLEDLVTEYQGNFSAWSGVSKGLTES LQPDYSERFCHVSEIPPKGGALGEGPGGSPCSLHSPYWPPPCYSLKPEA hide sequence

RefSeq Acc Id:	NP_001295464 ⟸ NM_001308535
- Peptide Label:	isoform b precursor
- UniProtKB:	Q3UPA9 (UniProtKB/TrEMBL), V5SIM2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLKLLLSPRSFLVLQLLLLRAGWSSKVLMSSANEDIKADLILTSTAPEHLSAPTLPLPEVQCFV FNIEYMNCTWNSSSEPQATNLTLHYRYKVSDNNTFQECSHYLFSKEITSGCQIQKEDIQLYQTF VVQLQDPQKPQRRAVQKLNLQNLVIPRAPENLTLSNLSESQLELRWKSRHIKERCLQYLVQYRS NRDRSWTELIVNHEPRFSLPSVDELKRESFLVCTGSCAYPCWHHGVDYYPDLCVLLVGTNASNS PHQESRGSGY hide sequence

RefSeq Acc Id:

XP_017173885 ⟸ XM_017318396

- Peptide Label:

isoform X1

- Sequence:

show sequence

MYGWGGLVGEWFRVLTQTTPRERRASTMLKLLLSPRSFLVLQLLLLRAGWSSKVLMSSANEDIK
ADLILTSTAPEHLSAPTLPLPEVQCFVFNIEYMNCTWNSSSEPQATNLTLHYRYKVSDNNTFQE
CSHYLFSKEITSGCQIQKEDIQLYQTFVVQLQDPQKPQRRAVQKLNLQNLVIPRAPENLTLSNL
SESQLELRWKSRHIKERCLQYLVQYRSNRDRSWTELIVNHEPRFSLPSVDELKRYTFRVRSRYN
PICGSSQQWSKWSQPVHWGSHTVEECLQFPPSRI

hide sequence

RefSeq Acc Id:

ENSMUSP00000033664 ⟸ ENSMUST00000033664

RefSeq Acc Id:

ENSMUSP00000123318 ⟸ ENSMUST00000135038

Protein Domains

Fibronectin type-III Type I cytokine receptor cytokine-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P34902-F1-model_v2	AlphaFold	P34902	1-369	view protein structure

Promoters

RGD ID:

6845860

Promoter ID:

MM_KWN:61304

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_2Hour, BoneMarrow_4Hour, Lung

Transcripts:

OTTMUST00000043981

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	X	98,462,331 - 98,463,372 (-)	MPROMDB

RGD ID:

6845862

Promoter ID:

MM_KWN:61305

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Spleen

Transcripts:

OTTMUST00000043978, OTTMUST00000043980, UC009TXD.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	X	98,463,431 - 98,464,162 (-)	MPROMDB

RGD ID:

13681062

Promoter ID:

EPDNEW_M24680

Type:

initiation region

Name:

Il2rg_1

Description:

Mus musculus interleukin 2 receptor, gamma chain , transcriptvariant b, mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	X	101,268,201 - 101,268,261	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:96551	AgrOrtholog
Ensembl Genes	ENSMUSG00000031304	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000033664	ENTREZGENE
	ENSMUSP00000033664.8	UniProtKB/Swiss-Prot
	ENSMUSP00000123318.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000033664	ENTREZGENE
	ENSMUST00000033664.14	UniProtKB/Swiss-Prot
	ENSMUST00000135038.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	FN3_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FN3_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Hempt_rcpt_S_F1_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TypeI_recpt_CBD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:16186	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:96551	ENTREZGENE
NCBI Gene	16186	ENTREZGENE
PANTHER	CYTOKINE RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	INTERLEUKIN 2 RECEPTOR GAMMA COMMON.B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	fn3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	IL6Ra-bind	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Il2rg	PhenoGen
PROSITE	FN3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HEMATOPO_REC_S_F1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	FN3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF49265	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	B0QZX1_MOUSE	UniProtKB/TrEMBL
	IL2RG_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q3UPA9	ENTREZGENE, UniProtKB/TrEMBL
	V5SIM2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

Mammalian Phenotype

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Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

Mammalian Phenotype