Polr1b (polymerase (RNA) I polypeptide B) - Rat Genome Database

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Gene: Polr1b (polymerase (RNA) I polypeptide B) Mus musculus
Analyze
Symbol: Polr1b
Name: polymerase (RNA) I polypeptide B
RGD ID: 731265
MGI Page MGI
Description: Predicted to enable DNA-directed 5'-3' RNA polymerase activity; DNA/RNA hybrid binding activity; and zinc ion binding activity. Predicted to contribute to RNA polymerase I activity. Acts upstream of or within embryo implantation; nucleologenesis; and rRNA transcription. Located in chromosome and nucleolus. Part of RNA polymerase I complex. Is expressed in several structures, including alimentary system; central nervous system; heart; integumental system; and respiratory system. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 4. Orthologous to human POLR1B (RNA polymerase I subunit B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 128kD; 128kDa; D630020H17Rik; DNA-directed RNA polymerase I 135 kDa polypeptide; DNA-directed RNA polymerase I 135kDa polypeptide; DNA-directed RNA polymerase I subunit RPA2; R; RNA polymerase 1-2, 128 kDa subunit; RNA polymerase I subunit 2; RPA; RPA116; RPA135; RPA2; Rpo; Rpo1-2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392128,942,891 - 128,969,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2128,942,915 - 128,968,514 (+)EnsemblGRCm39 Ensembl
GRCm382129,100,970 - 129,128,060 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,100,995 - 129,126,594 (+)EnsemblGRCm38mm10GRCm38
MGSCv372128,926,732 - 128,952,331 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362128,792,479 - 128,818,036 (+)NCBIMGSCv36mm8
Celera2130,328,366 - 130,353,838 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-alpha-phellandrene  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-hexachlorocyclohexane  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (EXP)
chlorpyrifos  (EXP)
chromium(6+)  (EXP)
copper(II) sulfate  (ISO)
cordycepin  (EXP)
coumestrol  (ISO)
DDE  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
formaldehyde  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
Indeno[1,2,3-cd]pyrene  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
maneb  (EXP)
methotrexate  (EXP,ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nitroglycerin  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetraphene  (EXP)
theophylline  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
Tributyltin oxide  (EXP)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation. Schneider DA Gene. 2012 Feb 10;493(2):176-84. doi: 10.1016/j.gene.2011.08.006. Epub 2011 Aug 26.
9. Molecular cloning of RPA2, the gene encoding the second largest subunit of mouse RNA polymerase I. Seither P and Grummt I, Genomics 1996 Oct 1;37(1):135-9.
10. Conservation between the RNA polymerase I, II, and III transcription initiation machineries. Vannini A and Cramer P, Mol Cell. 2012 Feb 24;45(4):439-46. doi: 10.1016/j.molcel.2012.01.023.
Additional References at PubMed
PMID:9236775   PMID:10349636   PMID:10512203   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11592397   PMID:12393749   PMID:12477932   PMID:12904583   PMID:14610273  
PMID:14681479   PMID:15004009   PMID:15558034   PMID:15782199   PMID:15805466   PMID:15989966   PMID:16033648   PMID:16141072   PMID:16141073   PMID:16582105   PMID:18023416   PMID:20059953  
PMID:20211142   PMID:21059229   PMID:21873635   PMID:22403788   PMID:26206133   PMID:27480124   PMID:30272023   PMID:30746471   PMID:30949703   PMID:38355793  


Genomics

Comparative Map Data
Polr1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392128,942,891 - 128,969,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2128,942,915 - 128,968,514 (+)EnsemblGRCm39 Ensembl
GRCm382129,100,970 - 129,128,060 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,100,995 - 129,126,594 (+)EnsemblGRCm38mm10GRCm38
MGSCv372128,926,732 - 128,952,331 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362128,792,479 - 128,818,036 (+)NCBIMGSCv36mm8
Celera2130,328,366 - 130,353,838 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map262.68NCBI
POLR1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382112,542,036 - 112,579,818 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2112,541,915 - 112,579,818 (+)EnsemblGRCh38hg38GRCh38
GRCh372113,299,613 - 113,337,395 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,016,084 - 113,051,879 (+)NCBINCBI36Build 36hg18NCBI36
Build 342113,015,843 - 113,051,639NCBI
Celera2106,685,049 - 106,720,277 (+)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2105,754,007 - 105,789,231 (+)NCBIHuRef
CHM1_12113,303,652 - 113,338,870 (+)NCBICHM1_1
T2T-CHM13v2.02112,968,686 - 113,006,450 (+)NCBIT2T-CHM13v2.0
Polr1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83136,787,130 - 136,811,608 (+)NCBIGRCr8
mRatBN7.23116,333,910 - 116,358,385 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,333,889 - 116,358,379 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,231,013 - 120,255,438 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03128,826,598 - 128,851,016 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03126,487,078 - 126,511,500 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03121,632,043 - 121,656,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3121,632,043 - 121,656,506 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03128,358,264 - 128,382,727 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43116,706,483 - 116,730,946 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13116,612,055 - 116,636,519 (+)NCBI
Celera3115,159,305 - 115,183,765 (+)NCBICelera
Cytogenetic Map3q36NCBI
Polr1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,714,156 - 1,737,820 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,714,156 - 1,737,749 (-)NCBIChiLan1.0ChiLan1.0
POLR1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21215,545,294 - 15,588,412 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A15,548,058 - 15,584,608 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A89,478,133 - 89,516,559 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A113,555,452 - 113,590,377 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A113,555,452 - 113,590,377 (+)Ensemblpanpan1.1panPan2
POLR1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11736,774,472 - 36,798,900 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1736,774,541 - 36,797,525 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,543,712 - 36,568,761 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01737,550,047 - 37,575,002 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1737,545,667 - 37,575,002 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11736,688,159 - 36,713,214 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01736,742,224 - 36,767,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01736,956,099 - 36,980,996 (+)NCBIUU_Cfam_GSD_1.0
Polr1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,139,613 - 82,161,453 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367831,034,054 - 1,056,384 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367831,034,097 - 1,055,798 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POLR1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl343,950,002 - 43,975,683 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1343,949,032 - 43,974,283 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2345,544,060 - 45,568,445 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POLR1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11415,549,963 - 15,585,947 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1415,550,254 - 15,584,521 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660804,095,537 - 4,131,082 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Polr1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474912,602,004 - 12,625,200 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474912,602,078 - 12,625,200 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Polr1b
656 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:670
Count of miRNA genes:461
Interacting mature miRNAs:532
Transcripts:ENSMUST00000028874, ENSMUST00000103205, ENSMUST00000133345, ENSMUST00000144004, ENSMUST00000147727
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
13506763Tbvq1_mtrabecular bone volume QTL 1 (mouse)2126041920135441920Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1301066Otx2m2_morthodenticle homolog 2 (Drosophila) modifier 2 (mouse)Not determined2123231973148700377Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
1558989Gnf4_mgrowth and fatness 4 (mouse)Not determined2128173704132714157Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1300712El2_mepilepsy 2 (mouse)Not determined2122207146142532135Mouse

Markers in Region
Rpo1-2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2F3UniSTS
cM Map2 UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS


Sequence


Ensembl Acc Id: ENSMUST00000028874   ⟹   ENSMUSP00000028874
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2128,942,947 - 128,962,688 (+)Ensembl
GRCm38.p6 Ensembl2129,101,027 - 129,120,768 (+)Ensembl
Ensembl Acc Id: ENSMUST00000103205   ⟹   ENSMUSP00000099494
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2128,942,915 - 128,968,514 (+)Ensembl
GRCm38.p6 Ensembl2129,100,995 - 129,126,594 (+)Ensembl
Ensembl Acc Id: ENSMUST00000133345
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2128,957,592 - 128,960,409 (+)Ensembl
GRCm38.p6 Ensembl2129,115,672 - 129,118,489 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144004
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2128,960,574 - 128,965,058 (+)Ensembl
GRCm38.p6 Ensembl2129,118,654 - 129,123,138 (+)Ensembl
Ensembl Acc Id: ENSMUST00000147727
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2128,963,631 - 128,965,758 (+)Ensembl
GRCm38.p6 Ensembl2129,121,711 - 129,123,838 (+)Ensembl
RefSeq Acc Id: NM_009086   ⟹   NP_033112
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392128,942,916 - 128,968,515 (+)NCBI
GRCm382129,100,996 - 129,126,595 (+)NCBI
MGSCv372128,926,732 - 128,952,331 (+)RGD
Celera2130,328,366 - 130,353,838 (+)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006499025   ⟹   XP_006499088
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392128,942,892 - 128,969,980 (+)NCBI
GRCm382129,100,972 - 129,128,060 (+)NCBI
Sequence:
RefSeq Acc Id: XR_374430
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392128,942,891 - 128,969,980 (+)NCBI
GRCm382129,100,970 - 129,128,060 (+)NCBI
Sequence:
RefSeq Acc Id: NP_033112   ⟸   NM_009086
- UniProtKB: Q3UMX7 (UniProtKB/Swiss-Prot),   P70700 (UniProtKB/Swiss-Prot),   Q6P9Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006499088   ⟸   XM_006499025
- Peptide Label: isoform X1
- UniProtKB: Q6P9Q2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000028874   ⟸   ENSMUST00000028874
Ensembl Acc Id: ENSMUSP00000099494   ⟸   ENSMUST00000103205
Protein Domains
DNA-directed RNA polymerase I subunit RPA2   DNA-directed RNA polymerase subunit 2 hybrid-   RNA polymerase beta subunit protrusion   RNA polymerase Rpb2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70700-F1-model_v2 AlphaFold P70700 1-1135 view protein structure

Promoters
RGD ID:6831503
Promoter ID:MM_KWN:31672
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000036591,   UC008MHF.1,   XM_001480866_GM4615
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362128,926,534 - 128,927,034 (-)MPROMDB
RGD ID:6832094
Promoter ID:MM_KWN:31673
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000036594
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362128,941,231 - 128,941,731 (+)MPROMDB
RGD ID:6878698
Promoter ID:EPDNEW_M2800
Type:initiation region
Name:Polr1b_1
Description:Mus musculus polymerase I polypeptide B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382129,101,027 - 129,101,087EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108014 AgrOrtholog
Ensembl Genes ENSMUSG00000027395 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000028874.8 UniProtKB/TrEMBL
  ENSMUST00000103205 ENTREZGENE
  ENSMUST00000103205.11 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.270.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.40.50.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1070.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.1110.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA polymerase alpha subunit dimerisation domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DNA-dir_RNA_pol_su2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA-dir_RNAP_su2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNA-dir_RNAP_su2_hyb_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_bsu_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_bsu_protrusion UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb2_2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb2_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb2_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_RPB2_OB-fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rpa2_dom_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20017 UniProtKB/Swiss-Prot
MGD MGI:108014 ENTREZGENE
NCBI Gene 20017 ENTREZGENE
PANTHER DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR20856 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RNA_pol_Rpa2_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb2_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb2_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNA_pol_Rpb2_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Polr1b PhenoGen
PROSITE RNA_POL_BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP beta and beta-prime subunits of DNA dependent RNA-polymerase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AP84_MOUSE UniProtKB/TrEMBL
  P70700 ENTREZGENE
  Q3UMX7 ENTREZGENE
  Q6P9Q2 ENTREZGENE, UniProtKB/TrEMBL
  RPA2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q3UMX7 UniProtKB/Swiss-Prot