(-)-citrinin increases expression ISO RGD:728892 6480464 Citrinin results in increased expression of E2F1 mRNA CTD PMID:23856526 (-)-epigallocatechin 3-gallate affects methylation ISO RGD:728892 6480464 epigallocatechin gallate affects the methylation of E2F1 gene CTD PMID:29381301 (25R)-cholest-5-ene-3beta,26-diol increases expression ISO RGD:730923 6480464 27-hydroxycholesterol results in increased expression of E2F1 mRNA CTD PMID:17872378 (S)-colchicine decreases expression ISO RGD:730923 6480464 Colchicine results in decreased expression of E2F1 mRNA CTD PMID:24211769 (S)-naringenin multiple interactions ISO RGD:730923 6480464 [naringenin co-treated with bisphenol A] results in increased expression of E2F1 mRNA, [naringenin metabolite co-treated with bisphenol A] results in increased expression of E2F1 mRNA CTD PMID:36235125 (S)-nicotine increases expression ISO RGD:730923 6480464 Nicotine results in increased expression of E2F1 protein CTD PMID:20061081 (S)-nicotine multiple interactions ISO RGD:730923 6480464 MK-886 inhibits the reaction [Nicotine results in increased expression of E2F1 protein] more ... CTD PMID:16601104 more ... 1,2-dimethylhydrazine increases expression EXP 6480464 1, 2-Dimethylhydrazine results in increased expression of E2F1 mRNA CTD PMID:22206623 1-chloro-2,4-dinitrobenzene affects expression EXP 6480464 Dinitrochlorobenzene affects the expression of E2F1 mRNA CTD PMID:22302311 1-naphthyl isothiocyanate increases expression ISO RGD:728892 6480464 1-Naphthylisothiocyanate results in increased expression of E2F1 mRNA CTD PMID:30723492 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of E2F1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of E2F1 mRNA CTD PMID:14976129 , PMID:17942748 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of E2F1 mRNA, Estradiol results in increased expression of E2F1 protein CTD PMID:23684557 , PMID:25210133 17beta-estradiol affects expression ISO RGD:730923 6480464 Estradiol affects the expression of E2F1 protein CTD PMID:28880708 17beta-estradiol increases activity ISO RGD:730923 6480464 Estradiol results in increased activity of E2F1 protein CTD PMID:27592001 17beta-estradiol increases expression ISO RGD:730923 6480464 Estradiol results in increased expression of E2F1 mRNA, Estradiol results in increased expression of E2F1 protein CTD PMID:14702633 more ... 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of E2F1 mRNA CTD PMID:15598610 17beta-estradiol multiple interactions ISO RGD:730923 6480464 1 more ... CTD PMID:14702633 , PMID:28880708 17beta-estradiol multiple interactions EXP 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of E2F1 mRNA] CTD PMID:25210133 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:730923 6480464 Dihydrotestosterone results in increased expression of E2F1 mRNA, Dihydrotestosterone results in increased expression of E2F1 protein CTD PMID:15647840 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:730923 6480464 2 more ... CTD PMID:26988655 , PMID:30796839 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of E2F1 mRNA CTD PMID:21570461 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:730923 6480464 Tetrachlorodibenzodioxin results in decreased expression of E2F1 mRNA, Tetrachlorodibenzodioxin results in decreased expression of E2F1 protein CTD PMID:15056799 , PMID:21802500 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of E2F1 mRNA CTD PMID:15667827 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of E2F1 mRNA CTD PMID:17942748 2-acetamidofluorene decreases expression ISO RGD:728892 6480464 2-Acetylaminofluorene results in decreased expression of E2F1 protein CTD PMID:15158336 2-acetamidofluorene increases expression ISO RGD:728892 6480464 2-Acetylaminofluorene results in increased expression of E2F1 mRNA CTD PMID:19167416 , PMID:22213190 26-hydroxycholesterol increases expression ISO RGD:730923 6480464 27-hydroxycholesterol results in increased expression of E2F1 mRNA CTD PMID:17872378 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid multiple interactions ISO RGD:730923 6480464 MK-886 inhibits the reaction [Nicotine results in increased expression of E2F1 protein] CTD PMID:20061081 3-aminobenzamide multiple interactions ISO RGD:730923 6480464 3-aminobenzamide promotes the reaction [RB1 protein binds to E2F1 protein] CTD PMID:15670817 4,4'-sulfonyldiphenol increases expression ISO RGD:730923 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of E2F1 mRNA CTD PMID:30684532 4-hydroperoxycyclophosphamide increases expression EXP 6480464 perfosfamide results in increased expression of E2F1 mRNA CTD PMID:19429390 4-hydroxynon-2-enal decreases expression ISO RGD:730923 6480464 4-hydroxy-2-nonenal results in decreased expression of E2F1 mRNA CTD PMID:12419474 4-hydroxyphenyl retinamide decreases expression EXP 6480464 Fenretinide results in decreased expression of E2F1 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of E2F1 mRNA CTD PMID:27915011 5-azacytidine multiple interactions ISO RGD:730923 6480464 E2F1 protein affects the reaction [Azacitidine results in decreased activity of TERT protein], E2F1 protein affects the reaction [Azacitidine results in decreased expression of TERT mRNA] CTD PMID:19451745 5-fluorouracil decreases expression ISO RGD:730923 6480464 Fluorouracil results in decreased expression of E2F1 mRNA CTD PMID:34151400 5-nitroso-8-quinolinol decreases expression ISO RGD:730923 6480464 5-nitroso-8-quinolinol results in decreased expression of E2F1 protein CTD PMID:16497787 5-nitroso-8-quinolinol multiple interactions ISO RGD:730923 6480464 Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of E2F1 protein] CTD PMID:16497787 6-propyl-2-thiouracil increases expression ISO RGD:728892 6480464 Propylthiouracil results in increased expression of E2F1 mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression ISO RGD:728892 6480464 Propylthiouracil results in decreased expression of E2F1 mRNA CTD PMID:25825206 acetamide increases expression ISO RGD:728892 6480464 acetamide results in increased expression of E2F1 mRNA CTD PMID:31881176 acetylsalicylic acid multiple interactions ISO RGD:730923 6480464 [troglitazone co-treated with Aspirin] results in decreased expression of E2F1 protein, Aspirin inhibits the reaction [E2F1 protein binds to BIRC5 promoter] CTD PMID:17848598 , PMID:19908241 acetylsalicylic acid decreases expression ISO RGD:730923 6480464 Aspirin results in decreased expression of E2F1 mRNA CTD PMID:20457246 acrylamide decreases expression ISO RGD:730923 6480464 Acrylamide results in decreased expression of E2F1 mRNA CTD PMID:32763439 acteoside multiple interactions ISO RGD:730923 6480464 [acteoside results in decreased phosphorylation of RB1 protein] promotes the reaction [RB1 protein binds to E2F1 protein] CTD PMID:17634406 adenine decreases expression ISO RGD:730923 6480464 Adenine results in decreased expression of E2F1 mRNA CTD PMID:24211769 aflatoxin B1 increases expression ISO RGD:730923 6480464 Aflatoxin B1 results in increased expression of E2F1 mRNA CTD PMID:15120964 aflatoxin B1 increases expression ISO RGD:728892 6480464 Aflatoxin B1 results in increased expression of E2F1 mRNA CTD PMID:23630614 , PMID:25378103 all-trans-4-oxoretinoic acid decreases expression ISO RGD:730923 6480464 4-oxoretinoic acid results in decreased expression of E2F1 mRNA CTD PMID:15982314 all-trans-retinoic acid multiple interactions ISO RGD:730923 6480464 Tretinoin inhibits the reaction [Benzo(a)pyrene results in increased expression of E2F1 protein] CTD PMID:16406622 all-trans-retinoic acid increases expression ISO RGD:730923 6480464 Tretinoin results in increased expression of E2F1 mRNA CTD PMID:17218384 all-trans-retinoic acid decreases expression ISO RGD:730923 6480464 Tretinoin metabolite results in decreased expression of E2F1 mRNA more ... CTD PMID:12042460 more ... alpha-hexylcinnamaldehyde affects expression EXP 6480464 hexyl cinnamic aldehyde affects the expression of E2F1 mRNA CTD PMID:22302311 alvocidib increases expression ISO RGD:730923 6480464 alvocidib results in increased expression of E2F1 protein CTD PMID:12533675 alvocidib increases response to substance EXP 6480464 E2F1 results in increased susceptibility to alvocidib CTD PMID:12533675 alvocidib increases response to substance ISO RGD:730923 6480464 E2F1 results in increased susceptibility to alvocidib CTD PMID:12533675 alvocidib decreases expression ISO RGD:730923 6480464 alvocidib results in decreased expression of E2F1 mRNA CTD PMID:21239698 ammonium chloride increases expression ISO RGD:728892 6480464 Ammonium Chloride results in increased expression of E2F1 protein CTD PMID:16483693 amodiaquine affects expression ISO RGD:730923 6480464 Amodiaquine affects the expression of E2F1 mRNA, Amodiaquine affects the expression of E2F1 protein CTD PMID:24113242 amphetamine decreases expression ISO RGD:728892 6480464 Amphetamine results in decreased expression of E2F1 mRNA CTD PMID:30779732 amphibole asbestos decreases expression ISO RGD:730923 6480464 Asbestos, Amphibole results in decreased expression of E2F1 protein CTD PMID:20855422 androstane multiple interactions EXP 6480464 Androstanols inhibits the reaction [1 more ... CTD PMID:26171734 aristolochic acid A increases expression ISO RGD:730923 6480464 aristolochic acid I results in increased expression of E2F1 mRNA CTD PMID:33212167 arsane multiple interactions ISO RGD:730923 6480464 E2F1 protein affects the reaction [Arsenic results in increased expression of AURKA protein] CTD PMID:23174854 arsane decreases expression ISO RGD:730923 6480464 Arsenic results in decreased expression of E2F1 mRNA CTD PMID:19945496 arsane increases expression ISO RGD:730923 6480464 Arsenic results in increased expression of E2F1 protein CTD PMID:23174854 arsenic atom decreases expression ISO RGD:730923 6480464 Arsenic results in decreased expression of E2F1 mRNA CTD PMID:19945496 arsenic atom multiple interactions ISO RGD:730923 6480464 E2F1 protein affects the reaction [Arsenic results in increased expression of AURKA protein] CTD PMID:23174854 arsenic atom increases expression ISO RGD:730923 6480464 Arsenic results in increased expression of E2F1 protein CTD PMID:23174854 arsenous acid decreases expression ISO RGD:730923 6480464 Arsenic Trioxide results in decreased expression of E2F1 protein CTD PMID:24691991 more ... arsenous acid multiple interactions ISO RGD:730923 6480464 Arsenic Trioxide inhibits the reaction [TP53 protein binds to E2F1 protein] more ... CTD PMID:34042274 arsenous acid affects methylation ISO RGD:730923 6480464 Arsenic Trioxide affects the methylation of E2F1 promoter CTD PMID:26046465 arsenous acid increases expression ISO RGD:730923 6480464 Arsenic Trioxide results in increased expression of E2F1 mRNA CTD PMID:20016248 aspartame multiple interactions EXP 6480464 [Fats more ... CTD PMID:23783067 Aspidin increases expression ISO RGD:730923 6480464 aspidin BB results in increased expression of E2F1 protein CTD PMID:23628508 atrazine decreases expression ISO RGD:730923 6480464 Atrazine results in decreased expression of E2F1 mRNA CTD PMID:22378314 auraptene affects expression ISO RGD:730923 6480464 aurapten affects the expression of E2F1 mRNA CTD PMID:23320178 azoxystrobin decreases expression ISO RGD:730923 6480464 azoxystrobin results in decreased expression of E2F1 mRNA CTD PMID:33512557 benzo[a]pyrene affects activity ISO RGD:730923 6480464 Benzo(a)pyrene affects the activity of E2F1 protein CTD PMID:20624995 benzo[a]pyrene increases methylation ISO RGD:730923 6480464 Benzo(a)pyrene results in increased methylation of E2F1 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:730923 6480464 Benzo(a)pyrene results in decreased expression of E2F1 mRNA, Benzo(a)pyrene results in decreased expression of E2F1 protein CTD PMID:20064835 , PMID:21802500 benzo[a]pyrene increases expression ISO RGD:730923 6480464 Benzo(a)pyrene results in increased expression of E2F1 mRNA, Benzo(a)pyrene results in increased expression of E2F1 protein CTD PMID:16406622 , PMID:32234424 benzo[a]pyrene multiple interactions ISO RGD:730923 6480464 CCND1 protein promotes the reaction [Benzo(a)pyrene results in increased expression of E2F1 protein] more ... CTD PMID:16406622 benzo[a]pyrene diol epoxide I increases expression ISO RGD:730923 6480464 7 more ... CTD PMID:19150397 benzo[d]isothiazol-3-one multiple interactions ISO RGD:730923 6480464 1 more ... CTD PMID:14702633 benzophenanthridine decreases expression ISO RGD:730923 6480464 Benzophenanthridines analog results in decreased expression of E2F1 mRNA CTD PMID:23117580 biotin increases expression EXP 6480464 Biotin results in increased expression of E2F1 mRNA CTD PMID:34699867 bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of E2F1 mRNA CTD PMID:18955075 bisphenol A decreases expression ISO RGD:728892 6480464 bisphenol A results in decreased expression of E2F1 mRNA CTD PMID:25181051 , PMID:34947998 bisphenol A multiple interactions ISO RGD:730923 6480464 [naringenin co-treated with bisphenol A] results in increased expression of E2F1 mRNA, [naringenin metabolite co-treated with bisphenol A] results in increased expression of E2F1 mRNA CTD PMID:36235125 bisphenol A affects expression ISO RGD:730923 6480464 bisphenol A affects the expression of E2F1 mRNA CTD PMID:30903817 bisphenol A increases expression ISO RGD:730923 6480464 bisphenol A results in increased expression of E2F1 mRNA, bisphenol A results in increased expression of E2F1 protein CTD PMID:21277958 more ... bortezomib multiple interactions ISO RGD:730923 6480464 [BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased activity of E2F1 protein CTD PMID:25522274 Butylparaben affects expression ISO RGD:730923 6480464 butylparaben affects the expression of E2F1 mRNA CTD PMID:24481588 cadmium atom decreases expression ISO RGD:730923 6480464 Cadmium results in decreased expression of E2F1 mRNA CTD PMID:20839231 cadmium atom affects methylation ISO RGD:728892 6480464 Cadmium affects the methylation of E2F1 gene CTD PMID:29381301 cadmium dichloride multiple interactions EXP 6480464 Cadmium Chloride inhibits the reaction [SP1 protein binds to SP3 protein binds to KLF4 protein binds to E2F1 protein binds to NECTIN2 promoter] CTD PMID:25046863 cadmium dichloride increases expression ISO RGD:728892 6480464 Cadmium Chloride results in increased expression of E2F1 mRNA CTD PMID:35525383 cadmium dichloride multiple interactions ISO RGD:730923 6480464 MEG3 mRNA inhibits the reaction [Cadmium Chloride results in increased expression of E2F1 protein] CTD PMID:34520792 cadmium dichloride decreases expression ISO RGD:728892 6480464 Cadmium Chloride results in decreased expression of E2F1 mRNA, Cadmium Chloride results in decreased expression of E2F1 protein CTD PMID:33865896 cadmium dichloride increases expression ISO RGD:730923 6480464 Cadmium Chloride results in increased expression of E2F1 mRNA, Cadmium Chloride results in increased expression of E2F1 protein CTD PMID:27510461 more ... caffeine multiple interactions EXP 6480464 Caffeine inhibits the reaction [Camptothecin results in increased expression of E2F1 mRNA] CTD PMID:22403396 calcitriol multiple interactions ISO RGD:730923 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of E2F1 mRNA more ... CTD PMID:21592394 calcitriol decreases expression ISO RGD:730923 6480464 Calcitriol results in decreased expression of E2F1 mRNA CTD PMID:21592394 camptothecin multiple interactions EXP 6480464 7-hydroxystaurosporine inhibits the reaction [Camptothecin results in increased expression of E2F1 mRNA] more ... CTD PMID:22403396 camptothecin increases expression EXP 6480464 Camptothecin results in increased expression of E2F1 mRNA CTD PMID:22403396 cannabidiol decreases expression ISO RGD:730923 6480464 Cannabidiol results in decreased expression of E2F1 mRNA CTD PMID:33244087 cannabidiol increases expression ISO RGD:730923 6480464 Cannabidiol results in increased expression of E2F1 mRNA CTD PMID:27714895 , PMID:27918106 cannabidiol multiple interactions ISO RGD:730923 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of E2F1 mRNA CTD PMID:32992648 capsaicin increases expression ISO RGD:730923 6480464 Capsaicin results in increased expression of E2F1 mRNA CTD PMID:19502594 carbamazepine affects expression ISO RGD:730923 6480464 Carbamazepine affects the expression of E2F1 mRNA CTD PMID:24752500 carbon nanotube affects expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon results in decreased expression of E2F1 mRNA CTD PMID:25620056 Cardanol increases expression ISO RGD:730923 6480464 cardanol results in increased expression of E2F1 mRNA CTD PMID:26694491 carmustine increases expression ISO RGD:730923 6480464 Carmustine results in increased expression of E2F1 protein CTD PMID:18632648 chlorpromazine decreases expression ISO RGD:730923 6480464 Chlorpromazine analog results in decreased expression of E2F1 mRNA CTD PMID:15924885 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of E2F1 mRNA CTD PMID:32715474 choline increases expression EXP 6480464 Choline results in increased expression of E2F1 mRNA CTD PMID:16014740 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of E2F1 gene CTD PMID:20938992 choline increases expression ISO RGD:728892 6480464 Choline results in increased expression of E2F1 mRNA CTD PMID:16014740 chromium(6+) multiple interactions ISO RGD:730923 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of E2F1 mRNA more ... CTD PMID:33677506 cilostazol decreases expression ISO RGD:730923 6480464 cilostazol results in decreased expression of E2F1 protein CTD PMID:15723965 cisplatin increases expression ISO RGD:730923 6480464 Cisplatin results in increased expression of E2F1 mRNA CTD PMID:21603599 cisplatin decreases expression ISO RGD:730923 6480464 Cisplatin results in decreased expression of E2F1 mRNA CTD PMID:24211769 cisplatin increases acetylation ISO RGD:730923 6480464 Cisplatin results in increased acetylation of E2F1 protein CTD PMID:21157427 cobalt atom multiple interactions ISO RGD:728892 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of E2F1 mRNA CTD PMID:22198552 copper atom multiple interactions ISO RGD:730923 6480464 [Chelating Agents binds to Copper] which results in decreased expression of E2F1 mRNA more ... CTD PMID:20971185 more ... copper atom increases expression ISO RGD:728892 6480464 Copper deficiency results in increased expression of E2F1 mRNA CTD PMID:17418555 copper(0) multiple interactions ISO RGD:730923 6480464 [Chelating Agents binds to Copper] which results in decreased expression of E2F1 mRNA more ... CTD PMID:20971185 more ... copper(0) increases expression ISO RGD:728892 6480464 Copper deficiency results in increased expression of E2F1 mRNA CTD PMID:17418555 copper(II) sulfate decreases expression ISO RGD:730923 6480464 Copper Sulfate results in decreased expression of E2F1 mRNA CTD PMID:19549813 coumestrol multiple interactions ISO RGD:730923 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of E2F1 mRNA CTD PMID:19167446 CU-O LINKAGE increases expression ISO RGD:730923 6480464 cupric oxide results in increased expression of E2F1 mRNA CTD PMID:32285662 curcumin decreases expression ISO RGD:728892 6480464 Curcumin results in decreased expression of E2F1 mRNA CTD PMID:18299980 DDT increases expression EXP 6480464 DDT results in increased expression of E2F1 mRNA, DDT results in increased expression of E2F1 protein CTD PMID:23684557 DDT multiple interactions EXP 6480464 fulvestrant inhibits the reaction [DDT results in increased expression of E2F1 mRNA] CTD PMID:23684557 deguelin decreases expression ISO RGD:730923 6480464 deguelin results in decreased expression of E2F1 mRNA CTD PMID:33512557 diarsenic trioxide affects methylation ISO RGD:730923 6480464 Arsenic Trioxide affects the methylation of E2F1 promoter CTD PMID:26046465 diarsenic trioxide multiple interactions ISO RGD:730923 6480464 Arsenic Trioxide inhibits the reaction [TP53 protein binds to E2F1 protein] more ... CTD PMID:34042274 diarsenic trioxide increases expression ISO RGD:730923 6480464 Arsenic Trioxide results in increased expression of E2F1 mRNA CTD PMID:20016248 diarsenic trioxide decreases expression ISO RGD:730923 6480464 Arsenic Trioxide results in decreased expression of E2F1 protein CTD PMID:24691991 more ... dibenzo[a,l]pyrene increases expression ISO RGD:730923 6480464 dibenzo(a, l)pyrene results in increased expression of E2F1 mRNA CTD PMID:16269432 diclofenac affects expression ISO RGD:730923 6480464 Diclofenac affects the expression of E2F1 mRNA CTD PMID:24752500 dieldrin affects expression ISO RGD:728892 6480464 Dieldrin affects the expression of E2F1 mRNA CTD PMID:22546817 dieldrin increases expression ISO RGD:728892 6480464 Dieldrin results in increased expression of E2F1 mRNA CTD PMID:23153324 diethanolamine increases expression EXP 6480464 diethanolamine results in increased expression of E2F1 mRNA CTD PMID:16014740 diethanolamine increases expression ISO RGD:728892 6480464 diethanolamine results in increased expression of E2F1 mRNA CTD PMID:16014740 dihydroxyacetone increases expression ISO RGD:730923 6480464 Dihydroxyacetone results in increased expression of E2F1 mRNA CTD PMID:32506039 dioxygen decreases expression ISO RGD:730923 6480464 Oxygen deficiency results in decreased expression of E2F1 mRNA CTD PMID:26516004 dioxygen multiple interactions ISO RGD:730923 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of E2F1 mRNA, [Oxygen co-treated with Ozone] results in decreased expression of E2F1 mRNA CTD PMID:32992648 doxorubicin affects response to substance ISO RGD:730923 6480464 E2F1 protein affects the susceptibility to Doxorubicin CTD PMID:25124555 doxorubicin increases expression ISO RGD:730923 6480464 Doxorubicin results in increased expression of E2F1 protein CTD PMID:22751436 doxorubicin decreases expression ISO RGD:730923 6480464 Doxorubicin results in decreased expression of E2F1 mRNA, Doxorubicin results in decreased expression of E2F1 protein CTD PMID:24816189 doxorubicin multiple interactions ISO RGD:730923 6480464 Doxorubicin inhibits the reaction [[RBBP8 protein binds to BRCA1 protein binds to E2F1 protein] which results in increased expression of ATM mRNA] more ... CTD PMID:22751436 more ... doxorubicin affects expression ISO RGD:730923 6480464 Doxorubicin affects the expression of E2F1 protein CTD PMID:25124555 elemental selenium increases expression ISO RGD:730923 6480464 Selenium results in increased expression of E2F1 mRNA CTD PMID:19244175 endosulfan decreases expression ISO RGD:730923 6480464 Endosulfan results in decreased expression of E2F1 mRNA CTD PMID:30090376 etoposide multiple interactions ISO RGD:730923 6480464 E2F1 protein affects the reaction [Etoposide results in increased expression of HIC1 mRNA], Etoposide promotes the reaction [E2F1 protein binds to HIC1 promoter] CTD PMID:19491197 eugenol decreases expression ISO RGD:730923 6480464 Eugenol results in decreased expression of E2F1 mRNA, Eugenol results in decreased expression of E2F1 protein CTD PMID:15574415 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of E2F1 gene CTD PMID:20938992 fulvestrant decreases expression ISO RGD:730923 6480464 fulvestrant results in decreased expression of E2F1 mRNA CTD PMID:20215421 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [DDT results in increased expression of E2F1 mRNA] CTD PMID:23684557 furan increases expression ISO RGD:728892 6480464 furan results in increased expression of E2F1 mRNA CTD PMID:20562052 , PMID:22079235 gamma-tocopherol increases expression ISO RGD:730923 6480464 Tocopherols results in increased expression of E2F1 protein CTD PMID:15883045 gefitinib decreases expression ISO RGD:730923 6480464 gefitinib results in decreased expression of E2F1 mRNA, gefitinib results in decreased expression of E2F1 protein CTD PMID:17094457 , PMID:18347146 gentamycin decreases expression ISO RGD:728892 6480464 Gentamicins results in decreased expression of E2F1 mRNA CTD PMID:33387578 geraniol decreases expression ISO RGD:730923 6480464 geraniol results in decreased expression of E2F1 mRNA CTD PMID:27683099 glyphosate decreases expression ISO RGD:730923 6480464 glyphosate results in decreased expression of E2F1 mRNA CTD PMID:31295307 GW 3965 decreases expression ISO RGD:730923 6480464 GW 3965 results in decreased expression of E2F1 mRNA CTD PMID:31437187 harmine increases expression ISO RGD:730923 6480464 Harmine results in increased expression of E2F1 mRNA, Harmine results in increased expression of E2F1 protein CTD PMID:25751815 heparin decreases expression ISO RGD:730923 6480464 Heparin analog results in decreased expression of E2F1 protein CTD PMID:20201787 hydroquinone increases expression ISO RGD:730923 6480464 hydroquinone results in increased expression of E2F1 mRNA, hydroquinone results in increased expression of E2F1 protein CTD PMID:33932074 hydroxyurea decreases expression ISO RGD:730923 6480464 Hydroxyurea results in decreased expression of E2F1 mRNA CTD PMID:24211769 indirubin decreases expression ISO RGD:730923 6480464 indirubin results in decreased expression of E2F1 mRNA CTD PMID:15056799 iron atom multiple interactions ISO RGD:728892 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of E2F1 mRNA CTD PMID:22198552 iron(0) multiple interactions ISO RGD:728892 6480464 [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of E2F1 mRNA CTD PMID:22198552 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of E2F1 gene CTD PMID:20938992 Lasiocarpine multiple interactions ISO RGD:730923 6480464 [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of E2F1 mRNA CTD PMID:33884520 lead nitrate multiple interactions ISO RGD:730923 6480464 E2F1 protein inhibits the reaction [lead nitrate results in decreased expression of DNMT3A mRNA] more ... CTD PMID:24639330 leptomycin B decreases expression ISO RGD:730923 6480464 leptomycin B results in decreased expression of E2F1 mRNA CTD PMID:20803015 lidocaine affects expression EXP 6480464 Lidocaine affects the expression of E2F1 mRNA CTD PMID:18931217 lipopolysaccharide multiple interactions EXP 6480464 E2F1 protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein] more ... CTD PMID:21131441 , PMID:23107598 lipopolysaccharide increases response to substance EXP 6480464 E2F1 protein results in increased susceptibility to Lipopolysaccharides CTD PMID:21131441 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Vanadates results in increased expression of E2F1 protein] CTD PMID:14971663 maneb multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA, Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA] CTD PMID:23963992 melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA] CTD PMID:23963992 menadione affects expression ISO RGD:730923 6480464 Vitamin K 3 affects the expression of E2F1 mRNA CTD PMID:20044591 methotrexate multiple interactions ISO RGD:730923 6480464 Methotrexate inhibits the reaction [RB1 protein binds to E2F1 protein] more ... CTD PMID:22484375 methotrexate multiple interactions EXP 6480464 Methotrexate promotes the reaction [E2F1 protein binds to CHEK1 promoter], Methotrexate promotes the reaction [E2F1 protein binds to DHFR promoter] CTD PMID:22484375 methylseleninic acid decreases expression ISO RGD:730923 6480464 methylselenic acid results in decreased expression of E2F1 mRNA, methylselenic acid results in decreased expression of E2F1 protein CTD PMID:11830524 , PMID:17847021 methylseleninic acid affects expression ISO RGD:730923 6480464 methylselenic acid affects the expression of E2F1 mRNA CTD PMID:14617803 methylseleninic acid multiple interactions ISO RGD:730923 6480464 methylselenic acid promotes the reaction [E2F1 protein binds to RB1 protein] CTD PMID:17847021 mifepristone decreases expression ISO RGD:730923 6480464 Mifepristone results in decreased expression of E2F1 protein CTD PMID:17545545 mitomycin C decreases expression ISO RGD:730923 6480464 Mitomycin results in decreased expression of E2F1 mRNA CTD PMID:24211769 monocrotaline multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA CTD PMID:21224054 monocrotaline multiple interactions ISO RGD:730923 6480464 [CYP3A4 protein results in increased metabolism of Monocrotaline] which results in decreased expression of E2F1 mRNA CTD PMID:33884520 monosodium L-glutamate multiple interactions EXP 6480464 [Fats more ... CTD PMID:23783067 motexafin gadolinium multiple interactions ISO RGD:730923 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F1 mRNA CTD PMID:16357179 motexafin gadolinium increases expression ISO RGD:730923 6480464 motexafin gadolinium results in increased expression of E2F1 mRNA CTD PMID:16357179 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine decreases expression ISO RGD:730923 6480464 N more ... CTD PMID:33645215 N-acetyl-L-cysteine multiple interactions ISO RGD:730923 6480464 Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of E2F1 protein] CTD PMID:16497787 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:730923 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dronabinol results in decreased expression of E2F1 protein] CTD PMID:17934890 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO RGD:730923 6480464 ATR protein promotes the reaction [Methylnitronitrosoguanidine results in increased expression of E2F1 protein] more ... CTD PMID:26921499 N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO RGD:730923 6480464 Methylnitronitrosoguanidine results in increased expression of E2F1 protein CTD PMID:26921499 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of E2F1 mRNA more ... CTD PMID:17854601 more ... N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of E2F1 mRNA, Diethylnitrosamine results in increased expression of E2F1 protein CTD PMID:17854601 , PMID:19887370 nickel atom multiple interactions ISO RGD:728892 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of E2F1 mRNA, [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of E2F1 mRNA CTD PMID:22198552 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of E2F1 mRNA CTD PMID:12729255 nickel dichloride affects expression ISO RGD:728892 6480464 nickel chloride affects the expression of E2F1 mRNA CTD PMID:22546817 nickel dichloride multiple interactions EXP 6480464 HIF1A affects the reaction [nickel chloride results in increased expression of E2F1 mRNA] CTD PMID:12729255 niclosamide decreases expression ISO RGD:730923 6480464 Niclosamide results in decreased expression of E2F1 mRNA CTD PMID:29843133 nicotine increases expression ISO RGD:730923 6480464 Nicotine results in increased expression of E2F1 protein CTD PMID:20061081 nicotine multiple interactions ISO RGD:730923 6480464 MK-886 inhibits the reaction [Nicotine results in increased expression of E2F1 protein] more ... CTD PMID:16601104 more ... Nonylphenol increases expression ISO RGD:730923 6480464 nonylphenol results in increased expression of E2F1 mRNA, nonylphenol results in increased expression of E2F1 protein CTD PMID:33516137 ochratoxin A multiple interactions ISO RGD:730923 6480464 [ochratoxin A results in increased acetylation of E2F1 promoter] which results in increased expression of E2F1 mRNA CTD PMID:29098329 ochratoxin A increases expression ISO RGD:730923 6480464 ochratoxin A results in increased expression of E2F1 mRNA CTD PMID:29098329 ochratoxin A increases acetylation ISO RGD:730923 6480464 ochratoxin A results in increased acetylation of E2F1 promoter CTD PMID:29098329 oleic acid decreases expression ISO RGD:730923 6480464 Oleic Acid results in decreased expression of E2F1 protein CTD PMID:16027227 ozone multiple interactions ISO RGD:730923 6480464 [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of E2F1 mRNA, [Oxygen co-treated with Ozone] results in decreased expression of E2F1 mRNA CTD PMID:32992648 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of E2F1 mRNA, [Air Pollutants results in increased abundance of Ozone] which results in increased expression of E2F1 mRNA CTD PMID:34911549 p-menthan-3-ol increases expression ISO RGD:730923 6480464 Menthol results in increased expression of E2F1 mRNA CTD PMID:26760959 paclitaxel increases response to substance ISO RGD:730923 6480464 E2F1 protein results in increased susceptibility to Paclitaxel CTD PMID:16849574 palbociclib multiple interactions ISO RGD:730923 6480464 palbociclib inhibits the reaction [Doxorubicin results in increased expression of E2F1 protein], RB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased expression of E2F1 protein]] CTD PMID:22751436 paracetamol increases expression ISO RGD:730923 6480464 Acetaminophen results in increased expression of E2F1 mRNA CTD PMID:22230336 , PMID:25704631 paracetamol increases expression ISO RGD:728892 6480464 Acetaminophen results in increased expression of E2F1 mRNA CTD PMID:33387578 paracetamol affects methylation ISO RGD:728892 6480464 Acetaminophen affects the methylation of E2F1 gene CTD PMID:29381301 paraquat multiple interactions EXP 6480464 [Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA, Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA] CTD PMID:23963992 paraquat decreases expression ISO RGD:728892 6480464 Paraquat results in decreased expression of E2F1 mRNA CTD PMID:32680482 parathion decreases expression EXP 6480464 Parathion results in decreased expression of E2F1 mRNA CTD PMID:34813904 pentachlorophenol increases expression ISO RGD:728892 6480464 Pentachlorophenol results in increased expression of E2F1 protein CTD PMID:19442831 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of E2F1 mRNA CTD PMID:23091169 phenytoin multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA CTD PMID:21224054 phosphoramide mustard increases expression ISO RGD:728892 6480464 phosphoramide mustard results in increased expression of E2F1 mRNA CTD PMID:26708502 phthalaldehyde affects expression EXP 6480464 o-Phthalaldehyde affects the expression of E2F1 mRNA CTD PMID:22302311 piperonyl butoxide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of E2F1 mRNA CTD PMID:20101389 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of E2F1 mRNA CTD PMID:23811191 pregnenolone 16alpha-carbonitrile multiple interactions EXP 6480464 [1 more ... CTD PMID:23626729 progesterone decreases expression EXP 6480464 Progesterone results in decreased expression of E2F1 mRNA CTD PMID:16966611 propylparaben increases expression ISO RGD:730923 6480464 propylparaben results in increased expression of E2F1 mRNA CTD PMID:24481588 quercetin increases expression ISO RGD:730923 6480464 Quercetin results in increased expression of E2F1 mRNA CTD PMID:21632981 , PMID:27514524 quinoline affects expression ISO RGD:730923 6480464 quinoline analog affects the expression of E2F1 protein CTD PMID:15450938 resveratrol multiple interactions ISO RGD:730923 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of E2F1 mRNA CTD PMID:19167446 riddelliine multiple interactions ISO RGD:730923 6480464 [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F1 mRNA CTD PMID:33884520 rifampicin multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA CTD PMID:21224054 ritonavir decreases expression ISO RGD:730923 6480464 Ritonavir results in decreased expression of E2F1 mRNA, Ritonavir results in decreased expression of E2F1 protein CTD PMID:19386116 selenium atom increases expression ISO RGD:730923 6480464 Selenium results in increased expression of E2F1 mRNA CTD PMID:19244175 silicon dioxide decreases expression ISO RGD:730923 6480464 Silicon Dioxide analog results in decreased expression of E2F1 mRNA CTD PMID:23806026 silver(1+) nitrate increases expression ISO RGD:730923 6480464 Silver Nitrate analog results in increased expression of E2F1 mRNA CTD PMID:22831968 simvastatin decreases expression ISO RGD:730923 6480464 Simvastatin results in decreased expression of E2F1 mRNA CTD PMID:17428261 sirolimus multiple interactions ISO RGD:730923 6480464 [TGFB1 protein co-treated with Sirolimus] results in decreased expression of E2F1 mRNA, [TGFB1 protein co-treated with Sirolimus] results in decreased expression of E2F1 protein CTD PMID:12417722 sirolimus multiple interactions EXP 6480464 [TGFB1 protein co-treated with Sirolimus] results in decreased expression of E2F1 protein CTD PMID:12417722 sodium arsenite multiple interactions EXP 6480464 sodium arsenite inhibits the reaction [E2F1 protein binds to DLGAP5 promoter] more ... CTD PMID:17998272 , PMID:28003426 sodium arsenite multiple interactions ISO RGD:730923 6480464 sodium arsenite affects the reaction [Estradiol affects the expression of E2F1 protein] more ... CTD PMID:28880708 sodium arsenite increases expression ISO RGD:730923 6480464 sodium arsenite results in increased expression of E2F1 mRNA CTD PMID:28595984 more ... sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of E2F1 protein CTD PMID:10764629 sulforaphane decreases expression ISO RGD:730923 6480464 sulforaphane results in decreased expression of E2F1 mRNA CTD PMID:31838189 sulindac decreases expression ISO RGD:730923 6480464 Sulindac results in decreased expression of E2F1 protein CTD PMID:16488075 tamoxifen multiple interactions ISO RGD:730923 6480464 Tamoxifen promotes the reaction [[[ESR1 protein binds to SP1 protein] which binds to E2F1 promoter] which results in increased expression of E2F1 mRNA], Tamoxifen promotes the reaction [[ESR1 protein binds to SP1 protein] which binds to E2F1 promoter] CTD PMID:20215421 tamoxifen decreases expression ISO RGD:728892 6480464 Tamoxifen results in decreased expression of E2F1 protein CTD PMID:17343880 tamoxifen multiple interactions ISO RGD:728892 6480464 [Tamoxifen results in increased expression of MIR17 mRNA] which results in decreased expression of E2F1 protein, [Tamoxifen results in increased expression of MIR92A1 mRNA] which results in decreased expression of E2F1 protein CTD PMID:17343880 tamoxifen increases expression ISO RGD:730923 6480464 Tamoxifen results in increased expression of E2F1 mRNA, Tamoxifen results in increased expression of E2F1 protein CTD PMID:20215421 tamoxifen decreases expression ISO RGD:730923 6480464 Tamoxifen results in decreased expression of E2F1 mRNA CTD PMID:15590111 tauroursodeoxycholic acid increases expression ISO RGD:728892 6480464 ursodoxicoltaurine results in increased expression of E2F1 mRNA CTD PMID:15255934 tauroursodeoxycholic acid decreases expression ISO RGD:728892 6480464 ursodoxicoltaurine results in decreased expression of E2F1 protein CTD PMID:15255934 tert-butyl hydroperoxide decreases expression ISO RGD:730923 6480464 tert-Butylhydroperoxide results in decreased expression of E2F1 mRNA CTD PMID:12419474 testosterone multiple interactions ISO RGD:730923 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of E2F1 mRNA more ... CTD PMID:21592394 testosterone decreases expression EXP 6480464 Testosterone deficiency results in decreased expression of E2F1 mRNA CTD PMID:33848595 testosterone multiple interactions EXP 6480464 1 more ... CTD PMID:33848595 testosterone decreases expression ISO RGD:730923 6480464 Testosterone results in decreased expression of E2F1 mRNA CTD PMID:21592394 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of E2F1 mRNA, Carbon Tetrachloride results in increased expression of E2F1 protein CTD PMID:17484886 , PMID:19887370 thapsigargin decreases expression ISO RGD:730923 6480464 Thapsigargin results in decreased expression of E2F1 mRNA CTD PMID:22378314 thioacetamide increases expression ISO RGD:728892 6480464 Thioacetamide results in increased expression of E2F1 mRNA CTD PMID:16297948 tocopherol increases expression ISO RGD:730923 6480464 Tocopherols results in increased expression of E2F1 protein CTD PMID:15883045 toluene 2,4-diisocyanate increases expression EXP 6480464 Toluene 2, 4-Diisocyanate results in increased expression of E2F1 mRNA CTD PMID:21404309 trabectedin increases expression EXP 6480464 trabectedin results in increased expression of E2F1 mRNA CTD PMID:15961672 trabectedin increases expression ISO RGD:730923 6480464 trabectedin results in increased expression of E2F1 mRNA CTD PMID:15961672 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of E2F1 mRNA CTD PMID:19042947 trimellitic anhydride affects expression EXP 6480464 trimellitic anhydride affects the expression of E2F1 mRNA CTD PMID:22302311 Triptolide increases expression ISO RGD:728892 6480464 triptolide results in increased expression of E2F1 mRNA CTD PMID:23639586 troglitazone multiple interactions ISO RGD:730923 6480464 [troglitazone co-treated with Aspirin] results in decreased expression of E2F1 protein CTD PMID:19908241 troglitazone decreases expression ISO RGD:730923 6480464 troglitazone results in decreased expression of E2F1 mRNA CTD PMID:19140230 , PMID:19631733 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of E2F1 mRNA CTD PMID:35537566 tungsten multiple interactions ISO RGD:728892 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of E2F1 mRNA, [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of E2F1 mRNA CTD PMID:22198552 tunicamycin decreases expression ISO RGD:730923 6480464 Tunicamycin results in decreased expression of E2F1 mRNA CTD PMID:22378314 urethane increases expression EXP 6480464 Urethane results in increased expression of E2F1 mRNA CTD PMID:12117781 urethane decreases expression ISO RGD:730923 6480464 Urethane results in decreased expression of E2F1 mRNA CTD PMID:28818685 ursodeoxycholic acid multiple interactions ISO RGD:728892 6480464 NR3C1 mutant form inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [TGFB1 protein results in increased expression of E2F1 protein]] more ... CTD PMID:14514686 , PMID:15222754 ursodeoxycholic acid decreases expression ISO RGD:728892 6480464 Ursodeoxycholic Acid results in decreased expression of E2F1 protein CTD PMID:15222754 valproic acid increases expression ISO RGD:730923 6480464 Valproic Acid results in increased expression of E2F1 mRNA CTD PMID:20585447 valproic acid increases methylation ISO RGD:730923 6480464 Valproic Acid results in increased methylation of E2F1 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:730923 6480464 Valproic Acid affects the expression of E2F1 mRNA CTD PMID:25979313 vemurafenib multiple interactions ISO RGD:730923 6480464 [(+)-JQ1 compound co-treated with vemurafenib] results in decreased expression of E2F1 mRNA CTD PMID:27169980 vincaleukoblastine increases response to substance ISO RGD:730923 6480464 E2F1 protein results in increased susceptibility to Vinblastine CTD PMID:16849574 vinyl carbamate decreases expression EXP 6480464 vinyl carbamate results in decreased expression of E2F1 mRNA CTD PMID:17849452 wortmannin multiple interactions EXP 6480464 wortmannin inhibits the reaction [Vanadates results in increased expression of E2F1 protein] CTD PMID:14971663 zinc acetate increases expression ISO RGD:730923 6480464 Zinc Acetate results in increased expression of E2F1 mRNA CTD PMID:16357179 zinc acetate multiple interactions ISO RGD:730923 6480464 [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F1 mRNA CTD PMID:16357179