Cyp11b2<sup>m1</sup> (cytochrome P450, family 11, subfamily b, polypeptide 2; mutation 1) - Rat Genome Database

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Pathways
Gene: Cyp11b2m1 (cytochrome P450, family 11, subfamily b, polypeptide 2; mutation 1) Rattus norvegicus
Analyze
Symbol: Cyp11b2m1
Name: cytochrome P450, family 11, subfamily b, polypeptide 2; mutation 1
RGD ID: 728295
Description: nucleotide 752 (G) in exon 4 of Milan hypertensive (MHS) differs from that of normotensive (MNS) rats (A)
Type: allele  of Cyp11b2  
Previously known as: Cyp11b2m1
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
RGSC_v3.17113,077,595 - 113,084,003 (-)NCBI


References

References - curated
# Reference Title Reference Citation
1. Mutations in aldosterone synthase gene of Milan hypertensive rats: phenotypic consequences. Lloyd-MacGilp SA, etal., Am J Physiol Endocrinol Metab 2002 Mar;282(3):E608-17.

Genomics


Expression


Sequence

Nucleotide Sequences
GenBank Nucleotide X52766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-10-12 Cyp11b2m1        Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function exhibits lower 11- and 18-hydroxylase activities, but higher 18-oxidase activity 727991