Rela (RELA proto-oncogene, NF-kB subunit) - Rat Genome Database

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Gene: Rela (RELA proto-oncogene, NF-kB subunit) Rattus norvegicus
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Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
RGD ID: 727889
Description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of cell differentiation; positive regulation of miRNA transcription; and response to ischemia. Located in cytoplasm and nucleus. Part of chromatin. Is active in synapse. Used to study Parkinsonism; encephalitis; status epilepticus; and steatotic liver disease. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); colitis; end stage renal disease; and liver cirrhosis. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; lung non-small cell carcinoma; lymphoma; and renal cell carcinoma. Orthologous to human RELA (RELA proto-oncogene, NF-kB subunit); PARTICIPATES IN ceramide signaling pathway; interleukin-1 signaling pathway; interleukin-12 signaling pathway; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; (+)-Tetrandrine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: NFkB; nos2; nuclear factor kappa B subunit p65; nuclear factor kappaB subunit p65; transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A (avian)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,354,336 - 212,364,815 (+)NCBIGRCr8
mRatBN7.21202,925,001 - 202,935,484 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1202,924,945 - 202,935,484 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1211,277,590 - 211,288,062 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,370,406 - 218,380,885 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,061,451 - 211,071,930 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,992,770 - 221,003,249 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,992,770 - 221,003,249 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,928,092 - 227,938,571 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,262,669 - 208,273,148 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11208,416,121 - 208,426,601 (+)NCBI
Celera1200,460,753 - 200,471,232 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model