Frmd6 (FERM domain containing 6) - Rat Genome Database

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Gene: Frmd6 (FERM domain containing 6) Rattus norvegicus
Analyze
Symbol: Frmd6
Name: FERM domain containing 6
RGD ID: 727810
Description: Predicted to act upstream of or within apical constriction; protein localization; and regulation of actin filament-based process. Predicted to be located in apical junction complex; cytoplasm; and plasma membrane. Orthologous to human FRMD6 (FERM domain containing 6); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FERM domain-containing protein 163SCII; FERM domain-containing protein 6; FERM-domain-containing protein 163SCII; LOC257646
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8695,081,958 - 95,155,561 (+)NCBIGRCr8
GRCr8 Ensembl695,081,985 - 95,155,560 (+)EnsemblGRCr8 Ensembl
mRatBN7.2689,345,983 - 89,419,579 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl689,346,035 - 89,419,579 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx689,730,030 - 89,803,595 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0690,029,493 - 90,103,062 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,469,004 - 89,542,569 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0693,281,382 - 93,358,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,281,408 - 93,358,840 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06102,731,955 - 102,804,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4692,953,340 - 93,027,451 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera687,828,524 - 87,901,645 (+)NCBICelera
RGSC_v3.1692,994,730 - 93,018,418 (+)NCBI
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
caffeine  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
ethylparaben  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
inulin  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methimazole  (EXP)
methylparaben  (ISO)
Muraglitazar  (EXP)
N-nitrosodiethylamine  (EXP)
Nor-9-carboxy-delta9-THC  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl caffeate  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sulfadimethoxine  (EXP)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
tremolite asbestos  (ISO)
troglitazone  (EXP)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
apical junction complex  (IEA,ISO)
cytoplasm  (IEA,ISO,ISS)
membrane  (IEA)
plasma membrane  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:21685893   PMID:22512338   PMID:32200438  


Genomics

Comparative Map Data
Frmd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8695,081,958 - 95,155,561 (+)NCBIGRCr8
GRCr8 Ensembl695,081,985 - 95,155,560 (+)EnsemblGRCr8 Ensembl
mRatBN7.2689,345,983 - 89,419,579 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl689,346,035 - 89,419,579 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx689,730,030 - 89,803,595 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0690,029,493 - 90,103,062 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,469,004 - 89,542,569 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0693,281,382 - 93,358,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl693,281,408 - 93,358,840 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06102,731,955 - 102,804,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4692,953,340 - 93,027,451 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera687,828,524 - 87,901,645 (+)NCBICelera
RGSC_v3.1692,994,730 - 93,018,418 (+)NCBI
Cytogenetic Map6q24NCBI
FRMD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381451,396,431 - 51,730,727 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1451,489,100 - 51,730,727 (+)EnsemblGRCh38hg38GRCh38
GRCh371451,955,846 - 52,197,445 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361451,025,605 - 51,267,195 (+)NCBINCBI36Build 36hg18NCBI36
Build 341451,188,377 - 51,266,922NCBI
Celera1431,822,811 - 32,064,436 (+)NCBICelera
Cytogenetic Map14q22.1NCBI
HuRef1432,116,250 - 32,357,991 (+)NCBIHuRef
CHM1_11451,894,360 - 52,135,960 (+)NCBICHM1_1
T2T-CHM13v2.01445,603,294 - 45,937,636 (+)NCBIT2T-CHM13v2.0
Frmd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391270,872,235 - 70,949,009 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1270,872,288 - 70,949,008 (+)EnsemblGRCm39 Ensembl
GRCm381270,825,456 - 70,902,234 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1270,825,514 - 70,902,234 (+)EnsemblGRCm38mm10GRCm38
MGSCv371271,926,501 - 72,003,221 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361271,744,119 - 71,820,839 (+)NCBIMGSCv36mm8
Celera1271,929,406 - 72,006,218 (+)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1229.37NCBI
Frmd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540911,262,204 - 11,302,146 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540911,262,456 - 11,420,892 (-)NCBIChiLan1.0ChiLan1.0
FRMD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21552,502,344 - 52,868,917 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11451,806,969 - 52,085,426 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01432,093,017 - 32,334,665 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11450,540,191 - 50,620,955 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1450,540,193 - 50,620,955 (+)Ensemblpanpan1.1panPan2
FRMD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1827,757,320 - 27,989,319 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl827,952,398 - 27,987,024 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha827,509,615 - 27,742,043 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0827,934,649 - 28,166,956 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl828,092,880 - 28,166,956 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1827,604,816 - 27,836,513 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0827,664,576 - 27,897,009 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0828,012,258 - 28,244,423 (+)NCBIUU_Cfam_GSD_1.0
Frmd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864060,130,802 - 60,221,267 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649513,970,408 - 14,061,010 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649513,969,753 - 14,060,946 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1181,338,525 - 181,416,840 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11181,338,404 - 181,416,813 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21201,656,066 - 201,698,230 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FRMD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12428,768,362 - 28,849,556 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2428,808,551 - 28,849,600 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605316,905,156 - 17,153,697 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frmd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473117,282,088 - 17,359,754 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473117,284,024 - 17,380,406 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Frmd6
273 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:118
Count of miRNA genes:53
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000009610, ENSRNOT00000068757
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat

Markers in Region
RH133851  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,419,220 - 89,419,405 (+)MAPPERmRatBN7.2
Rnor_6.0693,358,482 - 93,358,666NCBIRnor6.0
Rnor_5.06102,804,621 - 102,804,805UniSTSRnor5.0
RGSC_v3.4693,027,093 - 93,027,277UniSTSRGSC3.4
Celera687,901,287 - 87,901,471UniSTS
RH 3.4 Map6640.4UniSTS
Cytogenetic Map6q24UniSTS
RH143745  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2689,418,622 - 89,418,842 (+)MAPPERmRatBN7.2
Rnor_6.0693,357,884 - 93,358,103NCBIRnor6.0
Rnor_5.06102,804,023 - 102,804,242UniSTSRnor5.0
RGSC_v3.4693,026,495 - 93,026,714UniSTSRGSC3.4
Celera687,900,689 - 87,900,908UniSTS
RH 3.4 Map6637.0UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 49 113 91 90 59 25 59 6 218 97 11 93 45 60 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000009610   ⟹   ENSRNOP00000009610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl689,346,035 - 89,419,579 (+)Ensembl
Rnor_6.0 Ensembl693,281,408 - 93,358,840 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100346   ⟹   ENSRNOP00000079134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl695,081,985 - 95,155,560 (+)Ensembl
mRatBN7.2 Ensembl689,346,040 - 89,419,556 (+)Ensembl
RefSeq Acc Id: NM_001271054   ⟹   NP_001257983
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,081,986 - 95,155,561 (+)NCBI
mRatBN7.2689,346,003 - 89,419,579 (+)NCBI
Rnor_6.0693,281,408 - 93,358,840 (+)NCBI
Rnor_5.06102,731,955 - 102,804,979 (+)NCBI
Celera687,828,524 - 87,901,645 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001399291   ⟹   NP_001386220
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,081,986 - 95,155,561 (+)NCBI
mRatBN7.2689,346,003 - 89,419,579 (+)NCBI
RefSeq Acc Id: NM_001399292   ⟹   NP_001386221
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,081,986 - 95,155,561 (+)NCBI
mRatBN7.2689,346,003 - 89,419,579 (+)NCBI
RefSeq Acc Id: XM_063261564   ⟹   XP_063117634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,081,958 - 95,155,561 (+)NCBI
RefSeq Acc Id: XM_063261565   ⟹   XP_063117635
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,081,975 - 95,155,561 (+)NCBI
RefSeq Acc Id: XM_063261566   ⟹   XP_063117636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,082,202 - 95,155,561 (+)NCBI
RefSeq Acc Id: XM_063261567   ⟹   XP_063117637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,081,958 - 95,155,561 (+)NCBI
RefSeq Acc Id: XM_063261568   ⟹   XP_063117638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8695,081,975 - 95,155,561 (+)NCBI
RefSeq Acc Id: NP_001257983   ⟸   NM_001271054
- Peptide Label: isoform 2
- UniProtKB: A0A8I5ZM66 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009610   ⟸   ENSRNOT00000009610
Ensembl Acc Id: ENSRNOP00000079134   ⟸   ENSRNOT00000100346
RefSeq Acc Id: NP_001386221   ⟸   NM_001399292
- Peptide Label: isoform 2
- UniProtKB: A0A8I5ZM66 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386220   ⟸   NM_001399291
- Peptide Label: isoform 1
- UniProtKB: F1LR29 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117634   ⟸   XM_063261564
- Peptide Label: isoform X1
- UniProtKB: F1LR29 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117637   ⟸   XM_063261567
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZM66 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117635   ⟸   XM_063261565
- Peptide Label: isoform X1
- UniProtKB: F1LR29 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117638   ⟸   XM_063261568
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZM66 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117636   ⟸   XM_063261566
- Peptide Label: isoform X1
- UniProtKB: F1LR29 (UniProtKB/TrEMBL)
Protein Domains
FERM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VII0-F1-model_v2 AlphaFold Q8VII0 1-327 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694645
Promoter ID:EPDNEW_R5168
Type:initiation region
Name:Frmd6_1
Description:FERM domain containing 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0693,281,432 - 93,281,492EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727810 AgrOrtholog
BioCyc Gene G2FUF-37199 BioCyc
Ensembl Genes ENSRNOG00000007329 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000100346 ENTREZGENE
Gene3D-CATH 1.20.80.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/Swiss-Prot
InterPro Band_41_domain UniProtKB/Swiss-Prot
  FERM/acyl-CoA-bd_prot_sf UniProtKB/Swiss-Prot
  FERM_2 UniProtKB/Swiss-Prot
  FERM_central UniProtKB/Swiss-Prot
  FERM_domain UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
  FERM_PH-like_C UniProtKB/Swiss-Prot
  FRMD6-FERM_C UniProtKB/Swiss-Prot
  FRMD6-like UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  Ubiquitin-like_domsf UniProtKB/Swiss-Prot
NCBI Gene 257646 ENTREZGENE
PANTHER FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY UniProtKB/Swiss-Prot
  FERM DOMAIN-CONTAINING PROTEIN 6 UniProtKB/Swiss-Prot
Pfam FERM_C UniProtKB/Swiss-Prot
  FERM_M UniProtKB/Swiss-Prot
  FERM_N UniProtKB/Swiss-Prot
PhenoGen Frmd6 PhenoGen
PROSITE FERM_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007329 RatGTEx
SMART B41 UniProtKB/Swiss-Prot
  FERM_C UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF47031 UniProtKB/Swiss-Prot
  SSF54236 UniProtKB/Swiss-Prot
UniProt A0A8I5ZM66 ENTREZGENE, UniProtKB/TrEMBL
  F1LR29 ENTREZGENE, UniProtKB/TrEMBL
  FRMD6_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Frmd6  FERM domain containing 6  LOC257646  FERM-domain-containing protein 163SCII  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-09-30 LOC257646        Symbol and Name status set to provisional 70820 PROVISIONAL