FAM95C (family with sequence similarity 95 member C) - Rat Genome Database

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Gene: FAM95C (family with sequence similarity 95 member C) Homo sapiens
Analyze
Symbol: FAM95C (Ensembl: ANKRD18A)
Name: family with sequence similarity 95 member C (Ensembl:ankyrin repeat domain 18A)
RGD ID: 7242150
HGNC Page HGNC:45272
Description: INTERACTS WITH aristolochic acid A; lipopolysaccharide; propofol
Type: ncrna (Ensembl: protein-coding)
RefSeq Status: VALIDATED
RGD Orthologs
Mouse
Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38938,540,567 - 38,545,372 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl938,540,567 - 38,620,596 (-)EnsemblGRCh38hg38GRCh38
GRCh37938,540,564 - 38,545,369 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map9p13.1NCBI
HuRef938,492,875 - 38,497,680 (-)NCBIHuRef
CHM1_1938,542,343 - 38,547,148 (-)NCBICHM1_1
T2T-CHM13v2.0938,564,763 - 38,569,568 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14702039  


Genomics

Comparative Map Data
FAM95C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38938,540,567 - 38,545,372 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl938,540,567 - 38,620,596 (-)EnsemblGRCh38hg38GRCh38
GRCh37938,540,564 - 38,545,369 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map9p13.1NCBI
HuRef938,492,875 - 38,497,680 (-)NCBIHuRef
CHM1_1938,542,343 - 38,547,148 (-)NCBICHM1_1
T2T-CHM13v2.0938,564,763 - 38,569,568 (-)NCBIT2T-CHM13v2.0
Gm57858
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39336,061,396 - 36,107,676 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl336,061,393 - 36,107,696 (-)EnsemblGRCm39 Ensembl
GRCm38336,007,247 - 36,053,547 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl336,007,244 - 36,053,547 (-)EnsemblGRCm38mm10GRCm38
MGSCv37335,906,169 - 35,952,469 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36336,198,796 - 36,245,096 (-)NCBIMGSCv36mm8
Celera335,889,674 - 35,936,124 (-)NCBICelera
Cytogenetic Map3BNCBI
cM Map317.41NCBI
4921524L21Rikl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81759,376,110 - 59,416,150 (-)NCBIGRCr8
mRatBN7.21754,681,040 - 54,721,106 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1754,681,044 - 54,720,740 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01757,507,650 - 57,526,428 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1757,507,659 - 57,526,461 (-)EnsemblRnor6.0rn6Rnor6.0
Cytogenetic Map17q12.1NCBI


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 9p24.3-q34.3(chr9:204193-138179445) copy number gain See cases [RCV000133791] Chr9:204193..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p13.3-13.1(chr9:35623500-38815474)x3 copy number gain See cases [RCV000134038] Chr9:35623500..38815474 [GRCh38]
Chr9:35623497..38815471 [GRCh37]
Chr9:35613497..38805471 [NCBI36]
Chr9:9p13.3-13.1
pathogenic
GRCh38/hg38 9p24.3-q21.11(chr9:13997-68401065)x3 copy number gain See cases [RCV000135344] Chr9:13997..68401065 [GRCh38]
Chr9:13997..71015981 [GRCh37]
Chr9:3997..70205801 [NCBI36]
Chr9:9p24.3-q21.11
pathogenic
GRCh38/hg38 9p24.3-q21.12(chr9:193412-70630731)x3 copy number gain See cases [RCV000136152] Chr9:193412..70630731 [GRCh38]
Chr9:220253..73245647 [GRCh37]
Chr9:210253..72435467 [NCBI36]
Chr9:9p24.3-q21.12
pathogenic
GRCh38/hg38 9p24.3-q21.13(chr9:193412-74615913)x3 copy number gain See cases [RCV000135954] Chr9:193412..74615913 [GRCh38]
Chr9:204193..77230829 [GRCh37]
Chr9:194193..76420649 [NCBI36]
Chr9:9p24.3-q21.13
pathogenic
GRCh38/hg38 9p24.3-q21.11(chr9:204104-66233120)x4 copy number gain See cases [RCV000137888] Chr9:204104..66233120 [GRCh38]
Chr9:204104..47212321 [GRCh37]
Chr9:194104..47002141 [NCBI36]
Chr9:9p24.3-q21.11
pathogenic|conflicting data from submitters
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124524)x3 copy number gain See cases [RCV000138783] Chr9:193412..138124524 [GRCh38]
Chr9:204090..141018976 [GRCh37]
Chr9:194090..140138797 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q21.11(chr9:204104-67549861)x3 copy number gain See cases [RCV000139208] Chr9:204104..67549861 [GRCh38]
Chr9:204104..66516698 [GRCh37]
Chr9:194104..66256518 [NCBI36]
Chr9:9p24.3-q21.11
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138159073)x3 copy number gain See cases [RCV000138962] Chr9:193412..138159073 [GRCh38]
Chr9:204104..141053525 [GRCh37]
Chr9:194104..140173346 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic|conflicting data from submitters
GRCh38/hg38 9p24.3-13.1(chr9:204104-38768294)x3 copy number gain See cases [RCV000139126] Chr9:204104..38768294 [GRCh38]
Chr9:204104..38768291 [GRCh37]
Chr9:194104..38758291 [NCBI36]
Chr9:9p24.3-13.1
pathogenic
GRCh38/hg38 9p22.2-q21.11(chr9:18344605-68257015) copy number gain See cases [RCV000140448] Chr9:18344605..68257015 [GRCh38]
Chr9:18344603..68995221 [GRCh37]
Chr9:18334603..68285041 [NCBI36]
Chr9:9p22.2-q21.11
pathogenic
GRCh38/hg38 9p24.3-q22.1(chr9:203861-88130444)x4 copy number gain See cases [RCV000141904] Chr9:203861..88130444 [GRCh38]
Chr9:203861..90745359 [GRCh37]
Chr9:193861..89935179 [NCBI36]
Chr9:9p24.3-q22.1
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:203861-138125937)x3 copy number gain See cases [RCV000141876] Chr9:203861..138125937 [GRCh38]
Chr9:203861..141020389 [GRCh37]
Chr9:193861..140140210 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p21.1-q21.11(chr9:31426827-68257015)x3 copy number gain See cases [RCV000141663] Chr9:31426827..68257015 [GRCh38]
Chr9:31426825..68330127 [GRCh37]
Chr9:31416825..67819947 [NCBI36]
Chr9:9p21.1-q21.11
pathogenic
GRCh38/hg38 9p21.1-13.1(chr9:28975663-38787483)x3 copy number gain See cases [RCV000142317] Chr9:28975663..38787483 [GRCh38]
Chr9:28975661..38787480 [GRCh37]
Chr9:28965661..38777480 [NCBI36]
Chr9:9p21.1-13.1
likely pathogenic
GRCh38/hg38 9p24.3-q21.31(chr9:193412-79877816)x3 copy number gain See cases [RCV000143012] Chr9:193412..79877816 [GRCh38]
Chr9:204104..82492731 [GRCh37]
Chr9:194104..81682551 [NCBI36]
Chr9:9p24.3-q21.31
pathogenic
GRCh38/hg38 9p13.1(chr9:38381815-38787483)x4 copy number gain See cases [RCV000143412] Chr9:38381815..38787483 [GRCh38]
Chr9:38381812..38787480 [GRCh37]
Chr9:38371812..38777480 [NCBI36]
Chr9:9p13.1
uncertain significance
GRCh38/hg38 9p24.3-q34.3(chr9:203862-138125937)x3 copy number gain See cases [RCV000143476] Chr9:203862..138125937 [GRCh38]
Chr9:203862..141020389 [GRCh37]
Chr9:193862..140140210 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-13.1(chr9:204193-38815478)x3 copy number gain See cases [RCV000148159] Chr9:204193..38815478 [GRCh38]
Chr9:204193..38815475 [GRCh37]
Chr9:194193..38805475 [NCBI36]
Chr9:9p24.3-13.1
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain See cases [RCV000148113] Chr9:193412..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-13.1(chr9:204193-38815478)x3 copy number gain See cases [RCV000050357] Chr9:204193..38815478 [GRCh38]
Chr9:204193..38815475 [GRCh37]
Chr9:194193..38805475 [NCBI36]
Chr9:9p24.3-13.1
pathogenic|conflicting interpretations of pathogenicity|conflicting data from submitters
GRCh38/hg38 9p11.2-q34.3(chr9:193412-138159073)x3 copy number gain See cases [RCV000139207] Chr9:193412..138159073 [GRCh38]
Chr9:68420641..141053525 [GRCh37]
Chr9:67910461..140173346 [NCBI36]
Chr9:9p11.2-q34.3
pathogenic
GRCh38/hg38 9p24.3-13.1(chr9:204193-38741440)x3 copy number gain See cases [RCV000051106] Chr9:204193..38741440 [GRCh38]
Chr9:204193..38741437 [GRCh37]
Chr9:194193..38731437 [NCBI36]
Chr9:9p24.3-13.1
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124532)x3 copy number gain See cases [RCV000053745] Chr9:193412..138124532 [GRCh38]
Chr9:204193..141018984 [GRCh37]
Chr9:194193..140138805 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-13.1(chr9:220253-38815419)x3 copy number gain See cases [RCV000053747] Chr9:220253..38815419 [GRCh38]
Chr9:220253..38815416 [GRCh37]
Chr9:210253..38805416 [NCBI36]
Chr9:9p24.3-13.1
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|See cases [RCV000053748] Chr9:193412..138179445 [GRCh38]
Chr9:266045..141073897 [GRCh37]
Chr9:256045..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138114463)x3 copy number gain See cases [RCV000053746] Chr9:193412..138114463 [GRCh38]
Chr9:214367..141008915 [GRCh37]
Chr9:204367..140128736 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-13.1(chr9:203993-38815619)x3 copy number gain See cases [RCV000053703] Chr9:203993..38815619 [GRCh38]
Chr9:203993..38815616 [GRCh37]
Chr9:193993..38805616 [NCBI36]
Chr9:9p24.3-13.1
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain See cases [RCV000050348] Chr9:193412..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
Markers in Region
RH12064  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37938,540,653 - 38,540,811UniSTSGRCh37
Build 36938,530,653 - 38,530,811RGDNCBI36
Celera938,473,595 - 38,473,753RGD
Cytogenetic Map9p13.1UniSTS
HuRef938,492,964 - 38,493,122UniSTS
GeneMap99-GB4 RH Map9148.92UniSTS
NCBI RH Map9549.6UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
1 18 31 15 18 15 214 15 264 232 31 16 30 3

Sequence


Ensembl Acc Id: ENST00000625242
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl938,540,569 - 38,545,372 (-)Ensembl
Ensembl Acc Id: ENST00000636756
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl938,543,253 - 38,577,156 (-)Ensembl
Ensembl Acc Id: ENST00000637288   ⟹   ENSP00000489798
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl938,540,683 - 38,577,203 (-)Ensembl
Ensembl Acc Id: ENST00000637322   ⟹   ENSP00000489764
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl938,540,569 - 38,571,152 (-)Ensembl
Ensembl Acc Id: ENST00000637556   ⟹   ENSP00000490788
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl938,540,569 - 38,577,207 (-)Ensembl
RefSeq Acc Id: NR_047651
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38938,540,567 - 38,545,372 (-)NCBI
GRCh37938,540,564 - 38,545,369 (-)NCBI
HuRef938,492,875 - 38,497,680 (-)NCBI
CHM1_1938,542,343 - 38,547,148 (-)NCBI
T2T-CHM13v2.0938,564,763 - 38,569,568 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:45272 AgrOrtholog
COSMIC FAM95C COSMIC
Ensembl Genes ENSG00000180071 Ensembl, ENTREZGENE
  ENSG00000283486 Ensembl
Ensembl Transcript ENST00000625242 ENTREZGENE
GTEx ENSG00000180071 GTEx
  ENSG00000283486 GTEx
HGNC ID HGNC:45272 ENTREZGENE
Human Proteome Map FAM95C Human Proteome Map
NCBI Gene FAM95C ENTREZGENE
RNAcentral URS000075ABDD RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 FAM95C  family with sequence similarity 95 member C    family with sequence similarity 95, member C  Symbol and/or name change 5135510 APPROVED