Slc27a2 (solute carrier family 27 member 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Slc27a2 (solute carrier family 27 member 2) Rattus norvegicus
Analyze
Symbol: Slc27a2
Name: solute carrier family 27 member 2
RGD ID: 71103
Description: Enables long-chain fatty acid-CoA ligase activity and very long-chain fatty acid-CoA ligase activity. Involved in long-chain fatty acid metabolic process. Located in endoplasmic reticulum and peroxisomal membrane. Orthologous to human SLC27A2 (solute carrier family 27 member 2); PARTICIPATES IN phytanic acid degradation pathway; Refsum disease pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: arachidonate--CoA ligase; FATP-2; fatty acid transport protein 2; fatty-acid-coenzyme A ligase, very long-chain 1; long-chain fatty acid transport protein 2; long-chain-fatty-acid--CoA ligase; MGC93337; phytanate--CoA ligase; solute carrier family 27 (fatty acid transporter) member 2; solute carrier family 27 (fatty acid transporter), member 2; solute carrier family 27 (fatty acid transporter), member 32; THCA-CoA ligase; very long-chain acyl-CoA synthetase; very long-chain-fatty-acid-CoA ligase; VLACS; VLCS
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83134,258,101 - 134,295,581 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3134,258,101 - 134,295,581 (+)EnsemblGRCr8
mRatBN7.23113,804,728 - 113,842,208 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3113,804,728 - 113,842,208 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3117,687,726 - 117,725,657 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03126,283,254 - 126,321,189 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03123,943,634 - 123,981,567 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,014,620 - 119,052,531 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,014,620 - 119,052,531 (+)Ensemblrn6Rnor6.0
Rnor_5.03125,542,772 - 125,580,197 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43114,072,570 - 114,114,269 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3112,647,886 - 112,684,776 (+)NCBICelera
RGSC_v3.13113,978,142 - 114,019,842 (+)NCBI
Cytogenetic Map3q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
adefovir pivoxil  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
amphotericin B  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
benzylpenicillin  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (EXP)
bezafibrate  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chlorothalonil  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
D-glucose  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dipentyl phthalate  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
erythromycin A  (ISO)
ethanol  (EXP,ISO)
farnesol  (ISO)
fenofibrate  (EXP,ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
fructose  (ISO)
fumonisin B1  (ISO)
furan  (EXP)
gemfibrozil  (EXP)
genistein  (ISO)
glucose  (ISO)
GW 4064  (ISO)
GW 7647  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
indometacin  (EXP)
isotretinoin  (ISO)
L-ethionine  (EXP)
lead diacetate  (ISO)
lead(0)  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (EXP)
nicotinic acid  (ISO)
nitrofen  (EXP)
Nutlin-3  (ISO)
okadaic acid  (ISO)
olanzapine  (ISO)
oleic acid  (ISO)
omeprazole  (EXP)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pravastatin  (EXP,ISO)
procymidone  (ISO)
progesterone  (ISO)
propamocarb  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (EXP)
tert-butyl ethyl ether  (EXP)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zidovudine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
endoplasmic reticulum  (IDA,IEA,ISO)
endoplasmic reticulum lumen  (IEA,ISO,ISS)
endoplasmic reticulum membrane  (IBA,IEA,ISO)
membrane  (IEA)
peroxisomal membrane  (IBA,IDA,IEA,ISO,ISS)
peroxisome  (IDA,IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
4. Cellular cholesterol stimulates acute uptake of palmitate by redistribution of fatty acid translocase in type II pneumocytes. Kolleck I, etal., Biochemistry 2002 May 21;41(20):6369-75.
5. Molecular organization of peroxisomal enzymes: protein-protein interactions in the membrane and in the matrix. Makkar RS, etal., Arch Biochem Biophys. 2006 Jul 15;451(2):128-40. Epub 2006 May 24.
6. Gene Data Set MGD Curation, June 12, 2002
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway. Ohkuni A, etal., Biochem Biophys Res Commun. 2013 Dec 13;442(3-4):195-201. doi: 10.1016/j.bbrc.2013.11.036. Epub 2013 Nov 19.
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Intraperoxisomal localization of very-long-chain fatty acyl-CoA synthetase: implication in X-adrenoleukodystrophy. Smith BT, etal., Exp Cell Res. 2000 Feb 1;254(2):309-20.
16. Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism. Steinberg SJ, etal., Biochem Biophys Res Commun. 1999 Apr 13;257(2):615-21.
17. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
18. Molecular cloning of cDNA encoding rat very long-chain acyl-CoA synthetase. Uchiyama A, etal., J Biol Chem 1996 Nov 29;271(48):30360-5.
Additional References at PubMed
PMID:9271215   PMID:9671728   PMID:10749848   PMID:11980911   PMID:12048192   PMID:12719378   PMID:14651853   PMID:15699031   PMID:19056867   PMID:20142826   PMID:20178365   PMID:20530735  
PMID:21768100   PMID:22022213   PMID:23376485   PMID:28993506  


Genomics

Comparative Map Data
Slc27a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83134,258,101 - 134,295,581 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3134,258,101 - 134,295,581 (+)EnsemblGRCr8
mRatBN7.23113,804,728 - 113,842,208 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3113,804,728 - 113,842,208 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3117,687,726 - 117,725,657 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03126,283,254 - 126,321,189 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03123,943,634 - 123,981,567 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,014,620 - 119,052,531 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,014,620 - 119,052,531 (+)Ensemblrn6Rnor6.0
Rnor_5.03125,542,772 - 125,580,197 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43114,072,570 - 114,114,269 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3112,647,886 - 112,684,776 (+)NCBICelera
RGSC_v3.13113,978,142 - 114,019,842 (+)NCBI
Cytogenetic Map3q36NCBI
SLC27A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381550,182,196 - 50,236,385 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1550,182,196 - 50,236,385 (+)Ensemblhg38GRCh38
GRCh371550,474,393 - 50,528,582 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361548,261,714 - 48,315,862 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341548,261,713 - 48,315,862NCBI
Celera1527,367,005 - 27,421,191 (+)NCBICelera
Cytogenetic Map15q21.2NCBI
HuRef1527,305,393 - 27,359,548 (+)NCBIHuRef
CHM1_11550,592,321 - 50,646,529 (+)NCBICHM1_1
T2T-CHM13v2.01547,990,417 - 48,044,633 (+)NCBIT2T-CHM13v2.0
Slc27a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392126,394,944 - 126,430,163 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2126,394,327 - 126,430,163 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382126,553,024 - 126,588,243 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2126,552,407 - 126,588,243 (+)Ensemblmm10GRCm38
MGSCv372126,378,760 - 126,413,979 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362126,244,596 - 126,279,377 (+)NCBIMGSCv36mm8
Celera2127,790,803 - 127,826,187 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map261.76NCBI
Slc27a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554094,077,149 - 4,112,828 (-)Ensembl
ChiLan1.0NW_0049554094,077,685 - 4,112,828 (-)NCBIChiLan1.0ChiLan1.0
SLC27A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21639,422,327 - 39,474,538 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11543,606,084 - 43,658,662 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01529,130,262 - 29,182,752 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11547,452,227 - 47,505,066 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1547,452,227 - 47,505,066 (+)EnsemblpanPan2panpan1.1
SLC27A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13016,155,932 - 16,196,919 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3016,156,063 - 16,196,829 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3016,082,144 - 16,122,978 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03016,299,840 - 16,340,742 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3016,299,931 - 16,340,726 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13016,222,402 - 16,263,283 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03016,339,970 - 16,380,747 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03016,446,344 - 16,487,168 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc27a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864094,411,670 - 94,450,694 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647112,259,734 - 12,298,760 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647112,259,779 - 12,298,760 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC27A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1121,526,295 - 121,579,120 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11121,530,449 - 121,578,994 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21135,172,705 - 135,221,753 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC27A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12633,080,844 - 33,134,467 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2633,083,317 - 33,134,433 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666048108,014,439 - 108,068,707 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc27a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247319,862,731 - 9,896,661 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247319,862,948 - 9,896,064 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc27a2
141 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:340
Count of miRNA genes:125
Interacting mature miRNAs:137
Transcripts:ENSRNOT00000013605, ENSRNOT00000067700
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)396509147141509147Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
1582216Bw65Body weight QTL 656.3body mass (VT:0001259)body weight (CMO:0000012)3122654702136118980Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1582219Bw63Body weight QTL 633.80.001body mass (VT:0001259)body weight (CMO:0000012)3116582412136118980Rat
1582221Kidm30Kidney mass QTL 303.50.0008kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)385062224136118980Rat
1582210Bw71Body weight QTL 713.30.0012body mass (VT:0001259)body weight (CMO:0000012)385062224136118980Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)381425008141509147Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)393829559138829559Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
2302273Gluco35Glucose level QTL 355.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3101255536134750886Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)396509147141509147Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)390755164141509147Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)3125814931139636791Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
D3Got230  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23113,804,232 - 113,804,401 (+)MAPPERmRatBN7.2
Rnor_6.03119,014,125 - 119,014,293NCBIRnor6.0
Rnor_5.03125,542,277 - 125,542,445UniSTSRnor5.0
RGSC_v3.43114,072,075 - 114,072,243UniSTSRGSC3.4
Celera3112,647,391 - 112,647,559UniSTS
Cytogenetic Map3q36UniSTS
RH128972  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23113,841,956 - 113,842,152 (+)MAPPERmRatBN7.2
Rnor_6.03119,052,280 - 119,052,475NCBIRnor6.0
Rnor_5.03125,579,946 - 125,580,141UniSTSRnor5.0
RGSC_v3.43114,114,018 - 114,114,213UniSTSRGSC3.4
Celera3112,684,525 - 112,684,720UniSTS
RH 3.4 Map3988.0UniSTS
Cytogenetic Map3q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 10 46 149 91 90 59 86 59 6 325 163 11 121 81 89 31 11 11

Sequence


Ensembl Acc Id: ENSRNOT00000013605   ⟹   ENSRNOP00000013607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3119,015,412 - 119,052,222 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000067700   ⟹   ENSRNOP00000059771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3134,258,101 - 134,295,581 (+)Ensembl
mRatBN7.2 Ensembl3113,804,728 - 113,842,208 (+)Ensembl
Rnor_6.0 Ensembl3119,014,620 - 119,052,531 (+)Ensembl
RefSeq Acc Id: NM_031736   ⟹   NP_113924
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83134,258,101 - 134,295,581 (+)NCBI
mRatBN7.23113,804,728 - 113,842,208 (+)NCBI
Rnor_6.03119,014,620 - 119,052,531 (+)NCBI
Rnor_5.03125,542,772 - 125,580,197 (+)NCBI
RGSC_v3.43114,072,570 - 114,114,269 (+)RGD
Celera3112,647,886 - 112,684,776 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_113924 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81766 (Get FASTA)   NCBI Sequence Viewer  
  BAA12722 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000059771
GenBank Protein P97524 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113924   ⟸   NM_031736
- UniProtKB: P97524 (UniProtKB/Swiss-Prot),   D3ZSL9 (UniProtKB/TrEMBL),   Q66HN6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000059771   ⟸   ENSRNOT00000067700
Ensembl Acc Id: ENSRNOP00000013607   ⟸   ENSRNOT00000013605
Protein Domains
AMP-binding enzyme C-terminal   AMP-dependent synthetase/ligase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97524-F1-model_v2 AlphaFold P97524 1-620 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692388
Promoter ID:EPDNEW_R2913
Type:initiation region
Name:Slc27a2_1
Description:solute carrier family 27 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03119,015,273 - 119,015,333EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71103 AgrOrtholog
BioCyc Gene G2FUF-48024 BioCyc
BioCyc Pathway PWY-5143 [long-chain fatty acid activation] BioCyc
  PWY-5972 [stearate biosynthesis I (animals)] BioCyc
  PWY-6000 [gamma-linolenate biosynthesis II (animals)] BioCyc
  PWY-6061 [bile acid biosynthesis, neutral pathway] BioCyc
  PWY3DJ-11470 [sphingosine and sphingosine-1-phosphate metabolism] BioCyc
BioCyc Pathway Image PWY-5143 BioCyc
  PWY-5972 BioCyc
  PWY-6000 BioCyc
  PWY-6061 BioCyc
  PWY3DJ-11470 BioCyc
Ensembl Genes ENSRNOG00000010128 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000067700 ENTREZGENE
Gene3D-CATH 3.30.300.30 UniProtKB/Swiss-Prot
  3.40.50.12780 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7106977 IMAGE-MGC_LOAD
InterPro AMP-bd_C UniProtKB/Swiss-Prot
  AMP-bd_C_sf UniProtKB/Swiss-Prot
  AMP-binding_CS UniProtKB/Swiss-Prot
  AMP-dep_Synth/Lig UniProtKB/Swiss-Prot
  AMP-dep_Synthh-like_sf UniProtKB/Swiss-Prot
KEGG Report rno:65192 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93337 IMAGE-MGC_LOAD
NCBI Gene 65192 ENTREZGENE
PANTHER LONG-CHAIN FATTY ACID TRANSPORT PROTEIN UniProtKB/Swiss-Prot
  LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 2 UniProtKB/Swiss-Prot
Pfam AMP-binding UniProtKB/Swiss-Prot
  AMP-binding_C UniProtKB/Swiss-Prot
PhenoGen Slc27a2 PhenoGen
PROSITE AMP_BINDING UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000010128 RatGTEx
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/Swiss-Prot
UniProt D3ZSL9 ENTREZGENE
  P97524 ENTREZGENE
  Q66HN6 ENTREZGENE, UniProtKB/TrEMBL
  S27A2_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc27a2  solute carrier family 27 member 2  Slc27a2  solute carrier family 27 (fatty acid transporter), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc27a2  solute carrier family 27 (fatty acid transporter), member 2    solute carrier family 27 (fatty acid transporter), member 32  Name updated 1299863 APPROVED
2002-07-09 Slc27a2  solute carrier family 27 (fatty acid transporter), member 32      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference