Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | diabetic angiopathy | | ISO | RGD:732499 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:25381014 | morbid obesity | | ISO | RGD:732499 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:29311637 | obesity | | ISO | RGD:732499 | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:29311635 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - MGI
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
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Molecular Pathway Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Identification of a specialized adenylyl cyclase that may mediate odorant detection. | Bakalyar HA and Reed RR, Science 1990 Dec 7;250(4986):1403-6. |
| 2. | Non-raft adenylyl cyclase 2 defines a cAMP signaling compartment that selectively regulates IL-6 expression in airway smooth muscle cells: differential regulation of gene expression by AC isoforms. | Bogard AS, etal., Naunyn Schmiedebergs Arch Pharmacol. 2014 Apr;387(4):329-39. doi: 10.1007/s00210-013-0950-4. Epub 2013 Dec 22. |
| 3. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 4. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
| 5. | Rodent oocytes express an active adenylyl cyclase required for meiotic arrest. | Horner K, etal., Dev Biol 2003 Jun 15;258(2):385-96. |
| 6. | Characterization of adenylyl cyclase isoforms in rat peripheral pulmonary arteries. | Jourdan KB, etal., Am J Physiol Lung Cell Mol Physiol. 2001 Jun;280(6):L1359-69. |
| 7. | Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats. | Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. |
| 8. | Inactivation of the mouse adenylyl cyclase 3 gene disrupts male fertility and spermatozoon function. | Livera G, etal., Mol Endocrinol. 2005 May;19(5):1277-90. Epub 2005 Feb 10. |
| 9. | Gene Data Set | MGD Curation, June 12, 2002 |
| 10. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 11. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 12. | Nicotinic acetylcholine receptor alpha 7 regulates cAMP signal within lipid rafts. | Oshikawa J, etal., Am J Physiol Cell Physiol. 2003 Sep;285(3):C567-74. Epub 2003 May 14. |
| 13. | Angiotensin II enhances adenylyl cyclase signaling via Ca2+/calmodulin. Gq-Gs cross-talk regulates collagen production in cardiac fibroblasts. | Ostrom RS, etal., J Biol Chem. 2003 Jul 4;278(27):24461-8. Epub 2003 Apr 23. |
| 14. | A nuclear location for Ca2+-activated adenylyl cyclases I and III in neurones. | Parkinson NA and Bolsover SR, Brain Res Mol Brain Res. 2001 Jul 13;91(1-2):43-9. |
| 15. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
| 16. | PID Annotation Import Pipeline | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 17. | GOA pipeline | RGD automated data pipeline |
| 18. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 19. | Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies. | Sadana R and Dessauer CW, Neurosignals. 2009;17(1):5-22. Epub 2008 Oct 24. |
Additional References at PubMed
| PMID:8889548 | PMID:11055432 | PMID:11549699 | PMID:15499025 | PMID:18596612 | PMID:19946888 | PMID:22179047 | PMID:22531884 | PMID:22871113 | PMID:23018249 | PMID:23077041 | PMID:26393535 |
| PMID:26934374 | PMID:28154160 | PMID:30366013 | PMID:35625651 |
Genomics
Comparative Map Data
| Adcy3 (Rattus norvegicus - Norway rat) |
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| ADCY3 (Homo sapiens - human) |
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| Adcy3 (Mus musculus - house mouse) |
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| Adcy3 (Chinchilla lanigera - long-tailed chinchilla) |
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| ADCY3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ADCY3 (Canis lupus familiaris - dog) |
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| Adcy3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ADCY3 (Sus scrofa - pig) |
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| ADCY3 (Chlorocebus sabaeus - green monkey) |
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| Adcy3 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Adcy3
504 total Variants 
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