Dbnl (drebrin-like) - Rat Genome Database

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Gene: Dbnl (drebrin-like) Rattus norvegicus
Analyze
Symbol: Dbnl
Name: drebrin-like
RGD ID: 70941
Description: A structural constituent of postsynaptic actin cytoskeleton. Involved in postsynaptic actin cytoskeleton organization. Located in dendrite. Is active in glutamatergic synapse; postsynapse; and presynapse. Orthologous to human DBNL (drebrin like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: abp1; actin-binding protein 1; drebrin-like protein; SH3 domain-containing protein 7; Sh3p7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,880,085 - 84,895,122 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1484,880,142 - 84,897,133 (+)EnsemblGRCr8
mRatBN7.21480,666,115 - 80,681,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,666,124 - 80,681,155 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,068,401 - 85,083,685 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,308,505 - 86,323,788 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,757,826 - 82,773,110 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,029,335 - 86,044,364 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,029,335 - 86,044,364 (+)Ensemblrn6Rnor6.0
Rnor_5.01486,721,144 - 86,736,173 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41486,450,448 - 86,481,863 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1479,551,079 - 79,566,108 (+)NCBICelera
RGSC_v3.11486,469,592 - 86,484,067 (+)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methoxyethanol  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Brodifacoum  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
ceric oxide  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
decabromodiphenyl ether  (ISO)
dehydroepiandrosterone  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diuron  (EXP,ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
GSK-J4  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
Mesaconitine  (EXP)
methimazole  (EXP)
nickel atom  (ISO)
nitrates  (ISO)
nobiletin  (ISO)
ozone  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (ISO)
pirinixic acid  (EXP,ISO)
progesterone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
thapsigargin  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation. Haeckel A, etal., J Neurosci. 2008 Oct 1;28(40):10031-44. doi: 10.1523/JNEUROSCI.0336-08.2008.
3. Gene Data Set MGD Curation, June 12, 2002
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family. Qualmann B, etal., J Neurosci. 2004 Mar 10;24(10):2481-95.
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Molecular cloning and dendritic localization of rat SH3P7. Yamazaki H, etal., Eur J Neurosci 2001 Sep;14(6):998-1008.
Additional References at PubMed
PMID:9630982   PMID:10637315   PMID:12913069   PMID:15489334   PMID:16641100   PMID:19056867   PMID:22303001   PMID:24802081   PMID:25468996   PMID:28235806   PMID:30053369  


Genomics

Comparative Map Data
Dbnl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,880,085 - 84,895,122 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1484,880,142 - 84,897,133 (+)EnsemblGRCr8
mRatBN7.21480,666,115 - 80,681,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,666,124 - 80,681,155 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,068,401 - 85,083,685 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,308,505 - 86,323,788 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,757,826 - 82,773,110 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,029,335 - 86,044,364 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,029,335 - 86,044,364 (+)Ensemblrn6Rnor6.0
Rnor_5.01486,721,144 - 86,736,173 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41486,450,448 - 86,481,863 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1479,551,079 - 79,566,108 (+)NCBICelera
RGSC_v3.11486,469,592 - 86,484,067 (+)NCBI
Cytogenetic Map14q21NCBI
DBNL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,044,702 - 44,069,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,044,628 - 44,069,456 (+)Ensemblhg38GRCh38
GRCh37744,084,301 - 44,109,055 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,050,830 - 44,067,840 (+)NCBIBuild 36Build 36hg18NCBI36
Celera744,182,185 - 44,199,260 (+)NCBICelera
Cytogenetic Map7p13NCBI
HuRef743,969,523 - 43,986,598 (+)NCBIHuRef
CHM1_1744,088,113 - 44,105,189 (+)NCBICHM1_1
T2T-CHM13v2.0744,203,197 - 44,227,954 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,123,733 - 44,140,805 (+)NCBI
Dbnl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,730,233 - 5,750,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,738,488 - 5,750,962 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38115,788,483 - 5,800,980 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,788,488 - 5,800,962 (+)Ensemblmm10GRCm38
MGSCv37115,688,486 - 5,700,983 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36115,688,533 - 5,700,965 (+)NCBIMGSCv36mm8
Celera116,278,834 - 6,291,141 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.87NCBI
Dbnl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,912,827 - 7,924,787 (-)Ensembl
ChiLan1.0NW_0049554567,912,827 - 7,924,373 (-)NCBIChiLan1.0ChiLan1.0
DBNL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2648,950,223 - 48,972,891 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,276,140 - 97,297,574 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,753,062 - 44,775,717 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,824,537 - 44,842,059 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,824,608 - 44,845,891 (+)EnsemblpanPan2panpan1.1
DBNL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha161,996,510 - 2,007,305 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01614,854,694 - 14,865,499 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,854,694 - 14,877,271 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,485,876 - 14,496,666 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,466,360 - 14,477,156 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dbnl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,795,888 - 99,809,337 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,007,672 - 19,020,361 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,007,630 - 19,021,068 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DBNL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,713,340 - 48,725,697 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11848,713,335 - 48,725,692 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21853,426,424 - 53,438,753 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DBNL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,610,196 - 14,627,363 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,608,571 - 14,627,321 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dbnl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,950,556 - 7,960,568 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247407,950,552 - 7,960,592 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dbnl
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11174,746,968 - 74,761,517 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dbnl
317 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:293
Count of miRNA genes:183
Interacting mature miRNAs:201
Transcripts:ENSRNOT00000017375
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat

Markers in Region
D14Mgh1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81484,898,800 - 84,898,905 (+)Marker Load Pipeline
mRatBN7.21480,684,833 - 80,684,938 (+)MAPPERmRatBN7.2
Rnor_6.01486,048,043 - 86,048,147NCBIRnor6.0
Rnor_5.01486,739,852 - 86,739,956UniSTSRnor5.0
RGSC_v3.41486,469,093 - 86,469,197UniSTSRGSC3.4
Celera1479,569,638 - 79,569,742UniSTS
RH 3.4 Map14571.5UniSTS
RH 3.4 Map14571.5RGD
RH 2.0 Map14702.9RGD
SHRSP x BN Map1444.8999RGD
Cytogenetic Map14q21UniSTS
Cytogenetic Map14q21-q22UniSTS
D14Rat19  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81484,898,287 - 84,898,449 (+)Marker Load Pipeline
mRatBN7.21480,684,320 - 80,684,482 (+)MAPPERmRatBN7.2
Rnor_6.01486,047,530 - 86,047,691NCBIRnor6.0
Rnor_5.01486,739,339 - 86,739,500UniSTSRnor5.0
RGSC_v3.41486,468,580 - 86,468,741UniSTSRGSC3.4
RGSC_v3.41486,468,542 - 86,468,937RGDRGSC3.4
RGSC_v3.11486,487,725 - 86,487,886RGD
RH 3.4 Map14571.5RGD
RH 3.4 Map14571.5UniSTS
RH 2.0 Map14702.7RGD
SHRSP x BN Map1445.38RGD
Cytogenetic Map14q21-q22UniSTS
Cytogenetic Map14q21UniSTS
AW532217  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,690,859 - 80,690,958 (+)MAPPERmRatBN7.2
Rnor_6.01486,054,068 - 86,054,166NCBIRnor6.0
Rnor_5.01486,745,877 - 86,745,975UniSTSRnor5.0
RGSC_v3.41486,475,118 - 86,475,216UniSTSRGSC3.4
Celera1479,575,631 - 79,575,729UniSTS
RH 3.4 Map14572.7UniSTS
Cytogenetic Map14q21UniSTS
AW527377  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,682,949 - 80,683,113 (+)MAPPERmRatBN7.2
Rnor_6.01486,046,159 - 86,046,322NCBIRnor6.0
Rnor_5.01486,737,968 - 86,738,131UniSTSRnor5.0
RGSC_v3.41486,467,209 - 86,467,372UniSTSRGSC3.4
Celera1479,567,903 - 79,568,066UniSTS
RH 3.4 Map14571.5UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map14q21-q22UniSTS
AI713198  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,680,929 - 80,681,084 (+)MAPPERmRatBN7.2
Rnor_6.01486,044,139 - 86,044,293NCBIRnor6.0
Rnor_5.01486,735,948 - 86,736,102UniSTSRnor5.0
RGSC_v3.41486,465,189 - 86,465,343UniSTSRGSC3.4
Celera1479,565,883 - 79,566,037UniSTS
RH 3.4 Map14573.2UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001277211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001277212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001277213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB009346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB038364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB038365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC128636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC072483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000017375   ⟹   ENSRNOP00000017375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1484,880,142 - 84,895,110 (+)Ensembl
mRatBN7.2 Ensembl1480,666,124 - 80,681,155 (+)Ensembl
Rnor_6.0 Ensembl1486,029,335 - 86,044,364 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000130668   ⟹   ENSRNOP00000101080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1484,880,142 - 84,897,133 (+)Ensembl
RefSeq Acc Id: NM_001277211   ⟹   NP_001264140
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,093 - 84,895,122 (+)NCBI
mRatBN7.21480,666,124 - 80,681,155 (+)NCBI
Rnor_6.01486,029,335 - 86,044,364 (+)NCBI
Rnor_5.01486,721,144 - 86,736,173 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001277212   ⟹   NP_001264141
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,093 - 84,895,122 (+)NCBI
mRatBN7.21480,666,124 - 80,681,155 (+)NCBI
Rnor_6.01486,029,335 - 86,044,364 (+)NCBI
Rnor_5.01486,721,144 - 86,736,173 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001277213   ⟹   NP_001264142
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,093 - 84,895,122 (+)NCBI
mRatBN7.21480,666,124 - 80,681,155 (+)NCBI
Rnor_6.01486,029,335 - 86,044,364 (+)NCBI
Rnor_5.01486,721,144 - 86,736,173 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBI
Sequence:
RefSeq Acc Id: NM_031352   ⟹   NP_112642
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,093 - 84,895,122 (+)NCBI
mRatBN7.21480,666,124 - 80,681,155 (+)NCBI
Rnor_6.01486,029,335 - 86,044,364 (+)NCBI
Rnor_5.01486,721,144 - 86,736,173 (+)NCBI
RGSC_v3.41486,450,448 - 86,481,863 (+)RGD
Celera1479,551,079 - 79,566,108 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092499   ⟹   XP_038948427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,085 - 84,892,065 (+)NCBI
mRatBN7.21480,666,115 - 80,678,024 (+)NCBI
RefSeq Acc Id: XM_039092500   ⟹   XP_038948428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,085 - 84,892,065 (+)NCBI
mRatBN7.21480,666,115 - 80,678,024 (+)NCBI
RefSeq Acc Id: XM_039092501   ⟹   XP_038948429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,085 - 84,892,065 (+)NCBI
mRatBN7.21480,666,115 - 80,678,024 (+)NCBI
RefSeq Acc Id: NP_112642   ⟸   NM_031352
- Peptide Label: isoform 2
- UniProtKB: A6IKP2 (UniProtKB/TrEMBL),   A6IKP5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264140   ⟸   NM_001277211
- Peptide Label: isoform 1
- UniProtKB: Q9JM67 (UniProtKB/Swiss-Prot),   Q9JM66 (UniProtKB/Swiss-Prot),   Q9JM74 (UniProtKB/Swiss-Prot),   Q9JHL4 (UniProtKB/Swiss-Prot),   A6IKP5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264141   ⟸   NM_001277212
- Peptide Label: isoform 3
- UniProtKB: A6IKP5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264142   ⟸   NM_001277213
- Peptide Label: isoform 4
- UniProtKB: A6IKP5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017375   ⟸   ENSRNOT00000017375
RefSeq Acc Id: XP_038948427   ⟸   XM_039092499
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038948428   ⟸   XM_039092500
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038948429   ⟸   XM_039092501
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000101080   ⟸   ENSRNOT00000130668
Protein Domains
ADF-H   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JHL4-F1-model_v2 AlphaFold Q9JHL4 1-436 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699461
Promoter ID:EPDNEW_R9985
Type:initiation region
Name:Dbnl_1
Description:drebrin-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,029,375 - 86,029,435EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70941 AgrOrtholog
BioCyc Gene G2FUF-15127 BioCyc
Ensembl Genes ENSRNOG00000012378 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017375.8 UniProtKB/Swiss-Prot
  ENSRNOT00000130668 ENTREZGENE
Gene3D-CATH 3.40.20.10 UniProtKB/Swiss-Prot
  SH3 Domains UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7104722 IMAGE-MGC_LOAD
InterPro ADF-H UniProtKB/Swiss-Prot
  ADF-H/Gelsolin-like_dom_sf UniProtKB/Swiss-Prot
  Drebrin-like_SH3 UniProtKB/Swiss-Prot
  SH3-like_dom_sf UniProtKB/Swiss-Prot
  SH3_domain UniProtKB/Swiss-Prot
KEGG Report rno:83527 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91641 IMAGE-MGC_LOAD
NCBI Gene 83527 ENTREZGENE
PANTHER CORTACTIN AND DREBRIN UniProtKB/Swiss-Prot
  PTHR10829:SF12 UniProtKB/Swiss-Prot
Pfam Cofilin_ADF UniProtKB/Swiss-Prot
  SH3_9 UniProtKB/Swiss-Prot
PhenoGen Dbnl PhenoGen
PROSITE ADF_H UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012378 RatGTEx
SMART ADF UniProtKB/Swiss-Prot
  SH3 UniProtKB/Swiss-Prot
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/Swiss-Prot
  SSF50044 UniProtKB/Swiss-Prot
UniProt A6IKP2 ENTREZGENE, UniProtKB/TrEMBL
  A6IKP3_RAT UniProtKB/TrEMBL
  A6IKP4_RAT UniProtKB/TrEMBL
  A6IKP5 ENTREZGENE, UniProtKB/TrEMBL
  DBNL_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JM66 ENTREZGENE
  Q9JM67 ENTREZGENE
  Q9JM74 ENTREZGENE
UniProt Secondary Q9JM66 UniProtKB/Swiss-Prot
  Q9JM67 UniProtKB/Swiss-Prot
  Q9JM74 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Dbnl  drebrin-like      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains a drebrin homology sequence and a cortactin homology sequence (SH3 domain) 70709