Dbnl (drebrin-like) - Rat Genome Database

Name: Dbnl
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Dbnl (drebrin-like) Rattus norvegicus

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Symbol:

Dbnl

Name:

drebrin-like

RGD ID:

70941

Description:

A structural constituent of postsynaptic actin cytoskeleton. Involved in postsynaptic actin cytoskeleton organization. Located in dendrite. Is active in glutamatergic synapse; postsynapse; and presynapse. Orthologous to human DBNL (drebrin like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

abp1; actin-binding protein 1; drebrin-like protein; SH3 domain-containing protein 7; Sh3p7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DBNL (drebrin like)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Dbnl (drebrin-like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dbnl (drebrin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DBNL (drebrin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DBNL (drebrin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dbnl (drebrin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DBNL (drebrin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DBNL (drebrin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dbnl (drebrin like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Dbnl (drebrin-like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	DBNL (drebrin like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dbnla (drebrin-like a)	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	dbnlb (drebrin-like b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Abp1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ABP1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	dbn-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dbnl	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	84,880,085 - 84,895,122 (+)	NCBI		GRCr8
mRatBN7.2	14	80,666,115 - 80,681,155 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	80,666,124 - 80,681,155 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	85,068,401 - 85,083,685 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	86,308,505 - 86,323,788 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	82,757,826 - 82,773,110 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	86,029,335 - 86,044,364 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	86,029,335 - 86,044,364 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	86,721,144 - 86,736,173 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	86,450,448 - 86,481,863 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	86,469,592 - 86,484,067 (+)	NCBI
Celera	14	79,551,079 - 79,566,108 (+)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Dimauro Disease (ISO)

genetic disease (ISO)

pleomorphic xanthoastrocytoma (ISO)

Rhabdomyolysis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methoxyethanol (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (ISO)

amitrole (EXP)

ammonium chloride (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

Brodifacoum (EXP)

caffeine (ISO)

carbon nanotube (ISO)

ceric oxide (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

coumarin (ISO)

crocidolite asbestos (ISO)

decabromodiphenyl ether (ISO)

dehydroepiandrosterone (EXP)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

diuron (EXP,ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

hexadecanoic acid (ISO)

hydrogen peroxide (ISO)

ivermectin (ISO)

lead(0) (ISO)

Mesaconitine (EXP)

methimazole (EXP)

nickel atom (ISO)

ozone (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (EXP,ISO)

progesterone (ISO)

SB 431542 (ISO)

sulfadimethoxine (EXP)

thapsigargin (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin filament bundle assembly (ISO)

actin filament severing (ISO)

adaptive immune response (IEA)

barbed-end actin filament capping (ISO)

endocytosis (IEA)

neuron projection morphogenesis (IBA,ISO,ISS)

podosome assembly (ISO,ISS)

positive regulation of axon extension (IBA)

positive regulation of dendritic spine morphogenesis (IBA)

postsynaptic actin cytoskeleton organization (IBA,IDA,IMP)

Rac protein signal transduction (ISO,ISS)

regulation of actin filament polymerization (IBA)

synapse assembly (ISO,ISS)

Cellular Component

actin filament (IBA)

anchoring junction (IEA)

cell cortex (ISO,ISS)

clathrin-coated vesicle membrane (IEA)

cortical actin cytoskeleton (IBA)

cytoplasm (ISO,ISS)

cytosol (IEA)

dendrite (IBA,IDA)

early endosome (IEA)

glutamatergic synapse (IDA,IMP)

Golgi membrane (IEA)

intracellular membrane-bounded organelle (ISO)

lamellipodium (IBA,ISO,ISS)

perikaryon (IEA)

plasma membrane (ISO)

podosome (ISO,ISS)

postsynapse (IDA)

postsynaptic density (IBA)

postsynaptic membrane (IBA)

presynapse (IDA)

ruffle (ISO,ISS)

site of polarized growth (IBA)

Molecular Function

actin binding (ISO,ISS,TAS)

actin filament binding (IBA,ISO,ISS)

protein binding (IPI,ISO)

protein domain specific binding (ISO)

structural constituent of postsynaptic actin cytoskeleton (IDA,IMP)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation.	Haeckel A, etal., J Neurosci. 2008 Oct 1;28(40):10031-44. doi: 10.1523/JNEUROSCI.0336-08.2008.
3.	Gene Data Set	MGD Curation, June 12, 2002
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family.	Qualmann B, etal., J Neurosci. 2004 Mar 10;24(10):2481-95.
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10.	Molecular cloning and dendritic localization of rat SH3P7.	Yamazaki H, etal., Eur J Neurosci 2001 Sep;14(6):998-1008.

Additional References at PubMed

PMID:9630982	PMID:10637315	PMID:12913069	PMID:15489334	PMID:16641100	PMID:19056867	PMID:22303001	PMID:24802081	PMID:25468996	PMID:28235806	PMID:30053369

Genomics

Comparative Map Data

Dbnl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	84,880,085 - 84,895,122 (+)	NCBI		GRCr8
mRatBN7.2	14	80,666,115 - 80,681,155 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	80,666,124 - 80,681,155 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	85,068,401 - 85,083,685 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	86,308,505 - 86,323,788 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	82,757,826 - 82,773,110 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	86,029,335 - 86,044,364 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	86,029,335 - 86,044,364 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	86,721,144 - 86,736,173 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	86,450,448 - 86,481,863 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	86,469,592 - 86,484,067 (+)	NCBI
Celera	14	79,551,079 - 79,566,108 (+)	NCBI		Celera
Cytogenetic Map	14	q21	NCBI

DBNL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	44,044,702 - 44,069,456 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	44,044,640 - 44,069,456 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	44,084,301 - 44,109,055 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	44,050,830 - 44,067,840 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	44,182,185 - 44,199,260 (+)	NCBI		Celera
Cytogenetic Map	7	p13	NCBI
HuRef	7	43,969,523 - 43,986,598 (+)	NCBI		HuRef
CHM1_1	7	44,088,113 - 44,105,189 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	44,203,197 - 44,227,954 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	44,123,733 - 44,140,805 (+)	NCBI

Dbnl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	5,730,233 - 5,750,980 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	5,738,488 - 5,750,962 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	5,788,483 - 5,800,980 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	5,788,488 - 5,800,962 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	5,688,486 - 5,700,983 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	5,688,533 - 5,700,965 (+)	NCBI		MGSCv36	mm8
Celera	11	6,278,834 - 6,291,141 (+)	NCBI		Celera
Cytogenetic Map	11	A1	NCBI
cM Map	11	3.87	NCBI

Dbnl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955456	7,912,827 - 7,924,787 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955456	7,912,827 - 7,924,373 (-)	NCBI	ChiLan1.0	ChiLan1.0

DBNL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	48,950,223 - 48,972,891 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	97,276,140 - 97,297,574 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	44,753,062 - 44,775,717 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	44,824,537 - 44,842,059 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	44,824,608 - 44,845,891 (+)	Ensembl	panpan1.1		panPan2

DBNL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Dog10K_Boxer_Tasha	16	1,996,510 - 2,007,305 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	16	14,854,694 - 14,865,499 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	16	14,854,694 - 14,877,271 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.0	16	14,485,876 - 14,496,666 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	16	14,466,360 - 14,477,156 (-)	NCBI		UU_Cfam_GSD_1.0

Dbnl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	99,795,888 - 99,809,337 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	19,007,672 - 19,020,361 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	19,007,630 - 19,021,068 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DBNL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	48,713,340 - 48,725,697 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	48,713,335 - 48,725,692 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	53,426,424 - 53,438,753 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DBNL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	14,610,196 - 14,627,363 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	14,608,571 - 14,627,321 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666062	7,886,798 - 7,904,467 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dbnl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	7,950,556 - 7,960,568 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624740	7,950,552 - 7,960,592 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Dbnl
67 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	293
Count of miRNA genes:	183
Interacting mature miRNAs:	201
Transcripts:	ENSRNOT00000017375
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313089	Bss81	Bone structure and strength QTL 81	3.4	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	14	37669719	82669719	Rat
9590294	Uminl4	Urine mineral level QTL 4	5.66	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	14	55624247	100624247	Rat
1582236	Gluco22	Glucose level QTL 22	3.3	0.0164	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	92554092	Rat
631213	Bw60	Body weight QTL60	4.51		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	14	79950921	95876975	Rat
2300197	Scl59	Serum cholesterol level QTL 59			blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	55147478	100147478	Rat
70153	Bp59	Blood pressure QTL 59	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	14	68757796	83368335	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30320092	80829842	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	40793460	98037301	Rat
1582259	Gluco23	Glucose level QTL 23	3.1	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	70053989	104886043	Rat
1582197	Gluco27	Glucose level QTL 27	3.4	0.0006	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	73415323	92554092	Rat
2313100	Bss82	Bone structure and strength QTL 82	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	14	37669719	82669719	Rat
634328	Hc5	Hypercalciuria QTL 5	2.3		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	14	58184885	103184885	Rat
1582250	Gluco26	Glucose level QTL 26	3.3	0.0009	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	95876975	Rat
2317879	Alcrsp27	Alcohol response QTL 27	3.3	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	14	56631369	101631369	Rat
1641900	Alcrsp11	Alcohol response QTL 11			alcohol metabolism trait (VT:0015089)	blood ethanol level (CMO:0000535)	14	70053989	104886043	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	95876975	Rat
1582255	Gluco29	Glucose level QTL 29	3.1	0.0025	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	14	73415323	92554092	Rat
9589034	Epfw11	Epididymal fat weight QTL 11	6	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	14	55624247	100624247	Rat
1582209	Gluco20	Glucose level QTL 20	3.8	0.0005	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	73415323	92554092	Rat
2313048	Bss84	Bone structure and strength QTL 84	3.1	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	14	37669719	82669719	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42262529	95023211	Rat
1549834	Scl45	Serum cholesterol level QTL 45	5.8		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	14	50023211	95023211	Rat
738037	Hcas6	Hepatocarcinoma susceptibility QTL 6	2.93		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	14	39057237	83368335	Rat
2313084	Bss83	Bone structure and strength QTL 83	2.9	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	14	37669719	82669719	Rat

Markers in Region

D14Mgh1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	80,684,833 - 80,684,938 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	86,048,043 - 86,048,147	NCBI	Rnor6.0
Rnor_5.0	14	86,739,852 - 86,739,956	UniSTS	Rnor5.0
RGSC_v3.4	14	86,469,093 - 86,469,197	UniSTS	RGSC3.4
Celera	14	79,569,638 - 79,569,742	UniSTS
RH 3.4 Map	14	571.5	UniSTS
RH 3.4 Map	14	571.5	RGD
RH 2.0 Map	14	702.9	RGD
SHRSP x BN Map	14	44.8999	RGD
Cytogenetic Map	14	q21	UniSTS
Cytogenetic Map	14	q21-q22	UniSTS

D14Rat19

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	80,684,320 - 80,684,482 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	86,047,530 - 86,047,691	NCBI	Rnor6.0
Rnor_5.0	14	86,739,339 - 86,739,500	UniSTS	Rnor5.0
RGSC_v3.4	14	86,468,542 - 86,468,937	RGD	RGSC3.4
RGSC_v3.4	14	86,468,580 - 86,468,741	UniSTS	RGSC3.4
RGSC_v3.1	14	86,487,725 - 86,487,886	RGD
RH 3.4 Map	14	571.5	RGD
RH 3.4 Map	14	571.5	UniSTS
RH 2.0 Map	14	702.7	RGD
SHRSP x BN Map	14	45.38	RGD
Cytogenetic Map	14	q21-q22	UniSTS
Cytogenetic Map	14	q21	UniSTS

AW532217

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	80,690,859 - 80,690,958 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	86,054,068 - 86,054,166	NCBI	Rnor6.0
Rnor_5.0	14	86,745,877 - 86,745,975	UniSTS	Rnor5.0
RGSC_v3.4	14	86,475,118 - 86,475,216	UniSTS	RGSC3.4
Celera	14	79,575,631 - 79,575,729	UniSTS
RH 3.4 Map	14	572.7	UniSTS
Cytogenetic Map	14	q21	UniSTS

AW527377

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	80,682,949 - 80,683,113 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	86,046,159 - 86,046,322	NCBI	Rnor6.0
Rnor_5.0	14	86,737,968 - 86,738,131	UniSTS	Rnor5.0
RGSC_v3.4	14	86,467,209 - 86,467,372	UniSTS	RGSC3.4
Celera	14	79,567,903 - 79,568,066	UniSTS
RH 3.4 Map	14	571.5	UniSTS
Cytogenetic Map	14	q21	UniSTS
Cytogenetic Map	14	q21-q22	UniSTS

AI713198

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	80,680,929 - 80,681,084 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	86,044,139 - 86,044,293	NCBI	Rnor6.0
Rnor_5.0	14	86,735,948 - 86,736,102	UniSTS	Rnor5.0
RGSC_v3.4	14	86,465,189 - 86,465,343	UniSTS	RGSC3.4
Celera	14	79,565,883 - 79,566,037	UniSTS
RH 3.4 Map	14	573.2	UniSTS
Cytogenetic Map	14	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001277211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001277212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001277213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_031352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB009346	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB038364	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB038365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB039818	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB039819	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC128636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC072483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ228854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000017375 ⟹ ENSRNOP00000017375

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	80,666,124 - 80,681,155 (+)	Ensembl
Rnor_6.0 Ensembl	14	86,029,335 - 86,044,364 (+)	Ensembl

RefSeq Acc Id:

NM_001277211 ⟹ NP_001264140

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	84,880,093 - 84,895,122 (+)	NCBI
mRatBN7.2	14	80,666,124 - 80,681,155 (+)	NCBI
Rnor_6.0	14	86,029,335 - 86,044,364 (+)	NCBI
Rnor_5.0	14	86,721,144 - 86,736,173 (+)	NCBI
Celera	14	79,551,079 - 79,566,108 (+)	NCBI

Sequence:

show sequence

TTCCGTCCGTCACTGGAGGCCGGCAGAAAGCTGAGGCTGCATCATTGCTGAGACCGTGGGGCGT
GACATGGCGGTGAACCTGAGCCGGAACGGGCCGGCGCTGCAGGAGGCCTATGTGCGGGTGGTCA
CCGAGAAATCCCCGACCGACTGGGCTCTTTTTACCTATGAAGGCAACAGCAATGACATCCGTGT
GGCTGGCACAGGGGAGGGAGGCCTGGAGGAGCTGGTGGAGGAGCTCAACAGCGGGAAGGTGATG
TACGCCTTCTGCAGGGTGAAGGACCCCAACTCTGGCCTGCCCAAGTTTGTCCTCATCAACTGGA
CAGGCGAGGGTGTGAATGATGTGCGAAAAGGAGCATGTGCCAACCACGTCAGCACCATGGCCAA
CTTCCTAAAGGGTGCCCATGTGACCATCAACGCACGGGCTGAGGAAGATGTGGAGCCTGAGTGC
ATCATGGAGAAGGTTGCCAAGGCTTCTGGGGCTAATTACAGCTTCCATAAGGAAAGCAGCTGCT
TCCAGGATGTGGGGCCTCAGGCCCCAGTGGGCTCTGTGTACCAGAAGACCAATGCCGTGTCTGA
GATCAAGAGAGTTGGCAAGGATAACTTCTGGGCCAAAGCTGAGAAGGAGGAGGAGAACCGCCGC
CTGGAGGAGAAGCGGCGGGCTGAAGAGGAGAAGCAGCGGCTGGAGGAGGAGCGGCGGGAGCGGG
AGCTGCAGGAGGCTGCCCGACGGGAACAACGCTACCAGGAACAGCACAGATCAGCTGGACCCCC
AAGCCCTTCCAGCAGGACAGGTGAACTGGAGCAAGAGGTGGTTTCAAGGAGCAGACAGGAATGG
GAGTCTGCTGGGCAGCAGGCCCCACACCCACGGGAGATTTTCAAGCAGAAGGAAAGGGCTATGT
CCACCACCTCTGTCTCCAGCTCTCAGCCAGGCAAGCTGAGGAGCCCCTTCCTGCAGAAGCAGTT
CACTCAACCAGAAGCTTCCTATGGCCGAGAGCCCACTTCTCCTGTGTCACGGCCTGCAGCAGGT
GTCTGCGAGGAGCTGGCACCCAGCACTCCGCCCTCAGCCCAGACAGACGATGAACCTACATATG
AAGTGCCCTCCGAGCAGGAGACCCTGTACGAGGAACCACCACCGGTCCAGCAGCCAGGGGCTGG
CTCCGGACACATTGACAACTACATGCAGAGCCAGGACCTCAGTGGGCAAGGACTGTGCGCTCGG
GCCTTGTACGACTACCAGGCAGCTGACGACACGGAGATCTCCTTTGACCCTGAGAACCTAATCA
CAGGCATCGAGGTGATTGACGAAGGCTGGTGGCGTGGCTATGGGCCTGACGGCCACTTTGGCAT
GTTTCCTGCCAACTATGTGGAGCTCATAGAGTGAGCGAGGTCTGTTGTCCTTCTCTACCACAAG
TGGCTTCCTTGTTGCCTAAGAGTTAATGTTCGGCACTGTTCCAGAAATGGGACTTGAGTGAGGA
CAAGGCTTCCTCTGCCCTGAGTGCTCCTGTTACCCCAGATATAGCAGCTCCCACTGCTCCCCCA
AATGCTTACCGCAGCCTCTAGGCCCTTCTGCCAGCCTTACACTTGACTCCAGTGGGAATGGCAT
ACTGAGCCAGGCTTAACCTGTGACCAGCTCTGGATGGCCTCTGTCCAGGGACATCCGCACTGAG
ACATTGGACATCCGGGGCCACACTGTACATTTGTCTGTCTTTCTGTGTGGCTTCTAAGGGCAGC
AGCTGCAGCTGTTTAGAAAAGCTCTTGGAGATCATGAACTTAAAAGAGAATTGCTTTCAGTGAA
ATCTTGACCAAAGTCAGAGTAGACCTTGACGGTTCTGACAGCAGGGAGGTTTTCTTACCGGAGG
CTTCCCTCCTTTCCTATCCCTGTGTCTGTGCTGTGGGAAGGGGGGCTGGGATGAGCAAGCTTCC
GTCTCTGGGAATGTGCAAAGTCAAAGACATGCGTCATGTGGTTCATCTGGTGCGTCCTATACCC
TGGCTCCGCCCCTCTGGTGGATGAGTCTAAGCCGTGTGGTGAGGCCCACAGCCCATCTGCCCCA
CTGTGACCTGAGTGGGGAAGAAGTCTAAGCCCACACCACACCTGAGCGTGCACACGTGTGTCAG
ACTGTGTAGCCTCCTCCAGGAAGCATAAGTGAGCAGGAATGGTAGCTAGCTCATGGCTGCACTC
ACGAGGGAGAGGCAGAGGCAGGTGGGTCTCTGAGTTCAAGGCCACAAGCCCAGCCTGGTCTTCA
CTGTTCCTGGACAGCCAGGGTTAACAGGGGTATAAATGATATAACTGATGTTGGA

hide sequence

RefSeq Acc Id:

NM_001277212 ⟹ NP_001264141

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	84,880,093 - 84,895,122 (+)	NCBI
mRatBN7.2	14	80,666,124 - 80,681,155 (+)	NCBI
Rnor_6.0	14	86,029,335 - 86,044,364 (+)	NCBI
Rnor_5.0	14	86,721,144 - 86,736,173 (+)	NCBI
Celera	14	79,551,079 - 79,566,108 (+)	NCBI

Sequence:

show sequence

TTCCGTCCGTCACTGGAGGCCGGCAGAAAGCTGAGGCTGCATCATTGCTGAGACCGTGGGGCGT
GACATGGCGGTGAACCTGAGCCGGAACGGGCCGGCGCTGCAGGAGGCCTATGTGCGGGTGGTCA
CCGAGAAATCCCCGACCGACTGGGCTCTTTTTACCTATGAAGGCAACAGCAATGACATCCGTGT
GGCTGGCACAGGGGAGGGAGGCCTGGAGGAGCTGGTGGAGGAGCTCAACAGCGGGAAGGTGATG
TACGCCTTCTGCAGGGTGAAGGACCCCAACTCTGGCCTGCCCAAGTTTGTCCTCATCAACTGGA
CAGGCGAGGGTGTGAATGATGTGCGAAAAGGAGCATGTGCCAACCACGTCAGCACCATGGCCAA
CTTCCTAAAGGGTGCCCATGTGACCATCAACGCACGGGCTGAGGAAGATGTGGAGCCTGAGTGC
ATCATGGAGAAGGTTGCCAAGGCTTCTGGGGCTAATTACAGCTTCCATAAGGAAAGCAGCTGCT
TCCAGGATGTGGGGCCTCAGGCCCCAGTGGGCTCTGTGTACCAGAAGACCAATGCCGTGTCTGA
GATCAAGAGAGTTGGCAAGGATAACTTCTGGGCCAAAGCTGAGAAGGAGGAGGAGAACCGCCGC
CTGGAGGAGAAGCGGCGGGCTGAAGAGGAGAAGCAGCGGCTGGAGGAGGAGCGGCGGGAGCGGG
AGCTGCAGGAGGCTGCCCGACGGGAACAACGCTACCAGGAACAGCACAGATCAGCTGGACCCCC
AAGGACAGGTGAACTGGAGCAAGAGGTGGTTTCAAGGAGCAGACAGGAATGGGAGTCTGCTGGG
CAGCAGGCCCCACACCCACGGGAGATTTTCAAGCAGAAGGAAAGGGCTATGTCCACCACCTCTG
TCTCCAGCTCTCAGCCAGGCAAGCTGAGGAGCCCCTTCCTGCAGAAGCAGTTCACTCAACCAGA
AGCTTCCTATGGCCGAGAGCCCACTTCTCCTGTGTCACGGCCTGCAGCAGGTGTCTGCGAGGAG
CTGGCACCCAGCACTCCGCCCTCAGCCCAGACAGACGATGAACCTACATATGAAGTGCCCTCCG
AGCAGGAGACCCTGTACGAGGAACCACCACCGGTCCAGCAGCCAGGGGCTGGCTCCGGACACAT
TGACAACTACATGCAGAGCCAGGACCTCAGTGGGCAAGGACTGTGCGCTCGGGCCTTGTACGAC
TACCAGGCAGCTGACGACACGGAGATCTCCTTTGACCCTGAGAACCTAATCACAGGCATCGAGG
TGATTGACGAAGGCTGGTGGCGTGGCTATGGGCCTGACGGCCACTTTGGCATGTTTCCTGCCAA
CTATGTGGAGCTCATAGAGTGAGCGAGGTCTGTTGTCCTTCTCTACCACAAGTGGCTTCCTTGT
TGCCTAAGAGTTAATGTTCGGCACTGTTCCAGAAATGGGACTTGAGTGAGGACAAGGCTTCCTC
TGCCCTGAGTGCTCCTGTTACCCCAGATATAGCAGCTCCCACTGCTCCCCCAAATGCTTACCGC
AGCCTCTAGGCCCTTCTGCCAGCCTTACACTTGACTCCAGTGGGAATGGCATACTGAGCCAGGC
TTAACCTGTGACCAGCTCTGGATGGCCTCTGTCCAGGGACATCCGCACTGAGACATTGGACATC
CGGGGCCACACTGTACATTTGTCTGTCTTTCTGTGTGGCTTCTAAGGGCAGCAGCTGCAGCTGT
TTAGAAAAGCTCTTGGAGATCATGAACTTAAAAGAGAATTGCTTTCAGTGAAATCTTGACCAAA
GTCAGAGTAGACCTTGACGGTTCTGACAGCAGGGAGGTTTTCTTACCGGAGGCTTCCCTCCTTT
CCTATCCCTGTGTCTGTGCTGTGGGAAGGGGGGCTGGGATGAGCAAGCTTCCGTCTCTGGGAAT
GTGCAAAGTCAAAGACATGCGTCATGTGGTTCATCTGGTGCGTCCTATACCCTGGCTCCGCCCC
TCTGGTGGATGAGTCTAAGCCGTGTGGTGAGGCCCACAGCCCATCTGCCCCACTGTGACCTGAG
TGGGGAAGAAGTCTAAGCCCACACCACACCTGAGCGTGCACACGTGTGTCAGACTGTGTAGCCT
CCTCCAGGAAGCATAAGTGAGCAGGAATGGTAGCTAGCTCATGGCTGCACTCACGAGGGAGAGG
CAGAGGCAGGTGGGTCTCTGAGTTCAAGGCCACAAGCCCAGCCTGGTCTTCACTGTTCCTGGAC
AGCCAGGGTTAACAGGGGTATAAATGATATAACTGATGTTGGA

hide sequence

RefSeq Acc Id:

NM_001277213 ⟹ NP_001264142

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	84,880,093 - 84,895,122 (+)	NCBI
mRatBN7.2	14	80,666,124 - 80,681,155 (+)	NCBI
Rnor_6.0	14	86,029,335 - 86,044,364 (+)	NCBI
Rnor_5.0	14	86,721,144 - 86,736,173 (+)	NCBI
Celera	14	79,551,079 - 79,566,108 (+)	NCBI

Sequence:

show sequence

TTCCGTCCGTCACTGGAGGCCGGCAGAAAGCTGAGGCTGCATCATTGCTGAGACCGTGGGGCGT
GACATGGCGGTGAACCTGAGCCGGAACGGGCCGGCGCTGCAGGAGGCCTATGTGCGGGTGGTCA
CCGAGAAATCCCCGACCGACTGGGCTCTTTTTACCTATGAAGGCAACAGCAATGACATCCGTGT
GGCTGGCACAGGGGAGGGAGGCCTGGAGGAGCTGGTGGAGGAGCTCAACAGCGGGAAGGTGATG
TACGCCTTCTGCAGGGTGAAGGACCCCAACTCTGGCCTGCCCAAGTTTGTCCTCATCAACTGGA
CAGGCGAGGGTGTGAATGATGTGCGAAAAGGAGCATGTGCCAACCACGTCAGCACCATGGCCAA
CTTCCTAAAGGGTGCCCATGTGACCATCAACGCACGGGCTGAGGAAGATGTGGAGCCTGAGTGC
ATCATGGAGAAGGTTGCCAAGGCTTCTGGGGCTAATTACAGCTTCCATAAGGAAAGCAGCTGCT
TCCAGGATGTGGGGCCTCAGGCCCCAGTGGGCTCTGTGTACCAGAAGACCAATGCCGTGTCTGA
GATCAAGAGAGTTGGCAAGGATAACTTCTGGGCCAAAGCTGAGAAGGAGGAGGAGAACCGCCGC
CTGGAGGAGAAGCGGCGGGCTGAAGAGGAGAAGCAGCGGCTGGAGGAGGAGCGGCGGGAGCGGG
AGCTGCAGGAGGCTGCCCGACGGGAACAACGCTACCAGGAACAGCACAGATCAGCTGGACCCCC
AAGGACAGGTGAACTGGAGCAAGAGGTGGTTTCAAGGAGCAGACAGGAATGGTCTGCTGGGCAG
CAGGCCCCACACCCACGGGAGATTTTCAAGCAGAAGGAAAGGGCTATGTCCACCACCTCTGTCT
CCAGCTCTCAGCCAGGCAAGCTGAGGAGCCCCTTCCTGCAGAAGCAGTTCACTCAACCAGAAGC
TTCCTATGGCCGAGAGCCCACTTCTCCTGTGTCACGGCCTGCAGCAGGTGTCTGCGAGGAGCTG
GCACCCAGCACTCCGCCCTCAGCCCAGACAGACGATGAACCTACATATGAAGTGCCCTCCGAGC
AGGAGACCCTGTACGAGGAACCACCACCGGTCCAGCAGCCAGGGGCTGGCTCCGGACACATTGA
CAACTACATGCAGAGCCAGGACCTCAGTGGGCAAGGACTGTGCGCTCGGGCCTTGTACGACTAC
CAGGCAGCTGACGACACGGAGATCTCCTTTGACCCTGAGAACCTAATCACAGGCATCGAGGTGA
TTGACGAAGGCTGGTGGCGTGGCTATGGGCCTGACGGCCACTTTGGCATGTTTCCTGCCAACTA
TGTGGAGCTCATAGAGTGAGCGAGGTCTGTTGTCCTTCTCTACCACAAGTGGCTTCCTTGTTGC
CTAAGAGTTAATGTTCGGCACTGTTCCAGAAATGGGACTTGAGTGAGGACAAGGCTTCCTCTGC
CCTGAGTGCTCCTGTTACCCCAGATATAGCAGCTCCCACTGCTCCCCCAAATGCTTACCGCAGC
CTCTAGGCCCTTCTGCCAGCCTTACACTTGACTCCAGTGGGAATGGCATACTGAGCCAGGCTTA
ACCTGTGACCAGCTCTGGATGGCCTCTGTCCAGGGACATCCGCACTGAGACATTGGACATCCGG
GGCCACACTGTACATTTGTCTGTCTTTCTGTGTGGCTTCTAAGGGCAGCAGCTGCAGCTGTTTA
GAAAAGCTCTTGGAGATCATGAACTTAAAAGAGAATTGCTTTCAGTGAAATCTTGACCAAAGTC
AGAGTAGACCTTGACGGTTCTGACAGCAGGGAGGTTTTCTTACCGGAGGCTTCCCTCCTTTCCT
ATCCCTGTGTCTGTGCTGTGGGAAGGGGGGCTGGGATGAGCAAGCTTCCGTCTCTGGGAATGTG
CAAAGTCAAAGACATGCGTCATGTGGTTCATCTGGTGCGTCCTATACCCTGGCTCCGCCCCTCT
GGTGGATGAGTCTAAGCCGTGTGGTGAGGCCCACAGCCCATCTGCCCCACTGTGACCTGAGTGG
GGAAGAAGTCTAAGCCCACACCACACCTGAGCGTGCACACGTGTGTCAGACTGTGTAGCCTCCT
CCAGGAAGCATAAGTGAGCAGGAATGGTAGCTAGCTCATGGCTGCACTCACGAGGGAGAGGCAG
AGGCAGGTGGGTCTCTGAGTTCAAGGCCACAAGCCCAGCCTGGTCTTCACTGTTCCTGGACAGC
CAGGGTTAACAGGGGTATAAATGATATAACTGATGTTGGA

hide sequence

RefSeq Acc Id:

NM_031352 ⟹ NP_112642

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	84,880,093 - 84,895,122 (+)	NCBI
mRatBN7.2	14	80,666,124 - 80,681,155 (+)	NCBI
Rnor_6.0	14	86,029,335 - 86,044,364 (+)	NCBI
Rnor_5.0	14	86,721,144 - 86,736,173 (+)	NCBI
RGSC_v3.4	14	86,450,448 - 86,481,863 (+)	RGD
Celera	14	79,551,079 - 79,566,108 (+)	NCBI

Sequence:

show sequence

TTCCGTCCGTCACTGGAGGCCGGCAGAAAGCTGAGGCTGCATCATTGCTGAGACCGTGGGGCGT
GACATGGCGGTGAACCTGAGCCGGAACGGGCCGGCGCTGCAGGAGGCCTATGTGCGGGTGGTCA
CCGAGAAATCCCCGACCGACTGGGCTCTTTTTACCTATGAAGGCAACAGCAATGACATCCGTGT
GGCTGGCACAGGGGAGGGAGGCCTGGAGGAGCTGGTGGAGGAGCTCAACAGCGGGAAGGTGATG
TACGCCTTCTGCAGGGTGAAGGACCCCAACTCTGGCCTGCCCAAGTTTGTCCTCATCAACTGGA
CAGGCGAGGGTGTGAATGATGTGCGAAAAGGAGCATGTGCCAACCACGTCAGCACCATGGCCAA
CTTCCTAAAGGGTGCCCATGTGACCATCAACGCACGGGCTGAGGAAGATGTGGAGCCTGAGTGC
ATCATGGAGAAGGTTGCCAAGGCTTCTGGGGCTAATTACAGCTTCCATAAGGAAAGCAGCTGCT
TCCAGGATGTGGGGCCTCAGGCCCCAGTGGGCTCTGTGTACCAGAAGACCAATGCCGTGTCTGA
GATCAAGAGAGTTGGCAAGGATAACTTCTGGGCCAAAGCTGAGAAGGAGGAGGAGAACCGCCGC
CTGGAGGAGAAGCGGCGGGCTGAAGAGGAGAAGCAGCGGCTGGAGGAGGAGCGGCGGGAGCGGG
AGCTGCAGGAGGCTGCCCGACGGGAACAACGCTACCAGGAACAGCACAGATCAGCTGGACCCCC
AAGCAGGACAGGTGAACTGGAGCAAGAGGTGGTTTCAAGGAGCAGACAGGAATGGGAGTCTGCT
GGGCAGCAGGCCCCACACCCACGGGAGATTTTCAAGCAGAAGGAAAGGGCTATGTCCACCACCT
CTGTCTCCAGCTCTCAGCCAGGCAAGCTGAGGAGCCCCTTCCTGCAGAAGCAGTTCACTCAACC
AGAAGCTTCCTATGGCCGAGAGCCCACTTCTCCTGTGTCACGGCCTGCAGCAGGTGTCTGCGAG
GAGCTGGCACCCAGCACTCCGCCCTCAGCCCAGACAGACGATGAACCTACATATGAAGTGCCCT
CCGAGCAGGAGACCCTGTACGAGGAACCACCACCGGTCCAGCAGCCAGGGGCTGGCTCCGGACA
CATTGACAACTACATGCAGAGCCAGGACCTCAGTGGGCAAGGACTGTGCGCTCGGGCCTTGTAC
GACTACCAGGCAGCTGACGACACGGAGATCTCCTTTGACCCTGAGAACCTAATCACAGGCATCG
AGGTGATTGACGAAGGCTGGTGGCGTGGCTATGGGCCTGACGGCCACTTTGGCATGTTTCCTGC
CAACTATGTGGAGCTCATAGAGTGAGCGAGGTCTGTTGTCCTTCTCTACCACAAGTGGCTTCCT
TGTTGCCTAAGAGTTAATGTTCGGCACTGTTCCAGAAATGGGACTTGAGTGAGGACAAGGCTTC
CTCTGCCCTGAGTGCTCCTGTTACCCCAGATATAGCAGCTCCCACTGCTCCCCCAAATGCTTAC
CGCAGCCTCTAGGCCCTTCTGCCAGCCTTACACTTGACTCCAGTGGGAATGGCATACTGAGCCA
GGCTTAACCTGTGACCAGCTCTGGATGGCCTCTGTCCAGGGACATCCGCACTGAGACATTGGAC
ATCCGGGGCCACACTGTACATTTGTCTGTCTTTCTGTGTGGCTTCTAAGGGCAGCAGCTGCAGC
TGTTTAGAAAAGCTCTTGGAGATCATGAACTTAAAAGAGAATTGCTTTCAGTGAAATCTTGACC
AAAGTCAGAGTAGACCTTGACGGTTCTGACAGCAGGGAGGTTTTCTTACCGGAGGCTTCCCTCC
TTTCCTATCCCTGTGTCTGTGCTGTGGGAAGGGGGGCTGGGATGAGCAAGCTTCCGTCTCTGGG
AATGTGCAAAGTCAAAGACATGCGTCATGTGGTTCATCTGGTGCGTCCTATACCCTGGCTCCGC
CCCTCTGGTGGATGAGTCTAAGCCGTGTGGTGAGGCCCACAGCCCATCTGCCCCACTGTGACCT
GAGTGGGGAAGAAGTCTAAGCCCACACCACACCTGAGCGTGCACACGTGTGTCAGACTGTGTAG
CCTCCTCCAGGAAGCATAAGTGAGCAGGAATGGTAGCTAGCTCATGGCTGCACTCACGAGGGAG
AGGCAGAGGCAGGTGGGTCTCTGAGTTCAAGGCCACAAGCCCAGCCTGGTCTTCACTGTTCCTG
GACAGCCAGGGTTAACAGGGGTATAAATGATATAACTGATGTTGGA

hide sequence

RefSeq Acc Id:

XM_039092499 ⟹ XP_038948427

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	84,880,085 - 84,892,065 (+)	NCBI
mRatBN7.2	14	80,666,115 - 80,678,024 (+)	NCBI

RefSeq Acc Id:

XM_039092500 ⟹ XP_038948428

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	84,880,085 - 84,892,065 (+)	NCBI
mRatBN7.2	14	80,666,115 - 80,678,024 (+)	NCBI

RefSeq Acc Id:

XM_039092501 ⟹ XP_038948429

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	84,880,085 - 84,892,065 (+)	NCBI
mRatBN7.2	14	80,666,115 - 80,678,024 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001264140	(Get FASTA)	NCBI Sequence Viewer
	NP_001264141	(Get FASTA)	NCBI Sequence Viewer
	NP_001264142	(Get FASTA)	NCBI Sequence Viewer
	NP_112642	(Get FASTA)	NCBI Sequence Viewer
	XP_038948427	(Get FASTA)	NCBI Sequence Viewer
	XP_038948428	(Get FASTA)	NCBI Sequence Viewer
	XP_038948429	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH72483	(Get FASTA)	NCBI Sequence Viewer
	BAA90819	(Get FASTA)	NCBI Sequence Viewer
	BAA90866	(Get FASTA)	NCBI Sequence Viewer
	BAA90867	(Get FASTA)	NCBI Sequence Viewer
	BAA92708	(Get FASTA)	NCBI Sequence Viewer
	BAA92709	(Get FASTA)	NCBI Sequence Viewer
	EDM00306	(Get FASTA)	NCBI Sequence Viewer
	EDM00307	(Get FASTA)	NCBI Sequence Viewer
	EDM00308	(Get FASTA)	NCBI Sequence Viewer
	EDM00309	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017375.7
GenBank Protein	Q9JHL4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_112642 ⟸ NM_031352
- Peptide Label:	isoform 2
- UniProtKB:	A6IKP2 (UniProtKB/TrEMBL), A6IKP5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVNLSRNGPALQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMY AFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECI MEKVAKASGANYSFHKESSCFQDVGPQAPVGSVYQKTNAVSEIKRVGKDNFWAKAEKEEENRRL EEKRRAEEEKQRLEEERRERELQEAARREQRYQEQHRSAGPPSRTGELEQEVVSRSRQEWESAG QQAPHPREIFKQKERAMSTTSVSSSQPGKLRSPFLQKQFTQPEASYGREPTSPVSRPAAGVCEE LAPSTPPSAQTDDEPTYEVPSEQETLYEEPPPVQQPGAGSGHIDNYMQSQDLSGQGLCARALYD YQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE hide sequence

RefSeq Acc Id:	NP_001264140 ⟸ NM_001277211
- Peptide Label:	isoform 1
- UniProtKB:	Q9JM67 (UniProtKB/Swiss-Prot), Q9JM66 (UniProtKB/Swiss-Prot), Q9JM74 (UniProtKB/Swiss-Prot), Q9JHL4 (UniProtKB/Swiss-Prot), A6IKP5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVNLSRNGPALQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMY AFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECI MEKVAKASGANYSFHKESSCFQDVGPQAPVGSVYQKTNAVSEIKRVGKDNFWAKAEKEEENRRL EEKRRAEEEKQRLEEERRERELQEAARREQRYQEQHRSAGPPSPSSRTGELEQEVVSRSRQEWE SAGQQAPHPREIFKQKERAMSTTSVSSSQPGKLRSPFLQKQFTQPEASYGREPTSPVSRPAAGV CEELAPSTPPSAQTDDEPTYEVPSEQETLYEEPPPVQQPGAGSGHIDNYMQSQDLSGQGLCARA LYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE hide sequence

RefSeq Acc Id:	NP_001264141 ⟸ NM_001277212
- Peptide Label:	isoform 3
- UniProtKB:	A6IKP5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVNLSRNGPALQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMY AFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECI MEKVAKASGANYSFHKESSCFQDVGPQAPVGSVYQKTNAVSEIKRVGKDNFWAKAEKEEENRRL EEKRRAEEEKQRLEEERRERELQEAARREQRYQEQHRSAGPPRTGELEQEVVSRSRQEWESAGQ QAPHPREIFKQKERAMSTTSVSSSQPGKLRSPFLQKQFTQPEASYGREPTSPVSRPAAGVCEEL APSTPPSAQTDDEPTYEVPSEQETLYEEPPPVQQPGAGSGHIDNYMQSQDLSGQGLCARALYDY QAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE hide sequence

RefSeq Acc Id:	NP_001264142 ⟸ NM_001277213
- Peptide Label:	isoform 4
- UniProtKB:	A6IKP5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVNLSRNGPALQEAYVRVVTEKSPTDWALFTYEGNSNDIRVAGTGEGGLEELVEELNSGKVMY AFCRVKDPNSGLPKFVLINWTGEGVNDVRKGACANHVSTMANFLKGAHVTINARAEEDVEPECI MEKVAKASGANYSFHKESSCFQDVGPQAPVGSVYQKTNAVSEIKRVGKDNFWAKAEKEEENRRL EEKRRAEEEKQRLEEERRERELQEAARREQRYQEQHRSAGPPRTGELEQEVVSRSRQEWSAGQQ APHPREIFKQKERAMSTTSVSSSQPGKLRSPFLQKQFTQPEASYGREPTSPVSRPAAGVCEELA PSTPPSAQTDDEPTYEVPSEQETLYEEPPPVQQPGAGSGHIDNYMQSQDLSGQGLCARALYDYQ AADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVELIE hide sequence

Ensembl Acc Id:

ENSRNOP00000017375 ⟸ ENSRNOT00000017375

RefSeq Acc Id:	XP_038948427 ⟸ XM_039092499
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038948428 ⟸ XM_039092500
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038948429 ⟸ XM_039092501
- Peptide Label:	isoform X3

Protein Domains

ADF-H SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9JHL4-F1-model_v2	AlphaFold	Q9JHL4	1-436	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699461

Promoter ID:

EPDNEW_R9985

Type:

initiation region

Name:

Dbnl_1

Description:

drebrin-like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	86,029,375 - 86,029,435	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:70941	AgrOrtholog
BioCyc Gene	G2FUF-15127	BioCyc
Ensembl Genes	ENSRNOG00000012378	Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000017375.8	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.20.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7104722	IMAGE-MGC_LOAD
InterPro	ADF-H	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ADF-H/Gelsolin-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Drebrin-like_SH3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SH3-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SH3_domain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:83527	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:91641	IMAGE-MGC_LOAD
NCBI Gene	83527	ENTREZGENE
PANTHER	CORTACTIN AND DREBRIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DREBRIN-LIKE PROTEIN	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam	Cofilin_ADF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SH3_9	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Dbnl	PhenoGen
PROSITE	ADF_H	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SH3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000012378	RatGTEx
SMART	ADF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SH3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Actin depolymerizing proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SH3-domain	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt	A6IKP2	ENTREZGENE, UniProtKB/TrEMBL
	A6IKP3_RAT	UniProtKB/TrEMBL
	A6IKP4_RAT	UniProtKB/TrEMBL
	A6IKP5	ENTREZGENE, UniProtKB/TrEMBL
	DBNL_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q9JM66	ENTREZGENE
	Q9JM67	ENTREZGENE
	Q9JM74	ENTREZGENE
UniProt Secondary	Q9JM66	UniProtKB/Swiss-Prot
	Q9JM67	UniProtKB/Swiss-Prot
	Q9JM74	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-07-09	Dbnl	drebrin-like			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a drebrin homology sequence and a cortactin homology sequence (SH3 domain)	70709

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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