Dbnl (drebrin-like) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dbnl (drebrin-like) Rattus norvegicus
Analyze
Symbol: Dbnl
Name: drebrin-like
RGD ID: 70941
Description: A structural constituent of postsynaptic actin cytoskeleton. Involved in postsynaptic actin cytoskeleton organization. Located in dendrite. Is active in glutamatergic synapse; postsynapse; and presynapse. Orthologous to human DBNL (drebrin like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: abp1; actin-binding protein 1; drebrin-like protein; SH3 domain-containing protein 7; Sh3p7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,880,085 - 84,895,122 (+)NCBIGRCr8
mRatBN7.21480,666,115 - 80,681,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,666,124 - 80,681,155 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,068,401 - 85,083,685 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,308,505 - 86,323,788 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,757,826 - 82,773,110 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,029,335 - 86,044,364 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,029,335 - 86,044,364 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,721,144 - 86,736,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,450,448 - 86,481,863 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,469,592 - 86,484,067 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation. Haeckel A, etal., J Neurosci. 2008 Oct 1;28(40):10031-44. doi: 10.1523/JNEUROSCI.0336-08.2008.
3. Gene Data Set MGD Curation, June 12, 2002
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family. Qualmann B, etal., J Neurosci. 2004 Mar 10;24(10):2481-95.
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Molecular cloning and dendritic localization of rat SH3P7. Yamazaki H, etal., Eur J Neurosci 2001 Sep;14(6):998-1008.
Additional References at PubMed
PMID:9630982   PMID:10637315   PMID:12913069   PMID:15489334   PMID:16641100   PMID:19056867   PMID:22303001   PMID:24802081   PMID:25468996   PMID:28235806   PMID:30053369  


Genomics

Comparative Map Data
Dbnl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,880,085 - 84,895,122 (+)NCBIGRCr8
mRatBN7.21480,666,115 - 80,681,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,666,124 - 80,681,155 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1485,068,401 - 85,083,685 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,308,505 - 86,323,788 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,757,826 - 82,773,110 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,029,335 - 86,044,364 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1486,029,335 - 86,044,364 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,721,144 - 86,736,173 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,450,448 - 86,481,863 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,469,592 - 86,484,067 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBICelera
Cytogenetic Map14q21NCBI
DBNL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,044,702 - 44,069,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,044,640 - 44,069,456 (+)EnsemblGRCh38hg38GRCh38
GRCh37744,084,301 - 44,109,055 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,050,830 - 44,067,840 (+)NCBINCBI36Build 36hg18NCBI36
Celera744,182,185 - 44,199,260 (+)NCBICelera
Cytogenetic Map7p13NCBI
HuRef743,969,523 - 43,986,598 (+)NCBIHuRef
CHM1_1744,088,113 - 44,105,189 (+)NCBICHM1_1
T2T-CHM13v2.0744,203,197 - 44,227,954 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,123,733 - 44,140,805 (+)NCBI
Dbnl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,730,233 - 5,750,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,738,488 - 5,750,962 (+)EnsemblGRCm39 Ensembl
GRCm38115,788,483 - 5,800,980 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,788,488 - 5,800,962 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,688,486 - 5,700,983 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,688,533 - 5,700,965 (+)NCBIMGSCv36mm8
Celera116,278,834 - 6,291,141 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.87NCBI
Dbnl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,912,827 - 7,924,787 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554567,912,827 - 7,924,373 (-)NCBIChiLan1.0ChiLan1.0
DBNL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2648,950,223 - 48,972,891 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,276,140 - 97,297,574 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,753,062 - 44,775,717 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,824,537 - 44,842,059 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,824,608 - 44,845,891 (+)Ensemblpanpan1.1panPan2
DBNL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha161,996,510 - 2,007,305 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,854,694 - 14,865,499 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,854,694 - 14,877,271 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,485,876 - 14,496,666 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,466,360 - 14,477,156 (-)NCBIUU_Cfam_GSD_1.0
Dbnl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,795,888 - 99,809,337 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,007,672 - 19,020,361 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,007,630 - 19,021,068 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DBNL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,713,340 - 48,725,697 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,713,335 - 48,725,692 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21853,426,424 - 53,438,753 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DBNL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,610,196 - 14,627,363 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,608,571 - 14,627,321 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660627,886,798 - 7,904,467 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dbnl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,950,556 - 7,960,568 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247407,950,552 - 7,960,592 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dbnl
67 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:293
Count of miRNA genes:183
Interacting mature miRNAs:201
Transcripts:ENSRNOT00000017375
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143766971982669719Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)146875779683368335Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143032009280829842Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147341532392554092Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143766971982669719Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147341532392554092Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532392554092Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143766971982669719Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143905723783368335Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143766971982669719Rat

Markers in Region
D14Mgh1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,684,833 - 80,684,938 (+)MAPPERmRatBN7.2
Rnor_6.01486,048,043 - 86,048,147NCBIRnor6.0
Rnor_5.01486,739,852 - 86,739,956UniSTSRnor5.0
RGSC_v3.41486,469,093 - 86,469,197UniSTSRGSC3.4
Celera1479,569,638 - 79,569,742UniSTS
RH 3.4 Map14571.5UniSTS
RH 3.4 Map14571.5RGD
RH 2.0 Map14702.9RGD
SHRSP x BN Map1444.8999RGD
Cytogenetic Map14q21UniSTS
Cytogenetic Map14q21-q22UniSTS
D14Rat19  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,684,320 - 80,684,482 (+)MAPPERmRatBN7.2
Rnor_6.01486,047,530 - 86,047,691NCBIRnor6.0
Rnor_5.01486,739,339 - 86,739,500UniSTSRnor5.0
RGSC_v3.41486,468,542 - 86,468,937RGDRGSC3.4
RGSC_v3.41486,468,580 - 86,468,741UniSTSRGSC3.4
RGSC_v3.11486,487,725 - 86,487,886RGD
RH 3.4 Map14571.5RGD
RH 3.4 Map14571.5UniSTS
RH 2.0 Map14702.7RGD
SHRSP x BN Map1445.38RGD
Cytogenetic Map14q21-q22UniSTS
Cytogenetic Map14q21UniSTS
AW532217  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,690,859 - 80,690,958 (+)MAPPERmRatBN7.2
Rnor_6.01486,054,068 - 86,054,166NCBIRnor6.0
Rnor_5.01486,745,877 - 86,745,975UniSTSRnor5.0
RGSC_v3.41486,475,118 - 86,475,216UniSTSRGSC3.4
Celera1479,575,631 - 79,575,729UniSTS
RH 3.4 Map14572.7UniSTS
Cytogenetic Map14q21UniSTS
AW527377  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,682,949 - 80,683,113 (+)MAPPERmRatBN7.2
Rnor_6.01486,046,159 - 86,046,322NCBIRnor6.0
Rnor_5.01486,737,968 - 86,738,131UniSTSRnor5.0
RGSC_v3.41486,467,209 - 86,467,372UniSTSRGSC3.4
Celera1479,567,903 - 79,568,066UniSTS
RH 3.4 Map14571.5UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map14q21-q22UniSTS
AI713198  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,680,929 - 80,681,084 (+)MAPPERmRatBN7.2
Rnor_6.01486,044,139 - 86,044,293NCBIRnor6.0
Rnor_5.01486,735,948 - 86,736,102UniSTSRnor5.0
RGSC_v3.41486,465,189 - 86,465,343UniSTSRGSC3.4
Celera1479,565,883 - 79,566,037UniSTS
RH 3.4 Map14573.2UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001277211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001277212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001277213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB009346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB038364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB038365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC128636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC072483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000017375   ⟹   ENSRNOP00000017375
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1480,666,124 - 80,681,155 (+)Ensembl
Rnor_6.0 Ensembl1486,029,335 - 86,044,364 (+)Ensembl
RefSeq Acc Id: NM_001277211   ⟹   NP_001264140
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,093 - 84,895,122 (+)NCBI
mRatBN7.21480,666,124 - 80,681,155 (+)NCBI
Rnor_6.01486,029,335 - 86,044,364 (+)NCBI
Rnor_5.01486,721,144 - 86,736,173 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001277212   ⟹   NP_001264141
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,093 - 84,895,122 (+)NCBI
mRatBN7.21480,666,124 - 80,681,155 (+)NCBI
Rnor_6.01486,029,335 - 86,044,364 (+)NCBI
Rnor_5.01486,721,144 - 86,736,173 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001277213   ⟹   NP_001264142
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,093 - 84,895,122 (+)NCBI
mRatBN7.21480,666,124 - 80,681,155 (+)NCBI
Rnor_6.01486,029,335 - 86,044,364 (+)NCBI
Rnor_5.01486,721,144 - 86,736,173 (+)NCBI
Celera1479,551,079 - 79,566,108 (+)NCBI
Sequence:
RefSeq Acc Id: NM_031352   ⟹   NP_112642
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,093 - 84,895,122 (+)NCBI
mRatBN7.21480,666,124 - 80,681,155 (+)NCBI
Rnor_6.01486,029,335 - 86,044,364 (+)NCBI
Rnor_5.01486,721,144 - 86,736,173 (+)NCBI
RGSC_v3.41486,450,448 - 86,481,863 (+)RGD
Celera1479,551,079 - 79,566,108 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092499   ⟹   XP_038948427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,085 - 84,892,065 (+)NCBI
mRatBN7.21480,666,115 - 80,678,024 (+)NCBI
RefSeq Acc Id: XM_039092500   ⟹   XP_038948428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,085 - 84,892,065 (+)NCBI
mRatBN7.21480,666,115 - 80,678,024 (+)NCBI
RefSeq Acc Id: XM_039092501   ⟹   XP_038948429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,880,085 - 84,892,065 (+)NCBI
mRatBN7.21480,666,115 - 80,678,024 (+)NCBI
RefSeq Acc Id: NP_112642   ⟸   NM_031352
- Peptide Label: isoform 2
- UniProtKB: A6IKP2 (UniProtKB/TrEMBL),   A6IKP5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264140   ⟸   NM_001277211
- Peptide Label: isoform 1
- UniProtKB: Q9JM67 (UniProtKB/Swiss-Prot),   Q9JM66 (UniProtKB/Swiss-Prot),   Q9JM74 (UniProtKB/Swiss-Prot),   Q9JHL4 (UniProtKB/Swiss-Prot),   A6IKP5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264141   ⟸   NM_001277212
- Peptide Label: isoform 3
- UniProtKB: A6IKP5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264142   ⟸   NM_001277213
- Peptide Label: isoform 4
- UniProtKB: A6IKP5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017375   ⟸   ENSRNOT00000017375
RefSeq Acc Id: XP_038948427   ⟸   XM_039092499
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038948428   ⟸   XM_039092500
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038948429   ⟸   XM_039092501
- Peptide Label: isoform X3
Protein Domains
ADF-H   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JHL4-F1-model_v2 AlphaFold Q9JHL4 1-436 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699461
Promoter ID:EPDNEW_R9985
Type:initiation region
Name:Dbnl_1
Description:drebrin-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,029,375 - 86,029,435EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70941 AgrOrtholog
BioCyc Gene G2FUF-15127 BioCyc
Ensembl Genes ENSRNOG00000012378 Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017375.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7104722 IMAGE-MGC_LOAD
InterPro ADF-H UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADF-H/Gelsolin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Drebrin-like_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83527 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91641 IMAGE-MGC_LOAD
NCBI Gene 83527 ENTREZGENE
PANTHER CORTACTIN AND DREBRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DREBRIN-LIKE PROTEIN UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam Cofilin_ADF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dbnl PhenoGen
PROSITE ADF_H UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012378 RatGTEx
SMART ADF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-domain UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6IKP2 ENTREZGENE, UniProtKB/TrEMBL
  A6IKP3_RAT UniProtKB/TrEMBL
  A6IKP4_RAT UniProtKB/TrEMBL
  A6IKP5 ENTREZGENE, UniProtKB/TrEMBL
  DBNL_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JM66 ENTREZGENE
  Q9JM67 ENTREZGENE
  Q9JM74 ENTREZGENE
UniProt Secondary Q9JM66 UniProtKB/Swiss-Prot
  Q9JM67 UniProtKB/Swiss-Prot
  Q9JM74 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Dbnl  drebrin-like      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains a drebrin homology sequence and a cortactin homology sequence (SH3 domain) 70709