Advanced Search (OLGA)

Gene: Mapk8ip1 (mitogen-activated protein kinase 8 interacting protein 1) Rattus norvegicus

Analyze

Symbol:

Mapk8ip1

Name:

mitogen-activated protein kinase 8 interacting protein 1

RGD ID:

70937

Description:

Enables MAP-kinase scaffold activity; identical protein binding activity; and protein kinase binding activity. Involved in negative regulation of JUN kinase activity and negative regulation of apoptotic process. Located in axonal growth cone; dendritic growth cone; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

C-jun-amino-terminal kinase-interacting protein 1; IB-1; islet-brain-1; Jip-1; JIP-1-related protein; JIP1; JNK MAP kinase scaffold protein 1; JNK-interacting protein 1; JRP; Mapk8ip; mitogen activated protein kinase 8 interacting protein; mitogen-activated protein kinase 8-interacting protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	98,810,540 - 98,829,302 (-)	NCBI		GRCr8
GRCr8 Ensembl	3	98,810,541 - 98,828,368 (-)	Ensembl		GRCr8 Ensembl
mRatBN7.2	3	78,355,051 - 78,372,946 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	78,355,048 - 78,372,884 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	81,830,830 - 81,839,989 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	90,429,871 - 90,439,030 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	88,280,966 - 88,290,137 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	81,295,023 - 81,304,181 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	81,295,024 - 81,304,181 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	87,998,491 - 88,016,191 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	76,781,504 - 76,790,661 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	77,557,046 - 77,566,196 (-)	NCBI		Celera
RGSC_v3.1	3	76,677,932 - 76,687,089 (-)	NCBI
Cytogenetic Map	3	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital disorder of glycosylation type IIc (ISO)

infantile Refsum disease (ISO)

intellectual disability (ISO)

maturity-onset diabetes of the young type 1 (ISO)

type 2 diabetes mellitus (ISO)

Zellweger syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methoxyethanol (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

4-vinylcyclohexene dioxide (ISO)

acetamide (EXP)

acetylleucyl-leucyl-norleucinal (EXP,ISO)

aflatoxin B1 (ISO)

amitrole (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

C60 fullerene (EXP)

cadmium dichloride (ISO)

cannabidiol (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

clozapine (ISO)

DDE (ISO)

diarsenic trioxide (ISO)

diazinon (EXP)

dibutyl phthalate (EXP)

dieldrin (EXP)

diuron (EXP)

doxorubicin (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

furan (EXP)

gentamycin (EXP)

L-methionine (ISO)

lactacystin (EXP,ISO)

Licochalcone B (ISO)

methoxychlor (EXP,ISO)

Mitotane (EXP)

monosodium L-glutamate (EXP)

N-methyl-4-phenylpyridinium (ISO)

nickel dichloride (EXP)

perfluorooctane-1-sulfonic acid (EXP)

phencyclidine (ISO)

phenylephrine (EXP)

phorbol 13-acetate 12-myristate (EXP)

pirinixic acid (ISO)

resveratrol (ISO)

rotenone (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

T-2 toxin (ISO)

tetrachloromethane (EXP,ISO)

titanium dioxide (ISO)

trichloroethene (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

JNK cascade (IBA)

JUN phosphorylation (ISO)

negative regulation of apoptotic process (IDA)

negative regulation of intrinsic apoptotic signaling pathway (IEA,ISO)

negative regulation of JNK cascade (IMP)

negative regulation of JUN kinase activity (IMP)

positive regulation of JNK cascade (IEA,ISO,ISS)

regulation of CD8-positive, alpha-beta T cell proliferation (IEA,ISO,ISS)

regulation of DNA-templated transcription (IEA,ISO)

regulation of JNK cascade (IEA,ISO,ISS)

regulation of signal transduction (IEA)

signal transduction (IEA,ISO)

vesicle-mediated transport (IEA,ISO)

Cellular Component

axon (IEA,ISO)

axonal growth cone (IDA)

cytoplasm (IBA,IDA,IEA,ISO)

cytosol (IEA,ISO)

dendrite (IEA,ISO)

dendritic growth cone (IDA)

dentate gyrus mossy fiber (IEA,ISO)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

membrane (IEA,ISO)

mitochondrial membrane (IEA)

mitochondrion (IEA)

neuron projection (IEA,ISO)

neuronal cell body (IEA,ISO)

nucleus (IEA)

perinuclear region of cytoplasm (IDA,IEA)

plasma membrane (IEA,ISO)

synapse (IEA,ISO)

Molecular Function

identical protein binding (IPI)

JUN kinase binding (IBA,IPI)

kinesin binding (IEA,ISO,ISS)

MAP-kinase scaffold activity (IBA,IEA,IMP,ISO)

mitogen-activated protein kinase kinase binding (IPI)

mitogen-activated protein kinase kinase kinase binding (IPI)

protein binding (IPI,ISO)

protein kinase binding (IEA,ISO,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

c-Jun N-terminal kinases MAPK signaling pathway (IDA,ISO)

mitogen activated protein kinase signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	IB1, a JIP-1-related nuclear protein present in insulin-secreting cells.	Bonny C, etal., J Biol Chem 1998 Jan 23;273(4):1843-6.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	c-Jun N-terminal kinase (JNK) and JNK interacting protein response in rat brain after transient middle cerebral artery occlusion.	Hayashi T, etal., Neurosci Lett. 2000 Apr 28;284(3):195-9.
5.	Akt1 regulates a JNK scaffold during excitotoxic apoptosis.	Kim AH, etal., Neuron 2002 Aug 15;35(4):697-709.
6.	Molecular cloning of multiple splicing variants of JIP-1 preferentially expressed in brain.	Kim IJ, etal., J Neurochem 1999 Apr;72(4):1335-43.
7.	A unique set of SH3-SH3 interactions controls IB1 homodimerization.	Kristensen O, etal., EMBO J. 2006 Feb 22;25(4):785-97. Epub 2006 Feb 2.
8.	Activated mitogen-activated protein kinase kinase 7 redistributes to the cytosol and binds to Jun N-terminal kinase-interacting protein 1 involving oxidative stress during early reperfusion in rat hippocampal CA1 region.	Li CH, etal., J Neurochem. 2005 Apr;93(2):290-8.
9.	Gene Data Set	MGD Curation, June 12, 2002
10.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
11.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
12.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
13.	Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain.	Pellet JB, etal., Eur J Neurosci. 2000 Feb;12(2):621-32.
14.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
15.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
17.	Connexin26 is regulated in rat urothelium by the scaffold protein IB1/JIP-1.	Tawadros T, etal., Cell Commun Adhes 2001;8(4-6):303-6.
18.	Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein.	Wilhelm M, etal., J Biol Chem. 2012 Jan 13;287(3):2247-56. doi: 10.1074/jbc.M111.269431. Epub 2011 Nov 28.
19.	Regulation of stress-associated scaffold proteins JIP1 and JIP3 on the c-Jun NH2-terminal kinase in ischemia-reperfusion.	Xu B, etal., Can J Physiol Pharmacol. 2010 Nov;88(11):1084-92. doi: 10.1139/y10-088.
20.	Crosstalk between PSD-95 and JIP1-mediated signaling modules: the mechanism of MLK3 activation in cerebral ischemia.	Zhang QX, etal., Biochemistry. 2007 Apr 3;46(13):4006-16. Epub 2007 Mar 10.
21.	Regulatory mechanisms of mitogen-activated kinase signaling.	Zhang Y and Dong C, Cell Mol Life Sci. 2007 Nov;64(21):2771-89.

Additional References at PubMed

PMID:9235893	PMID:10574993	PMID:11238452	PMID:11562351	PMID:15345675	PMID:16301330	PMID:20816823	PMID:23825109	PMID:23963642	PMID:24478353	PMID:26665154	PMID:28886967
PMID:36902422

Genomics

Comparative Map Data

Mapk8ip1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	98,810,540 - 98,829,302 (-)	NCBI		GRCr8
GRCr8 Ensembl	3	98,810,541 - 98,828,368 (-)	Ensembl		GRCr8 Ensembl
mRatBN7.2	3	78,355,051 - 78,372,946 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	78,355,048 - 78,372,884 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	81,830,830 - 81,839,989 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	90,429,871 - 90,439,030 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	88,280,966 - 88,290,137 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	81,295,023 - 81,304,181 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	81,295,024 - 81,304,181 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	87,998,491 - 88,016,191 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	76,781,504 - 76,790,661 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	3	77,557,046 - 77,566,196 (-)	NCBI		Celera
RGSC_v3.1	3	76,677,932 - 76,687,089 (-)	NCBI
Cytogenetic Map	3	q24	NCBI

MAPK8IP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	45,885,651 - 45,906,465 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	45,885,651 - 45,906,465 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	45,907,202 - 45,928,016 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	45,863,778 - 45,884,592 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	45,863,777 - 45,884,591	NCBI
Celera	11	46,054,811 - 46,075,621 (+)	NCBI		Celera
Cytogenetic Map	11	p11.2	NCBI
HuRef	11	45,613,904 - 45,634,868 (+)	NCBI		HuRef
CHM1_1	11	45,904,472 - 45,925,436 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	46,041,587 - 46,062,395 (+)	NCBI		T2T-CHM13v2.0

Mapk8ip1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	92,214,021 - 92,231,608 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	92,214,021 - 92,231,608 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	92,383,671 - 92,401,346 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	92,383,676 - 92,401,263 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	92,223,837 - 92,241,420 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	92,184,519 - 92,202,102 (-)	NCBI		MGSCv36	mm8
Celera	2	93,776,808 - 93,794,307 (-)	NCBI		Celera
Cytogenetic Map	2	E1	NCBI
cM Map	2	50.99	NCBI

Mapk8ip1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	2,061,851 - 2,082,514 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	2,064,010 - 2,081,681 (-)	NCBI	ChiLan1.0	ChiLan1.0

MAPK8IP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	48,094,027 - 48,114,916 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	48,100,901 - 48,121,788 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	45,839,754 - 45,860,615 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	46,332,121 - 46,352,750 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	46,332,159 - 46,352,010 (+)	Ensembl	panpan1.1		panPan2

MAPK8IP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	43,517,186 - 43,522,603 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	43,517,677 - 43,526,379 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	42,245,214 - 42,263,683 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	44,173,152 - 44,191,616 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	44,173,163 - 44,192,012 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	43,657,404 - 43,675,863 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	43,210,353 - 43,228,830 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	43,942,641 - 43,961,111 (-)	NCBI		UU_Cfam_GSD_1.0

Mapk8ip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	21,001,575 - 21,011,189 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936562	3,109,547 - 3,122,939 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936562	3,113,217 - 3,122,794 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAPK8IP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	16,564,257 - 16,584,768 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	16,562,687 - 16,584,763 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	17,929,057 - 17,949,520 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAPK8IP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	19,435,593 - 19,457,073 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	19,432,631 - 19,442,185 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	116,712,446 - 116,733,704 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mapk8ip1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	2,603,483 - 2,620,536 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	2,603,483 - 2,620,574 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mapk8ip1
37 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	433
Count of miRNA genes:	199
Interacting mature miRNAs:	251
Transcripts:	ENSRNOT00000009725, ENSRNOT00000074106
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300178	Hrtrt4	Heart rate QTL 4	3.74		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	51490129	111359995	Rat
61377	Edpm3	Estrogen-dependent pituitary mass QTL 3	7.05	0.038	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	73592611	110333156	Rat
1358293	Bw38	Body weight QTL 38	6	0.0000031	body mass (VT:0001259)	body weight (CMO:0000012)	3	74364268	119364268	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	96509147	141509147	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	73592512	136118980	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	51581665	184004958	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	67641776	167835660	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	58601291	153936591	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	49872657	138829559	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	73592512	136118980	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	85062224	136118980	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	85062224	136118980	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	81425008	141509147	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	70845569	136091483	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	93829559	138829559	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	79649560	177741895	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	96509147	141509147	Rat
738019	Anxrr10	Anxiety related response QTL 10	3.9		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	3	58925062	103925062	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	70311536	115311536	Rat
631200	Cm25	Cardiac mass QTL 25	4.8	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	3	81541464	126563126	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	90755164	141509147	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	36721849	110333156	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	1	141509147	Rat
1354597	Kidm13	Kidney mass QTL 13	2.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	3	42158111	124558371	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	98651826	167012663	Rat
1354604	Bw36	Body weight QTL 36	2.9		body mass (VT:0001259)	body weight (CMO:0000012)	3	42158111	124558371	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	5675975	141509147	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	67641995	130815812	Rat

Markers in Region

RH135410

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	78,355,089 - 78,355,301 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	81,295,062 - 81,295,273	NCBI	Rnor6.0
Rnor_5.0	3	87,998,530 - 87,998,741	UniSTS	Rnor5.0
RGSC_v3.4	3	76,781,543 - 76,781,754	UniSTS	RGSC3.4
Celera	3	77,557,085 - 77,557,296	UniSTS
RH 3.4 Map	3	707.2	UniSTS
Cytogenetic Map	3	q24	UniSTS

BE118974

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	78,360,791 - 78,360,986 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	81,300,764 - 81,300,958	NCBI	Rnor6.0
Rnor_5.0	3	88,004,232 - 88,004,426	UniSTS	Rnor5.0
RGSC_v3.4	3	76,787,245 - 76,787,439	UniSTS	RGSC3.4
Celera	3	77,562,787 - 77,562,981	UniSTS
RH 3.4 Map	3	708.4	UniSTS
Cytogenetic Map	3	q24	UniSTS

BF391846

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	78,362,388 - 78,362,579 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	81,302,361 - 81,302,551	NCBI	Rnor6.0
Rnor_5.0	3	88,005,829 - 88,006,019	UniSTS	Rnor5.0
RGSC_v3.4	3	76,788,842 - 76,789,032	UniSTS	RGSC3.4
Celera	3	77,564,377 - 77,564,567	UniSTS
Cytogenetic Map	3	q24	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
9	11	49	113	91	90	59	25	59	6	218	97	11	93	45	60	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001429682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429683	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001429684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_053777	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104100	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104101	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC129036	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF092450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF108959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF109772	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF109773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF109774	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ377223	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000079746 ⟹ ENSRNOP00000074684

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	98,810,541 - 98,819,697 (-)	Ensembl
mRatBN7.2 Ensembl	3	78,355,052 - 78,364,208 (-)	Ensembl
Rnor_6.0 Ensembl	3	81,295,024 - 81,304,181 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111802 ⟹ ENSRNOP00000089891

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	98,810,542 - 98,828,368 (-)	Ensembl
mRatBN7.2 Ensembl	3	78,355,053 - 78,372,884 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117436 ⟹ ENSRNOP00000090670

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	98,810,541 - 98,828,141 (-)	Ensembl
mRatBN7.2 Ensembl	3	78,355,048 - 78,372,884 (-)	Ensembl

RefSeq Acc Id:

NM_053777 ⟹ NP_446229

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	98,810,540 - 98,819,697 (-)	NCBI
mRatBN7.2	3	78,355,051 - 78,364,208 (-)	NCBI
Rnor_6.0	3	81,295,023 - 81,304,181 (-)	NCBI
Rnor_5.0	3	87,998,491 - 88,016,191 (-)	NCBI
RGSC_v3.4	3	76,781,504 - 76,790,661 (-)	RGD
Celera	3	77,557,046 - 77,566,196 (-)	RGD

Sequence:

show sequence

GGGCTGGGGCCTGGGTCGGCAGCTGCGGCCTCCTCTCTGGCCCATCTATTTTTAATGAGCTCCC
CGGGCTTCTGCAGCCGGCAGAATGCAGAAAGGCAGGCCCAGTCTGTGGAGGCCAGAAGTCCCAG
CCCTGCCTTGAGCTCTGGCCCCCCTACCCTTCTGGGCATGAAAGGGCAGCTCTGGAGCCCCGCA
GCCCCCTGGCCGGGCAGGGCTCTCCATGCAGCTGGTACTGAAGATGGATTCGAGCCCAGACAAT
GACAGCTGGTTGGAGGATCAGTGGGAACGCTGGCTCACCCATGATATCAGCCTGGAGGAGTTTG
AGGATGAAGACCTTTCGGAGATCACTGATGAGTGTGGCATCAGCCTGCAGTGCAAAGACACCTT
GTCTCTCCGGCCCCCGCGCGCCGGGCTACTGTCTGCGGGTAGCAGCGGTAGCGCGGGGAGCCGG
CTGCAGGCGGAGATGCTGCAGATGGACCTGATCGACGCGGCAAGTGACACTCCGGGCGCCGAGG
ACGACGAAGAGGACGACGACGAGCTCGCTGCCCAACGGCCAGGAGTGGGGCCTTCCAAAGCCGA
GTCTGGCCAGGAGCCGGCGTCTCGCAGCCAGGGTCAGGGCCAGGGCCCCGGCACAGGCAGCGGA
GACACCTACCGGCCCAAGAGGCCTACCACGCTCAACCTTTTCCCGCAGGTGCCGCGGTCTCAGG
ACACGCTGAATAATAACTCTTTAGGCAAAAAGCACAGTTGGCAGGACCGTGTGTCTCGATCATC
CTCCCCTCTGAAGACAGGGGAGCAGACGCCTCCACATGAACATATCTGCCTGAGTGATGAGCTG
CCGCCCCAGGGCAGTCCTGTTCCCACCCAGGATCGTGGCACTTCCACCGACAGCCCTTGTCGCC
GTACTGCAGCCACCCAGATGGCACCTCCAAGTGGTCCCCCTGCCACTGCACCTGGTGGCCGGGG
CCACTCCCATCGAGATCGAATCCACTATCAGGCAGATGTGCGGCTCGAGGCGACTGAGGAGATC
TACCTGACCCCAGTGCAGAGGCCCCCAGACCCTGCAGAACCCACCTCCACCTTCTTGCCACCCA
CTGAGAGCCGGATGTCTGTCAGCTCGGATCCTGACCCTGCCGCTTACTCTGTAACTGCAGGGCG
ACCGCACCCTTCCATCAGTGAAGAGGATGAGGGCTTCGACTGTCTGTCATCCCCAGAGCAAGCT
GAGCCACCAGGTGGAGGGTGGCGGGGAAGCCTCGGGGAGCCACCACCGCCTCCACGGGCCTCAC
TGAGCTCGGACACCAGCGCACTGTCCTACGACTCTGTCAAGTACACACTGGTGGTGGATGAGCA
TGCCCAGCTTGAGTTGGTGAGCCTGCGGCCATGTTTTGGAGATTACAGTGACGAAAGCGACTCT
GCCACTGTCTATGACAACTGTGCCTCTGCCTCCTCGCCCTACGAGTCAGCCATTGGTGAGGAAT
ATGAGGAGGCCCCTCAACCCCGGCCTCCCACCTGCCTGTCAGAGGACTCCACACCGGATGAGCC
TGACGTCCACTTCTCTAAGAAGTTTCTGAATGTCTTCATGAGTGGCCGCTCTCGTTCCTCCAGT
GCCGAGTCCTTTGGGCTGTTCTCCTGTGTCATCAATGGGGAGGAGCATGAGCAAACCCATCGGG
CTATATTCAGGTTTGTGCCTCGGCATGAAGATGAACTTGAGCTGGAAGTGGACGACCCTCTGCT
GGTGGAGCTGCAGGCAGAAGACTATTGGTATGAGGCCTATAACATGCGCACTGGAGCCCGTGGT
GTCTTTCCTGCCTACTATGCCATTGAGGTCACCAAGGAGCCTGAGCACATGGCAGCCCTTGCCA
AAAACAGCGACTGGATTGACCAGTTCCGGGTGAAGTTCCTGGGCTCTGTCCAGGTTCCTTATCA
CAAGGGCAATGATGTCCTCTGTGCTGCTATGCAAAAGATCGCCACCACCCGCCGGCTCACCGTG
CACTTTAACCCGCCCTCCAGCTGTGTCCTTGAAATCAGCGTTAGGGGTGTCAAGATAGGTGTCA
AAGCTGATGAAGCTCAGGAGGCCAAGGGAAATAAATGTAGCCACTTTTTCCAGCTAAAAAACAT
CTCTTTCTGTGGGTACCATCCAAAGAACAACAAGTACTTTGGGTTTATCACTAAGCACCCTGCT
GACCACCGGTTTGCCTGCCATGTCTTTGTGTCTGAAGATTCCACCAAAGCCCTGGCAGAGTCTG
TGGGGCGTGCATTTCAGCAGTTCTACAAGCAATTTGTGGAATATACCTGTCCTACAGAAGATAT
CTACTTGGAGTAGCAGCAACCCCCCTCTCTGCAGCCCCTCAGCCCCAGGCCAGTACTAGGACAG
CTGACTGCTGACAGGATGTTGTACTGCCACGAGAGAATGGGGGAGTGAGGGCTGTTGGGGTCGG
GGGGCAGGGGTTTGGGGAGAGGCAGATGCAGTTTATTGTAATATATGGGGTTAGATTAATCTAT
GGAGGACAGTACAGGCTCTCTCGGGGCTGGGGAAGGGCAGGGCTGGGGTGGGGGTCAGGCATCT
GGCCACAAAGGGATCCCCTAGGGACAGAGGCGCTGCACCATCCTGGGCCTTGTTTCATACTAGA
GGCCCTGGCTTTCTGGCTCTTGGGTCCTGCCTTGACAAAGCCCATGCCACCTGGAAGTGTCACC
TTCCCTTGTCCACCTCACCCAGAGCCCTGAGCTCATGCTGAGCCCAAGCACCTCCGAAGGACTT
TCCAGTAAGGAAATGGCAACATGTGACAGTGAGGACCCTGTTCTCATCTGTGGGGCCTCCGGCA
GCTCCGACCTCCAGCCTGGCCAGCACGCTGACCCTGGCAAGCTTGTGTGTTCAAAGAAGGAGAG
GGCCACAGCAAGCCCTGCCTGCCAGGGAAGGTTCCCTCTCAGCTGGCCCCAGCCAACTGGTCAC
TGTCTTGTCACCTGGCTACTACTATTAAAGTGCCATTTCTTGTCTGGAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039104100 ⟹ XP_038960028

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	98,810,540 - 98,829,302 (-)	NCBI
mRatBN7.2	3	78,355,051 - 78,372,901 (-)	NCBI

RefSeq Acc Id:

XM_039104101 ⟹ XP_038960029

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	98,810,540 - 98,824,635 (-)	NCBI
mRatBN7.2	3	78,355,051 - 78,364,457 (-)	NCBI

RefSeq Acc Id:

XM_039104102 ⟹ XP_038960030

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	98,810,540 - 98,829,302 (-)	NCBI
mRatBN7.2	3	78,355,051 - 78,372,946 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001416611	(Get FASTA)	NCBI Sequence Viewer
	NP_001416612	(Get FASTA)	NCBI Sequence Viewer
	NP_001416613	(Get FASTA)	NCBI Sequence Viewer
	NP_446229	(Get FASTA)	NCBI Sequence Viewer
	XP_038960028	(Get FASTA)	NCBI Sequence Viewer
	XP_038960029	(Get FASTA)	NCBI Sequence Viewer
	XP_038960030	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC62110	(Get FASTA)	NCBI Sequence Viewer
	AAD22543	(Get FASTA)	NCBI Sequence Viewer
	AAD38350	(Get FASTA)	NCBI Sequence Viewer
	AAD38351	(Get FASTA)	NCBI Sequence Viewer
	AAD38352	(Get FASTA)	NCBI Sequence Viewer
	ABD24062	(Get FASTA)	NCBI Sequence Viewer
	EDL79569	(Get FASTA)	NCBI Sequence Viewer
	EDL79570	(Get FASTA)	NCBI Sequence Viewer
	EDL79571	(Get FASTA)	NCBI Sequence Viewer
	EDL79572	(Get FASTA)	NCBI Sequence Viewer
	EDL79573	(Get FASTA)	NCBI Sequence Viewer
	EDL79574	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074684
	ENSRNOP00000074684.1
	ENSRNOP00000089891
	ENSRNOP00000090670.1
GenBank Protein	Q9R237	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_446229 ⟸ NM_053777

- UniProtKB:

A6HNG9 (UniProtKB/TrEMBL), A0A8I6ABA5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQLVLKMDSSPDNDSWLEDQWERWLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAG
LLSAGSSGSAGSRLQAEMLQMDLIDAASDTPGAEDDEEDDDELAAQRPGVGPSKAESGQEPASR
SQGQGQGPGTGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQ
TPPHEHICLSDELPPQGSPVPTQDRGTSTDSPCRRTAATQMAPPSGPPATAPGGRGHSHRDRIH
YQADVRLEATEEIYLTPVQRPPDPAEPTSTFLPPTESRMSVSSDPDPAAYSVTAGRPHPSISEE
DEGFDCLSSPEQAEPPGGGWRGSLGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSL
RPCFGDYSDESDSATVYDNCASASSPYESAIGEEYEEAPQPRPPTCLSEDSTPDEPDVHFSKKF
LNVFMSGRSRSSSAESFGLFSCVINGEEHEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDY
WYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWIDQFRVKFLGSVQVPYHKGNDVLCA
AMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADEAQEAKGNKCSHFFQLKNISFCGYHPK
NNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE

hide sequence

Ensembl Acc Id:

ENSRNOP00000074684 ⟸ ENSRNOT00000079746

RefSeq Acc Id:	XP_038960030 ⟸ XM_039104102
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038960028 ⟸ XM_039104100
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038960029 ⟸ XM_039104101
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000089891 ⟸ ENSRNOT00000111802

Ensembl Acc Id:

ENSRNOP00000090670 ⟸ ENSRNOT00000117436

Protein Domains

PID SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9R237-F1-model_v2	AlphaFold	Q9R237	1-708	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:70937	AgrOrtholog
BioCyc Gene	G2FUF-48699	BioCyc
Ensembl Genes	ENSRNOG00000058478	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000079746	ENTREZGENE
	ENSRNOT00000079746.2	UniProtKB/Swiss-Prot
	ENSRNOT00000111802	ENTREZGENE
	ENSRNOT00000117436.1	UniProtKB/Swiss-Prot
Gene3D-CATH	2.30.29.30	UniProtKB/Swiss-Prot
	SH3 Domains	UniProtKB/Swiss-Prot
InterPro	JIP1_scaffold	UniProtKB/Swiss-Prot
	JIP1_SH3	UniProtKB/Swiss-Prot
	PH-like_dom_sf	UniProtKB/Swiss-Prot
	PTB/PI_dom	UniProtKB/Swiss-Prot
	SH3-like_dom_sf	UniProtKB/Swiss-Prot
	SH3_domain	UniProtKB/Swiss-Prot
KEGG Report	rno:116457	UniProtKB/Swiss-Prot
NCBI Gene	116457	ENTREZGENE
PANTHER	C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 1	UniProtKB/Swiss-Prot
	JNK-INTERACTING PROTEIN 1-LIKE PROTEIN	UniProtKB/Swiss-Prot
Pfam	PID	UniProtKB/Swiss-Prot
	SH3_9	UniProtKB/Swiss-Prot
PhenoGen	Mapk8ip1	PhenoGen
PROSITE	PID	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000058478	RatGTEx
SMART	PTB	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
Superfamily-SCOP	PH domain-like	UniProtKB/Swiss-Prot
	SSF50044	UniProtKB/Swiss-Prot
UniProt	A0A8I6ABA5	ENTREZGENE, UniProtKB/TrEMBL
	A6HNG8	ENTREZGENE, UniProtKB/TrEMBL
	A6HNG9	ENTREZGENE, UniProtKB/TrEMBL
	A6HNH0	ENTREZGENE, UniProtKB/TrEMBL
	B0VXR5	ENTREZGENE
	JIP1_RAT	UniProtKB/Swiss-Prot
	O88979	ENTREZGENE
	Q9R1H8	ENTREZGENE
	Q9R237	ENTREZGENE
	Q9WVI5	ENTREZGENE
	Q9WVI6	ENTREZGENE
UniProt Secondary	B0VXR5	UniProtKB/Swiss-Prot
	O88979	UniProtKB/Swiss-Prot
	Q9R1H8	UniProtKB/Swiss-Prot
	Q9WVI5	UniProtKB/Swiss-Prot
	Q9WVI6	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-18	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	Mapk8ip	mitogen activated protein kinase 8 interacting protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2003-04-09	Mapk8ip	mitogen activated protein kinase 8 interacting protein			Symbol and Name updated	629477	APPROVED
2003-03-12	Mapk8ip	mitogen activated protein kinase 8 interacting protein	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	Data merged from RGD:621049	628472	PROVISIONAL
2002-08-07	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1			Symbol and Name status set to provisional	70820	PROVISIONAL
2002-07-09	Mapk8ip	mitogen activated protein kinase 8 interacting protein			Symbol and Name updated to reflect Human and Mouse nomenclature	70877	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains a putative phosphotyrosine interaction domain, a helix-loop-helix domain, and an SH3 homologous region	70789
gene_expression	mRNA expressed in brain and kidney	70789

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)