Klhl17 (kelch-like family member 17) - Rat Genome Database

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Gene: Klhl17 (kelch-like family member 17) Rattus norvegicus
Analyze
Symbol: Klhl17
Name: kelch-like family member 17
RGD ID: 708444
Description: Enables POZ domain binding activity; actin filament binding activity; and molecular adaptor activity. Involved in actin cytoskeleton organization and regulation protein catabolic process at postsynapse. Located in actin cytoskeleton; dendrite cytoplasm; and neuronal cell body. Is active in glutamatergic synapse and postsynapse. Orthologous to human KLHL17 (kelch like family member 17); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: actinfilin; kelch-like 17; kelch-like 17 (Drosophila); kelch-like protein 17; LOC246757
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85172,095,701 - 172,101,945 (-)NCBIGRCr8
mRatBN7.25166,813,482 - 166,819,949 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,814,110 - 166,818,925 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5169,515,574 - 169,521,068 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,336,958 - 171,342,452 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05171,299,519 - 171,305,012 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,654,238 - 173,659,706 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,654,860 - 173,659,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05177,128,278 - 177,134,602 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45173,064,739 - 173,069,548 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15173,075,233 - 173,080,043 (-)NCBI
Celera5165,015,955 - 165,020,764 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Interactions between CAP70 and actinfilin are important for integrity of actin cytoskeleton structures in neurons. Chen Y and Li M, Neuropharmacology. 2005 Dec;49(7):1026-41. Epub 2005 Jul 28.
2. Actinfilin, a Brain-specific Actin-binding Protein in Postsynaptic Density. Chen Y, etal., J Biol Chem 2002 Aug 23;277(34):30495-501.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Autism-related KLHL17 and SYNPO act in concert to control activity-dependent dendritic spine enlargement and the spine apparatus. Hu HT, etal., PLoS Biol. 2023 Aug 31;21(8):e3002274. doi: 10.1371/journal.pbio.3002274. eCollection 2023 Aug.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Actinfilin is a Cul3 substrate adaptor, linking GluR6 kainate receptor subunits to the ubiquitin-proteasome pathway. Salinas GD, etal., J Biol Chem. 2006 Dec 29;281(52):40164-73. Epub 2006 Oct 24.
Additional References at PubMed
PMID:22664934  


Genomics

Comparative Map Data
Klhl17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85172,095,701 - 172,101,945 (-)NCBIGRCr8
mRatBN7.25166,813,482 - 166,819,949 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,814,110 - 166,818,925 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5169,515,574 - 169,521,068 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05171,336,958 - 171,342,452 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05171,299,519 - 171,305,012 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,654,238 - 173,659,706 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,654,860 - 173,659,675 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05177,128,278 - 177,134,602 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45173,064,739 - 173,069,548 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15173,075,233 - 173,080,043 (-)NCBI
Celera5165,015,955 - 165,020,764 (-)NCBICelera
Cytogenetic Map5q36NCBI
KLHL17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381960,584 - 965,719 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1960,584 - 965,719 (+)EnsemblGRCh38hg38GRCh38
GRCh371895,964 - 901,099 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361885,830 - 890,958 (+)NCBINCBI36Build 36hg18NCBI36
Build 341936,109 - 941,162NCBI
Celera11,690,578 - 1,695,031 (-)NCBICelera
Cytogenetic Map1p36.33NCBI
HuRef1166,390 - 170,737 (+)NCBIHuRef
CHM1_11883,012 - 888,029 (+)NCBICHM1_1
T2T-CHM13v2.01389,374 - 394,430 (+)NCBIT2T-CHM13v2.0
Klhl17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394156,313,501 - 156,319,314 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4156,313,792 - 156,319,314 (-)EnsemblGRCm39 Ensembl
GRCm384156,229,044 - 156,234,857 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4156,221,456 - 156,234,857 (-)EnsemblGRCm38mm10GRCm38
MGSCv374155,603,153 - 155,608,966 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364155,603,466 - 155,608,945 (-)NCBIMGSCv36mm8
Celera4158,485,528 - 158,491,396 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map488.63NCBI
Klhl17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,745,162 - 9,750,874 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554869,745,162 - 9,750,874 (-)NCBIChiLan1.0ChiLan1.0
KLHL17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21227,297,335 - 227,303,339 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,994,101 - 226,000,446 (-)NCBINHGRI_mPanPan1
PanPan1.11859,736 - 864,476 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1859,730 - 864,476 (+)Ensemblpanpan1.1panPan2
KLHL17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,186,077 - 56,193,671 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,187,922 - 56,192,983 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,264,141 - 56,271,730 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,389,363 - 56,397,191 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,389,214 - 56,396,503 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,380,471 - 56,388,286 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,272,408 - 56,280,204 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0556,662,426 - 56,670,222 (+)NCBIUU_Cfam_GSD_1.0
Klhl17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,379,695 - 27,385,239 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367372,079,582 - 2,086,152 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367372,080,699 - 2,086,252 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,322,184 - 63,328,259 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,320,898 - 63,328,093 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2657,898,263 - 57,901,884 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,467,286 - 130,472,384 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20130,467,261 - 130,471,904 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605435,097,403 - 35,102,481 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248188,546,137 - 8,550,603 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248188,545,562 - 8,551,348 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Klhl17
10 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:92
Count of miRNA genes:82
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000027547
Prediction methods:Microtar, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000027547   ⟹   ENSRNOP00000027547
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5166,814,110 - 166,818,925 (-)Ensembl
Rnor_6.0 Ensembl5173,654,860 - 173,659,675 (-)Ensembl
RefSeq Acc Id: NM_145671   ⟹   NP_663704
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,701 - 172,101,195 (-)NCBI
mRatBN7.25166,813,482 - 166,818,976 (-)NCBI
Rnor_6.05173,654,860 - 173,659,669 (-)NCBI
Rnor_5.05177,128,278 - 177,134,602 (-)NCBI
RGSC_v3.45173,064,739 - 173,069,548 (-)RGD
Celera5165,015,955 - 165,020,764 (-)RGD
Sequence:
RefSeq Acc Id: XM_006239521   ⟹   XP_006239583
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,707 - 172,101,117 (-)NCBI
mRatBN7.25166,813,494 - 166,818,956 (-)NCBI
Rnor_6.05173,654,238 - 173,659,706 (-)NCBI
Rnor_5.05177,128,278 - 177,134,602 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008764336   ⟹   XP_008762558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,707 - 172,101,117 (-)NCBI
mRatBN7.25166,813,494 - 166,818,956 (-)NCBI
Rnor_6.05173,654,238 - 173,659,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109280   ⟹   XP_038965208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,707 - 172,101,945 (-)NCBI
mRatBN7.25166,813,494 - 166,819,831 (-)NCBI
RefSeq Acc Id: XM_039109282   ⟹   XP_038965210
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,096,908 - 172,101,117 (-)NCBI
mRatBN7.25166,814,689 - 166,818,956 (-)NCBI
RefSeq Acc Id: XM_039109283   ⟹   XP_038965211
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,096,908 - 172,101,117 (-)NCBI
mRatBN7.25166,814,689 - 166,818,956 (-)NCBI
RefSeq Acc Id: XM_063287161   ⟹   XP_063143231
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85172,095,707 - 172,101,117 (-)NCBI
RefSeq Acc Id: NP_663704   ⟸   NM_145671
- UniProtKB: Q8K430 (UniProtKB/Swiss-Prot),   A6IUX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239583   ⟸   XM_006239521
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008762558   ⟸   XM_008764336
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000027547   ⟸   ENSRNOT00000027547
RefSeq Acc Id: XP_038965208   ⟸   XM_039109280
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038965211   ⟸   XM_039109283
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038965210   ⟸   XM_039109282
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063143231   ⟸   XM_063287161
- Peptide Label: isoform X3
Protein Domains
BACK   BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K430-F1-model_v2 AlphaFold Q8K430 1-640 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694348
Promoter ID:EPDNEW_R4872
Type:single initiation site
Name:Klhl17_1
Description:kelch-like family member 17
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05173,659,719 - 173,659,779EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708444 AgrOrtholog
BioCyc Gene G2FUF-38856 BioCyc
Ensembl Genes ENSRNOG00000020302 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055015352 UniProtKB/Swiss-Prot
  ENSRNOG00060004853 UniProtKB/Swiss-Prot
  ENSRNOG00065010691 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027547.6 UniProtKB/Swiss-Prot
  ENSRNOT00055026221 UniProtKB/Swiss-Prot
  ENSRNOT00060008077 UniProtKB/Swiss-Prot
  ENSRNOT00065017311 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gal_Oxase/kelch_b-propeller UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:246757 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 246757 ENTREZGENE
PANTHER BTB DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KELCH PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KELCH-LIKE PROTEIN 17 UniProtKB/TrEMBL
  KELCH-LIKE PROTEIN DIABLO UniProtKB/TrEMBL
  LD33804P UniProtKB/TrEMBL
Pfam BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Klhl17 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS KELCHREPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020302 RatGTEx
  ENSRNOG00055015352 RatGTEx
  ENSRNOG00060004853 RatGTEx
  ENSRNOG00065010691 RatGTEx
SMART BACK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BTB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kelch UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Galactose oxidase, central domain UniProtKB/TrEMBL
  Kelch motif UniProtKB/TrEMBL
  POZ domain UniProtKB/TrEMBL
  SSF50965 UniProtKB/Swiss-Prot
  SSF54695 UniProtKB/Swiss-Prot
UniProt A6IUX0 ENTREZGENE, UniProtKB/TrEMBL
  A6IUX1_RAT UniProtKB/TrEMBL
  A6IUX2_RAT UniProtKB/TrEMBL
  KLH17_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-06 Klhl17  kelch-like family member 17  Klhl17  kelch-like 17 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Klhl17  kelch-like 17 (Drosophila)  LOC246757  actinfilin  Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expression is brain-specific 625502