Pld1 (phospholipase D1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Pld1 (phospholipase D1) Mus musculus
Analyze
Symbol: Pld1
Name: phospholipase D1
RGD ID: 70830
MGI Page MGI
Description: Predicted to enable phospholipase D activity. Acts upstream of or within defense response to Gram-positive bacterium. Predicted to be located in several cellular components, including Golgi cisterna; cytoplasmic vesicle; and lamellipodium. Predicted to be active in cholinergic synapse; cytoplasmic vesicle; and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in developmental cardiac valvular defect. Orthologous to human PLD1 (phospholipase D1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AA536939; C85393; choline phosphatase 1; mPLD1; phosphatidylcholine-hydrolyzing phospholipase D1; Pl; Pld; PLD 1; Pld1a; Pld1b
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39327,992,636 - 28,187,388 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl327,992,844 - 28,187,511 (+)EnsemblGRCm39 Ensembl
GRCm38327,938,459 - 28,133,362 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl327,938,695 - 28,133,362 (+)EnsemblGRCm38mm10GRCm38
MGSCv37327,837,602 - 28,032,284 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36328,215,231 - 28,324,307 (+)NCBIMGSCv36mm8
Celera327,897,052 - 28,088,894 (+)NCBICelera
Cytogenetic Map3A3NCBI
cM Map311.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP,ISO)
1,2-dimethylhydrazine  (EXP)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,3-bisphospho-D-glyceric acid  (ISO)
2,3-bisphosphoglyceric acid  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-naphthylamine  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
5-aza-2'-deoxycytidine  (ISO)
8-Br-cAMP  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butan-1-ol  (EXP,ISO)
cadmium atom  (ISO)
caffeine  (ISO)
cannabidiol  (EXP)
cannabigerol  (EXP)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
cypermethrin  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
fenvalerate  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
furan  (ISO)
ganglioside GM1  (ISO)
genistein  (ISO)
glyphosate  (EXP,ISO)
Goe 6976  (ISO)
hexadecanoic acid  (ISO)
hydrogen cyanide  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
irinotecan  (ISO)
isoprenaline  (EXP)
Licochalcone B  (ISO)
lithium chloride  (ISO)
lithocholic acid  (EXP)
melanins  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
metformin  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury(1+)  (ISO)
mifepristone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nicotine  (ISO)
nitrofen  (ISO)
oleic acid  (ISO)
oxaliplatin  (ISO)
oxycodone  (ISO)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phenylarsine oxide  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidic acid  (ISO)
pinostrobin  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP)
potassium chromate  (ISO)
potassium cyanide  (EXP)
progesterone  (EXP)
propiconazole  (EXP)
prostaglandin E2  (ISO)
pyrethrins  (ISO)
quercetin  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
rottlerin  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
senecionine  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
Soman  (ISO)
sotorasib  (ISO)
sulforaphane  (ISO)
testosterone  (EXP,ISO)
tetracycline  (EXP)
titanium dioxide  (EXP)
topiramate  (ISO)
topotecan  (ISO)
trametinib  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
troglitazone  (EXP,ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Simultaneous high expression of PLD1 and Sp1 predicts a poor prognosis for pancreatic ductal adenocarcinoma patients. Hu J, etal., Oncotarget. 2016 Nov 29;7(48):78557-78565. doi: 10.18632/oncotarget.12447.
2. Differential expression of phospholipase D isozymes in the hippocampus following kainic acid-induced seizures. Kim SY, etal., J Neuropathol Exp Neurol. 2004 Aug;63(8):812-20.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9013646   PMID:9307024   PMID:9395408   PMID:9540968   PMID:9560313   PMID:9813240   PMID:10349636   PMID:10642495   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851  
PMID:11544199   PMID:11544318   PMID:11734063   PMID:12466851   PMID:12477932   PMID:12782152   PMID:14517341   PMID:14610273   PMID:14615486   PMID:14681479   PMID:14718562   PMID:14761980  
PMID:14996723   PMID:14999815   PMID:15716416   PMID:15772157   PMID:15895362   PMID:16054594   PMID:16141072   PMID:16141073   PMID:16143829   PMID:16449385   PMID:16449386   PMID:16723731  
PMID:17085061   PMID:17213336   PMID:17720976   PMID:17936375   PMID:18198186   PMID:18519738   PMID:18541525   PMID:18636075   PMID:19276086   PMID:19652486   PMID:19864314   PMID:19884258  
PMID:19950202   PMID:19994725   PMID:20051593   PMID:20231899   PMID:20448441   PMID:20463923   PMID:20505075   PMID:21266992   PMID:21319224   PMID:21357688   PMID:21536681   PMID:21677750  
PMID:21873635   PMID:22024166   PMID:22105357   PMID:22178154   PMID:22974101   PMID:23109426   PMID:23131846   PMID:23362269   PMID:23383154   PMID:23689131   PMID:23868933   PMID:23915343  
PMID:24194600   PMID:24253251   PMID:24262632   PMID:24336713   PMID:24548427   PMID:24811005   PMID:24813107   PMID:24830864   PMID:24990946   PMID:25046440   PMID:25046692   PMID:25047119  
PMID:25187519   PMID:25428992   PMID:25489735   PMID:25967349   PMID:26122663   PMID:26335962   PMID:26392467   PMID:26437780   PMID:26782071   PMID:26916731   PMID:27299737   PMID:27627745  
PMID:27793841   PMID:27799408   PMID:27976696   PMID:28125719   PMID:28711718   PMID:28912445   PMID:29386256   PMID:29437245   PMID:29656494   PMID:29968773   PMID:30207376   PMID:30555342  
PMID:30944160   PMID:31090437   PMID:31138677   PMID:31586128   PMID:31796631   PMID:31797996   PMID:32209478   PMID:32725633   PMID:32814056   PMID:32971863   PMID:33368247   PMID:33497821  
PMID:33945837   PMID:34320341   PMID:34610470   PMID:35764123   PMID:36162649   PMID:38355793  


Genomics

Comparative Map Data
Pld1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39327,992,636 - 28,187,388 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl327,992,844 - 28,187,511 (+)EnsemblGRCm39 Ensembl
GRCm38327,938,459 - 28,133,362 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl327,938,695 - 28,133,362 (+)EnsemblGRCm38mm10GRCm38
MGSCv37327,837,602 - 28,032,284 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36328,215,231 - 28,324,307 (+)NCBIMGSCv36mm8
Celera327,897,052 - 28,088,894 (+)NCBICelera
Cytogenetic Map3A3NCBI
cM Map311.15NCBI
PLD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383171,600,404 - 171,810,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3171,600,404 - 171,810,950 (-)EnsemblGRCh38hg38GRCh38
GRCh373171,318,194 - 171,528,273 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363172,801,339 - 172,938,566 (-)NCBINCBI36Build 36hg18NCBI36
Build 343172,801,346 - 172,938,574NCBI
Celera3169,718,435 - 169,928,143 (-)NCBICelera
Cytogenetic Map3q26.31NCBI
HuRef3168,688,221 - 168,898,341 (-)NCBIHuRef
CHM1_13171,281,084 - 171,491,135 (-)NCBICHM1_1
T2T-CHM13v2.03174,384,521 - 174,594,617 (-)NCBIT2T-CHM13v2.0
Pld1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82112,777,820 - 112,975,857 (+)NCBIGRCr8
mRatBN7.22110,849,205 - 111,047,304 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2110,893,608 - 111,047,692 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2117,548,080 - 117,700,325 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02115,660,662 - 115,812,852 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02110,374,318 - 110,526,587 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02113,651,967 - 113,849,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2113,652,348 - 113,849,403 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02133,357,235 - 133,554,180 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42115,306,940 - 115,460,518 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12115,251,901 - 115,405,480 (+)NCBI
Celera2106,084,707 - 106,238,116 (+)NCBICelera
Cytogenetic Map2q24NCBI
Pld1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554201,696,751 - 1,892,741 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554201,697,716 - 1,892,741 (-)NCBIChiLan1.0ChiLan1.0
PLD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,481,152 - 169,693,135 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13169,482,578 - 169,696,377 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03168,606,342 - 168,816,383 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13176,790,736 - 176,999,974 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3176,790,753 - 176,961,033 (-)Ensemblpanpan1.1panPan2
PLD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13435,917,759 - 36,080,383 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3435,921,058 - 36,121,631 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3444,928,877 - 45,133,990 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03436,000,267 - 36,205,332 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3436,000,274 - 36,205,751 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13435,940,863 - 36,145,600 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03435,903,822 - 36,109,331 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03436,165,953 - 36,370,780 (-)NCBIUU_Cfam_GSD_1.0
Pld1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602102,572,478 - 102,777,840 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936593930,637 - 1,046,821 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936593844,634 - 1,049,478 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13110,154,874 - 110,376,294 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113110,152,268 - 110,376,319 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213119,138,285 - 119,362,303 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11517,667,079 - 17,871,452 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1517,706,030 - 17,870,266 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606326,423,171 - 26,629,555 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pld1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473049,665,432 - 49,885,184 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473049,665,432 - 49,885,242 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pld1
7335 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2276
Count of miRNA genes:672
Interacting mature miRNAs:852
Transcripts:ENSMUST00000067757, ENSMUST00000120834, ENSMUST00000123539, ENSMUST00000125338, ENSMUST00000126594, ENSMUST00000127139, ENSMUST00000131842, ENSMUST00000148827, ENSMUST00000149017
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32017486254180103Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
12904010Cfq8_mconditioned fear QTL 8 (mouse)32476823231332103Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
4142092Tgq13_mtriglyceride QTL 13 (mouse)Not determined1828816852288168Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
13432186Rotse1_mrotarod training saline/ethanol 1 (mouse)32665522728355227Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3452541938525519Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31163045345630591Mouse

Markers in Region
RH127181  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38328,132,918 - 28,133,118UniSTSGRCm38
MGSCv37328,031,840 - 28,032,040UniSTSGRCm37
Celera328,088,450 - 28,088,650UniSTS
Cytogenetic Map3A3UniSTS
cM Map310.5UniSTS
Whitehead/MRC_RH3312.65UniSTS
MHAa34f8.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38327,988,771 - 27,988,871UniSTSGRCm38
MGSCv37327,887,693 - 27,887,793UniSTSGRCm37
Celera327,947,608 - 27,947,708UniSTS
Cytogenetic Map3A3UniSTS
cM Map310.5UniSTS
Whitehead_YAC3 UniSTS
RH124503  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38328,132,921 - 28,133,159UniSTSGRCm38
MGSCv37328,031,843 - 28,032,081UniSTSGRCm37
Celera328,088,453 - 28,088,691UniSTS
Cytogenetic Map3A3UniSTS
cM Map310.5UniSTS
Pld1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38328,132,185 - 28,133,038UniSTSGRCm38
MGSCv37328,031,107 - 28,031,960UniSTSGRCm37
Celera328,087,717 - 28,088,570UniSTS
Cytogenetic Map3A3UniSTS
cM Map310.5UniSTS
fj80c09.x1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38327,959,077 - 27,959,472UniSTSGRCm38
MGSCv37327,857,999 - 27,858,394UniSTSGRCm37
Celera327,917,899 - 27,918,294UniSTS
Cytogenetic Map3A3UniSTS
cM Map310.5UniSTS


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001164056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001368667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017319491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC132149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02106243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC068144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF727963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U87868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000067757   ⟹   ENSMUSP00000064694
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,038,320 - 28,187,383 (+)Ensembl
GRCm38.p6 Ensembl327,984,171 - 28,133,234 (+)Ensembl
Ensembl Acc Id: ENSMUST00000120834   ⟹   ENSMUSP00000113810
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl327,992,844 - 28,187,388 (+)Ensembl
GRCm38.p6 Ensembl327,938,695 - 28,133,239 (+)Ensembl
Ensembl Acc Id: ENSMUST00000123539   ⟹   ENSMUSP00000118727
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,038,322 - 28,186,199 (+)Ensembl
GRCm38.p6 Ensembl327,984,173 - 28,132,050 (+)Ensembl
Ensembl Acc Id: ENSMUST00000125338   ⟹   ENSMUSP00000121318
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,004,152 - 28,082,836 (+)Ensembl
GRCm38.p6 Ensembl327,950,003 - 28,028,687 (+)Ensembl
Ensembl Acc Id: ENSMUST00000126594   ⟹   ENSMUSP00000121569
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,163,908 - 28,184,944 (+)Ensembl
GRCm38.p6 Ensembl328,109,759 - 28,130,795 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127139
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,004,151 - 28,011,549 (+)Ensembl
GRCm38.p6 Ensembl327,950,002 - 27,957,400 (+)Ensembl
Ensembl Acc Id: ENSMUST00000131842
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,123,663 - 28,140,835 (+)Ensembl
GRCm38.p6 Ensembl328,069,514 - 28,086,686 (+)Ensembl
Ensembl Acc Id: ENSMUST00000148827   ⟹   ENSMUSP00000120273
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,085,411 - 28,187,511 (+)Ensembl
GRCm38.p6 Ensembl328,031,262 - 28,133,362 (+)Ensembl
Ensembl Acc Id: ENSMUST00000149017
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,095,415 - 28,102,271 (+)Ensembl
GRCm38.p6 Ensembl328,041,266 - 28,048,122 (+)Ensembl
Ensembl Acc Id: ENSMUST00000195622
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl328,133,339 - 28,136,657 (+)Ensembl
GRCm38.p6 Ensembl328,079,190 - 28,082,508 (+)Ensembl
RefSeq Acc Id: NM_001164056   ⟹   NP_001157528
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39327,992,810 - 28,187,388 (+)NCBI
GRCm38327,938,680 - 28,133,362 (+)NCBI
MGSCv37327,837,602 - 28,032,284 (+)RGD
Celera327,897,052 - 28,088,894 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001368667   ⟹   NP_001355596
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,038,301 - 28,187,388 (+)NCBI
GRCm38327,984,171 - 28,133,362 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001410530   ⟹   NP_001397459
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39327,992,810 - 28,187,388 (+)NCBI
RefSeq Acc Id: NM_001410531   ⟹   NP_001397460
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39327,992,810 - 28,187,388 (+)NCBI
RefSeq Acc Id: NM_001410532   ⟹   NP_001397461
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39327,992,810 - 28,187,388 (+)NCBI
RefSeq Acc Id: NM_008875   ⟹   NP_032901
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,038,301 - 28,187,388 (+)NCBI
GRCm38327,984,171 - 28,133,362 (+)NCBI
MGSCv37327,837,602 - 28,032,284 (+)RGD
Celera327,897,052 - 28,088,894 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017319489   ⟹   XP_017174978
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39327,992,636 - 28,187,388 (+)NCBI
GRCm38327,938,459 - 28,133,239 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017319490   ⟹   XP_017174979
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39327,992,636 - 28,187,388 (+)NCBI
GRCm38327,938,459 - 28,133,239 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017319491   ⟹   XP_017174980
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39328,004,605 - 28,187,388 (+)NCBI
GRCm38327,951,492 - 28,133,239 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032901   ⟸   NM_008875
- Peptide Label: isoform 1
- UniProtKB: Q9Z280 (UniProtKB/Swiss-Prot),   O35911 (UniProtKB/Swiss-Prot),   Q6NVF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157528   ⟸   NM_001164056
- Peptide Label: isoform 1
- UniProtKB: Q9Z280 (UniProtKB/Swiss-Prot),   O35911 (UniProtKB/Swiss-Prot),   Q6NVF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174979   ⟸   XM_017319490
- Peptide Label: isoform X1
- UniProtKB: Q9Z280 (UniProtKB/Swiss-Prot),   O35911 (UniProtKB/Swiss-Prot),   D6RH77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174978   ⟸   XM_017319489
- Peptide Label: isoform X1
- UniProtKB: Q9Z280 (UniProtKB/Swiss-Prot),   O35911 (UniProtKB/Swiss-Prot),   D6RH77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017174980   ⟸   XM_017319491
- Peptide Label: isoform X1
- UniProtKB: Q9Z280 (UniProtKB/Swiss-Prot),   O35911 (UniProtKB/Swiss-Prot),   D6RH77 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001355596   ⟸   NM_001368667
- Peptide Label: isoform 2
- UniProtKB: Q9Z280 (UniProtKB/Swiss-Prot),   O35911 (UniProtKB/Swiss-Prot),   D6RH77 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000121318   ⟸   ENSMUST00000125338
Ensembl Acc Id: ENSMUSP00000064694   ⟸   ENSMUST00000067757
Ensembl Acc Id: ENSMUSP00000121569   ⟸   ENSMUST00000126594
Ensembl Acc Id: ENSMUSP00000113810   ⟸   ENSMUST00000120834
Ensembl Acc Id: ENSMUSP00000120273   ⟸   ENSMUST00000148827
Ensembl Acc Id: ENSMUSP00000118727   ⟸   ENSMUST00000123539
RefSeq Acc Id: NP_001397459   ⟸   NM_001410530
- Peptide Label: isoform 2
- UniProtKB: Q9Z280 (UniProtKB/Swiss-Prot),   O35911 (UniProtKB/Swiss-Prot),   D6RH77 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397460   ⟸   NM_001410531
- Peptide Label: isoform 1
- UniProtKB: Q9Z280 (UniProtKB/Swiss-Prot),   O35911 (UniProtKB/Swiss-Prot),   Q6NVF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397461   ⟸   NM_001410532
- Peptide Label: isoform 1
- UniProtKB: Q9Z280 (UniProtKB/Swiss-Prot),   O35911 (UniProtKB/Swiss-Prot),   Q6NVF2 (UniProtKB/TrEMBL)
Protein Domains
PH   PLD phosphodiesterase   PX

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z280-F1-model_v2 AlphaFold Q9Z280 1-1074 view protein structure

Promoters
RGD ID:6880370
Promoter ID:EPDNEW_M3636
Type:initiation region
Name:Pld1_1
Description:Mus musculus phospholipase D1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3637  EPDNEW_M3638  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38327,938,661 - 27,938,721EPDNEW
RGD ID:6880372
Promoter ID:EPDNEW_M3637
Type:single initiation site
Name:Pld1_3
Description:Mus musculus phospholipase D1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3636  EPDNEW_M3638  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38327,947,080 - 27,947,140EPDNEW
RGD ID:6880374
Promoter ID:EPDNEW_M3638
Type:initiation region
Name:Pld1_2
Description:Mus musculus phospholipase D1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3636  EPDNEW_M3637  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38327,984,163 - 27,984,223EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109585 AgrOrtholog
Ensembl Genes ENSMUSG00000027695 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000067757 ENTREZGENE
  ENSMUST00000067757.11 UniProtKB/TrEMBL
  ENSMUST00000120834 ENTREZGENE
  ENSMUST00000120834.8 UniProtKB/TrEMBL
  ENSMUST00000123539 ENTREZGENE
  ENSMUST00000123539.8 UniProtKB/TrEMBL
  ENSMUST00000125338.8 UniProtKB/TrEMBL
  ENSMUST00000126594.3 UniProtKB/TrEMBL
  ENSMUST00000148827.8 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endonuclease Chain A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLD-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_D/transphosphatidylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_D_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_D_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18805 UniProtKB/TrEMBL
MGD MGI:109585 ENTREZGENE
NCBI Gene 18805 ENTREZGENE
PANTHER PHOSPHOLIPASE D1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18896 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00787 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLDc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLDc_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pld1 PhenoGen
PIRSF Phospholipase_D_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50195 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PLDc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00312 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phospholipase D/nuclease UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF64268 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z2V2_MOUSE UniProtKB/TrEMBL
  D6RH77 ENTREZGENE, UniProtKB/TrEMBL
  F6QJR6_MOUSE UniProtKB/TrEMBL
  F6WKY8_MOUSE UniProtKB/TrEMBL
  O35911 ENTREZGENE
  PLD1_MOUSE UniProtKB/Swiss-Prot
  Q3UWT7_MOUSE UniProtKB/TrEMBL
  Q6NVF2 ENTREZGENE, UniProtKB/TrEMBL
  Q9Z280 ENTREZGENE
UniProt Secondary O35911 UniProtKB/Swiss-Prot