Slc5a6 (solute carrier family 5 member 6) - Rat Genome Database

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Gene: Slc5a6 (solute carrier family 5 member 6) Rattus norvegicus
Analyze
Symbol: Slc5a6
Name: solute carrier family 5 member 6
RGD ID: 69648
Description: Enables sodium-dependent multivitamin transmembrane transporter activity. Involved in biotin transport and pantothenate transmembrane transport. Located in brush border membrane. Orthologous to human SLC5A6 (solute carrier family 5 member 6); INTERACTS WITH (R)-lipoic acid; (R)-pantothenic acid; 1,2,4-trimethylbenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Na(+)-dependent multivitamin transporter; SMVT; sodium-dependent multivitamin transporter; solute carrier family 5 (sodium-dependent vitamin transporter) member 6; solute carrier family 5 (sodium-dependent vitamin transporter), member 6; solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6; solute carrier family 5, member 6
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,039,865 - 31,051,671 (+)NCBIGRCr8
mRatBN7.2625,319,187 - 25,331,713 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,320,442 - 25,331,712 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx625,621,246 - 25,632,513 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0625,937,114 - 25,948,381 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,416,026 - 25,427,321 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0626,685,823 - 26,697,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl626,686,033 - 26,697,116 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0636,499,460 - 36,512,085 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,301,630 - 25,312,901 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1625,304,582 - 25,315,853 (+)NCBI
Celera624,811,307 - 24,822,588 (+)NCBICelera
Cytogenetic Map6q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(R)-lipoic acid  (EXP,ISO)
(R)-pantothenic acid  (EXP,ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrophenol  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
arsenous acid  (ISO)
azide  (ISO)
benzo[a]pyrene  (ISO)
biotin  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
calmidazolium  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chelerythrine  (ISO)
chlorpyrifos  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dieldrin  (EXP)
dioxygen  (ISO)
epoxiconazole  (ISO)
flutamide  (EXP)
FR900359  (ISO)
genistein  (ISO)
glutathione  (EXP)
heptachlor  (EXP)
hydrogen peroxide  (ISO)
isotretinoin  (ISO)
lipoic acid  (EXP,ISO)
methimazole  (EXP)
methotrexate  (ISO)
mirex  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosomorpholine  (EXP)
ouabain  (ISO)
p-chloromercuribenzenesulfonic acid  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
PhIP  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
probenecid  (ISO)
propiconazole  (EXP)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium atom  (EXP,ISO)
staurosporine  (ISO)
sulfadimethoxine  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trifluoperazine  (ISO)
valproic acid  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Molecular characterization of the 5' regulatory region of rat sodium-dependent multivitamin transporter gene. Chatterjee NS, etal., Am J Physiol Cell Physiol 2001 Mar;280(3):C548-55.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Comparative analysis of ontogenic changes in renal and intestinal biotin transport in the rat. Nabokina SM, etal., Am J Physiol Renal Physiol 2003 Apr;284(4):F737-42.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate. Prasad PD, etal., J Biol Chem 1998 Mar 27;273(13):7501-6.
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10516089   PMID:12477932   PMID:23104561   PMID:25809983  


Genomics

Comparative Map Data
Slc5a6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8631,039,865 - 31,051,671 (+)NCBIGRCr8
mRatBN7.2625,319,187 - 25,331,713 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl625,320,442 - 25,331,712 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx625,621,246 - 25,632,513 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0625,937,114 - 25,948,381 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0625,416,026 - 25,427,321 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0626,685,823 - 26,697,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl626,686,033 - 26,697,116 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0636,499,460 - 36,512,085 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4625,301,630 - 25,312,901 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1625,304,582 - 25,315,853 (+)NCBI
Celera624,811,307 - 24,822,588 (+)NCBICelera
Cytogenetic Map6q14NCBI
SLC5A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38227,199,587 - 27,212,787 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl227,199,587 - 27,212,958 (-)EnsemblGRCh38hg38GRCh38
GRCh37227,422,455 - 27,435,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36227,275,962 - 27,288,575 (-)NCBINCBI36Build 36hg18NCBI36
Build 34227,334,109 - 27,346,722NCBI
Celera227,268,776 - 27,281,501 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef227,164,164 - 27,176,880 (-)NCBIHuRef
CHM1_1227,352,374 - 27,365,079 (-)NCBICHM1_1
T2T-CHM13v2.0227,241,206 - 27,254,815 (-)NCBIT2T-CHM13v2.0
Slc5a6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39531,193,380 - 31,206,268 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl531,193,380 - 31,206,268 (-)EnsemblGRCm39 Ensembl
GRCm38531,036,036 - 31,048,924 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl531,036,036 - 31,048,924 (-)EnsemblGRCm38mm10GRCm38
MGSCv37531,338,409 - 31,351,297 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36531,312,617 - 31,324,830 (-)NCBIMGSCv36mm8
Celera528,507,988 - 28,520,955 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map516.93NCBI
SLC5A6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21299,300,360 - 99,317,327 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A99,304,749 - 99,322,407 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A27,199,422 - 27,213,650 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A27,288,726 - 27,302,128 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A27,288,726 - 27,301,896 (-)Ensemblpanpan1.1panPan2
SLC5A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11721,181,916 - 21,194,301 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1721,031,765 - 21,193,112 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1721,073,728 - 21,086,105 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01721,502,873 - 21,515,270 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1721,351,935 - 21,515,309 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11721,189,666 - 21,202,032 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01721,200,734 - 21,213,100 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01721,247,616 - 21,259,983 (-)NCBIUU_Cfam_GSD_1.0
Slc5a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629265,489,807 - 65,506,815 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364935,338,289 - 5,349,758 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364935,338,119 - 5,349,758 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC5A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3111,922,848 - 111,930,940 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13111,919,298 - 111,930,944 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23118,917,508 - 118,929,193 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103220608
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11480,406,221 - 80,415,730 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1480,407,561 - 80,416,848 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604531,738,413 - 31,751,070 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Slc5a6
42 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:300
Count of miRNA genes:194
Interacting mature miRNAs:215
Transcripts:ENSRNOT00000009042
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6127574569Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6127574569Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6127574569Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
1359023Bp272Blood pressure QTL 2722.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)61653614027261739Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6127574569Rat

Markers in Region
RH130251  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2625,331,450 - 25,331,657 (+)MAPPERmRatBN7.2
Rnor_6.0626,696,848 - 26,697,054NCBIRnor6.0
Rnor_5.0636,511,823 - 36,512,029UniSTSRnor5.0
RGSC_v3.4625,312,639 - 25,312,845UniSTSRGSC3.4
Celera624,822,316 - 24,822,532UniSTS
RH 3.4 Map6117.9UniSTS
Cytogenetic Map6q14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001434151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_130746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC120639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF026554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF081204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF081205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF143309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF143310 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF143311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF189010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000081167   ⟹   ENSRNOP00000071291
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl625,320,478 - 25,331,710 (+)Ensembl
Rnor_6.0 Ensembl626,686,033 - 26,697,116 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082623   ⟹   ENSRNOP00000075361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl625,320,442 - 25,331,712 (+)Ensembl
Rnor_6.0 Ensembl626,686,205 - 26,696,957 (+)Ensembl
RefSeq Acc Id: NM_130746   ⟹   NP_570102
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,040,400 - 31,051,671 (+)NCBI
mRatBN7.2625,320,442 - 25,331,713 (+)NCBI
Rnor_6.0626,685,823 - 26,697,110 (+)NCBI
Rnor_5.0636,499,460 - 36,512,085 (+)NCBI
RGSC_v3.4625,301,630 - 25,312,901 (+)RGD
Celera624,811,307 - 24,822,588 (+)RGD
Sequence:
RefSeq Acc Id: XM_039111708   ⟹   XP_038967636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,039,865 - 31,051,671 (+)NCBI
mRatBN7.2625,319,908 - 25,331,713 (+)NCBI
RefSeq Acc Id: XM_039111709   ⟹   XP_038967637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,040,391 - 31,051,671 (+)NCBI
mRatBN7.2625,320,382 - 25,331,713 (+)NCBI
RefSeq Acc Id: XM_039111710   ⟹   XP_038967638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8631,040,352 - 31,051,671 (+)NCBI
mRatBN7.2625,320,378 - 25,331,713 (+)NCBI
RefSeq Acc Id: NP_570102   ⟸   NM_130746
- UniProtKB: O70247 (UniProtKB/Swiss-Prot),   B4F760 (UniProtKB/TrEMBL),   A0A8L2R3T7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075361   ⟸   ENSRNOT00000082623
Ensembl Acc Id: ENSRNOP00000071291   ⟸   ENSRNOT00000081167
RefSeq Acc Id: XP_038967636   ⟸   XM_039111708
- Peptide Label: isoform X1
- UniProtKB: O70247 (UniProtKB/Swiss-Prot),   B4F760 (UniProtKB/TrEMBL),   A0A8L2R3T7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967638   ⟸   XM_039111710
- Peptide Label: isoform X1
- UniProtKB: O70247 (UniProtKB/Swiss-Prot),   B4F760 (UniProtKB/TrEMBL),   A0A8L2R3T7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967637   ⟸   XM_039111709
- Peptide Label: isoform X1
- UniProtKB: O70247 (UniProtKB/Swiss-Prot),   B4F760 (UniProtKB/TrEMBL),   A0A8L2R3T7 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70247-F1-model_v2 AlphaFold O70247 1-634 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69648 AgrOrtholog
BioCyc Gene G2FUF-38340 BioCyc
Ensembl Genes ENSRNOG00000057628 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055018542 UniProtKB/Swiss-Prot
  ENSRNOG00060013362 UniProtKB/Swiss-Prot
  ENSRNOG00065023118 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000081167.2 UniProtKB/TrEMBL
  ENSRNOT00000082623.2 UniProtKB/Swiss-Prot
  ENSRNOT00055031528 UniProtKB/Swiss-Prot
  ENSRNOT00060022753 UniProtKB/Swiss-Prot
  ENSRNOT00065039504 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1730.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Na/Glc_symporter_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na/solute_symporter UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na/solute_symporter_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sodium:Solute_Symporter_SSF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:170551 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 170551 ENTREZGENE
PANTHER SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SSF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc5a6 PhenoGen
PROSITE NA_SOLUT_SYMP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA_SOLUT_SYMP_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000057628 RatGTEx
  ENSRNOG00055018542 RatGTEx
  ENSRNOG00060013362 RatGTEx
  ENSRNOG00065023118 RatGTEx
TIGR TC217445
UniProt A0A8L2R3T7 ENTREZGENE, UniProtKB/TrEMBL
  B4F760 ENTREZGENE, UniProtKB/TrEMBL
  O70247 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc5a6  solute carrier family 5 member 6  Slc5a6  solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-02 Slc5a6  solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6  Slc5a6  solute carrier family 5 (sodium-dependent vitamin transporter), member 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc5a6  solute carrier family 5 (sodium-dependent vitamin transporter), member 6    solute carrier family 5, member 6  Name updated 1299863 APPROVED
2002-06-10 Slc5a6  solute carrier family 5, member 6      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_protein 634 amino acid, 68.6 kDa protein 68891
gene_protein 634 amino acid, 68.6 kDa protein 68917
gene_transcript 3.2 kb transcript 68891
gene_transcript 3.2 kb transcript 68917