Mapt (microtubule-associated protein tau) - Rat Genome Database

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Gene: Mapt (microtubule-associated protein tau) Rattus norvegicus
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Symbol: Mapt
Name: microtubule-associated protein tau
RGD ID: 69329
Description: Enables several functions, including Hsp90 protein binding activity; enzyme binding activity; and protein-folding chaperone binding activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to oxidative stress; mRNA transport; and positive regulation of long-term synaptic depression. Located in several cellular components, including axon; cytoplasmic side of plasma membrane; and neuronal cell body. Used to study brain disease (multiple); cognitive disorder (multiple); obesity; and tauopathy (multiple). Biomarker of alcohol dependence; middle cerebral artery infarction; and traumatic brain injury. Human ortholog(s) of this gene implicated in dementia (multiple); neurodegenerative disease (multiple); progressive supranuclear palsy; and temporal lobe epilepsy. Orthologous to human MAPT (microtubule associated protein tau); PARTICIPATES IN Reelin signaling pathway; Alzheimer's disease pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (R)-lipoic acid; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MAPT_0N4R; MAPT_1N4R; MAPT_2N4R; MAPT_BigTau; MGC156663; microtubule-associated protein tau 0N4R; microtubule-associated protein tau 1N4R; microtubule-associated protein tau 2N4R; microtubule-associated protein tau BigTau; Mtapt; neurofibrillary tangle protein; paired helical filament-tau; PHF-tau; pTau; RNPTAU; Tau; Tau microtubule-associated protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81089,638,618 - 89,736,108 (+)NCBIGRCr8
GRCr8 Ensembl1089,638,599 - 89,736,108 (+)EnsemblGRCr8 Ensembl
mRatBN7.21089,138,644 - 89,236,137 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1089,138,627 - 89,236,129 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1094,176,204 - 94,273,767 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01093,639,716 - 93,737,291 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01089,042,500 - 89,139,907 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01092,289,002 - 92,386,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1092,288,910 - 92,386,517 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01092,050,754 - 92,147,840 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41093,411,098 - 93,508,762 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1087,832,730 - 87,930,191 (+)NCBICelera
RGSC_v3.11093,425,375 - 93,523,128 (+)NCBI
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
alcohol dependence  (IEP)
Alzheimer's disease  (IDA,ISO)
Animal Disease Models  (ISO)
anxiety disorder  (ISO)
Ataxia  (ISO)
atrial fibrillation  (ISO)
Brain Hypoxia-Ischemia  (IDA)
brain ischemia  (IDA)
breast cancer  (ISO)
cardiomyopathy  (ISO)
cognitive disorder  (IDA,ISO)
Cognitive Dysfunction  (ISO)
Creutzfeldt-Jakob disease  (ISO)
dementia  (ISO)
Drug-Induced Dyskinesia  (IDA)
epilepsy  (IDA)
essential tremor  (ISO)
Experimental Autoimmune Encephalomyelitis  (IDA)
Experimental Diabetes Mellitus  (IDA)
frontotemporal dementia  (ISO)
genetic disease  (ISO)
Gliosis  (ISO)
hepatocellular carcinoma  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
intellectual disability  (ISO)
Iron Overload  (IDA)
Koolen de Vries syndrome  (ISO)
late onset Parkinson's disease  (ISO)
learning disability  (ISO)
Memory Disorders  (IDA,ISO)
middle cerebral artery infarction  (IDA,IEP,ISO)
multiple system atrophy  (ISO)
Multiple System Atrophy (MSA) with Orthostatic Hypotension  (ISO)
neurodegenerative disease  (ISO)
obesity  (IDA)
Osteoarthritis, Hip  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (IDA,ISO)
Pick's disease  (ISO)
Premature Aging  (ISO)
progressive supranuclear palsy  (ISO)
Progressive Supranuclear Palsy 1  (ISO)
Progressive Supranuclear Palsy Atypical  (ISO)
prostate cancer  (ISO)
Psychomotor Agitation  (ISO)
respiratory failure  (ISO)
semantic dementia  (ISO)
Shy-Drager Syndrome  (ISO)
Spinal Cord Injuries  (IEP)
Splenomegaly  (ISO)
Sporadic Creutzfeldt-Jakob Disease  (ISO)
syndromic intellectual disability  (ISO)
tauopathy  (IDA,ISO)
temporal lobe epilepsy  (ISO)
traumatic brain injury  (IDA,IEP)
vascular dementia  (IDA)
Weight Gain  (ISO)
Weight Loss  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R)-lipoic acid  (EXP)
(S)-colchicine  (ISO)
(Z)-ligustilide  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (ISO)
1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea  (ISO)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,5-hexanedione  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methyl-6-(phenylethynyl)pyridine  (EXP)
2-methylcholine  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-nitropropanoic acid  (EXP)
3-phosphoglyceric acid  (ISO)
3alpha-hydroxy-5beta-pregnan-20-one  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxypsoralen  (ISO)
5alpha-pregnane-3,20-dione  (EXP)
6-propyl-2-thiouracil  (EXP)
7H-xanthine  (ISO)
8-azaguanine  (ISO)
8-Br-cAMP  (ISO)
9H-xanthine  (ISO)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (EXP,ISO)
ADP  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
agmatine  (ISO)
albendazole  (ISO)
aldehydo-D-glucose  (ISO)
alexidine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-D-galactose  (ISO)
aluminium atom  (EXP)
aluminium hydroxide  (ISO)
aluminium sulfate (anhydrous)  (EXP)
aluminium(0)  (EXP)
ammonium chloride  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
arachidonic acid  (ISO)
aristolochic acid A  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (ISO)
ascomycin  (EXP,ISO)
astemizole  (ISO)
ATP  (EXP,ISO)
benfotiamine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
berberine  (EXP)
beta-D-fructofuranose 1,6-bisphosphate  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
Calpeptin  (EXP)
calycosin  (EXP)
camptothecin  (ISO)
cannabidiol  (EXP,ISO)
capsaicin  (ISO)
carbon nanotube  (ISO)
CCCP  (EXP)
CGP 52608  (ISO)
chelidonine  (ISO)
chlordecone  (ISO)
chloroquine  (EXP,ISO)
chlorpyrifos  (ISO)
cholesterol  (EXP)
chromium atom  (ISO)
ciclopirox  (ISO)
ciguatoxin CTX1B  (ISO)
cilostazol  (ISO)
citric acid  (ISO)
clotrimazole  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
cordycepin  (EXP,ISO)
coumarin  (ISO)
curcumin  (ISO)
cyanidin cation  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cypermethrin  (EXP,ISO)
D-aspartic acid  (EXP)
D-fructofuranose 1,6-bisphosphate  (ISO)
D-glucopyranose 6-phosphate  (ISO)
D-glucose  (ISO)
daunorubicin  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
diaziquone  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diethyl phthalate  (EXP)
diethylstilbestrol  (EXP)
dihydrolipoic acid  (ISO)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dioxygen  (ISO)
dipicolinic acid  (ISO)
dizocilpine maleate  (EXP,ISO)
donepezil hydrochloride  (EXP)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (EXP)
emetine  (ISO)
emodin  (ISO)
endosulfan  (EXP,ISO)
ethanol  (ISO)
ethylparaben  (ISO)
fasudil  (EXP)
fenbendazole  (ISO)
fisetin  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
Formyl-N-acetyl-5-methoxykynurenamine  (EXP)
FR900359  (ISO)
fructose  (EXP)
fulvestrant  (ISO)
fumaric acid  (ISO)
galactose  (ISO)
genistein  (EXP)
gentamycin  (EXP)
Gentiopicrin  (ISO)
glucose  (ISO)
glyceraldehyde 3-phosphate  (ISO)
glycerol 1-phosphate  (ISO)
glyoxal  (ISO)
griseofulvin  (ISO)
harmine  (ISO)
heparin  (ISO)
hydrogen peroxide  (ISO)
IMP  (ISO)
indole-3-methanol  (EXP)
ionomycin  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (EXP)
Isobavachin  (ISO)
ivermectin  (ISO)
ketamine  (ISO)
keto-D-fructose 1,6-bisphosphate  (ISO)
kynurenine  (ISO)
L-arginine  (ISO)
L-ascorbic acid  (EXP)
L-aspartic acid  (ISO)
L-cysteine  (ISO)
L-isoleucine  (ISO)
L-lysine  (ISO)
L-phenylalanine  (ISO)
L-serine  (EXP)
L-tryptophan  (ISO)
lansoprazole  (ISO)
lasalocid  (ISO)
lead diacetate  (EXP,ISO)
lead tetraacetate  (ISO)
lead(0)  (EXP,ISO)
leflunomide  (ISO)
lipoic acid  (EXP)
liraglutide  (ISO)
lithium atom  (ISO)
lithium chloride  (EXP,ISO)
lithium hydride  (ISO)
losartan  (EXP)
LY294002  (ISO)
malic acid  (ISO)
malonaldehyde  (ISO)
maneb  (ISO)
manganese(II) chloride  (EXP)
mebendazole  (ISO)
melatonin  (EXP,ISO)
mercury dichloride  (ISO)
metformin  (ISO)
methamphetamine  (EXP,ISO)
methimazole  (EXP)
methylene blue  (ISO)
methylglyoxal  (ISO)
methylmercury chloride  (EXP,ISO)
methylseleninic acid  (ISO)
microcystin LF  (ISO)
microcystin-LR  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (ISO)
morphine  (EXP)
Morroniside  (ISO)
mycophenolic acid  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-D-aspartic acid  (ISO)
N-nitrosodiethylamine  (EXP)
N-phosphocreatine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
nocodazole  (ISO)
norethisterone  (ISO)
O-phosphoserine  (ISO)
O-propanoyl-L-carnitine  (ISO)
okadaic acid  (EXP,ISO)
oxaliplatin  (EXP)
oxidopamine  (EXP)
ozone  (ISO)
paclitaxel  (EXP,ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
pentetrazol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
Pf-06840003  (ISO)
phenylarsine oxide  (EXP,ISO)
PhIP  (ISO)
phosgene  (ISO)
phosphoenolpyruvate  (ISO)
picoxystrobin  (ISO)
piericidin A  (ISO)
pirinixic acid  (ISO)
PNU-282987  (ISO)
podophyllotoxin  (ISO)
potassium chloride  (EXP)
pravastatin  (EXP,ISO)
proanthocyanidin  (EXP)
progesterone  (EXP)
propanal  (ISO)
pyrithione  (EXP)
pyrrolidine dithiocarbamate  (ISO)
pyruvic acid  (ISO)
quercetin  (EXP,ISO)
quinolinic acid  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
Ro 31-8220  (ISO)
rotenone  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
sarin  (ISO)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
scopolamine  (EXP)
selenium atom  (EXP)
serpentine asbestos  (ISO)
sertraline  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (EXP)
staurosporine  (EXP,ISO)
streptozocin  (EXP,ISO)
succinic acid  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tadalafil  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (EXP)
tebufenpyrad  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
tetrathiomolybdate(2-)  (ISO)
thapsigargin  (EXP)
threonic acid  (ISO)
titanium dioxide  (EXP,ISO)
tolonium chloride  (ISO)
topotecan  (EXP)
tributylstannane  (EXP,ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
Tryptanthrine  (ISO)
valine  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
WIN 55212-2  (ISO)
wortmannin  (ISO)
Y-27632  (EXP)
zaragozic acid A  (EXP,ISO)
zinc acetate  (ISO)
zinc atom  (EXP)
zinc sulfate  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult walking behavior  (ISO)
amyloid fibril formation  (ISO)
axo-dendritic transport  (ISO)
axon extension  (ISO)
axonogenesis  (ISO)
DNA damage response  (ISO)
female pregnancy  (IEP)
intracellular distribution of mitochondria  (ISO)
intrinsic apoptotic signaling pathway in response to oxidative stress  (IDA)
learning or memory  (ISO)
memory  (IEP,ISO)
microtubule cytoskeleton organization  (IBA,ISO,ISS)
microtubule polymerization  (ISO)
microtubule-based process  (NAS)
mitochondrion transport along microtubule  (ISO)
mRNA transport  (IMP)
negative regulation of establishment of protein localization to mitochondrion  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of intracellular transport  (ISO)
negative regulation of mitochondrial fission  (ISO)
negative regulation of mitochondrial membrane potential  (ISO)
negative regulation of tubulin deacetylation  (ISO)
neuron differentiation  (NAS)
neuron migration  (ISO)
neuron projection development  (IBA)
positive regulation of axon extension  (ISO,ISS)
positive regulation of long-term synaptic depression  (IMP)
positive regulation of microtubule polymerization  (ISO,ISS)
positive regulation of neuron projection development  (IMP)
positive regulation of protein localization  (ISO)
positive regulation of protein localization to synapse  (ISO)
positive regulation of superoxide anion generation  (ISO)
protein homooligomerization  (ISO)
protein polymerization  (ISO)
regulation of autophagy  (ISO)
regulation of calcium-mediated signaling  (ISO)
regulation of cellular response to heat  (ISO)
regulation of microtubule cytoskeleton organization  (ISO)
regulation of microtubule polymerization or depolymerization  (ISO)
regulation of microtubule-based movement  (ISO)
response to ethanol  (IEP)
response to lead ion  (IDA)
response to nutrient  (IDA)
supramolecular fiber organization  (ISO)
synapse assembly  (ISO)
synapse organization  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. An association study of common variation at the MAPT locus with late-onset Alzheimer's disease. Abraham R, etal., Am J Med Genet B Neuropsychiatr Genet. 2009 Dec 5;150B(8):1152-5. doi: 10.1002/ajmg.b.30951.
2. The CSF neurofilament light signature in rapidly progressive neurodegenerative dementias. Abu-Rumeileh S, etal., Alzheimers Res Ther. 2018 Jan 11;10(1):3. doi: 10.1186/s13195-017-0331-1.
3. Diagnostic value of surrogate CSF biomarkers for Creutzfeldt-Jakob disease in the era of RT-QuIC. Abu-Rumeileh S, etal., J Neurol. 2019 Dec;266(12):3136-3143. doi: 10.1007/s00415-019-09537-0. Epub 2019 Sep 20.
4. Impairment of Rat Spatial Learning and Memory in a New Model of Cold Water-Induced Chronic Hypothermia: Implication for Alzheimer's Disease. Ahmadian-Attari MM, etal., Neurotox Res. 2015 Aug;28(2):95-107. doi: 10.1007/s12640-015-9525-0. Epub 2015 Mar 18.
5. Effect of MAPT and APOE on prognosis of progressive supranuclear palsy. Baba Y, etal., Neurosci Lett. 2006 Sep 11;405(1-2):116-9. Epub 2006 Jul 12.
6. Rb binding protein Che-1 interacts with Tau in cerebellar granule neurons. Modulation during neuronal apoptosis. Barbato C, etal., Mol Cell Neurosci. 2003 Dec;24(4):1038-50.
7. Interaction of Tau with Fe65 links tau to APP. Barbato C, etal., Neurobiol Dis. 2005 Mar;18(2):399-408.
8. Involvement of glucose related energy crisis and endoplasmic reticulum stress: Insinuation of streptozotocin induced Alzheimer's like pathology. Biswas J, etal., Cell Signal. 2018 Jan;42:211-226. doi: 10.1016/j.cellsig.2017.10.018. Epub 2017 Nov 7.
9. Role of Endoplasmic Reticulum Stress in Learning and Memory Impairment and Alzheimer's Disease-Like Neuropathology in the PS19 and APPSwe Mouse Models of Tauopathy and Amyloidosis. Briggs DI, etal., eNeuro. 2017 Jul 14;4(4). pii: eN-NWR-0025-17. doi: 10.1523/ENEURO.0025-17.2017. eCollection 2017 Jul-Aug.
10. Pattern of tau isoforms expression during development in vivo. Bullmann T, etal., Int J Dev Neurosci. 2009 Oct;27(6):591-7. doi: 10.1016/j.ijdevneu.2009.06.001. Epub 2009 Jun 18.
11. The PSP-associated MAPT H1 subhaplotype in Guadeloupean atypical parkinsonism. Camuzat A, etal., Mov Disord. 2008 Dec 15;23(16):2384-91. doi: 10.1002/mds.22297.
12. Hyperphosphorylation of microtubule-associated protein tau in senescence-accelerated mouse (SAM). Canudas AM, etal., Mech Ageing Dev. 2005 Dec;126(12):1300-4. Epub 2005 Sep 19.
13. The effect of Scutellaria baicalensis stem-leaf flavonoids on spatial learning and memory in chronic cerebral ischemia-induced vascular dementia of rats. Cao Y, etal., Acta Biochim Biophys Sin (Shanghai). 2016 May;48(5):437-46. doi: 10.1093/abbs/gmw024.
14. The nitration of tau protein in neurone-like PC12 cells. Cappelletti G, etal., FEBS Lett 2004 Mar 26;562(1-3):35-9.
15. The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule. Carrettiero DC, etal., J Neurosci. 2009 Feb 18;29(7):2151-61. doi: 10.1523/JNEUROSCI.4660-08.2009.
16. PTU-induced hypothyroidism in rats leads to several early neuropathological signs of Alzheimer's disease in the hippocampus and spatial memory impairments. Chaalal A, etal., Hippocampus. 2014 Nov;24(11):1381-93. doi: 10.1002/hipo.22319. Epub 2014 Jul 22.
17. A role for FKBP52 in Tau protein function. Chambraud B, etal., Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2658-63. doi: 10.1073/pnas.0914957107. Epub 2010 Jan 25.
18. Tau acts as an independent genetic risk factor in pathologically proven PD. Charlesworth G, etal., Neurobiol Aging. 2012 Apr;33(4):838.e7-11. doi: 10.1016/j.neurobiolaging.2011.11.001. Epub 2012 Jan 4.
19. Specific tau phosphorylation sites in hippocampus correlate with impairment of step-down inhibitory avoidance task in rats. Chen YG Behav Brain Res. 2005 Mar 30;158(2):277-84.
20. Toll like receptor 4 activation can be either detrimental or beneficial following mild repetitive traumatic brain injury depending on timing of activation. Corrigan F, etal., Brain Behav Immun. 2017 Aug;64:124-139. doi: 10.1016/j.bbi.2017.04.006. Epub 2017 Apr 13.
21. Impaired glutamate transport in a mouse model of tau pathology in astrocytes. Dabir DV, etal., J Neurosci. 2006 Jan 11;26(2):644-54.
22. The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells. Esposito G, etal., J Mol Med. 2006 Mar;84(3):253-8. Epub 2005 Dec 31.
23. Different MAPT haplotypes are associated with Parkinson's disease and progressive supranuclear palsy. Ezquerra M, etal., Neurobiol Aging. 2011 Mar;32(3):547.e11-6. doi: 10.1016/j.neurobiolaging.2009.09.011. Epub 2009 Oct 29.
24. Interaction of microtubule-associated protein-2 and p63: a new link between microtubules and rough endoplasmic reticulum membranes in neurons. Farah CA, etal., J Biol Chem. 2005 Mar 11;280(10):9439-49. Epub 2004 Dec 28.
25. Apoptotic effect of caspase-3 cleaved tau in hippocampal neurons and its potentiation by tau FTDP-mutation N279K. Fasulo L, etal., J Alzheimers Dis. 2005 Feb;7(1):3-13.
26. Microtubule formation and neurite growth in cerebellar macroneurons which develop in vitro: evidence for the involvement of the microtubule-associated proteins, MAP-1a, HMW-MAP2 and Tau. Ferreira A, etal., Brain Res Dev Brain Res. 1989 Oct 1;49(2):215-28.
27. H1-MAPT and the risk for familial essential tremor. Garcia-Martin E, etal., PLoS One. 2012;7(7):e41581. doi: 10.1371/journal.pone.0041581. Epub 2012 Jul 23.
28. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
29. Tau Oligomers Derived from Traumatic Brain Injury Cause Cognitive Impairment and Accelerate Onset of Pathology in Htau Mice. Gerson J, etal., J Neurotrauma. 2016 Nov 15;33(22):2034-2043. doi: 10.1089/neu.2015.4262. Epub 2016 Apr 22.
30. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
31. Reduced binding of protein phosphatase 2A to tau protein with frontotemporal dementia and parkinsonism linked to chromosome 17 mutations. Goedert M, etal., J Neurochem. 2000 Nov;75(5):2155-62.
32. Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system. Goedert M, etal., Proc Natl Acad Sci U S A 1992 Mar 1;89(5):1983-7.
33. Activation of PP2A-like phosphatase and modulation of tau phosphorylation accompany stress-induced apoptosis in cultured oligodendrocytes. Goldbaum O and Richter-Landsberg C, Glia. 2002 Dec;40(3):271-82.
34. Expression pattern of Tau in the rat brain during pregnancy and the beginning of lactation. Gonzalez-Arenas A, etal., Brain Res Bull. 2012 Nov 1;89(3-4):108-14. doi: 10.1016/j.brainresbull.2012.07.011. Epub 2012 Aug 3.
35. Altered behavior of adult obese rats by monosodium l-glutamate neonatal treatment is related to hypercorticosteronemia and activation of hypothalamic ERK1 and ERK2. Guimarães ED, etal., Nutr Neurosci. 2017 Apr;20(3):153-160. doi: 10.1179/1476830515Y.0000000004. Epub 2016 Mar 2.
36. Microtubule association of the neuronal p35 activator of Cdk5. Hou Z, etal., J Biol Chem. 2007 Jun 29;282(26):18666-70. Epub 2007 May 9.
37. Antioxidative and Neuroprotective Effects of Curcumin in an Alzheimer's Disease Rat Model Co-Treated with Intracerebroventricular Streptozotocin and Subcutaneous D-Galactose. Huang HC, etal., J Alzheimers Dis. 2016 Apr 5;52(3):899-911. doi: 10.3233/JAD-150872.
38. Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Hutton M, etal., Nature 1998 Jun 18;393(6686):702-5.
39. Mutational analysis in early-onset familial dementia in the Japanese population. The role of PSEN1 and MAPT R406W mutations. Ikeuchi T, etal., Dement Geriatr Cogn Disord. 2008;26(1):43-9. doi: 10.1159/000141483. Epub 2008 Jun 28.
40. The spice sage and its active ingredient rosmarinic acid protect PC12 cells from amyloid-beta peptide-induced neurotoxicity. Iuvone T, etal., J Pharmacol Exp Ther. 2006 Jun;317(3):1143-9. Epub 2006 Feb 22.
41. Microtubule bundling by tau proteins in vivo: analysis of functional domains. Kanai Y, etal., EMBO J. 1992 Nov;11(11):3953-61.
42. Cerebrospinal fluid neurofilament light in suspected sporadic Creutzfeldt-Jakob disease. Kanata E, etal., J Clin Neurosci. 2019 Feb;60:124-127. doi: 10.1016/j.jocn.2018.09.031. Epub 2018 Oct 9.
43. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
44. Tau binds to the distal axon early in development of polarity in a microtubule- and microfilament-dependent manner. Kempf M, etal., J Neurosci. 1996 Sep 15;16(18):5583-92.
45. Microtubule-associated protein tau is essential for long-term depression in the hippocampus. Kimura T, etal., Philos Trans R Soc Lond B Biol Sci. 2013 Dec 2;369(1633):20130144. doi: 10.1098/rstb.2013.0144. Print 2014 Jan 5.
46. Pronounced microgliosis and neurodegeneration in aged rats after tau gene transfer. Klein RL, etal., Neurobiol Aging. 2010 Dec;31(12):2091-102. doi: 10.1016/j.neurobiolaging.2008.12.002. Epub 2009 Jan 19.
47. Aging Does Not Affect Axon Initial Segment Structure and Somatic Localization of Tau Protein in Hippocampal Neurons of Fischer 344 Rats. Kneynsberg A and Kanaan NM, eNeuro. 2017 Jul 21;4(4). pii: eN-NRS-0043-17. doi: 10.1523/ENEURO.0043-17.2017. eCollection 2017 Jul-Aug.
48. Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease. Kopke E, etal., J Biol Chem. 1993 Nov 15;268(32):24374-84.
49. Intrafamilial clinical phenotypic heterogeneity with MAPT gene splice site IVS10+16C>T mutation. Larner AJ J Neurol Sci. 2009 Dec 15;287(1-2):253-6. doi: 10.1016/j.jns.2009.08.063. Epub 2009 Sep 18.
50. Genetic analysis of MAPT haplotype diversity in frontotemporal dementia. Laws SM, etal., Neurobiol Aging. 2008 Aug;29(8):1276-8. Epub 2007 Mar 26.
51. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Lewis J, etal., Science 2001 Aug 24;293(5534):1487-91.
52. Green tea polyphenols protect against okadaic acid-induced acute learning and memory impairments in rats. Li H, etal., Nutrition. 2014 Mar;30(3):337-42. doi: 10.1016/j.nut.2013.08.021.
53. The effect of cdk-5 overexpression on tau phosphorylation and spatial memory of rat. Liao X, etal., Sci China C Life Sci 2004 Jun;47(3):251-7.
54. An exploratory study on STX6, MOBP, MAPT, and EIF2AK3 and late-onset Alzheimer's disease. Liu QY, etal., Neurobiol Aging. 2013 May;34(5):1519.e13-7. doi: 10.1016/j.neurobiolaging.2012.10.004. Epub 2012 Oct 30.
55. N-methyl-D-aspartate receptors mediate epilepsy-induced axonal impairment and tau phosphorylation via activating glycogen synthase kinase-3ß and cyclin-dependent kinase 5. Liu X, etal., Discov Med. 2017 Apr;23(127):221-234.
56. PACSIN1, a Tau-interacting protein, regulates axonal elongation and branching by facilitating microtubule instability. Liu Y, etal., J Biol Chem. 2012 Nov 16;287(47):39911-24. doi: 10.1074/jbc.M112.403451. Epub 2012 Oct 3.
57. Severe diffuse axon injury in chronic alcoholic rat medulla oblongata following a concussion blow. Luo J, etal., Alcohol Alcohol. 2014 May-Jun;49(3):231-7. doi: 10.1093/alcalc/agu009. Epub 2014 Mar 3.
58. Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments. Maas T, etal., J Biol Chem 2000 May 26;275(21):15733-40.
59. Microtubule-dependent oligomerization of tau. Implications for physiological tau function and tauopathies. Makrides V, etal., J Biol Chem 2003 Aug 29;278(35):33298-304. Epub 2003 Jun 12.
60. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
61. The direction of the acceleration and rotational forces associated with mild traumatic brain injury in rodents effect behavioural and molecular outcomes. Mychasiuk R, etal., J Neurosci Methods. 2016 Jan 15;257:168-78. doi: 10.1016/j.jneumeth.2015.10.002. Epub 2015 Oct 17.
62. Synaptic protein alpha1-takusan mitigates amyloid-beta-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites. Nakanishi N, etal., J Neurosci. 2013 Aug 28;33(35):14170-83. doi: 10.1523/JNEUROSCI.4646-10.2013.
63. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
64. AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis. Page G, etal., FEBS Lett 1999 Nov 26;462(1-2):187-91.
65. Hyperphosphorylation of tau protein in hippocampus of central insulin-resistant rats is associated with cognitive impairment. Peng D, etal., Cell Physiol Biochem. 2013;32(5):1417-25. doi: 10.1159/000356579. Epub 2013 Nov 28.
66. Gene expression of estrogen receptor, progesterone receptor and microtubule-associated protein Tau in high-risk early breast cancer: a quest for molecular predictors of treatment benefit in the context of a Hellenic Cooperative Oncology Group trial. Pentheroudakis G, etal., Breast Cancer Res Treat. 2009 Jul;116(1):131-43. doi: 10.1007/s10549-008-0144-9. Epub 2008 Jul 31.
67. Pick's disease is associated with mutations in the tau gene. Pickering-Brown S, etal., Ann Neurol 2000 Dec;48(6):859-67.
68. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
69. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
70. Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration. Pittman AM, etal., J Med Genet. 2005 Nov;42(11):837-46. Epub 2005 Mar 25.
71. Over activation of hippocampal serine/threonine protein phosphatases PP1 and PP2A is involved in lead-induced deficits in learning and memory in young rats. Rahman A, etal., Neurotoxicology. 2012 Jun;33(3):370-83. doi: 10.1016/j.neuro.2012.02.014. Epub 2012 Mar 1.
72. Medical College of Ohio's SSLP Data file transfer Rapp J, Dene H,Direct Electronic Data transfer Feb.(5)2001 . Medical College of Ohio Department of Physiology and Molecular Medicine.
73. GOA pipeline RGD automated data pipeline
74. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
75. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
76. Complete sequence of 3'-untranslated region of Tau from rat central nervous system. Implications for mRNA heterogeneity. Sadot E, etal., J Mol Biol 1994 Aug 12;241(2):325-31.
77. Identification of a tau promoter region mediating tissue-specific-regulated expression in PC12 cells. Sadot E, etal., J Mol Biol 1996 Mar 15;256(5):805-12.
78. The effect of MAPT H1 and APOE epsilon4 on transition from mild cognitive impairment to dementia. Samaranch L, etal., J Alzheimers Dis. 2010;22(4):1065-71. doi: 10.3233/JAD-2010-101011.
79. Molecular diversity at the carboxyl terminus of human and rat tau. Sawa A, etal., Brain Res Mol Brain Res 1994 Nov;27(1):111-7.
80. Stimulation of autophagy is neuroprotective in a mouse model of human tauopathy. Schaeffer V and Goedert M, Autophagy. 2012 Nov;8(11):1686-7. doi: 10.4161/auto.21488. Epub 2012 Aug 9.
81. Hyperphosphorylation and aggregation of tau in experimental autoimmune encephalomyelitis. Schneider A, etal., J Biol Chem 2004 Dec 31;279(53):55833-9. Epub 2004 Oct 19.
82. Downregulation of the microtubule associated protein tau impairs process outgrowth and myelin basic protein mRNA transport in oligodendrocytes. Seiberlich V, etal., Glia. 2015 Sep;63(9):1621-35. doi: 10.1002/glia.22832. Epub 2015 Apr 4.
83. A novel dual GLP-1/GIP receptor agonist alleviates cognitive decline by re-sensitizing insulin signaling in the Alzheimer icv. STZ rat model. Shi L, etal., Behav Brain Res. 2017 Jun 1;327:65-74. doi: 10.1016/j.bbr.2017.03.032. Epub 2017 Mar 23.
84. Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury. Shultz SR, etal., Brain. 2015 May;138(Pt 5):1297-313. doi: 10.1093/brain/awv053. Epub 2015 Mar 13.
85. A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-ß accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload. Sripetchwandee J, etal., Neuroscience. 2016 Sep 22;332:191-202. doi: 10.1016/j.neuroscience.2016.07.003. Epub 2016 Jul 9.
86. Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease. Steinacker P, etal., Sci Rep. 2016 Dec 8;6:38737. doi: 10.1038/srep38737.
87. Passive immunization targeting the N-terminal region of phosphorylated tau (residues 68-71) improves spatial memory in okadaic acid induced tauopathy model rats. Subramanian S, etal., Biochem Biophys Res Commun. 2017 Jan 29;483(1):585-589. doi: 10.1016/j.bbrc.2016.12.101. Epub 2016 Dec 18.
88. The inhibition of Cdk5 activity after hypoxia/ischemia injury reduces infarct size and promotes functional recovery in neonatal rats. Tan X, etal., Neuroscience. 2015 Apr 2;290:552-60. doi: 10.1016/j.neuroscience.2015.01.054. Epub 2015 Feb 7.
89. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
90. Binding of Hsp90 to tau promotes a conformational change and aggregation of tau protein. Tortosa E, etal., J Alzheimers Dis. 2009;17(2):319-25. doi: 10.3233/JAD-2009-1049.
91. Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization. Tortosa E, etal., Neuron. 2017 May 17;94(4):809-825.e7. doi: 10.1016/j.neuron.2017.04.042.
92. Tau-mediated iron export prevents ferroptotic damage after ischemic stroke. Tuo QZ, etal., Mol Psychiatry. 2017 Nov;22(11):1520-1530. doi: 10.1038/mp.2017.171. Epub 2017 Sep 8.
93. Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin. Ubhi K, etal., Acta Neuropathol. 2009 Jun;117(6):699-712. doi: 10.1007/s00401-009-0505-4. Epub 2009 Feb 28.
94. The slow axonal transport of the microtubule-associated protein tau and the transport rates of different isoforms and mutants in cultured neurons. Utton MA, etal., J Neurosci 2002 Aug 1;22(15):6394-400.
95. Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation. van der Harg JM, etal., Neurobiol Dis. 2017 Jul;103:163-173. doi: 10.1016/j.nbd.2017.04.005. Epub 2017 Apr 8.
96. Association of MAPT haplotype-tagging SNPs with sporadic Parkinson's disease. Vandrovcova J, etal., Neurobiol Aging. 2009 Sep;30(9):1477-82. Epub 2007 Dec 26.
97. Vector-mediated expression of erythropoietin improves functional outcome after cervical spinal cord contusion injury. Wang S, etal., Gene Ther. 2012 Sep;19(9):907-14. doi: 10.1038/gt.2011.166. Epub 2011 Nov 3.
98. Transient cerebral ischemia induces site-specific hyperphosphorylation of tau protein. Wen Y, etal., Brain Res. 2004 Oct 1;1022(1-2):30-8.
99. Levodopa/benserazide microsphere (LBM) prevents L-dopa induced dyskinesia by inactivation of the DR1/PKA/P-tau pathway in 6-OHDA-lesioned Parkinson's rats. Xie CL, etal., Sci Rep. 2014 Dec 16;4:7506. doi: 10.1038/srep07506.
100. Overactivation of NR2B-containing NMDA receptors through entorhinal-hippocampal connection initiates accumulation of hyperphosphorylated tau in rat hippocampus after transient middle cerebral artery occlusion. Xu CS, etal., J Neurochem. 2015 Aug;134(3):566-77. doi: 10.1111/jnc.13134. Epub 2015 Jun 4.
101. Human Basic Fibroblast Growth Factor Inhibits Tau Phosphorylation via the PI3K/Akt-GSK3ß Signaling Pathway in a 6-Hydroxydopamine-Induced Model of Parkinson's Disease. Yang PH, etal., Neurodegener Dis. 2016;16(5-6):357-69. doi: 10.1159/000445871. Epub 2016 May 27.
102. Serum- and glucocorticoid-inducible kinase 1 (SGK1) increases neurite formation through microtubule depolymerization by SGK1 and by SGK1 phosphorylation of tau. Yang YC, etal., Mol Cell Biol. 2006 Nov;26(22):8357-70. Epub 2006 Sep 18.
103. Hypoxia-induced tau phosphorylation and memory deficit in rats. Zhang CE, etal., Neurodegener Dis. 2014;14(3):107-16. doi: 10.1159/000362239. Epub 2014 Jun 27.
104. Deficient hippocampal insulin signaling and augmented Tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in Zucker rats. Špolcová A, etal., BMC Neurosci. 2014 Sep 25;15:111. doi: 10.1186/1471-2202-15-111.
Additional References at PubMed
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Genomics

Comparative Map Data
Mapt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81089,638,618 - 89,736,108 (+)NCBIGRCr8
GRCr8 Ensembl1089,638,599 - 89,736,108 (+)EnsemblGRCr8 Ensembl
mRatBN7.21089,138,644 - 89,236,137 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1089,138,627 - 89,236,129 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1094,176,204 - 94,273,767 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01093,639,716 - 93,737,291 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01089,042,500 - 89,139,907 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01092,289,002 - 92,386,517 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1092,288,910 - 92,386,517 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01092,050,754 - 92,147,840 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41093,411,098 - 93,508,762 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1087,832,730 - 87,930,191 (+)NCBICelera
RGSC_v3.11093,425,375 - 93,523,128 (+)NCBI
Cytogenetic Map10q32.1NCBI
MAPT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381745,894,554 - 46,028,334 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1745,894,527 - 46,028,334 (+)EnsemblGRCh38hg38GRCh38
GRCh371743,971,920 - 44,105,700 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361741,327,624 - 41,461,547 (+)NCBINCBI36Build 36hg18NCBI36
Build 341741,327,623 - 41,458,611NCBI
Celera1740,619,037 - 40,753,014 (+)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1739,635,406 - 39,768,427 (+)NCBIHuRef
CHM1_11744,218,591 - 44,352,524 (+)NCBICHM1_1
T2T-CHM13v2.01746,756,177 - 46,889,953 (+)NCBIT2T-CHM13v2.0
Mapt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911104,120,235 - 104,222,916 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11104,122,216 - 104,222,916 (+)EnsemblGRCm39 Ensembl
GRCm3811104,229,409 - 104,332,090 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11104,231,390 - 104,332,090 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711104,092,750 - 104,193,410 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611104,047,526 - 104,148,186 (+)NCBIMGSCv36mm8
Celera11115,951,246 - 116,057,990 (+)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1167.79NCBI
Mapt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547810,225,823 - 10,271,442 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547810,222,439 - 10,271,439 (-)NCBIChiLan1.0ChiLan1.0
MAPT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21918,882,648 - 19,016,175 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11720,851,436 - 20,984,844 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01711,373,220 - 11,506,669 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11711,458,159 - 11,590,626 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1711,458,159 - 11,523,129 (-)Ensemblpanpan1.1panPan2
MAPT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.199,572,174 - 9,674,082 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl99,570,557 - 9,674,349 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha910,679,514 - 10,725,761 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0911,161,388 - 11,263,326 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl911,159,768 - 11,263,320 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1910,175,159 - 10,221,409 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0917,303,033 - 17,349,281 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0917,249,716 - 17,295,984 (+)NCBIUU_Cfam_GSD_1.0
Mapt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560216,714,614 - 16,813,155 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365412,381,411 - 2,479,984 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1217,095,587 - 17,211,373 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11217,098,259 - 17,211,483 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21217,123,502 - 17,234,041 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAPT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11659,894,400 - 60,020,723 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1659,890,221 - 59,955,612 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607730,612,597 - 30,742,938 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mapt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248492,320,887 - 2,421,099 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mapt
872 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:349
Count of miRNA genes:90
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000006856, ENSRNOT00000006947, ENSRNOT00000042984, ENSRNOT00000043604, ENSRNOT00000045127, ENSRNOT00000045134, ENSRNOT00000050070
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105107189796071897Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
8657410Bp374Blood pressure QTL 374heart left ventricle size trait (VT:0002753)heart left ventricle end-diastolic diameter (CMO:0000982)1067476608107713808Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)103550938391417879Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063719161107713808Rat
631555Bp134Blood pressure QTL 1340.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)108101207791729860Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042546145107713808Rat
1549831Bss6Bone structure and strength QTL 64lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)1058073360103073360Rat
12903252Cm113Cardiac mass QTL 1130.047heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
70164Bw21Body weight QTL 214.360.00005body mass (VT:0001259)body weight (CMO:0000012)105429633699451733Rat
4889948Bss91Bone structure and strength QTL 914tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)108306123692869129Rat
1579919Bp281Blood pressure QTL 2810.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105046480295464802Rat
2298548Neuinf7Neuroinflammation QTL 73.4nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1064939013107713808Rat
1302404Cia27Collagen induced arthritis QTL 272.60.0045joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)1076951790107713808Rat
1300107Rf18Renal function QTL 183.41urine output (VT:0003620)timed urine volume (CMO:0000260)1079272424102982300Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104493935989939359Rat
2300218Hpcl2Hepatic cholesterol level QTL 2liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)104552916496099749Rat
70168Eae12Experimental allergic encephalomyelitis QTL 120.0009nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1073599825107713808Rat
70171Cari1Carrageenan-induced inflammation QTL 14.90.0005hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)1054296227107713808Rat
10450495Bp383Blood pressure QTL 3830.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313395464802Rat
12903269Am15Aortic mass QTL 150.042aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
10450493Bp382Blood pressure QTL 3820.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105086028895860288Rat
2313856Bp342Blood pressure QTL 3424.40.0001life span trait (VT:0005372)age at time of death (CMO:0001193)108780775896620484Rat
12903266Cm114Cardiac mass QTL 1140.02heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)1066817119107713808Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2292617Ept18Estrogen-induced pituitary tumorigenesis QTL 183.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107395035396620293Rat
2313103Bss80Bone structure and strength QTL 8020.0001tibia strength trait (VT:1000284)tibia midshaft endosteal cross-sectional area (CMO:0001716)1062556066107556066Rat
12880372Am12Aortic mass QTL 120.003aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1066817119107713808Rat
70193Mcs7Mammary carcinoma susceptibility QTL 72.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
2313105Bss79Bone structure and strength QTL 791.80.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)1062556066107556066Rat
12880375Kidm66Kidney mass QTL 660.009kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
61363Oia3Oil induced arthritis QTL 30.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1087807758107713808Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104493935989939359Rat
1357344Bp249Blood pressure QTL 2490.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)106724133498502431Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
12880370Cm105Cardiac mass QTL 1050.008heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
12880371Cm106Cardiac mass QTL 1060.007heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)1066817119107713808Rat
2306970Anxrr22Anxiety related response QTL 225.95fear/anxiety-related behavior trait (VT:1000241)number of periods of voluntary immobility (CMO:0001045)106184349698710773Rat
11565453Kidm58Kidney mass QTL 580.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1066817119107713808Rat
1359017Hrtrt21Heart rate QTL 212.4heart pumping trait (VT:2000009)heart rate (CMO:0000002)107369533997272278Rat
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1065390777107713808Rat
6893357Bw102Body weight QTL 1020.50.36body mass (VT:0001259)body weight (CMO:0000012)1081012077101828297Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
2306793Ean5Experimental allergic neuritis QTL 54.7nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)107304965694495280Rat
2306792Ean4Experimental allergic neuritis QTL 44nervous system integrity trait (VT:0010566)IFNG-secreting splenocyte count (CMO:0002122)104949549294495492Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1052269185107713808Rat
61396Bp9Blood pressure QTL 94.80.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1068920187107713808Rat
1358915Stresp7Stress response QTL 73.52blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)1065307813107713808Rat
634320Niddm49Non-insulin dependent diabetes mellitus QTL 494.41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1089039175107713808Rat
70363Bp71Blood pressure QTL 710.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1061843496106843496Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
70364Bp72Blood pressure QTL 72arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)108890050196620484Rat
6893366Bw106Body weight QTL 1060.30.47body mass (VT:0001259)body weight (CMO:0000012)1070698731107713808Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
1354608Cm33Cardiac mass QTL 332.8heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)105530797293608131Rat
1558643Cm44Cardiac mass QTL 444.80.0000368heart mass (VT:0007028)heart wet weight (CMO:0000069)1061843496100198886Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040535708107713808Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
7207811Bmd90Bone mineral density QTL 905.2femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)104994371094943710Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040535708107713808Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104493935989939359Rat
1581559Eae18Experimental allergic encephalomyelitis QTL 180.00002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1066108888107555881Rat
6893336Cm75Cardiac mass QTL 750.10.87heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1061843496100198886Rat
631547Bp87Blood pressure QTL 874.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104786912992869129Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
12880055Am11Aortic mass QTL 110.004aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)108450348796432422Rat
2292438Bp311Blood pressure QTL 311arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)107674313395604677Rat
2301398Kidm38Kidney mass QTL 380.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)108450348796432422Rat
2292436Bp310Blood pressure QTL 310arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)105060467795604677Rat
1600367Mcs15Mammary carcinoma susceptibility QTL 154.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1072724423107713808Rat
1358188Ept9Estrogen-induced pituitary tumorigenesis QTL 93.9pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)107395035396620293Rat
631537Oia4Oil induced arthritis QTL 4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1076128947107713808Rat
634354Rends3Renal damage susceptibility QTL 30.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)1061997479106997479Rat
2301405Cm69Cardiac mass QTL 690.031heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)1066817119107713808Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
D10Wox21  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81089,635,822 - 89,635,952 (+)Marker Load Pipeline
mRatBN7.21089,135,845 - 89,135,975 (+)MAPPERmRatBN7.2
Rnor_6.01092,286,199 - 92,286,328NCBIRnor6.0
Rnor_5.01092,047,951 - 92,048,080UniSTSRnor5.0
RGSC_v3.41093,408,294 - 93,408,423UniSTSRGSC3.4
Celera1087,829,949 - 87,830,068UniSTS
Cytogenetic Map10q32.1UniSTS
D10Chm236  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21089,163,076 - 89,163,326 (+)MAPPERmRatBN7.2
Rnor_6.01092,313,428 - 92,313,677NCBIRnor6.0
Rnor_5.01092,075,180 - 92,075,429UniSTSRnor5.0
RGSC_v3.41093,435,526 - 93,435,775UniSTSRGSC3.4
Celera1087,857,142 - 87,857,391UniSTS
Cytogenetic Map10q32.1UniSTS
Mapt  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10q32.1UniSTS
RH127601  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21089,235,748 - 89,235,937 (+)MAPPERmRatBN7.2
Rnor_6.01092,386,129 - 92,386,317NCBIRnor6.0
Rnor_5.01092,147,452 - 92,147,640UniSTSRnor5.0
RGSC_v3.41093,508,374 - 93,508,562UniSTSRGSC3.4
Celera1087,929,803 - 87,929,991UniSTS
RH 3.4 Map10924.29UniSTS
Cytogenetic Map10q32.1UniSTS
RH134050  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21089,148,207 - 89,148,400 (+)MAPPERmRatBN7.2
Rnor_6.01092,298,561 - 92,298,753NCBIRnor6.0
Rnor_5.01092,060,313 - 92,060,505UniSTSRnor5.0
RGSC_v3.41093,420,659 - 93,420,851UniSTSRGSC3.4
Celera1087,842,273 - 87,842,465UniSTS
RH 3.4 Map10917.3UniSTS
Cytogenetic Map10q32.1UniSTS
RH134151  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1087,916,504 - 87,916,712UniSTS
RH 3.4 Map10924.49UniSTS
Cytogenetic Map10q32.1UniSTS
AW532191  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81089,651,280 - 89,651,987 (+)Marker Load Pipeline
mRatBN7.21089,151,304 - 89,152,011 (+)MAPPERmRatBN7.2
Rnor_6.01092,301,658 - 92,302,364NCBIRnor6.0
Rnor_5.01092,063,410 - 92,064,116UniSTSRnor5.0
RGSC_v3.41093,423,756 - 93,424,462UniSTSRGSC3.4
Celera1087,845,372 - 87,846,078UniSTS
RH 3.4 Map10919.9UniSTS
Cytogenetic Map10q32.1UniSTS
BF405908  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21089,218,207 - 89,218,396 (+)MAPPERmRatBN7.2
Rnor_6.01092,368,555 - 92,368,743NCBIRnor6.0
Rnor_5.01092,130,307 - 92,130,495UniSTSRnor5.0
RGSC_v3.41093,490,661 - 93,490,849UniSTSRGSC3.4
Celera1087,912,281 - 87,912,469UniSTS
RH 3.4 Map10925.09UniSTS
Cytogenetic Map10q32.1UniSTS
RH135345  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81089,732,440 - 89,732,643 (+)Marker Load Pipeline
mRatBN7.21089,232,469 - 89,232,672 (+)MAPPERmRatBN7.2
Rnor_6.01092,382,850 - 92,383,052NCBIRnor6.0
Rnor_5.01092,144,168 - 92,144,370UniSTSRnor5.0
RGSC_v3.41093,505,060 - 93,505,262UniSTSRGSC3.4
Celera1087,926,522 - 87,926,726UniSTS
RH 3.4 Map10929.4UniSTS
Cytogenetic Map10q32.1UniSTS
RH138894  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21089,141,732 - 89,141,904 (+)MAPPERmRatBN7.2
Rnor_6.01092,292,087 - 92,292,258NCBIRnor6.0
Rnor_5.01092,053,839 - 92,054,010UniSTSRnor5.0
RGSC_v3.41093,414,183 - 93,414,354UniSTSRGSC3.4
Celera1087,835,815 - 87,835,986UniSTS
RH 3.4 Map10918.59UniSTS
Cytogenetic Map10q32.1UniSTS
G35712  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21089,167,621 - 89,167,884 (+)MAPPERmRatBN7.2
Rnor_6.01092,317,973 - 92,318,235NCBIRnor6.0
Rnor_5.01092,079,725 - 92,079,987UniSTSRnor5.0
RGSC_v3.41093,440,071 - 93,440,333UniSTSRGSC3.4
Celera1087,861,687 - 87,861,949UniSTS
Cytogenetic Map10q32.1UniSTS
UniSTS:224586  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81089,733,374 - 89,733,539 (+)Marker Load Pipeline
mRatBN7.21089,233,403 - 89,233,568 (+)MAPPERmRatBN7.2
Rnor_6.01092,383,784 - 92,383,948NCBIRnor6.0
Rnor_5.01092,145,107 - 92,145,271UniSTSRnor5.0
RGSC_v3.41093,506,029 - 93,506,193UniSTSRGSC3.4
Celera1087,927,458 - 87,927,622UniSTS
Cytogenetic Map10q32.1UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 49 113 91 90 59 25 59 6 218 97 11 93 45 60 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005489770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC126095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG373604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA945776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB556982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB581821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB615367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB726905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB744947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO394225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO394568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO405139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO405815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D30628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D30629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ177309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY311887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M84156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MZ604975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MZ604976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MZ604977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MZ604978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X79321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X94916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000006947   ⟹   ENSRNOP00000006947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,604 - 89,736,100 (+)Ensembl
mRatBN7.2 Ensembl1089,138,627 - 89,236,129 (+)Ensembl
Rnor_6.0 Ensembl1092,288,910 - 92,386,517 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000042984   ⟹   ENSRNOP00000042392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,641 - 89,733,210 (+)Ensembl
mRatBN7.2 Ensembl1089,138,753 - 89,233,239 (+)Ensembl
Rnor_6.0 Ensembl1092,337,879 - 92,382,637 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000045127   ⟹   ENSRNOP00000051451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,610 - 89,732,282 (+)Ensembl
mRatBN7.2 Ensembl1089,138,753 - 89,232,343 (+)Ensembl
Rnor_6.0 Ensembl1092,288,956 - 92,382,691 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000050070   ⟹   ENSRNOP00000040951
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,616 - 89,732,282 (+)Ensembl
mRatBN7.2 Ensembl1089,138,753 - 89,232,343 (+)Ensembl
Rnor_6.0 Ensembl1092,289,107 - 92,382,723 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1089,159,541 - 89,192,808 (+)Ensembl
Rnor_6.0 Ensembl1092,289,055 - 92,343,176 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000092483
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,614 - 89,732,486 (+)Ensembl
mRatBN7.2 Ensembl1089,195,202 - 89,232,311 (+)Ensembl
Rnor_6.0 Ensembl1092,344,292 - 92,364,061 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100910   ⟹   ENSRNOP00000077141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,614 - 89,732,486 (+)Ensembl
mRatBN7.2 Ensembl1089,138,627 - 89,236,129 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111184   ⟹   ENSRNOP00000079242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,619 - 89,732,282 (+)Ensembl
mRatBN7.2 Ensembl1089,138,753 - 89,232,343 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115998   ⟹   ENSRNOP00000097333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,625 - 89,736,108 (+)Ensembl
mRatBN7.2 Ensembl1089,138,666 - 89,236,129 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148055   ⟹   ENSRNOP00000109867
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,599 - 89,732,486 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172649   ⟹   ENSRNOP00000108028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1089,638,641 - 89,732,482 (+)Ensembl
RefSeq Acc Id: NM_017212   ⟹   NP_058908
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,625 - 89,736,108 (+)NCBI
mRatBN7.21089,138,648 - 89,236,137 (+)NCBI
Rnor_6.01092,289,002 - 92,386,517 (+)NCBI
Rnor_5.01092,050,754 - 92,147,840 (+)NCBI
RGSC_v3.41093,411,098 - 93,508,762 (+)RGD
Celera1087,832,730 - 87,930,191 (+)RGD
Sequence:
RefSeq Acc Id: XM_008768268   ⟹   XP_008766490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
Rnor_6.01092,289,042 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768269   ⟹   XP_008766491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
Rnor_6.01092,289,048 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768270   ⟹   XP_008766492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
Rnor_6.01092,289,042 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768272   ⟹   XP_008766494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,232,314 (+)NCBI
Rnor_6.01092,289,042 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768273   ⟹   XP_008766495
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
Rnor_6.01092,289,042 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768277   ⟹   XP_008766499
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,232,257 (+)NCBI
Rnor_6.01092,289,048 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768278   ⟹   XP_008766500
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
Rnor_6.01092,289,002 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768279   ⟹   XP_008766501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
Rnor_6.01092,289,048 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768280   ⟹   XP_008766502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
Rnor_6.01092,289,002 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768281   ⟹   XP_008766503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,232,310 (+)NCBI
Rnor_6.01092,289,002 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008768282   ⟹   XP_008766504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
Rnor_6.01092,289,042 - 92,386,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039085742   ⟹   XP_038941670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085743   ⟹   XP_038941671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085744   ⟹   XP_038941672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085745   ⟹   XP_038941673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085746   ⟹   XP_038941674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085747   ⟹   XP_038941675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085748   ⟹   XP_038941676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085749   ⟹   XP_038941677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085750   ⟹   XP_038941678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085751   ⟹   XP_038941679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085752   ⟹   XP_038941680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085753   ⟹   XP_038941681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085754   ⟹   XP_038941682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085755   ⟹   XP_038941683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085763   ⟹   XP_038941691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_039085764   ⟹   XP_038941692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
mRatBN7.21089,138,644 - 89,236,132 (+)NCBI
RefSeq Acc Id: XM_063268818   ⟹   XP_063124888
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268819   ⟹   XP_063124889
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268820   ⟹   XP_063124890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268821   ⟹   XP_063124891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268822   ⟹   XP_063124892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268823   ⟹   XP_063124893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268824   ⟹   XP_063124894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268825   ⟹   XP_063124895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268826   ⟹   XP_063124896
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268827   ⟹   XP_063124897
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268828   ⟹   XP_063124898
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XM_063268829   ⟹   XP_063124899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,736,108 (+)NCBI
RefSeq Acc Id: XR_005489770
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81089,638,618 - 89,710,282 (+)NCBI
mRatBN7.21089,138,644 - 89,210,310 (+)NCBI
Protein Sequences
Protein RefSeqs NP_058908 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766490 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766491 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766492 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766494 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766495 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766499 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766500 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766501 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766502 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766503 (Get FASTA)   NCBI Sequence Viewer  
  XP_008766504 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941670 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941671 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941672 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941673 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941674 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941675 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941676 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941677 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941678 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941679 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941680 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941681 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941682 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941683 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941691 (Get FASTA)   NCBI Sequence Viewer  
  XP_038941692 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124888 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124889 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124890 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124891 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124892 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124893 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124894 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124895 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124896 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124897 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124898 (Get FASTA)   NCBI Sequence Viewer  
  XP_063124899 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA42204 (Get FASTA)   NCBI Sequence Viewer  
  AAI26096 (Get FASTA)   NCBI Sequence Viewer  
  ABA02201 (Get FASTA)   NCBI Sequence Viewer  
  CAA55889 (Get FASTA)   NCBI Sequence Viewer  
  EDM06297 (Get FASTA)   NCBI Sequence Viewer  
  EDM06298 (Get FASTA)   NCBI Sequence Viewer  
  EDM06299 (Get FASTA)   NCBI Sequence Viewer  
  EDM06300 (Get FASTA)   NCBI Sequence Viewer  
  EDM06301 (Get FASTA)   NCBI Sequence Viewer  
  EDM06302 (Get FASTA)   NCBI Sequence Viewer  
  EDM06303 (Get FASTA)   NCBI Sequence Viewer  
  EDM06304 (Get FASTA)   NCBI Sequence Viewer  
  EDM06305 (Get FASTA)   NCBI Sequence Viewer  
  EDM06306 (Get FASTA)   NCBI Sequence Viewer  
  EDM06307 (Get FASTA)   NCBI Sequence Viewer  
  EDM06308 (Get FASTA)   NCBI Sequence Viewer  
  EDM06309 (Get FASTA)   NCBI Sequence Viewer  
  EDM06310 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006947
  ENSRNOP00000040951
  ENSRNOP00000051451
  ENSRNOP00000077141
  ENSRNOP00000079242
  ENSRNOP00000091569
  ENSRNOP00000097333
  ENSRNOP00000108028
  ENSRNOP00000109867
GenBank Protein P19332 (Get FASTA)   NCBI Sequence Viewer  
  UGN13705 (Get FASTA)   NCBI Sequence Viewer  
  UGN13706 (Get FASTA)   NCBI Sequence Viewer  
  UGN13707 (Get FASTA)   NCBI Sequence Viewer  
  UGN13708 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_058908   ⟸   NM_017212
- UniProtKB: A0A8K1TN53 (UniProtKB/TrEMBL),   A6HJV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766504   ⟸   XM_008768282
- Peptide Label: isoform X1
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766492   ⟸   XM_008768270
- Peptide Label: isoform X5
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766490   ⟸   XM_008768268
- Peptide Label: isoform X2
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot),   A0A8I5ZN17 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766491   ⟸   XM_008768269
- Peptide Label: isoform X37
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766494   ⟸   XM_008768272
- Peptide Label: isoform X8
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot),   A0A8K1WHA3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766495   ⟸   XM_008768273
- Peptide Label: isoform X10
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008766501   ⟸   XM_008768279
- Peptide Label: isoform X26
- UniProtKB: A0A8J8XUY4 (UniProtKB/TrEMBL),   A6HJU3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766499   ⟸   XM_008768277
- Peptide Label: isoform X22
- UniProtKB: A0A8K1WG57 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766500   ⟸   XM_008768278
- Peptide Label: isoform X25
- UniProtKB: A0A8K1TMD4 (UniProtKB/TrEMBL),   A6HJV2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766502   ⟸   XM_008768280
- Peptide Label: isoform X30
- UniProtKB: A6HJU3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766503   ⟸   XM_008768281
- Peptide Label: isoform X35
- UniProtKB: A0JN25 (UniProtKB/TrEMBL),   E9PT48 (UniProtKB/TrEMBL),   A6HJU3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000051451   ⟸   ENSRNOT00000045127
Ensembl Acc Id: ENSRNOP00000006947   ⟸   ENSRNOT00000006947
Ensembl Acc Id: ENSRNOP00000042392   ⟸   ENSRNOT00000042984
Ensembl Acc Id: ENSRNOP00000040951   ⟸   ENSRNOT00000050070
RefSeq Acc Id: XP_038941671   ⟸   XM_039085743
- Peptide Label: isoform X4
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038941673   ⟸   XM_039085745
- Peptide Label: isoform X7
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038941674   ⟸   XM_039085746
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038941678   ⟸   XM_039085750
- Peptide Label: isoform X19
RefSeq Acc Id: XP_038941670   ⟸   XM_039085742
- Peptide Label: isoform X3
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038941692   ⟸   XM_039085764
- Peptide Label: isoform X39
- UniProtKB: A6HJU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941675   ⟸   XM_039085747
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038941680   ⟸   XM_039085752
- Peptide Label: isoform X23
- UniProtKB: A6HJU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941676   ⟸   XM_039085748
- Peptide Label: isoform X17
RefSeq Acc Id: XP_038941681   ⟸   XM_039085753
- Peptide Label: isoform X27
RefSeq Acc Id: XP_038941672   ⟸   XM_039085744
- Peptide Label: isoform X6
- UniProtKB: Q9QW06 (UniProtKB/Swiss-Prot),   Q63677 (UniProtKB/Swiss-Prot),   Q63567 (UniProtKB/Swiss-Prot),   P19332 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038941677   ⟸   XM_039085749
- Peptide Label: isoform X18
RefSeq Acc Id: XP_038941682   ⟸   XM_039085754
- Peptide Label: isoform X28
- UniProtKB: D3ZKD9 (UniProtKB/TrEMBL),   A6HJV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941679   ⟸   XM_039085751
- Peptide Label: isoform X21
RefSeq Acc Id: XP_038941683   ⟸   XM_039085755
- Peptide Label: isoform X31
- UniProtKB: A6HJV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941691   ⟸   XM_039085763
- Peptide Label: isoform X33
- UniProtKB: A0A8I6ARL1 (UniProtKB/TrEMBL),   A6HJV2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000097333   ⟸   ENSRNOT00000115998
Ensembl Acc Id: ENSRNOP00000079242   ⟸   ENSRNOT00000111184
Ensembl Acc Id: ENSRNOP00000077141   ⟸   ENSRNOT00000100910
RefSeq Acc Id: XP_063124891   ⟸   XM_063268821
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063124899   ⟸   XM_063268829
- Peptide Label: isoform X38
- UniProtKB: A6HJV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124888   ⟸   XM_063268818
- Peptide Label: isoform X9
- UniProtKB: D4A1Q2 (UniProtKB/TrEMBL),   A6HJV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124892   ⟸   XM_063268822
- Peptide Label: isoform X16
RefSeq Acc Id: XP_063124895   ⟸   XM_063268825
- Peptide Label: isoform X29
- UniProtKB: A6HJV2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124897   ⟸   XM_063268827
- Peptide Label: isoform X34
- UniProtKB: A6HJU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124889   ⟸   XM_063268819
- Peptide Label: isoform X11
- UniProtKB: A0A8I5YBN3 (UniProtKB/TrEMBL),   A6HJV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124890   ⟸   XM_063268820
- Peptide Label: isoform X12
- UniProtKB: A6HJU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124893   ⟸   XM_063268823
- Peptide Label: isoform X20
RefSeq Acc Id: XP_063124894   ⟸   XM_063268824
- Peptide Label: isoform X24
- UniProtKB: A6HJU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124896   ⟸   XM_063268826
- Peptide Label: isoform X32
- UniProtKB: A6HJU3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063124898   ⟸   XM_063268828
- Peptide Label: isoform X36
- UniProtKB: A6HJV4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000109867   ⟸   ENSRNOT00000148055
Ensembl Acc Id: ENSRNOP00000108028   ⟸   ENSRNOT00000172649

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P19332-F1-model_v2 AlphaFold P19332 1-752 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697820
Promoter ID:EPDNEW_R8344
Type:multiple initiation site
Name:Mapt_1
Description:microtubule-associated protein tau
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01092,288,999 - 92,289,059EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69329 AgrOrtholog
BioCyc Gene G2FUF-23021 BioCyc
Ensembl Genes ENSRNOG00000005133 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000006947 ENTREZGENE
  ENSRNOT00000045127 ENTREZGENE
  ENSRNOT00000050070 ENTREZGENE
  ENSRNOT00000092483 ENTREZGENE
  ENSRNOT00000100910 ENTREZGENE
  ENSRNOT00000111184 ENTREZGENE
  ENSRNOT00000115998 ENTREZGENE
  ENSRNOT00000148055 ENTREZGENE
  ENSRNOT00000172649 ENTREZGENE
IMAGE_CLONE IMAGE:8367931 IMAGE-MGC_LOAD
InterPro MAP2/MAP4/Tau UniProtKB/Swiss-Prot
  MAP_tubulin-bd_rpt UniProtKB/Swiss-Prot
  Tau UniProtKB/Swiss-Prot
MGC_CLONE MGC:156663 IMAGE-MGC_LOAD
NCBI Gene 29477 ENTREZGENE
PANTHER MICROTUBULE-ASSOCIATED PROTEIN UniProtKB/Swiss-Prot
  MICROTUBULE-ASSOCIATED PROTEIN TAU UniProtKB/Swiss-Prot
Pfam Tubulin-binding UniProtKB/Swiss-Prot
PharmGKB MAPT RGD
PhenoGen Mapt PhenoGen
PRINTS TAUPROTEIN UniProtKB/Swiss-Prot
PROSITE TAU_MAP_1 UniProtKB/Swiss-Prot
  TAU_MAP_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000005133 RatGTEx
TIGR TC216545
UniProt A0A8I5YBN3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZN00_RAT UniProtKB/TrEMBL
  A0A8I5ZN17 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ABX0_RAT UniProtKB/TrEMBL
  A0A8I6ARL1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8XUY4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8K1TMD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8K1TN53 ENTREZGENE, UniProtKB/TrEMBL
  A0A8K1WG57 ENTREZGENE, UniProtKB/TrEMBL
  A0A8K1WHA3 ENTREZGENE, UniProtKB/TrEMBL
  A0JN25 ENTREZGENE, UniProtKB/TrEMBL
  A6HJU3 ENTREZGENE, UniProtKB/TrEMBL
  A6HJU8 ENTREZGENE, UniProtKB/TrEMBL
  A6HJV0 ENTREZGENE, UniProtKB/TrEMBL
  A6HJV2 ENTREZGENE, UniProtKB/TrEMBL
  A6HJV4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZKD9 ENTREZGENE, UniProtKB/TrEMBL
  D4A1Q2 ENTREZGENE, UniProtKB/TrEMBL
  E9PT48 ENTREZGENE
  F1LST4_RAT UniProtKB/TrEMBL
  P19332 ENTREZGENE
  Q63567 ENTREZGENE
  Q63677 ENTREZGENE
  Q9QW06 ENTREZGENE
  TAU_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q63567 UniProtKB/Swiss-Prot
  Q63677 UniProtKB/Swiss-Prot
  Q9QW06 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Mapt  microtubule-associated protein tau      Symbol and Name updated 629477 APPROVED
2003-03-12 Mapt  microtubule-associated protein tau  Mtapt  microtubule-associated protein tau  Data merged from RGD:3121 628472 PROVISIONAL
2002-06-10 Mtapt  Tau microtubule-associated protein,      Symbol and Name status set to approved 70586 APPROVED
2002-06-10 Mapt  microtubule-associated protein tau      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_transcript expected size is 229 bp 68814
gene_transcript promoter is G + C-rich, lacks a genuine TATA box and can promote multiple initiation sites for RNA transcription 729193