Litaf (lipopolysaccharide-induced TNF factor) - Rat Genome Database

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Gene: Litaf (lipopolysaccharide-induced TNF factor) Rattus norvegicus
Analyze
Symbol: Litaf
Name: lipopolysaccharide-induced TNF factor
RGD ID: 69294
Description: Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; WW domain binding activity; and zinc ion binding activity. Predicted to be involved in positive regulation of canonical NF-kappaB signal transduction; positive regulation of transcription by RNA polymerase II; and regulation of cytokine production. Predicted to act upstream of or within cellular response to lipopolysaccharide; negative regulation of non-canonical NF-kappaB signal transduction; and regulation of macrophage cytokine production. Predicted to be located in several cellular components, including Golgi apparatus; bounding membrane of organelle; and cytoplasmic side of plasma membrane. Predicted to be active in cytoplasmic side of late endosome membrane; cytoplasmic side of lysosomal membrane; and nucleus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1C. Orthologous to human LITAF (lipopolysaccharide induced TNF factor); INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EET-1; estrogen-enhanced transcript protein 1; estrogen-responsive uterine transcript; lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; LPS-induced TN factor; LPS-induced TNF-alpha factor; LPS-induced TNF-alpha factor homolog; Pig7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8105,163,258 - 5,199,930 (+)NCBIGRCr8
mRatBN7.2104,656,308 - 4,692,981 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl104,625,552 - 4,692,763 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx109,352,930 - 9,389,597 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0108,874,034 - 8,910,699 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0104,512,289 - 4,548,952 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0104,753,546 - 4,763,272 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl104,719,713 - 4,763,510 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0103,580,243 - 3,589,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4104,614,177 - 4,623,903 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1104,587,486 - 4,623,903 (+)NCBI
Celera103,704,946 - 3,714,672 (+)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3,5-trinitro-1,3,5-triazinane  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
azoxystrobin  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
butan-1-ol  (ISO)
cadmium dichloride  (EXP)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
cobalt dichloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (EXP)
dioxygen  (EXP,ISO)
dopamine  (EXP)
dorsomorphin  (ISO)
elemental selenium  (ISO)
ellagic acid  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (ISO)
fenoldopam  (EXP)
fenthion  (ISO)
finasteride  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fumonisin B1  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
imidacloprid  (EXP)
indometacin  (ISO)
inulin  (ISO)
isobutanol  (ISO)
isoprenaline  (ISO)
lipopolysaccharide  (ISO)
Mecamylamine  (ISO)
mercury dichloride  (EXP)
methimazole  (EXP)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
morphine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
nicotine  (ISO)
nicotinic acid  (EXP)
oxaliplatin  (EXP)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phosgene  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
poly(ethylene)  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
sarin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
simvastatin  (EXP)
sodium arsenite  (ISO)
Soman  (EXP)
streptozocin  (EXP)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sulindac  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thiabendazole  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium atom  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tubocurarine  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome. Bixler GV, etal., BMC Med Genomics. 2011 May 15;4:40. doi: 10.1186/1755-8794-4-40.
2. A novel estrogen-enhanced transcript identified in the rat uterus by differential display. Everett LM, etal., Endocrinology 1997 Sep;138(9):3836-41.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Regulation of brain cell environment on neuronal protection: role of TNFalpha in glia cells. Hamano H, etal., Life Sci 2002 Dec 20;72(4-5):565-74.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Age-related alterations in retinal neurovascular and inflammatory transcripts. Van Kirk CA, etal., Mol Vis. 2011;17:1261-74. Epub 2011 May 7.
Additional References at PubMed
PMID:11274176   PMID:12477932   PMID:12655064   PMID:12761501   PMID:12914755   PMID:15064722   PMID:16118794   PMID:16954198   PMID:21217782   PMID:22160695   PMID:27582497  


Genomics

Comparative Map Data
Litaf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8105,163,258 - 5,199,930 (+)NCBIGRCr8
mRatBN7.2104,656,308 - 4,692,981 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl104,625,552 - 4,692,763 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx109,352,930 - 9,389,597 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0108,874,034 - 8,910,699 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0104,512,289 - 4,548,952 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0104,753,546 - 4,763,272 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl104,719,713 - 4,763,510 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0103,580,243 - 3,589,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4104,614,177 - 4,623,903 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1104,587,486 - 4,623,903 (+)NCBI
Celera103,704,946 - 3,714,672 (+)NCBICelera
Cytogenetic Map10q11NCBI
LITAF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381611,547,722 - 11,640,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1611,546,875 - 11,636,381 (-)EnsemblGRCh38hg38GRCh38
GRCh371611,641,578 - 11,681,322 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361611,549,357 - 11,587,730 (-)NCBINCBI36Build 36hg18NCBI36
Build 341611,549,957 - 11,587,730NCBI
Celera1611,813,516 - 11,854,903 (-)NCBICelera
Cytogenetic Map16p13.13NCBI
HuRef1611,558,982 - 11,598,664 (-)NCBIHuRef
CHM1_11611,641,642 - 11,681,379 (-)NCBICHM1_1
T2T-CHM13v2.01611,583,827 - 11,676,644 (-)NCBIT2T-CHM13v2.0
Litaf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391610,777,137 - 10,810,985 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1610,777,139 - 10,884,021 (-)EnsemblGRCm39 Ensembl
GRCm381610,959,273 - 10,993,121 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1610,959,275 - 11,066,157 (-)EnsemblGRCm38mm10GRCm38
MGSCv371610,959,366 - 10,993,214 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361610,872,852 - 10,880,228 (-)NCBIMGSCv36mm8
Celera1611,588,622 - 11,622,564 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map166.28NCBI
Litaf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554427,077,823 - 7,083,437 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554427,054,418 - 7,084,973 (+)NCBIChiLan1.0ChiLan1.0
LITAF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21812,096,353 - 12,135,778 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11615,866,852 - 15,905,996 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01610,488,738 - 10,527,843 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11611,714,325 - 11,753,902 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1611,714,325 - 11,750,521 (-)Ensemblpanpan1.1panPan2
LITAF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1631,229,153 - 31,259,670 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha632,609,055 - 32,637,581 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0631,407,890 - 31,436,572 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl631,407,820 - 31,438,525 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1631,221,767 - 31,250,391 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0631,095,973 - 31,124,591 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0631,519,895 - 31,548,477 (+)NCBIUU_Cfam_GSD_1.0
Litaf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344111,563,943 - 111,567,545 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365309,409,692 - 9,421,974 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365309,409,378 - 9,421,974 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LITAF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl331,482,353 - 31,579,082 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1331,482,605 - 31,576,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2332,319,463 - 32,363,158 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LITAF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1511,023,158 - 11,099,133 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl511,021,717 - 11,059,149 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606819,054,852 - 19,135,028 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Litaf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247826,720,497 - 6,747,317 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247826,715,584 - 6,748,873 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Litaf
301 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:195
Count of miRNA genes:134
Interacting mature miRNAs:167
Transcripts:ENSRNOT00000003412
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129497586Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1549898Neuinf3Neuroinflammation QTL 326.4nervous system integrity trait (VT:0010566)MHC Class II RT1A-positive spinal cord ventral horn area to total spinal cord ventral horn area ratio (CMO:0001980)1034063205387112Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000003412   ⟹   ENSRNOP00000003412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl104,656,338 - 4,692,763 (+)Ensembl
Rnor_6.0 Ensembl104,719,713 - 4,763,510 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108567   ⟹   ENSRNOP00000085735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl104,625,552 - 4,692,735 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119324   ⟹   ENSRNOP00000080863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl104,682,074 - 4,692,741 (+)Ensembl
RefSeq Acc Id: NM_001105735   ⟹   NP_001099205
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8105,163,258 - 5,199,930 (+)NCBI
mRatBN7.2104,656,308 - 4,692,981 (+)NCBI
Rnor_6.0104,753,546 - 4,763,272 (+)NCBI
Rnor_5.0103,580,243 - 3,589,969 (+)NCBI
RGSC_v3.4104,614,177 - 4,623,903 (+)RGD
Celera103,704,946 - 3,714,672 (+)RGD
Sequence:
RefSeq Acc Id: XM_039086806   ⟹   XP_038942734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8105,182,075 - 5,199,719 (+)NCBI
mRatBN7.2104,675,124 - 4,692,981 (+)NCBI
RefSeq Acc Id: XM_063269825   ⟹   XP_063125895
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8105,173,878 - 5,199,719 (+)NCBI
RefSeq Acc Id: NP_001099205   ⟸   NM_001105735
- UniProtKB: P0C0T0 (UniProtKB/Swiss-Prot),   A0A8L2Q1K5 (UniProtKB/TrEMBL),   B2RYP2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003412   ⟸   ENSRNOT00000003412
RefSeq Acc Id: XP_038942734   ⟸   XM_039086806
- Peptide Label: isoform X1
- UniProtKB: P0C0T0 (UniProtKB/Swiss-Prot),   A0A8L2Q1K5 (UniProtKB/TrEMBL),   B2RYP2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000085735   ⟸   ENSRNOT00000108567
Ensembl Acc Id: ENSRNOP00000080863   ⟸   ENSRNOT00000119324
RefSeq Acc Id: XP_063125895   ⟸   XM_063269825
- Peptide Label: isoform X1
- UniProtKB: P0C0T0 (UniProtKB/Swiss-Prot),   B2RYP2 (UniProtKB/TrEMBL)
Protein Domains
LITAF

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P0C0T0-F1-model_v2 AlphaFold P0C0T0 1-161 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69294 AgrOrtholog
BioCyc Gene G2FUF-26152 BioCyc
Ensembl Genes ENSRNOG00000002520 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055018573 UniProtKB/Swiss-Prot
  ENSRNOG00060012774 UniProtKB/Swiss-Prot
  ENSRNOG00065002811 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000003412.4 UniProtKB/TrEMBL
  ENSRNOT00000108567.1 UniProtKB/Swiss-Prot
  ENSRNOT00000119324.1 UniProtKB/TrEMBL
  ENSRNOT00055031602 UniProtKB/Swiss-Prot
  ENSRNOT00060021714 UniProtKB/Swiss-Prot
  ENSRNOT00065003862 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:9091522 IMAGE-MGC_LOAD
InterPro LITAF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LITAF_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:65161 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:188754 IMAGE-MGC_LOAD
NCBI Gene Litaf ENTREZGENE
PANTHER LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR23292 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam zf-LITAF-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Litaf PhenoGen
PROSITE LITAF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002520 RatGTEx
  ENSRNOG00055018573 RatGTEx
  ENSRNOG00060012774 RatGTEx
  ENSRNOG00065002811 RatGTEx
SMART LITAF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZRT4_RAT UniProtKB/TrEMBL
  A0A8L2Q1K5 ENTREZGENE, UniProtKB/TrEMBL
  B2RYP2 ENTREZGENE, UniProtKB/TrEMBL
  LITAF_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Litaf  lipopolysaccharide-induced TNF factor  Litaf  LPS-induced TN factor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Litaf  LPS-induced TN factor    LPS-induced TNF-alpha factor  Name updated 1299863 APPROVED
2004-08-25 Litaf  LPS-induced TNF-alpha factor  Pig7  LPS-induced TNF-alpha factor  Data merged from RGD:620422 737654 PROVISIONAL
2002-08-07 Pig7  LPS-induced TNF-alpha factor      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Litaf  LPS-induced TNF-alpha factor      Name updated 70584 APPROVED
2002-02-20 Litaf  LPS-induced TNF-alpha factor      Symbol updated to reflect Human and Mouse nomenclature 70282 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_regulation expression is responsive to estrogen only in tissues of the reproductive tract and in the kidney 68813