Fetub (fetuin B) - Rat Genome Database

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Gene: Fetub (fetuin B) Rattus norvegicus
Analyze
Symbol: Fetub
Name: fetuin B
RGD ID: 69293
Description: Predicted to enable metalloendopeptidase inhibitor activity. Predicted to be involved in binding activity of sperm to zona pellucida and negative regulation of endopeptidase activity. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Orthologous to human FETUB (fetuin B); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fet; Fet_mapped; Fetuin (phosphoprotein, 63 kDa); fetuin beta; fetuin phosphoprotein; fetuin phosphoprotein (mapped); fetuin-B; fetuin-like protein IRL685; IRL685; Pp63
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,586,750 - 91,599,789 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1191,586,748 - 91,599,310 (-)EnsemblGRCr8
mRatBN7.21178,082,158 - 78,093,022 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1178,082,156 - 78,095,135 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1186,832,633 - 86,843,497 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,490,850 - 79,501,599 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,546,941 - 78,557,807 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01181,648,890 - 81,660,472 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,648,885 - 81,660,395 (-)Ensemblrn6Rnor6.0
Rnor_5.01184,745,605 - 84,758,630 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41180,276,852 - 80,285,039 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1176,955,006 - 76,965,868 (-)NCBICelera
RGSC_v3.11180,334,442 - 80,342,628 (-)NCBI
Cytogenetic Map11q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (ISO)
chlorpromazine  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
dichloroacetic acid  (ISO)
dioxygen  (EXP)
doxorubicin  (EXP)
fenthion  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
genistein  (EXP,ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
isoprenaline  (ISO)
methapyrilene  (EXP)
methyltestosterone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N(4)-hydroxycytidine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
naphthalene  (ISO)
nickel sulfate  (ISO)
nitrofen  (EXP)
O-methyleugenol  (ISO)
obeticholic acid  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
rac-lactic acid  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
trichloroethene  (EXP)
triclosan  (ISO)
Triptolide  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vitamin D  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Fetuin-B, a second member of the fetuin family in mammals. Olivier E, etal., Biochem J 2000 Sep 1;350 Pt 2:589-97.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:1300185   PMID:12676929   PMID:23533145   PMID:23562279   PMID:37364770  


Genomics

Comparative Map Data
Fetub
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,586,750 - 91,599,789 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1191,586,748 - 91,599,310 (-)EnsemblGRCr8
mRatBN7.21178,082,158 - 78,093,022 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1178,082,156 - 78,095,135 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1186,832,633 - 86,843,497 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,490,850 - 79,501,599 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,546,941 - 78,557,807 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01181,648,890 - 81,660,472 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1181,648,885 - 81,660,395 (-)Ensemblrn6Rnor6.0
Rnor_5.01184,745,605 - 84,758,630 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41180,276,852 - 80,285,039 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1176,955,006 - 76,965,868 (-)NCBICelera
RGSC_v3.11180,334,442 - 80,342,628 (-)NCBI
Cytogenetic Map11q23NCBI
FETUB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,635,969 - 186,653,141 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3186,635,969 - 186,653,141 (+)Ensemblhg38GRCh38
GRCh373186,353,758 - 186,370,930 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,840,843 - 187,853,491 (+)NCBIBuild 36Build 36hg18NCBI36
Build 343187,840,850 - 187,853,498NCBI
Celera3184,794,517 - 184,807,165 (+)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3183,767,693 - 183,780,343 (+)NCBIHuRef
CHM1_13186,322,116 - 186,334,762 (+)NCBICHM1_1
T2T-CHM13v2.03189,451,683 - 189,468,852 (+)NCBIT2T-CHM13v2.0
Fetub
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,737,132 - 22,758,518 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1622,737,084 - 22,758,528 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381622,918,382 - 22,939,768 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1622,918,334 - 22,939,778 (+)Ensemblmm10GRCm38
MGSCv371622,918,455 - 22,939,841 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361622,835,635 - 22,855,086 (+)NCBIMGSCv36mm8
Celera1623,478,707 - 23,499,723 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.76NCBI
Fetub
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542021,040,621 - 21,054,391 (-)Ensembl
ChiLan1.0NW_00495542021,041,419 - 21,054,043 (-)NCBIChiLan1.0ChiLan1.0
FETUB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22184,511,004 - 184,528,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13184,515,719 - 184,533,652 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03183,675,258 - 183,687,754 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13192,142,595 - 192,155,297 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,142,702 - 192,154,920 (+)EnsemblpanPan2panpan1.1
FETUB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,259,362 - 19,273,030 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,259,357 - 19,273,030 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3423,344,736 - 23,358,404 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03419,170,300 - 19,183,973 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3419,170,391 - 19,213,757 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13419,202,641 - 19,216,289 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03419,202,473 - 19,216,130 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03419,430,947 - 19,444,615 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fetub
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,210,109 - 117,225,168 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365783,302,084 - 3,310,536 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365783,302,005 - 3,310,536 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FETUB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,460,272 - 124,494,196 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113124,480,456 - 124,494,197 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213133,870,414 - 133,884,133 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FETUB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1152,773,057 - 2,790,944 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl152,770,927 - 2,790,248 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606311,509,843 - 11,526,819 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fetub
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473070,090,385 - 70,107,199 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473070,092,056 - 70,112,025 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Fetub
25 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:193
Count of miRNA genes:105
Interacting mature miRNAs:110
Transcripts:ENSRNOT00000046199, ENSRNOT00000048739
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat

Markers in Region
RH134374  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21178,082,203 - 78,082,406 (+)MAPPERmRatBN7.2
Rnor_6.01181,648,936 - 81,649,138NCBIRnor6.0
Rnor_5.01184,745,651 - 84,745,853UniSTSRnor5.0
RGSC_v3.41180,276,898 - 80,277,100UniSTSRGSC3.4
Celera1176,955,052 - 76,955,254UniSTS
RH 3.4 Map11649.9UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 10 26 92 91 90 59 70 59 6 286 127 11 63 79 87 31 6 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001309522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ242926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MW395163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000048739   ⟹   ENSRNOP00000051504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1191,586,767 - 91,597,612 (-)Ensembl
mRatBN7.2 Ensembl1178,082,175 - 78,093,022 (-)Ensembl
Rnor_6.0 Ensembl1181,648,885 - 81,660,395 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100999   ⟹   ENSRNOP00000082888
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1191,586,748 - 91,595,402 (-)Ensembl
mRatBN7.2 Ensembl1178,082,156 - 78,090,810 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114827   ⟹   ENSRNOP00000097728
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1191,586,748 - 91,599,310 (-)Ensembl
mRatBN7.2 Ensembl1178,082,156 - 78,095,135 (-)Ensembl
RefSeq Acc Id: NM_001309522   ⟹   NP_001296451
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81191,586,766 - 91,597,612 (-)NCBI
mRatBN7.21178,082,174 - 78,093,022 (-)NCBI
Rnor_6.01181,648,906 - 81,660,472 (-)NCBI
Celera1176,955,022 - 76,965,868 (-)NCBI
Sequence:
RefSeq Acc Id: NM_053348   ⟹   NP_445800
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81191,586,750 - 91,594,972 (-)NCBI
mRatBN7.21178,082,158 - 78,090,380 (-)NCBI
Rnor_6.01181,648,890 - 81,657,471 (-)NCBI
Rnor_5.01184,745,605 - 84,758,630 (-)NCBI
RGSC_v3.41180,276,852 - 80,285,039 (-)RGD
Celera1176,955,006 - 76,963,228 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063270776   ⟹   XP_063126846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81191,586,750 - 91,599,789 (-)NCBI
RefSeq Acc Id: XM_063270777   ⟹   XP_063126847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81191,586,750 - 91,599,011 (-)NCBI
RefSeq Acc Id: NP_445800   ⟸   NM_053348
- Peptide Label: precursor
- UniProtKB: F1LN83 (UniProtKB/Swiss-Prot),   Q9QX79 (UniProtKB/Swiss-Prot),   A0A8I5ZW28 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001296451   ⟸   NM_001309522
- Peptide Label: isoform 1 precursor
- UniProtKB: Q6IRS6 (UniProtKB/TrEMBL),   A6JS44 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000051504   ⟸   ENSRNOT00000048739
Ensembl Acc Id: ENSRNOP00000097728   ⟸   ENSRNOT00000114827
Ensembl Acc Id: ENSRNOP00000082888   ⟸   ENSRNOT00000100999
RefSeq Acc Id: XP_063126846   ⟸   XM_063270776
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AWQ8 (UniProtKB/TrEMBL),   A0A8I5ZW28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126847   ⟸   XM_063270777
- Peptide Label: isoform X2
- UniProtKB: A6JS45 (UniProtKB/TrEMBL),   A0A8I5ZW28 (UniProtKB/TrEMBL)
Protein Domains
Cystatin fetuin-B-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QX79-F1-model_v2 AlphaFold Q9QX79 1-378 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698249
Promoter ID:EPDNEW_R8774
Type:initiation region
Name:Fetub_1
Description:fetuin B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01181,660,207 - 81,660,267EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69293 AgrOrtholog
BioCyc Gene G2FUF-20830 BioCyc
Ensembl Genes ENSRNOG00000001806 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000048739 ENTREZGENE
  ENSRNOT00000100999 ENTREZGENE
  ENSRNOT00000114827 ENTREZGENE
Gene3D-CATH 3.10.450.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7099154 IMAGE-MGC_LOAD
InterPro Cystatin_dom UniProtKB/Swiss-Prot
  Cystatin_Fetuin_B UniProtKB/Swiss-Prot
  Cystatin_sf UniProtKB/Swiss-Prot
  Kininogen_Fetuin_HRG UniProtKB/Swiss-Prot
  Prot_inh_fetuin_CS UniProtKB/Swiss-Prot
KEGG Report rno:83928 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91528 IMAGE-MGC_LOAD
NCBI Gene 83928 ENTREZGENE
PANTHER FETUIN UniProtKB/Swiss-Prot
  FETUIN-B UniProtKB/Swiss-Prot
Pfam Cystatin UniProtKB/Swiss-Prot
PhenoGen Fetub PhenoGen
PROSITE CYSTATIN_FETUIN_B UniProtKB/Swiss-Prot
  FETUIN_1 UniProtKB/Swiss-Prot
  FETUIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001806 RatGTEx
SMART SM00043 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54403 UniProtKB/Swiss-Prot
TIGR TC218955
UniProt A0A8A1UFB2_RAT UniProtKB/TrEMBL
  A0A8I5ZW28 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AWQ8 ENTREZGENE, UniProtKB/TrEMBL
  A6JS44 ENTREZGENE, UniProtKB/TrEMBL
  A6JS45 ENTREZGENE, UniProtKB/TrEMBL
  F1LN83 ENTREZGENE
  FETUB_RAT UniProtKB/Swiss-Prot
  Q6IRS6 ENTREZGENE, UniProtKB/TrEMBL
  Q9QX79 ENTREZGENE
UniProt Secondary F1LN83 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Fetub  fetuin B  Fetub  fetuin beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-10-15 Fetub  fetuin beta  Fet_mapped  fetuin phosphoprotein (mapped)  Data merged from RGD:2601 737654 APPROVED
2005-11-17 Fet_mapped  fetuin phosphoprotein (mapped)  Fet  Fetuin (phosphoprotein, 63 kDa)  Symbol and Name updated 1556543 APPROVED
2002-06-10 Fet  Fetuin (phosphoprotein, 63 kDa)      Symbol and Name status set to approved 70586 APPROVED
2002-06-10 Fetub  fetuin beta      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction forms a fetuin-mineral complex with calcium phosphate and matrix Gla protein in vitro 1300185
gene_regulation down-regulated during experimentally induced inflammation 68778