Nr1i2 (nuclear receptor subfamily 1, group I, member 2) - Rat Genome Database

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Gene: Nr1i2 (nuclear receptor subfamily 1, group I, member 2) Mus musculus
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Symbol: Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
RGD ID: 69106
MGI Page MGI
Description: Enables nuclear receptor activity. Involved in cellular response to molecule of bacterial origin. Acts upstream of or within positive regulation of gene expression. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; genitourinary system; gut; liver; and nervous system. Orthologous to human NR1I2 (nuclear receptor subfamily 1 group I member 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: mP; mPXR; nuclear receptor subfamily 1 group I member 2; orphan nuclear receptor PXR; P; Pregnane X receptor; PXR; PXR.1; PXR.2; PXR1; S; SXR
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391638,068,711 - 38,115,211 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1638,068,685 - 38,115,186 (-)EnsemblGRCm39 Ensembl
GRCm381638,248,349 - 38,294,849 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1638,248,323 - 38,294,824 (-)EnsemblGRCm38mm10GRCm38
MGSCv371638,248,435 - 38,294,910 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361638,167,590 - 38,214,062 (-)NCBIMGSCv36mm8
Celera1638,657,356 - 38,703,953 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-artemisinin  (ISO)
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP,ISO)
(+)-trans-(S)-allethrin  (ISO)
(-)-secoisolariciresinol  (ISO)
(3-phenoxyphenyl)methanol  (EXP,ISO)
(E,E)-germacrone  (EXP,ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-naringenin  (ISO)
(Z)-ligustilide  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1-(3-chlorophenyl)piperazine  (ISO)
1-\{2-[(4-chlorobenzyl)sulfanyl]-2-(2,4-dichlorophenyl)ethyl\}-1H-imidazole  (ISO)
1-Hydroxypyrene  (EXP,ISO)
1-naphthol  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
10H-phenothiazine  (EXP,ISO)
13-cis-retinal  (ISO)
17alpha-ethynylestradiol  (ISO)
17alpha-hydroxyprogesterone  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-indole  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',4,4'-tetrachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,2'-Bisphenol F  (EXP,ISO)
2,2-diphenylacetic acid 2-(diethylamino)ethyl ester  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,3',4,4',5,5'-Heptachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,5-trichlorophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4-D  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-Dihydroxybenzophenone  (ISO)
2,5-di-tert-butylbenzene-1,4-diol  (ISO)
2,8-bis-Trifluoromethyl-4-quinoline carboxylic acid  (ISO)
2-(1-naphthalenylmethyl)-3-(2-oxolanyl)propanoic acid 2-(diethylamino)ethyl ester  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-acetamidofluorene  (EXP,ISO)
2-benzyl-4-chlorophenol  (ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
2-methyl-1H-indole  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5,5'-tetraiodothyroacetic acid  (ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,3'-diindolylmethane  (ISO)
3,3'-Dimethylbenzidine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,5-xylenol  (ISO)
3-iodoprop-2-yn-1-yl butylcarbamate  (EXP,ISO)
3-Methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one  (EXP,ISO)
3-oxo-5beta-cholanic acid  (ISO)
4'-epidoxorubicin  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile  (ISO)
4-chloro-3,5-dimethylphenol  (EXP,ISO)
4-hydroxy-3-(2-hydroxy-3-oxo-1-phenylbutyl)-2H-chromen-2-one  (ISO)
4-hydroxy-3-[1-(4-hydroxyphenyl)-3-oxobutyl]-2H-chromen-2-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-Methyl-3-penten-2-one, 9CI  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
4-tert-butylphenol  (EXP,ISO)
4-tert-Octylphenol  (ISO)
5,7-dihydroxy-4'-methoxyflavone  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-iodo-2'-deoxyuridine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
5alpha-pregnane-3,20-dione  (EXP,ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
8-(4-chlorophenylthio)-cAMP  (EXP)
8-Br-cAMP  (ISO)
9-cis-retinal  (ISO)
9-cis-retinoic acid  (ISO)
9-phenanthrol  (EXP,ISO)
acetamide  (ISO)
acetochlor  (EXP,ISO)
Acetyl tributyl citrate  (EXP,ISO)
aconitine  (ISO)
actinomycin D  (ISO)
adenine arabinoside  (ISO)
afimoxifene  (EXP,ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
Aflatoxin G1  (ISO)
aflatoxin M1  (ISO)
alachlor  (EXP,ISO)
aldehydo-D-glucose  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (ISO)
allocholic acid  (EXP)
allyl isothiocyanate  (ISO)
alpha-hexachlorocyclohexane  (EXP,ISO)
alpha-santonin  (ISO)
alpha-tocotrienol  (ISO)
aminoglutethimide  (ISO)
amiodarone  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
amprenavir  (ISO)
androst-4-ene-3,17-dione  (EXP,ISO)
androstane  (ISO)
angiotensin II  (EXP)
Anilofos  (EXP,ISO)
apazone  (ISO)
apigenin  (EXP,ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atazanavir sulfate  (ISO)
atorvastatin calcium  (EXP,ISO)
atrazine  (EXP)
azinphos-methyl  (ISO)
Azoxymethane  (EXP)
azoxystrobin  (EXP,ISO)
beclomethasone  (ISO)
Benfuresate  (ISO)
benidipine  (ISO)
bensulfuron-methyl  (ISO)
Bensulide  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[a]pyrene-7,8-diol  (ISO)
benzo[c]phenanthrene  (ISO)
benzophenone  (ISO)
Benzyl parahydroxybenzoate  (ISO)
berberine  (ISO)
bergomottin  (ISO)
Besigomsin  (ISO)
beta-carotene  (ISO)
beta-hexachlorocyclohexane  (ISO)
beta-naphthoflavone  (ISO)
beta-tocotrienol  (ISO)
bezafibrate  (ISO)
bicalutamide  (EXP,ISO)
bifenthrin  (EXP,ISO)
bilirubin IXalpha  (EXP,ISO)
biochanin A  (EXP,ISO)
bioresmethrin  (ISO)
biphenyl-2-ol  (ISO)
biphenyl-4-ol  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol A dimethacrylate  (ISO)
bisphenol AF  (EXP,ISO)
Bisphenol B  (ISO)
Bisphenol Z  (ISO)
bitertanol  (EXP,ISO)
brefeldin A  (ISO)
Bromadiolone  (EXP,ISO)
bromocresol purple  (ISO)
Bromophos-ethyl  (EXP,ISO)
bromothymol blue  (ISO)
Bromperidol  (ISO)
bromuconazole  (EXP,ISO)
budesonide  (ISO)
bupirimate  (ISO)
buspirone  (ISO)
buta-1,3-diene  (EXP)
butafenacil  (ISO)
Butamifos  (EXP,ISO)
butein  (ISO)
butoconazole  (ISO)
butylated hydroxyanisole  (EXP)
Butylbenzyl phthalate  (EXP,ISO)
Butylparaben  (ISO)
cafenstrole  (EXP)
calcitriol  (ISO)
camptothecin  (ISO)
captan  (ISO)
carbamazepine  (ISO)
carbamazepine-10,11-epoxide  (ISO)
carbaryl  (ISO)
carbon nanotube  (EXP)
cerivastatin  (ISO)
cetylpyridinium  (ISO)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
Chlomethoxyfen  (EXP,ISO)
chlordecone  (ISO)
chlorfenvinfos  (ISO)
chlornitrofen  (EXP,ISO)
Chlorobenzilate  (EXP,ISO)
Chloromethyl methyl ether  (EXP,ISO)
chloropropylate  (EXP,ISO)
chlorothalonil  (ISO)
chlorpromazine  (ISO)
chlorpropham  (ISO)
chlorpyrifos  (EXP,ISO)
chlorpyrifos-methyl  (EXP,ISO)
cholesterol  (EXP)
cholic acid  (EXP,ISO)
choline  (EXP,ISO)
chrysin  (EXP,ISO)
ciguatoxin CTX1B  (EXP)
cimetidine  (ISO)
cinchocaine  (ISO)
cisplatin  (ISO)
clemizole  (ISO)
clobetasol  (ISO)
clofibrate  (EXP,ISO)
clomiphene  (EXP,ISO)
clonazepam  (ISO)
clorgyline  (ISO)
clotrimazole  (EXP,ISO)
clozapine  (ISO)
cobicistat  (ISO)
colforsin daropate hydrochloride  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
coumaphos  (EXP,ISO)
coumestrol  (ISO)
Cryptotanshinone  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
Cyanofenphos  (EXP,ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP,ISO)
cyhalothrin  (EXP,ISO)
cypermethrin  (EXP,ISO)
cyproconazole  (ISO)
cyprodinil  (ISO)
cyproterone acetate  (EXP,ISO)
D-glucose  (ISO)
daidzein  (EXP,ISO)
DDD  (EXP,ISO)
DDE  (ISO)
DDT  (EXP,ISO)
decabromodiphenyl ether  (EXP,ISO)
Decamethylcyclopentasiloxane  (ISO)
dehydroepiandrosterone  (EXP,ISO)
delta-hexachlorocyclohexane  (ISO)
delta-tocotrienol  (ISO)
deoxycholic acid  (EXP,ISO)
Deoxyschizandrin  (EXP,ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diazepam  (ISO)
diazinon  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (EXP,ISO)
Dichlofenthion  (EXP,ISO)
diclofenac  (ISO)
dicloxacillin  (ISO)
dicofol  (EXP,ISO)
Dicyclohexyl phthalate  (EXP,ISO)
dieldrin  (EXP,ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
difenoconazole  (ISO)
diflubenzuron  (ISO)
dihydroergotamine  (ISO)
diisobutyl phthalate  (ISO)
Diisodecyl phthalate  (EXP,ISO)
diisononyl phthalate  (ISO)
dilazep  (ISO)
dimethomorph  (EXP,ISO)
dimethylarsinous acid  (ISO)
diniconazole  (EXP,ISO)
diosgenin  (EXP)
dioxygen  (ISO)
dipentyl phthalate  (EXP,ISO)
Diphenolic acid  (EXP,ISO)
diphenylamine  (ISO)
diquat  (EXP)
disopyramide  (ISO)
disulfiram  (EXP,ISO)
disulfoton  (EXP)
Dithiopyr  (EXP,ISO)
diuron  (EXP,ISO)
dodecylamine  (EXP,ISO)
doxorubicin  (ISO)
econazole  (ISO)
efavirenz  (ISO)
endosulfan  (EXP,ISO)
endrin  (EXP,ISO)
enilconazole  (EXP,ISO)
Enterolactone  (ISO)
EPN  (EXP,ISO)
epoxiconazole  (EXP)
equilin  (EXP,ISO)
erlotinib hydrochloride  (ISO)
estriol  (ISO)
estrone  (ISO)
Ethalfluralin  (EXP,ISO)
ethanol  (EXP,ISO)
ethion  (EXP,ISO)
ethoprophos  (EXP)
ethotoin  (ISO)
ethoxyquin  (EXP,ISO)
ethylparaben  (ISO)
eticlopride(1+)  (ISO)
etidronic acid  (ISO)
etofenprox  (EXP,ISO)
etoposide  (ISO)
eugenol  (ISO)
farglitazar  (ISO)
felodipine  (ISO)
fenamiphos  (EXP,ISO)
fenarimol  (EXP,ISO)
fenbuconazole  (ISO)
fenhexamid  (ISO)
fenitrothion  (EXP,ISO)
fenofibrate  (ISO)
fenthion  (EXP,ISO)
fentin chloride  (EXP,ISO)
fenvalerate  (EXP,ISO)
Fexofenadine hydrochloride  (ISO)
finasteride  (EXP,ISO)
fipronil  (EXP,ISO)
fisetin  (ISO)
flavonol  (EXP,ISO)
fluconazole  (ISO)
flucythrinate  (EXP,ISO)
fludioxonil  (EXP,ISO)
flufenacet  (ISO)
Flumetralin  (EXP,ISO)
flunisolide  (ISO)
fluoranthene  (EXP,ISO)
flutamide  (EXP,ISO)
fluticasone  (ISO)
flutolanil  (EXP,ISO)
fluvalinate  (EXP,ISO)
fluvastatin  (ISO)
folic acid  (EXP)
folpet  (EXP)
fulvestrant  (ISO)
galangin  (EXP,ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (EXP,ISO)
Ginkgolide A  (EXP,ISO)
ginkgolide B  (ISO)
glimepiride  (ISO)
glucose  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glycyrrhizinic acid  (ISO)
guggulsterone  (EXP,ISO)
GW 4064  (EXP)
heptachlor  (EXP,ISO)
Heptachlor epoxide  (EXP,ISO)
hesperetin  (ISO)
hexestrol  (ISO)
hycanthone  (ISO)
Hydrastine  (ISO)
hydroxyflutamide  (ISO)
hydroxyitraconazole  (ISO)
Hypaconitine  (ISO)
hyperforin  (ISO)
ifosfamide  (ISO)
Ile(5)-angiotensin II  (EXP)
imazamox  (ISO)
imidacloprid  (EXP)
imipenem hydrate  (ISO)
Indanofan  (EXP,ISO)
indole-3-acetamide  (ISO)
indoprofen  (ISO)
iprobenfos  (EXP,ISO)
iprodione  (EXP,ISO)
irinotecan  (EXP)
Isobutylparaben  (ISO)
Isoetharine  (ISO)
isofenphos  (EXP,ISO)
isoliquiritigenin  (ISO)
isopimpinellin  (EXP,ISO)
isoprothiolane  (EXP,ISO)
isoproturon  (ISO)
isorhamnetin  (EXP,ISO)
isotretinoin  (ISO)
isoxaben  (ISO)
isoxazoles  (ISO)
Isradipine  (ISO)
itraconazole  (ISO)
kaempferol  (EXP,ISO)
ketoconazole  (EXP,ISO)
kojic acid  (ISO)
L-methionine  (EXP,ISO)
lansoprazole  (ISO)
leflunomide  (ISO)
leptophos  (EXP,ISO)
levonorgestrel  (EXP,ISO)
lidocaine  (ISO)
lignan  (ISO)
linuron  (EXP,ISO)
lipopolysaccharide  (EXP)
lithocholic acid  (EXP,ISO)
loperamide  (ISO)
lovastatin  (ISO)
lycopene  (EXP)
Maleic hydrazide  (ISO)
MC-4379  (EXP,ISO)
mecarbam  (EXP,ISO)
Medazepam  (ISO)
medroxyprogesterone acetate  (ISO)
mefenacet  (EXP,ISO)
mefenamic acid  (ISO)
megestrol  (ISO)
melatonin  (EXP)
Melengestrol acetate  (EXP,ISO)
menaquinone  (ISO)
menaquinone-4  (ISO)
mephenytoin  (ISO)
mephobarbital  (ISO)
mercury dichloride  (ISO)
Mesaconitine  (ISO)
mestranol  (EXP,ISO)
metconazole  (EXP,ISO)
metformin  (EXP,ISO)
methacholine chloride  (EXP)
methapyrilene  (ISO)
methidathion  (ISO)
methiocarb  (ISO)
methotrexate  (ISO)
methoxsalen  (ISO)
methoxychlor  (EXP,ISO)
methyltestosterone  (ISO)
metolachlor  (EXP,ISO)
metolazone  (ISO)
metyrapone  (EXP,ISO)
mevastatin  (ISO)
miconazole  (ISO)
midazolam  (ISO)
mifepristone  (EXP,ISO)
Mitotane  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
monobenzone  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monocrotaline  (ISO)
monocrotophos  (ISO)
mycophenolic acid  (ISO)
N-nitrosodiethylamine  (ISO)
nabumetone  (ISO)
nafcillin  (ISO)
napropamide  (EXP,ISO)
nefazodone  (ISO)
nelfinavir  (ISO)
nicardipine  (ISO)
nifedipine  (ISO)
nilutamide  (EXP,ISO)
nimodipine  (ISO)
nitrofen  (EXP,ISO)
Nonylphenol  (EXP,ISO)
norethisterone  (EXP,ISO)
norgestrel  (ISO)
notoginsenoside R1  (EXP,ISO)
ochratoxin A  (ISO)
octamethylcyclotetrasiloxane  (ISO)
okadaic acid  (ISO)
oleanolic acid  (EXP,ISO)
omeprazole  (ISO)
orlistat  (ISO)
oryzalin  (EXP,ISO)
Oxadiazon  (EXP,ISO)
oxiconazole  (ISO)
oxolane  (EXP)
oxybenzone  (EXP,ISO)
oxybuprocaine  (ISO)
oxycodone  (ISO)
Oxyfluorfen  (EXP,ISO)
p-menthan-3-ol  (EXP)
p-tert-Amylphenol  (ISO)
paclitaxel  (EXP,ISO)
Panaxytriol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (EXP,ISO)
parathion-methyl  (EXP,ISO)
parthenolide  (ISO)
pazopanib  (ISO)
PCB138  (ISO)
penconazole  (ISO)
pencycuron  (ISO)
pendimethalin  (EXP,ISO)
pentachloronitrobenzene  (ISO)
pentachlorophenol  (EXP)
pentobarbital  (ISO)
perfluorobutanesulfonic acid  (ISO)
perfluorobutyric acid  (ISO)
perfluorodecanoic acid  (ISO)
perfluorododecanoic acid  (ISO)
perfluoroheptanoic acid  (ISO)
perfluorohexanesulfonic acid  (EXP,ISO)
perfluorohexanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanesulfonamide  (ISO)
perfluorooctanoic acid  (EXP,ISO)
perfluoropentanoic acid  (ISO)
perfluoroundecanoic acid  (ISO)
permethrin  (EXP,ISO)
phenanthrene  (EXP,ISO)
phenobarbital  (EXP,ISO)
phenolphthalein  (ISO)
phenothrin  (ISO)
Phenoxybenzamine  (ISO)
phenthoate  (EXP,ISO)
phenylephrine  (EXP)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosalone  (EXP,ISO)
phoxim  (EXP,ISO)
phthalic acid  (ISO)
picoxystrobin  (ISO)
pimecrolimus  (ISO)
pioglitazone  (ISO)
piperine  (ISO)
piperonyl butoxide  (EXP)
Piperophos  (EXP,ISO)
pirimiphos-methyl  (EXP)
pirinixic acid  (EXP)
PK-11195  (ISO)
prallethrin  (EXP,ISO)
pregnenolone  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
Pretilachlor  (EXP,ISO)
procaine  (ISO)
prochloraz  (EXP,ISO)
procymidone  (EXP,ISO)
progesterone  (ISO)
prometryn  (ISO)
propanil  (EXP,ISO)
propaphos  (EXP,ISO)
propargite  (EXP,ISO)
propiconazole  (EXP,ISO)
propranolol  (ISO)
propylparaben  (ISO)
propyzamide  (EXP,ISO)
prothiofos  (EXP,ISO)
pterostilbene  (ISO)
pyrene  (EXP,ISO)
pyrethrins  (EXP,ISO)
pyridaben  (EXP,ISO)
pyridaphenthion  (EXP,ISO)
pyrimethanil  (ISO)
quercetin  (EXP,ISO)
quinalphos  (EXP,ISO)
quinoxyfen  (ISO)
reserpine  (ISO)
resveratrol  (ISO)
rifabutin  (ISO)
rifampicin  (EXP,ISO)
rifaximin  (EXP,ISO)
Riluzole  (ISO)
risperidone  (ISO)
ritonavir  (ISO)
saquinavir  (ISO)
secobarbital  (ISO)
sevoflurane  (ISO)
silibinin  (ISO)
simvastatin  (ISO)
skatole  (ISO)
sodium arsenite  (EXP,ISO)
spironolactone  (EXP,ISO)
steviol  (ISO)
stilbene oxide  (ISO)
sulconazole  (ISO)
sulfamethazine  (ISO)
sulfinpyrazone  (ISO)
sulfluramid  (ISO)
sulforaphane  (ISO)
sulfoxaflor  (EXP)
tamarixetin  (EXP,ISO)
tamoxifen  (EXP,ISO)
Tanshinone I  (ISO)
tartrazine  (ISO)
taurocholic acid  (EXP,ISO)
tebuconazole  (EXP,ISO)
terbufos  (EXP,ISO)
terbutryn  (ISO)
terbutylazine  (ISO)
testosterone  (EXP,ISO)
Testosterone propionate  (EXP,ISO)
Tetrachlorobisphenol A  (ISO)
tetrachloromethane  (EXP,ISO)
tetrachlorvinphos  (EXP,ISO)
tetramethrin  (ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thiabendazole  (ISO)
Thiazopyr  (ISO)
thioacetamide  (ISO)
Thiobencarb  (EXP,ISO)
Thymophthalein  (ISO)
thyroxine  (ISO)
tiaprofenic acid  (ISO)
tiracizine  (ISO)
tiratricol  (ISO)
titanium dioxide  (EXP)
tolclofos-methyl  (ISO)
tolylfluanid  (ISO)
topiramate  (ISO)
toxaphene  (EXP,ISO)
tralomethrin  (EXP,ISO)
TRAM-34  (ISO)
trans-cinnamic acid  (ISO)
trenbolone  (ISO)
Tri-2-ethylhexyl trimellitate  (EXP,ISO)
triadimefon  (EXP,ISO)
Tributyl citrate  (ISO)
tributyl phosphate  (EXP,ISO)
tributylstannane  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (EXP,ISO)
triflumizole  (EXP,ISO)
trifluralin  (EXP,ISO)
trifluridine  (ISO)
triforine  (EXP,ISO)
trimethobenzamide  (ISO)
triphenyl phosphate  (EXP,ISO)
Triphenylethylene  (ISO)
Triptolide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
Tris(2-ethylhexyl) phosphate  (ISO)
triticonazole  (EXP,ISO)
troglitazone  (EXP,ISO)
troleandomycin  (ISO)
tryptamine  (ISO)
tryptophol  (ISO)
uranium atom  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valproic acid  (ISO)
verapamil  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (EXP,ISO)
vincristine  (ISO)
vitamin D  (ISO)
voriconazole  (EXP,ISO)
warfarin  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. Assem M, etal., J Biol Chem 2004 May 21;279(21):22250-7. Epub 2004 Mar 5.
2. Pregnane X receptor and constitutive androstane receptor modulate differently CYP3A-mediated metabolism in early- and late-stage cholestasis. Gabbia D, etal., World J Gastroenterol. 2017 Nov 14;23(42):7519-7530. doi: 10.3748/wjg.v23.i42.7519.
3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
4. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Pregnane X Receptor Not Nuclear Factor-kappa B Up-regulates P-glycoprotein Expression in the Brain of Chronic Epileptic Rats Induced by Kainic Acid. Yu N, etal., Neurochem Res. 2017 Aug;42(8):2167-2177. doi: 10.1007/s11064-017-2224-x. Epub 2017 Mar 16.
13. Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation. Zhang H, etal., Arch Biochem Biophys 1999 Aug 1;368(1):14-22.
14. Genetic polymorphisms in PXR and NF-κB1 influence susceptibility to anti-tuberculosis drug-induced liver injury. Zhang J, etal., PLoS One. 2019 Sep 6;14(9):e0222033. doi: 10.1371/journal.pone.0222033. eCollection 2019.
Additional References at PubMed
PMID:9489701   PMID:9727070   PMID:9770465   PMID:9784494   PMID:10349636   PMID:10628745   PMID:10935643   PMID:11002334   PMID:11005856   PMID:11042159   PMID:11076861   PMID:11248085  
PMID:11248086   PMID:11336976   PMID:11386755   PMID:11602523   PMID:11891224   PMID:11893771   PMID:12054576   PMID:12370413   PMID:12447992   PMID:12477932   PMID:12569201   PMID:12606758  
PMID:12644700   PMID:12774017   PMID:12837957   PMID:12881517   PMID:12909012   PMID:12923173   PMID:14742670   PMID:15183191   PMID:15340055   PMID:15347657   PMID:15358766   PMID:15364542  
PMID:15456840   PMID:15456926   PMID:15611112   PMID:15619241   PMID:15671183   PMID:15684063   PMID:15710363   PMID:15726644   PMID:16123326   PMID:16141072   PMID:16141073   PMID:16195250  
PMID:16219912   PMID:16297466   PMID:16498401   PMID:16556603   PMID:16606610   PMID:16614213   PMID:16682417   PMID:16691293   PMID:16825189   PMID:16837625   PMID:16841097   PMID:16844773  
PMID:16912278   PMID:16971476   PMID:16973756   PMID:17093002   PMID:17159084   PMID:17170021   PMID:17215127   PMID:17267396   PMID:17521389   PMID:17936928   PMID:18167061   PMID:18187584  
PMID:18242221   PMID:18287559   PMID:18648086   PMID:18677425   PMID:18703564   PMID:18778245   PMID:18794335   PMID:19141612   PMID:19141872   PMID:19144646   PMID:19162173   PMID:19183106  
PMID:19297428   PMID:19407337   PMID:19436068   PMID:19460945   PMID:19489075   PMID:19542321   PMID:19797606   PMID:19815629   PMID:19898264   PMID:19997066   PMID:20059953   PMID:20060928  
PMID:20173028   PMID:20185760   PMID:20211142   PMID:20354104   PMID:20403969   PMID:20416375   PMID:20693526   PMID:20876238   PMID:20932939   PMID:20979450   PMID:21127142   PMID:21203578  
PMID:21267068   PMID:21354151   PMID:21376070   PMID:21436254   PMID:21628639   PMID:21677750   PMID:21685500   PMID:21747170   PMID:21826054   PMID:21873635   PMID:21920351   PMID:21933665  
PMID:21983082   PMID:22166712   PMID:22285937   PMID:22371261   PMID:22467028   PMID:22496360   PMID:22496397   PMID:22503787   PMID:22698814   PMID:22790967   PMID:22815676   PMID:22917771  
PMID:23091169   PMID:23153560   PMID:23160821   PMID:23291432   PMID:23349477   PMID:23475203   PMID:23602807   PMID:23626729   PMID:23878263   PMID:24362030   PMID:24486481   PMID:24690595  
PMID:24755147   PMID:24863967   PMID:24952961   PMID:25065623   PMID:25749104   PMID:25811240   PMID:26013842   PMID:26159875   PMID:26265742   PMID:26363009   PMID:26416771   PMID:26574435  
PMID:26612838   PMID:26883953   PMID:27113289   PMID:27482056   PMID:27531557   PMID:27550658   PMID:28237809   PMID:28534176   PMID:28743453   PMID:28751364   PMID:28756207   PMID:28911860  
PMID:29107825   PMID:29123032   PMID:29142166   PMID:29212764   PMID:29360809   PMID:29425287   PMID:29718219   PMID:30102401   PMID:30193838   PMID:30573465   PMID:30593543   PMID:30677459  
PMID:30728326   PMID:30910785   PMID:31211619   PMID:31374856   PMID:31723190   PMID:31875848   PMID:31907988   PMID:32170024   PMID:32205367   PMID:32341518   PMID:32352317   PMID:32561593  
PMID:32660103   PMID:32798464   PMID:33076328   PMID:33387840   PMID:33687065   PMID:33777316   PMID:33782543   PMID:33828301   PMID:33879258   PMID:34303710   PMID:34830317   PMID:34851150  
PMID:34971590   PMID:35406689   PMID:35421365   PMID:35609418   PMID:36030841   PMID:36309199   PMID:36657504   PMID:36720308   PMID:37269088   PMID:37344564   PMID:37467962   PMID:37490003  
PMID:38032737   PMID:38428309   PMID:38788959  


Genomics

Comparative Map Data
Nr1i2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391638,068,711 - 38,115,211 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1638,068,685 - 38,115,186 (-)EnsemblGRCm39 Ensembl
GRCm381638,248,349 - 38,294,849 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1638,248,323 - 38,294,824 (-)EnsemblGRCm38mm10GRCm38
MGSCv371638,248,435 - 38,294,910 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361638,167,590 - 38,214,062 (-)NCBIMGSCv36mm8
Celera1638,657,356 - 38,703,953 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1626.64NCBI
NR1I2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383119,782,101 - 119,818,487 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3119,780,484 - 119,818,487 (+)EnsemblGRCh38hg38GRCh38
GRCh373119,500,948 - 119,537,334 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363120,982,021 - 121,020,022 (+)NCBINCBI36Build 36hg18NCBI36
Build 343120,982,020 - 121,020,021NCBI
Celera3117,908,432 - 117,946,438 (+)NCBICelera
Cytogenetic Map3q13.33NCBI
HuRef3116,874,950 - 116,913,074 (+)NCBIHuRef
CHM1_13119,462,845 - 119,500,855 (+)NCBICHM1_1
T2T-CHM13v2.03122,501,838 - 122,538,215 (+)NCBIT2T-CHM13v2.0
Nr1i2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81175,965,717 - 76,006,733 (+)NCBIGRCr8
mRatBN7.21162,460,213 - 62,496,665 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1162,460,213 - 62,496,658 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1171,272,711 - 71,309,163 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01163,934,940 - 63,971,386 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,985,406 - 63,021,853 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01165,022,100 - 65,058,546 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1165,022,100 - 65,058,545 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01167,024,185 - 67,060,494 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41164,239,918 - 64,276,702 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11164,297,534 - 64,333,716 (+)NCBI
Celera1161,960,674 - 61,997,009 (+)NCBICelera
Cytogenetic Map11q21NCBI
Nr1i2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542719,459,936 - 19,487,276 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542719,459,936 - 19,487,276 (+)NCBIChiLan1.0ChiLan1.0
NR1I2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22117,759,374 - 117,799,567 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13117,764,152 - 117,804,345 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03116,901,579 - 116,940,366 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13123,815,135 - 123,853,129 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3123,815,135 - 123,853,129 (+)Ensemblpanpan1.1panPan2
NR1I2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13323,444,367 - 23,456,405 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3323,432,690 - 23,455,347 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3323,474,457 - 23,486,487 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03323,682,177 - 23,694,192 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3323,669,760 - 23,694,177 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13323,486,165 - 23,498,350 (+)NCBIUMICH_Zoey_3.1
Nr1i2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602130,794,594 - 130,830,392 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365366,691,590 - 6,726,704 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365366,691,590 - 6,726,421 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR1I2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13140,364,075 - 140,406,112 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113140,373,571 - 140,406,129 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213149,710,912 - 149,743,466 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NR1I2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12261,005,404 - 61,043,016 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2261,006,667 - 61,040,832 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041105,267,620 - 105,304,705 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nr1i2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473128,371,707 - 28,381,357 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473128,371,707 - 28,405,327 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nr1i2
1101 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:409
Count of miRNA genes:306
Interacting mature miRNAs:353
Transcripts:ENSMUST00000023504
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11059560Lmr12b_mleishmaniasis resistance 12b (mouse)162879281362792952Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163544664392573008Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2277525257594076Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
11049571Lmr12c_mleishmaniasis resistance 12c (mouse)162879281362792952Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
11059559Lmr12a_mleishmaniasis resistance 12a (mouse)162879281362792952Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
4142187Arrd3_mage-related retinal degeneration 3 (mouse)Not determined3252290965466552Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
26884416Bzwq5_mbi-zygomatic width QTL 5, 5 week (mouse)163732036284696888Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
1301070Cypr1_mcytokine production 1 (mouse)Not determined163231279566312933Mouse
1300915Lmr12_mleishmaniasis resistance 12 (mouse)Not determined162879281362792952Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162193838355938574Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
15092062Egrme4_mearly growth rate, maternal effect 4 (mouse)162521866444220250Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
10412263Gvhd6_mgraft-versus host disease 6 (mouse)Not determined163606085745511148Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse

Markers in Region
AF031814  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381638,249,070 - 38,249,160UniSTSGRCm38
MGSCv371638,249,156 - 38,249,246UniSTSGRCm37
Celera1638,658,065 - 38,658,155UniSTS
Cytogenetic Map16B3UniSTS
Whitehead/MRC_RH16370.45UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001098404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_189595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006521848 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011245840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC154284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF031814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI595758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI746915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK011108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK018630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC120796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC137780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK383398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000023504   ⟹   ENSMUSP00000023504
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1638,068,685 - 38,115,186 (-)Ensembl
GRCm38.p6 Ensembl1638,248,323 - 38,294,824 (-)Ensembl
RefSeq Acc Id: NM_001098404   ⟹   NP_001091874
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,068,711 - 38,115,186 (-)NCBI
GRCm381638,248,349 - 38,294,824 (-)NCBI
MGSCv371638,248,435 - 38,294,910 (-)RGD
Celera1638,657,356 - 38,703,953 (-)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010936   ⟹   NP_035066
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,068,711 - 38,115,186 (-)NCBI
GRCm381638,248,349 - 38,294,824 (-)NCBI
MGSCv371638,248,435 - 38,294,910 (-)RGD
Celera1638,657,356 - 38,703,953 (-)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_189595
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,068,711 - 38,115,187 (-)NCBI
RefSeq Acc Id: XM_006521846   ⟹   XP_006521909
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,069,372 - 38,115,203 (-)NCBI
GRCm381638,249,010 - 38,294,841 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521847   ⟹   XP_006521910
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,071,497 - 38,115,201 (-)NCBI
GRCm381638,251,135 - 38,294,839 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006521848   ⟹   XP_006521911
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,069,372 - 38,115,211 (-)NCBI
GRCm381638,249,010 - 38,294,849 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245839   ⟹   XP_011244141
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,069,560 - 38,115,201 (-)NCBI
GRCm381638,249,198 - 38,294,839 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011245840   ⟹   XP_011244142
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391638,071,157 - 38,115,201 (-)NCBI
GRCm381638,250,795 - 38,294,839 (-)NCBI
Sequence:
RefSeq Acc Id: NP_035066   ⟸   NM_010936
- Peptide Label: isoform 1
- UniProtKB: O54915 (UniProtKB/Swiss-Prot),   Q0P525 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001091874   ⟸   NM_001098404
- Peptide Label: isoform 2
- UniProtKB: O54915 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006521911   ⟸   XM_006521848
- Peptide Label: isoform X1
- UniProtKB: O54915 (UniProtKB/Swiss-Prot),   Q0P525 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006521909   ⟸   XM_006521846
- Peptide Label: isoform X1
- UniProtKB: O54915 (UniProtKB/Swiss-Prot),   Q0P525 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006521910   ⟸   XM_006521847
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011244141   ⟸   XM_011245839
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011244142   ⟸   XM_011245840
- Peptide Label: isoform X4
- Sequence:
Ensembl Acc Id: ENSMUSP00000023504   ⟸   ENSMUST00000023504
Protein Domains
NR LBD   Nuclear receptor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O54915-F1-model_v2 AlphaFold O54915 1-431 view protein structure

Promoters
RGD ID:6827302
Promoter ID:MM_KWN:20971
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:NM_001098404,   OTTMUST00000057839
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361638,294,641 - 38,295,141 (-)MPROMDB
RGD ID:8686178
Promoter ID:EPDNEW_M21120
Type:initiation region
Name:Nr1i2_1
Description:Mus musculus nuclear receptor subfamily 1, group I, member 2, transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381638,294,798 - 38,294,858EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1337040 AgrOrtholog
Ensembl Genes ENSMUSG00000022809 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000023504 ENTREZGENE
  ENSMUST00000023504.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.50.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro NHR-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucl_hrmn_rcpt_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hormone_rcpt_NR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nuclear_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_hrmn_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_NHR/GATA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18171 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1337040 ENTREZGENE
NCBI Gene 18171 ENTREZGENE
PANTHER NUCLEAR HORMONE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_recep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB NR1I2 RGD
PhenoGen Nr1i2 PhenoGen
PRINTS STRDHORMONER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STROIDFINGER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NR_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCLEAR_REC_DBD_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOLI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_C4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48508 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt NR1I2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q0P525 ENTREZGENE, UniProtKB/TrEMBL
  Q9CRZ0_MOUSE UniProtKB/TrEMBL