Avpr1a (arginine vasopressin receptor 1A) - Rat Genome Database

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Gene: Avpr1a (arginine vasopressin receptor 1A) Mus musculus
Analyze
Symbol: Avpr1a
Name: arginine vasopressin receptor 1A
RGD ID: 68987
MGI Page MGI
Description: Predicted to enable V1A vasopressin receptor binding activity; peptide hormone binding activity; and vasopressin receptor activity. Involved in regulation of blood pressure. Acts upstream of or within regulation of systemic arterial blood pressure by vasopressin. Predicted to be located in endocytic vesicle and endosome. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Used to study schizophrenia. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human AVPR1A (arginine vasopressin receptor 1A).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: antidiuretic hormone receptor 1a; AVPR; AVPR V1a; Avpr1; V; V1a; V1a arginine vasopressin receptor; V1aR; vascular/hepatic-type arginine vasopressin receptor; vasopressin V1a receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910122,284,404 - 122,289,358 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10122,284,404 - 122,289,357 (+)EnsemblGRCm39 Ensembl
GRCm3810122,448,499 - 122,453,453 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10122,448,499 - 122,453,452 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710121,885,555 - 121,890,509 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610121,851,559 - 121,856,513 (+)NCBIMGSCv36mm8
Celera10124,830,307 - 124,835,265 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1070.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(+/-)-Aegeline  (EXP)
(1->4)-beta-D-glucan  (EXP)
(RS)-coclaurine  (EXP)
(RS)-norcoclaurine  (EXP)
(S)-coclaurine  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
2-butoxyethanol  (EXP)
3-chloropropane-1,2-diol  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
acetamide  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
argipressin  (ISO)
arsenite(3-)  (ISO)
Azoxymethane  (EXP)
Bardoxolone methyl  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bleomycin A2  (ISO)
bromobenzene  (ISO)
buta-1,3-diene  (EXP)
caffeine  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (EXP)
carbachol  (ISO)
carbon nanotube  (EXP)
carmustine  (ISO)
casticin  (EXP)
CGP 52608  (ISO)
chlorpyrifos  (EXP,ISO)
clofibrate  (EXP)
clofibric acid  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
cycloheximide  (ISO)
cyclosporin A  (EXP)
dextran sulfate  (EXP)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
etoposide  (ISO)
fenthion  (EXP)
flutamide  (ISO)
furan  (ISO)
glyphosate  (ISO)
GW 7647  (ISO)
indole-3-methanol  (ISO)
inulin  (EXP)
leflunomide  (ISO)
methotrexate  (EXP)
mono(2-ethylhexyl) phthalate  (EXP)
morphine  (EXP)
Muraglitazar  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosomorpholine  (ISO)
nefazodone  (ISO)
nicardipine  (ISO)
nimesulide  (ISO)
okadaic acid  (ISO)
ozone  (EXP)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenobarbital  (EXP,ISO)
pioglitazone  (EXP)
pirenzepine  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP,ISO)
ritodrine  (EXP)
rotenone  (ISO)
scopolamine  (ISO)
sevoflurane  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
tamoxifen  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetraphene  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topiramate  (ISO)
trichloroethene  (ISO)
trimellitic anhydride  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
XL147  (EXP)
yohimbine  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
endocytic vesicle  (IEA,ISO)
endosome  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Effects of novel vasopressin receptor antagonists on renal function and cardiac hypertrophy in rats with experimental congestive heart failure. Bishara B, etal., J Pharmacol Exp Ther. 2008 Aug;326(2):414-22. Epub 2008 May 8.
2. Enhanced involvement of brain vasopressin V1 receptors in cardiovascular responses to stress in rats with myocardial infarction. Dobruch J, etal., Stress. 2005 Dec;8(4):273-84.
3. Dissociation of the anxiolytic-like effects of Avpr1a and Avpr1b receptor antagonists in the dorsal and ventral hippocampus. Engin E and Treit D, Neuropeptides. 2008 Aug;42(4):411-21. Epub 2008 May 27.
4. Association of novel promoter single nucleotide polymorphisms in vasopressin V1a receptor gene with essential hypertension in nonobese Japanese. Hasan KN, etal., J Hum Hypertens. 2007 Oct;21(10):825-7. Epub 2007 Jul 26.
5. Science review: Vasopressin and the cardiovascular system part 1--receptor physiology. Holmes CL, etal., Crit Care. 2003 Dec;7(6):427-34. Epub 2003 Jun 26.
6. Altered expression of angiotensin AT1a and vasopressin V1a receptors and nitric oxide synthase mRNA in the brain of rats with renovascular hypertension. Jackiewicz E, etal., J Physiol Pharmacol. 2004 Dec;55(4):725-37.
7. Protective effect of the V1a receptor antagonist SR49059 on brain edema formation following middle cerebral artery occlusion in the rat. Kleindienst A, etal., Acta Neurochir Suppl. 2006;96:303-6.
8. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
9. MGDs mouse GO annotations MGD data from the GO Consortium
10. MGD IEA MGD IEA
11. Effects of the V1a vasopressin agonist F-180 on portal hypertension-related bleeding in portal hypertensive rats. Morales J, etal., Hepatology. 2003 Dec;38(6):1378-83.
12. Portal hypertension is associated with increased mRNA levels of vasopressor G-protein-coupled receptors in human hepatic arteries. Neef M, etal., Eur J Clin Invest. 2003 Mar;33(3):249-55.
13. Traumatic brain injury results in a concomitant increase in neocortical expression of vasopressin and its V1a receptor. Pascale CL, etal., J Physiol Pharmacol. 2006 Nov;57 Suppl 11:161-7.
14. Mineralocorticoid treatment upregulates the hypothalamic vasopressinergic system of spontaneously hypertensive rats. Pietranera L, etal., Neuroendocrinology. 2004;80(2):100-10. Epub 2004 Oct 6.
15. Mouse MP Annotation Import Pipeline RGD automated import pipeline
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Enhanced Ca2+ response to AVP in preglomerular vessels from rats with genetic hypertension during different hydration states. Vagnes OB, etal., Am J Physiol Renal Physiol. 2005 Jun;288(6):F1249-56. Epub 2005 Jan 18.
18. Alterations in central neuropeptide expression, release, and receptor binding in rats bred for high anxiety: critical role of vasopressin. Wigger A, etal., Neuropsychopharmacology 2004 Jan;29(1):1-14.
19. Early, but not late therapy with a vasopressin V1a-antagonist ameliorates the development of renal damage after 5/6 nephrectomy. Windt WA, etal., J Renin Angiotensin Aldosterone Syst. 2006 Dec;7(4):217-24.
Additional References at PubMed
PMID:10349636   PMID:10669045   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11955056   PMID:12466851   PMID:12477932   PMID:12486173   PMID:12576226   PMID:14647484  
PMID:15036628   PMID:15489334   PMID:15561968   PMID:16046007   PMID:16102534   PMID:16141072   PMID:16141073   PMID:16249339   PMID:16602821   PMID:16682631   PMID:16987237   PMID:17021052  
PMID:17049983   PMID:17083331   PMID:17224142   PMID:17227684   PMID:17275806   PMID:17303660   PMID:17379633   PMID:17449028   PMID:18305023   PMID:18448596   PMID:19052319   PMID:19375419  
PMID:19693000   PMID:20118201   PMID:20554879   PMID:21048978   PMID:21267068   PMID:21415155   PMID:21491433   PMID:21668734   PMID:21749489   PMID:21816902   PMID:21873635   PMID:22019732  
PMID:22300676   PMID:22811487   PMID:22820266   PMID:22968856   PMID:23261858   PMID:23671158   PMID:24009523   PMID:24092737   PMID:24167258   PMID:24345477   PMID:24641084   PMID:24924430  
PMID:24952961   PMID:24971321   PMID:25205804   PMID:25782631   PMID:26282397   PMID:26531127   PMID:26699482   PMID:26903624   PMID:27525673   PMID:27713143   PMID:28797033   PMID:28821809  
PMID:28911199   PMID:29231812   PMID:29713080   PMID:30290180   PMID:30916783   PMID:31547764   PMID:31758939   PMID:31836900   PMID:31915380   PMID:31961993   PMID:32884025   PMID:33320834  
PMID:33891950   PMID:34077719   PMID:35017259   PMID:36317965   PMID:36628861   PMID:36650057   PMID:37844254   PMID:38355793   PMID:38768798   PMID:38900750  


Genomics

Comparative Map Data
Avpr1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910122,284,404 - 122,289,358 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10122,284,404 - 122,289,357 (+)EnsemblGRCm39 Ensembl
GRCm3810122,448,499 - 122,453,453 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10122,448,499 - 122,453,452 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710121,885,555 - 121,890,509 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610121,851,559 - 121,856,513 (+)NCBIMGSCv36mm8
Celera10124,830,307 - 124,835,265 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1070.36NCBI
AVPR1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381263,142,759 - 63,151,201 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1263,142,759 - 63,151,201 (-)EnsemblGRCh38hg38GRCh38
GRCh371263,536,539 - 63,544,981 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361261,826,483 - 61,832,857 (-)NCBINCBI36Build 36hg18NCBI36
Build 341261,826,482 - 61,832,857NCBI
Celera1263,208,681 - 63,215,055 (-)NCBICelera
Cytogenetic Map12q14.2NCBI
HuRef1260,587,763 - 60,597,814 (-)NCBIHuRef
CHM1_11263,504,292 - 63,514,344 (-)NCBICHM1_1
T2T-CHM13v2.01263,121,411 - 63,352,402 (-)NCBIT2T-CHM13v2.0
Avpr1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8759,999,743 - 60,003,667 (+)NCBIGRCr8
mRatBN7.2758,114,306 - 58,118,230 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl758,114,284 - 58,122,215 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx759,986,073 - 59,990,009 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0762,188,888 - 62,192,822 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0761,966,702 - 61,970,636 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0767,341,366 - 67,345,290 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl767,341,080 - 67,345,308 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0767,528,358 - 67,532,282 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4762,225,537 - 62,229,461 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1762,246,266 - 62,250,191 (+)NCBI
Celera755,286,966 - 55,290,890 (+)NCBICelera
Cytogenetic Map7q22NCBI
Avpr1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545810,245,111 - 10,253,209 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545810,245,325 - 10,253,209 (-)NCBIChiLan1.0ChiLan1.0
AVPR1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21031,199,135 - 31,210,510 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11231,195,907 - 31,207,282 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01225,793,633 - 25,803,026 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11226,065,882 - 26,075,972 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1226,065,882 - 26,075,972 (+)Ensemblpanpan1.1panPan2
AVPR1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1106,266,217 - 6,269,662 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl106,265,998 - 6,269,662 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha106,196,083 - 6,199,528 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0106,304,782 - 6,308,218 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl106,304,563 - 6,308,218 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1106,244,666 - 6,248,110 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0106,496,014 - 6,499,452 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0106,633,959 - 6,637,404 (-)NCBIUU_Cfam_GSD_1.0
Avpr1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494552,314,128 - 52,323,553 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365451,786,571 - 1,794,709 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365451,788,995 - 1,795,842 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AVPR1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl527,824,992 - 27,832,703 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1527,824,991 - 27,832,794 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2530,773,944 - 30,779,983 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AVPR1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11159,074,699 - 59,079,710 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1159,071,202 - 59,079,596 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037186,727,383 - 186,736,923 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Avpr1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248024,894,235 - 4,900,276 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248024,893,172 - 4,900,177 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Avpr1a
205 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:289
Count of miRNA genes:250
Interacting mature miRNAs:258
Transcripts:ENSMUST00000020323
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884377Skwq3_mskull length QTL 3, 5 week (mouse)10114635905122735905Mouse
26884383Bzwq3_mbi-zygomatic width QTL 3, 5 week (mouse)10114235905122735905Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1018875748129635869Mouse
4142386Tgq20_mtriglyceride QTL 20 (mouse)Not determined88836456122836456Mouse
4141361Cfmq3_mcystic fibrosis modifier QTL 3 (mouse)Not determined10101497164130530862Mouse
4141487Tgq21_mtriglyceride QTL 21 (mouse)Not determined104110021130530862Mouse
4141742Psds4_mpsoriasis-like skin disease severity 4 (mouse)Not determined122041304124883196Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039175996129635869Mouse
1301895Exq1_mexploratory and excitability QTL 1 (mouse)Not determined10102847852130530862Mouse
14746996Manh69_mmandible shape 69 (mouse)10104763638130530862Mouse
1301901Im5_mimmunoregulatory 5 (mouse)Not determined10101497164130530862Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018259333125575232Mouse
11039496Ltpr5b_mLeishmania tropica response 5b (mouse)10108575094130530862Mouse
1357744Cfbw4_mcystic fibrosis body weight 4 (mouse)Not determined10100986516130530862Mouse
11041664Lmr25_mleishmaniasis resistance 25 (mouse)10108575094130530862Mouse
1302200Sle12_msystematic lupus erythematosus susceptibility 12 (mouse)Not determined10105041304130530862Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069735830130430862Mouse
11039516Ltpr5_mLeishmania tropica response 5 (mouse)1090506901125575232Mouse
27226795Scvln17_msacral vertebrae length 2, 16 week (mouse)10118435905124835905Mouse
4142089Obrq9_mobesity resistance QTL 9 (mouse)Not determined108515907130530862Mouse
27226791Feml8_mfemur length 8, 5 week (mouse)10119035905125735869Mouse
13506931Recrq11_mrecombination rate in male meiosis QTL 11 (mouse)10114335905123635905Mouse
1357482Nhdlq4_mnon-HDL QTL 4 (mouse)Not determined10105041304130530862Mouse
27226784Tibl4_mtibia length 4, 5 week (mouse)10119035905125435869Mouse
27226718Tibw3_mtibia width 3, proximal, 10 week (mouse)10118835905125435869Mouse
26884443Sklq5_mskull length QTL 5, 5 week (mouse)10119035905124835905Mouse
4142461Bmd25_mbone mineral density 25 (mouse)Not determined1097217101130530862Mouse
1301968Estq4_mestradiol regulated response QTL 4 (mouse)Not determined10100986516130530862Mouse
27095902Scvln11_msacral vertebrae length 2, 10 week (mouse)10110035861125435869Mouse
11353838Gluq3_mblood glucose QTL 3 (mouse)10120243727125515907Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1073987216125515907Mouse
11353834Pcholq2_mplasma cholesterol QTL 2 (mouse)10120243727125515907Mouse
11049570Lmr25b_mleishmaniasis resistance 25b (mouse)10108575094130530862Mouse
26884433Zlq2_mzygomatic length QTL 2, 5 week (mouse)10113535905125735869Mouse
11533921Mvb2_mmodifier of vibrator 2 (mouse)1097217101130530862Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1067835830124835905Mouse
1300679Nociq2_mnociceptive sensitivity inflammatory QTL 2 (mouse)Not determined10105041304130530862Mouse
1300678Leg2_mlongevity extending gene 2 (mouse)Not determined10102506908130530862Mouse
1301701Aggr1_maggression 1 (mouse)Not determined10119506908125575232Mouse
12880413V125Dq9_mvitamin D active form serum level QTL 9 (mouse)1097535905130530862Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1073987216125515907Mouse
4141153Ltgq2_mliver triglyceride QTL 2 (mouse)Not determined108515907130530862Mouse
27226747Metcl10_mmetatarsal-calcaneal length 10, 10 week (mouse)10119035905124835905Mouse
4141402T2dm1sa_mtype 2 diabetes mellitus 1 in SMXA RI mice (mouse)Not determined97758644130530862Mouse
27226742Metcl4_mmetatarsal-calcaneal length 4, 5 week (mouse)10118135905125435869Mouse
27095926Pglq4_mpelvic girdle length QTL 4, 5 week (mouse)10119035905124835905Mouse
1301758Fcsa3_mfemoral cross-sectional area 3 (mouse)Not determined1089927651123927754Mouse
27226736Metcl15_mmetatarsal-calcaneal length 15, 16 week (mouse)10119035905124835905Mouse
11533919Mvb4_mmodifier of vibrator 4 (mouse)397217101130530862Mouse
4141007Obrq10_mobesity resistance QTL 10 (mouse)Not determined103243727130530862Mouse
11353823Homaq2_mhomeostatic model assessment QTL 2 (mouse)10110453347125515907Mouse
11049563Lmr25a_mleishmaniasis resistance 25a (mouse)10108575094130530862Mouse
11353822Insq12_minsulin QTL 12 (mouse)10110453347125515907Mouse
14696727Kidrq2_mkidney weight, right QTL 2 (mouse)10102902508130530862Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059335822122335905Mouse
11040593Lmr5e_mleishmaniasis resistance 5e (mouse)1099220635130530862Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039175996129635869Mouse
27226725Tibw1_mtibia width 1, proximal, 5 week (mouse)10102735861123235905Mouse
11040594Lmr5f_mleishmaniasis resistance 5f (mouse)10105179713130530862Mouse
11040595Lmr5c_mleishmaniasis resistance 5c (mouse)1099220635130530862Mouse
1357544Vtbt10_mvertebral trabecular bone trait 10 (mouse)Not determined1097217101130530862Mouse
11040596Lmr5d_mleishmaniasis resistance 5d (mouse)10105179713130530862Mouse
11040597Lmr5a_mleishmaniasis resistance 5a (mouse)1099220635130530862Mouse
27226722Tibw7_mtibia width 7, proximal, 16 week (mouse)10108635861125435869Mouse
11040598Lmr5b_mleishmaniasis resistance 5b (mouse)10105179713130530862Mouse
27095906Scvln5_msacral vertebrae length 2, 5 week (mouse)10119035905124835905Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000020323   ⟹   ENSMUSP00000020323
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl10122,284,404 - 122,289,357 (+)Ensembl
GRCm38.p6 Ensembl10122,448,499 - 122,453,452 (+)Ensembl
RefSeq Acc Id: NM_016847   ⟹   NP_058543
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3910122,284,404 - 122,289,358 (+)NCBI
GRCm3810122,448,499 - 122,453,453 (+)ENTREZGENE
MGSCv3710121,885,555 - 121,890,509 (+)RGD
Celera10124,830,307 - 124,835,265 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_058543   ⟸   NM_016847
- UniProtKB: Q62464 (UniProtKB/Swiss-Prot),   Q9QYH2 (UniProtKB/Swiss-Prot),   Q62463 (UniProtKB/Swiss-Prot),   Q3U1H9 (UniProtKB/TrEMBL),   Q3UEE1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000020323   ⟸   ENSMUST00000020323
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62463-F1-model_v2 AlphaFold Q62463 1-423 view protein structure

Promoters
RGD ID:6819034
Promoter ID:MM_KWN:5816
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver,   MEF_B6
Transcripts:ENSMUST00000020323
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3610121,885,289 - 121,885,789 (+)MPROMDB
RGD ID:8673418
Promoter ID:EPDNEW_M14738
Type:initiation region
Name:Avpr1a_1
Description:Mus musculus arginine vasopressin receptor 1A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3810122,448,540 - 122,448,600EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1859216 AgrOrtholog
Ensembl Genes ENSMUSG00000020123 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020323 ENTREZGENE
  ENSMUST00000020323.7 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro DUF1856 UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Vasoprsn_rcpt UniProtKB/Swiss-Prot
  Vprs_V1A_rcpt UniProtKB/Swiss-Prot
KEGG Report mmu:54140 UniProtKB/Swiss-Prot
MGD MGI:1859216 ENTREZGENE
NCBI Gene 54140 ENTREZGENE
PANTHER NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot
  VASOPRESSIN V1A RECEPTOR UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
  DUF1856 UniProtKB/Swiss-Prot
PhenoGen Avpr1a PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  VASOPRESSINR UniProtKB/Swiss-Prot
  VASOPRSNV1AR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
SMART DUF1856 UniProtKB/Swiss-Prot
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt Q3U1H9 ENTREZGENE, UniProtKB/TrEMBL
  Q3UEE1 ENTREZGENE, UniProtKB/TrEMBL
  Q62463 ENTREZGENE
  Q62464 ENTREZGENE
  Q9QYH2 ENTREZGENE
  V1AR_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q62464 UniProtKB/Swiss-Prot
  Q9QYH2 UniProtKB/Swiss-Prot