AGTR1 Human (+)-pilocarpine multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of AGTR1A protein] CTD PMID:32494933 AGTR1 Human (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AGTR1 mRNA more ... CTD PMID:22079256 and PMID:36162953 AGTR1 Human (1->4)-beta-D-glucan multiple interactions ISO Agtr1a (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of AGTR1A mRNA CTD PMID:36331819 AGTR1 Human (R)-lipoic acid multiple interactions ISO Agtr1a (Mus musculus) 6480464 Thioctic Acid affects the reaction [Dietary Fats affects the expression of AGTR1A mRNA] CTD PMID:27260466 AGTR1 Human (R)-lipoic acid multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Thioctic Acid inhibits the reaction [Sodium Chloride and Dietary results in increased expression of AGTR1] CTD PMID:26518973 AGTR1 Human (S)-nicotine increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Nicotine results in increased expression of AGTR1A protein CTD PMID:22691361 AGTR1 Human 1,1-dichloroethene decreases expression ISO Agtr1a (Mus musculus) 6480464 vinylidene chloride results in decreased expression of AGTR1A mRNA CTD PMID:26682919 AGTR1 Human 1,2-dimethylhydrazine decreases expression ISO Agtr1a (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of AGTR1A mRNA CTD PMID:22206623 AGTR1 Human 1,2-dimethylhydrazine multiple interactions ISO Agtr1a (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of AGTR1A mRNA] CTD PMID:22206623 AGTR1 Human 1-naphthyl isothiocyanate decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in decreased expression of AGTR1A mRNA CTD PMID:25380136 AGTR1 Human 1-naphthyl isothiocyanate multiple interactions EXP 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of AGTR1 mRNA CTD PMID:27344345 AGTR1 Human 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine increases expression EXP 6480464 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine results in increased expression of AGTR1 mRNA CTD PMID:16386258 AGTR1 Human 17alpha-ethynylestradiol decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Ethinyl Estradiol results in decreased expression of AGTR1A mRNA CTD PMID:17351261 and PMID:17557909 AGTR1 Human 17beta-estradiol multiple interactions EXP 6480464 Estradiol inhibits the reaction [AGT protein results in increased expression of AGTR1 mRNA] and Estradiol inhibits the reaction [AGT protein results in increased expression of AGTR1 protein] CTD PMID:16097371 AGTR1 Human 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of AGTR1 mRNA CTD PMID:15159206 more ... AGTR1 Human 17beta-estradiol increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Estradiol results in increased expression of AGTR1 mRNA and Estradiol results in increased expression of AGTR1A mRNA CTD PMID:17021606 and PMID:32145629 AGTR1 Human 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Agtr1a (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 AGTR1 Human 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Agtr1a (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 AGTR1 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Agtr1a (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AGTR1A mRNA CTD PMID:19770486 AGTR1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Agtr1a (Rattus norvegicus) 401793709 2 more ... RGD AGTR1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of AGTR1A mRNA CTD PMID:34747641 AGTR1 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of AGTR1 mRNA CTD PMID:20106945 and PMID:21632981 AGTR1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of AGTR1 mRNA CTD PMID:22298810 AGTR1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of AGTR1A mRNA] CTD PMID:21215274 AGTR1 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AGTR1A mRNA CTD PMID:21215274 and PMID:33387578 AGTR1 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Agtr1a (Mus musculus) 6480464 2 more ... CTD PMID:38648751 AGTR1 Human 2,5-dihydroxybenzoic acid multiple interactions ISO Agtr1a (Mus musculus) 6480464 2 and 5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA] CTD PMID:37120126 AGTR1 Human 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine increases expression EXP 6480464 Platelet Activating Factor results in increased expression of AGTR1 mRNA CTD PMID:16386258 AGTR1 Human 2-butoxyethanol increases expression ISO Agtr1a (Mus musculus) 6480464 n-butoxyethanol results in increased expression of AGTR1A mRNA CTD PMID:19812364 AGTR1 Human 2-palmitoylglycerol increases expression EXP 6480464 2-palmitoylglycerol results in increased expression of AGTR1 mRNA CTD PMID:37199045 AGTR1 Human 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:14962509 AGTR1 Human 3,3',4,4'-tetrachlorobiphenyl increases expression ISO Agtr1a (Mus musculus) 6480464 3 more ... CTD PMID:21925196 AGTR1 Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AGTR1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AGTR1 mRNA CTD PMID:28628672 AGTR1 Human 3H-1,2-dithiole-3-thione decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in decreased expression of AGTR1A mRNA CTD PMID:19162173 AGTR1 Human 4,4'-diaminodiphenylmethane decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of AGTR1A mRNA CTD PMID:25380136 AGTR1 Human 4,4'-sulfonyldiphenol increases methylation EXP 6480464 bisphenol S results in increased methylation of AGTR1 gene CTD PMID:31601247 AGTR1 Human 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Fadrozole results in decreased expression of AGTR1 protein CTD PMID:18586661 AGTR1 Human 4-hydroxy-TEMPO multiple interactions ISO Agtr1a (Mus musculus) 6480464 tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 AGTR1 Human 4-hydroxyphenyl retinamide increases expression ISO Agtr1a (Mus musculus) 6480464 Fenretinide results in increased expression of AGTR1 mRNA CTD PMID:28973697 AGTR1 Human 5-aza-2'-deoxycytidine increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Decitabine results in increased expression of AGTR1 protein CTD PMID:34536542 AGTR1 Human 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Omeprazole affects the expression of AGTR1A mRNA CTD PMID:19483382 AGTR1 Human 6-propyl-2-thiouracil affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Propylthiouracil affects the expression of AGTR1A mRNA CTD PMID:19483382 AGTR1 Human 6-propyl-2-thiouracil decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of AGTR1A mRNA CTD PMID:25825206 AGTR1 Human 6-propyl-2-thiouracil increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of AGTR1A mRNA CTD PMID:24780913 AGTR1 Human 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO Agtr1a (Mus musculus) 6480464 APLN protein modified form inhibits the reaction [Uric Acid results in increased expression of AGTR1A mRNA] CTD PMID:30710622 AGTR1 Human 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression ISO Agtr1a (Mus musculus) 6480464 Uric Acid results in increased expression of AGTR1A mRNA CTD PMID:30710622 AGTR1 Human 8-Br-cAMP decreases expression EXP 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AGTR1 mRNA CTD PMID:22079614 AGTR1 Human Ac-Ser-Asp-Lys-Pro-OH multiple interactions ISO Agtr1a (Mus musculus) 6480464 ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]] more ... CTD PMID:33007385 AGTR1 Human acetylsalicylic acid multiple interactions ISO Agtr1a (Mus musculus) 6480464 Aspirin inhibits the reaction [Hydrogen Peroxide results in increased expression of AGTR1A mRNA] CTD PMID:22306536 AGTR1 Human aflatoxin B1 decreases expression ISO Agtr1a (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of AGTR1A mRNA CTD PMID:19770486 AGTR1 Human aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of AGTR1 gene CTD PMID:27153756 AGTR1 Human aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of AGTR1 mRNA CTD PMID:22100608 AGTR1 Human aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of AGTR1 protein CTD PMID:20106945 AGTR1 Human aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of AGTR1 mRNA and Glucose results in increased expression of AGTR1 protein CTD PMID:16452552 more ... AGTR1 Human aldehydo-D-glucose multiple interactions ISO Agtr1a (Mus musculus) 6480464 CEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CTD PMID:29266779 AGTR1 Human aldehydo-D-glucose increases expression ISO Agtr1a (Mus musculus) 6480464 Glucose results in increased expression of AGTR1 protein CTD PMID:29266779 AGTR1 Human aldehydo-D-glucose multiple interactions EXP 6480464 Enalaprilat inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CTD PMID:16452552 AGTR1 Human aldosterone multiple interactions EXP 6480464 [Losartan results in decreased activity of AGTR1 protein] which results in decreased abundance of Aldosterone CTD PMID:9124547 AGTR1 Human aldosterone increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Aldosterone results in increased expression of AGTR1A mRNA CTD PMID:15302841 and PMID:9087624 AGTR1 Human all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of AGTR1 mRNA CTD PMID:21934132 AGTR1 Human all-trans-retinoic acid multiple interactions ISO Agtr1a (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of AGTR1A mRNA CTD PMID:36189433 AGTR1 Human all-trans-retinoic acid increases expression ISO Agtr1a (Mus musculus) 6480464 Tretinoin results in increased expression of AGTR1A mRNA CTD PMID:36189433 AGTR1 Human all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of AGTR1 mRNA CTD PMID:23724009 AGTR1 Human AM6545 multiple interactions ISO Agtr1a (Mus musculus) 6480464 [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein] more ... CTD PMID:30184259 AGTR1 Human amiodarone affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Amiodarone affects the expression of AGTR1A mRNA CTD PMID:19483382 AGTR1 Human amlodipine decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Amlodipine results in decreased expression of AGTR1A mRNA CTD PMID:18403896 AGTR1 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Agtr1a (Mus musculus) 6480464 pyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of AGTR1 mRNA] CTD PMID:23603059 AGTR1 Human antirheumatic drug increases expression EXP 6480464 Antirheumatic Agents results in increased expression of AGTR1 mRNA CTD PMID:24449571 AGTR1 Human Aroclor 1254 decreases expression ISO Agtr1a (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of AGTR1A mRNA CTD PMID:25270620 AGTR1 Human arsenite(3-) increases methylation EXP 6480464 arsenite results in increased methylation of AGTR1 promoter CTD PMID:23974009 AGTR1 Human arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of AGTR1 mRNA CTD PMID:26705709 AGTR1 Human asbestos decreases expression EXP 6480464 Asbestos results in decreased expression of AGTR1 mRNA CTD PMID:22398240 AGTR1 Human aspartame decreases expression EXP 6480464 Aspartame results in decreased expression of AGTR1 mRNA CTD PMID:31655124 AGTR1 Human ATP multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Adenosine Triphosphate results in decreased expression of and results in decreased activity of AGTR1A protein more ... CTD PMID:21464294 AGTR1 Human ATP decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Adenosine Triphosphate results in decreased expression of AGTR1A mRNA CTD PMID:21464294 AGTR1 Human benazepril decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 benazepril results in decreased expression of AGTR1A mRNA and benazepril results in decreased expression of AGTR1A protein CTD PMID:9596920 AGTR1 Human benazepril multiple interactions EXP 6480464 [AGT gene polymorphism co-treated with AGTR1 gene polymorphism] affects the susceptibility to benazepril CTD PMID:21449848 AGTR1 Human benazepril multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 benazepril inhibits the reaction [Doxorubicin results in increased expression of AGTR1 protein] CTD PMID:15157388 AGTR1 Human benzbromarone affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Benzbromarone affects the expression of AGTR1A mRNA CTD PMID:19483382 AGTR1 Human benzo[a]pyrene decreases expression ISO Agtr1a (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of AGTR1A mRNA CTD PMID:22228805 AGTR1 Human benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of AGTR1 mRNA CTD PMID:32234424 AGTR1 Human benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of AGTR1 exon and Benzo(a)pyrene results in increased methylation of AGTR1 promoter CTD PMID:27901495 AGTR1 Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of AGTR1 5' UTR CTD PMID:27901495 AGTR1 Human beta-hexachlorocyclohexane decreases expression ISO Agtr1a (Mus musculus) 6480464 beta-hexachlorocyclohexane results in decreased expression of AGTR1A mRNA CTD PMID:25270620 AGTR1 Human bis(2-ethylhexyl) phthalate increases expression ISO Agtr1a (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of AGTR1A mRNA CTD PMID:34319233 AGTR1 Human bisphenol A decreases expression ISO Agtr1a (Mus musculus) 6480464 bisphenol A results in decreased expression of AGTR1A mRNA CTD PMID:21932408 and PMID:33221593 AGTR1 Human bisphenol A decreases methylation EXP 6480464 bisphenol A results in decreased methylation of AGTR1 gene CTD PMID:31601247 AGTR1 Human bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of AGTR1 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AGTR1 mRNA CTD PMID:28628672 and PMID:31601247 AGTR1 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of AGTR1 mRNA CTD PMID:27685785 AGTR1 Human bisphenol A decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of AGTR1 mRNA and bisphenol A results in decreased expression of AGTR1A mRNA CTD PMID:25181051 and PMID:30816183 AGTR1 Human bleomycin A2 increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Bleomycin results in increased expression of AGTR1 protein CTD PMID:20581171 AGTR1 Human bleomycin A2 multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of AGTR1 protein] CTD PMID:20581171 AGTR1 Human butanal decreases expression EXP 6480464 butyraldehyde results in decreased expression of AGTR1 mRNA CTD PMID:26079696 AGTR1 Human cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of AGTR1 mRNA CTD PMID:38382870 AGTR1 Human caffeine increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Caffeine results in increased expression of AGTR1A CTD PMID:25986755 AGTR1 Human caffeine decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Caffeine results in decreased expression of AGTR1A mRNA CTD PMID:30423288 AGTR1 Human calcium atom affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Calcium affects the expression of AGTR1A mRNA CTD PMID:15913539 AGTR1 Human calcium(0) affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Calcium affects the expression of AGTR1A mRNA CTD PMID:15913539 AGTR1 Human candesartan decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 candesartan results in decreased expression of AGTR1A mRNA CTD PMID:18796534 AGTR1 Human candesartan multiple interactions EXP 6480464 candesartan binds to and results in decreased activity of AGTR1 protein CTD PMID:21474964 AGTR1 Human candesartan multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 candesartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]] CTD PMID:15728788 AGTR1 Human Candesartan cilexetil multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 candesartan cilexetil binds to and results in decreased activity of AGTR1A protein CTD PMID:15667801 AGTR1 Human capsaicin increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Capsaicin results in increased expression of AGTR1A mRNA CTD PMID:20349343 AGTR1 Human captopril multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Captopril inhibits the reaction [Pregabalin results in increased expression of AGTR1 protein] CTD PMID:31629013 AGTR1 Human captopril multiple interactions ISO Agtr1a (Mus musculus) 6480464 Captopril inhibits the reaction [AGT protein results in increased expression of AGTR1 protein] more ... CTD PMID:28130181 and PMID:33007385 AGTR1 Human CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to AGTR1 gene] CTD PMID:28238834 AGTR1 Human chlordecone increases expression ISO Agtr1a (Mus musculus) 6480464 Chlordecone results in increased expression of AGTR1A mRNA CTD PMID:33711761 AGTR1 Human chlorpyrifos increases expression ISO Agtr1a (Mus musculus) 6480464 Chlorpyrifos results in increased expression of AGTR1A mRNA CTD PMID:37019170 AGTR1 Human cholesterol increases expression ISO Agtr1a (Mus musculus) 6480464 Cholesterol results in increased expression of AGTR1 mRNA CTD PMID:19028402 AGTR1 Human cholesterol multiple interactions ISO Agtr1a (Mus musculus) 6480464 Cholesterol inhibits the reaction [irbesartan results in increased expression of AGTR1 mRNA] CTD PMID:19028402 AGTR1 Human chromium(6+) affects expression EXP 6480464 chromium hexavalent ion affects the expression of AGTR1 mRNA CTD PMID:30690063 AGTR1 Human cilazapril monohydrate multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Cilazapril co-treated with Losartan] promotes the reaction [Doxorubicin results in increased expression of AGTR1 mRNA] and Cilazapril promotes the reaction [Doxorubicin results in increased expression of AGTR1 mRNA] CTD PMID:15331931 AGTR1 Human clofibrate affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Clofibrate affects the expression of AGTR1A mRNA CTD PMID:19483382 AGTR1 Human clofibric acid multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AGTR1A mRNA CTD PMID:17602206 AGTR1 Human cobalt dichloride decreases expression ISO Agtr1a (Mus musculus) 6480464 cobaltous chloride results in decreased expression of AGTR1 mRNA and cobaltous chloride results in decreased expression of AGTR1 protein CTD PMID:21825224 AGTR1 Human cobalt dichloride increases expression ISO Agtr1a (Mus musculus) 6480464 cobaltous chloride results in increased expression of AGTR1 mRNA CTD PMID:25511041 AGTR1 Human corticosterone multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Mifepristone inhibits the reaction [Corticosterone results in increased expression of AGTR1A mRNA] CTD PMID:30423288 AGTR1 Human corticosterone decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Corticosterone results in decreased expression of AGTR1A mRNA CTD PMID:30423288 AGTR1 Human cyclosporin A multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Cyclosporine inhibits the reaction [Adenosine Triphosphate results in decreased expression of AGTR1A mRNA] and Enalapril inhibits the reaction [Cyclosporine results in decreased expression of AGTR1A mRNA] CTD PMID:14659064 and PMID:21464294 AGTR1 Human cyclosporin A decreases methylation EXP 6480464 Cyclosporine results in decreased methylation of AGTR1 promoter CTD PMID:27989131 AGTR1 Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of AGTR1 mRNA CTD PMID:20106945 and PMID:25562108 AGTR1 Human cyclosporin A multiple interactions EXP 6480464 [Cyclosporine co-treated with Cholic Acids] affects the expression of AGTR1 mRNA CTD PMID:27344345 AGTR1 Human cyclosporin A decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Cyclosporine results in decreased expression of AGTR1A mRNA CTD PMID:14659064 AGTR1 Human D-glucose multiple interactions EXP 6480464 Enalaprilat inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CTD PMID:16452552 AGTR1 Human D-glucose multiple interactions ISO Agtr1a (Mus musculus) 6480464 CEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CTD PMID:29266779 AGTR1 Human D-glucose increases expression ISO Agtr1a (Mus musculus) 6480464 Glucose results in increased expression of AGTR1 protein CTD PMID:29266779 AGTR1 Human D-glucose increases expression EXP 6480464 Glucose results in increased expression of AGTR1 mRNA and Glucose results in increased expression of AGTR1 protein CTD PMID:16452552 more ... AGTR1 Human daunorubicin multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 telmisartan inhibits the reaction [Daunorubicin results in increased expression of AGTR1A protein] CTD PMID:20888384 AGTR1 Human daunorubicin increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Daunorubicin results in increased expression of AGTR1A protein CTD PMID:20888384 AGTR1 Human decabromodiphenyl ether increases expression ISO Agtr1a (Rattus norvegicus) 6480464 decabromobiphenyl ether results in increased expression of AGTR1A mRNA CTD PMID:23914054 AGTR1 Human decabromodiphenyl ether decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 decabromobiphenyl ether results in decreased expression of AGTR1A mRNA CTD PMID:23914054 AGTR1 Human dexamethasone increases expression ISO Agtr1a (Mus musculus) 6480464 Dexamethasone results in increased expression of AGTR1 protein and Dexamethasone results in increased expression of AGTR1A mRNA CTD PMID:23935943 and PMID:30940551 AGTR1 Human dexamethasone multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of AGTR1A protein] CTD PMID:32494933 AGTR1 Human dexamethasone increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Dexamethasone results in increased expression of AGTR1A mRNA and Dexamethasone results in increased expression of AGTR1A protein CTD PMID:32494933 AGTR1 Human dexamethasone affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Dexamethasone affects the expression of AGTR1 mRNA CTD PMID:30359671 AGTR1 Human dexamethasone multiple interactions ISO Agtr1a (Mus musculus) 6480464 diisononyl phthalate promotes the reaction [Dexamethasone results in increased expression of AGTR1 protein] more ... CTD PMID:30940551 AGTR1 Human dexamethasone multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AGTR1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AGTR1 mRNA CTD PMID:28628672 AGTR1 Human diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of AGTR1 mRNA CTD PMID:26705709 AGTR1 Human dibenz[a,h]anthracene increases expression ISO Agtr1a (Mus musculus) 6480464 1 more ... CTD PMID:26377693 AGTR1 Human dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of AGTR1 protein CTD PMID:37356649 AGTR1 Human diisononyl phthalate increases expression ISO Agtr1a (Mus musculus) 6480464 diisononyl phthalate results in increased expression of AGTR1 protein CTD PMID:30940551 AGTR1 Human diisononyl phthalate multiple interactions ISO Agtr1a (Mus musculus) 6480464 diisononyl phthalate promotes the reaction [Dexamethasone results in increased expression of AGTR1 protein] and Enalapril inhibits the reaction [diisononyl phthalate promotes the reaction [Dexamethasone results in increased expression of AGTR1 protein]] CTD PMID:30940551 AGTR1 Human diminazene diaceturate multiple interactions EXP 6480464 ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGTR1 mRNA]] and diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGTR1 mRNA] CTD PMID:26862037 AGTR1 Human dioxygen decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Oxygen deficiency results in decreased expression of AGTR1A mRNA and Oxygen deficiency results in decreased expression of AGTR1A protein CTD PMID:19118600 AGTR1 Human dioxygen decreases expression ISO Agtr1a (Mus musculus) 6480464 Oxygen deficiency results in decreased expression of AGTR1 protein CTD PMID:21825224 AGTR1 Human dioxygen multiple interactions ISO Agtr1a (Mus musculus) 6480464 Losartan inhibits the reaction [Oxygen deficiency results in increased expression of AGTR1 protein] CTD PMID:25511041 AGTR1 Human dioxygen affects expression ISO Agtr1a (Mus musculus) 6480464 Oxygen deficiency affects the expression of AGTR1 protein CTD PMID:25511041 AGTR1 Human dipentyl phthalate decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 di-n-pentyl phthalate results in decreased expression of AGTR1A mRNA and di-n-pentyl phthalate results in decreased expression of AGTR1A protein CTD PMID:36715143 AGTR1 Human diuron decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Diuron results in decreased expression of AGTR1A mRNA CTD PMID:25152437 AGTR1 Human doxorubicin increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of AGTR1 mRNA more ... CTD PMID:15157388 more ... AGTR1 Human doxorubicin multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Cilazapril co-treated with Losartan] promotes the reaction [Doxorubicin results in increased expression of AGTR1 mRNA] more ... CTD PMID:15157388 more ... AGTR1 Human EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Angiotensin-Converting Enzyme Inhibitors results in increased expression of AGTR1 mRNA CTD PMID:9533614 AGTR1 Human edaravone multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Edaravone inhibits the reaction [Lipopolysaccharides results in decreased expression of AGTR1A mRNA] CTD PMID:19118600 AGTR1 Human ellagic acid multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Ellagic Acid inhibits the reaction [AGT protein results in increased expression of AGTR1 protein] CTD PMID:38356441 AGTR1 Human enalapril affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Enalapril affects the expression of AGTR1A mRNA CTD PMID:18796534 AGTR1 Human enalapril multiple interactions ISO Agtr1a (Mus musculus) 6480464 Enalapril inhibits the reaction [Dexamethasone results in increased expression of AGTR1 protein] more ... CTD PMID:30940551 and PMID:36706861 AGTR1 Human enalapril multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Enalapril inhibits the reaction [Cyclosporine results in decreased expression of AGTR1A mRNA] CTD PMID:14659064 AGTR1 Human enalapril decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Enalapril results in decreased expression of AGTR1A mRNA CTD PMID:18403896 and PMID:18765277 AGTR1 Human enalapril increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Enalapril results in increased expression of AGTR1A mRNA CTD PMID:18796534 AGTR1 Human enalaprilat dihydrate multiple interactions EXP 6480464 Enalaprilat inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CTD PMID:16452552 AGTR1 Human endosulfan decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of AGTR1A mRNA CTD PMID:29391264 AGTR1 Human esculetin multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA] and esculetin inhibits the reaction [Dietary Fats results in increased expression of AGTR1A mRNA] CTD PMID:28946194 AGTR1 Human estriol decreases expression EXP 6480464 Estriol results in decreased expression of AGTR1 mRNA CTD PMID:15159206 AGTR1 Human ethanol increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Ethanol results in increased expression of AGTR1A mRNA CTD PMID:25151222 and PMID:29548890 AGTR1 Human ethanol decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Ethanol results in decreased expression of AGTR1A mRNA and Ethanol results in decreased expression of AGTR1A protein CTD PMID:31887396 AGTR1 Human ethanol multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Ethanol affects the reaction [Dietary Fats affects the expression of AGTR1 mRNA] and Ethanol affects the reaction [Dietary Fats affects the expression of AGTR1 protein] CTD PMID:31811911 AGTR1 Human flavonoids decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Flavonoids results in decreased expression of AGTR1A mRNA CTD PMID:18035473 AGTR1 Human folic acid multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 candesartan inhibits the reaction [Folic Acid results in increased localization of [AGT protein binds to AGTR1A protein]] more ... CTD PMID:15728788 AGTR1 Human folic acid decreases expression ISO Agtr1a (Mus musculus) 6480464 Folic Acid results in decreased expression of AGTR1A mRNA CTD PMID:25629700 AGTR1 Human folic acid multiple interactions ISO Agtr1a (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of AGTR1A mRNA] CTD PMID:22206623 AGTR1 Human formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of AGTR1 mRNA CTD PMID:28937961 AGTR1 Human formaldehyde multiple interactions ISO Agtr1a (Mus musculus) 6480464 Enalapril inhibits the reaction [Formaldehyde results in increased expression of AGTR1 protein] CTD PMID:36706861 AGTR1 Human formaldehyde increases expression ISO Agtr1a (Mus musculus) 6480464 Formaldehyde results in increased expression of AGTR1 protein CTD PMID:36706861 AGTR1 Human fructose increases expression ISO Agtr1a (Mus musculus) 6480464 Fructose results in increased expression of AGTR1A mRNA CTD PMID:16843071 AGTR1 Human fructose increases expression EXP 6480464 Fructose results in increased expression of AGTR1 mRNA CTD PMID:31655124 AGTR1 Human fructose multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGTR1A mRNA] and INS protein inhibits the reaction [Fructose results in increased expression of AGTR1A mRNA] CTD PMID:18360027 and PMID:30710622 AGTR1 Human fructose increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Fructose results in increased expression of AGTR1A mRNA CTD PMID:17587757 more ... AGTR1 Human fulvestrant multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of AGTR1 gene CTD PMID:31601247 AGTR1 Human gentamycin decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Gentamicins results in decreased expression of AGTR1A mRNA CTD PMID:33387578 AGTR1 Human glucose multiple interactions EXP 6480464 Enalaprilat inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CTD PMID:16452552 AGTR1 Human glucose increases expression ISO Agtr1a (Mus musculus) 6480464 Glucose results in increased expression of AGTR1 protein CTD PMID:29266779 AGTR1 Human glucose multiple interactions ISO Agtr1a (Mus musculus) 6480464 CEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CTD PMID:29266779 AGTR1 Human glucose increases expression EXP 6480464 Glucose results in increased expression of AGTR1 mRNA and Glucose results in increased expression of AGTR1 protein CTD PMID:16452552 more ... AGTR1 Human glycochenodeoxycholic acid multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 AGTR1 protein promotes the reaction [AGT protein inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]] and AGTR1 protein promotes the reaction [AGT protein results in decreased susceptibility to Glycochenodeoxycholic Acid] CTD PMID:23300732 AGTR1 Human glyoxylic acid increases expression ISO Agtr1a (Rattus norvegicus) 6480464 glyoxylic acid results in increased expression of AGTR1 protein CTD PMID:37454925 AGTR1 Human goralatide multiple interactions ISO Agtr1a (Mus musculus) 6480464 ACE2 protein affects the reaction [goralatide inhibits the reaction [AGT protein results in increased expression of AGTR1A protein]] more ... CTD PMID:33007385 AGTR1 Human Heptachlor epoxide decreases expression ISO Agtr1a (Mus musculus) 6480464 Heptachlor Epoxide results in decreased expression of AGTR1A mRNA CTD PMID:25270620 AGTR1 Human hexachlorobenzene increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Hexachlorobenzene results in increased expression of AGTR1 protein CTD PMID:29277037 AGTR1 Human hydrochlorothiazide decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Hydrochlorothiazide results in decreased expression of AGTR1A mRNA CTD PMID:18796534 AGTR1 Human hydrogen peroxide multiple interactions ISO Agtr1a (Mus musculus) 6480464 Aspirin inhibits the reaction [Hydrogen Peroxide results in increased expression of AGTR1A mRNA] and Losartan inhibits the reaction [Hydrogen Peroxide results in increased expression of AGTR1A mRNA] CTD PMID:22306536 AGTR1 Human hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of AGTR1 mRNA and Hydrogen Peroxide results in increased expression of AGTR1 protein CTD PMID:36162953 AGTR1 Human hydrogen peroxide multiple interactions EXP 6480464 epigallocatechin gallate promotes the reaction [Warfarin inhibits the reaction [Hydrogen Peroxide results in increased expression of AGTR1 mRNA]] more ... CTD PMID:36162953 AGTR1 Human hydrogen peroxide increases expression ISO Agtr1a (Mus musculus) 6480464 Hydrogen Peroxide results in increased expression of AGTR1A mRNA CTD PMID:22306536 and PMID:30710622 AGTR1 Human indole-3-methanol affects expression ISO Agtr1a (Rattus norvegicus) 6480464 indole-3-carbinol affects the expression of AGTR1A mRNA CTD PMID:21396975 AGTR1 Human indometacin multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of AGTR1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AGTR1 mRNA CTD PMID:28628672 AGTR1 Human inulin multiple interactions ISO Agtr1a (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of AGTR1A mRNA CTD PMID:36331819 AGTR1 Human irbesartan multiple interactions ISO Agtr1a (Mus musculus) 6480464 Cholesterol inhibits the reaction [irbesartan results in increased expression of AGTR1 mRNA] CTD PMID:19028402 AGTR1 Human irbesartan multiple interactions EXP 6480464 irbesartan binds to and results in decreased activity of AGTR1 protein CTD PMID:12022239 AGTR1 Human irbesartan affects response to substance EXP 6480464 AGTR1 gene polymorphism affects the susceptibility to irbesartan CTD PMID:11910301 AGTR1 Human isoprenaline decreases expression ISO Agtr1a (Mus musculus) 6480464 Isoproterenol results in decreased expression of AGTR1A mRNA CTD PMID:17350036 AGTR1 Human isotretinoin increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Isotretinoin results in increased expression of AGTR1 mRNA and Isotretinoin results in increased expression of AGTR1 protein CTD PMID:19212007 AGTR1 Human L-ethionine affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Ethionine affects the expression of AGTR1A mRNA CTD PMID:19483382 AGTR1 Human lipoic acid multiple interactions ISO Agtr1a (Mus musculus) 6480464 Thioctic Acid affects the reaction [Dietary Fats affects the expression of AGTR1A mRNA] CTD PMID:27260466 AGTR1 Human lipoic acid multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Thioctic Acid inhibits the reaction [Sodium Chloride and Dietary results in increased expression of AGTR1] CTD PMID:26518973 AGTR1 Human lipopolysaccharide multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Edaravone inhibits the reaction [Lipopolysaccharides results in decreased expression of AGTR1A mRNA] CTD PMID:19118600 AGTR1 Human lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of AGTR1 mRNA CTD PMID:26862037 AGTR1 Human lipopolysaccharide multiple interactions EXP 6480464 ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGTR1 mRNA]] and diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGTR1 mRNA] CTD PMID:26862037 AGTR1 Human lipopolysaccharide decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Lipopolysaccharides results in decreased expression of AGTR1A mRNA CTD PMID:19118600 AGTR1 Human lithium chloride multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Lithium Chloride co-treated with Pilocarpine] affects the reaction [Dexamethasone results in increased expression of AGTR1A protein] CTD PMID:32494933 AGTR1 Human losartan multiple interactions ISO Agtr1a (Mus musculus) 6480464 Losartan binds to and results in decreased activity of AGTR1A protein more ... CTD PMID:15528393 more ... AGTR1 Human losartan increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Losartan results in increased expression of AGTR1 mRNA and Losartan results in increased expression of AGTR1A mRNA CTD PMID:11893553 and PMID:9533614 AGTR1 Human losartan multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Cilazapril co-treated with Losartan] promotes the reaction [Doxorubicin results in increased expression of AGTR1 mRNA] more ... CTD PMID:12930639 more ... AGTR1 Human losartan decreases activity EXP 6480464 Losartan results in decreased activity of AGTR1 protein CTD PMID:9124547 AGTR1 Human losartan multiple interactions EXP 6480464 [Losartan results in decreased activity of AGTR1 protein] which results in decreased abundance of Aldosterone more ... CTD PMID:10821809 more ... AGTR1 Human losartan decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Losartan results in decreased expression of AGTR1 protein more ... CTD PMID:18300857 more ... AGTR1 Human Magnolol multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 magnolol inhibits the reaction [AGT protein binds to AGTR1A protein] and magnolol inhibits the reaction [Monocrotaline results in increased expression of AGTR1A protein] CTD PMID:30466619 AGTR1 Human mangiferin multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 mangiferin inhibits the reaction [AGT protein results in increased expression of AGTR1A mRNA] and mangiferin inhibits the reaction [AGT protein results in increased expression of AGTR1A protein] CTD PMID:17645561 and PMID:19706694 AGTR1 Human mechlorethamine multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Valproic Acid promotes the reaction [Mechlorethamine results in increased expression of AGTR1A mRNA] CTD PMID:28184907 AGTR1 Human mechlorethamine increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Mechlorethamine results in increased expression of AGTR1A mRNA CTD PMID:28184907 AGTR1 Human mercury dibromide increases expression EXP 6480464 mercuric bromide results in increased expression of AGTR1 mRNA CTD PMID:27188386 AGTR1 Human mercury dichloride increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Mercuric Chloride results in increased expression of AGTR1A mRNA CTD PMID:28987480 AGTR1 Human metformin multiple interactions ISO Agtr1a (Mus musculus) 6480464 Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA] CTD PMID:37120126 AGTR1 Human methamphetamine increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Methamphetamine results in increased expression of AGTR1A protein CTD PMID:33421459 AGTR1 Human mevinphos multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Mevinphos results in increased activity of AGTR1A protein] promotes the reaction [NOX1 protein results in increased abundance of Superoxides] CTD PMID:23824088 AGTR1 Human mevinphos increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Mevinphos results in increased expression of AGTR1A mRNA and Mevinphos results in increased expression of AGTR1A protein CTD PMID:23824088 AGTR1 Human mifepristone multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Mifepristone inhibits the reaction [Corticosterone results in increased expression of AGTR1A mRNA] CTD PMID:30423288 AGTR1 Human mono(2-ethylhexyl) phthalate multiple interactions ISO Agtr1a (Mus musculus) 6480464 [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of AGTR1A mRNA CTD PMID:36189433 AGTR1 Human monocrotaline increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Monocrotaline results in increased expression of AGTR1A protein CTD PMID:30466619 AGTR1 Human monocrotaline multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 magnolol inhibits the reaction [Monocrotaline results in increased expression of AGTR1A protein] CTD PMID:30466619 AGTR1 Human N-acetyl-L-cysteine multiple interactions ISO Agtr1a (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of AGTR1 mRNA] CTD PMID:23603059 AGTR1 Human N-nitrosodiethylamine multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AGTR1A mRNA CTD PMID:17602206 AGTR1 Human N-nitrosodimethylamine decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Dimethylnitrosamine results in decreased expression of AGTR1A mRNA CTD PMID:25380136 AGTR1 Human Nandrolone decanoate increases expression ISO Agtr1a (Rattus norvegicus) 6480464 nandrolone decanoate results in increased expression of AGTR1A mRNA CTD PMID:17906098 AGTR1 Human nerolidol multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 nerolidol inhibits the reaction [AGT protein results in increased expression of AGTR1A protein] CTD PMID:33212213 AGTR1 Human nickel atom decreases expression EXP 6480464 Nickel results in decreased expression of AGTR1 mRNA CTD PMID:25583101 AGTR1 Human nicotinamide multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Niacinamide results in decreased activity of SIRT1 protein] inhibits the reaction [resveratrol results in decreased expression of AGTR1 mRNA] and [Niacinamide results in decreased activity of SIRT1 protein] which results in increased expression of AGTR1 mRNA CTD PMID:18420994 AGTR1 Human nicotinamide multiple interactions ISO Agtr1a (Mus musculus) 6480464 2 more ... CTD PMID:37120126 AGTR1 Human nicotine increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Nicotine results in increased expression of AGTR1A protein CTD PMID:22691361 AGTR1 Human nitrendipine affects response to substance EXP 6480464 AGTR1 gene SNP affects the susceptibility to Nitrendipine CTD PMID:8952600 AGTR1 Human nitric oxide affects abundance ISO Agtr1a (Rattus norvegicus) 6480464 AGTR1A protein affects the abundance of Nitric Oxide CTD PMID:19151255 AGTR1 Human nitrofen decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 nitrofen results in decreased expression of AGTR1A mRNA CTD PMID:15578192 and PMID:16292651 AGTR1 Human nitrofen increases expression ISO Agtr1a (Rattus norvegicus) 6480464 nitrofen results in increased expression of AGTR1A mRNA CTD PMID:33484710 AGTR1 Human olmesartan decreases activity EXP 6480464 olmesartan results in decreased activity of AGTR1 protein CTD PMID:17208988 AGTR1 Human omeprazole affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Omeprazole affects the expression of AGTR1A mRNA CTD PMID:19483382 AGTR1 Human ouabain affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Ouabain affects the expression of AGTR1A mRNA CTD PMID:16565308 AGTR1 Human ouabain decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Ouabain results in decreased expression of AGTR1A protein CTD PMID:16565308 AGTR1 Human oxaliplatin multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of AGTR1A mRNA CTD PMID:25729387 AGTR1 Human ozone increases expression ISO Agtr1a (Mus musculus) 6480464 Ozone results in increased expression of AGTR1 protein CTD PMID:27679563 AGTR1 Human ozone multiple interactions ISO Agtr1a (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of AGTR1A mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of AGTR1A mRNA CTD PMID:34911549 AGTR1 Human ozone increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Ozone results in increased expression of AGTR1 mRNA CTD PMID:26667334 AGTR1 Human paracetamol decreases expression ISO Agtr1a (Mus musculus) 6480464 Acetaminophen results in decreased expression of AGTR1A mRNA CTD PMID:11752693 AGTR1 Human paracetamol decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of AGTR1A mRNA CTD PMID:33387578 AGTR1 Human paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of AGTR1 mRNA CTD PMID:21420995 and PMID:22230336 AGTR1 Human paraquat increases expression EXP 6480464 Paraquat results in increased expression of AGTR1 mRNA and Paraquat results in increased expression of AGTR1 protein CTD PMID:20035857 AGTR1 Human PCB138 multiple interactions ISO Agtr1a (Mus musculus) 6480464 [2 more ... CTD PMID:25510870 AGTR1 Human pentanal decreases expression EXP 6480464 pentanal results in decreased expression of AGTR1 mRNA CTD PMID:26079696 AGTR1 Human perfluorooctane-1-sulfonic acid decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in decreased expression of AGTR1A mRNA CTD PMID:19162173 AGTR1 Human perfluorooctane-1-sulfonic acid multiple interactions ISO Agtr1a (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of AGTR1A mRNA more ... CTD PMID:36331819 AGTR1 Human perfluorooctanoic acid decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 perfluorooctanoic acid results in decreased expression of AGTR1A mRNA CTD PMID:19162173 AGTR1 Human perindopril multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of AGTR1A mRNA] and Perindopril inhibits the reaction [Carbon Tetrachloride results in increased expression of AGTR1A protein] CTD PMID:12930639 and PMID:16097048 AGTR1 Human perindopril multiple interactions ISO Agtr1a (Mus musculus) 6480464 [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein] more ... CTD PMID:30184259 AGTR1 Human perindopril affects response to substance EXP 6480464 AGTR1 gene SNP affects the susceptibility to Perindopril CTD PMID:8952600 AGTR1 Human phenylarsine oxide multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 oxophenylarsine inhibits the reaction [[AGT protein binds to and results in increased localization of AGTR1A protein] which results in increased expression of PTGS2 protein] and oxophenylarsine inhibits the reaction [AGT protein binds to and results in increased localization of AGTR1A protein] CTD PMID:18267125 AGTR1 Human phosphane increases expression ISO Agtr1a (Rattus norvegicus) 6480464 phosphine results in increased expression of AGTR1 mRNA CTD PMID:34427094 AGTR1 Human picrotoxin increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Picrotoxin results in increased expression of AGTR1A mRNA CTD PMID:15170462 AGTR1 Human pioglitazone multiple interactions ISO Agtr1a (Mus musculus) 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGTR1A mRNA CTD PMID:27935865 AGTR1 Human pirfenidone decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 pirfenidone results in decreased expression of AGTR1 protein CTD PMID:28091615 AGTR1 Human pirinixic acid decreases expression ISO Agtr1a (Mus musculus) 6480464 pirinixic acid results in decreased expression of AGTR1A mRNA CTD PMID:25270620 AGTR1 Human pirinixic acid decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 pirinixic acid results in decreased expression of AGTR1A mRNA and pirinixic acid results in decreased expression of AGTR1A protein CTD PMID:18300857 and PMID:19162173 AGTR1 Human pirinixic acid affects expression ISO Agtr1a (Rattus norvegicus) 6480464 pirinixic acid affects the expression of AGTR1A mRNA CTD PMID:19483382 AGTR1 Human potassium chromate decreases expression EXP 6480464 potassium chromate(VI) results in decreased expression of AGTR1 mRNA CTD PMID:22079256 AGTR1 Human potassium chromate increases expression EXP 6480464 potassium chromate(VI) results in increased expression of AGTR1 mRNA CTD PMID:22714537 AGTR1 Human potassium chromate multiple interactions EXP 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AGTR1 mRNA CTD PMID:22079256 AGTR1 Human pregabalin increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Pregabalin results in increased expression of AGTR1 protein CTD PMID:31629013 AGTR1 Human pregabalin multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Captopril inhibits the reaction [Pregabalin results in increased expression of AGTR1 protein] and Telmisartan inhibits the reaction [Pregabalin results in increased expression of AGTR1 protein] CTD PMID:31629013 AGTR1 Human propanal decreases expression EXP 6480464 propionaldehyde results in decreased expression of AGTR1 mRNA CTD PMID:26079696 AGTR1 Human Ptaquiloside decreases expression ISO Agtr1a (Mus musculus) 6480464 ptaquiloside results in decreased expression of AGTR1A mRNA CTD PMID:23274088 AGTR1 Human quercetin multiple interactions ISO Agtr1a (Mus musculus) 6480464 Quercetin affects the reaction [Dietary Fats affects the expression of AGTR1A mRNA] CTD PMID:27260466 AGTR1 Human quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of AGTR1 mRNA CTD PMID:21632981 AGTR1 Human quercetin decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Quercetin results in decreased expression of AGTR1A mRNA CTD PMID:18356687 AGTR1 Human ramipril multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Ramipril inhibits the reaction [Doxorubicin results in increased expression of AGTR1A mRNA] CTD PMID:36636964 AGTR1 Human reactive oxygen species multiple interactions ISO Agtr1a (Mus musculus) 6480464 [AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased abundance of Reactive Oxygen Species CTD PMID:17620961 AGTR1 Human rebaudioside A increases expression EXP 6480464 rebaudioside A results in increased expression of AGTR1 mRNA CTD PMID:31655124 AGTR1 Human resveratrol decreases expression ISO Agtr1a (Mus musculus) 6480464 resveratrol results in decreased expression of AGTR1 protein CTD PMID:18420994 AGTR1 Human resveratrol decreases expression ISO Agtr1a (Rattus norvegicus) 401793709 resveratrol decreases expression of mRNA in kidney of male offspring from pregnant dams treated with 2 more ... RGD AGTR1 Human resveratrol multiple interactions ISO Agtr1a (Mus musculus) 6480464 resveratrol affects the reaction [Dietary Fats affects the expression of AGTR1A mRNA] CTD PMID:27260466 AGTR1 Human resveratrol multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Niacinamide results in decreased activity of SIRT1 protein] inhibits the reaction [resveratrol results in decreased expression of AGTR1 mRNA] CTD PMID:18420994 AGTR1 Human resveratrol decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 resveratrol results in decreased expression of AGTR1 mRNA and resveratrol results in decreased expression of AGTR1 protein CTD PMID:18420994 AGTR1 Human rotenone increases expression ISO Agtr1a (Mus musculus) 6480464 Rotenone results in increased expression of AGTR1A mRNA CTD PMID:29665408 AGTR1 Human rotenone decreases expression ISO Agtr1a (Mus musculus) 6480464 Rotenone results in decreased expression of AGTR1A mRNA CTD PMID:35919817 AGTR1 Human silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of AGTR1 mRNA CTD PMID:25895662 AGTR1 Human silicon dioxide increases expression ISO Agtr1a (Mus musculus) 6480464 Silicon Dioxide results in increased expression of AGTR1 protein CTD PMID:33007385 AGTR1 Human silicon dioxide multiple interactions ISO Agtr1a (Mus musculus) 6480464 7-Ala-angiotensin (1-7) promotes the reaction [Silicon Dioxide results in increased expression of AGTR1 protein] more ... CTD PMID:33007385 AGTR1 Human simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of AGTR1 mRNA CTD PMID:17513949 and PMID:18475152 AGTR1 Human sodium arsenite decreases expression ISO Agtr1a (Mus musculus) 6480464 sodium arsenite results in decreased expression of AGTR1A mRNA CTD PMID:25270620 AGTR1 Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of AGTR1 mRNA and sodium arsenite results in increased expression of AGTR1 protein CTD PMID:22714537 and PMID:28973481 AGTR1 Human sodium arsenite multiple interactions EXP 6480464 ERN1 affects the reaction [sodium arsenite results in increased expression of AGTR1 mRNA] more ... CTD PMID:28973481 AGTR1 Human sodium arsenite increases expression ISO Agtr1a (Mus musculus) 6480464 sodium arsenite results in increased expression of AGTR1 mRNA alternative form CTD PMID:23603059 AGTR1 Human sodium arsenite multiple interactions ISO Agtr1a (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of AGTR1 mRNA] and pyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of AGTR1 mRNA] CTD PMID:23603059 AGTR1 Human sodium fluoride increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Sodium Fluoride results in increased expression of AGTR1A mRNA and Sodium Fluoride results in increased expression of AGTR1A protein CTD PMID:37105417 AGTR1 Human spironolactone decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Spironolactone results in decreased expression of AGTR1 protein CTD PMID:18586661 and PMID:19114643 AGTR1 Human steviol increases expression EXP 6480464 steviol results in increased expression of AGTR1 mRNA CTD PMID:31655124 AGTR1 Human stevioside increases expression EXP 6480464 stevioside results in increased expression of AGTR1 mRNA CTD PMID:31655124 AGTR1 Human streptozocin multiple interactions ISO Agtr1a (Mus musculus) 6480464 2 more ... CTD PMID:21381899 more ... AGTR1 Human streptozocin multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA and esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA] CTD PMID:28946194 AGTR1 Human streptozocin increases expression ISO Agtr1a (Mus musculus) 6480464 Streptozocin results in increased expression of AGTR1 protein more ... CTD PMID:17724226 more ... AGTR1 Human sucrose multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Sucrose inhibits the reaction [[AGT protein binds to and results in increased localization of AGTR1A protein] which results in increased expression of PTGS2 protein] and Sucrose inhibits the reaction [AGT protein binds to and results in increased localization of AGTR1A protein] CTD PMID:18267125 AGTR1 Human superoxide multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [Mevinphos results in increased activity of AGTR1A protein] promotes the reaction [NOX1 protein results in increased abundance of Superoxides] CTD PMID:23824088 AGTR1 Human telmisartan decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 telmisartan results in decreased expression of AGTR1A mRNA CTD PMID:19171132 AGTR1 Human telmisartan decreases expression ISO Agtr1a (Rattus norvegicus) 329956421 telmisartan decreases expression of mRNA in mandible of rats with periodontal disease RGD AGTR1 Human telmisartan multiple interactions EXP 6480464 telmisartan binds to and results in decreased activity of AGTR1 protein CTD PMID:21557540 AGTR1 Human telmisartan multiple interactions ISO Agtr1a (Mus musculus) 6480464 telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] and telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein] CTD PMID:17620961 and PMID:21381899 AGTR1 Human telmisartan multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Telmisartan binds to and results in decreased activity of AGTR1 protein more ... CTD PMID:19706694 more ... AGTR1 Human telmisartan increases expression ISO Agtr1a (Rattus norvegicus) 6480464 telmisartan results in increased expression of AGTR1 mRNA CTD PMID:9533614 AGTR1 Human telmisartan affects binding ISO Agtr1a (Rattus norvegicus) 6480464 telmisartan binds to AGTR1 protein CTD PMID:8220885 AGTR1 Human testosterone affects response to substance ISO Agtr1a (Mus musculus) 6480464 AGTR1 protein affects the susceptibility to Testosterone CTD PMID:22539767 AGTR1 Human testosterone decreases expression ISO Agtr1a (Mus musculus) 6480464 Testosterone deficiency results in decreased expression of AGTR1A mRNA CTD PMID:33848595 AGTR1 Human testosterone multiple interactions ISO Agtr1a (Mus musculus) 6480464 1 more ... CTD PMID:33848595 AGTR1 Human testosterone increases expression ISO Agtr1a (Mus musculus) 6480464 Testosterone results in increased expression of AGTR1 mRNA CTD PMID:22539767 AGTR1 Human tetrachloromethane multiple interactions ISO Agtr1a (Mus musculus) 6480464 AGTR1A protein affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] and AGTR1A protein affects the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA] CTD PMID:12890498 AGTR1 Human tetrachloromethane multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Losartan inhibits the reaction [Carbon Tetrachloride results in increased expression of AGTR1A mRNA] more ... CTD PMID:12930639 and PMID:16097048 AGTR1 Human tetrachloromethane increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of AGTR1A mRNA and Carbon Tetrachloride results in increased expression of AGTR1A protein CTD PMID:12930639 and PMID:16097048 AGTR1 Human tetrachloromethane decreases expression ISO Agtr1a (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of AGTR1A mRNA CTD PMID:27339419 and PMID:31919559 AGTR1 Human tetraphene increases expression ISO Agtr1a (Mus musculus) 6480464 benz(a)anthracene results in increased expression of AGTR1A mRNA CTD PMID:26377693 AGTR1 Human thioacetamide affects expression ISO Agtr1a (Rattus norvegicus) 6480464 Thioacetamide affects the expression of AGTR1A mRNA CTD PMID:19483382 AGTR1 Human titanium dioxide decreases expression ISO Agtr1a (Mus musculus) 6480464 titanium dioxide results in decreased expression of AGTR1A mRNA CTD PMID:19464567 and PMID:23557971 AGTR1 Human topotecan multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of AGTR1A mRNA CTD PMID:25729387 AGTR1 Human tremolite asbestos decreases expression ISO Agtr1a (Mus musculus) 6480464 tremolite results in decreased expression of AGTR1A mRNA CTD PMID:29279043 AGTR1 Human triadimefon decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 triadimefon results in decreased expression of AGTR1 mRNA and triadimefon results in decreased expression of AGTR1 protein CTD PMID:34508824 AGTR1 Human tributylstannane increases expression ISO Agtr1a (Rattus norvegicus) 6480464 tributyltin results in increased expression of AGTR1A protein CTD PMID:30172001 AGTR1 Human trimellitic anhydride decreases expression ISO Agtr1a (Mus musculus) 6480464 trimellitic anhydride results in decreased expression of AGTR1A mRNA CTD PMID:19042947 AGTR1 Human triphenyl phosphate decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 triphenyl phosphate results in decreased expression of AGTR1A mRNA CTD PMID:30589522 AGTR1 Human triphenylstannane increases expression ISO Agtr1a (Rattus norvegicus) 6480464 triphenyltin results in increased expression of AGTR1 mRNA and triphenyltin results in increased expression of AGTR1 protein CTD PMID:31765896 AGTR1 Human troglitazone decreases expression ISO Agtr1a (Mus musculus) 6480464 troglitazone results in decreased expression of AGTR1 mRNA CTD PMID:28973697 AGTR1 Human tryptophan increases expression ISO Agtr1a (Rattus norvegicus) 401793718 tryptophan in pregnant dams increases expression of mRNA in kidney of male offspring RGD AGTR1 Human valproic acid multiple interactions ISO Agtr1a (Rattus norvegicus) 6480464 Valproic Acid promotes the reaction [Mechlorethamine results in increased expression of AGTR1A mRNA] CTD PMID:28184907 AGTR1 Human valproic acid increases expression ISO Agtr1a (Rattus norvegicus) 6480464 Valproic Acid results in increased expression of AGTR1A mRNA CTD PMID:29427782 AGTR1 Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of AGTR1 mRNA CTD PMID:28001369 and PMID:29154799 AGTR1 Human valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of AGTR1 mRNA CTD PMID:25979313 AGTR1 Human valsartan decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 Valsartan results in decreased expression of AGTR1A mRNA CTD PMID:18403896 AGTR1 Human valsartan multiple interactions ISO Agtr1a (Mus musculus) 6480464 Valsartan promotes the reaction [Streptozocin results in increased expression of AGTR1 protein] CTD PMID:29266779 AGTR1 Human valsartan multiple interactions EXP 6480464 Valsartan binds to and results in decreased activity of AGTR1 protein CTD PMID:28973481 AGTR1 Human vinclozolin decreases expression ISO Agtr1a (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of AGTR1A mRNA CTD PMID:23034163 AGTR1 Human warfarin multiple interactions EXP 6480464 epigallocatechin gallate promotes the reaction [Warfarin inhibits the reaction [Hydrogen Peroxide results in increased expression of AGTR1 mRNA]] more ... CTD PMID:36162953 AGTR1 Human zinc oxide decreases expression EXP 6480464 Zinc Oxide analog results in decreased expression of AGTR1 mRNA CTD PMID:27185063