Aqp3 (aquaporin 3) - Rat Genome Database

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Gene: Aqp3 (aquaporin 3) Mus musculus
Analyze
Symbol: Aqp3
Name: aquaporin 3
RGD ID: 68639
MGI Page MGI
Description: Predicted to enable channel activity; identical protein binding activity; and urea transmembrane transporter activity. Involved in glycerol transmembrane transport and water transport. Acts upstream of or within several processes, including renal water absorption; response to ischemia; and urea transport. Located in basolateral plasma membrane and cell-cell junction. Is expressed in several structures, including alimentary system; capillary; early conceptus; genitourinary system; and sensory organ. Used to study nephrogenic diabetes insipidus. Orthologous to human AQP3 (aquaporin 3 (Gill blood group)).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AQP-2; AQP-3; aquaglyceroporin-3; aquaporin-3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39441,092,724 - 41,098,183 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl441,092,722 - 41,098,183 (-)EnsemblGRCm39 Ensembl
GRCm38441,092,724 - 41,098,183 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl441,092,722 - 41,098,183 (-)EnsemblGRCm38mm10GRCm38
MGSCv37441,039,757 - 41,045,216 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36441,281,477 - 41,286,849 (-)NCBIMGSCv36mm8
Celera440,753,580 - 40,759,039 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map420.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,1-dichloroethene  (EXP)
1,10-phenanthroline  (ISO)
1,4-phenylenediamine  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methyl-1,4-phenylenediamine  (ISO)
2-palmitoylglycerol  (ISO)
3',5'-cyclic AMP  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
5-Nitro-2-(3-phenylpropylamino)benzoic acid  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
amphotericin B  (ISO)
ampicillin  (ISO)
antirheumatic drug  (ISO)
arachidonic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bortezomib  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
camptothecin  (ISO)
cannabidiol  (EXP,ISO)
captan  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chlorogenic acid  (ISO)
choline  (EXP)
ciglitazone  (ISO)
clofibrate  (ISO)
clofibric acid  (ISO)
Clofop  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
D-glucose  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dichlorine  (ISO)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
diprotium oxide  (ISO)
diquat  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
fenamic acid  (ISO)
fenofibrate  (ISO)
fluoxetine  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (ISO)
genistein  (ISO)
glucose  (ISO)
glycerol  (ISO)
hydroquinone  (ISO)
isoflavones  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
lucanthone  (ISO)
LY294002  (ISO)
malvidin 3-O-beta-D-glucoside  (ISO)
manganese(II) chloride  (ISO)
medroxyprogesterone acetate  (ISO)
mercaptoethanol  (ISO)
mercury dichloride  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
morphine  (ISO)
Muraglitazar  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nitrofen  (ISO)
Nutlin-3  (ISO)
Osajin  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
palmitoyl ethanolamide  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
petunidin 3-O-beta-D-glucoside  (ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP,ISO)
Pomiferin  (ISO)
proanthocyanidin  (ISO)
procyanidin B1  (ISO)
procyanidin B3  (ISO)
progesterone  (ISO)
propanal  (ISO)
puerarin  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
resorcinol  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
Rosavin  (ISO)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
selenium atom  (ISO)
serotonin  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
sulforaphane  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
thiourea  (ISO)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
triacsin C  (ISO)
triptonide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vitamin E  (ISO)
water  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
basolateral plasma membrane  (IBA,IDA,ISO)
cell-cell junction  (IDA,ISO)
cytoplasm  (IEA,ISO)
membrane  (IEA)
nucleoplasm  (IEA,ISO)
plasma membrane  (IBA,IDA,ISO,TAS)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Urinary concentrating defect in hypothyroid rats: role of sodium, potassium, 2-chloride co-transporter, and aquaporins. Cadnapaphornchai MA, etal., J Am Soc Nephrol 2003 Mar;14(3):566-74.
2. Human neuronal changes in brain edema and increased intracranial pressure. Faragó N, etal., Acta Neuropathol Commun. 2016 Aug 4;4(1):78. doi: 10.1186/s40478-016-0356-x.
3. Aquaporins in the kidney. Kwon TH, etal., Handb Exp Pharmacol. 2009;(190):95-132. doi: 10.1007/978-3-540-79885-9_5.
4. Impaired hearing in mice lacking aquaporin-4 water channels. Li J and Verkman AS, J Biol Chem 2001 Aug 17;276(33):31233-7. Epub 2001 Jun 13.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. Mouse MP Annotation Import Pipeline RGD automated import pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia. Yang M, etal., Brain Res. 2009 Sep 22;1290:121-32. Epub 2009 Jul 16.
Additional References at PubMed
PMID:9276712   PMID:9757370   PMID:10232700   PMID:10322639   PMID:10349636   PMID:10737773   PMID:10777495   PMID:10788316   PMID:10795927   PMID:10870513   PMID:11035042   PMID:11042159  
PMID:11066060   PMID:11076861   PMID:11078688   PMID:11217851   PMID:11382807   PMID:11443343   PMID:11880378   PMID:12031518   PMID:12042359   PMID:12270942   PMID:12477932   PMID:12565800  
PMID:12679107   PMID:14610273   PMID:14675200   PMID:15003543   PMID:15100356   PMID:15489334   PMID:15550389   PMID:15557451   PMID:15815633   PMID:15844003   PMID:15966863   PMID:16079275  
PMID:16135541   PMID:16141072   PMID:16141073   PMID:16339044   PMID:16476579   PMID:16525162   PMID:16602821   PMID:16889624   PMID:16973757   PMID:17003427   PMID:17377981   PMID:17429015  
PMID:17597824   PMID:17967887   PMID:17968524   PMID:18172001   PMID:18177851   PMID:18209479   PMID:19136711   PMID:19184071   PMID:19237298   PMID:19258345   PMID:19367412   PMID:19855135  
PMID:20121927   PMID:20364088   PMID:20487527   PMID:20509986   PMID:20724658   PMID:20957496   PMID:21135872   PMID:21178974   PMID:21191421   PMID:21267068   PMID:21276418   PMID:21457357  
PMID:21523854   PMID:21677750   PMID:21721139   PMID:21735643   PMID:21865318   PMID:21871666   PMID:21873635   PMID:22138657   PMID:22237802   PMID:22479204   PMID:22927550   PMID:23243273  
PMID:24194600   PMID:24418925   PMID:24462679   PMID:24904084   PMID:25215286   PMID:25233074   PMID:25473914   PMID:25803581   PMID:26100668   PMID:26348407   PMID:26454884   PMID:26847765  
PMID:27138166   PMID:27165276   PMID:27265621   PMID:27362799   PMID:27384406   PMID:27524635   PMID:27626380   PMID:28049834   PMID:28111811   PMID:28344130   PMID:28384265   PMID:28526298  
PMID:28853179   PMID:29207043   PMID:29237740   PMID:29357412   PMID:29626438   PMID:30025158   PMID:30768374   PMID:31036716   PMID:31382467   PMID:31582652   PMID:31953689   PMID:32186673  
PMID:32325033   PMID:32467224   PMID:32542408   PMID:32857879   PMID:33078411   PMID:33168815   PMID:33232321   PMID:34540996   PMID:36343245   PMID:36674890   PMID:37641009   PMID:37928265  
PMID:38354944   PMID:38355793   PMID:39047740  


Genomics

Comparative Map Data
Aqp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39441,092,724 - 41,098,183 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl441,092,722 - 41,098,183 (-)EnsemblGRCm39 Ensembl
GRCm38441,092,724 - 41,098,183 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl441,092,722 - 41,098,183 (-)EnsemblGRCm38mm10GRCm38
MGSCv37441,039,757 - 41,045,216 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36441,281,477 - 41,286,849 (-)NCBIMGSCv36mm8
Celera440,753,580 - 40,759,039 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map420.94NCBI
AQP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38933,441,160 - 33,447,593 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl933,441,156 - 33,447,596 (-)EnsemblGRCh38hg38GRCh38
GRCh37933,441,158 - 33,447,591 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,431,158 - 33,437,590 (-)NCBINCBI36Build 36hg18NCBI36
Build 34933,431,161 - 33,437,590NCBI
Celera933,371,265 - 33,377,697 (-)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef933,397,455 - 33,403,933 (-)NCBIHuRef
CHM1_1933,440,929 - 33,447,408 (-)NCBICHM1_1
T2T-CHM13v2.0933,459,659 - 33,466,091 (-)NCBIT2T-CHM13v2.0
Aqp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8561,035,165 - 61,040,683 (-)NCBIGRCr8
mRatBN7.2556,239,200 - 56,244,718 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl556,239,201 - 56,244,720 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx558,214,542 - 58,220,027 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0560,033,565 - 60,039,050 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0560,018,965 - 60,024,339 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0557,423,735 - 57,429,252 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,423,734 - 57,429,245 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0561,954,830 - 61,960,347 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4558,501,642 - 58,507,159 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1558,501,820 - 58,507,338 (-)NCBI
Celera554,836,731 - 54,842,234 (-)NCBICelera
Cytogenetic Map5q22NCBI
Aqp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554722,234,770 - 2,240,027 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554722,234,770 - 2,239,753 (+)NCBIChiLan1.0ChiLan1.0
AQP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21191,153,391 - 91,159,857 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1991,159,328 - 91,165,801 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0933,221,989 - 33,228,469 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1934,032,983 - 34,039,438 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl934,032,983 - 34,039,438 (-)Ensemblpanpan1.1panPan2
AQP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11150,517,509 - 50,524,565 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1149,147,497 - 49,154,480 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01151,458,242 - 51,465,233 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1151,458,249 - 51,464,338 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11150,122,208 - 50,128,303 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01149,989,326 - 49,996,305 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01150,754,568 - 50,761,559 (-)NCBIUU_Cfam_GSD_1.0
Aqp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947165,416,549 - 165,422,364 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365241,963,247 - 1,969,998 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365241,963,427 - 1,969,977 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AQP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1033,045,245 - 33,051,082 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11033,045,374 - 33,050,285 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21037,307,632 - 37,312,545 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AQP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11246,817,790 - 46,825,154 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603843,708,128 - 43,714,966 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aqp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473638,194,545 - 38,201,036 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473638,194,722 - 38,200,961 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aqp3
137 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:536
Count of miRNA genes:364
Interacting mature miRNAs:410
Transcripts:ENSMUST00000055327, ENSMUST00000154722
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1558992Ses8_msalmonella enteritidis susceptibility 8 (mouse)Not determined4868324042683429Mouse
4141302Ssrq5_mstress response QTL 5 (mouse)Not determined868324042683430Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663283678Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1302010Wta1_mweight adult 1 (mouse)Not determined4868324042683429Mouse
4142290Ssrq9_mstress response QTL 9 (mouse)Not determined3439516046332776Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
1301473Triglq1_mtriglyceride QTL 1 (mouse)Not determined4868324042683429Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
1302125Lxw1_mlupus BXSB x NZW 1 (mouse)Not determined4868324042683429Mouse

Markers in Region
Aqp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37441,040,597 - 41,041,339UniSTSGRCm37
Celera440,754,420 - 40,755,162UniSTS
Cytogenetic Map4B1UniSTS
cM MapUN UniSTS
cM Map4 UniSTS
MARC_26051-26052:1032543524:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38441,093,630 - 41,093,873UniSTSGRCm38
MGSCv37441,040,663 - 41,040,906UniSTSGRCm37
Celera440,754,486 - 40,754,729UniSTS
Cytogenetic Map4B1UniSTS
Aqp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS
cM MapUN UniSTS
cM Map4 UniSTS
Aqp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38441,093,564 - 41,094,306UniSTSGRCm38
MGSCv37441,040,597 - 41,041,339UniSTSGRCm37
Celera440,754,420 - 40,755,162UniSTS
Cytogenetic Map4B1UniSTS
cM MapUN UniSTS


Sequence


Ensembl Acc Id: ENSMUST00000055327   ⟹   ENSMUSP00000055110
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,092,722 - 41,098,183 (-)Ensembl
GRCm38.p6 Ensembl441,092,722 - 41,098,183 (-)Ensembl
Ensembl Acc Id: ENSMUST00000154722
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl441,093,782 - 41,094,448 (-)Ensembl
GRCm38.p6 Ensembl441,093,782 - 41,094,448 (-)Ensembl
RefSeq Acc Id: NM_016689   ⟹   NP_057898
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39441,092,724 - 41,098,183 (-)NCBI
GRCm38441,092,724 - 41,098,183 (-)ENTREZGENE
MGSCv37441,039,757 - 41,045,216 (-)RGD
Celera440,753,580 - 40,759,039 (-)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_057898   ⟸   NM_016689
- UniProtKB: Q9JJN8 (UniProtKB/Swiss-Prot),   Q3TU75 (UniProtKB/Swiss-Prot),   Q9WTJ3 (UniProtKB/Swiss-Prot),   Q8R2N1 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000055110   ⟸   ENSMUST00000055327

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R2N1-F1-model_v2 AlphaFold Q8R2N1 1-292 view protein structure

Promoters
RGD ID:6834883
Promoter ID:MM_KWN:37137
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000015099
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36441,044,901 - 41,045,401 (-)MPROMDB
RGD ID:6883118
Promoter ID:EPDNEW_M4991
Type:multiple initiation site
Name:Aqp3_1
Description:Mus musculus aquaporin 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38441,098,183 - 41,098,243EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1333777 AgrOrtholog
Ensembl Genes ENSMUSG00000028435 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000055327 ENTREZGENE
  ENSMUST00000055327.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1080.10 UniProtKB/Swiss-Prot
InterPro Aquaporin-like UniProtKB/Swiss-Prot
  Aquaporin_3 UniProtKB/Swiss-Prot
  MIP UniProtKB/Swiss-Prot
  MIP/Aquaporin UniProtKB/Swiss-Prot
  MIP_CS UniProtKB/Swiss-Prot
KEGG Report mmu:11828 UniProtKB/Swiss-Prot
MGD MGI:1333777 ENTREZGENE
NCBI Gene 11828 ENTREZGENE
PANTHER AQUAPORIN OR AQUAGLYCEROPORIN RELATED UniProtKB/Swiss-Prot
  AQUAPORIN-3 UniProtKB/Swiss-Prot
Pfam MIP UniProtKB/Swiss-Prot
PhenoGen Aqp3 PhenoGen
PRINTS AQUAPORIN3 UniProtKB/Swiss-Prot
  MINTRINSICP UniProtKB/Swiss-Prot
PROSITE MIP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF81338 UniProtKB/Swiss-Prot
UniProt AQP3_MOUSE UniProtKB/Swiss-Prot
  Q3TU75 ENTREZGENE
  Q8R2N1 ENTREZGENE
  Q9JJN8 ENTREZGENE
  Q9WTJ3 ENTREZGENE
UniProt Secondary Q3TU75 UniProtKB/Swiss-Prot
  Q9JJN8 UniProtKB/Swiss-Prot
  Q9WTJ3 UniProtKB/Swiss-Prot